CN113693958A - Glabridin mask and preparation method thereof - Google Patents
Glabridin mask and preparation method thereof Download PDFInfo
- Publication number
- CN113693958A CN113693958A CN202011069710.1A CN202011069710A CN113693958A CN 113693958 A CN113693958 A CN 113693958A CN 202011069710 A CN202011069710 A CN 202011069710A CN 113693958 A CN113693958 A CN 113693958A
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- CN
- China
- Prior art keywords
- extract
- glabridin
- glycyrrhiza glabra
- solution
- mask
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- LBQIJVLKGVZRIW-ZDUSSCGKSA-N glabridin Chemical compound C1([C@H]2CC3=CC=C4OC(C=CC4=C3OC2)(C)C)=CC=C(O)C=C1O LBQIJVLKGVZRIW-ZDUSSCGKSA-N 0.000 title claims abstract description 35
- 229940093767 glabridin Drugs 0.000 title claims abstract description 35
- PMPYOYXFIHXBJI-ZDUSSCGKSA-N glabridin Natural products C1([C@H]2CC=3C=CC4=C(C=3OC2)CCC(O4)(C)C)=CC=C(O)C=C1O PMPYOYXFIHXBJI-ZDUSSCGKSA-N 0.000 title claims abstract description 35
- LBQIJVLKGVZRIW-UHFFFAOYSA-N glabridine Natural products C1OC2=C3C=CC(C)(C)OC3=CC=C2CC1C1=CC=C(O)C=C1O LBQIJVLKGVZRIW-UHFFFAOYSA-N 0.000 title claims abstract description 35
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 244000303040 Glycyrrhiza glabra Species 0.000 claims abstract description 37
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 37
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 32
- 244000270673 Pelargonium graveolens Species 0.000 claims abstract description 28
- 235000017927 Pelargonium graveolens Nutrition 0.000 claims abstract description 28
- -1 polydimethylsiloxane Polymers 0.000 claims abstract description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 16
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims abstract description 12
- QRYRORQUOLYVBU-VBKZILBWSA-N Carnosic acid Natural products CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 claims abstract description 11
- 108010087806 Carnosine Proteins 0.000 claims abstract description 11
- CQOVPNPJLQNMDC-UHFFFAOYSA-N N-beta-alanyl-L-histidine Natural products NCCC(=O)NC(C(O)=O)CC1=CN=CN1 CQOVPNPJLQNMDC-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 11
- 229940044199 carnosine Drugs 0.000 claims abstract description 11
- CQOVPNPJLQNMDC-ZETCQYMHSA-N carnosine Chemical compound [NH3+]CCC(=O)N[C@H](C([O-])=O)CC1=CNC=N1 CQOVPNPJLQNMDC-ZETCQYMHSA-N 0.000 claims abstract description 11
- PDYOTPOJFZAOIS-UHFFFAOYSA-N decanoic acid;2,2-dimethylpropane-1,3-diol;octanoic acid Chemical compound OCC(C)(C)CO.CCCCCCCC(O)=O.CCCCCCCCCC(O)=O PDYOTPOJFZAOIS-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000004205 dimethyl polysiloxane Substances 0.000 claims abstract description 11
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims abstract description 11
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 11
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 11
- 229920001285 xanthan gum Polymers 0.000 claims abstract description 11
- 239000000230 xanthan gum Substances 0.000 claims abstract description 11
- 229940082509 xanthan gum Drugs 0.000 claims abstract description 11
- 235000010493 xanthan gum Nutrition 0.000 claims abstract description 11
- 210000002969 egg yolk Anatomy 0.000 claims abstract description 7
- 239000003906 humectant Substances 0.000 claims abstract description 7
- 235000005152 nicotinamide Nutrition 0.000 claims abstract description 6
- 229960003966 nicotinamide Drugs 0.000 claims abstract description 6
- 239000011570 nicotinamide Substances 0.000 claims abstract description 6
- 238000000034 method Methods 0.000 claims abstract description 4
- 239000000243 solution Substances 0.000 claims description 33
- 238000003756 stirring Methods 0.000 claims description 28
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 26
- 244000234609 Portulaca oleracea Species 0.000 claims description 26
- 235000001855 Portulaca oleracea Nutrition 0.000 claims description 26
- 238000002156 mixing Methods 0.000 claims description 25
- 244000144927 Aloe barbadensis Species 0.000 claims description 20
- 235000002961 Aloe barbadensis Nutrition 0.000 claims description 20
- 235000011399 aloe vera Nutrition 0.000 claims description 20
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 16
- 244000245214 Mentha canadensis Species 0.000 claims description 15
- 240000005250 Chrysanthemum indicum Species 0.000 claims description 12
- 235000018959 Chrysanthemum indicum Nutrition 0.000 claims description 12
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical group CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 10
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 10
- 235000018978 Mentha arvensis Nutrition 0.000 claims description 10
- 235000016278 Mentha canadensis Nutrition 0.000 claims description 10
- 229920002125 Sokalan® Polymers 0.000 claims description 10
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 10
- 229960001631 carbomer Drugs 0.000 claims description 10
- 238000011049 filling Methods 0.000 claims description 10
- 235000010445 lecithin Nutrition 0.000 claims description 10
- 239000000787 lecithin Substances 0.000 claims description 10
- 229940067606 lecithin Drugs 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 10
- 238000005303 weighing Methods 0.000 claims description 10
- 241000246044 Sophora flavescens Species 0.000 claims description 9
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical group CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 9
- 235000001878 Mentha haplocalyx Nutrition 0.000 claims description 5
- 241000219784 Sophora Species 0.000 claims description 5
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 5
- 239000011259 mixed solution Substances 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims description 4
- 241001026287 Chrysanthellum indicum Species 0.000 claims description 3
- 240000008632 Cota tinctoria Species 0.000 claims description 3
- 102000002322 Egg Proteins Human genes 0.000 claims description 3
- 108010000912 Egg Proteins Proteins 0.000 claims description 3
- 235000006679 Mentha X verticillata Nutrition 0.000 claims description 3
- 235000002899 Mentha suaveolens Nutrition 0.000 claims description 3
- 235000001636 Mentha x rotundifolia Nutrition 0.000 claims description 3
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 3
- 230000010933 acylation Effects 0.000 claims description 3
- 238000005917 acylation reaction Methods 0.000 claims description 3
- 235000013345 egg yolk Nutrition 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 230000017105 transposition Effects 0.000 claims description 3
- 238000000605 extraction Methods 0.000 claims description 2
- 238000010298 pulverizing process Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 14
- 230000002087 whitening effect Effects 0.000 abstract description 7
- 102000004190 Enzymes Human genes 0.000 abstract description 6
- 108090000790 Enzymes Proteins 0.000 abstract description 6
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 abstract description 6
- 206010014970 Ephelides Diseases 0.000 abstract description 4
- 208000003351 Melanosis Diseases 0.000 abstract description 4
- 230000009286 beneficial effect Effects 0.000 abstract description 4
- 241000894006 Bacteria Species 0.000 abstract description 3
- 206010013786 Dry skin Diseases 0.000 abstract description 3
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 abstract description 3
- 230000003064 anti-oxidating effect Effects 0.000 abstract description 3
- 230000004054 inflammatory process Effects 0.000 abstract description 3
- 230000008569 process Effects 0.000 abstract description 3
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 abstract description 3
- 206010061218 Inflammation Diseases 0.000 abstract description 2
- 230000008901 benefit Effects 0.000 abstract description 2
- 238000011161 development Methods 0.000 abstract description 2
- 230000001737 promoting effect Effects 0.000 abstract description 2
- 235000011187 glycerol Nutrition 0.000 description 8
- 230000003796 beauty Effects 0.000 description 5
- 230000001815 facial effect Effects 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 235000007866 Chamaemelum nobile Nutrition 0.000 description 2
- 244000042664 Matricaria chamomilla Species 0.000 description 2
- 235000007232 Matricaria chamomilla Nutrition 0.000 description 2
- 244000246386 Mentha pulegium Species 0.000 description 2
- 235000016257 Mentha pulegium Nutrition 0.000 description 2
- 235000004357 Mentha x piperita Nutrition 0.000 description 2
- 235000001050 hortel pimenta Nutrition 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical group CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000037380 skin damage Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a glabridin mask and a preparation method thereof, wherein the glabridin mask comprises the following components in percentage by mass: water: 78% -86%, glycerol: 3% -6% of humectant: 4% -6%, xanthan gum: 0.08% -0.18%, polydimethylsiloxane: 0.5% -1.5%, neopentyl glycol dicaprylate/dicaprate: 1% -4%, sodium hyaluronate: 0.25% -0.45%, nicotinamide: 0.6% -1.5%, yolk: 0.05% -0.15%, GLYCYRRHIZA GLABRA (GLYCYRRHIZA GLABRA) extract: 0.1% -0.3%, carnosine: 0.15% -0.35%, PELARGONIUM GRAVEOLENS (PELARGONIUM GRAVEOLENS) extract: 0.1% -0.3%, the beneficial effects of the invention are: the glabridin is set as a main component, can penetrate into the skin and keep high activity, has the performances of whitening and high-efficiency antioxidation, can effectively inhibit the activity of various enzymes in the melanin generation process, particularly inhibit the activity of tyrosine enzyme, simultaneously has the effects of preventing skin roughness, resisting inflammation, removing freckles and resisting bacteria, can meet the market demand, is also beneficial to promoting the regional development of the glabridin with rich resources, and generates great economic benefit.
Description
Technical Field
The invention relates to the technical field of masks, in particular to a glabridin mask and a preparation method thereof.
Background
The beauty, for the nature of people, people develop a plurality of beauty products for protecting and beautifying skin, which can delay the aging process of skin and keep beautiful appearance as long as possible, and the beauty products in the market are not good and uniform, some have good effect on skin maintenance, but some have the characteristics of whitening and high-efficiency antioxidation because the raw materials contain a plurality of chemical substances and contain no harmful ingredients to human body, which easily causes adverse reaction, even the beauty products can not protect skin after being used, but can bring skin damage, and the glabridin can go deep into the skin and keep high activity, can effectively inhibit the activity of a plurality of enzymes in the melanin generation process, particularly inhibit the activity of tyrosine enzyme, and simultaneously has the effects of preventing skin roughness and inflammation, removing freckles and resisting bacteria, and the glabridin is a whitening component with good curative effect and comprehensive function, the glabridin has good oxidation resistance and whitening effect, is called whitening gold, and has been widely accepted in the industry, but no beauty cosmetics containing the glabridin can simultaneously have the effects of whitening and removing freckles in the market at present.
Disclosure of Invention
The invention aims to provide a glabridin mask and a preparation method thereof, and aims to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme that the glabridin mask comprises the following components in percentage by mass: water: 78% -86%, glycerol: 3% -6% of humectant: 4% -6%, xanthan gum: 0.08% -0.18%, polydimethylsiloxane: 0.5% -1.5%, neopentyl glycol dicaprylate/dicaprate: 1% -4%, sodium hyaluronate: 0.25% -0.45%, nicotinamide: 0.6% -1.5%, yolk: 0.05% -0.15%, GLYCYRRHIZA GLABRA (GLYCYRRHIZA GLABRA) extract: 0.1% -0.3%, carnosine: 0.15% -0.35%, PELARGONIUM GRAVEOLENS (PELARGONIUM GRAVEOLENS) extract: 0.1% -0.3%, ALOE vera (ALOE BARBADENSIS) extract: 0.2% -0.4%, purslane (Portulaca OLERACEA) extract: 0.1% -0.3%, extract of golden chamomile (Chrysanthellum INDICUM): 0.15% -0.35%, mint (MENTHA ARVENSIS) leaf extract: 0.2% -0.5%, radix sophorae flavescentis (SOPHORA ANGUSTIFOLIA) root extract: 0.1% -0.3%, C20-22 alcohol: 0.05-0.25%, p-hydroxyacetophenone: 0.3% -0.7%, 1, 2-hexylene alcohol: 0.3% -0.6%, carbomer: 0.08% -0.14%, triethanolamine: 0.05 to 0.15 percent.
Preferably, the humectant is butylene glycol.
Preferably, the egg yolk is lecithin.
Preferably, the GLYCYRRHIZA GLABRA (GLYCYRRHIZA GLABRA) extract is obtained by extracting GLYCYRRHIZA GLABRA with ethanol assisted ultrasonic wave.
Preferably, the ratio of the GLYCYRRHIZA GLABRA (GLYCYRRHIZA GLABRA) extract, the PELARGONIUM GRAVEOLENS (PELARGONIUM GRAVEOLENS) extract and the purslane (PORTULACA OLERACEA) extract is 1:1: 1.
Preferably, the sophora flavescens extract is a filtrate obtained by crushing dry sophora flavescens roots to obtain sophora flavescens powder, then adding the sophora flavescens powder into an extracting solution, stirring and extracting the mixture, and filtering the mixture.
Preferably, the p-hydroxyacetophenone is prepared by using phenol as a raw material and carrying out acylation and transposition.
A preparation method of a glabridin mask comprises the following steps:
s1, preparing a solution I: weighing nicotinamide, lecithin, Glycyrrhiza GLABRA (Glycyrrhiza GLABRA) extract, carnosine, Pelargonium GRAVEOLENS (Pelargonium GRAVEOLENS) extract, Aloe BARBADENSIS (Aloe BARBADENSIS) extract, Portulaca OLERACEA (Portulaca OLERACEA) extract, Chrysanthemum INDICUM (Chrysanthemum INDICUM) extract, Mentha haplocalyx (MENTHA ARVENSIS) leaf extract and radix Sophorae Flavescentis (Sophora gustifolia) root extract according to formula proportion, adding into partial water, heating and stirring to completely dissolve;
s2, preparing a solution II: weighing glycerol, butanediol, xanthan gum, polydimethylsiloxane, neopentyl glycol dicaprylate/dicaprate and sodium hyaluronate according to the formula proportion, adding the materials together, uniformly mixing, adding C20-22 alcohol, and uniformly mixing;
s3, preparing a solution III: according to the formula proportion, adding the p-hydroxyacetophenone, the 1, 2-hexylene alcohol, the carbomer and the triethanolamine into a part of water, and stirring until the materials are completely dissolved;
s4, mixing and stirring: adding the solution I into the solution II, stirring for 40 minutes, adding the solution III, and continuing stirring for 15 minutes;
s5, blending and filling: and (4) uniformly blending the mixed solution obtained in the step (4) to form a sticky glabridin mask, and then filling.
Compared with the prior art, the invention has the beneficial effects that:
the glabridin is set as a main component, can penetrate into the skin and keep high activity, has the performances of whitening and high-efficiency antioxidation, can effectively inhibit the activity of various enzymes in the melanin generation process, particularly inhibit the activity of tyrosine enzyme, simultaneously has the effects of preventing skin roughness, resisting inflammation, removing freckles and resisting bacteria, can meet the market demand, is also beneficial to promoting the regional development of the glabridin with rich resources, and generates great economic benefit.
Detailed Description
The invention provides a technical scheme that: a glabridin facial mask comprises the following components in percentage by mass: water: 78% -86%, glycerol: 3% -6% of humectant: 4% -6%, xanthan gum: 0.08% -0.18%, polydimethylsiloxane: 0.5% -1.5%, neopentyl glycol dicaprylate/dicaprate: 1% -4%, sodium hyaluronate: 0.25% -0.45%, nicotinamide: 0.6% -1.5%, yolk: 0.05% -0.15%, GLYCYRRHIZA GLABRA (GLYCYRRHIZA GLABRA) extract: 0.1% -0.3%, carnosine: 0.15% -0.35%, PELARGONIUM GRAVEOLENS (PELARGONIUM GRAVEOLENS) extract: 0.1% -0.3%, ALOE vera (ALOE BARBADENSIS) extract: 0.2% -0.4%, purslane (Portulaca OLERACEA) extract: 0.1% -0.3%, extract of golden chamomile (Chrysanthellum INDICUM): 0.15% -0.35%, mint (MENTHA ARVENSIS) leaf extract: 0.2% -0.5%, radix sophorae flavescentis (SOPHORA ANGUSTIFOLIA) root extract: 0.1% -0.3%, C20-22 alcohol: 0.05-0.25%, p-hydroxyacetophenone: 0.3% -0.7%, 1, 2-hexylene alcohol: 0.3% -0.6%, carbomer: 0.08% -0.14%, triethanolamine: 0.05 to 0.15 percent.
Wherein the humectant is butanediol.
Wherein the egg yolk is lecithin.
Wherein the Glycyrrhiza GLABRA (Glycyrrhiza GLABRA) extract is obtained by extracting Glycyrrhiza GLABRA with ethanol assisted ultrasonic wave.
Wherein the ratio of Glycyrrhiza GLABRA (Glycyrrhiza GLABRA) extract, Pelargonium GRAVEOLENS (Pelargonium GRAVEOLENS) extract and Portulaca OLERACEA (Portulaca OLERACEA) extract is 1:1: 1.
Wherein the radix Sophorae Flavescentis extract is obtained by pulverizing dried radix Sophorae Flavescentis to obtain radix Sophorae Flavescentis powder, adding into the extractive solution, stirring for extraction, and filtering to obtain filtrate.
Wherein, the p-hydroxyacetophenone is prepared by taking phenol as a raw material and carrying out acylation and transposition.
A preparation method of a glabridin mask comprises the following steps:
s1, preparing a solution I: weighing nicotinamide, lecithin, Glycyrrhiza GLABRA (Glycyrrhiza GLABRA) extract, carnosine, Pelargonium GRAVEOLENS (Pelargonium GRAVEOLENS) extract, Aloe BARBADENSIS (Aloe BARBADENSIS) extract, Portulaca OLERACEA (Portulaca OLERACEA) extract, Chrysanthemum INDICUM (Chrysanthemum INDICUM) extract, Mentha haplocalyx (MENTHA ARVENSIS) leaf extract and radix Sophorae Flavescentis (Sophora gustifolia) root extract according to formula proportion, adding into partial water, heating and stirring to completely dissolve;
s2, preparing a solution II: weighing glycerol, butanediol, xanthan gum, polydimethylsiloxane, neopentyl glycol dicaprylate/dicaprate and sodium hyaluronate according to the formula proportion, adding the materials together, uniformly mixing, adding C20-22 alcohol, and uniformly mixing;
s3, preparing a solution III: according to the formula proportion, adding the p-hydroxyacetophenone, the 1, 2-hexylene alcohol, the carbomer and the triethanolamine into a part of water, and stirring until the materials are completely dissolved;
s4, mixing and stirring: adding the solution I into the solution II, stirring for 40 minutes, adding the solution III, and continuing stirring for 15 minutes;
s5, blending and filling: and (4) uniformly blending the mixed solution obtained in the step (4) to form a sticky glabridin mask, and then filling.
Example 1, a glabridin facial mask, which comprises the following components in percentage by mass: water: 82.15%, glycerol: 5% and butanediol: 4%, xanthan gum: 0.1%, polydimethylsiloxane: 1%, neopentyl glycol dicaprylate/dicaprate: 2%, sodium hyaluronate: 0.3%, nicotinamide: 1%, lecithin: 1%, GLYCYRRHIZA GLABRA (GLYCYRRHIZA GLABRA) extract: 0.2%, carnosine: 0.3%, PELARGONIUM GRAVEOLENS (PELARGONIUM GRAVEOLENS) extract: 0.2%, ALOE vera (ALOE BARBADENSIS) extract: 0.25%, purslane (PORTULACA OLERACEA) extract: 0.2%, extract of chamomile (Chrysanthemum INDICUM): 0.3%, peppermint (MENTHA ARVENSIS) leaf extract: 0.4%, radix sophorae flavescentis (SOPHORA ANGUSTIFOLIA) root extract: 0.1%, C20-22 alcohol: 0.15%, p-hydroxyacetophenone: 0.5%, 1, 2-hexylene alcohol: 0.6%, carbomer: 0.1%, triethanolamine: 0.15 percent.
A preparation method of a glabridin mask comprises the following steps:
s1, preparing a solution I: weighing nicotinamide, lecithin, Glycyrrhiza GLABRA (Glycyrrhiza GLABRA) extract, carnosine, Pelargonium GRAVEOLENS (Pelargonium GRAVEOLENS) extract, Aloe BARBADENSIS (Aloe BARBADENSIS) extract, Portulaca OLERACEA (Portulaca OLERACEA) extract, Chrysanthemum INDICUM (Chrysanthemum INDICUM) extract, Mentha haplocalyx (MENTHA ARVENSIS) leaf extract and radix Sophorae Flavescentis (Sophora gustifolia) root extract according to formula proportion, adding into partial water, heating and stirring to completely dissolve;
s2, preparing a solution II: weighing glycerol, butanediol, xanthan gum, polydimethylsiloxane, neopentyl glycol dicaprylate/dicaprate and sodium hyaluronate according to the formula proportion, adding the materials together, uniformly mixing, adding C20-22 alcohol, and uniformly mixing;
s3, preparing a solution III: according to the formula proportion, adding the p-hydroxyacetophenone, the 1, 2-hexylene alcohol, the carbomer and the triethanolamine into a part of water, and stirring until the materials are completely dissolved;
s4, mixing and stirring: adding the solution I into the solution II, stirring for 40 minutes, adding the solution III, and continuing stirring for 15 minutes;
s5, blending and filling: and (4) uniformly blending the mixed solution obtained in the step (4) to form a sticky glabridin mask, and then filling.
Embodiment 2, a glabridin facial mask, which comprises the following components in percentage by mass: water: 80%, glycerin: 5% and butanediol: 6% of xanthan gum: 0.1%, polydimethylsiloxane: 1%, neopentyl glycol dicaprylate/dicaprate: 2%, sodium hyaluronate: 0.45%, nicotinamide: 1.3%, lecithin: 1%, GLYCYRRHIZA GLABRA (GLYCYRRHIZA GLABRA) extract: 0.1%, carnosine: 0.2%, PELARGONIUM GRAVEOLENS (PELARGONIUM GRAVEOLENS) extract: 0.1%, ALOE vera (ALOE BARBADENSIS) extract: 0.2%, purslane (PORTULACA OLERACEA) extract: 0.1%, extract of chamomile (Chrysanthemum INDICUM): 0.35%, peppermint (MENTHA ARVENSIS) leaf extract: 0.5%, radix sophorae flavescentis (SOPHORA ANGUSTIFOLIA) root extract: 0.1%, C20-22 alcohol: 0.15%, p-hydroxyacetophenone: 0.6%, 1, 2-hexylene alcohol: 0.5%, carbomer: 0.1%, triethanolamine: 0.15 percent.
A preparation method of a glabridin mask comprises the following steps:
s1, preparing a solution I: weighing nicotinamide, lecithin, Glycyrrhiza GLABRA (Glycyrrhiza GLABRA) extract, carnosine, Pelargonium GRAVEOLENS (Pelargonium GRAVEOLENS) extract, Aloe BARBADENSIS (Aloe BARBADENSIS) extract, Portulaca OLERACEA (Portulaca OLERACEA) extract, Chrysanthemum INDICUM (Chrysanthemum INDICUM) extract, Mentha haplocalyx (MENTHA ARVENSIS) leaf extract and radix Sophorae Flavescentis (Sophora gustifolia) root extract according to formula proportion, adding into partial water, heating and stirring to completely dissolve;
s2, preparing a solution II: weighing glycerol, butanediol, xanthan gum, polydimethylsiloxane, neopentyl glycol dicaprylate/dicaprate and sodium hyaluronate according to the formula proportion, adding the materials together, uniformly mixing, adding C20-22 alcohol, and uniformly mixing;
s3, preparing a solution III: according to the formula proportion, adding the p-hydroxyacetophenone, the 1, 2-hexylene alcohol, the carbomer and the triethanolamine into a part of water, and stirring until the materials are completely dissolved;
s4, mixing and stirring: adding the solution I into the solution II, stirring for 40 minutes, adding the solution III, and continuing stirring for 15 minutes;
s5, blending and filling: and (4) uniformly blending the mixed solution obtained in the step (4) to form a sticky glabridin mask, and then filling.
In the present invention, unless otherwise expressly specified or limited, the terms "mounted," "disposed," "connected," "secured," "screwed" and the like are to be construed broadly, e.g., as meaning fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; the terms may be directly connected or indirectly connected through an intermediate, and may be communication between two elements or interaction relationship between two elements, unless otherwise specifically limited, and the specific meaning of the terms in the present invention will be understood by those skilled in the art according to specific situations.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. The glabridin mask is characterized by comprising the following components in percentage by mass: water: 78% -86%, glycerol: 3% -6% of humectant: 4% -6%, xanthan gum: 0.08% -0.18%, polydimethylsiloxane: 0.5% -1.5%, neopentyl glycol dicaprylate/dicaprate: 1% -4%, sodium hyaluronate: 0.25% -0.45%, nicotinamide: 0.6% -1.5%, yolk: 0.05% -0.15%, GLYCYRRHIZA GLABRA (GLYCYRRHIZA GLABRA) extract: 0.1% -0.3%, carnosine: 0.15% -0.35%, PELARGONIUM GRAVEOLENS (PELARGONIUM GRAVEOLENS) extract: 0.1% -0.3%, ALOE vera (ALOE BARBADENSIS) extract: 0.2% -0.4%, purslane (Portulaca OLERACEA) extract: 0.1% -0.3%, extract of golden chamomile (Chrysanthellum INDICUM): 0.15% -0.35%, mint (MENTHA ARVENSIS) leaf extract: 0.2% -0.5%, radix sophorae flavescentis (SOPHORA ANGUSTIFOLIA) root extract: 0.1% -0.3%, C20-22 alcohol: 0.05-0.25%, p-hydroxyacetophenone: 0.3% -0.7%, 1, 2-hexylene alcohol: 0.3% -0.6%, carbomer: 0.08% -0.14%, triethanolamine: 0.05 to 0.15 percent.
2. The glabridin mask according to claim 1, wherein: the humectant is butanediol.
3. The glabridin mask according to claim 1, wherein: the egg yolk is lecithin.
4. The glabridin mask according to claim 1, wherein: the Glycyrrhiza GLABRA (Glycyrrhiza GLABRA) extract is obtained by extracting Glycyrrhiza GLABRA with ethanol assisted ultrasonic wave.
5. The glabridin mask according to claim 1, wherein: the ratio of Glycyrrhiza GLABRA (Glycyrrhiza GLABRA) extract, Pelargonium GRAVEOLENS (Pelargonium GRAVEOLENS) extract and Portulaca OLERACEA (Portulaca OLERACEA) extract is 1:1: 1.
6. The glabridin mask according to claim 1, wherein: the radix Sophorae Flavescentis extract is prepared by pulverizing dried radix Sophorae Flavescentis to obtain radix Sophorae Flavescentis powder, adding into the extractive solution, stirring for extraction, and filtering to obtain filtrate.
7. The glabridin mask according to claim 1, wherein: the p-hydroxyacetophenone is prepared from phenol through acylation and transposition.
8. A preparation method of a glabridin mask is characterized by comprising the following steps: the method comprises the following steps:
s1, preparing a solution I: weighing nicotinamide, lecithin, Glycyrrhiza GLABRA (Glycyrrhiza GLABRA) extract, carnosine, Pelargonium GRAVEOLENS (Pelargonium GRAVEOLENS) extract, Aloe BARBADENSIS (Aloe BARBADENSIS) extract, Portulaca OLERACEA (Portulaca OLERACEA) extract, Chrysanthemum INDICUM (Chrysanthemum INDICUM) extract, Mentha haplocalyx (MENTHA ARVENSIS) leaf extract and radix Sophorae Flavescentis (Sophora gustifolia) root extract according to formula proportion, adding into partial water, heating and stirring to completely dissolve;
s2, preparing a solution II: weighing glycerol, butanediol, xanthan gum, polydimethylsiloxane, neopentyl glycol dicaprylate/dicaprate and sodium hyaluronate according to the formula proportion, adding the materials together, uniformly mixing, adding C20-22 alcohol, and uniformly mixing;
s3, preparing a solution III: according to the formula proportion, adding the p-hydroxyacetophenone, the 1, 2-hexylene alcohol, the carbomer and the triethanolamine into a part of water, and stirring until the materials are completely dissolved;
s4, mixing and stirring: adding the solution I into the solution II, stirring for 40 minutes, adding the solution III, and continuing stirring for 15 minutes;
s5, blending and filling: and (4) uniformly blending the mixed solution obtained in the step (4) to form a sticky glabridin mask, and then filling.
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| CN116327617A (en) * | 2023-04-11 | 2023-06-27 | 广州恒芳生物科技有限公司 | Whitening and moisturizing essence composition and preparation method thereof |
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| CN110169945A (en) * | 2019-06-15 | 2019-08-27 | 苏州市熹朵化妆品有限公司 | A kind of essence facial mask and preparation method thereof |
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| CN110169945A (en) * | 2019-06-15 | 2019-08-27 | 苏州市熹朵化妆品有限公司 | A kind of essence facial mask and preparation method thereof |
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| CN116327617A (en) * | 2023-04-11 | 2023-06-27 | 广州恒芳生物科技有限公司 | Whitening and moisturizing essence composition and preparation method thereof |
| CN116327617B (en) * | 2023-04-11 | 2024-04-19 | 广州恒芳生物科技有限公司 | Whitening and moisturizing essence composition and preparation method thereof |
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