CN113750011A - Pet tartar removing liquid and preparation method thereof - Google Patents
Pet tartar removing liquid and preparation method thereof Download PDFInfo
- Publication number
- CN113750011A CN113750011A CN202111175516.6A CN202111175516A CN113750011A CN 113750011 A CN113750011 A CN 113750011A CN 202111175516 A CN202111175516 A CN 202111175516A CN 113750011 A CN113750011 A CN 113750011A
- Authority
- CN
- China
- Prior art keywords
- parts
- pet
- acid
- vitamin
- tartar removal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000006558 Dental Calculus Diseases 0.000 title claims abstract description 33
- 239000007788 liquid Substances 0.000 title claims abstract description 18
- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims abstract description 21
- 239000004327 boric acid Substances 0.000 claims abstract description 21
- 229940088594 vitamin Drugs 0.000 claims abstract description 19
- 229930003231 vitamin Natural products 0.000 claims abstract description 19
- 235000013343 vitamin Nutrition 0.000 claims abstract description 19
- 239000011782 vitamin Substances 0.000 claims abstract description 19
- 230000003115 biocidal effect Effects 0.000 claims abstract description 13
- 150000003722 vitamin derivatives Chemical class 0.000 claims abstract description 12
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 41
- 239000000203 mixture Substances 0.000 claims description 24
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical compound ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 claims description 23
- 150000003839 salts Chemical class 0.000 claims description 22
- 229920001864 tannin Polymers 0.000 claims description 22
- 235000018553 tannin Nutrition 0.000 claims description 22
- 239000001648 tannin Substances 0.000 claims description 22
- 235000011511 Diospyros Nutrition 0.000 claims description 21
- 239000000284 extract Substances 0.000 claims description 21
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims description 21
- 239000000419 plant extract Substances 0.000 claims description 20
- 235000017557 sodium bicarbonate Nutrition 0.000 claims description 20
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 claims description 19
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 claims description 19
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 claims description 19
- 229920000388 Polyphosphate Polymers 0.000 claims description 19
- 241000220317 Rosa Species 0.000 claims description 19
- 229940074393 chlorogenic acid Drugs 0.000 claims description 19
- 235000001368 chlorogenic acid Nutrition 0.000 claims description 19
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 claims description 19
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 claims description 19
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 claims description 19
- 239000001205 polyphosphate Substances 0.000 claims description 19
- 235000011176 polyphosphates Nutrition 0.000 claims description 19
- 244000236655 Diospyros kaki Species 0.000 claims description 18
- 239000007853 buffer solution Substances 0.000 claims description 15
- IPWKIXLWTCNBKN-UHFFFAOYSA-N Madelen Chemical compound CC1=NC=C([N+]([O-])=O)N1CC(O)CCl IPWKIXLWTCNBKN-UHFFFAOYSA-N 0.000 claims description 13
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims description 13
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims description 12
- 229960002313 ornidazole Drugs 0.000 claims description 12
- 229960002477 riboflavin Drugs 0.000 claims description 12
- 229930003471 Vitamin B2 Natural products 0.000 claims description 11
- 239000003242 anti bacterial agent Substances 0.000 claims description 11
- 239000011716 vitamin B2 Substances 0.000 claims description 11
- 235000019164 vitamin B2 Nutrition 0.000 claims description 11
- 229940088710 antibiotic agent Drugs 0.000 claims description 10
- 229960002645 boric acid Drugs 0.000 claims description 10
- 238000002156 mixing Methods 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- 239000012530 fluid Substances 0.000 claims 6
- 241000894006 Bacteria Species 0.000 abstract description 11
- 230000012010 growth Effects 0.000 abstract description 8
- 210000000214 mouth Anatomy 0.000 abstract description 7
- 206010044029 Tooth deposit Diseases 0.000 abstract description 5
- 230000006378 damage Effects 0.000 abstract description 5
- 230000036039 immunity Effects 0.000 abstract description 2
- 238000010419 pet care Methods 0.000 abstract description 2
- 239000000306 component Substances 0.000 description 14
- 239000000126 substance Substances 0.000 description 9
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 7
- 239000000872 buffer Substances 0.000 description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 241000196324 Embryophyta Species 0.000 description 5
- 239000002253 acid Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 235000013824 polyphenols Nutrition 0.000 description 5
- 241001465754 Metazoa Species 0.000 description 4
- 241000700159 Rattus Species 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 208000007565 gingivitis Diseases 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 150000008442 polyphenolic compounds Chemical class 0.000 description 4
- 241000205585 Aquilegia canadensis Species 0.000 description 3
- 241000606125 Bacteroides Species 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- 229910002092 carbon dioxide Inorganic materials 0.000 description 3
- 239000013078 crystal Substances 0.000 description 3
- 208000002925 dental caries Diseases 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 206010006326 Breath odour Diseases 0.000 description 2
- 241000167550 Centella Species 0.000 description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 2
- 244000035851 Chrysanthemum leucanthemum Species 0.000 description 2
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 2
- 241000193403 Clostridium Species 0.000 description 2
- 241000723267 Diospyros Species 0.000 description 2
- 244000303040 Glycyrrhiza glabra Species 0.000 description 2
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 description 2
- 208000032139 Halitosis Diseases 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 239000007836 KH2PO4 Substances 0.000 description 2
- 241000219784 Sophora Species 0.000 description 2
- 244000269722 Thea sinensis Species 0.000 description 2
- 230000003385 bacteriostatic effect Effects 0.000 description 2
- 229910021538 borax Inorganic materials 0.000 description 2
- 239000001569 carbon dioxide Substances 0.000 description 2
- 231100000357 carcinogen Toxicity 0.000 description 2
- 239000003183 carcinogenic agent Substances 0.000 description 2
- YCIMNLLNPGFGHC-UHFFFAOYSA-N catechol Chemical compound OC1=CC=CC=C1O YCIMNLLNPGFGHC-UHFFFAOYSA-N 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000000460 chlorine Substances 0.000 description 2
- 229910052801 chlorine Inorganic materials 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 239000000645 desinfectant Substances 0.000 description 2
- 229910000397 disodium phosphate Inorganic materials 0.000 description 2
- 235000005686 eating Nutrition 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 230000002452 interceptive effect Effects 0.000 description 2
- 235000011477 liquorice Nutrition 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 2
- 210000002200 mouth mucosa Anatomy 0.000 description 2
- 239000002324 mouth wash Substances 0.000 description 2
- 229940051866 mouthwash Drugs 0.000 description 2
- 239000003002 pH adjusting agent Substances 0.000 description 2
- 208000028169 periodontal disease Diseases 0.000 description 2
- 239000002953 phosphate buffered saline Substances 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 2
- 239000004299 sodium benzoate Substances 0.000 description 2
- 235000010234 sodium benzoate Nutrition 0.000 description 2
- 239000004328 sodium tetraborate Substances 0.000 description 2
- 235000010339 sodium tetraborate Nutrition 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- QAIPRVGONGVQAS-DUXPYHPUSA-N trans-caffeic acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 description 2
- ACEAELOMUCBPJP-UHFFFAOYSA-N (E)-3,4,5-trihydroxycinnamic acid Natural products OC(=O)C=CC1=CC(O)=C(O)C(O)=C1 ACEAELOMUCBPJP-UHFFFAOYSA-N 0.000 description 1
- VYDWQPKRHOGLPA-UHFFFAOYSA-N 5-nitroimidazole Chemical compound [O-][N+](=O)C1=CN=CN1 VYDWQPKRHOGLPA-UHFFFAOYSA-N 0.000 description 1
- 241000186361 Actinobacteria <class> Species 0.000 description 1
- 206010001497 Agitation Diseases 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 108010077805 Bacterial Proteins Proteins 0.000 description 1
- 241000606124 Bacteroides fragilis Species 0.000 description 1
- 241001135228 Bacteroides ovatus Species 0.000 description 1
- 241000606123 Bacteroides thetaiotaomicron Species 0.000 description 1
- 241000606215 Bacteroides vulgatus Species 0.000 description 1
- 208000005623 Carcinogenesis Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 206010010741 Conjunctivitis Diseases 0.000 description 1
- 208000002064 Dental Plaque Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 244000055850 Diospyros virginiana Species 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 241000186394 Eubacterium Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 208000005232 Glossitis Diseases 0.000 description 1
- 241000590002 Helicobacter pylori Species 0.000 description 1
- 241000544912 Melanoides Species 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 241000206591 Peptococcus Species 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
- 208000008312 Tooth Loss Diseases 0.000 description 1
- 241000607598 Vibrio Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 201000003465 angular cheilitis Diseases 0.000 description 1
- 230000003610 anti-gingivitis Effects 0.000 description 1
- 230000002223 anti-pathogen Effects 0.000 description 1
- 230000003260 anti-sepsis Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000941 bile Anatomy 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000004061 bleaching Methods 0.000 description 1
- 239000007844 bleaching agent Substances 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- 230000003139 buffering effect Effects 0.000 description 1
- 235000004883 caffeic acid Nutrition 0.000 description 1
- 229940074360 caffeic acid Drugs 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 230000036952 cancer formation Effects 0.000 description 1
- 230000000711 cancerogenic effect Effects 0.000 description 1
- 231100000504 carcinogenesis Toxicity 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000011712 cell development Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 208000007287 cheilitis Diseases 0.000 description 1
- 230000001989 choleretic effect Effects 0.000 description 1
- QAIPRVGONGVQAS-UHFFFAOYSA-N cis-caffeic acid Natural products OC(=O)C=CC1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-UHFFFAOYSA-N 0.000 description 1
- 239000008358 core component Substances 0.000 description 1
- 238000005536 corrosion prevention Methods 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical group P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
- 238000010494 dissociation reaction Methods 0.000 description 1
- 230000005593 dissociations Effects 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 235000021271 drinking Nutrition 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 210000004392 genitalia Anatomy 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229940037467 helicobacter pylori Drugs 0.000 description 1
- 239000012676 herbal extract Substances 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229910017053 inorganic salt Inorganic materials 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 239000007928 intraperitoneal injection Substances 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L magnesium chloride Substances [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 1
- 229910001629 magnesium chloride Inorganic materials 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 238000009629 microbiological culture Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000003607 modifier Substances 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000033116 oxidation-reduction process Effects 0.000 description 1
- 238000010979 pH adjustment Methods 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 201000001245 periodontitis Diseases 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000004260 plant-type cell wall biogenesis Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 239000003223 protective agent Substances 0.000 description 1
- 230000006916 protein interaction Effects 0.000 description 1
- 238000001243 protein synthesis Methods 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 235000019192 riboflavin Nutrition 0.000 description 1
- 239000002151 riboflavin Substances 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- -1 salt ion Chemical class 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 229930000044 secondary metabolite Natural products 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000001235 sensitizing effect Effects 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 230000009967 tasteless effect Effects 0.000 description 1
- 229940034610 toothpaste Drugs 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 241001148471 unidentified anaerobic bacterium Species 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a pet tartar removing liquid and a preparation method thereof, relates to the field of pet care liquids, and aims to solve the problem that tartar cannot be rapidly removed under the condition of reducing harm to pets in the prior art; the antibiotic can control the growth of bacteria in the oral cavity, the vitamin can improve the body immunity of pets, the boric acid can soften dental calculus, the dental calculus can be conveniently cleaned, and the pH regulator can regulate the overall pH value and prevent the pH value from being too low.
Description
Technical Field
The invention relates to the field of pet care solution, in particular to pet tartar removing solution and a preparation method thereof.
Background
In the process of feeding pets, as the pets can leave residues on teeth after eating, tartar, also called dental plaque, can appear on the teeth after a long time, and mainly causes harm to teeth and gum, namely the two most common diseases in the oral cavity: caries and periodontal disease.
Caries is commonly called "decayed tooth", and the term "worm" refers to bacteria in plaque, the plaque is firmly attached to tooth surface, the bacteria take in sugar in saliva, decompose sugar and produce acid, and the acid can destroy tooth and finally form cavity.
When plaque is brought close to the gums, the bacteria produce toxins and other harmful substances that irritate the gums (commonly referred to as "gums") and produce inflammation, i.e., gingivitis. If left uncontrolled, gingivitis may develop into irreversible periodontitis, causing destruction of the alveolar bone, which may eventually lead to loosening and loss of teeth.
Therefore, it is very important to perform dental care on pets to help the pets remove tartar, and a common tartar removal method is to help the pets brush teeth, but the brushing of the pets is time-consuming and labor-consuming, a great deal of time and energy are consumed, and therefore, the long-term periodic tooth cleaning is difficult.
Chinese patent CN201910896248.3 discloses a pet mouthwash and a preparation method thereof, and adopts the technical scheme that the pet mouthwash comprises the following raw materials in parts by weight: 4-9 parts of honeysuckle, 5-8 parts of sophora flower, 3-7 parts of centella, 3-7 parts of wild chrysanthemum flower, 2-4 parts of liquorice, 1-2 parts of salt, 1-2 parts of borax and 3-5 parts of hydrogen peroxide with the concentration of 1-5%; 0.5-0.8 part of citric acid, 0.1-0.3 part of sodium benzoate and 1-3 parts of tea polyphenol; the preparation method comprises the following steps: (1) taking 4-9 parts of honeysuckle, 5-8 parts of sophora flower, 3-7 parts of centella, 3-7 parts of wild chrysanthemum flower and 2-4 parts of liquorice according to parts by weight, adding water to enable the solid-liquid ratio to be 1:3-5, keeping the temperature for 1-2 hours at 90-100 ℃ after boiling, and filtering to obtain filtrate; (2) taking the filtrate prepared in the step (1), and adding 1-2 parts of salt, 1-2 parts of borax and 3-5 parts of 1-5% hydrogen peroxide; 0.5-0.8 part of citric acid, 0.1-0.3 part of sodium benzoate and 1-3 parts of tea polyphenol, fully stirring and mixing, and quantitatively subpackaging; the technical method adopts hydrogen peroxide to disinfect the oral cavity, but hydrogen peroxide is one of 3 carcinogens in a carcinogen list published by international cancer research institution of world health organization, can bring certain negative effects on pets, does not contain a pH adjusting component, can cause tooth decay when the pH is lower than 5, and can also cause damage to oral mucosa.
Disclosure of Invention
In view of the problems in the prior art, the invention discloses a pet tartar removing liquid, which adopts the technical scheme that the pet tartar removing liquid comprises the following components:
hypochlorous acid, polyphosphate, chlorogenic acid, plant extract, antibiotics, vitamins, boric acid and pH regulator.
Hypochlorous acid is oxyacid of chlorine element, has a chemical formula of HClO and a structural formula of H-O-Cl, wherein the valence of the chlorine element is + 1. It is present only in solution, its concentrated solution is yellow, its dilute solution is colourless, has a very pungent chlorine-like odour, and is extremely unstable, is a very weak acid, weaker than carbonic acid, and comparable to hydrogen-sulphuric acid. Hypochlorous acid also has a strong bleaching effect, and its salts can be used as bleaching agent and disinfectant. Hypochlorous acid is mainly used as a disinfectant, and is widely used for disinfecting polluted objects such as object surfaces, fabrics and the like, water, fruits, vegetables, eating and drinking utensils and the like. In addition to the above uses, hypochlorous acid can also be used for disinfection of indoor air, surfaces of secondary water supply facilities, hands, skin and mucous membranes.
The polyphosphate can inhibit the growth of microorganisms, thereby playing a role in antisepsis and bacteriostasis.
Chlorogenic acid which is an organic matter and has a chemical formula of C16H18O9Is one of the main antibacterial and antiviral effective pharmacological components of honeysuckle. The hemihydrate is needle crystals (water). And 110 ℃ to become an anhydrous compound. The solubility in water at 25 ℃ is 4%, and the solubility in hot water is higher. Is easily dissolved in ethanol and acetone, and is very slightly dissolved in ethyl acetate. Chlorogenic acid has a wide range of antibacterial effects, but can be inactivated by proteins in vivo. Similar to caffeic acid, the composition can improve central excitability of rat when administered orally or via intraperitoneal injection. Can increase the small intestinal peristalsis of rats and mice and the tension of the uterus of rats. Has choleretic effect and can promote bile secretion of rat. Has sensitizing effect on human, and can cause asthma and dermatitis after inhaling plant dust containing the product.
The plant extract is a substance extracted or processed from a plant (whole or a part of the plant) by adopting a proper solvent or method, and can be used in the pharmaceutical industry, the food industry, the daily chemical industry and other industries. There is a conceptual crossover between plant extracts and herbal extracts. Chinese plant extracts are mainly prepared from Chinese herbal medicines, so the domestic plant extracts can also be called Chinese medicine extracts to a certain extent.
Antibiotics refer to a class of secondary metabolites with anti-pathogen or other activities generated by microorganisms (including bacteria, fungi, actinomycetes) or higher animals and plants during life, and chemical substances capable of interfering with other life cell development functions. Antibiotics commonly used in clinical practice are extracts from microbial cultures and chemically synthesized or semisynthetic compounds. The bacteriostatic or bactericidal action of antibacterial agents such as antibiotics mainly aims at killing bacteria and human (or other animals and plants) without mechanisms, and comprises four action mechanisms, namely: inhibiting bacterial cell wall synthesis, enhancing bacterial cell membrane permeability, interfering with bacterial protein synthesis, and inhibiting bacterial nucleic acid replication transcription.
Vitamins are a class of trace organic substances that animals must obtain from food in order to maintain normal physiological functions, and play an important role in the growth, metabolism and development of animals. Vitamins are not involved in the formation of cells in the body, nor do they provide energy to the body.
Boric acid is an inorganic substance of formula H3BO3White powdery crystals or triclinic scaly crystals, smooth hand feeling and no odor. Dissolving in water, alcohol, glycerol, ethers and essential oil, and making the aqueous solution weakly acidic. Boric acid acts as a PH modifier, bacteriostatic preservative, where it softens calculus and aids in the cleaning of tartar.
The pH regulator is used for regulating the pH of the pet tartar removal liquid and preventing decayed teeth or oral mucosa injury caused by too low pH value.
As a preferred technical scheme of the invention, the weight of each component is as follows:
2-5 parts of hypochlorous acid, 3-10 parts of polyphosphate, 5-10 parts of chlorogenic acid, 10-35 parts of plant extract, 1-5 parts of antibiotic, 0.1-2 parts of vitamin, 2-3 parts of boric acid and 55-75 parts of pH regulator.
As a preferred technical scheme of the invention, the plant extract comprises persimmon tannin and rose extract.
Persimmon tannin is abundantly present in persimmons. Tannin, also called tannin, is a polyphenol polymer, and tannin contained in persimmons, called persimmon tannin, is a polyphenol polymer polymerized from catechol and the like, contains a plurality of ortho-position phenolic hydroxyl groups, so that the persimmon tannin has a plurality of functions, and has a plurality of functions of sun screening, moisture retention, wrinkle resistance, beauty treatment, corrosion prevention, sterilization, cardiovascular disease prevention, metal ion adsorption, protein interaction and the like.
The rose extract is a general name of various rose bud processing extracts. The rose extract can be used for preventing gingivitis and periodontal disease.
As a preferable technical scheme of the invention, the persimmon tannin accounts for 1-10 parts, and the rose extract accounts for 2-15 parts.
As a preferable technical scheme of the invention, the antibiotic is ornidazole.
Ornidazole, chemical name of 1- (3-chloro-2-hydroxypropyl) -2-methyl-5-nitroimidazole, is a 5-nitroimidazole antibiotic, and is used for treating various infectious diseases caused by sensitive anaerobic bacteria such as bacteroides fragilis, bacteroides dieldii, bacteroides ovatus, bacteroides thetaiotaomicron, bacteroides vulgatus, clostridium, eubacterium, peptococcus, helicobacter pylori, bacteroides melanoides, clostridium, CO2 vibrio bacteriovorus, gingival bacillus.
In a preferred embodiment of the present invention, the vitamin is vitamin B2.
Vitamin B2, also called riboflavin, is a component of the prosthetic group of enzymes in the body (the xanthase plays a hydrogen transfer role in biological oxidation-reduction), and when the flavoenzymes are deficient, the biological oxidation of the body is influenced, so that metabolism is disturbed, and the pathological changes of the flavoenzymes are mostly expressed as inflammation of the mouth, eyes and external genitalia parts, such as angular cheilitis, glossitis, conjunctivitis, scrotitis and the like.
In a preferred embodiment of the present invention, the pH adjuster comprises sodium bicarbonate and a concentrated salt buffer.
Sodium bicarbonate of formula NaHCO3It is an inorganic salt, white crystalline powder, odorless, tasteless and easily soluble in water. Slowly decomposing in moist air or hot air to generate carbon dioxide, and heating to 270 deg.C to completely decompose. When meeting acid, the acid is strongly decomposed to generate carbon dioxide; the sodium bicarbonate has alkalescence and can adjust the pH value.
Concentrated saline buffer is a phosphate buffered saline solution, generally acting as a solvent, which acts to solubilize the protective agent. It is a buffer solution which is most widely used in biochemical research, and the main component of the buffer solution is Na2HPO4、KH2PO4NaCl and KCl due to Na2HPO4And KH2PO4There is a second order dissociation, the buffered pH range is wide, and NaCl and KCl mainly function to increase the salt ion concentration. If necessary, the PBS can be supplemented with 1mmol/L CaCl2And 0.5mmol/L MgCl2To provide divalent cations.
In a preferable technical scheme of the invention, the sodium bicarbonate is 7-10 parts, and the concentrated salt buffer solution is 45-65 parts.
The invention also discloses a preparation method of the pet tartar removing liquid, which adopts the technical scheme that the preparation method comprises the following steps:
step 1, mixing hypochlorous acid, polyphosphate, chlorogenic acid, persimmon tannin, a rose extract, ornidazole, vitamin B2 and boric acid in proportion and uniformly stirring to obtain a mixture A;
step 2, detecting the pH value of the mixture A obtained in the step 1, adding sodium bicarbonate according to the obtained pH value, and adjusting the pH value to 6.4-7.5 to obtain a mixture B;
and 3, adding concentrated salt buffer solution into the mixture B obtained in the step 2.
The invention has the beneficial effects that: the invention adopts hypochlorous acid to disinfect the oral cavity, not only has good disinfection effect, but also can not bring about the potential safety hazard of carcinogenesis, the polyphosphate can inhibit the growth of bacteria and keep the oral cavity clean, and various plant extracts can resist gingivitis, inhibit the growth of bacteria and eliminate halitosis; the antibiotic can control the growth of bacteria in the oral cavity, the vitamin can improve the body immunity of pets, the boric acid can soften dental calculus, the dental calculus can be conveniently cleaned, and the pH regulator can regulate the overall pH value and prevent the pH value from being too low.
Furthermore, sodium bicarbonate in the pH regulator can regulate the pH value, and the concentrated salt buffer solution can regulate the salt balance and play a role in pH buffering.
Detailed Description
Example 1
The embodiment discloses a first implementation mode of the invention, and adopts the technical scheme that the invention comprises the following components:
hypochlorous acid, polyphosphate, chlorogenic acid, plant extract, antibiotics, vitamins, boric acid and pH regulator.
Hypochlorous acid can disinfect, polyphosphate, chlorogenic acid and antibiotics can resist bacteria and inhibit microbial growth, and boric acid can soften calculus.
As a preferred technical scheme of the invention, the weight of each component is as follows:
2 parts of hypochlorous acid, 3 parts of polyphosphate, 5 parts of chlorogenic acid, 10 parts of plant extract, 1 part of antibiotic, 0.1 part of vitamin, 2 parts of boric acid and 75 parts of pH regulator.
The proportion concentration is low, and the toothpaste is suitable for being used when dental calculus is light.
As a preferred technical scheme of the invention, the plant extract comprises persimmon tannin and rose extract.
The persimmon tannin and rose extract have antibacterial, antigingivitis, and halitosis removing effects.
As a preferred technical scheme of the invention, the persimmon tannin accounts for 1 part, and the rose extract accounts for 2 parts.
As a preferable technical scheme, the antibiotic is ornidazole, and the ornidazole can be used for treating gingival bacteroides.
In a preferred embodiment of the present invention, the vitamin is vitamin B2.
As a preferred technical scheme of the invention, the pH regulator comprises sodium bicarbonate and concentrated salt buffer solution; the sodium bicarbonate can make the tartar removal liquid alkaline, and the concentrated salt buffer solution can reduce the change value of the pH value after the preparation is finished.
In a preferred embodiment of the present invention, the sodium bicarbonate is 7 parts, and the concentrated salt buffer is 65 parts.
The invention also discloses a preparation method of the pet tartar removing liquid, which adopts the technical scheme that the preparation method comprises the following steps:
step 1, mixing hypochlorous acid, polyphosphate, chlorogenic acid, persimmon tannin, a rose extract, ornidazole, vitamin B2 and boric acid in proportion and uniformly stirring to obtain a mixture A; the mixture A is a main component mixture;
step 2, detecting the pH value of the mixture A obtained in the step 1, adding sodium bicarbonate according to the obtained pH value, and adjusting the pH value to 6.4-7.5 to obtain a mixture B; the mixture B is a component after pH adjustment;
and 3, adding concentrated salt buffer solution into the mixture B obtained in the step 2.
Example 2
The embodiment discloses a second implementation mode of the invention, and adopts the technical scheme that the invention comprises the following components:
hypochlorous acid, polyphosphate, chlorogenic acid, plant extract, antibiotics, vitamins, boric acid and pH regulator.
Hypochlorous acid can disinfect, polyphosphate, chlorogenic acid and antibiotics can resist bacteria and inhibit microbial growth, and boric acid can soften calculus.
As a preferred technical scheme of the invention, the weight of each component is as follows:
5 parts of hypochlorous acid, 10 parts of polyphosphate, 10 parts of chlorogenic acid, 35 parts of plant extract, 5 parts of antibiotic, 2 parts of vitamin, 3 parts of boric acid and 55 parts of pH regulator.
As a preferred technical scheme of the invention, the plant extract comprises persimmon tannin and rose extract.
As a preferable technical scheme of the invention, the persimmon tannin accounts for 10 parts, and the rose extract accounts for 15 parts.
As a preferable technical scheme of the invention, the antibiotic is ornidazole.
In a preferred embodiment of the present invention, the vitamin is vitamin B2.
As a preferred technical scheme of the invention, the pH regulator comprises sodium bicarbonate and concentrated salt buffer solution; the sodium bicarbonate can make the tartar removal liquid alkaline, and the concentrated salt buffer solution can reduce the change value of the pH value after the preparation is finished.
In a preferred embodiment of the present invention, the sodium bicarbonate is 10 parts, and the concentrated salt buffer is 45 parts.
The invention also discloses a preparation method of the pet tartar removing liquid, which adopts the technical scheme that the preparation method comprises the following steps:
step 1, mixing hypochlorous acid, polyphosphate, chlorogenic acid, persimmon tannin, a rose extract, ornidazole, vitamin B2 and boric acid in proportion and uniformly stirring to obtain a mixture A; this is the core component;
step 2, detecting the pH value of the mixture A obtained in the step 1, adding sodium bicarbonate according to the obtained pH value, and adjusting the pH value to 6.4-7.5 to obtain a mixture B; the pH value reaches the standard;
and 3, adding concentrated salt buffer solution into the mixture B obtained in the step 2.
Example 3
The third embodiment of the present invention is disclosed in this example, and adopts the technical scheme that the third embodiment of the present invention comprises the following components:
hypochlorous acid, polyphosphate, chlorogenic acid, plant extract, antibiotics, vitamins, boric acid and pH regulator.
As a preferred technical scheme of the invention, the weight of each component is as follows:
3.5 parts of hypochlorous acid, 6.5 parts of polyphosphate, 7.5 parts of chlorogenic acid, 22.5 parts of plant extract, 3 parts of antibiotic, 1 part of vitamin, 2.5 parts of boric acid and 65 parts of pH regulator.
As a preferred technical scheme of the invention, the plant extract comprises persimmon tannin and rose extract.
As a preferable technical scheme of the invention, the persimmon tannin comprises 5 parts, and the rose extract comprises 8 parts.
As a preferable technical scheme of the invention, the antibiotic is ornidazole.
In a preferred embodiment of the present invention, the vitamin is vitamin B2.
In a preferred embodiment of the present invention, the pH adjuster comprises sodium bicarbonate and a concentrated salt buffer.
In a preferred embodiment of the present invention, the sodium bicarbonate is 8 parts, and the concentrated salt buffer is 57 parts.
The invention also discloses a preparation method of the pet tartar removing liquid, which adopts the technical scheme that the preparation method comprises the following steps:
step 1, mixing hypochlorous acid, polyphosphate, chlorogenic acid, persimmon tannin, a rose extract, ornidazole, vitamin B2 and boric acid in proportion and uniformly stirring to obtain a mixture A;
step 2, detecting the pH value of the mixture A obtained in the step 1, adding sodium bicarbonate according to the obtained pH value, and adjusting the pH value to 6.4-7.5 to obtain a mixture B;
and 3, adding concentrated salt buffer solution into the mixture B obtained in the step 2.
Although the present invention has been described in detail with reference to the specific embodiments, the present invention is not limited to the above embodiments, and various changes and modifications without inventive changes may be made within the knowledge of those skilled in the art without departing from the spirit of the present invention.
Claims (9)
1. The pet tartar removal liquid is characterized by comprising the following components:
hypochlorous acid, polyphosphate, chlorogenic acid, plant extract, antibiotics, vitamins, boric acid and pH regulator.
2. The pet tartar removal liquid as defined in claim 1, wherein the pet tartar removal liquid comprises the following components in parts by weight:
2-5 parts of hypochlorous acid, 3-10 parts of polyphosphate, 5-10 parts of chlorogenic acid, 10-35 parts of plant extract, 1-5 parts of antibiotic, 0.1-2 parts of vitamin, 2-3 parts of boric acid and 55-75 parts of pH regulator.
3. A pet tartar removal fluid as defined in claim 2, further comprising: the plant extract comprises persimmon tannin and rose extract.
4. A pet tartar removal fluid as defined in claim 3, further comprising: the persimmon tannin accounts for 1-10 parts, and the rose extract accounts for 2-15 parts.
5. A pet tartar removal fluid as defined in claim 1, further comprising: the antibiotic is ornidazole.
6. A pet tartar removal fluid as defined in claim 1, further comprising: the vitamin is vitamin B2.
7. A pet tartar removal fluid as defined in claim 1, further comprising: the pH regulator comprises sodium bicarbonate and concentrated salt buffer solution.
8. A pet tartar removal fluid as defined in claim 7, further comprising: 7-10 parts of sodium bicarbonate and 45-65 parts of concentrated salt buffer solution.
9. A preparation method of pet tartar removal liquid is characterized by comprising the following steps:
step 1, mixing hypochlorous acid, polyphosphate, chlorogenic acid, persimmon tannin, a rose extract, ornidazole, vitamin B2 and boric acid in proportion and uniformly stirring to obtain a mixture A;
step 2, detecting the pH value of the mixture A obtained in the step 1, adding sodium bicarbonate according to the obtained pH value, and adjusting the pH value to 6.4-7.5 to obtain a mixture B;
and 3, adding concentrated salt buffer solution into the mixture B obtained in the step 2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111175516.6A CN113750011A (en) | 2021-10-09 | 2021-10-09 | Pet tartar removing liquid and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111175516.6A CN113750011A (en) | 2021-10-09 | 2021-10-09 | Pet tartar removing liquid and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113750011A true CN113750011A (en) | 2021-12-07 |
Family
ID=78798960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111175516.6A Pending CN113750011A (en) | 2021-10-09 | 2021-10-09 | Pet tartar removing liquid and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113750011A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114795993A (en) * | 2022-02-25 | 2022-07-29 | 上海弗艾柏生物科技有限公司 | Antibacterial and antiseptic composition for pet oral cleaning product and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109172745A (en) * | 2018-10-24 | 2019-01-11 | 南京海洛阿姆生物科技有限公司 | A kind of pet's oral cavity fungicide and preparation method thereof |
| CN112121105A (en) * | 2020-09-15 | 2020-12-25 | 长江大学 | Mouthwash spray for pets and preparation method thereof |
| CN112315842A (en) * | 2020-10-27 | 2021-02-05 | 杭州宠趣生物科技有限公司 | Dog and cat oral care spray containing lysozyme and preparation method thereof |
-
2021
- 2021-10-09 CN CN202111175516.6A patent/CN113750011A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109172745A (en) * | 2018-10-24 | 2019-01-11 | 南京海洛阿姆生物科技有限公司 | A kind of pet's oral cavity fungicide and preparation method thereof |
| CN112121105A (en) * | 2020-09-15 | 2020-12-25 | 长江大学 | Mouthwash spray for pets and preparation method thereof |
| CN112315842A (en) * | 2020-10-27 | 2021-02-05 | 杭州宠趣生物科技有限公司 | Dog and cat oral care spray containing lysozyme and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 李春 等: "不同牙膏抗牙石效果的比较", 《牙体牙髓牙周病学杂志》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114795993A (en) * | 2022-02-25 | 2022-07-29 | 上海弗艾柏生物科技有限公司 | Antibacterial and antiseptic composition for pet oral cleaning product and application thereof |
| CN114795993B (en) * | 2022-02-25 | 2024-03-19 | 上海弗艾柏生物科技有限公司 | Antibacterial and antiseptic composition for pet oral cleaning product and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20090269288A1 (en) | Black pearl toothpaste | |
| CN101321513A (en) | Vehicles for oral care with magnolia bark extract | |
| JPWO2008153077A1 (en) | Anti-norovirus agent and composition containing the same | |
| CN106924162A (en) | A kind of application of plant additive, bacteriostatic agent, oral care product and plant additive in oral care product is prepared | |
| US5137717A (en) | Cosmetic preparation having germicidal properties | |
| CN113750011A (en) | Pet tartar removing liquid and preparation method thereof | |
| CN108078806A (en) | Effective type removing abnormal flavor in oral cavity toothpaste | |
| AU2008275599B2 (en) | Composition and packaging method for animal dental care | |
| CN105832614B (en) | A kind of edible natural children's toothpaste and preparation method | |
| CN108434174A (en) | It is a kind of to be used to assist dental caries therapeutic and the mouth sprays and preparation method thereof of pre- anti-caries | |
| CN103599182A (en) | Traditional Chinese medicine composition and preparation method thereof, and oral cavity cleaning and nursing product and preparation method thereof | |
| CN108210385B (en) | A jelly-like collutory with effects of preventing dental caries, resisting bacteria, strengthening root and consolidating teeth | |
| CN116350614A (en) | Traditional Chinese medicine preparation for resisting caries pathogenic bacteria | |
| CN105213216B (en) | A kind of natural disaccharide antibacterial shield tooth gargle and preparation method thereof | |
| Dhakal et al. | Comparative antimicrobial efficacy study of different commercially available toothpaste in In-dia: An in vitro study | |
| CN106309740A (en) | Drug for cleaning oral cavities | |
| CN116019741A (en) | Plant essential oil and preparation method and application thereof | |
| KR100637653B1 (en) | Oral composition for inhibiting the halitosis | |
| CN107582737A (en) | A kind of compound chlorohexidene oral-cavity disinfectant and preparation method thereof | |
| Raj et al. | Herbal mouthwash. | |
| CN114668698A (en) | Plant ingredient mouthwash | |
| CN114209616A (en) | Gargle | |
| Wirata et al. | Decrease in the number of Streptococcus mutans and Staphylococcus aureus bacterial colonies after administration of sentul fruit peel extract gel (Sandoricum koetjape) in gingivitis model of white Wistar rats | |
| KR20080101954A (en) | Powder-type dentifrice composition contained silver particles | |
| EP0461105B1 (en) | Composition for prevention of plaque formation and plaque dependent diseases |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20211207 |
|
| RJ01 | Rejection of invention patent application after publication |