CN113654289A - Reagent refrigeration device and refrigeration method - Google Patents
Reagent refrigeration device and refrigeration method Download PDFInfo
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- CN113654289A CN113654289A CN202111000758.1A CN202111000758A CN113654289A CN 113654289 A CN113654289 A CN 113654289A CN 202111000758 A CN202111000758 A CN 202111000758A CN 113654289 A CN113654289 A CN 113654289A
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- 239000003153 chemical reaction reagent Substances 0.000 title claims abstract description 136
- 238000005057 refrigeration Methods 0.000 title claims abstract description 106
- 238000000034 method Methods 0.000 title claims abstract description 49
- 239000003507 refrigerant Substances 0.000 claims abstract description 144
- 239000011229 interlayer Substances 0.000 claims abstract description 12
- 239000007788 liquid Substances 0.000 claims description 108
- 239000002826 coolant Substances 0.000 claims description 27
- 239000004065 semiconductor Substances 0.000 claims description 25
- 238000001816 cooling Methods 0.000 claims description 7
- 238000011217 control strategy Methods 0.000 claims description 5
- 229920000742 Cotton Polymers 0.000 claims description 4
- 230000003213 activating effect Effects 0.000 claims 2
- 239000012212 insulator Substances 0.000 claims 2
- 230000008569 process Effects 0.000 abstract description 14
- 230000000694 effects Effects 0.000 abstract description 13
- 238000004321 preservation Methods 0.000 description 10
- 108010066057 cabin-1 Proteins 0.000 description 6
- 230000008859 change Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 230000017525 heat dissipation Effects 0.000 description 3
- 239000006260 foam Substances 0.000 description 2
- 238000009413 insulation Methods 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
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Classifications
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D11/00—Self-contained movable devices, e.g. domestic refrigerators
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D23/00—General constructional features
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D23/00—General constructional features
- F25D23/003—General constructional features for cooling refrigerating machinery
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D23/00—General constructional features
- F25D23/006—General constructional features for mounting refrigerating machinery components
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D29/00—Arrangement or mounting of control or safety devices
- F25D29/005—Mounting of control devices
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D29/00—Arrangement or mounting of control or safety devices
- F25D29/008—Alarm devices
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2201/00—Insulation
- F25D2201/10—Insulation with respect to heat
- F25D2201/12—Insulation with respect to heat using an insulating packing material
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2600/00—Control issues
- F25D2600/06—Controlling according to a predetermined profile
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2700/00—Means for sensing or measuring; Sensors therefor
- F25D2700/12—Sensors measuring the inside temperature
Abstract
The invention discloses a reagent refrigerating device and a refrigerating method, and belongs to the technical field of refrigeration. The reagent bin is connected with the secondary refrigerant box through a pipeline to form a circulation loop, the reagent bin is provided with an interlayer and a flow passage, and the secondary refrigerant box is used for providing and storing secondary refrigerant; the refrigerating device is used for refrigerating the secondary refrigerant flowing through the interlayer and the flow channel, so that the reagent bin is refrigerated, the secondary refrigerant box stores a large amount of secondary refrigerant, the secondary refrigerant amount in the whole refrigerating process is increased, and the refrigerating effect is improved.
Description
Technical Field
The invention relates to the technical field of refrigeration, in particular to a reagent refrigeration device and a refrigeration method.
Background
For most sample analyzers, reagents on reagent disks of the sample analyzers need to be stored at low temperature, and the temperature of a reagent cabin is controlled below 10 ℃, so that the service life of the reagents is prolonged. Therefore, the reagents need to be refrigerated.
At present, the existing instruments are refrigerated by adopting a semiconductor device, mostly, the cold end of a refrigerating sheet is directly contacted with the bottom of a reagent tray, and the heat at the hot end of the refrigerating sheet is transferred to the outside in a heat conduction or forced convection mode; the heat at the hot end of the refrigerating sheet cannot be discharged in time, so that the refrigerating efficiency of the refrigerating sheet is reduced, and the refrigerating effect of the refrigerating sheet is influenced, so that the refrigerating effect of the reagent is reduced; the heat transfer by the semiconductor can cause the temperature at the bottom of the reagent tray to be uneven, which is not beneficial to the storage of the reagent.
The above is only for the purpose of assisting understanding of the technical aspects of the present invention, and does not represent an admission that the above is prior art.
Disclosure of Invention
The invention mainly aims to provide a reagent refrigerating device and a refrigerating method, and aims to solve the technical problem that a reagent bin in the prior art is low in refrigerating effect.
In order to achieve the aim, the invention provides a reagent refrigerating device which comprises a reagent bin, a secondary refrigerant box, a driving device and a refrigerating device, wherein the reagent bin is connected with the secondary refrigerant box through a pipeline and forms a circulation loop;
the secondary refrigerant box is used for providing secondary refrigerant;
the driving device is arranged between the reagent bin and the secondary refrigerant box and is used for enabling the secondary refrigerant to flow through the refrigerating device and the reagent bin through the pipeline;
the refrigerating device is arranged between the driving device and the secondary refrigerant box and used for providing a cold source and refrigerating the secondary refrigerant flowing through.
Optionally, the reagent cabin is provided with an interlayer and a flow channel, and the flow channel is connected with the pipeline.
Optionally, the reagent chamber is provided with a heat preservation device.
Optionally, the insulation means comprises insulation wool.
Optionally, the reagent chamber and the refrigeration device are provided with temperature sensors, and the temperature sensors comprise a first temperature sensor and a second temperature sensor.
Optionally, the refrigeration device is a semiconductor refrigeration device.
Optionally, a plurality of heat dissipation devices are arranged on two sides of the refrigeration device.
Optionally, the heat sink comprises a fan.
Optionally, the coolant tank is provided with a level sensor.
In order to achieve the above object, the present invention further provides a refrigeration method, which is applied to the reagent refrigeration apparatus, where the reagent refrigeration apparatus includes a reagent compartment, a coolant tank, a driving device, and a refrigeration device, and the method includes:
acquiring the liquid level state of the secondary refrigerant in the secondary refrigerant box;
when the liquid level state meets a preset liquid level state, starting the driving device and the refrigerating device, and refrigerating the secondary refrigerant through the refrigerating device;
and conveying the refrigerated secondary refrigerant to the reagent bin through the driving device.
Optionally, the refrigeration device is provided with a first temperature sensor;
when the liquid level state satisfies the preset liquid level state, the driving device and the refrigerating device are started, and after the secondary refrigerant is refrigerated through the refrigerating device, the method further comprises the following steps:
acquiring the refrigerating temperature of the refrigerating device acquired by the first temperature sensor;
and controlling the temperature of the refrigerating device according to a preset control strategy.
Optionally, the reagent chamber is provided with a second temperature sensor;
when the liquid level state satisfies the preset liquid level state, the driving device and the refrigerating device are started, and after the refrigerating device refrigerates the secondary refrigerant, the refrigerating device further comprises:
acquiring the temperature of the reagent bin acquired by the second temperature sensor;
and when the temperature of the reagent bin is smaller than a preset temperature threshold value, closing the driving device and the refrigerating device, and giving an alarm.
Optionally, when the liquid level state satisfies a preset liquid level state, the driving device and the refrigeration device are started, and after the secondary refrigerant is refrigerated by the refrigeration device, the method further includes:
and when the preset liquid level state is a low liquid level state, alarming and reminding are carried out to prompt the addition of the secondary refrigerant.
Optionally, when the liquid level state satisfies a preset liquid level state, the driving device and the refrigeration device are started, and after the secondary refrigerant is refrigerated by the refrigeration device, the method further includes:
and when the current liquid level state is detected to be a liquid level empty state, closing the driving device and the refrigerating device, and giving an alarm.
In the invention, a reagent bin is connected with a secondary refrigerant box through a pipeline to form a circulation loop, the reagent bin is provided with an interlayer and a flow passage, and the secondary refrigerant box is used for providing and storing secondary refrigerant; refrigerating the secondary refrigerant flowing through the interlayer and the flow channel by a refrigerating device, so as to refrigerate the reagent bin, uniformly cool the reagent in the reagent bin and prolong the service life of the reagent bin; the refrigerating device is simple to maintain and not easy to damage, and maintainability is improved. The secondary refrigerant box stores a large amount of secondary refrigerant, so that the secondary refrigerant amount in the whole refrigeration process is increased, and the refrigeration effect is improved.
Drawings
FIG. 1 is a schematic view of the construction of one embodiment of a reagent cooler according to the present invention;
FIG. 2 is a schematic flow diagram of a first embodiment of the refrigeration process of the present invention;
FIG. 3 is a schematic flow diagram of a second embodiment of the refrigeration process of the present invention;
FIG. 4 is a schematic flow diagram of a third embodiment of a refrigeration process of the present invention;
FIG. 5 is a flow chart of the refrigeration method according to the third embodiment of the present invention;
fig. 6 is a schematic flow chart of a refrigeration method according to a fourth embodiment of the invention.
The reference numbers illustrate:
| reference numerals | Name (R) | Reference numerals | Name (R) |
| 1 | Reagent storehouse | 5 | Heat sink device |
| 2 | Secondary refrigerant box | 6 | First temperature sensor |
| 3 | Drive device | 7 | Second temperature sensor |
| 4 | Refrigerating |
8 | Liquid level sensor |
The implementation, functional features and advantages of the objects of the present invention will be further explained with reference to the accompanying drawings.
Detailed Description
It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Referring to fig. 1, fig. 1 is a schematic structural view of a reagent refrigerating apparatus according to an embodiment of the present invention. The invention provides a reagent refrigerating device.
In the embodiment, the reagent refrigeration device comprises a reagent bin 1, a secondary refrigerant box 2, a driving device 3 and a refrigeration device 4, wherein the reagent bin 1 is connected with the secondary refrigerant box 2 through a pipeline and forms a circulation loop; the secondary refrigerant box 2 is used for providing secondary refrigerant;
the driving device 3 is arranged between the reagent bin 1 and the secondary refrigerant box 2 and is used for enabling the secondary refrigerant to flow through the refrigerating device 4 and the reagent bin 1 through the pipelines;
the refrigerating device 4 is arranged between the driving device 3 and the secondary refrigerant box 2 and is used for providing a cold source and refrigerating the secondary refrigerant flowing through.
It should be noted that the reagent chamber 1 is a device for storing a reagent, the reagent chamber is provided with an interlayer and a flow channel, the flow channel is connected with a pipeline, a secondary refrigerant flows through the interlayer and the flow channel to refrigerate the reagent chamber, the reagent chamber is provided with a heat preservation device, the heat preservation device may be heat preservation cotton, heat preservation foam or other devices capable of preserving heat, and this embodiment is not limited thereto; the heat preservation cotton is wrapped up outside the reagent storehouse and is kept warm to the reagent storehouse and prevent the temperature loss. The secondary refrigerant box 2 is used for storing secondary refrigerant and can also be used for filling the secondary refrigerant of the circulating system; the driving device 3 is a power source for the coolant circulation, such as a pump, and may be another driving device for driving the coolant circulation, which is not limited in this embodiment; the refrigerating device 4 is a semiconductor refrigerating module, provides a cold source, and refrigerates the secondary refrigerant through the semiconductor refrigerating module.
It should be understood that the reagent chamber 1 and the refrigerating device 4 are both provided with temperature sensors, the temperature sensor of the refrigerating device 4 is a first temperature sensor 6, and the first temperature sensor is mounted on the refrigerating device and used for detecting the temperature during refrigeration, controlling the refrigerating device 4 and improving the temperature control precision of the refrigerating device 4; the temperature sensor of the reagent cabin 1 is a second temperature sensor 7, is arranged outside the reagent cabin 1 and is used for detecting the temperature of the reagent cabin 1 so as to avoid the reagent cabin 1 from being frozen under a fault state; on both sides of the cooling device 4, there are also provided several heat sinks 5, such as fans. More than 2 heat dissipation devices 5 are arranged on two sides of the refrigerating device 4 to dissipate heat of the refrigerating device 4, so that heat generated by the refrigerating device during working is timely dissipated, and the refrigerating effect is improved; a liquid level sensor 8 is arranged in the secondary refrigerant box 2, and the liquid level state of the secondary refrigerant in the secondary refrigerant box 2 is judged according to the signal of the liquid level sensor 8.
In the specific implementation, the outlet of the reagent cabin 1 returns to the inlet above the secondary refrigerant tank 2 through a pipeline, the outlet at the bottom of the secondary refrigerant tank 2 is connected to the driving device 3 through a pipeline, the outlet of the driving device 3 is connected to the inlet of the refrigerating device 4 through a pipeline, and the outlet of the refrigerating device 4 is connected to the inlet of the reagent cabin 1 through a pipeline.
In the embodiment, the reagent bin is connected with the secondary refrigerant box through a pipeline to form a circulating loop, the reagent bin is provided with an interlayer and a flow passage, and the secondary refrigerant box is used for providing and storing secondary refrigerant; refrigerating the secondary refrigerant flowing through the interlayer and the flow channel by a refrigerating device, so as to refrigerate the reagent bin, uniformly cool the reagent in the reagent bin and prolong the service life of the reagent bin; the refrigerating device is simple to maintain and not easy to damage, and maintainability is improved. The secondary refrigerant box stores a large amount of secondary refrigerant, so that the secondary refrigerant amount in the whole refrigeration process is increased, and the refrigeration effect is improved.
As shown in FIG. 1, those skilled in the art will appreciate that the configuration shown in FIG. 1 does not constitute a limitation of the reagent cooler, and may include more or fewer components than shown, or some components in combination, or a different arrangement of components.
Referring to fig. 2, fig. 2 is a schematic flow chart of a first embodiment of the refrigeration method of the present invention. In order to achieve the above object, the present invention further provides a first embodiment of a refrigeration method, which is used in the above reagent refrigeration apparatus, and the reagent refrigeration apparatus of this embodiment can be referred to fig. 1.
In a first embodiment, the refrigeration method comprises the steps of:
the reagent refrigerating device comprises a reagent bin, a secondary refrigerant box, a driving device and a refrigerating device;
step S10: and acquiring the liquid level state of the secondary refrigerant in the secondary refrigerant box.
The secondary refrigerant box is a device for storing the secondary refrigerant, the secondary refrigerant is stored in the secondary refrigerant box, the secondary refrigerant is convenient to add, the secondary refrigerant amount in the whole refrigeration process is increased, the refrigeration capacity is increased, and the refrigeration effect of the reagent bin is improved; the liquid level state of the secondary refrigerant comprises a liquid level empty state, a liquid level low state and a liquid level normal state.
In the specific implementation, the secondary refrigerant is stored in a secondary refrigerant box, a liquid level sensor is arranged in the secondary refrigerant box, and the embodiment takes a floater liquid level sensor as an example for description; and a floater is arranged on the floater liquid level sensor to judge the liquid level of the secondary refrigerant in the secondary refrigerant tank. And obtaining the corresponding liquid level state of the secondary refrigerant by acquiring the float signal acquired by the liquid level sensor.
Step S20: and when the liquid level state meets a preset liquid level state, starting the driving device and the refrigerating device, and refrigerating the secondary refrigerant through the refrigerating device.
It should be understood that the preset liquid level state refers to a liquid level low state and a liquid level normal state; the driving device refers to a pump for circulating the secondary refrigerant; the refrigerating device refers to a semiconductor refrigerating module.
It should be noted that, when the liquid level state of the secondary refrigerant is a normal liquid level state, which indicates that the secondary refrigerant can be refrigerated at this time, the refrigeration function is started, that is, the pump, the semiconductor refrigeration module and the fan are turned on, the secondary refrigerant is delivered through the pump, the semiconductor refrigeration module is used to refrigerate the secondary refrigerant, and the fan is turned on to radiate the semiconductor refrigeration module.
Step S30: and conveying the refrigerated secondary refrigerant to the reagent bin through the driving device.
It should be understood that after refrigerating the secondary refrigerant, the refrigerated secondary refrigerant is conveyed to the reagent bin through the pump, the reagent bin is provided with an interlayer and a flow channel, and the refrigerated secondary refrigerant transfers the cold feeling to the reagent bin after flowing through the interlayer and the flow channel to refrigerate the reagent bin; because the reagent storehouse intermediate layer is full of liquid, reagent storehouse contact secondary refrigerant, cold volume can fully transmit to the reagent storehouse, improves refrigeration effect, and the flow of secondary refrigerant can effectively guarantee that the reagent storehouse is even cold degree.
In specific implementation, the exterior of the reagent bin is further wrapped with a heat preservation device, such as heat preservation cotton or foam, which is not limited in this embodiment; the temperature of the reagent bin is kept warm by the heat preservation device, so that the temperature change of the reagent bin is slow.
In the embodiment, the liquid level state of the secondary refrigerant in the secondary refrigerant box is obtained; when the liquid level state meets a preset liquid level state, starting the driving device and the refrigerating device, and refrigerating the secondary refrigerant through the refrigerating device; and conveying the refrigerated secondary refrigerant to the reagent bin through the driving device. The secondary refrigerant is stored in the secondary refrigerant box and the liquid level state of the secondary refrigerant in the secondary refrigerant box is detected in real time, when the liquid level state of the secondary refrigerant is a normal liquid level state or a low liquid level state, the refrigerating function can be normally started to refrigerate the secondary refrigerant, the refrigerated secondary refrigerant is conveyed to the reagent bin through the pump, the reagent bin is in contact with the secondary refrigerant, the cold energy can be fully transmitted to the reagent bin, so that the reagent in the reagent bin is uniformly cooled, and the service life of the reagent bin is prolonged; the secondary refrigerant box stores a large amount of secondary refrigerant, so that the secondary refrigerant amount in the whole refrigeration process is increased, the refrigeration effect is improved, and the reagent bin is wrapped by the heat preservation device, so that the effect of rapid refrigeration can be achieved.
Referring to fig. 3, fig. 3 is a schematic flow chart of a second embodiment of a refrigeration method according to the present invention.
Based on the first embodiment, the refrigeration method of the present embodiment further includes, after the step S20:
the refrigerating device is provided with a first temperature sensor;
step S21: and acquiring the refrigerating temperature of the refrigerating device acquired by the first temperature sensor.
In this embodiment, the refrigeration device is a semiconductor refrigeration module, the first temperature sensor is installed on the refrigeration device, and the current refrigeration temperature T1 is obtained by detecting the temperature of the semiconductor refrigeration module in real time.
Step S22: and controlling the temperature of the refrigerating device according to a preset control strategy.
It should be understood that the preset control strategy refers to a PID control algorithm strategy, PID is an abbreviation of proportionality, Integral, Differential, and the essence of the PID control algorithm is to operate according to a function relationship of proportion, Integral, and Differential according to an input deviation value, and the operation result is used to control output. The duty ratio of the semiconductor refrigeration module and the fan is controlled through a PID control algorithm, and in the embodiment, the duty ratio refers to the percentage of the refrigeration time of the semiconductor refrigeration module and the heat dissipation time of the fan in the working time of the whole refrigeration device.
The temperature control of the refrigeration apparatus means that the temperature T1 of the semiconductor refrigeration module is maintained within a set range; for example, the set refrigeration temperature is 3-5 ℃, the temperature of the semiconductor refrigeration module is controlled through a PID control algorithm, so that the temperature of the semiconductor refrigeration module is maintained at 3-5 ℃, and the temperature is accurately controlled.
In the embodiment, the refrigeration temperature of the refrigeration device acquired by the first temperature sensor is acquired; controlling the temperature of the refrigerating device according to a preset control strategy; the temperature of the semiconductor refrigeration module is controlled by detecting the temperature of the semiconductor refrigeration module in real time and using a PID control algorithm, so that the temperature of the semiconductor refrigeration module is maintained within a set temperature range, and the temperature control precision during refrigeration is improved.
Referring to fig. 4, fig. 4 is a schematic flow chart of a third embodiment of a refrigeration method according to the present invention.
Based on the first embodiment, the refrigeration method of the present embodiment further includes, after the step S20:
the reagent bin is provided with a second temperature sensor;
step S21': and acquiring the temperature of the reagent bin acquired by the second temperature sensor.
It should be noted that the second temperature sensor is located outside the reagent chamber and is used for detecting the temperature of the reagent chamber. The state of the reagent bin can be known by acquiring the temperature T2 of the reagent bin acquired by the second temperature sensor in real time, and when the temperature T2 of the reagent bin changes, the state can be known and processed in time so as to prevent the stored reagent from being stored according to the preset temperature.
Step S22': and when the temperature of the reagent bin is smaller than a preset temperature threshold value, closing the driving device and the refrigerating device, and giving an alarm.
It should be understood that the preset temperature threshold refers to 0 ℃, as shown in fig. 5, fig. 5 is an overall flow chart of the refrigeration method, and when the temperature T2 of the reagent chamber is detected to be less than 0 ℃, it can be determined that the refrigeration is failed at this time, and the cold feeling of the refrigeration is too low, so that the reagent chamber is frozen, and thus the reagent is not effectively stored.
In specific implementation, when the temperature T2 of the reagent bin is detected to be less than 0 ℃, the refrigeration is failed at the moment, and the refrigeration needs to be stopped; the pump, the semiconductor refrigeration module, and the fan providing the coolant are turned off. And an alarm is given to remind a user that the refrigerating device has a fault.
In the embodiment, the temperature of the reagent bin acquired by the second temperature sensor is acquired; when the temperature of the reagent bin is smaller than a preset temperature threshold value, the driving device and the refrigerating device are closed, and an alarm is given; the temperature of the reagent bin can be quickly known by timely acquiring the temperature of the reagent bin collected by the temperature sensor positioned in the reagent bin, when the temperature of the reagent bin is less than 0 ℃, the refrigeration is determined to be failed, the refrigeration is stopped in time and an alarm is given, and the maintainability of the refrigeration device is improved.
Referring to fig. 6, fig. 6 is a schematic flow chart of a fourth embodiment of a refrigeration method according to the present invention.
Based on the first embodiment, after the step 20, the refrigeration method of this embodiment further includes:
step S21 ″: and when the preset liquid level state is a low liquid level state, alarming and reminding are carried out to prompt the addition of the secondary refrigerant.
It should be noted that the preset liquid level state is a liquid level low state and a liquid level normal state.
Further, the step of obtaining the liquid level state of the coolant in the coolant tank comprises the steps of: acquiring a float signal of the secondary refrigerant tank acquired by the liquid level sensor; determining the marking information of the secondary refrigerant tank according to the float signal; determining the liquid level state of the secondary refrigerant in the secondary refrigerant box according to the marking information;
in this embodiment, the liquid level sensor is a float liquid level sensor, a 2-step float is arranged on the float liquid level sensor, and a corresponding float signal is detected, for example, the volume of the coolant tank is 5L, and the first-step float signal obtained by the liquid level sensor corresponds to the marking information at 50ML of the coolant tank, so that the liquid level state of the coolant in the coolant tank at that time can be obtained according to the marking information of the coolant tank, and the liquid level state of the coolant corresponding to the marking information at 50ML of the coolant tank can be known to be a liquid level low state. For example, the volume of the coolant tank is 10L, and the corresponding marking information obtained according to the float signal is at 5L of the coolant tank, the liquid level state of the coolant can be determined to be a normal liquid level state according to the marking information of the coolant tank.
It should be understood that, when the liquid level state of the secondary refrigerant is the liquid level low state, it indicates that the secondary refrigerant amount at this time can perform normal refrigeration, but the liquid level state of the secondary refrigerant may change in the refrigeration process and become the liquid level empty state, which results in poor refrigeration effect, so that when the liquid level state is the liquid level low state, the pump, the semiconductor refrigeration module and the fan are started to perform refrigeration, and meanwhile, the alarm is given to remind a user to add the secondary refrigerant, so that the secondary refrigerant is added while the refrigeration effect is not affected.
In this embodiment, after the alarm is given, the liquid level state of the coolant in the coolant tank is detected in real time, and when the change of the liquid level state of the coolant is detected, for example, a user adds the coolant according to the alarm information, the liquid level state of the coolant needs to be updated in time. And if the liquid level state of the updated secondary refrigerant is detected to be a normal liquid level state, the alarm device can be closed.
In specific implementation, when the current liquid level state is detected to be a liquid level empty state, it is indicated that a user does not add the secondary refrigerant in the secondary refrigerant tank according to the alarm information, or the liquid level state of the secondary refrigerant changes to be the liquid level empty state in the refrigeration process of the refrigeration device, it is indicated that no secondary refrigerant can be used for refrigeration, in order to prevent the semiconductor refrigeration module from being ineffective in refrigeration, the pump, the semiconductor refrigeration module and the fan are turned off to stop refrigeration, and an alarm is given to remind the user to add the secondary refrigerant in the secondary refrigerant tank; and detecting whether the liquid level state of the secondary refrigerant is changed or not in real time. When the liquid level state of the secondary refrigerant is detected to be changed, for example, the liquid level state of the secondary refrigerant is changed from a liquid level empty state to a liquid level low state, the pump, the semiconductor refrigeration module and the fan can be started to refrigerate the secondary refrigerant in the current liquid level state, the liquid level state of the secondary refrigerant at the moment is also in the liquid level low state, the alarm can be continuously given out to prompt a user to continuously add the secondary refrigerant, and when the liquid level state of the current secondary refrigerant is detected to be changed into the liquid level normal state, the alarm device can be closed to continuously refrigerate the secondary refrigerant.
In the embodiment, when the preset liquid level state is a liquid level low state, alarm reminding is performed to prompt that secondary refrigerant is added; the liquid level state of the secondary refrigerant in the secondary refrigerant box is detected in real time through the liquid level sensor, when the liquid level is in a low state, an alarm is given, and the reduction of the refrigerating capacity caused by the reduction of the liquid level of the secondary refrigerant can be effectively prevented.
It should be understood that the above is only an example, and the technical solution of the present invention is not limited in any way, and in a specific application, a person skilled in the art may set the technical solution as needed, and the present invention is not limited thereto.
It should be noted that the above-described work flows are only exemplary, and do not limit the scope of the present invention, and in practical applications, a person skilled in the art may select some or all of them to achieve the purpose of the solution of the embodiment according to actual needs, and the present invention is not limited herein.
In addition, the technical details that are not described in detail in this embodiment may refer to the refrigeration method provided in any embodiment of the present invention, and are not described herein again.
Further, it is to be noted that, in this document, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or system that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or system. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other like elements in a process, method, article, or system that comprises the element.
The above-mentioned serial numbers of the embodiments of the present invention are merely for description and do not represent the merits of the embodiments.
Through the above description of the embodiments, those skilled in the art will clearly understand that the method of the above embodiments can be implemented by software plus a necessary general hardware platform, and certainly can also be implemented by hardware, but in many cases, the former is a better implementation manner. Based on such understanding, the technical solution of the present invention or portions thereof that contribute to the prior art may be embodied in the form of a software product, where the computer software product is stored in a storage medium (e.g. Read Only Memory (ROM)/RAM, magnetic disk, optical disk), and includes several instructions for enabling a terminal device (e.g. a mobile phone, a computer, a server, or a network device) to execute the method according to the embodiments of the present invention.
The above description is only a preferred embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes, which are made by using the contents of the present specification and the accompanying drawings, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.
Claims (14)
1. The reagent refrigeration device is characterized by comprising a reagent bin, a secondary refrigerant box, a driving device and a refrigeration device, wherein the reagent bin is connected with the secondary refrigerant box through a pipeline to form a circulation loop;
the secondary refrigerant box is used for providing secondary refrigerant;
the driving device is arranged between the reagent bin and the secondary refrigerant box and is used for enabling the secondary refrigerant to flow through the refrigerating device and the reagent bin through the pipeline;
the refrigerating device is arranged between the driving device and the secondary refrigerant box and used for providing a cold source and refrigerating the secondary refrigerant flowing through.
2. A reagent cooler as set forth in claim 1 wherein said reagent chamber is provided with an interlayer and a flow passage, said flow passage being connected to said conduit.
3. A reagent cooler as claimed in claim 1, wherein the reagent chamber is provided with a thermal insulator.
4. A reagent cooler as set forth in claim 3 wherein said thermal insulator comprises thermal cotton.
5. A reagent chilling apparatus according to any one of claims 1 to 4, wherein the reagent chamber and the chilling apparatus are provided with temperature sensors, the temperature sensors including a first temperature sensor and a second temperature sensor.
6. A reagent chilling apparatus according to any one of claims 1 to 4, wherein said chilling apparatus is a semiconductor chilling apparatus.
7. A reagent chilling apparatus according to any one of claims 1 to 4, wherein heat sinks are provided on either side of the chilling apparatus.
8. A reagent chilling apparatus according to claim 7, wherein the heat sink means includes a fan.
9. A reagent cold storage device according to any one of claims 1 to 4 wherein the coolant tank is provided with a level sensor.
10. A method of refrigeration, for use in a reagent refrigeration apparatus according to any one of claims 1 to 9, the reagent refrigeration apparatus comprising a reagent chamber, a coolant tank, a drive means and a refrigeration apparatus, the method comprising:
acquiring the liquid level state of the secondary refrigerant in the secondary refrigerant box;
when the liquid level state meets a preset liquid level state, starting the driving device and the refrigerating device, and refrigerating the secondary refrigerant through the refrigerating device;
and conveying the refrigerated secondary refrigerant to the reagent bin through the driving device.
11. A refrigerating method as recited in claim 10, wherein said refrigerating apparatus is provided with a first temperature sensor;
when the liquid level state satisfies the preset liquid level state, the driving device and the refrigerating device are started, and after the secondary refrigerant is refrigerated through the refrigerating device, the method further comprises the following steps:
acquiring the refrigerating temperature of the refrigerating device acquired by the first temperature sensor;
and controlling the temperature of the refrigerating device according to a preset control strategy.
12. The refrigeration method of claim 10 wherein said reagent compartment is provided with a second temperature sensor;
when the liquid level state satisfies the preset liquid level state, the driving device and the refrigerating device are started, and after the refrigerating device refrigerates the secondary refrigerant, the refrigerating device further comprises:
acquiring the temperature of the reagent bin acquired by the second temperature sensor;
and when the temperature of the reagent bin is smaller than a preset temperature threshold value, closing the driving device and the refrigerating device, and giving an alarm.
13. The method as claimed in claim 10, wherein the step of activating the driving device and the cooling device when the liquid level state satisfies a predetermined liquid level state, and after the step of cooling the coolant by the cooling device, further comprises:
and when the preset liquid level state is a low liquid level state, alarming and reminding are carried out to prompt the addition of the secondary refrigerant.
14. The method as claimed in claim 10, wherein the step of activating the driving device and the cooling device when the liquid level state satisfies a predetermined liquid level state, and after the step of cooling the coolant by the cooling device, further comprises:
and when the current liquid level state is detected to be a liquid level empty state, closing the driving device and the refrigerating device, and giving an alarm.
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| CN114963610A (en) * | 2022-05-26 | 2022-08-30 | 中元汇吉生物技术股份有限公司 | Reagent refrigerating system and control method and analyzer thereof |
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Address after: 6 / F, no.1-400000, industrial park, Taikang District, Chongqing Applicant after: Zhongyuan Huiji Biotechnology Co.,Ltd. Address before: 6 / F, no.1-400000, industrial park, Taikang District, Chongqing Applicant before: CHONGQING ZHONGYUAN HUIJI BIOTECHNOLOGY Co.,Ltd. |
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Application publication date: 20211116 |