CN113574175A - 基因敲入方法、基因敲入细胞制作方法、基因敲入细胞、癌变风险评价方法、癌细胞制造方法和用于在它们中使用的试剂盒 - Google Patents
基因敲入方法、基因敲入细胞制作方法、基因敲入细胞、癌变风险评价方法、癌细胞制造方法和用于在它们中使用的试剂盒 Download PDFInfo
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| PCT/JP2020/039169 WO2021171688A1 (ja) | 2020-02-26 | 2020-10-16 | 遺伝子ノックイン方法、遺伝子ノックイン細胞作製方法、遺伝子ノックイン細胞、がん化リスク評価方法、がん細胞製造方法、及びこれらに用いるためのキット |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106191116A (zh) * | 2016-08-22 | 2016-12-07 | 西北农林科技大学 | 基于CRISPR/Cas9的外源基因敲入整合系统及其建立方法和应用 |
| US20170051354A1 (en) * | 2014-04-28 | 2017-02-23 | Sigma-Aldrich Co. Llc | Epigenetic modification of mammalian genomes using targeted endonucleases |
| US20180179525A1 (en) * | 2016-09-07 | 2018-06-28 | Flagship Pioneering, Inc. | Methods and compositions for modulating gene expression |
| US20190169653A1 (en) * | 2016-08-10 | 2019-06-06 | National University Corporation Tokyo Medical And Dental University | Method for preparing gene knock-in cells |
| US20190225989A1 (en) * | 2018-01-19 | 2019-07-25 | Institute of Hematology and Blood Disease Hospital, CAMS & PUMC | Gene knockin method and kit for gene knockin |
| CN110312799A (zh) * | 2016-08-17 | 2019-10-08 | 博德研究所 | 新型crispr酶和系统 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| AU2003252483A1 (en) * | 2003-07-08 | 2005-01-21 | Japan Science And Technology Corporation | Method and system of constructing transgenic organism |
| JP5900942B2 (ja) * | 2013-11-06 | 2016-04-06 | 国立大学法人広島大学 | 核酸挿入用ベクター |
| JP6500293B2 (ja) | 2015-11-25 | 2019-04-17 | 国立大学法人群馬大学 | Ｄｎａメチル化編集用キットおよびｄｎａメチル化編集方法 |
| JP6946133B2 (ja) | 2017-09-27 | 2021-10-06 | 株式会社レナテック | がんリスク評価方法及びがんリスク評価システム |
| CA3119301A1 (en) * | 2018-11-08 | 2020-05-14 | National University Corporation Tokai National Higher Education And Research System | Gene therapy employing genome editing with single aav vector |
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- 2020-10-16 WO PCT/JP2020/039169 patent/WO2021171688A1/ja not_active Ceased
- 2020-10-16 US US17/267,224 patent/US20220112509A1/en not_active Abandoned
- 2020-10-16 EP EP20848686.0A patent/EP4112719A1/en not_active Withdrawn
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170051354A1 (en) * | 2014-04-28 | 2017-02-23 | Sigma-Aldrich Co. Llc | Epigenetic modification of mammalian genomes using targeted endonucleases |
| US20190169653A1 (en) * | 2016-08-10 | 2019-06-06 | National University Corporation Tokyo Medical And Dental University | Method for preparing gene knock-in cells |
| CN110312799A (zh) * | 2016-08-17 | 2019-10-08 | 博德研究所 | 新型crispr酶和系统 |
| CN106191116A (zh) * | 2016-08-22 | 2016-12-07 | 西北农林科技大学 | 基于CRISPR/Cas9的外源基因敲入整合系统及其建立方法和应用 |
| US20180179525A1 (en) * | 2016-09-07 | 2018-06-28 | Flagship Pioneering, Inc. | Methods and compositions for modulating gene expression |
| US20190225989A1 (en) * | 2018-01-19 | 2019-07-25 | Institute of Hematology and Blood Disease Hospital, CAMS & PUMC | Gene knockin method and kit for gene knockin |
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| US20220112509A1 (en) | 2022-04-14 |
| JPWO2021171688A1 (https=) | 2021-09-02 |
| WO2021171688A1 (ja) | 2021-09-02 |
| EP4112719A1 (en) | 2023-01-04 |
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