CN113750211A - Medicine and food homologous traditional Chinese medicine formula for treating lochiorrhea in puerperium women - Google Patents

Medicine and food homologous traditional Chinese medicine formula for treating lochiorrhea in puerperium women Download PDF

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CN113750211A
CN113750211A CN202111026612.4A CN202111026612A CN113750211A CN 113750211 A CN113750211 A CN 113750211A CN 202111026612 A CN202111026612 A CN 202111026612A CN 113750211 A CN113750211 A CN 113750211A
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lochia
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徐爱芳
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Xuzhou Kangzheng Traditional Chinese Medicine Technology Co ltd
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/906Zingiberaceae (Ginger family)
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    • AHUMAN NECESSITIES
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    • A61K9/2004Excipients; Inactive ingredients
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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Abstract

The invention discloses a traditional Chinese medicine prescription with homology of medicine and food for lochia elimination of women in puerperium, which comprises the following components: 10-20 parts of cassia twig, 10-20 parts of tuckahoe, 10-20 parts of tree peony bark, 10-20 parts of peach kernel, 10-20 parts of red paeony root, 5-10 parts of American ginseng, 5-10 parts of baked ginger and 20-30 parts of fresh Chinese yam. The invention creatively adds the American ginseng, the baked ginger and the fresh yam on the basis of the cassia twig and tuckahoe pills. The American ginseng tonifies middle-jiao energy, can enhance the immunity of a puerpera and reduce the risk of intrauterine infection; the baked ginger can warm the channels, stop bleeding and relieve pain, and can relieve the discomfort of the puerpera after delivery; the Chinese yam leucorrhea can promote the discharge of intrauterine contents, and meanwhile, fresh Chinese yam can contain abundant mucin, so that the activity of the uterus can be increased, and the recovery speed of the uterus can be improved. The invention can quickly discharge the postpartum lochia of the female, reduce the occurrence of intrauterine infection and accelerate the recovery of the female body.

Description

Medicine and food homologous traditional Chinese medicine formula for treating lochiorrhea in puerperium women
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a medicine-food homologous traditional Chinese medicine formula for lochia elimination of women in puerperium.
Background
Postpartum lochia refers to postpartum decidua accompanying with uterus, and contains tissues such as blood, necrotic decidua, etc. which are discharged through vagina, and is called lochia. Lochia is the clinical manifestation of a parturient in puerperium and belongs to physiological changes. The lochia has a bloody smell but no odor, and its color and content change with time, generally lasting 4-6 weeks, and the total amount is about 500 mL. If more lochia is still excreted beyond the above events, it is called as incomplete postpartum lochia.
The postpartum lochiorrhea is caused by a plurality of reasons, and the common causes are as follows: there are residues of tissue, infection of uterine cavity and uterine weakness. Incomplete lochia can increase the incidence of uterine infection, and can cause hemorrhagic anemia, seriously harming the physical health of puerperae and infants.
Therefore, the lying-in women need an important formula which can assist in expelling the lochia.
Disclosure of Invention
In order to solve the technical problems, the invention discloses a medicine and food homologous traditional Chinese medicine formula for lochia elimination of women in puerperium. In order to achieve the purpose, the invention adopts the following technical scheme:
a traditional Chinese medicine prescription with homology of medicine and food for lochiorrhea of women in puerperium comprises the following components:
10-20 parts of cassia twig, 10-20 parts of tuckahoe, 10-20 parts of tree peony bark, 10-20 parts of peach kernel, 10-20 parts of red paeony root, 5-10 parts of American ginseng, 5-10 parts of baked ginger and 20-30 parts of fresh Chinese yam.
The invention also discloses a preparation method of the medicine-food homologous traditional Chinese medicine prescription for treating lochiorrhea of women in puerperium, which comprises the following steps:
s1, weighing raw materials in proportion, cleaning and removing impurities;
s2, grinding the cassia twig, the poria cocos, the tree peony bark, the peach kernel, the red paeony root, the American ginseng and the baked ginger into powder, sieving and uniformly mixing;
s3, peeling fresh Chinese yam, grinding into thick liquid, and freeze-drying to obtain Chinese yam powder;
s3, uniformly mixing the Chinese yam powder and the medicinal material powder obtained in the step S2, adding water and honey, and refining the honey into pills.
As an improvement, the medicinal material powder in the step S2 is sieved by a 200-mesh sieve.
Cassia twig, pungent and sweet in flavor and warm in nature; it enters heart, lung and bladder meridians. Has the effects of inducing sweat, expelling pathogenic factors from muscles, warming and activating meridians, supporting yang, and regulating qi. It can be used for treating common cold due to wind-cold, pain due to cold accumulation and blood stagnation, phlegm retention, water retention syndrome, and palpitation.
Poria cocos, sweet and light in flavor, mild in nature; it enters heart, lung, spleen and kidney meridians. Has effects of promoting diuresis, eliminating dampness, invigorating spleen, and calming heart. It can be used for treating edema, phlegm retention, diarrhea due to spleen deficiency, palpitation, and insomnia.
Moutan bark, cortex moutan, bitter, pungent and slightly cold; it enters heart, liver and kidney meridians. Has effects of clearing heat, cooling blood, promoting blood circulation, and removing blood stasis. It can be used for treating warm toxic macula, hematemesis, epistaxis, yin injury due to epidemic febrile disease, fever due to yin deficiency, night fever, morning cool, anidrosis, bone steaming, amenorrhea due to blood stagnation, dysmenorrhea, traumatic injury, pain, carbuncle, swelling, and skin sore.
Peach kernel, bitter, sweet and neutral; it enters heart, liver and large intestine meridians. Has the effects of promoting blood circulation, removing blood stasis, loosening bowel to relieve constipation, and relieving cough and asthma. Can be used for treating amenorrhea, dysmenorrhea, abdominal mass, pulmonary abscess, intestinal carbuncle, traumatic injury, intestinal dryness, constipation, cough, and asthma.
Red peony root, bitter in taste, slightly cold in nature; it enters liver meridian. Has the effects of clearing heat, cooling blood, promoting blood circulation and removing blood stasis. It can be used for treating macula due to toxic heat, hematemesis, epistaxis, conjunctival congestion, swelling and pain, carbuncle, swelling, sore, ulcer, stagnation of liver-qi, hypochondriac pain, amenorrhea, dysmenorrhea, abdominal mass, abdominal pain, and traumatic injury.
American ginseng, sweet and slightly bitter, cool; enter heart, lung and kidney meridians. Has the effects of benefiting lung yin, clearing deficient fire, promoting fluid production and quenching thirst. It is indicated for chronic cough due to lung deficiency, blood loss, dry throat, thirst, deficiency heat, restlessness and fatigue.
Baked ginger, pungent and hot; it enters spleen, stomach and kidney meridians. Has effects of warming channels, stopping bleeding, warming middle-jiao and relieving pain. Can be used for treating yang deficiency, hemorrhage, hematemesis, metrorrhagia, metrostaxis, spleen and stomach deficiency cold, abdominal pain, vomiting and diarrhea.
Chinese yam, sweet and neutral; enter lung, spleen and kidney meridians. Has effects in invigorating spleen, tonifying lung, reinforcing kidney, and replenishing vital essence. It is effective in treating diarrhea due to spleen deficiency, chronic dysentery, cough due to asthenia, diabetes, spermatorrhea, and leukorrhagia.
By adopting the technical scheme, the beneficial effects are as follows:
the invention discloses a traditional Chinese medicine prescription with homology of medicine and food for lochia elimination of women in puerperium. The scheme creatively adds the American ginseng, the baked ginger and the fresh Chinese yam on the basis of the cassia twig and tuckahoe pills. The American ginseng tonifies middle-jiao energy, can enhance the immunity of a puerpera and reduce the risk of intrauterine infection; the baked ginger can warm the channels, stop bleeding and relieve pain, and can relieve the discomfort of the puerpera after delivery; the Chinese yam leucorrhea can promote the discharge of intrauterine contents, and meanwhile, fresh Chinese yam can contain abundant mucin, so that the activity of the uterus can be increased, and the recovery speed of the uterus can be improved.
The invention can quickly discharge the postpartum lochia of the female, reduce the occurrence of intrauterine infection and accelerate the recovery of the female body.
Detailed Description
The present invention will be described in detail and specifically with reference to the following examples so as to facilitate the understanding of the present invention, but the following examples do not limit the scope of the present invention.
Example 1
The embodiment discloses a medicine and food homologous traditional Chinese medicine formula for treating lochiorrhea in puerperium women, which comprises the following components:
20g of cassia twig, 20g of tuckahoe, 20g of tree peony bark, 20g of peach kernel, 20g of red paeony root, 10g of American ginseng, 8g of baked ginger and 30g of fresh yam.
The invention also discloses a preparation method of the medicine-food homologous traditional Chinese medicine prescription for treating lochiorrhea of women in puerperium, which comprises the following steps:
s1, weighing raw materials in proportion, cleaning and removing impurities;
s2, grinding the cassia twig, the poria cocos, the tree peony bark, the peach kernel, the red paeony root, the American ginseng and the baked ginger into powder, sieving the powder by a 200-mesh sieve, and uniformly mixing the powder;
s3, peeling fresh Chinese yam, grinding into thick liquid, and freeze-drying to obtain Chinese yam powder;
s3, uniformly mixing the Chinese yam powder and the medicinal material powder obtained in the step S2, adding water and honey, and refining the honey into pills.
Example 2
The embodiment discloses a medicine and food homologous traditional Chinese medicine formula for treating lochiorrhea in puerperium women, which comprises the following components:
20g of cassia twig, 15g of tuckahoe, 20g of tree peony bark, 20g of peach kernel, 20g of red paeony root, 10g of American ginseng, 5g of baked ginger and 20g of fresh yam.
The manufacturing method of this example is the same as example 1.
The invention carries out a verification experiment on the scheme of the embodiment 1:
the random control test is carried out on the parturients collected from 1 month to 2021 month in 2020, the total number of the parturients is 130, wherein 65 in the experimental group and 65 in the control group are included.
Selecting a standard for a puerpera: the product is 25-40 years old, and has the symptoms of normal function of liver and kidney, normal blood coagulation, no abnormal platelet and malignant tumor, etc. Participate in signing the informed consent of the puerpera.
Experimental groups: the protocol of example 1 was used starting on the first day after delivery; control group: guizhi Fuling Wan is used on the first day after delivery.
The taking method comprises the following steps: the experimental group and the control group are 2 times per day, and 6 pills are taken each time.
The results are as follows:
TABLE 1 comparison of the amount of lochia after treatment
Figure BDA0003243768700000031
As can be seen from Table 1, the amount of lochia of the postpartum experimental group and the control group is not statistically different, but after 5 days of treatment, the amount of lochia of the experimental group is obviously reduced compared with the control group, and the statistical significance is achieved (P is less than 0.05); after 15 days of treatment, the experimental group of lying-in women has no lochia basically, while the control group of lying-in women still has a small amount of lochia to flow out. According to the statistical data, the mean treatment time for the experimental group to drain lochia was 14.22 days, while the mean treatment time for the control group was 16.75 days, and the difference was statistically significant (P < 0.05). The invention can effectively reduce the amount of the puerperal lochia and accelerate the excretion of the puerperal lochia.
The present invention and the embodiments thereof have been described above, but the description is not limited thereto, and the embodiments shown in the above embodiments are only one of the embodiments of the present invention, and the actual configuration is not limited thereto. In summary, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (4)

1. A medicine-food homologous traditional Chinese medicine formula for expelling lochia in puerperal women is characterized by comprising the following components:
10-20 parts of cassia twig, 10-20 parts of tuckahoe, 10-20 parts of tree peony bark, 10-20 parts of peach kernel, 10-20 parts of red paeony root, 5-10 parts of American ginseng, 5-10 parts of baked ginger and 20-30 parts of fresh Chinese yam.
2. The medicine-food homologous traditional Chinese medicine formula for treating lochia of puerperal women according to claim 1, which is characterized in that the traditional Chinese medicine formula is prepared into honeyed pills.
3. A preparation method of the medicine-food homologous traditional Chinese medicine formula for treating lochia of puerperal women according to claim 1 is characterized by comprising the following steps:
s1, weighing raw materials in proportion, cleaning and removing impurities;
s2, grinding the cassia twig, the poria cocos, the tree peony bark, the peach kernel, the red paeony root, the American ginseng and the baked ginger into powder, sieving and uniformly mixing;
s3, peeling fresh Chinese yam, grinding into thick liquid, and freeze-drying to obtain Chinese yam powder;
s3, uniformly mixing the Chinese yam powder and the medicinal material powder obtained in the step S2, adding water and honey, and refining the honey into pills.
4. The preparation method of the medicine-food homologous traditional Chinese medicine for treating lochia of the puerperal women according to claim 3, wherein the medicinal material powder in the step S2 is sieved by a 200-mesh sieve.
CN202111026612.4A 2021-09-02 2021-09-02 Medicine and food homologous traditional Chinese medicine formula for treating lochiorrhea in puerperium women Pending CN113750211A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1533799A (en) * 2003-03-28 2004-10-06 浙江可立思安制药有限公司 Chinese medicinal tablet for treating gynecopathy and its preparation process
CN1615978A (en) * 2004-09-10 2005-05-18 张凯 Cassia twig and poria cocos disperse tablet and its producing method
CN107308234A (en) * 2017-08-04 2017-11-03 山西正元盛邦制药有限公司 A kind of preparation method of guizhi fuling pill

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1533799A (en) * 2003-03-28 2004-10-06 浙江可立思安制药有限公司 Chinese medicinal tablet for treating gynecopathy and its preparation process
CN1615978A (en) * 2004-09-10 2005-05-18 张凯 Cassia twig and poria cocos disperse tablet and its producing method
CN107308234A (en) * 2017-08-04 2017-11-03 山西正元盛邦制药有限公司 A kind of preparation method of guizhi fuling pill

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冯宗文: "《女性免疫性不孕不育的中医诊治》", 31 August 2017, 中国中医药出版社 *
张其江: "桂枝茯苓丸在妇科血证中的应用", 《山东中医杂志》 *
於莉英 等: "桂枝茯苓胶囊联合抗生素治疗恶露不净效果观察", 《现代中西医结合杂志》 *
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