CN113597555B - 单源光声遥感器（ss-pars） - Google Patents

单源光声遥感器（ss-pars） Download PDF

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Publication number
CN113597555B
CN113597555B CN202080021598.6A CN202080021598A CN113597555B CN 113597555 B CN113597555 B CN 113597555B CN 202080021598 A CN202080021598 A CN 202080021598A CN 113597555 B CN113597555 B CN 113597555B
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imaging
excitation
sample
interrogation
optical
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CN113597555A (zh
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帕尔森·哈吉瑞泽
科文·贝尔
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E Lume Sony Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002—Operational features of endoscopes
    • A61B1/00004—Operational features of endoscopes characterised by electronic signal processing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163—Optical arrangements
    • A61B1/00172—Optical arrangements with means for scanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0615—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements for radial illumination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room
    • A61B5/0035—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring blood gases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1702—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00112—Connection or coupling means
    • A61B1/00117—Optical cables in or with an endoscope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/02042—Determining blood loss or bleeding, e.g. during a surgical procedure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1702—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids
    • G01N2021/1706—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids in solids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/068—Optics, miscellaneous
    • G01N2201/0683—Brewster plate; polarisation controlling elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/08—Optical fibres; light guides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Signal Processing (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
CN202080021598.6A 2019-03-15 2020-03-03 单源光声遥感器（ss-pars） Active CN113597555B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962818967P 2019-03-15 2019-03-15
US62/818,967 2019-03-15
PCT/IB2020/051804 WO2020188386A1 (en) 2019-03-15 2020-03-03 Single source photoacoustic remote sensing (ss-pars)

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CN113597555A CN113597555A (zh) 2021-11-02
CN113597555B true CN113597555B (zh) 2024-07-19

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US (2) US11564578B2 (enExample)
EP (1) EP3938772B1 (enExample)
JP (1) JP2022524857A (enExample)
CN (1) CN113597555B (enExample)
AU (1) AU2020243527B2 (enExample)
CA (1) CA3132432A1 (enExample)
DE (1) DE202020102104U1 (enExample)
IL (1) IL286185B1 (enExample)
WO (1) WO2020188386A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020102475A1 (en) * 2018-11-14 2020-05-22 Mstatt Llc Method for optically detecting tooth mineralization
CN112740066B (zh) * 2019-05-31 2023-08-04 深圳市速腾聚创科技有限公司 一种多脉冲激光雷达系统抗干扰处理方法及装置
CN115004005A (zh) * 2019-12-19 2022-09-02 易路美索尼克股份有限公司 光声远程感测（pars）和相关的使用方法
CN114018827A (zh) * 2021-09-26 2022-02-08 宝宇(武汉)激光技术有限公司 一种基于剪切散斑干涉的激光超声无损检测设备及方法
CN118679369A (zh) * 2022-01-06 2024-09-20 杜克大学 用于光声显微镜的系统和方法
EP4662479A1 (en) 2023-02-08 2025-12-17 Illumisonics Inc. Photon absorption remote sensing system for histological assessment of tissues
CN116158737A (zh) * 2023-04-20 2023-05-26 中国医学科学院北京协和医院 一种光声成像技术评估血氧饱和度的方法及装置
CN116584880A (zh) * 2023-05-26 2023-08-15 中南大学 基于光学多模态的消化道肿瘤光动力诊疗一体化内窥探头

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5991479A (en) 1984-05-14 1999-11-23 Kleinerman; Marcos Y. Distributed fiber optic sensors and systems
JPH0827264B2 (ja) 1988-09-21 1996-03-21 工業技術院長 マルチ変調周波数による光音響撮像方法
US5479259A (en) 1991-05-20 1995-12-26 Hitachi, Ltd. Method and apparatus for detecting photoacoustic signal
US5517303A (en) * 1993-03-08 1996-05-14 Dylor Corporation Coherence selective sensor system
US5615675A (en) 1996-04-19 1997-04-01 Regents Of The University Of Michigan Method and system for 3-D acoustic microscopy using short pulse excitation and 3-D acoustic microscope for use therein
US6016202A (en) 1997-06-30 2000-01-18 U.S. Philips Corporation Method and apparatus for measuring material properties using transient-grating spectroscopy
US6256100B1 (en) 1998-04-27 2001-07-03 Active Impulse Systems, Inc. Method and device for measuring the thickness of thin films near a sample's edge and in a damascene-type structure
US20040154402A1 (en) * 1998-06-30 2004-08-12 Lockheed Martin Corporation Remote laser beam delivery system and method for use with a robotic positioning system for ultrasonic testing purposes
US6078397A (en) 1999-04-20 2000-06-20 National Research Council Method and apparatus for mapping the wall thickness of tubes during production
JP3288672B2 (ja) * 2000-02-17 2002-06-04 科学技術振興事業団 試料の物理的性質の測定装置
US6678413B1 (en) * 2000-11-24 2004-01-13 Yiqing Liang System and method for object identification and behavior characterization using video analysis
GB0123640D0 (en) 2001-09-19 2003-04-09 Matra Bae Dynamics Uk Ltd Multiple pulse generation
JP2003215110A (ja) * 2002-01-17 2003-07-30 Nippon Steel Corp レーザ超音波検査装置及びレーザ超音波検査方法
WO2004086965A1 (en) 2003-04-01 2004-10-14 Glucon Inc. Photoacoustic assay method and apparatus
DE10333770A1 (de) * 2003-07-22 2005-02-17 Carl Zeiss Meditec Ag Verfahren zur Materialbearbeitung mit Laserimpulsen grosser spektraler Bandbreite und Vorrichtung zur Durchführung des Verfahrens
US7364543B2 (en) * 2004-03-23 2008-04-29 California Institute Of Technology Paired angled rotation scanning probes and methods of use
US7089796B2 (en) * 2004-03-24 2006-08-15 Hrl Laboratories, Llc Time-reversed photoacoustic system and uses thereof
US7387027B2 (en) * 2004-07-23 2008-06-17 Massachusetts Institute Of Technology Characterization of materials with optically shaped acoustic waveforms
US20060184042A1 (en) 2005-01-22 2006-08-17 The Texas A&M University System Method, system and apparatus for dark-field reflection-mode photoacoustic tomography
WO2006084279A2 (en) * 2005-02-04 2006-08-10 University Of Florida Research Foundation, Inc. Single fiber endoscopic full-field optical coherence tomography (oct) imaging probe
US20060262316A1 (en) 2005-05-20 2006-11-23 Baney Douglas M System and method for interferometric laser photoacoustic spectroscopy
EP2018546A1 (en) 2006-05-10 2009-01-28 National Research Council of Canada Method of assessing bond integrity in bonded structures
US8501099B2 (en) 2006-07-11 2013-08-06 The Curators Of The University Of Missouri Photo-acoustic detection device and method
CN101626719B (zh) 2006-09-26 2012-07-18 俄勒冈健康与科学大学 体内结构和流动成像
US20080123083A1 (en) 2006-11-29 2008-05-29 The Regents Of The University Of Michigan System and Method for Photoacoustic Guided Diffuse Optical Imaging
EP3229010A3 (en) 2007-10-25 2018-01-10 Washington University in St. Louis Confocal photoacoustic microscopy with optical lateral resolution
JP2010185772A (ja) * 2009-02-12 2010-08-26 Osaka Univ センサー素子およびそれを備えたセンサー装置
CN101526483A (zh) 2009-04-13 2009-09-09 电子科技大学 一种利用光声干涉成像进行无损检测方法
US9335605B2 (en) 2010-01-25 2016-05-10 Washington University Iteration of optical time reversal by ultrasonic encoding in biological tissue
DE102010012809A1 (de) 2010-03-23 2011-09-29 Carl Zeiss Meditec Ag Vorrichtung und Verfahren zur dreidimensionalen optischen Temperaturmessung im Auge
US9999354B2 (en) * 2011-01-21 2018-06-19 National Research Council Of Canada Biological tissue inspection method and system
US8997572B2 (en) 2011-02-11 2015-04-07 Washington University Multi-focus optical-resolution photoacoustic microscopy with ultrasonic array detection
US9442095B2 (en) 2011-06-15 2016-09-13 Northwestern University Optical coherence photoacoustic microscopy
JP5832182B2 (ja) 2011-07-19 2015-12-16 キヤノン株式会社 音響信号受信装置およびイメージング装置
WO2013023210A1 (en) * 2011-08-11 2013-02-14 University Of Washington Through Its Center For Commercialization Methods and systems for integrated imaging using optical coherence tomography and photoacoustic imaging
JP2013089680A (ja) 2011-10-14 2013-05-13 Canon Inc レーザー装置およびその制御方法
US8885155B2 (en) * 2012-04-30 2014-11-11 Covidien Lp Combined light source photoacoustic system
KR101352769B1 (ko) 2012-05-09 2014-01-22 서강대학교산학협력단 배경과 관심조직을 구별하는 방법 및 장치
US9335267B2 (en) * 2012-07-09 2016-05-10 The United States Of America As Represented By The Secretary Of The Army Near-IR laser-induced vibrational overtone absorption systems and methods for material detection
WO2014027316A2 (en) 2012-08-14 2014-02-20 Koninklijke Philips N.V. Compact laser and efficient pulse delivery for photoacoustic imaging
JP5840181B2 (ja) 2012-08-17 2016-01-06 富士フイルム株式会社 光音響画像生成装置及び方法
WO2014036405A2 (en) 2012-08-30 2014-03-06 The Board Of Regents Of The University Of Texas System Method and apparatus for ultrafast multi-wavelength photothermal optical coherence tomography (oct)
EP2951647B1 (en) 2012-09-25 2025-06-18 Asociación centro de Investigación Cooperativa en Nanociencias, CIC Nanogune Synthetic optical holography
WO2014062529A1 (en) 2012-10-15 2014-04-24 Josh Hogan Enhanced oct measurement and imaging apparatus and method
CN103048271A (zh) 2012-12-21 2013-04-17 江西科技师范大学 组合光声成像和光学相干层析成像的便携式双模态成像方法及其系统
EP2774530B1 (de) 2013-03-04 2019-07-10 Medizinisches Laserzentrum Lübeck GmbH Verfahren zur photoakustischen Tomographie
US20150371401A1 (en) 2013-03-13 2015-12-24 University Of Washington Methods and Systems for Imaging Tissue Motion Using Optical Coherence Tomography
WO2014168930A1 (en) 2013-04-09 2014-10-16 University Of Washington Through Its Center For Commercialization Methods and systems for determining hemodynamic properties of a tissue
KR101543872B1 (ko) * 2013-11-20 2015-08-11 주식회사 포스코 복수의 레이저 간섭계를 가지는 레이저 초음파 장치 및 이를 이용한 신호 처리 방법
WO2015077088A1 (en) 2013-11-22 2015-05-28 Massachusetts Institute Of Technology System and method for non-contact ultrasound
JP2015104476A (ja) 2013-11-29 2015-06-08 船井電機株式会社 光音響画像化装置
KR102270798B1 (ko) 2013-12-16 2021-06-30 삼성메디슨 주식회사 광음향 프로브 및 광음향 진단 장치
US9995674B2 (en) 2013-12-26 2018-06-12 The United States Of America As Represented By The Administrator Of Nasa. Photoacoustic chemical detector
WO2015103550A1 (en) * 2014-01-03 2015-07-09 The Regents Of The University Of Michigan Photoacoustic physio-chemical tissue analysis
JP6327900B2 (ja) 2014-03-24 2018-05-23 キヤノン株式会社 被検体情報取得装置、乳房検査装置および装置
US10371668B2 (en) * 2014-07-11 2019-08-06 Vanderbilt University Apparatus and methods for probing a material as a function of depth using depth-dependent second harmonic generation
US10117583B2 (en) 2014-10-22 2018-11-06 illumiSonics, Inc. Photoacoustic remote sensing (PARS)
DE102015116435A1 (de) * 2015-09-29 2017-03-30 Carl Zeiss Microscopy Gmbh Hochauflösende Scanning-Mikroskopie mit der Unterscheidung mindestens zweier Spektralbereiche
US10327646B2 (en) * 2016-02-02 2019-06-25 Illumisonics Inc. Non-interferometric photoacoustic remote sensing (NI-PARS)
WO2018065958A1 (en) * 2016-10-06 2018-04-12 Livspek Medical Technologies Inc. Method and apparatus for a spectral detector for noninvasive detection and monitoring of a variety of biomarkers and other blood constituents in the conjunctiva
US10627338B2 (en) * 2017-03-23 2020-04-21 Illumisonics Inc. Camera-based photoacoustic remote sensing (C-PARS)
CN109363639A (zh) 2018-11-13 2019-02-22 东北大学秦皇岛分校 一种基于光程调制结合灵敏度补偿的高速非接触光声成像系统

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CN113597555A (zh) 2021-11-02
EP3938772B1 (en) 2025-07-16
IL286185B1 (en) 2026-04-01
US20230225618A1 (en) 2023-07-20
US11564578B2 (en) 2023-01-31
WO2020188386A1 (en) 2020-09-24
EP3938772A1 (en) 2022-01-19
JP2022524857A (ja) 2022-05-10
AU2020243527A1 (en) 2021-11-11
IL286185A (en) 2021-10-31
EP3938772A4 (en) 2022-11-30
US11950882B2 (en) 2024-04-09
CA3132432A1 (en) 2020-09-24
AU2020243527B2 (en) 2025-10-09
DE202020102104U1 (de) 2020-05-19
US20210199566A1 (en) 2021-07-01

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