CN1136861C - 'Lifeiqing' capsule for treating pulmonary tuberculosis - Google Patents
'Lifeiqing' capsule for treating pulmonary tuberculosis Download PDFInfo
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- CN1136861C CN1136861C CNB001052322A CN00105232A CN1136861C CN 1136861 C CN1136861 C CN 1136861C CN B001052322 A CNB001052322 A CN B001052322A CN 00105232 A CN00105232 A CN 00105232A CN 1136861 C CN1136861 C CN 1136861C
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Abstract
The present invention relates to a 'Lifeiqing' capsule for treating pulmonary tuberculosis, which has the advantages of convenience for taking, no toxic or side effect and obvious curative effect. The capsule is filled with Chinese herbal medicine powder composition, and the Chinese herbal medicines comprise bugle, rehmannia roots and a formulation comprises components of the following Chinese herbal medicines added one by one: lilyturf roots, lily, tendrilled fritillary bulbs, unprocessed licorice roots, scrophularia roots, balloonflower roots, white peony roots, prepared rhizome of rehmannia and Chinese angelica roots. In the formulation, the white peony roots, the prepared rhizome of rehmannia and the Chinese angelica roots can also be replaced by the combination of pleione rhizome, trichosanthis, stemona roots, bletilla tuber and scutellaria roots. The capsule can be used for treating pulmonary tuberculosis, pulmonary carbuncle, pulmonary abscess, pneumonia, laryngopharyngitis, bronchitis, serious cough, etc.
Description
The invention belongs to the Chinese herbal and crude drugs preparations of treatment pulmonary tuberculosis.
The pulmonary tuberculosis traditional Chinese medical science also claims " pulmonary tuberculosis ", is to have the weak disease of communicable chronic expendable, and becoming thin gradually etc. with cough, hemoptysis, hectic fever, night sweat four big cardinal symptoms and health is its feature.Sick position is mainly at lung, and dirty relevant with spleen, kidney etc.A tree name relevant department is observed, and pulmonary tuberculosis is on the rise in recent years, and China's tuberculosis is popular also quite severe, and existing 3.3 hundred million people in the whole nation infect tulase, and the active tuberculosis patient reaches 5,900,000 people, accounts for world patient's 1/4 (1996 years statistics).
At present, the Western medicine commonly used of state's internal therapy pulmonary tuberculosis has streptomycin, isoniazid, rifampicin, rifandin, ethambutol, pyrazinamide, sodium aminosalicylate, defend the lung spy, defend that lung is peaceful, Dipasic etc., the caused ear poison reaction that the toxic and side effects of these antituberculosis drugses has, make auditory dysesthesia, tinnitus, dizzy, hematuria, oliguria, visual deterioration, anaphylactic shock, as streptomycin etc.; The reaction that has has hepatic insufficiency, the medicine liver, and peripheral neuritis, idol has the maincenter disorder, hypomnesis, toxic maincenter psychosis and encephalopathy etc. are as isoniazid etc.; The reaction that has has gastrointestinal upset, nausea and vomiting, diarrhea, pseudomembranous enteritis, thrombocytopenia, erythra, hemolytic anemia, renal dysfunction, influenza sample syndrome, liver poison, but teratogenesis etc. also, as rifampicin etc.; The untoward reaction that has has based on ball backsight net neuritis, comprises visual disorder even blind, leukopenia, as ethambutol etc.; Have except that the intestines and stomach side effect, can cause that also blood system changes, fainting from fear also can appear in heavy dose, the epileptic outbreak, as defends the lung spy.In a word, anti-in the market consumptive disease Western medicine all exists the different toxic and side effects of degree.The traditional Chinese medical science is generally advocated nourishing YIN and moistening the lung to the treatment pulmonary tuberculosis, Gu the Jinjian spleen, the rule of kidney tonifying training unit, adopt classic famous prescription of the traditional Chinese medical science such as moonlight ball respectively, baihe gujin decoction, the Radix Gentianae Marcrophyllae Carapax Trionycis looses, fidelity soup, one-tenth sides such as SHENLING BAISHU SAN plus-minus is executed and is controlled, and certain curative effect is arranged.
The object of the present invention is to provide a kind of having no side effect, evident in efficacy, the Chinese herbal and crude drugs preparations of the treatment pulmonary tuberculosis of taking convenience.
The capsular technical solution of Lifeiqing that the present invention treats pulmonary tuberculosis is to be filled with Chinese herbal medicine powder process in the softgel shell, and its special character is that described Chinese herbal medicine is Herba Ajugae, the Radix Rehmanniae, Radix Ophiopogonis, Bulbus Lilii, Bulbus Fritillariae Uninbracteatae, Radix Glycyrrhizae, Radix Scrophulariae, Radix Platycodonis, Pseudobulbus Cremastrae Seu Pleiones, Fructus Trichosanthis, the Radix Stemonae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Scutellariae.
Herba Ajugae claims " Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) ", " japanese bugle herb " again.
Described Chinese herbal medicine powder process can be that corresponding Chinese herbal medicine (doing) is fried in shallow oil the concentrated branch powder process of anhydrating of juice.
Capsule of the present invention mixes canned softgel shell by described Chinese herbal medicine powder process and forms.The parts by weight collocation of described powder process is:
Herba Ajugae powder/Radix Rehmanniae powder/Radix Ophiopogonis powder/Bulbus Lilii powder/Bulbus Fritillariae Uninbracteatae powder/Radix Glycyrrhizae powder/Radix Scrophulariae powder/balloonflower powder/Pseudobulbus Cremastrae Seu Pleiones powder/Fructus Trichosanthis powder/Radix Stemonae powder/Pseudobulbus Bletillae (Rhizoma Bletillae) powder/Radix Scutellariae powder is (2～14)/(3～10)/(2～9)/(3～6)/(2～8)/(1～6)/(2～7)/(1～6)/(2～7)/(2～9)/(2～7)/(3～7)/(2～9).
Capsule of the present invention has refreshing and detoxicating, nourishing YIN and moistening the lung, the sterilization of eliminating the phlegm, detumescence hemostasis waits effect, can be exclusively used in to treat all types of (containing Drug resistance) pulmonary tuberculosis, lung abscess, lung abscess, pulmonary carcinoma in earlier stage, pneumonia, pharyngolaryngitis, bronchitis, bronchiectasis, serious coughs etc. cause that to pulmonary infection body temperature low grade fever hyperpyrexia does not move back for a long time, to seriousness influenza health have a fever one week body temperature not down, unique cooling function is arranged.
Capsule of the present invention, with the content of 0.5g (powder is heavy)/grain, dose can be 6/time, 3 times/day, every month 1 course of treatment, or 10/time, 2 times/day, every month 1 course of treatment.
Capsule of the present invention, routine pulmonary tuberculosis patient examination clothes surplus 120, effective percentage reaches 98%, and cure rate reaches 95%, and has no side effect.
Capsule of the present invention shows through on probation, and the existing Western medicine of pulmonary tuberculosis human 6～9 months is curable, just can cure in 1～3 month with this capsule; Some critically ill patient can't be cured with existing Western medicine in 1～3 year, promptly cured in 6～9 months with this capsule.
Have 2 routine patients invalid through Shanghai lung section hospital treatment, 1 routine patient fails to respond to any medical treatment through tumour hospital of Beijing lung section, and 1 routine patient fails to respond to any medical treatment through Shanxi Yun Cheng traditional Chinese medical science tuberculosis hospital, after these 4 patients through taking this capsule 6～9 months, all give healing.
Control example 1: patient Zhou Fule, the man, 37 years old, live belt East Road, Leqing, Zhejiang city No. 340, because of fall ill on January 30th, 1996 to Leqing city the People's Hospital's hospitalization, admission number 403007 is taken the photograph sheet (sheet number 152278) indication (writing down this slightly) through X ray, is diagnosed as: 1, tuberculous cavity formation on two lung TB (tuberculosis) companions.2, left side hydropneumothorax, lung compression 30%.Treat 1 wheat harvesting period through this institute and do not obtain obvious improvement.Leqing city institute of traditional Chinese medicine hospitalization is changeed on March 15th, 1996 in the back, admission number 4429, and bed label 242, the same substantially through Chest X-rays, not have obviously and improve, all the other symptoms are the same, and diagnosis is the same, through continuing treatment on April 4, this, because of the family financial situation difficulty is independently left hospital.Still have cough when leaving hospital, the sputum mixed with blood silk.After this patient introduce through other people and take capsule of the present invention, body temperature still has 38.5 ℃ of fluctuations before the clothes, when companion's cough, out of breath, night sweat outbreak is arranged, it is serious to become thin, body weight is 40kg only.Through taking one week of this capsule, patient's subjective symptoms is known and is subtracted, and heat is moved back, and cough alleviates, and is in high spirits, and stomach is received amelioration, the tired improvement, and night sweat is few, continues and takes this capsule continuously 7 months, and all cards are all healed, and follow up a case by regular visits to so far recurrence, participate in rural labor already.
Control example 2: patient Wang Rongsheng, man, 28 years old, live Hou Suo township, Leqing, Zhejiang city, because of the hectic diagnosis and treatment of being in hospital to the People's Hospital, Leqing city, take the photograph the sheet inspection through X ray in JIUYUE in 1996 28 days, sheet number 163337 (sheet shows record, and these omit), being examined is " right upper lung TB companion cavity forms ".The patient is through taking this capsule after 2 months, go to this institute to do the Chest X-rays inspection again on November 26th, 96, sheet numbers 165830, sheet shows that symptom is clearly better, advises its continuous this capsule of clothes 1 wheat harvesting period, all diseases are all removed, weight increase 20kg, in high spirits, whole body training sense is strong, go to Shenyang to do manual work at the beginning of 96 years 12 months, through visiting not recurrence again in 2 years.
Control example 3: patient Liu Xian, the man 28 years old, lives horizontal village, Liu Shi lake, Leqing city, the Chest X-rays of 1 Nikkei Leqing November in 1997 city institute of traditional Chinese medicine is checked, sheet numbers 35044 (sheet show record this slightly) is examined and is pulmonary tuberculosis, through taking this capsule after 3 months, go this institute's check on February 28th, 1998, the state of an illness takes a favorable turn, and fully recovers after 3 months through continuous this capsule of clothes, visits and does not have recurrence in 2 years.
Control example 4: patient Yang Yongfang, woman, 22 years old, Jinsha County, Guizhou Province peace Lip river village people, it is surplus to suffer from infiltrative pulmonary tuberculosis III type 1 year, shows at Qianxi County institute of traditional Chinese medicine Chest X-rays sheet on June 24th, 97 (sheet number 14051): two lung marking disorders, two lungs are seen most stigma dot-hatched, and the minority calcification point is arranged, heart diaphragm (-).Through this capsule for treating 3 months, in the check in 12, of 97 on Decembers, sheet shows: two lungs showed no obvious abnormalities X line shade, and the podiod size and form is in normal range, and diaphram is not different from.Final diagnosis impression: " two lung heart diaphragms are normal ".
Control example 5: patient Xu Lidan, the woman, 26 years old, Leqing, Zhejiang city Xiang Yang people from town, because of cough, hectic fever, night sweat, weakness, come this institute (the present invention, applicant place " the bright pulmonary tuberculosis Study of Medicinal Herbs in Leqing city institute ") to seek medical advice on November 21st, 96, the first visit impression is lung TB, taking the photograph sheet (sheet number 165691) through the X of the People's Hospital, Leqing city line shows: " two lung fields are mottled, the increase in density shadow of rope strip, clear border; the right lung point is seen～2.0 * 2.0cm size cavity in addition; aneroid is flat, and surplus lung heart diaphragm is not different from ".This capsule of patient's oral administration is the above-mentioned symptom elimination after 28 days.
Control example 6: patient Liu Yanshun, the man, 65 years old, live Liu Zhai village, horizontal township, lake, Leqing city, in March, 95 is serious because of pulmonary tuberculosis, go the hospitalize of Shanghai lung section, twice lung excisions are about 1/4, leave hospital after sb.'s illness took a favorable turn, but less than 1 year at the beginning of 96 recurrence very more preceding, go the Shanghai further consultation again, after this annual recurrence 1～2 time.In June, 98 occurs serious emphysema and be difficult to breathe, rescue through the People's Hospital, Leqing city, burrow in chest and help breathing, hospitalization was not healed in more than 40 day, independently left hospital because of financial difficulties, and it is serious to breathe after leaving hospital, myasthenia of limbs, and the sticking productive cough of normal obstruction is not come out in the larynx.After after taking this capsule two weeks, the fruit that takes effect greatly breathes normally, resistance expectorant no longer in the larynx, and sticking expectorant reduces day by day, and appetite increases by 30%, and extremity are strong, through taking this capsule continuously after 9 months, all diseases are eliminated, and take the photograph the sheet inspection through willow city hospital and show that pulmonary tuberculosis does not exist.
Control example 7: patient Chen Xufang, the man, 53 years old, the Leqing white elephant cadre of industrial and commercial administrative bureau, hectic take upon somebody's introduction this capsule after 1 month disease eliminate, through First People's Hospital, Wenzhou City, the People's Hospital, Leqing city and Leqing tuberculosis prevention and treatment check confirmation TB and eliminate.
Control example 8: the Leqing white elephant property tax young cadre of institute Xu is precious to admire, and hectic is lived the People's Hospital, Leqing city and treated more than 20 day hemoptysis and do not heal, and takes this capsule upon somebody's introduction 4 days, and hemoptysis is promptly ended, and serve on this capsule and fully recovers after 2 months.
Control example 9: patient Zhang Weiguang, the man, 25 years old, Leqing Da Jing people from town, seriously live in sea market lung section hospitalize 4 month because of TB in May, 98, spent more than 60,000 yuan of healing of medical fee and left hospital.The back was less than recurrence in 10 months, and the 1000cc that once spits blood promptly goes Shanghai Pulmonary Hospital treatment, and haematemesis stops, but was drug resistant pulmonary tuberculosis through bacterial analysis, the hospitalization two weeks, and the Shanghai doctor says and can't treat.The whole foxtail millet shapes of patient's two lungs, go Ningbo Ci Cheng hospitalize two weeks invalid completely through ward mate's introduction, change Wenzhou hospitals of traditional Chinese and western medicine treatment two weeks again still to no effect, after patient location hospital doctor introduce, took this capsule 10 days, respond well, continue this capsule of clothes and per 2 months bat CT once, clap the X sheet every month and show that once symptom is clearly better, patient says " progressive day by day ".
Control example 10: patient Xue Huacheng, the man, 50 years old, live Hongqiao town, Leqing city, hectic III type, two lung patch shapes, edge blurry takes a turn for the better more than 5 years in the hospitalize of Beijing lung section, back 2 years with Beijing Hospital's preparation cough consumptive disease loose Chinese medicine powder take 2 years also ineffective, clothes " safe force rate holder " combination " safe force rate holder " injection treatment several months has no effect again, fully recovers after 9 months after this capsule is taken in Liu of the People's Hospital, Leqing city surname doctor introduction.
On the secret prescription handed down in the family from generation to generation basis, with reference to other traditional Chinese medical science allusion quotation mat, research was repeatedly screened and optimum organization, makes patent medicine, controls 47 routine all kinds of consumptives through clinical examination, all takes the photograph sheet through the X line and confirms that treatment is succeedd from beginning in 1998 in the present invention.The inventor submitted a report asking for the Leqing Municipal Commission of Science and Technology in 1997, get permission to set up " the bright pulmonary tuberculosis Study of Medicinal Herbs in Leqing city institute " through audit.
The present invention's capsule, examination such as toxicity, susceptibility, clinical efficacy, check, what have does, the WKG working that has, the plan that has is done.
The present invention's capsule, in JIUYUE, 1998 is done toxicity test through Zhejiang Medical university pharmacology teaching and research room, and the result is " the Lifeiqing capsule is equivalent to clinical in 120 times of dosage to mice maximum tolerated dose＞18g/kg body weight ".
The present invention's capsule, the susceptibility check is done by tuberculosis prevention ﹠ care inst, 18 Nikkei Hangzhou August in 1999, the result is: concentration is human-like for the standard that Ministry of Public Health tuberculosis research center is provided of 10mg/ml, cattle type sensitive strain kills 1/3, concentration 100mg/ml, 250mg/ml's, described bacterial strain is all killed.
Because the present invention's capsule has no side effect, good bactericidal property and existing remarkable curative effect, August in 1999, No. 115 certification agreement of medicine letter (1999) word " carry out the clinical preliminary test of 20 routine pulmonary tuberculosis cases in the tuberculosis prevention ﹠ care inst, Hangzhou, the clinical preliminary test scheme is responsible to define and is implemented by the tuberculosis prevention ﹠ care inst, Hangzhou " defended in Zhejiang Province bureau of drug policy ﹠ administration on the 30th Zhejiang.
The present invention's capsule, taking convenience has no side effect, and sterilizing power is strong, and is remarkable to the pulmonary tuberculosis therapeutic effect.
The specific embodiment of the present invention that table 1 is classified as.Numeral is corresponding Chinese herbal medicine powder process weight portion in the table.Every embodiment makes capsule of the present invention for the mixed powder of the Chinese herbal medicine powder process of corresponding weight portion is canned.
Table 1
| The name of an article (powder process) | Example 1 | Example 2 | Example 3 | Example 4 | Example 5 | Example 6 | Example 7 | Example 8 | Example 9 | Example 10 | Example 11 | Example 12 | Example 13 | Example 14 |
| Herba Ajugae | 3.5 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 3 | 2 |
| The Radix Rehmanniae | 6 | 5 | 4 | 5 | 3 | 7 | 4 | 9 | 8 | 5 | 6 | 10 | 8 | 7 |
| Radix Ophiopogonis | 5 | 6 | 3 | 5 | 4 | 6 | 5 | 4 | 3 | 2 | 4 | 7 | 9 | 8 |
| Bulbus Lilii | 3 | 4 | 3 | 3 | 3 | 2 | 4 | 5 | 5 | 3 | 6 | 5 | 4 | 3 |
| Bulbus Fritillariae Uninbracteatae | 3 | 3 | 2 | 3 | 2 | 3 | 2 | 3 | 4 | 6 | 7 | 8 | 5 | 4 |
| Radix Glycyrrhizae | 3 | 2 | 3 | 2 | 3 | 1 | 3 | 4 | 2 | 5 | 1 | 4 | 3 | 6 |
| Radix Scrophulariae | 2 | 3 | 2 | 6 | 2 | 4 | 2 | 3 | 7 | 4 | 4 | 3 | 5 | 2 |
| Radix Platycodonis | 2 | 2 | 1 | 2 | 3 | 5 | 1 | 2 | 4 | 3 | 6 | 4 | 3 | 1 |
| Pseudobulbus Cremastrae Seu Pleiones | 3 | 4 | 2 | 5 | 7 | 6 | 2 | 4 | 6 | 5 | 3 | 5 | 4 | 4 |
| Fructus Trichosanthis | 4 | 4 | 5 | 3 | 2 | 4 | 3 | 4 | 3 | 6 | 3 | 7 | 9 | 8 |
| The Radix Stemonae | 3 | 2 | 4 | 2 | 3 | 5 | 4 | 3 | 7 | 4 | 5 | 4 | 3 | 7 |
| The Pseudobulbus Bletillae (Rhizoma Bletillae) | 4 | 3 | 4 | 3 | 5 | 6 | 3 | 4 | 2 | 7 | 3 | 5 | 7 | 6 |
| Radix Scutellariae | 3 | 4 | 3 | 4 | 4 | 3 | 4 | 5 | 2 | 8 | 3 | 7 | 8 | 9 |
Claims (1)
1, the Lifeiqing capsule of treatment pulmonary tuberculosis, be filled with Chinese herbal medicine powder process in the softgel shell, the described Chinese herbal medicine powder process of its feature is counted with parts by weight: Herba Ajugae powder/Radix Rehmanniae powder/Radix Ophiopogonis powder/Bulbus Lilii powder/Bulbus Fritillariae Uninbracteatae powder/Radix Glycyrrhizae powder/Radix Scrophulariae powder/balloonflower powder/Pseudobulbus Cremastrae Seu Pleiones powder/Fructus Trichosanthis powder/Radix Stemonae powder/Pseudobulbus Bletillae (Rhizoma Bletillae) powder/Radix Scutellariae powder is the mixed dust formulation of (2～14)/(3～10)/(2～9)/(3～6)/(2～8)/(1～6)/(2～7)/(1～6)/(2～7)/(2～9)/(2～7)/(3～7)/(2～9).
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001052322A CN1136861C (en) | 2000-04-07 | 2000-04-07 | 'Lifeiqing' capsule for treating pulmonary tuberculosis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001052322A CN1136861C (en) | 2000-04-07 | 2000-04-07 | 'Lifeiqing' capsule for treating pulmonary tuberculosis |
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| Publication Number | Publication Date |
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| CN1317317A CN1317317A (en) | 2001-10-17 |
| CN1136861C true CN1136861C (en) | 2004-02-04 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB001052322A Expired - Fee Related CN1136861C (en) | 2000-04-07 | 2000-04-07 | 'Lifeiqing' capsule for treating pulmonary tuberculosis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN100376283C (en) * | 2005-11-17 | 2008-03-26 | 山东润华药业有限公司 | Chinese medicinal composition for treating tuberculosis and its preparation method |
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| CN103007026A (en) * | 2011-09-27 | 2013-04-03 | 天津中敖生物科技有限公司 | Chinese medicinal composition with function of moistening lung for removing phlegm and preparation method thereof |
| CN103181565A (en) * | 2013-03-07 | 2013-07-03 | 苟春虎 | PM2.5-preventing capsule for clearing away lung toxicant and protecting lungs |
| CN103301318B (en) * | 2013-06-24 | 2014-11-05 | 周秀玲 | Traditional Chinese medicine for treating suppurative pneumonia |
| CN103341103B (en) * | 2013-07-10 | 2015-01-21 | 华菊 | Traditional Chinese medicine composition for treating pulmonary tuberculosis and preparation method thereof |
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| CN111265635A (en) * | 2020-02-20 | 2020-06-12 | 杨德胜 | Traditional Chinese medicine preparation for preventing and treating coronavirus pneumonia |
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2000
- 2000-04-07 CN CNB001052322A patent/CN1136861C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100376283C (en) * | 2005-11-17 | 2008-03-26 | 山东润华药业有限公司 | Chinese medicinal composition for treating tuberculosis and its preparation method |
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