CN104096053A - Medicine composition for treating infantile pneumonia - Google Patents
Medicine composition for treating infantile pneumonia Download PDFInfo
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- CN104096053A CN104096053A CN201410379992.3A CN201410379992A CN104096053A CN 104096053 A CN104096053 A CN 104096053A CN 201410379992 A CN201410379992 A CN 201410379992A CN 104096053 A CN104096053 A CN 104096053A
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- 239000003814 drug Substances 0.000 title claims abstract description 28
- 206010035664 Pneumonia Diseases 0.000 title claims abstract description 22
- 229940079593 drug Drugs 0.000 title claims abstract description 16
- 239000000203 mixture Substances 0.000 title abstract description 5
- 210000000582 semen Anatomy 0.000 claims abstract description 13
- 239000008194 pharmaceutical composition Substances 0.000 claims description 14
- 241000628997 Flos Species 0.000 claims description 6
- 241000018014 Liparis japonica Species 0.000 claims description 6
- 241000244155 Taenia Species 0.000 claims description 6
- 239000003826 tablet Substances 0.000 claims description 6
- 235000005903 Dioscorea Nutrition 0.000 claims description 3
- 241000234273 Dioscorea Species 0.000 claims description 3
- 235000000504 Dioscorea villosa Nutrition 0.000 claims description 3
- 241000207929 Scutellaria Species 0.000 claims description 3
- 235000004879 dioscorea Nutrition 0.000 claims description 3
- 239000007919 dispersible tablet Substances 0.000 claims description 2
- 239000002674 ointment Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 5
- 244000291564 Allium cepa Species 0.000 abstract 1
- 235000002732 Allium cepa var. cepa Nutrition 0.000 abstract 1
- 244000144725 Amygdalus communis Species 0.000 abstract 1
- 235000011437 Amygdalus communis Nutrition 0.000 abstract 1
- 241000218671 Ephedra Species 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 241000951473 Schizonepeta Species 0.000 abstract 1
- 240000004534 Scutellaria baicalensis Species 0.000 abstract 1
- 235000017089 Scutellaria baicalensis Nutrition 0.000 abstract 1
- 235000020224 almond Nutrition 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 201000010099 disease Diseases 0.000 description 6
- 241000721047 Danaus plexippus Species 0.000 description 4
- 239000000706 filtrate Substances 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 230000008506 pathogenesis Effects 0.000 description 3
- 208000000059 Dyspnea Diseases 0.000 description 2
- 206010013975 Dyspnoeas Diseases 0.000 description 2
- 208000029523 Interstitial Lung disease Diseases 0.000 description 2
- 208000032923 Lobar pneumonia Diseases 0.000 description 2
- 235000018992 Prunus glandulosa Nutrition 0.000 description 2
- 240000001619 Prunus glandulosa Species 0.000 description 2
- 235000013999 Prunus japonica Nutrition 0.000 description 2
- 208000037656 Respiratory Sounds Diseases 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000004868 gas analysis Methods 0.000 description 2
- 206010037833 rales Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 239000003643 water by type Substances 0.000 description 2
- 201000004813 Bronchopneumonia Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 241000288140 Gruiformes Species 0.000 description 1
- 201000005505 Measles Diseases 0.000 description 1
- 208000032023 Signs and Symptoms Diseases 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000007321 biological mechanism Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000000845 cartilage Anatomy 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 210000002216 heart Anatomy 0.000 description 1
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- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
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- 230000002685 pulmonary effect Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a medicine composition for treating infantile pneumonia. The medicine composition for treating infantile pneumonia contains the medicinal materials of ephedra, almond, liquorice, fistular onion stalk, schizonepeta, semen raphani, scutellaria baicalensis and the like. The medicine composition for treating infantile pneumonia disclosed by the invention has the advantages of being good in curative effect, fast to become effective, and free from toxic and side effects through clinical application and observation; moreover, the used raw material medicines are low in price and easy to get.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of pharmaceutical composition for the treatment of infantile pneumonia.
Background technology
Infantile pneumonia is mainly the pulmonary inflammation disease being caused by different pathogens, and the cause of disease is complicated, and infant is main manifestations mainly with heating, cough, dyspnea etc.Children's is due to its special dissect physiology structure, and trachea is relatively narrow, and cartilage is soft, and supporting role is less, and mucosa blood vessel is more, and mucous secretion is less, and air flue is comparatively dry, and poor to the removing ability of foreign body, respiratory tract easily blocks.Be multiple disease clinically at present, therefore need constantly to find new effective medicine.
Summary of the invention
The object of this invention is to provide a kind of pharmaceutical composition for the treatment of infantile pneumonia.
In order to realize object of the present invention, the invention provides a kind of pharmaceutical composition for the treatment of infantile pneumonia, the crude drug that it comprises following weight portion: Herba Ephedrae 1-5 part, Semen Armeniacae Amarum 5-15 part, Radix Glycyrrhizae 1-10 part, Bulbus Allii Fistulosi 1-10 part, Herba Schizonepetae 1-20 part, Semen Raphani 1-15 part, Radix Scutellariae 5-25 part and Caulis Bambusae In Taenia 1-10 part.
Preferably, the crude drug that the pharmaceutical composition for the treatment of infantile pneumonia of the present invention comprises following weight portion: 6 parts of 2 parts, Herba Ephedrae, 6 parts, Semen Armeniacae Amarum, 3 parts, Radix Glycyrrhizae, 8 parts of Bulbus Allii Fistulosi, 5 parts of Herba Schizonepetae, 7 parts of Semen Raphanis, 7 parts of Radix Scutellariaes and Caulis Bambusae In Taenia.
More preferably, the pharmaceutical composition for the treatment of infantile pneumonia of the present invention also comprises the crude drug of following weight portion: Herba Turczaninowiae Fastigiatae 5-25 part, Herba Boeae Hygrometricae 5-30 part, Pericarpium Arecae 1-10 part, Rhizoma begoniae pedatifidae 5-15 part, Rhizoma Dioscoreae 10-30 part, Radix Loxostigmatis griffithii 10-20 part, Radix Achyranthis Bidentatae 1-10 part, Herba Lanceae Tibeticae 1-10 part, Herba Vernoniae Cinereae 10-20 part, Fructus Crataegi 1-20 part, Liparis japonica (Miq.) Maxim. 5-25 part, Rhizoma Chuanxiong 1-10 part and Flos jasmini 1-10 part.
Most preferably, the pharmaceutical composition for the treatment of infantile pneumonia of the present invention also comprises the crude drug of following weight portion: 8 parts of 10 parts of Herba Turczaninowiae Fastigiatae, 10 parts of Herba Boeae Hygrometricaes, 6 parts of Pericarpium Arecae, 9 parts of Rhizoma begoniae pedatifidaes, 20 parts of Rhizoma Dioscoreaes, 15 parts of Radix Loxostigmatis griffithii, 6 parts of Radix Achyranthis Bidentataes, 5 parts of Herba Lanceae Tibeticae, 15 parts of Herba Vernoniae Cinereaes, 10 parts of Fructus Crataegis, 6 parts of Liparis japonica (Miq.) Maxim., 5 parts of Rhizoma Chuanxiongs and Flos jasmini.
Preferably, described pharmaceutical composition can be tablet, dispersible tablet, disintegrating tablet, instant, enteric coatel tablets, ointment or decoction.
Generally acknowledged that at present " organic conception ", " determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs ", " compound recipe use ", " compound compatibility medication is as used military forces " are the most scientific the most several large advantages of the traditional Chinese medical science, wherein " compound compatibility medication is as used military forces " is the original theory of Chinese medicine of very science.Each medicine tight compatibility all linked with one another as arrayed troops for battle in traditional Chinese medical science prescription is its effective means that is better than Western medicine formula.Tcm prescription theory is thought, each prescription, not only need to select the appropriate compatibility of suitable medicament according to etiology and pathogenesis, also should meet the basic structure of prescription simultaneously, the i.e. prescription compatibility theory of " monarch, minister, help, make ", the prescription compatibility of so-called " monarch, minister, help, make " is exactly that it is based upon the scientific matching on the comprehensive judgement basis of disease pathogenesis.In medical square tube cross too many levels, many target spots and integrate the biological mechanism regulating, can obtain than Western medicine more lastingly, therapeutic effect that more green natural has no side effect, and this curative effect is to be based upon on the accurate instruction of the original theory of above-mentioned traditional Chinese medical science tradition, the present invention is just following this principle.
For compositions of the present invention, according to the prescription compatibility theory of " monarch, minister, help, make ", Herba Vernoniae Cinereae and Rhizoma begoniae pedatifidae are monarch drug; Herba Ephedrae, Radix Glycyrrhizae, Semen Raphani, Herba Boeae Hygrometricae, Radix Achyranthis Bidentatae, Herba Lanceae Tibeticae are ministerial drug; Semen Armeniacae Amarum, Bulbus Allii Fistulosi, Herba Schizonepetae, Radix Scutellariae, Caulis Bambusae In Taenia, Rhizoma Dioscoreae, Liparis japonica (Miq.) Maxim., Pericarpium Arecae, Fructus Crataegi, Herba Turczaninowiae Fastigiatae and Rhizoma Chuanxiong are adjuvant drug; Radix Loxostigmatis griffithii and Flos jasmini are for making medicine.Effective combination of said medicine, supports mutually, and has obtained the useful technique effect that is satisfied with through clinical trial.
The specific embodiment
Below by embodiment, further illustrate the present invention.It should be understood that embodiments of the invention are for the present invention rather than limitation of the present invention are described.The simple modifications that essence according to the present invention is carried out the present invention all belongs to the scope of protection of present invention.Except as otherwise noted, the percent otherwise in the present invention is percetage by weight.
Embodiment decoction of the present invention
Take 2 grams, Herba Ephedrae, 6 grams, Semen Armeniacae Amarum, 3 grams, Radix Glycyrrhizae, 8 grams of Bulbus Allii Fistulosi, 5 grams of Herba Schizonepetae, 7 grams of Semen Raphanis, 7 grams of Radix Scutellariaes, 6 grams of Caulis Bambusae In Taenia, 10 grams of Herba Turczaninowiae Fastigiatae, 10 grams of Herba Boeae Hygrometricaes, 6 grams of Pericarpium Arecae, 9 grams of Rhizoma begoniae pedatifidaes, 20 grams of Rhizoma Dioscoreaes, 15 grams of Radix Loxostigmatis griffithii, 6 grams of Radix Achyranthis Bidentataes, 5 grams of Herba Lanceae Tibeticae, 15 grams of Herba Vernoniae Cinereaes, 10 grams of Fructus Crataegis, 6 grams of Liparis japonica (Miq.) Maxim., 8 grams of 5 grams of Rhizoma Chuanxiongs and Flos jasmini, pulverize, add 5000 ml waters, in the flask of condensing tube is housed, reflux is 6 hours, then filter, obtain filtrate 1 and filtering residue 1, in filtering residue 1, add 6000 ml waters, in being housed, heats by the flask of condensing tube 5 hours, filter, obtain filtrate 2 and filtering residue 2, merge described filtrate 1 and described filtrate 2, be concentrated into 3000 milliliters, be cooled to room temperature, obtain.
Experimental example
Physical data
Be collected in February, 2013 to 2014 year medical infant 49 examples of Dao Wo institute in May, male 25 examples wherein, female's 24 examples; 2 years old to 6 years old age, average (3.5 ± 1.2) year; Course of disease 1-11d, average (4.1 ± 1.7) d; Bronchopneumonia 34 examples, lobar pneumonia 9 examples, interstitial pneumonia 6 examples.
Diagnostic criteria meets the diagnostic criteria (Hu Yamei of the 7th edition mesobronchus pneumonia of all good fortune Chinese bush cherries of < < practical paidonosology > >, lobar pneumonia, interstitial pneumonia, Jiang Zaifang, all good fortune Chinese bush cherry practical paidonosologies [M]. Beijing: People's Health Publisher .2005:127-132.).
Inclusive criteria (1) meets the diagnostic criteria of infantile pneumonia; (2) 2 years old to the 6 years old age; (3) parents of hospitalized children informed consent.
Exclusion standard (1) merges measles, typhoid fever person; (2) merge the organic disease persons such as heart, Liver and kidney.
With the decoction of preparing in embodiment, treat, every day twice, each oral 150 milliliters, treat continuously 7 days.
Criterion of therapeutical effect (according to following document, formulate: State Administration of Traditional Chinese Medicine. traditional Chinese medical science disease Standardization of diagnosis and curative effect [M]. Nanjing: Nanjing Human is learned publishing house, 1994.)
Effective: 5d internal respiration difficulty and anoxic conditions disappear, pulmonary's rale disappears, and blood gas analysis is normal, and after 1 week, x-ray rabat shows that focus absorbs; Effective: remission in 5d, dyspnea and anoxic conditions are improved, and two lung rales reduce, and blood gas analysis recovers normally substantially, and after 1 week, x-ray rabat shows that focus takes a turn for the better; Invalid: above-mentioned symptom and sign are without improvement, and after 1 week, x-ray rabat shows that focus takes a turn for the better without absorbing.
Result
Through treatment, find in 49 routine patients effective 35 examples, effective 13 examples, invalid 1 example.
Claims (5)
1. a pharmaceutical composition for the treatment of infantile pneumonia, it is characterized in that the crude drug that it comprises following weight portion: Herba Ephedrae 1-5 part, Semen Armeniacae Amarum 5-15 part, Radix Glycyrrhizae 1-10 part, Bulbus Allii Fistulosi 1-10 part, Herba Schizonepetae 1-20 part, Semen Raphani 1-15 part, Radix Scutellariae 5-25 part and Caulis Bambusae In Taenia 1-10 part.
2. the pharmaceutical composition for the treatment of infantile pneumonia according to claim 1, is characterized in that, the crude drug that it comprises following weight portion: 6 parts of 2 parts, Herba Ephedrae, 6 parts, Semen Armeniacae Amarum, 3 parts, Radix Glycyrrhizae, 8 parts of Bulbus Allii Fistulosi, 5 parts of Herba Schizonepetae, 7 parts of Semen Raphanis, 7 parts of Radix Scutellariaes and Caulis Bambusae In Taenia.
3. the pharmaceutical composition for the treatment of infantile pneumonia according to claim 1 and 2, it is characterized in that, it also comprises the crude drug of following weight portion: Herba Turczaninowiae Fastigiatae 5-25 part, Herba Boeae Hygrometricae 5-30 part, Pericarpium Arecae 1-10 part, Rhizoma begoniae pedatifidae 5-15 part, Rhizoma Dioscoreae 10-30 part, Radix Loxostigmatis griffithii 10-20 part, Radix Achyranthis Bidentatae 1-10 part, Herba Lanceae Tibeticae 1-10 part, Herba Vernoniae Cinereae 10-20 part, Fructus Crataegi 1-20 part, Liparis japonica (Miq.) Maxim. 5-25 part, Rhizoma Chuanxiong 1-10 part and Flos jasmini 1-10 part.
4. the pharmaceutical composition for the treatment of infantile pneumonia according to claim 3, it is characterized in that, it also comprises the crude drug of following weight portion: 8 parts of 10 parts of Herba Turczaninowiae Fastigiatae, 10 parts of Herba Boeae Hygrometricaes, 6 parts of Pericarpium Arecae, 9 parts of Rhizoma begoniae pedatifidaes, 20 parts of Rhizoma Dioscoreaes, 15 parts of Radix Loxostigmatis griffithii, 6 parts of Radix Achyranthis Bidentataes, 5 parts of Herba Lanceae Tibeticae, 15 parts of Herba Vernoniae Cinereaes, 10 parts of Fructus Crataegis, 6 parts of Liparis japonica (Miq.) Maxim., 5 parts of Rhizoma Chuanxiongs and Flos jasmini.
5. according to the pharmaceutical composition of the treatment infantile pneumonia described in any one in claim 1-4, it is characterized in that, described pharmaceutical composition can be tablet, dispersible tablet, disintegrating tablet, instant, enteric coatel tablets, ointment or decoction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410379992.3A CN104096053A (en) | 2014-08-04 | 2014-08-04 | Medicine composition for treating infantile pneumonia |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410379992.3A CN104096053A (en) | 2014-08-04 | 2014-08-04 | Medicine composition for treating infantile pneumonia |
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| Publication Number | Publication Date |
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| CN104096053A true CN104096053A (en) | 2014-10-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410379992.3A Pending CN104096053A (en) | 2014-08-04 | 2014-08-04 | Medicine composition for treating infantile pneumonia |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105250647A (en) * | 2015-11-23 | 2016-01-20 | 刘建伟 | Medicine used for treating infantile pneumonia caused by obstruction of lung-qi |
| CN106310467A (en) * | 2016-08-27 | 2017-01-11 | 徐爱香 | Traditional Chinese medicine nursing atomizer for treating infantile pneumonia |
-
2014
- 2014-08-04 CN CN201410379992.3A patent/CN104096053A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105250647A (en) * | 2015-11-23 | 2016-01-20 | 刘建伟 | Medicine used for treating infantile pneumonia caused by obstruction of lung-qi |
| CN106310467A (en) * | 2016-08-27 | 2017-01-11 | 徐爱香 | Traditional Chinese medicine nursing atomizer for treating infantile pneumonia |
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Application publication date: 20141015 |
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