CN109172745A - A kind of pet's oral cavity fungicide and preparation method thereof - Google Patents

A kind of pet's oral cavity fungicide and preparation method thereof Download PDF

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Publication number
CN109172745A
CN109172745A CN201811247210.5A CN201811247210A CN109172745A CN 109172745 A CN109172745 A CN 109172745A CN 201811247210 A CN201811247210 A CN 201811247210A CN 109172745 A CN109172745 A CN 109172745A
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CN
China
Prior art keywords
parts
oral cavity
pet
sodium
extract
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Pending
Application number
CN201811247210.5A
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Chinese (zh)
Inventor
孙新波
曹正兵
曹国斌
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Nanjing Hero Eminem Biotechnology Co Ltd
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Nanjing Hero Eminem Biotechnology Co Ltd
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Priority to CN201811247210.5A priority Critical patent/CN109172745A/en
Publication of CN109172745A publication Critical patent/CN109172745A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8984Dendrobium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/22Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

The present invention provides a kind of pet's oral cavity fungicide and preparation method thereof.Pet's oral cavity fungicide of the invention, it is characterized in that: in parts by weight including sodium chlorite 2-7 parts, 3-8 parts of sodium dichloro cyanurate, 10-20 parts of sodium bisulfate, 5-15 parts of sodium bicarbonate, 1-3 parts of boric acid, 2-5 parts of hypochlorous acid, 5-15 parts of Herba Dendrobii extract, 5-15 parts of dandelion extract, 100 parts of distilled water.The present invention can effectively kill the initiating agent of all kinds of mouth diseases such as fungi, bacterium, mycoplasma, virus, protozoon class biology in pet's oral cavity, and inhibit its growth, change the original environment conducive to bacteria breed procreation of cavity interior, prevent various oral cavity common diseases, removing abnormal flavor in oral cavity is removed, oral inflammation is made to be controlled and eradicate.

Description

A kind of pet's oral cavity fungicide and preparation method thereof
Technical field:
The present invention relates to a kind of pet's oral cavity fungicide and preparation method thereof, belong to chemical technology field.
Background technique:
Pet oral hygiene not only makes pet loss of appetite itself, pain, more also can be by contacting bacterial infection To the mankind at one's side, particularly against the infant and old man under power, for pet, they do not understand if telling master The pain of people oneself causes illness increasingly severe, loss of appetite etc..In the annual dead pet in China, 45% is mouth Chamber problem causes, and therefore, the hygienic issues of pet's oral cavity are particularly important.
There are many traditional conditioning liquids at present such as: physiological saline, sodium bicarbonate mouth shield liquid, hydrogenperoxide steam generator or some Medical product such as chlorohexidene, metronidazole etc..But normal saline solution is used to carry out dentilave nursing, it can after water price evaporation Hypertonic solution is formed, hypochlorous acid is largely put aside on oral cavity mucous membrane tissue, and dry, mucosa hemorrhage etc. are caused;And hydrogen peroxide is molten Its comparison of ingredients of the conditioning liquids such as liquid is single, and major function is exactly cleaning and wet oral cavity, may only realize suppression to a certain extent Bacterium, bactericidal effect have been difficult to meet nursing demand.
Summary of the invention:
It, can be effective the purpose of the present invention is providing a kind of pet's oral cavity fungicide and preparation method thereof in view of the above problems The initiating agent of all kinds of mouth diseases such as fungi, bacterium, mycoplasma, virus, the protozoon class biology in pet's oral cavity is killed, and is pressed down Its growth is made, changes the original environment conducive to bacteria breed procreation of cavity interior, prevents various oral cavity common diseases, remove mouth Cavity foreign flavor makes oral inflammation be controlled and eradicate.
Above-mentioned purpose is realized by following technical scheme:
Pet's oral cavity fungicide, in parts by weight include sodium chlorite 2-7 parts, 3-8 parts of sodium dichloro cyanurate, sodium bisulfate 10-20 parts, 5-15 parts of sodium bicarbonate, 1-3 parts of boric acid, 2-5 parts of hypochlorous acid, 5-15 parts of Herba Dendrobii extract, dandelion extract 5- 15 parts, 100 parts of distilled water.
The pet's oral cavity fungicide, in parts by weight include 5 parts of sodium chlorite, 6 parts of sodium dichloro cyanurate, sulfuric acid 14 parts of hydrogen sodium, 11 parts of sodium bicarbonate, 2 parts of boric acid, 4 parts of hypochlorous acid, 10 parts of Herba Dendrobii extract, 10 parts of dandelion extract, distillation 100 parts of water.
The preparation method of above-mentioned pet's oral cavity fungicide, this method comprises the following steps:
(1) Herba Dendrobii extract is prepared;
(2) dandelion extract is prepared;
(3) the middle dandelion extract 5-15 prepared of the Herba Dendrobii extract 5-15 parts by weight prepared in step (1), step (2) is taken 2-7 parts of parts by weight, sodium chlorite, 3-8 parts of sodium dichloro cyanurate, 10-20 parts of sodium bisulfate, 5-15 parts of sodium bicarbonate, boric acid It 1-3 parts, 2-5 parts of hypochlorous acid, is added in the water of 100 parts by weight, is thoroughly mixed uniformly.
The preparation method of the pet's oral cavity fungicide, the preparation method of Herba Dendrobii extract as described in step (1) is: After dendrobium nobile is cleaned up, the water of its 10 times of weight is added, small burn to the amount of liquid is the water being added after boiling 20%-25%, filter liquor.
The preparation method of the pet's oral cavity fungicide, the preparation method of dandelion extract described in step (2) It is that after cleaning up dandelion medicinal material, the water of its 10 times of weight is added, it is small after boiling to burn to the amount of liquid to be added Water 15%-20%, filter liquor.
The utility model has the advantages that
1. due to dendrobium nobile nourishing yin and lessening fire, clearing heat and promoting fluid effect.To fire excess from yin deficiency, flaring up of deficient fire, the raw sore of the erosion of mucous membrane in the oral cavity, year after year not More, often recurrence, it is helpful.And dandelion has extensive pharmacological activity, especially antibacterial action more significant, has wide The antibacterial action of spectrum all has certain biocidal efficacies for corynebacterium diphtheriae, Pseudomonas aeruginosa, shigella dysenteriae, typhoid bacillus.This Invention proportion can be killed effectively and be doted on sodium chlorite, sodium dichloro cyanurate, sodium bisulfate, sodium bicarbonate, boric acid, hypochlorous acid The initiating agent of all kinds of mouth diseases such as the intraoral fungi of object, bacterium, mycoplasma, virus, protozoon class biology, and inhibit its life It is long, change the original environment conducive to bacteria breed procreation of cavity interior, prevent various oral cavity common diseases, removal oral cavity is different Taste makes oral inflammation be controlled and eradicate.
Specific embodiment:
Embodiment 1:
Pet's oral cavity fungicide, in parts by weight including 5 parts of sodium chlorite, 6 parts of sodium dichloro cyanurate, 14 parts of sodium bisulfate, 11 parts of sodium bicarbonate, 2 parts of boric acid, 4 parts of hypochlorous acid, 10 parts of Herba Dendrobii extract, 10 parts of dandelion extract, 100 parts of distilled water.
The preparation method of above-mentioned pet's oral cavity fungicide, this method comprises the following steps:
(1) Herba Dendrobii extract is prepared;
(2) dandelion extract is prepared;
(3) middle 10 weight of dandelion extract prepared of 10 parts by weight of Herba Dendrobii extract prepared in step (1), step (2) is taken Part, 5 parts of sodium chlorite, 6 parts of sodium dichloro cyanurate, 14 parts of sodium bisulfate, 11 parts of sodium bicarbonate, 2 parts of boric acid, 4 parts of hypochlorous acid, It is added in the water of 100 parts by weight, is thoroughly mixed uniformly.
The preparation method of the pet's oral cavity fungicide, the preparation method of Herba Dendrobii extract as described in step (1) is: After dendrobium nobile is cleaned up, the water of its 10 times of weight is added, small burn to the amount of liquid is the water being added after boiling 20%-25%, filter liquor.
The preparation method of the pet's oral cavity fungicide, the preparation method of dandelion extract described in step (2) It is that after cleaning up dandelion medicinal material, the water of its 10 times of weight is added, it is small after boiling to burn to the amount of liquid to be added Water 15%-20%, filter liquor.
Embodiment 2:
The present embodiment difference from example 1 is that, pet's oral cavity fungicide described in the present embodiment, in parts by weight Including 2 parts of sodium chlorite, 8 parts of sodium dichloro cyanurate, 10 parts of sodium bisulfate, 15 parts of sodium bicarbonate, 1 part of boric acid, hypochlorous acid 5 Part, 5 parts of Herba Dendrobii extract, 15 parts of dandelion extract, 100 parts of distilled water.
Embodiment 3:
The present embodiment difference from example 1 is that, pet's oral cavity fungicide described in the present embodiment, in parts by weight Including 7 parts of sodium chlorite, 3 parts of sodium dichloro cyanurate, 20 parts of sodium bisulfate, 5 parts of sodium bicarbonate, 3 parts of boric acid, 2 parts of hypochlorous acid, 15 parts of Herba Dendrobii extract, 5 parts of dandelion extract, 100 parts of distilled water.
The above is only highly preferred embodiment of the present invention, the method for the present invention includes but be not limited to the above embodiments, the present invention Unaccomplished matter, belong to the common knowledge of those skilled in the art.

Claims (5)

1. a kind of pet's oral cavity fungicide, it is characterized in that: in parts by weight include sodium chlorite 2-7 parts, sodium dichloro cyanurate 3-8 parts, 10-20 parts of sodium bisulfate, 5-15 parts of sodium bicarbonate, 1-3 parts of boric acid, 2-5 parts of hypochlorous acid, 5-15 parts of Herba Dendrobii extract, 5-15 parts of dandelion extract, 100 parts of distilled water.
2. pet's oral cavity fungicide according to claim 1, it is characterized in that: in parts by weight including 5 parts of sodium chlorite, two 6 parts of symclosene sodium, 14 parts of sodium bisulfate, 11 parts of sodium bicarbonate, 2 parts of boric acid, 4 parts of hypochlorous acid, 10 parts of Herba Dendrobii extract, Pu 10 parts of public English extract, 100 parts of distilled water.
3. a kind of preparation method of pet's oral cavity fungicide, it is characterized in that: this method comprises the following steps:
(1) Herba Dendrobii extract is prepared;
(2) dandelion extract is prepared;
(3) the middle dandelion extract 5-15 prepared of the Herba Dendrobii extract 5-15 parts by weight prepared in step (1), step (2) is taken 2-7 parts of parts by weight, sodium chlorite, 3-8 parts of sodium dichloro cyanurate, 10-20 parts of sodium bisulfate, 5-15 parts of sodium bicarbonate, boric acid It 1-3 parts, 2-5 parts of hypochlorous acid, is added in the water of 100 parts by weight, is thoroughly mixed uniformly.
4. the preparation method of pet's oral cavity fungicide according to claim 3, it is characterized in that: stone as described in step (1) The preparation method of dry measure used in former times extract is: after dendrobium nobile is cleaned up, the water of its 10 times of weight is added, it is small after boiling to burn to liquid The amount of body is the 20%-25% for the water being added, filter liquor.
5. the preparation method of pet's oral cavity fungicide according to claim 3, it is characterized in that: Pu described in step (2) The preparation method of public English extract is that after cleaning up dandelion medicinal material, the water of its 10 times of weight is added, small after boiling It burns to the 15%-20% for the water that the amount of liquid is addition, filter liquor.
CN201811247210.5A 2018-10-24 2018-10-24 A kind of pet's oral cavity fungicide and preparation method thereof Pending CN109172745A (en)

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Application Number Priority Date Filing Date Title
CN201811247210.5A CN109172745A (en) 2018-10-24 2018-10-24 A kind of pet's oral cavity fungicide and preparation method thereof

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113750011A (en) * 2021-10-09 2021-12-07 研维科技(上海)有限公司 Pet tartar removing liquid and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103230356A (en) * 2013-05-07 2013-08-07 贵州省赤水市金钗石斛产业开发有限公司 Dendrobium nobile toothpaste
CN103876992A (en) * 2012-12-23 2014-06-25 吕艳 Swelling and inflammation diminishing mouthwash
CN104127340A (en) * 2014-07-23 2014-11-05 浙江森宇实业有限公司 Dendrobium officinale toothpaste and preparation method
CN106994132A (en) * 2016-11-19 2017-08-01 湖南云康共享生物环保有限公司 A kind of oral cavity disinfection sanitizer

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103876992A (en) * 2012-12-23 2014-06-25 吕艳 Swelling and inflammation diminishing mouthwash
CN103230356A (en) * 2013-05-07 2013-08-07 贵州省赤水市金钗石斛产业开发有限公司 Dendrobium nobile toothpaste
CN104127340A (en) * 2014-07-23 2014-11-05 浙江森宇实业有限公司 Dendrobium officinale toothpaste and preparation method
CN106994132A (en) * 2016-11-19 2017-08-01 湖南云康共享生物环保有限公司 A kind of oral cavity disinfection sanitizer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113750011A (en) * 2021-10-09 2021-12-07 研维科技(上海)有限公司 Pet tartar removing liquid and preparation method thereof

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Application publication date: 20190111

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