CN211292231U - Safe and rapid automatic processing equipment for biological samples - Google Patents

Safe and rapid automatic processing equipment for biological samples Download PDF

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Publication number
CN211292231U
CN211292231U CN201921571627.7U CN201921571627U CN211292231U CN 211292231 U CN211292231 U CN 211292231U CN 201921571627 U CN201921571627 U CN 201921571627U CN 211292231 U CN211292231 U CN 211292231U
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sample
reagent
frame
wall
cylinder
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肖国林
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Hubei Taikang Medical Equipment Co ltd
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Hubei Taikang Medical Equipment Co ltd
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Abstract

The utility model discloses a safe quick automatic processing equipment of biological sample, which comprises a frame, fixedly connected with work platen in the frame, the work platen becomes treatment chamber, the reagent chamber that sets up about the frame internal partitioning, be equipped with sample processing mechanism, sample waxing mechanism, preheat mechanism, hanging flower basket loading transfer mechanism in the treatment chamber, the reagent intracavity is equipped with reagent distribution transmission device, the frame top is equipped with air treatment device, be equipped with the extraction opening on the frame lateral wall, extraction opening and air treatment device intercommunication, be equipped with the power pack on the frame inner wall, be equipped with the control box on the frame outer wall. The utility model provides high sample processing speed and efficiency and sample throughput, and practice thrift reagent, pollution abatement, the process flow is standardized, can improve sample treatment quality and degree of uniformity, can also reduce operating personnel's the work degree of difficulty and intensity, practices thrift manpower resources.

Description

Safe and rapid automatic processing equipment for biological samples
Technical Field
The utility model relates to a biological sample handles technical field, especially relates to a biological sample safe quick automatic processing equipment.
Background
The collection and pretreatment of biological samples are important links of clinical examination, and the accuracy of subsequent detection results is directly influenced. At present, the collection mode of biological samples is to collect samples (tissue cells and exfoliated cells such as tissues, urine, sputum, hydrothorax and ascites, needle aspiration and the like) into corresponding containers. The inspector opens the container to remove the sample therefrom, or adds and replaces a processing liquid to the container to complete the pretreatment process of the sample. One of the major drawbacks of this procedure is that the toxic components in the reagent volatilize out to pollute the room air when the container is opened by the inspector, and the health of the indoor personnel is damaged.
And current biological sample processing apparatus needs a large amount of manual intervention, and sample processing speed, quality and efficiency are lower, and can't handle the sample of different grade type in same processing cylinder simultaneously, and sample throughput is relatively poor, and the reagent waste is comparatively serious during the processing, and operating personnel's the work degree of difficulty and intensity are higher.
SUMMERY OF THE UTILITY MODEL
The utility model aims at solving the defects existing in the prior art and providing a safe and rapid automatic processing device for biological samples.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
the safe and rapid automatic biological sample processing equipment comprises a rack, wherein a working table plate is fixedly connected in the rack and divides the interior of the rack into a processing cavity and a reagent cavity which are arranged up and down, a sample processing mechanism, a sample waxing mechanism, a preheating mechanism and a hanging basket loading and transferring mechanism are arranged in the processing cavity, a reagent distributing and conveying mechanism is arranged in the reagent cavity, an air processing device is arranged at the top of the rack, an air suction hole is formed in the side wall of the rack and communicated with the air processing device, a power supply box is arranged on the inner wall of the rack, and a control box is arranged on the outer wall of the rack.
Preferably, the sample processing mechanism comprises a sample processing cylinder, a heating and heat-insulating device is arranged on the outer wall of the sample processing cylinder, a plurality of groups of ultrasonic devices are uniformly installed on the outer wall of the sample processing cylinder, the ultrasonic devices are embedded on the heating and heat-insulating device, a plurality of layered liquid level sensors are arranged on the inner wall of the sample processing cylinder along the vertical direction, a waste liquid pipe is connected to the bottom of the sample processing cylinder, the other end of the waste liquid pipe is connected with a waste liquid tank, a liquid discharge valve is arranged on the waste liquid pipe, a magnetic stirring mechanism positioned below the sample processing cylinder is arranged on the working table plate, the magnetic stirring mechanism comprises a stirring motor fixedly installed on the working table plate, a fixing frame is fixedly connected to the working table plate, the fixing frame covers the outer side of the stirring motor, and the tail end of an output shaft, the inner bottom of the sample processing cylinder is provided with a magnetic stirrer matched with the driving magnetic block, the inner bottom wall of the sample processing cylinder is fixedly connected with a protective frame, and the protective frame is covered on the outer side of the magnetic stirrer.
Preferably, sample waxing mechanism is including the waxing jar, be equipped with heating heat preservation device on the outer wall of waxing jar, evenly install multiunit ultrasonic device on the waxing jar outer wall, ultrasonic device inlays to be established on heating heat preservation device, the inner wall of sample treatment jar is provided with a plurality of layering level sensor along vertical direction, the waxing jar lower extreme is connected with the paraffin removal pipe, be equipped with the paraffin removal valve on the paraffin removal pipe.
Preferably, the hanging basket loading and transferring mechanism comprises a sample hanging basket, a hanging basket bin, a hanging basket taking and placing opening and a hanging basket taking and placing mechanism, the hanging basket bin is arranged inside the treatment cavity, the hanging basket taking and placing mechanism comprises a rotating motor fixedly installed at the upper end of the working table plate, the rotating motor is located between the sample treatment cylinder and the wax dipping cylinder, an output shaft of the rotating motor is vertically upwards, the tail end of the output shaft of the rotating motor is fixedly connected with an electric lifting rod, the movable end of the electric lifting rod is vertically inserted into and fixedly connected with a hanging rack, and the sample hanging basket is hung at the lower end of.
Preferably, the hanging basket loading and transferring mechanism comprises a sample hanging basket, a hanging basket bin, a hanging basket taking and placing opening, and a hanging basket taking and placing mechanism, wherein the hanging basket bin is arranged inside the treatment cavity, the hanging basket taking and placing mechanism comprises two horizontal guide rails arranged in the treatment cavity, the two horizontal guide rails are connected with the same translation mechanism, the translation mechanism is provided with a vertical guide rail, the vertical guide rail is provided with a lifting mechanism, the movable end of the lifting mechanism is fixedly connected with a hanging rack, and the sample hanging basket is hung at the lower end of the hanging rack.
Preferably, reagent distribution transport mechanism is including setting up a plurality of hierarchical reagent jars of bottom in the frame, and a plurality of hierarchical reagent jars set gradually along the rank order, every all be connected with the reagent pipeline on the hierarchical reagent jar, every all be equipped with the distributing valve on the reagent pipeline.
Preferably, preheat the mechanism and include the heating jar of fixed mounting in the treatment chamber, be equipped with heating heat preservation device on the outer wall of heating jar, the inner wall of heating jar is provided with a plurality of layering level sensor along vertical direction, be connected with on the heating jar and annotate the liquid pipe, the other end of annotating the liquid pipe is connected on the sample treatment jar, it annotates the liquid valve to be equipped with on the liquid pipe to annotate, be connected with the transfer line on the heating jar, every the reagent pipeline all is connected with the transfer line, be equipped with transfer pump, flow sensor on the transfer line.
Preferably, the bottom of each grading reagent tank is provided with a weight sensor.
Preferably, the air treatment device comprises an exhaust fan, the air inlet end of the exhaust fan is connected with the air exhaust hole through a connecting pipe, the air outlet end of the exhaust fan is connected with a filter box, and a filter element is arranged in the filter box.
Compared with the prior art, the beneficial effects of the utility model are that:
(1) the utility model discloses an ultrasonic wave has been increased in the processing procedure, functions such as heating heat preservation and magnetic stirring, in order to shorten sample processing time, the ultrasonic device outside the sample processing jar wall launches high frequency ultrasonic wave and can pierce through stainless steel jar wall, make the reagent in the jar produce countless small vacuum bubble, form the cavitation effect, when the bubble pressurized blasting, can produce countless number of shock effects in the twinkling of an eye, in addition improve the temperature of reagent and sample and the effect of magnetic stirring can increase the motion speed of molecule, chemical reagent permeates into in every tissue fast under above-mentioned combined action, replace the moisture of tissue, grease and relevant material etc. fast, and do not harm the structure and the cell of tissue; and paraffin can fully and quickly permeate into tissues during paraffin dipping, so that the sample processing speed is increased.
(2) The utility model discloses a set up and preheat the mechanism, preheat the mechanism and can reduce total sample processing time in advance to improve processing speed, when sample processing, preheat the mechanism and draw and heat the reagent of next level automatically simultaneously, can practice thrift the heating time of reagent, reach the purpose that reduces total processing time; in the aspect of temperature control, before the set temperature reaches 80%, the temperature is quickly raised in a full-power heating mode, the temperature is controlled in the rest 20% of intervals in a temperature raising mode of gradually reducing the heating power and the heating frequency, and when the set temperature reaches 100%, the temperature is heated in a pulse constant temperature mode, so that the temperature can be accurately controlled and the heating time can be shortened in a staged temperature control mode.
(3) The utility model discloses effective saving treatment reagent reduces the raw materials consumption. Through the design of the automatic distribution and transmission mechanism and the grading reagent tank, the treatment reagent is subjected to gradient use and management, the reagent can be repeatedly used for many times, and the consumption is reduced.
(4) The utility model discloses effectively reduce air pollution. The air pollution to a laboratory is reduced through the closed structure and the air treatment system, the indoor air is kept clean, the pollution emission is reduced, and the environment-friendly and safe effects are realized, and the health of operators is facilitated.
(5) The utility model discloses full automated design, whole sample processing procedure is according to setting up the automatic completion of procedure, and the processing overall process need not artificial intervention, makes the processing procedure standardized, can improve sample treatment quality and degree of uniformity, can also reduce operating personnel's the work degree of difficulty and intensity, practices thrift manpower resources.
Drawings
Fig. 1 is a schematic front structural view of a cross-distributed single-bin structure of an embodiment of a safe, rapid and automatic biological sample processing apparatus provided by the present invention;
fig. 2 is a schematic top view of a cross-distributed single-chamber structure of a safe and rapid automatic biological sample processing apparatus according to an embodiment of the present invention;
FIG. 3 is a schematic front structural view of a horizontally distributed single-bin structure of a safe and rapid automatic biological sample processing apparatus according to an embodiment of the present invention;
fig. 4 is a schematic top view of a horizontally distributed single-chamber structure of a safe and rapid automatic biological sample processing apparatus according to an embodiment of the present invention;
FIG. 5 is a schematic front view of a horizontally-distributed multi-chamber structure of a safe and rapid automatic biological sample processing apparatus according to an embodiment of the present invention;
fig. 6 is a schematic top view of a horizontally distributed multi-chamber structure of a safe and rapid automatic biological sample processing apparatus according to an embodiment of the present invention;
fig. 7 is a schematic structural view of a magnetic stirring mechanism of a safe and rapid automatic biological sample processing device according to the present invention.
In the figure: 1 air treatment device, 2 heating tank, 3 liquid injection valve, 4 transmission pump, 5 ultrasonic device, 6 sample treatment cylinder, 7 liquid discharge valve, 8 flow sensor, 9 distribution valve, 10 grading reagent tank, 11 electric lifting rod, 12 air suction hole, 13 sample basket, 14 wax dipping cylinder, 15 magnetic stirring mechanism, 16 wax discharge valve, 17 working table plate, 18 reagent pipeline, 19 frame, 20 weight sensor, 21 translation mechanism, 22 vertical guide rail, 23 horizontal guide rail, 24 lifting mechanism, 25 layering liquid level sensor, 26 basket cabin, 27 power supply box, 28 heating and heat preservation device, 29 basket taking and placing port, 30 wax discharge pipe, 31 rotating motor, 32 hanging frame, 33 driving magnet block, 34 fixing frame, 35 stirring motor, 36 magnetic stirrer and 37 protection frame.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.
Example one
Referring to fig. 1, 2, 7, a safe quick automatic processing equipment of biological sample, including frame 19, fixedly connected with work platen 17 in the frame 19, work platen 17 separates into the processing chamber that sets up from top to bottom with frame 19 internal partitioning, the reagent chamber, be equipped with sample processing mechanism in the processing chamber, sample waxing mechanism, preheat the mechanism, the hanging flower basket loads and shifts the mechanism, be equipped with reagent distribution transport mechanism in the reagent chamber, frame 19 top is equipped with air treatment device 1, be equipped with extraction opening 12 on the frame 19 lateral wall, extraction opening 12 and air treatment device 1 intercommunication, be equipped with power pack 27 on the frame 19 inner wall, be equipped with the control box on the frame 19 outer wall, be equipped with control system in the control box.
In the utility model, the sample processing mechanism comprises a sample processing cylinder 6, a heating and heat-preserving device 28 is arranged on the outer wall of the sample processing cylinder 6, a plurality of groups of ultrasonic devices 5 (ultrasonic generators) are evenly arranged on the outer wall of the sample processing cylinder 6, the ultrasonic devices 5 are embedded on the heating and heat-preserving device 28, a plurality of layered liquid level sensors 25 are arranged on the inner wall of the sample processing cylinder 6 along the vertical direction, the bottom of the sample processing cylinder 6 is connected with a waste liquid pipe, the other end of the waste liquid pipe is connected with a waste liquid tank, a liquid discharge valve 7 is arranged on the waste liquid pipe, a magnetic stirring mechanism positioned below the sample processing cylinder 6 is arranged on a working bedplate 17, the heating and heat-preserving device of the sample processing cylinder 6, the ultrasonic devices 5 and the magnetic stirring mechanism alone or the combination of the three and the two, the three are combined, the sample dehydration, fixedly connected with mount 34 on the work platen 17, mount 34 covers and establishes in the agitator motor 35 outside, the end of agitator motor 35 output shaft runs through mount 34 and fixedly connected with drive magnetic path 33, the interior bottom of sample processing jar 6 is equipped with and drives magnetic stirrer 36 of magnetic path 33 complex, the interior diapire fixedly connected with protective frame 37 of sample processing jar 6, protective frame 37 covers and establishes in the outside of magnetic stirrer 36, agitator motor 35 rotates, drive magnetic path 33 and rotate, and then drive magnetic stirrer 36 and rotate.
Specifically, the sample waxing mechanism comprises a waxing cylinder 14, a heating and heat-preserving device 28 is arranged on the outer wall of the waxing cylinder 14, a plurality of groups of ultrasonic devices 5 (ultrasonic generators) are uniformly arranged on the outer wall of the waxing cylinder 14, the ultrasonic devices 5 are embedded on the heating and heat-preserving device 28, a plurality of layered liquid level sensors 25 are arranged on the inner wall of the sample processing cylinder 6 in the vertical direction, a wax discharge pipe 30 is connected to the lower end of the waxing cylinder 14, and a wax discharge valve 16 is arranged on the wax discharge pipe 30.
Specifically, the hanging basket loading and transferring mechanism comprises a sample hanging basket 13, a hanging basket bin 26, a hanging basket taking and placing opening 29 and a hanging basket taking and placing mechanism, the number of the hanging basket bins 26 is one, the sample hanging basket 13 adopts a layered structure, the liquid level of the sample processing cylinder 6 adopts layered control, a control system can simultaneously process different types of samples in the same processing cylinder by controlling the liquid level and the processing time, the processing cylinder is very practical for users with small sample amount but various types, the hanging basket bin 26 is arranged in a processing cavity, the hanging basket taking and placing mechanism comprises a rotating motor 31 fixedly arranged at the upper end of a working table plate 17, the rotating motor 31 is positioned between the sample processing cylinder 6 and a wax dipping cylinder 14, an output shaft of the rotating motor 31 is vertically upwards, the tail end of the rotating motor 31 is fixedly connected with an electric lifting rod 11, the movable end of the electric lifting rod 11 is vertically inserted and fixedly connected with a hanging rack 32, the lifting of the sample hanging basket 13 is realized through the electric lifting rod 11, and the transfer of the sample hanging basket 13 is realized through the rotating motor 31.
Specifically, reagent distribution transport mechanism is including setting up a plurality of hierarchical reagent jars 10 of bottom in frame 19, and a plurality of hierarchical reagent jars 10 set gradually (one-level to 20 levels) along the rank order, all is connected with reagent pipeline 18 on every hierarchical reagent jar 10, all is equipped with distributing valve 9 on every reagent pipeline 18.
Specifically, preheat the mechanism and include heating tank 2 of fixed mounting in the treatment chamber, be equipped with heating heat preservation device 28 on heating tank 2's the outer wall, heating tank 2's inner wall is provided with a plurality of layering level sensor 25 along vertical direction, be connected with on heating tank 2 and annotate the liquid pipe, the other end of annotating the liquid pipe is connected on sample treatment jar 6, it annotates liquid valve 3 to be equipped with on the liquid pipe to annotate, be connected with the transfer line on heating tank 2, every reagent pipeline 18 all is connected with the transfer line, be equipped with transfer pump 4 on the transfer line, flow sensor 8.
Specifically, a weight sensor 20 is provided at the bottom of each graded reagent tank 10.
Specifically, air treatment facilities 1 includes the air exhauster, and the inlet end of air exhauster passes through the connecting pipe to be connected with aspirating hole 12, and the end of giving vent to anger of air exhauster is connected with the filter box, is equipped with the filter core in the filter box, through taking out the volatile air of reagent, purifies the volatile and a small amount of air of pollution of reagent, reduces pollution emission.
Example two
Referring to fig. 3-6, 7, a safe and rapid automatic biological sample processing device comprises a rack 19, a working platen 17 is fixedly connected in the rack 19, the working platen 17 divides the inside of the rack 19 into a processing chamber and a reagent chamber which are arranged up and down, a sample processing mechanism, a sample waxing mechanism, a preheating mechanism and a hanging basket loading and transferring mechanism are arranged in the processing chamber, a reagent distributing and conveying mechanism is arranged in the reagent chamber, an air processing device 1 is arranged at the top of the rack 19, an air suction hole 12 is arranged on the side wall of the rack 19, the air suction hole 12 is communicated with the air processing device 1, a power supply box 27 is arranged on the inner wall of the rack 19, a control box is arranged on the outer wall of.
In the utility model, the sample processing mechanism comprises a sample processing cylinder 6, a heating and heat-preserving device 28 is arranged on the outer wall of the sample processing cylinder 6, a plurality of groups of ultrasonic devices 5 (ultrasonic generators) are evenly arranged on the outer wall of the sample processing cylinder 6, the ultrasonic devices 5 are embedded on the heating and heat-preserving device 28, a plurality of layered liquid level sensors 25 are arranged on the inner wall of the sample processing cylinder 6 along the vertical direction, the bottom of the sample processing cylinder 6 is connected with a waste liquid pipe, the other end of the waste liquid pipe is connected with a waste liquid tank, a liquid discharge valve 7 is arranged on the waste liquid pipe, a magnetic stirring mechanism positioned below the sample processing cylinder 6 is arranged on a working bedplate 17, the heating and heat-preserving device of the sample processing cylinder 6, the ultrasonic devices 5 and the magnetic stirring mechanism alone or the combination of the three and the two, the three are combined, the sample dehydration, fixedly connected with mount 34 on the work platen 17, mount 34 covers and establishes in the agitator motor 35 outside, the end of agitator motor 35 output shaft runs through mount 34 and fixedly connected with drive magnetic path 33, the interior bottom of sample processing jar 6 is equipped with and drives magnetic stirrer 36 of magnetic path 33 complex, the interior diapire fixedly connected with protective frame 37 of sample processing jar 6, protective frame 37 covers and establishes in the outside of magnetic stirrer 36, agitator motor 35 rotates, drive magnetic path 33 and rotate, and then drive magnetic stirrer 36 and rotate.
Specifically, the sample waxing mechanism comprises a waxing cylinder 14, a heating and heat-preserving device 28 is arranged on the outer wall of the waxing cylinder 14, a plurality of groups of ultrasonic devices 5 (ultrasonic generators) are uniformly arranged on the outer wall of the waxing cylinder 14, the ultrasonic devices 5 are embedded on the heating and heat-preserving device 28, a plurality of layered liquid level sensors 25 are arranged on the inner wall of the sample processing cylinder 6 in the vertical direction, a wax discharge pipe 30 is connected to the lower end of the waxing cylinder 14, and a wax discharge valve 16 is arranged on the wax discharge pipe 30.
Specifically, the hanging basket loading and transferring mechanism comprises a sample hanging basket 13, a hanging basket bin 26, a hanging basket taking and placing opening 29 and a hanging basket taking and placing mechanism, the number of the hanging basket bins 26 can be one or more, the sample hanging basket 13 adopts a layered structure, the liquid level of the sample processing cylinder 6 adopts layered control, a control system can simultaneously process different types of samples in the same processing cylinder by controlling the liquid level and the processing time, the method is very practical for users with small sample amount but various types, meanwhile, the multi-bin structure can continuously realize the processing of batch samples, the hanging basket bin 26 is arranged in the processing cavity, the hanging basket taking and placing mechanism comprises two horizontal guide rails 23 arranged in the processing cavity, the two horizontal guide rails 23 are connected with the same translation mechanism 21, the translation mechanism 21 is provided with a vertical guide rail 22, the vertical guide rail 22 is provided with a lifting mechanism, and the movable end of the lifting mechanism is fixedly connected with a hanging rack 32, the sample hanging basket 13 is hung at the lower end of the hanging frame 32.
Specifically, reagent distribution transport mechanism is including setting up a plurality of hierarchical reagent jars 10 of bottom in frame 19, and a plurality of hierarchical reagent jars 10 set gradually (one-level to 20 levels) along the rank order, all is connected with reagent pipeline 18 on every hierarchical reagent jar 10, all is equipped with distributing valve 9 on every reagent pipeline 18.
Specifically, preheat the mechanism and include heating tank 2 of fixed mounting in the treatment chamber, be equipped with heating heat preservation device 28 on heating tank 2's the outer wall, heating tank 2's inner wall is provided with a plurality of layering level sensor 25 along vertical direction, be connected with on heating tank 2 and annotate the liquid pipe, the other end of annotating the liquid pipe is connected on sample treatment jar 6, it annotates liquid valve 3 to be equipped with on the liquid pipe to annotate, be connected with the transfer line on heating tank 2, every reagent pipeline 18 all is connected with the transfer line, be equipped with transfer pump 4 on the transfer line, flow sensor 8.
Specifically, a weight sensor 20 is provided at the bottom of each graded reagent tank 10.
Specifically, air treatment facilities 1 includes the air exhauster, and the inlet end of air exhauster passes through the connecting pipe to be connected with aspirating hole 12, and the end of giving vent to anger of air exhauster is connected with the filter box, is equipped with the filter core in the filter box, through taking out the volatile air of reagent, purifies the volatile and a small amount of air of pollution of reagent, reduces pollution emission.
The utility model discloses during the use, preheat, the sample quantity of handling as required earlier sets up the quantity of reagent, carries the heating jar 2 of preheating the mechanism with one-level reagent in the graded reagent jar 10 according to the quantity that sets up through reagent distribution transmission mechanism again, starts heating heat preservation device 28 on the heating jar 2, heats and keeps warm, starts the heating heat preservation device 28 of sample treatment jar 6 simultaneously.
And in the sample preparation, in the preheating process, samples to be processed are manually loaded into the sample baskets 13 according to the sample classification layers, then the basket bin 26 of the basket loading and transferring mechanism is opened, the sample baskets 13 are loaded into the basket bin 26, and the basket bin 26 is closed.
After sample treatment, after preheating is completed, the sample hanging basket 13 is moved from the hanging basket bin 26 to the sample treatment cylinder 6 through the hanging basket taking and placing opening 29 by the hanging basket loading and transferring mechanism, then the preheated reagent is injected into the sample treatment cylinder 6 through the injection valve 3, the height of the injected reagent is monitored and controlled by the layered liquid level sensor 25 and the control system of the sample treatment cylinder 6 according to the number of layers of the samples loaded in the sample hanging basket 13, simultaneously the ultrasonic device 5 arranged at the outer side of the sample treatment cylinder 6 and the magnetic stirring mechanism arranged at the bottom of the sample treatment cylinder 6 are started to treat and time the samples, when the samples are treated at this time, the redundant reagent in the heating tank 2 of the preheating mechanism returns to the original graded reagent tank 10 through the reagent distribution and transmission mechanism, then the secondary reagent required in the next step is conveyed into the heating tank 2 for preheating, and the ultrasonic device 5 and the magnetic stirring mechanism of the sample treatment cylinder 6 are stopped after the, opening a liquid discharge valve 7, discharging the reagent in the sample processing tank 6 into a waste liquid tank, closing the liquid discharge valve 7, opening a liquid injection valve 3, injecting a secondary reagent which is preheated in the heating tank 2 into the sample processing tank 6, simultaneously starting the ultrasonic device 5 and the magnetic stirring mechanism to perform secondary processing on the sample, returning the redundant reagent in the heating tank 2 of the preheating mechanism to the original grading reagent tank 10 through a reagent distribution and transmission mechanism during the sample processing, conveying a tertiary reagent required in the next step into the heating tank 2 for preheating, and performing circulating operation in sequence, wherein the maximum 20-grade processing can be performed on the sample.
The method comprises the steps that a sample is subjected to wax dipping, after dehydration, degreasing, transparency and the like of the sample are finished, a sample hanging basket 13 moves into a wax dipping cylinder 14 through a hanging basket loading and transferring mechanism, then an ultrasonic device 5 arranged on the outer side of the wax dipping cylinder 14 is started to carry out wax dipping treatment and time counting, the ultrasonic device 5 of the wax dipping cylinder 14 is stopped after system setting time is reached, the hanging basket loading and transferring mechanism lifts the sample hanging basket 13 to filter out redundant paraffin solution, the sample hanging basket 13 is sent back to a hanging basket bin 26 and prompts that the sample treatment steps are all finished, and the hanging basket 26 is opened to take out the sample hanging basket 13, so that subsequent embedding and the like of the sample can be.
The continuous operation, the equipment is in the standby state at this moment, can carry on the processing of the next batch at any time, if increase the sample processing cylinder 6, soak the wax jar 14 and the quantity of the hanging flower basket storehouse 26 appropriately, for example increase to 2-10, can carry on the uninterrupted processing to the sample of the lot automatically, raise the working efficiency more effectively.
Above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the design of the present invention, equivalent replacement or change should be covered within the protection scope of the present invention.

Claims (9)

1. The utility model provides a biological sample safe quick automatic processing equipment, includes frame (19), its characterized in that, fixedly connected with work platen (17) in frame (19), processing chamber, the reagent chamber that sets up about frame (19) internal partitioning is separated into in work platen (17), be equipped with sample processing mechanism, sample waxing mechanism, preheat mechanism, hanging flower basket and load transfer mechanism in the processing chamber, the reagent intracavity is equipped with reagent distribution transmission device, frame (19) top is equipped with air treatment device (1), be equipped with aspirating hole (12) on frame (19) lateral wall, aspirating hole (12) and air treatment device (1) intercommunication, be equipped with power pack (27) on frame (19) inner wall, be equipped with the control box on frame (19) outer wall.
2. The safe, rapid and automatic biological sample processing equipment according to claim 1, wherein the sample processing mechanism comprises a sample processing cylinder (6), a heating and heat-preserving device (28) is arranged on the outer wall of the sample processing cylinder (6), a plurality of groups of ultrasonic devices (5) are uniformly arranged on the outer wall of the sample processing cylinder (6), the ultrasonic devices (5) are embedded on the heating and heat-preserving device (28), a plurality of layered liquid level sensors (25) are arranged on the inner wall of the sample processing cylinder (6) along the vertical direction, a waste liquid pipe is connected to the bottom of the sample processing cylinder (6), a waste liquid tank is connected to the other end of the waste liquid pipe, a liquid discharge valve (7) is arranged on the waste liquid pipe, a magnetic stirring mechanism located below the sample processing cylinder (6) is arranged on the working table plate (17), and the magnetic stirring mechanism comprises a stirring motor (35) fixedly arranged on the working table plate (17), the sample processing device is characterized in that a fixing frame (34) is fixedly connected to the working table plate (17), the fixing frame (34) covers the outer side of a stirring motor (35), the tail end of an output shaft of the stirring motor (35) penetrates through the fixing frame (34) and is fixedly connected with a driving magnetic block (33), a magnetic stirrer (36) matched with the driving magnetic block (33) is arranged at the inner bottom of the sample processing cylinder (6), a protective frame (37) is fixedly connected to the inner bottom wall of the sample processing cylinder (6), and the protective frame (37) covers the outer side of the magnetic stirrer (36).
3. The safe, rapid and automatic biological sample treatment equipment according to claim 2, wherein the sample waxing mechanism comprises a wax dipping cylinder (14), a heating and heat-preserving device (28) is arranged on the outer wall of the wax dipping cylinder (14), a plurality of groups of ultrasonic devices (5) are uniformly installed on the outer wall of the wax dipping cylinder (14), the ultrasonic devices (5) are embedded on the heating and heat-preserving device (28), a plurality of layered liquid level sensors (25) are arranged on the inner wall of the sample treatment cylinder (6) along the vertical direction, a wax discharging pipe (30) is connected to the lower end of the wax dipping cylinder (14), and a wax discharging valve (16) is arranged on the wax discharging pipe (30).
4. The biological sample safe, rapid and automatic processing equipment according to claim 1, wherein the basket loading and transferring mechanism comprises a sample basket (13), a basket bin (26), a basket taking and placing opening (29), and a basket taking and placing mechanism, the basket bin (26) is arranged inside the processing cavity, the basket taking and placing mechanism comprises a rotating motor (31) fixedly installed at the upper end of the working platen (17), the rotating motor (31) is located between the sample processing cylinder (6) and the wax dipping cylinder (14), the output shaft of the rotating motor (31) is vertically upward, the tail end of the output shaft is fixedly connected with an electric lifting rod (11), the movable end of the electric lifting rod (11) is vertically inserted and fixedly connected with a hanging rack (32), and the sample basket (13) is hung at the lower end of the hanging rack (32).
5. The biological sample safe, rapid and automatic processing equipment according to claim 1, wherein the hanging basket loading and transferring mechanism comprises a sample hanging basket (13), a hanging basket bin (26), a hanging basket taking and placing opening (29) and a hanging basket taking and placing mechanism, the hanging basket bin (26) is arranged inside the processing cavity, the hanging basket taking and placing mechanism comprises two horizontal guide rails (23) arranged inside the processing cavity, the two horizontal guide rails (23) are connected with the same translation mechanism (21), the translation mechanism (21) is provided with a vertical guide rail (22), the vertical guide rail (22) is provided with a lifting mechanism, the movable end of the lifting mechanism is fixedly connected with a hanging rack (32), and the sample hanging basket (13) is hung at the lower end of the hanging rack (32).
6. The apparatus for safely, rapidly and automatically processing the biological samples according to claim 2, wherein the reagent distribution and transmission mechanism comprises a plurality of graded reagent tanks (10) arranged at the bottom in the rack (19), the graded reagent tanks (10) are arranged in sequence along a grading sequence, each graded reagent tank (10) is connected with a reagent pipeline (18), and each reagent pipeline (18) is provided with a distribution valve (9).
7. The safe and rapid automatic biological sample treatment equipment according to claim 6, wherein the preheating mechanism comprises a heating tank (2) fixedly installed in the treatment cavity, a heating and heat-preserving device (28) is arranged on the outer wall of the heating tank (2), a plurality of layered liquid level sensors (25) are arranged on the inner wall of the heating tank (2) along the vertical direction, a liquid injection pipe is connected to the heating tank (2), the other end of the liquid injection pipe is connected to the sample treatment tank (6), a liquid injection valve (3) is arranged on the liquid injection pipe, an infusion pipe is connected to the heating tank (2), each reagent pipeline (18) is connected to the infusion pipe, and a transmission pump (4) and a flow sensor (8) are arranged on the infusion pipe.
8. A safe and rapid automatic processing device for biological samples according to claim 6, characterized in that the bottom of each graded reagent tank (10) is provided with a weight sensor (20).
9. The safe and rapid automatic processing equipment for biological samples according to claim 1, characterized in that the air treatment device (1) comprises an exhaust fan, the air inlet end of the exhaust fan is connected with the air suction hole (12) through a connecting pipe, the air outlet end of the exhaust fan is connected with a filter box, and a filter element is arranged in the filter box.
CN201921571627.7U 2019-09-20 2019-09-20 Safe and rapid automatic processing equipment for biological samples Active CN211292231U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110595853A (en) * 2019-09-20 2019-12-20 湖北泰康医疗设备有限公司 Safe and rapid automatic processing equipment for biological samples

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110595853A (en) * 2019-09-20 2019-12-20 湖北泰康医疗设备有限公司 Safe and rapid automatic processing equipment for biological samples
CN110595853B (en) * 2019-09-20 2024-03-29 湖北泰康医疗设备有限公司 Biological sample safe and quick automatic processing equipment

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