CN104971298A

CN104971298A - Pyrrosia leaf traditional Chinese medicine composition for treating phlegm-heat lung obstructing type asthma

Info

Publication number: CN104971298A
Application number: CN201410128129.0A
Authority: CN
Inventors: 刘黎明
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-04-02
Filing date: 2014-04-02
Publication date: 2015-10-14

Abstract

The invention relates to a pyrrosia leaf traditional Chinese medicine composition for treating phlegm-heat lung obstructing type asthma. The pyrrosia leaf traditional Chinese medicine composition is a medicament prepared from the following raw medicinal materials in parts by weight: 8-20 parts of blackberrylily rhizome, 8-20 parts of tatarian aster root, 8-20 parts of pinellia tuber, 8-20 parts of Chinese thorowax root, 8-20 parts of danshen root, 5g of Chinese ephedra, 6-15 parts of common coltsfoot flower, 6-15 parts of root of whiteflower hogfennel, 6-15parts of bitter orange, 6-15 parts of turmeric root-tuber, 9 parts of platycodon root, 9 parts of licorice root, 10-18 parts of earthworm, 10-18 parts of white mulberry root-bark, 10-18 parts of baical skullcap root and 20-60 parts of all grass of pyrrosia leaf. The traditional Chinese medicine composition provided by the invention is reasonable in formula and simple in process, gives full play to the characteristics of a good curative effect of the traditional Chinese medicines and no side effects, and is a satisfactory asthma medicament which is low in price, good in quality, small in dosage, quick in response, high in curative effect and convenient in use.

Description

A kind of Folium Pyrrosiae Chinese medicine composition for the treatment of accumulation of phlegm and heat in type asthma

Technical field

The present invention relates to tcm field, specifically, relate to a kind of Folium Pyrrosiae Chinese medicine composition for the treatment of accumulation of phlegm and heat in type asthma.

Background technology

Bronchial asthma (being called for short: asthma) is a kind of commonly encountered diseases, frequently-occurring disease, is affect one of able-bodied important diseases of people; Curing asthma is also one of universally acknowledged difficult medical problem, and its sickness rate rises year by year, can only alleviate at present, can not effect a radical cure this sick treatment; Main asthmatic medicament, also based on Western medicine, too relies on hormone, and toxic and side effects is very large, has certain infringement to the internal organs such as liver,kidney,spleen, lung of human body; Having a strong impact on people's physical and mental health simultaneously, also bring heavy financial burden and stress; Actively prevent and treat asthma, very urgent.

Accumulation of phlegm and heat in type asthma clinical main manifestations is: it is irritated that To Be Protected from Heat, and face lip is redder, sound pitch raucous breath during asthma attack, gurgling with sputum, laryngalgia, thick sputum and yellow, thirst and liking cold drink, oliguria with reddish urine, constipation with dry stool, red tongue with yellowish and greasy fur, slippery and rapid pulse.If companion sees that heating spontaneous perspiration person is for having wind heat exterior syndrome concurrently.Modern medicine is commonly referred to be the bronchial asthma in acute attack merging respiratory tract infection.The traditional Chinese medical science thinks asthma of heat type, the treatment of conventional " a thousand pieces of gold " DINGCHUAN TANG plus-minus, the current existing defects of Chinese medical discrimination, and asthma of heat type is not belong to asthma witnesses more, but its side's correspondence and effect poor, can not promote the use.

Summary of the invention

Technical problem to be solved by this invention is to provide a kind of Folium Pyrrosiae Chinese medicine composition for the treatment of accumulation of phlegm and heat in type asthma.

In order to overcome above-mentioned deficiency, realize object of the present invention, the invention provides a kind of Folium Pyrrosiae Chinese medicine composition for the treatment of asthma, it is characterized in that, it is the medicament be made up by weight of following bulk drugs:

Rhizoma Belamcandae, Radix Asteris, the Rhizoma Pinelliae, Radix Bupleuri, each 8 ~ 20 parts of Radix Salviae Miltiorrhizae, Herba Ephedrae (processed) 5 grams, Flos Farfarae, Radix Peucedani, Fructus Aurantii, each 6 ~ 15 parts of Radix Curcumae, each 9 parts of Radix Platycodonis, Radix Glycyrrhizae, Pheretima, Cortex Mori, each 10 ~ 18 parts of Radix Scutellariae, Folium Pyrrosiae herb 20 ~ 60 parts.

Preferably, the medicament be made up by weight of following bulk drugs of Chinese medicine composition of the present invention:

Rhizoma Belamcandae, Radix Asteris, the Rhizoma Pinelliae, Radix Bupleuri, each 15 parts of Radix Salviae Miltiorrhizae, Herba Ephedrae (processed) 5 parts, Flos Farfarae, Radix Peucedani, Fructus Aurantii, each 10 parts of Radix Curcumae, each 9 parts of Radix Platycodonis, Radix Glycyrrhizae, Pheretima, Cortex Mori, each 15 parts of Radix Scutellariae, Folium Pyrrosiae herb 50 parts.

The Traditional Chinese drug mixture for the treatment of asthma of the present invention, formula forms medical material used and pharmaceutic adjuvant all has national statutory standards, and dosage form is, and " Chinese Pharmacopoeia " records dosage form.Above-mentioned medicine comprises the medicine Chinese medicine compound for the treatment of asthma being combined the various dosage forms made with pharmaceutically acceptable carrier, such as tablet, capsule, soft capsule, pill, granule, drop pill or decoction etc.Preparation technique means well known in the art can be adopted to complete the preparation of pharmaceutical composition of the present invention: the preparation method of various dosage form can technique routinely, adds or do not add the adjuvants such as sucrose, sterilizing, make liquid preparation in decoction; Or add the adjuvants such as dextrin, granule processed or make other solid preparation, as tablet, capsule or micropill.

Traditional Chinese compound medicine of the present invention, through clinical verification for many years, has dispersing and descending lung-QI, preventing phlegm from forming and stopping coughing; Invigorating spleen to remove dampness, eliminating phlegm and relieving asthma; The effect of eliminating phlegm, the relieving convulsion Dingchuan of dispeling the wind.Sound pitch raucous breath when curing mainly asthma attack, gurgling with sputum, laryngalgia, thick sputum and yellow, thirst and liking cold drink, oliguria with reddish urine, constipation with dry stool, red tongue with yellowish and greasy fur, slippery and rapid pulse.

beneficial effect

Compared with existing Traditional Chinese medicinal prescription, a kind of Folium Pyrrosiae Chinese medicine composition for the treatment of accumulation of phlegm-heat in the lung asthma of the present invention, reasonable recipe, technique is simple, give full play to the speciality that Chinese Herbs is good, have no side effect, that one is good and cheap, consumption is little, instant effect, curative effect are high, gratifying asthma medication easy to use.

Detailed description of the invention

According to following embodiment, the present invention may be better understood.But those skilled in the art will readily understand, the content described by embodiment only for illustration of the present invention, and should can not limit the present invention described in detail in claims yet.

The preparation of embodiment 1 decoction of the present invention

Rhizoma Belamcandae, Radix Asteris, the Rhizoma Pinelliae, Radix Bupleuri, each 10 grams of Radix Salviae Miltiorrhizae, Herba Ephedrae (processed) 5 grams, Flos Farfarae, Radix Peucedani, Fructus Aurantii, each 6 grams of Radix Curcumae, each 9 grams of Radix Platycodonis, Radix Glycyrrhizae, Pheretima, Cortex Mori, each 10 grams of Radix Scutellariae, Folium Pyrrosiae herb 30 grams, adds the water of 10 times of medical material weight, heat 2 hours at 80 DEG C, filter, filtrate is concentrated into 150 milliliters, obtains final product, during use, every day sooner or later respectively once.

The preparation of embodiment 2 decoction of the present invention

Rhizoma Belamcandae, Radix Asteris, the Rhizoma Pinelliae, Radix Bupleuri, each 15 grams of Radix Salviae Miltiorrhizae, Herba Ephedrae (processed) 5 grams, Flos Farfarae, Radix Peucedani, Fructus Aurantii, each 10 grams of Radix Curcumae, each 9 grams of Radix Platycodonis, Radix Glycyrrhizae, Pheretima, Cortex Mori, each 15 grams of Radix Scutellariae, Folium Pyrrosiae herb 50 grams, adds the water of 10 times of medical material weight, heat 2 hours at 80 DEG C, filter, filtrate is concentrated into 150 milliliters, obtains final product, during use, every day sooner or later respectively once.

The preparation of embodiment 3 decoction of the present invention

Rhizoma Belamcandae, Radix Asteris, the Rhizoma Pinelliae, Radix Bupleuri, each 18 grams of Radix Salviae Miltiorrhizae, Herba Ephedrae (processed) 5 grams, Flos Farfarae, Radix Peucedani, Fructus Aurantii, each 15 grams of Radix Curcumae, each 9 grams of Radix Platycodonis, Radix Glycyrrhizae, Pheretima, Cortex Mori, each 15 grams of Radix Scutellariae, Folium Pyrrosiae herb 50 grams, adds the water of 10 times of medical material weight, heat 2 hours at 80 DEG C, filter, filtrate is concentrated into 150 milliliters, obtains final product, during use, every day sooner or later respectively once.

Embodiment is eliminated the phlegm experiment:

Select Kunming mouse 30, body weight 18 ~ 20g divides 3 groups at random.Often organize 10, gavage gives the solution of embodiment 2 respectively, high dose 20ml/kg. low dose group matched group 10ml/kg; The capacity water such as matched group, once a day, continuous three days, after last administration 30 minutes, the phenol red 0.5ml of every Mus lumbar injection 0.5%, after half an hour.De-cervical vertebra puts to death mice, faces upward position and is fixed on operation plate, and cut off neck center skin, be separated trachea, under larynx, injection needle is inserted trachea, ligation is fixed, and draws 5% carbonate ammonia natrium solution 0.5m1. rinse respiratory tract three times with syringe.Amount to flushing three times, totally nine times.Each flushing liquor is put into test tube, by 751 ultraviolet spectrophotometer colorimetrics.Experimental result is in table 1.

Table 1: the phlegm-dispelling functions of asthma capsule

With matched group than * P < 0.05 * * P < 0.01

T inspection between group, high low dose group is eliminated the phlegm all significant (P < 0.01 and P < 0.05)

Experiment conclusion: tested by relieving cough and expelling phlegm, proved invention has obvious cough-suppressing phlegm-dispelling functions.

Clinical verification:

Through hospital clinical checking, with domestic aminophylline for contrast, Ureteral Calculus is carried out to 120 routine patients.

Its criterion:

Three days clinical symptoms partial rcsponses of taking medicine are effective, and the three days clinical symptoms of taking medicine substantially disappearance person are recovery from illness.Its Cure is in table 2.

Table 2. clinical test results is as follows;

Group embodiment 1 embodiment 2 embodiment 3

Number 60 60 60

Clinic control number 10 13 11

Clinic control rate (%) 16.67 21.67 18.33

Effective number 24 26 21

Obvious effective rate (%) 40.00 43.33 35.00

Improvement number 17 16 20

Improvement rate (%) 28.33 26.67 33.33

Invalid number 958

Inefficiency (%) 15.00 8.33 13.33

Total efficiently individual quantity 51 55 52

Total effective rate (%) 85.00 91.67 86.67.

The present invention is by long-term research and practice, and reasonable recipe, technique is simple, gives full play to the speciality that Chinese Herbs is good, have no side effect, and is that one is good and cheap, consumption is little, instant effect, curative effect are high, gratifying asthma medication easy to use.

Model case:

King so-and-so, female, 53 years old, when 10 years old flu cause bronchitis, in the past all with western medicine and medical practitioners treatment, outpatient service, be in hospital transfusion for many years, because of malpractice, drag into chronic bronchitis and chronic bronchial asthma, in decades recurrent exerbation.Cough vapour lock, abundant expectoration during morbidity, with heating, asthma, rapid breathing, face purple is unable, has a strong impact on work and life.Average onset 5-6 time within 1 year, how in autumn and winter outbreak, more than 40 years of front and back.In May, 1998, inventor is said " your Therapeutic Method is very special, cures the disease time anosis, treating winter disease in summer, and asthma is disappearing unconsciously ".That day in the Beginning of summer, when without symptoms of asthma, start to take medicine of the present invention, take drug withdrawal after 5 courses for the treatment of.Autumn and winter all do not fall ill then.After this in past 5 years, patient has no and sends out asthma again.

Claims

1. treat the Folium Pyrrosiae Chinese medicine composition of accumulation of phlegm and heat in type asthma for one kind, it is characterized in that, it is the medicament be made up by weight of following bulk drugs: Rhizoma Belamcandae, Radix Asteris, the Rhizoma Pinelliae, Radix Bupleuri, each 8 ~ 20 parts of Radix Salviae Miltiorrhizae, Herba Ephedrae (processed) 5 grams, Flos Farfarae, Radix Peucedani, Fructus Aurantii, each 6 ~ 15 parts of Radix Curcumae, each 9 parts of Radix Platycodonis, Radix Glycyrrhizae, Pheretima, Cortex Mori, each 10 ~ 18 parts of Radix Scutellariae, Folium Pyrrosiae herb 20 ~ 60 parts.

2. according to a kind of Folium Pyrrosiae Chinese medicine composition for the treatment of accumulation of phlegm and heat in type asthma described in claim 1, it is characterized in that, it is the medicament be made up by weight of following bulk drugs: Rhizoma Belamcandae, Radix Asteris, the Rhizoma Pinelliae, Radix Bupleuri, each 15 parts of Radix Salviae Miltiorrhizae, Herba Ephedrae (processed) 5 parts, Flos Farfarae, Radix Peucedani, Fructus Aurantii, each 10 parts of Radix Curcumae, each 9 parts of Radix Platycodonis, Radix Glycyrrhizae, Pheretima, Cortex Mori, each 15 parts of Radix Scutellariae, Folium Pyrrosiae herb 50 parts.