CN113597316A - 脂性药物制剂及其应用 - Google Patents

脂性药物制剂及其应用 Download PDF

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CN113597316A
CN113597316A CN202080021973.7A CN202080021973A CN113597316A CN 113597316 A CN113597316 A CN 113597316A CN 202080021973 A CN202080021973 A CN 202080021973A CN 113597316 A CN113597316 A CN 113597316A
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lipid
pharmaceutical preparation
preparation
lipid pharmaceutical
pain
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CN113597316B (zh
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张洁
唐培克
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Huzhou Enowei New Pharmaceutical Preparation Co ltd
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/47—Quinolines; Isoquinolines
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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Abstract

一种脂性药物制剂及其应用。该脂性药物制剂包括局部麻醉药和脂类物质，局部麻醉药在脂性药物制剂中的质量百分比为2％‑50％，局部麻醉药为利多卡因、丁卡因、布比卡因、阿替卡因、辛可卡因、地布卡因、依替卡因、左布比卡因、甲哌卡因、丙胺卡因、罗哌卡因、三甲卡因、苯佐卡因或普鲁卡因；脂类物质在脂性药物制剂中的质量百分比为30％‑98％；所述脂性药物制剂中各组分的质量百分比之和为100％。在许多镇痛应用中，该脂性药物制剂，能够获得12、24、36、48、72小时，甚至更长时间的连续安全镇痛效果。

Description

PCT国内申请，说明书已公开。

Claims (20)

  1. PCT国内申请，权利要求书已公开。
CN202080021973.7A 2019-04-15 2020-04-15 脂性药物制剂及其应用 Active CN113597316B (zh)

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CN2019102999499 2019-04-15
PCT/CN2020/084832 WO2020211762A1 (zh) 2019-04-15 2020-04-15 脂性药物制剂及其应用

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CN111840553A (zh) * 2019-04-15 2020-10-30 湖州依诺唯新药物制剂有限公司 脂性药物制剂及其应用

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CN115252557B (zh) * 2022-09-01 2023-06-02 广东嘉博制药有限公司 一种罗哌卡因多囊脂质体制剂的制备方法

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EP3957328A4 (en) 2023-03-22
CN113597316B (zh) 2023-11-24
CN111840553A (zh) 2020-10-30
EP3957328A1 (en) 2022-02-23
US20220193014A1 (en) 2022-06-23
WO2020211762A1 (zh) 2020-10-22

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