CN113509397A - Anti-aging essence containing jasmine flowers and preparation method thereof - Google Patents

Anti-aging essence containing jasmine flowers and preparation method thereof Download PDF

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CN113509397A
CN113509397A CN202010488952.8A CN202010488952A CN113509397A CN 113509397 A CN113509397 A CN 113509397A CN 202010488952 A CN202010488952 A CN 202010488952A CN 113509397 A CN113509397 A CN 113509397A
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aging
essence
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廖云麒
黄春辉
邹佛山
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Guangxi Shilin Molly Biotechnology Group Co ltd
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Guangxi Shilin Molly Biotechnology Group Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/73Polysaccharides
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

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Abstract

The invention discloses an anti-aging essence containing jasmine flowers and a preparation method thereof, wherein the formula comprises the following components in percentage by weight: 85-90% of water; 3-5% of 1.3-propylene glycol; 0.05-0.1% of carbomer; 1-3% of glycerol; 0.2-0.5% of p-hydroxyacetophenone; 0.2-0.5% of 1, 2-glycol; 0.01-0.03% of sodium hyaluronate; 0.01-0.03% of EDTA-2 Na; 0.06-0.1% of PEG-90M; 0.1-0.2% of arginine; 0.01-0.02% of essence; 0.02-0.08% of PEG-60 hydrogenated castor oil; 0.5-2% of jasmine flower extract; 0.5-2% of yeast/rice fermentation product; 0.5-2% of alpinia zerumbet extract. The jasmine flower extract can improve the metabolism of cells, comprehensively slow down the oxidation of the cells and reduce the generation of free radicals, and the yeast/rice fermentation product can promote the generation of collagen, improve the elasticity of skin and improve the problem of rough skin, so that the skin becomes smooth and fine, and the yeast can release metabolites such as polypeptide, amino acid and cell factor in the growth process, thereby effectively nourishing the skin and delaying the aging of the skin.

Description

Anti-aging essence containing jasmine flowers and preparation method thereof
Technical Field
The invention relates to the technical field of preparation of anti-aging essence, and particularly relates to anti-aging essence containing jasmine flowers and a preparation method thereof.
Background
With the increase of age, the combined action of the human physiological environment and the external environment, skin aging is an inevitable trend, but people who love beauty, especially female consumers, constantly seek better and safer anti-aging wrinkle-removing products, and since the end of the 20 th century, more and more researches on skin anti-aging become one of the focuses of people's attention, and the evaluation of safety and efficacy naturally becomes the key focus of the consumers and manufacturers.
The aging is manifested by skin relaxation, wrinkle, vasodilatation, epidermal dyskeratosis, abnormal proliferation, dermal elastic fibrosis, accumulation of degradation products and the like, reasonable nutrition can partially inhibit physiological aging, but the skin is difficult to be protected from the external environment, and the premature aging of the skin can be inhibited only by timely supplementing nutrients.
At present, anti-aging products in China mainly use synthetic raw materials, and certain irritation may exist during use, so that the development of natural anti-aging additives with good safety, stability and obvious effect becomes one of the main research directions of the current cosmetic industry.
Disclosure of Invention
The invention aims to provide an anti-aging essence containing jasmine flowers and a preparation method thereof, and aims to solve the problems in the background art.
In order to achieve the purpose, the invention provides the following technical scheme: an anti-aging essence containing jasmine flowers and a preparation method thereof, wherein the formula comprises the following components: water, 1, 3-propylene glycol, carbomer, glycerol, p-hydroxyacetophenone, 1, 2-hexanediol, sodium hyaluronate, EDTA-2Na, PEG-90M, arginine, essence, PEG-60 hydrogenated castor oil, a jasmine flower extract, a yeast/rice fermentation product and a alpinia japonica extract, wherein the formula proportion is as follows: 89.82 parts of water; 1.3-propylene glycol 4.00; carbomer 0.08; 2.00 parts of glycerol; 0.40 parts of p-hydroxyacetophenone; 0.40 parts of 1, 2-ethanediol; 0.02 parts of sodium hyaluronate; EDTA-2Na 0.02; PEG-90M 0.08; 0.12 of arginine; 0.01 of essence; PEG-60 hydrogenated Castor oil 0.05; 1, jasmine flower extract; yeast/rice fermentation product 1; 1 of alpinia zerumbet.
Preferably, the 1, 3-propylene glycol, the glycerol, the carbomer, the sodium hyaluronate and the EDTA-2Na are respectively added into water to be uniformly dispersed to form item A, and then the item A is added into a reaction kettle to be heated to 80-85 ℃, and then the mixture is uniformly stirred.
Preferably, after uniformly mixing the 1, 2-hexanediol and the p-hydroxyacetophenone, heating to about 80 ℃ to completely dissolve the 1, 2-hexanediol and the p-hydroxyacetophenone to obtain item B, adding the item B into the reaction kettle, uniformly stirring, and cooling.
Preferably, the jasmine extract, the yeast/rice fermentation product and the alpinia zerumbet extract are added after the temperature is reduced to below 45 ℃, and the mixture is uniformly stirred.
Preferably, the essence and the PEG-60 hydrogenated castor oil are slightly heated to be completely dissolved, which is item C, and then added into the reaction kettle to be stirred uniformly.
Preferably, the arginine and part of water are pre-dissolved, added into the system and uniformly stirred, the sensory physical and chemical indexes are detected, and after the detection is qualified, a 200-mesh filter screen is used for filtering and discharging.
Compared with the prior art, the invention has the following beneficial effects:
1. the jasmine extract can improve the metabolism of cells, comprehensively slow down the oxidation of the cells and reduce the generation of free radicals, the yeast/rice fermentation product can promote the generation of collagen, improve the elasticity of the skin and improve the problem of rough skin, so that the skin becomes smooth and fine, the yeast can release metabolites such as polypeptide, amino acid, cell factors and the like in the growth process, the skin can be effectively nourished, meanwhile, the free radical erosion is resisted, the skin aging is delayed, the gorgeous alpinia extract can lead the aging cells to regain vitality, the movement capability of the cells is promoted, the cells are kept in a young state, the vitality of the fibroblasts of the aging skin can be improved, the gene expression related to the secretion and synthesis of the fibroblasts and ECM is promoted, the 'social connection' in the skin is promoted, the healthy state of the skin is kept, and in addition, the gorgeous alpinia extract can promote the synthesis of laminin-5, therefore, the connection state of the true epidermis is improved, the skin is tightened, each component plays respective role, supplements each other and promotes each other, and the anti-aging effect can be better achieved. The three components are compounded according to a certain proportion, and meanwhile, the anti-aging essence containing the jasmine raw material is also unexpectedly found to have a certain function of brightening the skin;
the anti-aging essence containing the jasmine raw material can comprehensively resist skin aging from different approaches, is safe and non-irritant to skin, has no toxic or side effect, is stable in property, safe and reliable, has an anti-aging function, and has a good effect of brightening skin due to the fact that the essence contains a large amount of various organic acids required by cell metabolism, promotes and eliminates toxins, and strengthens a skin microcirculation system.
Drawings
FIG. 1 is a diagram of the formulation of example 1 of the present invention;
FIG. 2 is a schematic diagram showing a formulation of comparative example 1 of the present invention;
FIG. 3 is a diagram showing the formulation of comparative example 2 of the present invention;
FIG. 4 is a diagram showing a formulation of comparative example 3 of the present invention;
FIG. 5 is a diagram showing the formulation of comparative example 4 of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-5, an anti-aging essence containing jasmine flowers and a preparation method thereof, the formula of which comprises: water, 1, 3-propylene glycol, carbomer, glycerol, p-hydroxyacetophenone, 1, 2-hexanediol, sodium hyaluronate, EDTA-2Na, PEG-90M, arginine, essence, PEG-60 hydrogenated castor oil, a jasmine flower extract, a yeast/rice fermentation product and a alpinia japonica extract, wherein the formula proportion is as follows: 89.82 parts of water; 1.3-propylene glycol 4.00; carbomer 0.08; 2.00 parts of glycerol; 0.40 parts of p-hydroxyacetophenone; 0.40 parts of 1, 2-ethanediol; 0.02 parts of sodium hyaluronate; EDTA-2Na 0.02; PEG-90M 0.08; 0.12 of arginine; 0.01 of essence; PEG-60 hydrogenated Castor oil 0.05; 1, jasmine flower extract; yeast/rice fermentation product 1; 1, alpinia zerumbet extract;
respectively adding 1, 3-propylene glycol, glycerol, carbomer, sodium hyaluronate and EDTA-2Na into water to be uniformly dispersed, wherein item A is item A, adding into a reaction kettle, heating to 80-85 ℃, and uniformly stirring;
uniformly mixing 1, 2-hexanediol and p-hydroxyacetophenone, heating to about 80 ℃ to completely dissolve B, adding the B into a reaction kettle, uniformly stirring, and cooling;
cooling to 45 deg.C below, adding flos Jasmini sambac extract, yeast/rice fermentation product, and rhizoma Alpiniae Officinarum extract, and stirring;
slightly heating essence and PEG-60 hydrogenated castor oil until the essence and PEG-60 hydrogenated castor oil are completely dissolved to obtain item C, and adding into a reaction kettle to be uniformly stirred;
pre-dissolving arginine and part of water, adding into the system, stirring, detecting sensory physical and chemical indexes, and filtering with a 200-mesh filter screen to discharge after passing inspection.
Anti-aging Effect test
Test method
The method comprises the steps of selecting 100 volunteers with the age level of 30-50 years by adopting a double-blind test research method, dividing the selected volunteers into 5 groups, dividing each group into 20 persons, wherein the average ages of the volunteers are the same, and the specific use method of the sample comprises the steps of cleaning the face of a subject in the morning and evening, uniformly coating the essence with the size of a monobasic coin on the left face and the right face, coating the essence of the embodiment 1 on the left face, coating the same amount of the essence of the comparative example 1 on the right face, testing the elasticity change of the skin of the subject after using the product every week by using a Finland ElastiMeter elasticity tester after a 28-day use period, and detecting and recording the use effect of all the subjects.
(II) Effect evaluation method
1. The anti-aging and anti-wrinkle effects of the anti-aging essence containing the jasmine raw material are evaluated by using the change rate of the texture degree and elasticity of the skin, and the specific method comprises the following steps:
(1) skin texture degree: measuring the texture condition of the facial skin of the testee by using C-Cube, and detecting and recording the texture of the skin of each tester before the test starts; after the test for one month, the skin texture degree of each subject is detected again and recorded, and the skin texture degree reduction rate is calculated by using the following formula: the grain reduction rate is (pre-test value-post-test value)/pre-test value x 100%, and the larger the grain reduction rate is, the better the anti-aging effect is, and the results in each group are average values below.
(2) Skin elasticity: measuring the change condition of the elasticity value of the facial skin of the testee by using a skin elasticity tester (ElastaMeter) to evaluate the elasticity state of the skin, wherein the higher the value is, the better the surface skin elasticity is, and before the test is started, the elasticity of the skin of each tester is detected and recorded; after one month of the test, the elasticity of the skin of each subject is detected again and recorded, and the increase rate of the skin elasticity is calculated by using the following formula: the elastic increase rate (after-test value-before-test value)/before-test value × 100%, the larger the elastic increase rate, the better the antiaging effect, and the results of each group below were average values.
(III) test results
Skin texture test results:
Figure 213325DEST_PATH_IMAGE001
skin elasticity test results
Figure 196325DEST_PATH_IMAGE002
And (4) test conclusion: after the volunteers continuously use for one month, as can be seen from table 1, the skin care effect is also certain when the comparative example 1, namely the blank control, is used, but the average skin texture reduction rate of the volunteers using the essence of the example 1 is up to more than 30%, the phase difference rate is up to more than 20% compared with the comparative example 1, and the facial skin of the volunteers is much smooth after the volunteers reflect the use, as can be seen from table 2, the skin care effect is also certain when the comparative example 1, namely the blank control, is used, but the average skin elasticity increase rate of the volunteers using the essence of the example 1 is up to more than 35%, and the phase difference rate is up to more than 30% compared with the comparative example 1, so that the jasmine flower extract, the yeast/rice fermentation product and the alpinia speciosa extract have good tightening and anti-aging effects when the essence is added into the essence, and the feedback of the volunteers does not cause allergy, itching and skin aging during the use, The side effects such as reddening indicate good safety.
2. Skin lightening efficacy test
Test method
And 20 volunteers aged 30-50 years old are selected to apply the essence of the embodiment 1 on the face of the volunteer in the morning and evening every day, and after the continuous use for 3 weeks, the skin brightening effect is observed by naked eyes.
(II) test results
The skin of 20 volunteers was brightened, 15 volunteers felt the left face to be 90% brighter than the right face, and the remaining 5 volunteers felt the left face to be 75% brighter than the right face.
And (4) test conclusion: the test results show that the left face coated with the essence of example 1 has a certain brightening effect, and the fact that the jasmine extract, the yeast/rice fermentation product and the alpinia speciosa extract have a good skin brightening effect when added into the essence is fully demonstrated.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. An anti-aging essence containing jasmine flowers and a preparation method thereof are characterized in that: the formula comprises the following components: water, 1, 3-propylene glycol, carbomer, glycerol, p-hydroxyacetophenone, 1, 2-hexanediol, sodium hyaluronate, EDTA-2Na, PEG-90M, arginine, essence, PEG-60 hydrogenated castor oil, a jasmine flower extract, a yeast/rice fermentation product and a alpinia japonica extract, wherein the formula proportion is as follows: 85-90% of water; 3-5% of 1.3-propylene glycol; 0.05-0.1% of carbomer; 1-3% of glycerol; 0.2-0.5% of p-hydroxyacetophenone; 0.2-0.5% of 1, 2-glycol; 0.01-0.03% of sodium hyaluronate; 0.01-0.03% of EDTA-2 Na; 0.06-0.1% of PEG-90M; 0.1-0.2% of arginine; 0.01-0.02% of essence; 0.02-0.08% of PEG-60 hydrogenated castor oil; 0.5-2% of jasmine flower extract; 0.5-2% of yeast/rice fermentation product; 0.5-2% of alpinia zerumbet extract.
2. The anti-aging essence containing jasmine flowers and the preparation method thereof according to claim 1, are characterized in that: adding 1, 3-propylene glycol, glycerin, carbomer, sodium hyaluronate and EDTA-2Na into water respectively to disperse uniformly to obtain item A, adding into a reaction kettle, heating to 80-85 ℃, and stirring uniformly.
3. The anti-aging essence containing jasmine flowers and the preparation method thereof according to claim 1, are characterized in that: after uniformly mixing 1, 2-hexanediol and p-hydroxyacetophenone, heating to about 80 ℃ to completely dissolve item B, adding the item B into a reaction kettle, uniformly stirring, and cooling.
4. The anti-aging essence containing jasmine flowers and the preparation method thereof according to claim 1, are characterized in that: and cooling to below 45 ℃, adding the jasmine flower extract, the yeast/rice fermentation product and the alpinia zerumbet extract, and uniformly stirring.
5. The anti-aging essence containing jasmine flowers and the preparation method thereof according to claim 1, are characterized in that: heating essence and PEG-60 hydrogenated castor oil slightly until the essence and PEG-60 hydrogenated castor oil are completely dissolved to obtain item C, and adding into a reaction kettle to be uniformly stirred.
6. The anti-aging essence containing jasmine flowers and the preparation method thereof according to claim 1, are characterized in that: after the arginine and part of water are pre-dissolved, adding the arginine and part of water into a system, uniformly stirring, detecting sensory physical and chemical indexes, and filtering and discharging the material by a 200-mesh filter screen after the sensory physical and chemical indexes are qualified.
CN202010488952.8A 2020-06-02 2020-06-02 Anti-aging essence containing jasmine flowers and preparation method thereof Pending CN113509397A (en)

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Citations (3)

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Publication number Priority date Publication date Assignee Title
CN106074315A (en) * 2016-08-24 2016-11-09 广东芭薇生物科技股份有限公司 A kind of facial mask liquid with multiple skin-care effect and preparation method thereof
CN107982162A (en) * 2018-01-17 2018-05-04 李福禄 A kind of facial mask essence formula
CN110151649A (en) * 2019-05-29 2019-08-23 爱乐星丽化妆品制造(上海)有限公司 Solidifying profit skin-moisturizing, skin water of one kind and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106074315A (en) * 2016-08-24 2016-11-09 广东芭薇生物科技股份有限公司 A kind of facial mask liquid with multiple skin-care effect and preparation method thereof
CN107982162A (en) * 2018-01-17 2018-05-04 李福禄 A kind of facial mask essence formula
CN110151649A (en) * 2019-05-29 2019-08-23 爱乐星丽化妆品制造(上海)有限公司 Solidifying profit skin-moisturizing, skin water of one kind and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
上海沃雪生物科技有限公司: "沃雪茉莉花焕颜锁水面膜", 《国产非特殊用途化妆品备案信息服务平台》 *
怡悦: "艳山姜叶的生物活性", 《国外医学(中医中药分册)》 *

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Application publication date: 20211019