CN113533006A - Full-automatic dyeing machine capable of quickly preparing slices - Google Patents
Full-automatic dyeing machine capable of quickly preparing slices Download PDFInfo
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- CN113533006A CN113533006A CN202110848025.7A CN202110848025A CN113533006A CN 113533006 A CN113533006 A CN 113533006A CN 202110848025 A CN202110848025 A CN 202110848025A CN 113533006 A CN113533006 A CN 113533006A
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- 238000004043 dyeing Methods 0.000 title claims abstract description 100
- 230000007246 mechanism Effects 0.000 claims abstract description 75
- 239000011521 glass Substances 0.000 claims abstract description 52
- 238000012546 transfer Methods 0.000 claims abstract description 14
- 239000012528 membrane Substances 0.000 claims description 37
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims description 11
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- 241001330002 Bambuseae Species 0.000 claims description 11
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims description 11
- 239000011425 bamboo Substances 0.000 claims description 11
- 239000007788 liquid Substances 0.000 claims description 9
- 238000004140 cleaning Methods 0.000 claims description 8
- 230000004907 flux Effects 0.000 claims description 7
- 239000010902 straw Substances 0.000 claims description 6
- 238000013461 design Methods 0.000 claims description 5
- 238000012545 processing Methods 0.000 claims description 5
- 239000002699 waste material Substances 0.000 claims description 5
- 238000003860 storage Methods 0.000 claims description 4
- 238000009434 installation Methods 0.000 claims description 3
- 238000004321 preservation Methods 0.000 claims description 2
- 238000002604 ultrasonography Methods 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims 2
- 238000000034 method Methods 0.000 abstract description 18
- 230000008569 process Effects 0.000 abstract description 10
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Images
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
Abstract
The invention discloses a full-automatic rapid film-making dyeing machine which comprises an automatic film-making mechanism, a multi-dyeing-cylinder automatic dip dyeing mechanism and an automatic transfer mechanism, wherein the automatic film-making mechanism comprises a sample glass carrier drawer, a filter cup film carrier drawer, a slide frame glass carrier drawer and a slide glass carrier drawer, a sample bottle operation module is arranged above the sample glass carrier drawer, a filter cup film carrier operation module is arranged above the filter cup film carrier glass drawer, a clamping jaw assembly is arranged on one side of the slide frame glass carrier drawer, and a film-making module is arranged on one side of the clamping jaw assembly. In this full-automatic dyeing machine of making film fast, only need once only load the equipment with sample and film-making consumptive material on, the machine realizes discerning, beating the sign indicating number, sweeping sign indicating number, film-making, racking, full flow processes such as transfer, dyeing to the sample in batches automatically to have the mounting and shift the interface, can with mounting equipment online operation, will dye the appearance piece of finished colour and carry out the mounting and handle in the mounting equipment. The whole process does not need manual intervention.
Description
Technical Field
The invention relates to the technical field of slide processing equipment, in particular to a full-automatic rapid slide-making dyeing machine.
Background
The extraction of human exfoliated cells and observation of the morphological and structural changes thereof under a microscope are important means for diagnosing human diseases, and the process of uniformly spreading a human exfoliated cell monolayer on a glass slide and then dyeing is one of the key processes. Limited by technical means, realization cost and other factors, most of the current flaking and dyeing machines adopt sedimentation type flaking and drop dyeing methods, and have the following technical defects:
1. sedimentation type slide making mainly depends on the external force action of gravity or centrifugal force, so that slide making components are settled on a glass slide, the components and the quantity left on the glass slide cannot be controlled, the depth of field under a sample lens is large, cells are overlapped, still interference components such as mucus, tissue blocks, scraps, sundries and the like exist, the observation is not easy to occur under a microscope, and missed diagnosis and misdiagnosis are easy to occur;
2. sedimentation type flaking is mainly used for flaking cervical exfoliated cells, and has poor effects on samples such as urine, sputum, hydrothorax and ascites.
3. The drop dyeing method is to drop different dyeing liquids into a part of area of a sample wafer in a time-sharing manner, and because the amount of the dyeing liquid contacting the sample wafer is small and the dyeing cannot be completely realized according to a standard dyeing process, insufficient and uneven dyeing is easily caused, visual disturbance is easily caused to diagnosticians, and missed diagnosis and misdiagnosis are further generated;
4. the sedimentation type flaking and drop dyeing method dyeing mode is limited by the implementation method, can not be connected with subsequent piece sealing equipment, can not realize an automatic process, and can only be manually transferred to a piece sealing transfer mechanism or manual piece sealing, so that the working time is prolonged, and the working efficiency is reduced.
5. At present, the dip dyeing equipment mainly depends on normal-temperature normal molecular motion to carry out component replacement, and the time consumption is long.
6. Manual intervention is needed in the sedimentation type flaking and drop dyeing method dyeing working process, the needed material consumption is more, and the working cost is increased.
Disclosure of Invention
The invention aims to provide a full-automatic rapid flaking and dyeing machine, which aims to solve the problems in the background technology.
In order to achieve the purpose, the invention provides a full-automatic rapid film-making dyeing machine which comprises an automatic film-making mechanism, a multi-dyeing-cylinder automatic dip dyeing mechanism and an automatic transfer mechanism, wherein the automatic film-making mechanism comprises a sample glass carrier drawer, a filter cup film carrier drawer, a slide frame glass carrier drawer and a slide glass carrier drawer, a sample bottle operation module is arranged above the sample glass carrier drawer, the filter cup film carrier operation module is arranged above the filter cup film carrier drawer, a clamping jaw assembly is arranged on one side of the slide frame glass carrier drawer, a film-making module is arranged on one side of the clamping jaw assembly, an insert module is arranged above the film-making module, the automatic film-making mechanism comprises a first lifting module arranged above the automatic film-making mechanism, and the automatic film-making mechanism further comprises a preservation liquid cylinder combined machine glass carrier arranged below the automatic film-making mechanism; the automatic dip-dyeing mechanism of the multi-dyeing cylinder comprises a plurality of dyeing cylinders which are sequentially placed, a cleaning cylinder, a baking cylinder and a manual unloading cylinder are sequentially placed on the outer side of each dyeing cylinder, and the automatic dip-dyeing mechanism of the multi-dyeing cylinder comprises a second lifting module which is arranged above the multi-dyeing cylinder; the automatic dip-dyeing mechanism of many dye vats includes the transverse guide of top installation, longitudinal rail is installed at the transverse guide both ends, the top of module is lifted by crane to the second passes through motor and actuating mechanism and moves on transverse guide, the transverse guide both ends are passed through motor and actuating mechanism and are removed along longitudinal rail.
Preferably, a slide placing opening is formed in the position, close to the slide glass grid drawer, of the outer wall of the automatic slide making mechanism, and a slide rack taking-out opening is formed in the position, close to the manual unloading cylinder, of the outer wall of the multi-staining-cylinder automatic dip-staining mechanism.
As preferred, the clamping jaw subassembly is including the horizontal electric putter, vertical electric putter and the lift that set gradually, vertical electric putter installs on horizontal electric putter's output, the lift is installed on vertical electric putter's output, the output end of lift can be changeed and have first rotating electrical machines according to that, the centre gripping arm is installed to first rotating electrical machines's output, second rotating electrical machines is installed to one side of first rotating electrical machines, slide frame clamping bar is installed to the output of second rotating electrical machines, the centre gripping arm is two poles of symmetry and parallel arrangement, and the inboard of pole is seted up flutedly, L clamp head is installed at the both ends of slide frame clamping bar.
As preferred, the film-making module includes the fixing base, the slide station is installed on the inboard upper portion of fixing base, the below of slide station is provided with filter cup membrane section of thick bamboo station, the below of fixing base is provided with the straw, the suction groove is installed at the top of straw, filter cup membrane cover constant head tank has been seted up to top one side of fixing base, the lift is installed to one side of filter cup membrane section of thick bamboo station, filter cup membrane section of thick bamboo station can go up and down through the lift.
Preferably, the automatic slide making mechanism is provided with a code mutual identification mechanism of the sample and the slide glass, a mechanism capable of automatically identifying the sample code and printing the code on the slide glass can also automatically identify and extract the corresponding sample according to the code on the slide glass.
Preferably, the automatic dip dyeing mechanism is further provided with devices for ultrasonic treatment, temperature rise and the like, so that the dyeing treatment time is shortened.
Preferably, the instruments such as the samples, the slide making consumables and the slide racks are designed by adopting a design structure of desktop arrangement and drawer storage, and are designed according to one or more standard fluxes, wherein one standard flux can be designed in a range of 2-80 samples.
Preferably, in the automatic slide making mechanism, the slide is transferred from the slide glass rack drawer to the slide making station and from the slide making station to the slide rack by adopting a one-dimensional horizontal pushing structure, so that the reliability of the transfer is ensured.
Preferably, a waste bin hopper is arranged below the tabletting module.
Preferably, the number of the cleaning cylinders and the number of the baking cylinders are at least two, two ends of the dyeing cylinder are respectively provided with an automatic loading cylinder position, a manual unloading cylinder position and a sealing piece automatic transfer cylinder position, and a counting scanner is arranged above the inside of the multi-dyeing-cylinder automatic dip dyeing mechanism.
Compared with the prior art, the invention has the beneficial effects that:
1. in this full-automatic dyeing machine of making film fast, only need once only load the equipment with sample and film-making consumptive material on, the machine realizes discerning, beating the sign indicating number, sweeping sign indicating number, film-making, racking, full flow processes such as transfer, dyeing to the sample in batches automatically to have the mounting and shift the interface, can with mounting equipment online operation, will dye the appearance piece of finished colour and carry out the mounting and handle in the mounting equipment. The whole process does not need manual intervention.
2. In the full-automatic rapid slide-making dyeing machine, slide loading modes are different during slide making, the slide can be loaded in a whole box, codes on a sample bottle are grabbed and scanned, then the codes are printed on the slide for slide making, so that the slide codes and the sample codes can be ensured to be consistent, the equipment is automatically completed during operation, and the sequence of the arranged samples is not required to be concerned during loading.
3. In this full-automatic quick film-making dyeing machine, have full-automatic high flux and make a film dyeing function fast in batches, can with mounting equipment online operation simultaneously, whole journey need not artificial intervention, film-making dyeing effect is good, work efficiency is high, can effectively reduce use cost.
4. The slide making module of the full-automatic rapid slide making and dyeing machine adopts a slide making structure, filters out interference components larger than and smaller than a target through a screening filter membrane with various apertures, and only keeps the target components on a glass slide; secondly, the quantity of the extracted target components is controlled through pressure monitoring, and the effectiveness of tabletting is ensured; thirdly, transferring the effective components in a membrane pressing mode, ensuring that the effective components on the sample wafer are uniformly spread in a single layer, and effectively reducing the probability of false positive and false negative of diagnosis; the product can be used for the examination of exfoliated cells in body fluids such as urine, hydrothorax, ascites and sputum and cervical exfoliated cells, and can be widely used for the screening and daily examination of mass diseases such as bladder cancer, lung cancer and cervical cancer.
5. The dyeing bin of the full-automatic rapid slice-making dyeing machine adopts a multi-cylinder dip dyeing mode, reduces dyeing processing time by means of ultrasound, temperature rise and the like, can rapidly realize the dyeing process of whole-process standardization, has sufficient and uniform dyeing, ensures the dyeing effect of sample wafers, and reduces the missed diagnosis and misdiagnosis probability of diagnosticians.
6. In the full-automatic rapid slice-making dyeing machine, the multi-dyeing-cylinder automatic dip dyeing mechanism adopts a multi-task simultaneous operation design scheme which can be edited by a user, can be suitable for different dyeing methods and samples, effectively improves the application range and the working efficiency of products, can be integrally operated on line with a slice-making bin and a dyeing bin of the full-automatic rapid slice-making dyeing machine, can be independently operated, can meet various requirements of different users, and is convenient to use because the loading and unloading of samples, consumables, appliances and the like adopt an integrated easy-operation structural design.
Drawings
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a schematic view of an automatic sheet-making mechanism according to the present invention;
FIG. 3 is a second schematic view of the automatic sheet-making mechanism of the present invention;
FIG. 4 is a schematic structural view of an automatic dip-dyeing mechanism of a multi-dyeing cylinder in the invention;
figure 5 is a schematic view of the jaw assembly of the present invention.
FIG. 6 is a schematic structural diagram of a sheet-making module according to the present invention;
FIG. 7 is a schematic view of the internal assembly of the present invention;
FIG. 8 is a schematic view of the vertical position of the slide holder of the present invention.
The various reference numbers in the figures mean:
1. an automatic sheet making mechanism; 11. a sample carrier drawer; 12. a filter cup membrane cartridge grid drawer; 13. slide rack grid drawer; 14. a sample bottle operating module; 15. a filter cup membrane cylinder operation module; 16. a jaw assembly; 161. a transverse electric push rod; 162. a longitudinal electric push rod; 163. an elevator; 164. a first rotating electrical machine; 165. a clamp arm; 166. a second rotating electrical machine; 167. a slide rack clamping bar; 17. a film making module; 171. a fixed seat; 172. a slide station; 173. a filter cup membrane cylinder station; 174. a straw; 1741. a liquid suction tank; 175. a filter cup membrane cylinder cover positioning groove; 18. an insert module; 19. a waste hopper; 110. a first hoisting module; 111. storing the liquid cylinder online loading grids; 112. a slide placing port; 113. a slide grid drawer; 2. a multi-dyeing-cylinder automatic dip dyeing mechanism; 21. a second hoisting module; 22. a counting scanner; 23. a dyeing vat; 231. manually loading the cylinder position; 232. automatically loading the cylinder position; 233. the sealing sheet automatically transfers the cylinder position; 24. cleaning the cylinder; 25. a baking jar; 26. manually unloading the cylinder position; 27. a slide rack take-out port; 28. a transverse guide rail; 29. a longitudinal guide rail.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations and positional relationships based on those shown in the drawings, and are used only for convenience of description and simplicity of description, and do not indicate or imply that the equipment or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be considered as limiting the present invention.
Furthermore, the terms "first", "second", "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, the definitions of "first", "second" and "third" features may explicitly or implicitly include one or more of such features. In the description of the present invention, "a plurality" means two or more unless specifically limited otherwise.
The invention provides a full-automatic rapid slide-making dyeing machine, as shown in figures 1-8, comprising an automatic slide-making mechanism 1, a multi-dyeing-cylinder automatic dip dyeing mechanism 2 and an automatic transfer mechanism, wherein the automatic slide-making mechanism 1 comprises a sample slide grid drawer 11, a filter cup film slide grid drawer 12, a slide frame slide grid drawer 13 and a slide glass slide grid drawer 113, the slide glass slide grid drawer 113 is used for placing a slide to be processed, a sample bottle operating module 14 is arranged above the sample slide grid drawer 11, a mechanical gripper structure is adopted in the embodiment, which can grip and move a sample bottle, a filter cup film cylinder operating module 15 is arranged above the filter cup film cylinder slide grid drawer 12, a mechanical gripper structure is also adopted in the embodiment, which grips and moves the filter cup film cylinder, a clamping jaw assembly 16 is arranged on one side of the slide frame slide grid drawer 13, and is used for moving and turning the slide frame slide grid drawer 13, one side of the clamping jaw component 16 is provided with a slide making module 17 for transferring cell tissues, an inserting sheet module 18 is arranged above the slide making module 17 and used for pushing a slide into the slide making module 17, the inserting sheet module 18 is driven to move by a horizontal cylinder, the inserting sheet module 18 comprises push plates positioned at two sides of the slide making module 17, the two push plates are driven to move by the cylinder, and then the slide is pushed into the slide making module 17, the automatic slide making mechanism 1 comprises a first lifting module 110 arranged above, the automatic slide making mechanism 1 further comprises a storage liquid cylinder connected machine carrier grid 111 arranged below and used for placing a made slide rack; the multi-dyeing-cylinder automatic dip-dyeing mechanism 2 comprises a plurality of dyeing cylinders 23 which are sequentially placed, a cleaning cylinder 24, a baking cylinder 25 and a manual unloading cylinder position 26 are sequentially placed on the outer sides of the dyeing cylinders 23, and the multi-dyeing-cylinder automatic dip-dyeing mechanism 2 comprises a second lifting module 21 arranged above the multi-dyeing-cylinder automatic dip-dyeing mechanism; the automatic dip-dyeing mechanism 2 of many dye vats includes the transverse guide 28 of top installation, longitudinal rail 29 is installed at transverse guide 28 both ends, the second lifts by crane the top of module 21 and passes through motor and actuating mechanism and move on transverse guide 28, the transverse guide 28 both ends are passed through motor and actuating mechanism and are removed along longitudinal rail 29, thereby make the second lift by crane module 21 and can remove at will, automatic film-making mechanism 1 also installs the same structure, can lift by crane module 110 with first and remove at will.
In this embodiment, a slide placing port 112 is provided on the outer wall of the automatic slide making mechanism 1 near the slide glass grid drawer 13 for placing a slide glass therein, and a slide rack taking-out port 27 is provided on the outer wall of the multi-staining-cylinder automatic dip-staining mechanism 2 near the manual unloading cylinder position 26 for taking out a prepared and stained slide glass.
Specifically, the clamping jaw assembly 16 includes a transverse electric push rod 161, a longitudinal electric push rod 162 and a lifter 163 which are sequentially arranged, the longitudinal electric push rod 162 is installed at the output end of the transverse electric push rod 161, the lifter 163 is installed at the output end of the longitudinal electric push rod 162, the output end of the lifter 163 can be rotated to have a first rotating motor 164, the output end of the first rotating motor 164 is provided with a clamping arm 165, one side of the first rotating motor 164 is provided with a second rotating motor 166, the output end of the second rotating motor 166 is provided with a slide frame clamping rod 167, the clamping arm 165 is two rods which are symmetrically and parallelly arranged, the inner side of each rod is provided with a groove, and two ends of the slide frame clamping rod 167 are provided with L-shaped clamping heads.
Further, the slide making module 17 includes a fixing seat 171, a slide station 172 is installed on the upper portion of the inner side of the fixing seat 171, a filter cup membrane cylinder station 173 is arranged below the slide station 172, a suction pipe 174 is arranged below the fixing seat 171, a liquid suction groove 1741 is installed at the top of the suction pipe 174, a filter cup membrane cylinder cover positioning groove 175 is formed in one side of the top of the fixing seat 171, a lifter is installed on one side of the filter cup membrane cylinder station 173, and the filter cup membrane cylinder station 173 can be lifted through the lifter.
Further, the automatic slide making mechanism 1 is provided with a code mutual searching and identifying mechanism for the sample and the slide glass, a mechanism capable of automatically identifying the sample code and printing the code on the slide glass can also automatically identify and extract the corresponding sample according to the code on the slide glass.
Furthermore, the automatic dip dyeing mechanism 2 is also provided with devices for ultrasonic treatment, temperature rise and the like, so that the dyeing treatment time is shortened.
Furthermore, the instruments such as the sample, the slide making consumables and the slide rack are designed by adopting a design structure of desktop discharge and drawer storage according to one or more standard fluxes, and one standard flux can be designed in the range of 2-80 samples.
Further, in the automatic slide making mechanism 1, the slide is transferred from the slide glass grid drawer 113 to the slide making station and from the slide making station to the slide rack by adopting a one-dimensional horizontal pushing structure, so that the transfer reliability is ensured.
Further, a waste bin hopper 19 is arranged below the sheet making module 17 and used for collecting the filter cup membrane cylinder.
Further, the number of the cleaning cylinder 24, the baking cylinder 25 and the manual unloading cylinder 26 is at least two, the cleaning cylinder, the baking cylinder and the manual unloading cylinder are used for processing in batches, one end of the dyeing cylinder 23 is provided with a manual loading cylinder 231, a slide rack to be dyed is placed into the manual loading cylinder 231, dyeing is carried out at any time, the processing efficiency is guaranteed, and the counting scanner 22 is arranged above the inside of the multi-dyeing-cylinder automatic dip-dyeing mechanism 2 and used for counting slides entering the multi-dyeing-cylinder automatic dip-dyeing mechanism 2.
The novel rapid film-making dyeing machine of this embodiment is when using:
1. firstly, preparing materials before sheet making, wherein the sample consumables are prepared, the number of sampling bottles is 30psc, manually placing the sample bottles in a sample glass slide drawer 11 according to the number sequence corresponding to the glass slide number sequence, pushing the sample bottles into an automatic sheet making mechanism 1, preparing materials for filter cup membrane cylinders, the number of the filter cup membrane cylinders is 30psc, manually placing the filter cup membrane cylinders in a filter cup membrane cylinder glass slide drawer 12, then pushing the filter cup membrane cylinders into the automatic sheet making mechanism 1, manually preparing materials for new glass slide numbers corresponding to the sample bottle number sequence, the number of the filter cup membrane cylinders is 30psc, placing the filter cup membrane cylinders in a glass slide drawer 113, and pushing the glass slide glass drawer 113 into one side of a feed inlet of a sheet making module 17;
2. the sample bottle operation module 14 operates to the sample bottle position of the sample grid drawer 11, and the filter cup membrane cylinder operation module 15 operates to the component position of the filter cup membrane cylinder grid drawer 12, so that the sample bottle and the filter cup membrane cylinder are respectively taken out.
3. The bowl membrane cartridges are placed in the bowl membrane cartridge cover positioning slots 175 of the sheeting module 17 and one bowl membrane cartridge is placed in the other bowl membrane cartridge cover positioning slots 175 in the same manner.
4. Move to one side of slide glass check drawer 13 through clamping jaw assembly 16 to rotatory to the horizontality with centre gripping arm 165, and insert in slide glass frame slide glass check drawer 13's both sides, it is fixed with outside bellied fixture block to carry out the chucking through the inboard recess of centre gripping arm 165, upwards rise with centre gripping arm 165 again, make the slide frame break away from slide glass frame slide glass check drawer 13, rotate to vertical state with centre gripping arm 165 afterwards, make the slide frame be located slide glass module 17's discharge gate one side, and the slide glass frame is the vertical state setting.
5. Move to the top of film-making module 17 through sample bottle operation module 14 centre gripping sample bottle handle, puncture the sample bottle through the sharp-pointed structure of taking on the filter bowl membrane section of thick bamboo lid to absorb cell tissue in the filter bowl membrane section of thick bamboo through straw 174, and put back the normal position of sample slide glass drawer with empty sample bottle, through the rotatory centre gripping of slide frame clamping bar 167 on the slide frame afterwards, with slide frame centre gripping in one side of film-making module 17.
6. Push slide glass check drawer 113 in proper order in slide station 172 of film-making module 17 through inserted sheet module 18, drive the rising of filter cup membrane section of thick bamboo station 173 through the lift, and then with the cell tissue suppression on the surface of slide, it can to continue to release slide station 172 of film-making module 17 and push in the slide frame through the slide of inserted sheet module 18 in with the slide frame after that, it can to put into slide frame slide glass check drawer 13 with the slide frame after that, through the repeated transfer of carrying out the histocyte on every slide of this kind of mode, the push rod is installed to one side of inserted sheet module 18, filter cup membrane section of thick bamboo after will using pushes into waste material storehouse fill 19.
7. Through first module 110 of lifting by crane with the slide frame centre gripping of film-making and hang to preserving liquid jar online machine year check 111 to lift by crane module 21 through the second in the dyeing storehouse 2 and lift by crane, thereby transport to dyeing storehouse 2 in, carry out the technique through count scanner 22 earlier in dyeing storehouse 2, wash and toast through washing jar 24 and toast jar 25 in proper order again, the slide frame after dyeing is placed in manual uninstallation jar position 26.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and the preferred embodiments of the present invention are described in the above embodiments and the description, and are not intended to limit the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (10)
1. The utility model provides a full-automatic quick film-making dyeing machine, includes automatic film-making mechanism (1), the automatic dip-dyeing mechanism of many dye vats (2), automatic transfer mechanism, its characterized in that: the automatic slide making mechanism (1) comprises a sample slide grid drawer (11), a filter cup film slide grid drawer (12), a slide frame slide grid drawer (13) and a slide glass slide grid drawer (113), a sample bottle operation module (14) is arranged above the sample slide grid drawer (11), a filter cup film slide grid operation module (15) is arranged above the filter cup film slide grid drawer (12), a clamping jaw assembly (16) is arranged on one side of the slide frame slide grid drawer (13), a slide making module (17) is arranged on one side of the clamping jaw assembly (16), an inserting sheet module (18) is arranged above the slide making module (17), the automatic slide making mechanism (1) comprises a first lifting module (110) arranged above, and the automatic slide making mechanism (1) further comprises a preservation liquid cylinder linked machine slide grid (111) arranged below; the automatic dip-dyeing mechanism (2) with multiple dye vats comprises a plurality of dyeing vats (23) which are sequentially placed, a cleaning vat (24), a baking vat (25) and a manual unloading vat position (26) are sequentially placed on the outer side of each dyeing vat (23), and the automatic dip-dyeing mechanism (2) with multiple dye vats comprises a second lifting module (21) arranged above; many dye vats dip-dye mechanism (2) include transverse guide (28) of top installation, longitudinal rail (29) are installed at transverse guide (28) both ends, the top of module (21) is lifted by crane to the second passes through motor and actuating mechanism and moves on transverse guide (28), transverse guide (28) both ends are passed through motor and actuating mechanism and are removed along longitudinal rail (29).
2. Full-automatic fast slide dyeing machine according to claim 1, characterized in that: the automatic slide preparation mechanism (1) is characterized in that a slide placing opening (112) is formed in the position, close to a slide glass grid drawer (13), of the outer wall of the automatic slide preparation mechanism (1), and a slide rack taking-out opening (27) is formed in the position, close to a manual unloading cylinder position (26), of the outer wall of the automatic dip-dyeing mechanism (2) with multiple dye vats.
3. Full-automatic fast slide dyeing machine according to claim 1, characterized in that: the clamping jaw assembly (16) comprises a transverse electric push rod (161), a longitudinal electric push rod (162) and a lifter (163) which are arranged in sequence, the longitudinal electric push rod (162) is arranged on the output end of the transverse electric push rod (161), the lifter (163) is arranged on the output end of the longitudinal electric push rod (162), the output end of the lifter (163) can be rotated and pressed by a first rotating motor (164), the output end of the first rotating motor (164) is provided with a clamping arm (165), a second rotating motor (166) is installed at one side of the first rotating motor (164), the output end of the second rotating motor (166) is provided with a slide rack clamping rod (167), the clamping arms (165) are two rods which are symmetrically arranged in parallel, grooves are formed in the inner sides of the rods, and L-shaped clamping heads are mounted at two ends of the slide frame clamping rod (167).
4. Full-automatic fast slide dyeing machine according to claim 1, characterized in that: slide module (17) are including fixing base (171), slide station (172) are installed on the inboard upper portion of fixing base (171), the below of slide station (172) is provided with filter bowl membrane section of thick bamboo station (173), the below of fixing base (171) is provided with straw (174), suction groove (1741) is installed at the top of straw (174), filter bowl membrane section of thick bamboo lid constant head tank (175) have been seted up to top one side of fixing base (171), the lift is installed to one side of filter bowl membrane section of thick bamboo station (173), filter bowl membrane section of thick bamboo station (173) can go up and down through the lift.
5. Full-automatic fast slide dyeing machine according to claim 1, characterized in that: the automatic slide making mechanism (1) is provided with a code mutual searching and identifying mechanism of the sample and the slide glass, can automatically identify the sample code, print the code on the slide glass, and also can automatically identify and extract the corresponding sample according to the code on the slide glass.
6. Full-automatic fast slide dyeing machine according to claim 1, characterized in that: the automatic dip dyeing mechanism (2) is also provided with devices such as ultrasound, temperature rise and the like, so that the dyeing processing time is reduced.
7. Full-automatic fast slide dyeing machine according to claim 1, characterized in that: the devices such as samples, film-making consumables and slide racks are designed by adopting a design structure of desktop discharge and drawer storage according to one or more standard fluxes, and one standard flux can be designed in the range of 2-80 samples.
8. Full-automatic fast slide dyeing machine according to claim 1, characterized in that: the automatic slide making mechanism (1) is characterized in that the slide is transferred from the slide glass grid drawer (113) to the slide making station and from the slide making station to the slide rack by adopting a one-dimensional horizontal pushing structure, so that the transfer reliability is ensured.
9. Full-automatic fast slide dyeing machine according to claim 1, characterized in that: a waste bin (19) is arranged below the tabletting module (17).
10. Full-automatic fast slide dyeing machine according to claim 1, characterized in that: the automatic dip-dyeing machine is characterized in that the number of the cleaning cylinder (24) and the number of the baking cylinder (25) are at least two, the two ends of the dyeing cylinder (23) are respectively provided with an automatic loading cylinder position (232), a manual loading cylinder position (231), a manual unloading cylinder position (26) and a cover piece automatic transfer cylinder position (233), and a counting scanner (22) is arranged above the inside of the automatic dip-dyeing mechanism (2) with multiple dyeing cylinders.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110848025.7A CN113533006A (en) | 2021-07-27 | 2021-07-27 | Full-automatic dyeing machine capable of quickly preparing slices |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202110848025.7A CN113533006A (en) | 2021-07-27 | 2021-07-27 | Full-automatic dyeing machine capable of quickly preparing slices |
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| CN202110848025.7A Pending CN113533006A (en) | 2021-07-27 | 2021-07-27 | Full-automatic dyeing machine capable of quickly preparing slices |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114689406A (en) * | 2022-03-31 | 2022-07-01 | 北京华伊智能医疗科技有限公司 | Membrane type liquid-based thin-layer cell slide making device and method |
| CN115524194A (en) * | 2022-09-23 | 2022-12-27 | 湖北星盛电气装备研究院有限公司 | Full-automatic dyeing machine capable of quickly preparing slices |
| CN116793799A (en) * | 2023-07-17 | 2023-09-22 | 北京华伊智能医疗科技有限公司 | Full-automatic cell slice-making, dyeing and slice-sealing integrated device |
-
2021
- 2021-07-27 CN CN202110848025.7A patent/CN113533006A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114689406A (en) * | 2022-03-31 | 2022-07-01 | 北京华伊智能医疗科技有限公司 | Membrane type liquid-based thin-layer cell slide making device and method |
| CN114689406B (en) * | 2022-03-31 | 2023-01-10 | 北京华伊智能医疗科技有限公司 | Membrane type liquid-based thin-layer cell slide making device and method |
| CN115524194A (en) * | 2022-09-23 | 2022-12-27 | 湖北星盛电气装备研究院有限公司 | Full-automatic dyeing machine capable of quickly preparing slices |
| CN116793799A (en) * | 2023-07-17 | 2023-09-22 | 北京华伊智能医疗科技有限公司 | Full-automatic cell slice-making, dyeing and slice-sealing integrated device |
| CN116793799B (en) * | 2023-07-17 | 2024-03-12 | 北京华伊智能医疗科技有限公司 | Full-automatic cell slice-making, dyeing and slice-sealing integrated device |
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