CN113499402B

CN113499402B - Traditional Chinese medicine composition for treating irritable bowel syndrome and preparation method thereof

Info

Publication number: CN113499402B
Application number: CN202110998456.1A
Authority: CN
Inventors: 赵站周; 赵杰; 侯明月; 赵三辉; 赵科杰; 智娟娟; 李小静
Original assignee: Zhao Zhanzhou
Current assignee: Zhao Zhanzhou
Priority date: 2021-08-27
Filing date: 2021-08-27
Publication date: 2022-04-15
Anticipated expiration: 2041-08-27
Also published as: CN113499402A

Abstract

The invention relates to the technical field of traditional Chinese medicine preparation, and provides a traditional Chinese medicine composition for treating irritable bowel syndrome and a preparation method thereof, wherein the traditional Chinese medicine composition comprises the following components in parts by weight: 10-40 parts of sesame seed meal, 10-20 parts of Chinese yam, 10-20 parts of malt, 10-20 parts of poria cocos, 10-20 parts of lotus rhizome node, 10-20 parts of hericium erinaceus, 6-10 parts of lalang grass rhizome, 6-10 parts of lily, 6-10 parts of tremella, 3-6 parts of American ginseng, 3-6 parts of typha and 3-6 parts of liquorice. The preparation method comprises the following steps: selecting → drying → processing → pulverizing → sieving → making into medicament (powder, pill, granule, etc.). The traditional Chinese medicine composition and the preparation process method thereof are simple, convenient to take, safe and effective, and are particularly suitable for treating irritable bowel syndrome.

Description

Traditional Chinese medicine composition for treating irritable bowel syndrome and preparation method thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicine preparation, and particularly relates to a traditional Chinese medicine composition for treating irritable bowel syndrome and a preparation method thereof.

Background

Ibs is the most common disorder of gastrointestinal dysfunction in clinical use, and is a group of clinical symptoms including abdominal pain, abdominal distension and discomfort, which are characterized by a change in bowel habits, accompanied by abnormal stool characteristics, persistent or intermittent attacks, and lack of morphological and biochemical abnormal changes, which can be explained by organic diseases. IBS can be divided into 4 subtypes based on (diagnostic procedure for the common gastrointestinal symptoms of romaniv) and abnormal excretion of the patient: constipation type IBS (IBS-C), diarrhea type IBS (IBS-D), mixed IBS (IBS-M) and indeterminate IBS (IBS-U). Clinically, IBS (IBS-C) and IBS (IBS-D) are common and IBS (IBS-U) is rare. The patients are mainly young people and middle-aged people, the initial morbidity of the patients is rare after the aged people are aged 20-50 years, the morbidity is not obviously reduced, women are more common than men (about 1: 1.2-2: 1: 2: 1), and the patients tend to be aggregated at home. The etiology of IBS is still unclear and no drug is currently available for the treatment of IBS.

The disease is treated by syndrome differentiation treatment and type classification treatment of the traditional Chinese medicine, and a proper traditional Chinese medicine formula is selected according to the characteristics of the traditional Chinese medicine syndrome and the change of the syndrome, and a method for relaxing bowels and stopping diarrhea is used for treating the disease. At present, the market aims at fewer Chinese patent medicines for treating IBS, and the existing prescription has more medicinal flavors and is not suitable for industrial production. One often chooses based on the symptoms of IBS in the patient: ginseng, poria cocos and rhizoma atractylodis macrocephalae powder, ginseng spleen tonifying pills, middle-jiao and qi tonifying pills, four-god pills, monkshood middle-jiao pills, spleen tonifying and intestine benefiting pills, nine-process rhubarb pills, ginseng double intestine strengthening capsules, root-strengthening and intestine benefiting tablets, daphne giraldii and intestine benefiting granules, pain and diarrhea relieving granules, intestine strengthening and diarrhea relieving pills, three-yellow tablets, hemp seed soft capsules, hemp seed pills, hemp seed intestine moistening pills, intestine clearing and bowel relaxing capsules, aloe capsules, nourishing and intestine moistening oral liquid, desert cistanche bowel relaxing oral liquid, astragalus mongholicus and cistanche bowel relaxing oral liquid and other Chinese patent medicines, which are usually Chinese patent medicines for treating symptoms without treating the root causes and are difficult to obtain ideal effects. IBS not only costs a lot of medical resources, but also affects the quality of life of patients, and is one of the reasons for absenteeism. Therefore, it is very important to search a Chinese medicinal formula which is safe and effective for treating IBS and is convenient to take.

Disclosure of Invention

The invention aims to overcome at least one of the defects of the prior art, and provides a traditional Chinese medicine composition for treating irritable bowel syndrome and a preparation method thereof, which are suitable for IBS and constipation, diarrhea, alternate appearance of constipation and diarrhea, abdominal pain, abdominal distension, abdominal discomfort and the like caused by IBS.

The invention adopts the following technical scheme:

a Chinese medicinal composition for treating irritable bowel syndrome comprises the following components: sesame seed meal, Chinese yam, malt, poria cocos, lotus rhizome nodes, hericium erinaceus, lalang grass rhizome, lily, tremella, American ginseng, cattail and liquorice.

In any of the above possible implementation manners, there is further provided an implementation manner, wherein the traditional Chinese medicine composition comprises the following components in parts by weight: 10-40 parts of sesame seed meal, 10-20 parts of Chinese yam, 10-20 parts of malt, 10-20 parts of poria cocos, 10-20 parts of lotus rhizome node, 10-20 parts of hericium erinaceus, 6-10 parts of lalang grass rhizome, 6-10 parts of lily, 6-10 parts of tremella, 3-6 parts of American ginseng, 3-6 parts of typha and 3-6 parts of liquorice.

Any one of the above possible implementation manners further provides an implementation manner, and the sesame seed meal is obtained after the sesame seeds are fried and the squeezing oil yield is 25% -35%.

In any of the above possible implementation manners, there is further provided an implementation manner, wherein the traditional Chinese medicine composition comprises the following components in parts by weight: 15-30 parts of sesame seed meal, 10-15 parts of Chinese yam, 15-20 parts of malt, 15-20 parts of poria cocos, 10-20 parts of lotus rhizome node, 10-15 parts of hericium erinaceus, 6-8 parts of lalang grass rhizome, 6-10 parts of lily, 6-10 parts of tremella, 3-6 parts of American ginseng, 3-6 parts of typha and 3-6 parts of liquorice.

The invention also provides a preparation method of the traditional Chinese medicine composition for treating irritable bowel syndrome, which comprises the following steps:

s1, stir-frying sesame: putting white sesame into a pot, frying the white sesame with slow fire until the surface of the sesame is yellowish, smelling the inherent fragrance of the sesame or frying the white sesame until the sesame swells and cracks to a degree (the frying temperature is 150-; keeping sesame seed meal, crushing and sieving for later use;

s2, stir-frying Chinese yam: pulverizing furnace soil, parching, adding rhizoma Dioscoreae pieces, parching with strong fire while stirring until the rhizoma Dioscoreae pieces become brown, taking out, sieving to remove furnace soil, and cooling; pulverizing, and sieving;

s3, stir-frying malt: spreading bran in a pot, frying until the bran is smoked, pouring clean malt, frying with slow fire while stirring until the surface of the malt is yellow, taking out, removing the bran, and cooling; pulverizing, and sieving;

s4, stir-frying liquorice: putting the licorice root slices into a pot, frying the licorice root slices to be dark yellow with slow fire, taking out the licorice root slices, and cooling the licorice root slices. Pulverizing, and sieving;

s5, drying the rhizoma imperatae and winnowing the scraps. Putting into a pot, parching with slow fire to slight yellow, taking out, and cooling. Pulverizing and sieving;

s6, drying radix Panacis Quinquefolii decoction pieces, pulverizing, and sieving;

s7, respectively oven drying Poria, Hericium erinaceus, Tremella, nodus Nelumbinis Rhizomatis, and rhizoma Typhae decoction pieces, pulverizing, and sieving;

s8, uniformly mixing the components of the traditional Chinese medicine composition prepared in the steps S1 to S7, and carrying out dosage division and packaging to obtain dry powder of the traditional Chinese medicine composition;

wherein, the steps S1 to S7 have no sequence.

Any one of the above possible implementation manners is further provided, wherein sesame seed meal, Chinese yam, malt, licorice, lalang grass rhizome, poria cocos, hericium erinaceus, tremella, lotus rhizome node and cattail are sieved to 24-50 meshes; the American ginseng is sieved to 80 meshes.

In any of the above possible implementations, there is further provided an implementation, in step S2, every 100 kg of yam pieces are stir-fried with 30 kg of furnace soil; in step S3, every 100 kg of malt is stir-fried with 15 kg of bran.

In any of the foregoing possible implementation manners, there is further provided an implementation manner that in step S8, the obtained dried powder of the traditional Chinese medicine composition is prepared into pills, decoctions, granules or granules.

The source and the efficacy of the medicinal materials used by the traditional Chinese medicine composition are illustrated as follows:

1. sesame: it is dry mature seed of Sesamum indicum L.of the family Lipiaceae (sesame is classified into black and white, black is called black sesame, and white is called white sesame). The sesame property: sweet and neutral. It enters liver, kidney and large intestine meridians. The efficacy is as follows: tonify liver and kidney, nourish essence and blood, moisten intestine and dry. The application comprises the following steps: (1) deficiency of essence and blood, dizziness, dim eyesight, tinnitus, deafness, early white hair and beard, and alopecia after illness; (2) constipation due to intestinal dryness.

2. Malt: the product is processed product of mature fruit of Hordeum vulgare L. of Gramineae by germinating and drying. Medicine property: sweet and neutral. It enters spleen and stomach meridians. The efficacy is as follows: move qi and promote digestion, invigorate spleen and stimulate appetite, and promote lactation to relieve distension. The application comprises the following steps: (1) indigestion, abdominal fullness and distention, spleen deficiency and poor appetite; (2) milk stasis, breast distending pain, breast weaning in women; (3) liver depression, hypochondriac pain, and liver and stomach qi pain.

3. Lotus root node: the product is dry rhizome node of Nehumo nucifera Gaertn. Medicine property: sweet, astringent and neutral. It enters liver, lung and stomach meridians. The efficacy is as follows: astringe to stop bleeding and dissipate blood stasis. The application comprises the following steps: hematemesis, hemoptysis, epistaxis, hematuria, metrorrhagia and metrostaxis.

4. Chinese yam: the product is dried rhizome of Dioscorea Opposita Thunb of Dioscoreaceae. Medicine property: sweet and neutral in nature, they enter spleen, lung and kidney meridians. The efficacy is as follows: replenishing qi and nourishing yin, tonifying spleen, lung and kidney, and arresting seminal emission and leukorrhagia, and is applied as follows: (1) poor appetite due to spleen deficiency, loose stool and excessive leucorrhea; (2) cough and asthma due to lung deficiency; (3) seminal emission, leukorrhagia, frequent urination due to kidney deficiency; (4) consumptive heat thirst.

5. Poria cocos: the product is dried sclerotium of Wolf of Poria cocos (Schw.) Cos (belonging to Polyporaceae). Medicine property: sweet, bland and neutral. It enters heart, lung, spleen and kidney meridians. The efficacy is as follows: induce diuresis and drain dampness, invigorate spleen, calm heart and induce tranquilization. The application comprises the following steps: (1) edema and oliguria; (2) phlegm-fluid retention with dizziness and palpitation; (3) spleen deficiency, poor appetite, loose stool and diarrhea; (4) restlessness, palpitation and insomnia.

6. Lily: the product is dried fleshy scale leaf of Lilium tigrinum Thunb, Lilium brownnii F.E.Brown var. viridulum Baker or Lilium pumilum DC. Medicine property: sweet and slightly cold. It enters heart and lung meridians. The efficacy is as follows: nourish yin and moisten lung, clear heart and induce tranquilization. The application comprises the following steps: (1) cough due to yin deficiency, cough with blood; (2) restlessness due to deficiency with pavor, insomnia, dreaminess, absentmindedness.

7. Cogongrass rhizome: the product is dried rhizome of Imperata cylindra Beauv.var.major (Nees) C.E.Hubb. Medicine property: sweet and cold in nature. It enters lung, stomach and bladder meridians. The efficacy is as follows: cool blood to stop bleeding, clear heat and induce diuresis. The application comprises the following steps: (1) hemoptysis, hematemesis, epistaxis, and hematuria; (2) fever with polydipsia, cough with lung heat, vomiting due to stomach heat; (3) jaundice due to damp-heat, edema, oliguria, stranguria due to heat.

8. And (3) hericium erinaceus: the product is dried fruiting body of Hericium erinaceus (Hericium erinaceus) belonging to family Hydnaceae. Mild in nature and sweet in taste. It enters spleen, stomach and heart meridians. The functions are as follows: move qi and promote digestion, invigorate spleen and stimulate appetite, calm the nerves and benefit intelligence. Can be used for treating dyspepsia, abdominal distention and pain, spleen deficiency, anorexia, insomnia, and dreaminess. Benefiting five internal organs and promoting digestion; it is easy to induce kidney essence.

9. White fungus: the product is fruiting body of Tremella fuciformis Berk of Tremella of Tremellaceae. Medicine property: sweet, bland and mild. It enters lung, stomach and kidney meridians. The functions are as follows: nourish yin and moisten lung, tonify qi and nourish stomach, promote the production of body fluid and moisten dryness. The main treatment is as follows: cough due to asthenia, bloody sputum, thirst due to asthenia heat, asthenia after illness, constipation, hypertension, angiosclerosis, etc.

10. American ginseng: the product is dried root of Panax quinquefolium L. Medicine property: sweet, slightly bitter and cool. It enters heart, lung and kidney meridians. The efficacy is as follows: tonify qi, nourish yin, clear heat and promote fluid production. The application comprises the following steps: (1) syndrome of both qi and yin collapse; (2) deficiency of qi and yin, fever, restlessness, fatigue, cough, asthma, phlegm and blood; (3) qi deficiency consuming body fluids, dry mouth and throat, internal heat consuming thirst.

11. Cattail in Shen nong Ben Cao Jing: sweet and mild in taste. Pathogenic qi in the five zang organs and below the heart, rotten and smelly mouth; hardening teeth; improving eyesight; it is beneficial to hearing. It is suitable for long-term administration, and has effects of reducing weight and resisting aging.

12. Licorice root: the product is dried root and rhizome of Glycyrrhiza uralensis Fisch, Glycyrrhiza inflata Bat, or Glycyrrhiza glabra L. Medicine property: sweet and neutral. It enters heart, lung, spleen and stomach meridians. The efficacy is as follows: invigorating spleen and replenishing qi, clearing away heat and toxic material, eliminating phlegm and relieving cough, relieving spasm and pain, and harmonizing the drugs.

The compatibility principle of the Chinese medicinal composition is described as follows:

according to the main clinical manifestations of IBS, the medical names of IBS belong to the spleen and stomach diseases in traditional Chinese medicine: the categories of constipation, diarrhea and abdominal pain. Weakness of the spleen and the stomach and/or liver dysfunction are important links of IBS pathogenesis, liver depression and spleen deficiency are important pathogenesis of IBS, and spleen-kidney yang deficiency and deficiency-excess inclusion are key factors of disease delay and difficulty. The location of IBS is in the intestine, mainly involving the liver, spleen (stomach), kidney and other organs, and is also related to the lung and heart.

The traditional Chinese medicine composition is prepared by traditional Chinese medicines for balancing yin and yang, strengthening body resistance to eliminate pathogenic factors, calming liver, tonifying kidney, strengthening spleen and protecting intestines according to the traditional Chinese medicine theories of holism, treatment based on syndrome differentiation and treatment and the like and according to the formula principle formulated according to the five-organ reinforcing and reducing theory (namely 'spleen desire is slow', acute food is dry and slow, bitter reducing and sweet tonifying). "plateau" is the therapeutic goal.

The traditional Chinese medicine composition is prepared according to a formula guided by the traditional Chinese medicine theory, follows the basic formula rules of 'standing according to the law, outputting from the law and forming into a medicine' and the like, and is prepared from sesame with unique effect and 'crown of eight cereals' according to the formula principle of 'monarch, minister, assistant and messenger' of the traditional Chinese medicine. The Shennong Bencao Jing calls that sesame has sweet and mild taste, mainly damages middle energizer deficiency and shortness of life (voice category), tonifies five internal organs, benefits strength, develops muscle and marrow and brain. It is suitable for long-term administration, and has effects of reducing weight and resisting aging. A giant win; materials listed in pharmacopoeia of the people's republic of China; in life, sesame is not only food but also medicine; medical elders often tell us: one herb of sesame surpasses one pile of herbs, and attention is paid to the application of sesame in treating spleen and stomach diseases. In the section of TCM: sesame is the essential drug for yin tonification, enters liver, kidney and large intestine channels, and has the effects of nourishing liver and kidney, benefiting essence and blood, and moistening intestine dryness. The sesame contains 45-55% of fatty oil and is used for treating constipation due to intestinal dryness; however, it is not suitable for patients with spleen and stomach weakness, phlegm-damp obstruction, abdominal fullness and loose stool due to its greasy property. Therefore, the application of sesame in the treatment of IBS is greatly limited. Therefore, under the guidance of the traditional Chinese medicine processing method of more frying in the meet and more pounding in the meet, the invention adds the preparation process of reducing toxicity and keeping quality of the processed sesame between the frying and the crushing of the sesame: controlling the squeezing degree and oil yield of sesame to be 25-35% when oil is pressed (25-35 kg sesame oil is taken per 100 kg sesame oil, sealed and preserved); the sesame seed meal is left for reuse and is crushed to be used as the medicine. Thus effectively avoiding the side effect of greasiness of the monarch drug sesame, simultaneously keeping the effective components of sesame dietary fiber, vegetable protein, sesamin, sesame acid, 15 to 30 percent of sesame oil and the like, and leading the sesame seed meal to be easier to crush and process into preparations; after being taken, the sesame can be easily digested and absorbed in intestinal tracts, so that the medicinal effect of the sesame is improved. Has bidirectional regulation effect in treating various IBS such as IBS-C, IBS-D, IBS-M and the like, and has better effect through observation. What is more of long-term value is: the unique sesame toxicity-reducing and storage-maintaining preparation process provided by the invention changes waste into valuable in sesame cakes (leftovers after oil pressing of sesame are treated as animal feed or plant fertilizer) after oil pressing of sesame into oil, becomes a main force of a method for preventing and treating ISB, and plays an important role. It should be noted that, if sesame is used to replace sesame seed meal in the formula of the present invention, the therapeutic effect is greatly reduced.

The Chinese yam, the tuckahoe, the malt, the lotus rhizome node, the lily, the cattail and the like have sweet and mild properties, benefit five internal organs, tonify qi and nourish yin, tonify spleen, lung and kidney, lighten body and prolong life after long-term taking, are listed as 'top-grade' in the Shennong herbal classic, and are set as 'minister' medicines in the Chinese medicinal composition. One monarch and several ministers supplement each other and enhance the efficacy. After the Chinese yam is fried by the furnace soil, the Chinese yam has the effects of warming the middle-jiao and tonifying the spleen; stir-frying the malt with bran to enhance the spleen-invigorating and digestion-promoting effects of the malt; the lalang grass rhizome and the liquorice can moderate excessive property after being slightly fried, and the lalang grass rhizome and the liquorice are crisp in texture, fragrant and sweet, easy to crush and effective. The American ginseng is used as an auxiliary medicine for tonifying five internal organs, calming the mind, promoting the heart and developing the intelligence, and the poria cocos, the hericium erinaceus and the tremella fuciformis are taken for a long time to prolong the life, prolong the cell life, promote the metabolism and regulate the gastrointestinal dysfunction. The liquorice is sweet and neutral in nature, enters heart, lung, spleen and stomach channels, and has the effects of tonifying spleen and qi, harmonizing the drugs and the like.

The invention has the beneficial effects that:

the twelve traditional Chinese medicinal materials such as sesame, Chinese yam and the like in the traditional Chinese medicine composition have bidirectional regulation effect on organisms, have mild medicine property, and have the effects of balancing yin and yang, strengthening body resistance to eliminate pathogenic factors, calming liver, tonifying kidney, invigorating spleen and protecting intestines after being prepared. In the aspect of preventing and treating IBS, the problem that purgative drugs are easy to damage vital qi and spleen and stomach is solved; the defect of 'closing a door and keeping a round key' of astringency medicine is avoided; the long-term administration of the composition can improve the intestinal environment, increase the nutrition of the intestinal tract, repair the intestinal mucosa, rebuild the intestinal function and has obvious effect of preventing and treating IBS.

Detailed Description

Hereinafter, specific embodiments of the present invention will be described in detail. It should be noted that technical features or combinations of technical features described in the following embodiments should not be considered as being isolated, and they may be combined with each other to achieve better technical effects.

The Chinese medicinal composition has the following indications: IBS and constipation, diarrhea, constipation and diarrhea caused by IBS alternately appear, and abdominal pain, abdominal distension, abdominal discomfort and the like.

The embodiment of the invention provides a traditional Chinese medicine composition for treating irritable bowel syndrome, which comprises the following components: sesame seed meal, Chinese yam, malt, poria cocos, lotus rhizome nodes, hericium erinaceus, lalang grass rhizome, lily, tremella, American ginseng, cattail and liquorice.

As a specific embodiment, the traditional Chinese medicine composition comprises the following components in parts by weight: 10-40 parts of sesame seed meal, 10-20 parts of Chinese yam, 10-20 parts of malt, 10-20 parts of poria cocos, 10-20 parts of lotus rhizome node, 10-20 parts of hericium erinaceus, 6-10 parts of lalang grass rhizome, 6-10 parts of lily, 6-10 parts of tremella, 3-6 parts of American ginseng, 3-6 parts of typha and 3-6 parts of liquorice.

As a specific preferred embodiment, the sesame seed meal is obtained by frying sesame seeds and then squeezing out oil with the oil yield of 25% -35%.

The preparation process flow of the traditional Chinese medicine composition comprises the following steps: crushing the traditional Chinese medicine → sieving → mixing → dividing the dosage → checking the quality → packaging to obtain the dry powder of the traditional Chinese medicine composition.

Specifically, the preparation method of the traditional Chinese medicine composition for treating irritable bowel syndrome in the embodiment of the invention comprises the following steps:

s1, stir-frying sesame: putting white sesame into a pot, frying the white sesame with slow fire until the surface of the sesame is yellowish, smelling the inherent fragrance of the sesame or frying the white sesame until the sesame swells and cracks slightly, putting the fried sesame into an oil press to press and extract oil, and controlling the oil extraction rate of the sesame to be 25-35% (25-35 kg sesame oil is extracted per 100 kg sesame oil and is packaged by the sesame oil); keeping sesame seed meal, crushing and sieving for later use;

s5, drying the rhizoma imperatae and winnowing the scraps. Putting into a pot, parching with slow fire to slight yellow, taking out, and cooling. Pulverizing, sieving, and keeping;

wherein, the steps S1 to S7 have no sequence.

Preferably, the sesame seed meal, the Chinese yam, the malt, the liquorice, the lalang grass rhizome, the poria cocos, the hericium erinaceus, the tremella, the lotus rhizome node and the cattail are sieved to be 24-50 meshes; the American ginseng is sieved to 80 meshes.

Preferably, in step S2, every 100 kg of yam pieces are fried with 30 kg of furnace soil; in step S3, every 100 kg of malt is stir-fried with 15 kg of bran.

In step S8, the obtained dried powder of the Chinese medicinal composition is prepared into pills, decoctions, granules or medicinal granules.

The Chinese medicinal composition powder is a main preparation form for clinical application, is recorded according to the ancient records of 'dispersing and removing acute diseases', and has the characteristics of easy dispersion and quick response. The special preparation process of the invention increases the surface area of the medicine powder, has simple preparation, can increase or decrease the dosage according to the disease condition and is convenient to apply. The effective components of the traditional Chinese medicine are better kept, the benign stimulation to the intestinal mucosa is enhanced, and the hygroscopicity and the chemical activity of the traditional Chinese medicine are correspondingly increased.

The traditional Chinese medicine composition powder has the following common dosage:

10-20g for one time, and 2-3 times a day. The dosage can be increased or decreased according to the need of the disease.

The taking method comprises the following steps: 10-20g of the traditional Chinese medicine composition is taken after being mixed with 100-200ml of boiling water or mixed with milk and placed into porridge for micro-boiling before eating.

Note that cold, cool, spicy and pungent foods are not suitable for eating during the treatment period.

Adverse reactions: after the traditional Chinese medicine composition is taken, part of the patient feels satiety, and the continuous treatment is not influenced.

Toxic and side effects: has no toxic and side effects.

Contraindications: those who are allergic to the Chinese medicinal composition of the invention; pregnant and lactating women.

The storage method comprises the following steps: placing in a cool and dry place.

Example 1

The traditional Chinese medicine composition comprises the following components in parts by weight:

30g of sesame seed meal, 15g of Chinese yam, 15g of malt, 15g of poria cocos, 15g of lotus rhizome node, 15g of hericium erinaceus, 6g of lalang grass rhizome, 8g of lily, 8g of tremella, 5g of American ginseng, 5g of typha and 3g of liquorice are taken. Making the Chinese medicinal composition into powder; 10-20g for one time, and 2-3 times a day. Adding 100 and 200ml of boiled water, or adding milk, decocting in porridge, and taking before meal. The formula is suitable for constipation type IBS (IBS-C), diarrhea type IBS (IBS-D), mixed type IBS (IBS-M) and indeterminate type IBS (IBS-U).

Example 2

taking 10g of sesame seed meal, 10g of Chinese yam, 10g of malt, 10g of poria cocos, 10g of lotus rhizome node, 10g of hericium erinaceus, 6g of lalang grass rhizome, 6g of lily, 6g of tremella, 3g of American ginseng, 3g of typha and 3g of liquorice. The above medicines are prepared into pills, and each pill is 9g, 1-2 pills, and 2 times a day. Is taken before meal. The formula is suitable for diarrhea type IBS (IBS-D).

Example 3

40g of sesame seed meal, 20g of Chinese yam, 20g of malt, 20g of poria cocos, 20g of lotus rhizome node, 20g of hericium erinaceus, 10g of lalang grass rhizome, 10g of lily, 10g of tremella, 6g of American ginseng, 6g of typha and 6g of liquorice are taken. The traditional Chinese medicine composition is prepared into powder; 10-20g for one time, and 2-3 times a day. Adding 100 and 200ml of boiled water, or adding milk, decocting in porridge, and taking before meal. The formula is suitable for constipation type IBS (IBS-C).

The research on the curative effect of the traditional Chinese medicine composition comprises the following steps:

in order to research the curative effect of the traditional Chinese medicine composition powder on IBS (IBS-based disease diagnosis) treatment, 80 cases of IBS patients are selected for clinical observation according to the Roman IV common gastrointestinal symptom diagnosis process and the traditional Chinese medicine industry standard issued by the State administration of traditional Chinese medicine, namely the national common State of people's republic of China: wherein, 42 cases are male, 58 cases are female; the patients with the age of 18-60 years, the average age of 38 years, the disease course of 6 months-30 years, the average of 9.6 years, 80 patients all adopt the Chinese medicinal composition powder for treating 6 months, and follow-up visit is carried out after stopping taking the medicine for three months.

The clinical curative effect standard is as follows: and (3) curing: the symptoms are completely disappeared, and no relapse occurs after the medicine is stopped for three months; improvement: the symptoms are obviously improved or disappeared, but the symptoms relapse in the later period of stopping the medicine; the disease is not cured: the symptoms are not improved.

The treatment results are as follows: cure 46 cases (accounting for 57.5 percent), improve 34 cases (accounting for 42.5 percent) and have 100 percent of effective rate.

Typical cases are:

case 1: some one in the paragraph, woman, age 33, teacher, Luoyang. Postpartum abdominal pain, abdominal distension and diarrhea for 7 years. Frequent insomnia and dreamful sleep, tiredness and hypodynamia, no breakfast, love to eat uncooked and cold food, abdominal distension and abdominal pain in the lower left abdomen, 3-6 times/d of defecation, 150g/d of defecation amount, thin paste or soft formed defecation without bloody pus. The diagnosis in Luyang hospital after the routine examination of pelvic cavity ultrasound, colonoscope, feces and the like is as follows: sigmoiditis, irritable bowel syndrome. Levofloxacin, tinidazole and mesalazine are used; biologics, probiotic treatment; after that, the traditional Chinese medicine application of the spleen-tonifying and intestine-benefiting pills, the four-god pills, the monkshood middle-regulating pills and the traditional Chinese medicine decoction are repeatedly used for treating more than three years, and the curative effect is poor. Visit to my hospital from 11 months 2012: irritable bowel syndrome (IBS-D), use this Chinese medicinal composition to treat, 15g each time, take twice a day, we propose patient to treat IBS, should keep the mood pleasurable at ordinary times, rational diet, must not eat uncooked cold and cool food, recuperate and treat 6 months by this patent method, fully recover. No relapse is found in three follow-up years.

Case 2: sunzhi, female, 51 years old, salesman, Xiangyang people. The patient feels long working time and high pressure at ordinary times, defecating is difficult for 30 years due to poor defecating habit, the patient often feels abdominal pain and abdominal distension, defecates 1 time every 7-10 days, the feces are dried and formed into sheep manure, mucus sometimes adheres to the feces, the defecation feeling is obvious, and the patient often suffers from insomnia, dreaminess, dysphoria, pessimism and boredom and the like by using cathartic medicines such as phenolphthalein tablets, aloe capsules, senna leaves and the like for a long time to defecate. In 2014, the abdomen pain aggravated to the hospitalization of Wuhan hospital, and the diagnosis was: incomplete intestinal obstruction, irritable bowel syndrome and large intestine melanosis. The long-term treatment in Nanjing, Shanghai and the like has poor curative effect. According to irritable bowel syndrome (IBS-C) in 2017 from 1 month to our hospital, the method is used for recuperating and treating symptoms such as mental condition, appetite, abdominal pain and abdominal distension for 7 months, the condition is obviously improved, and the patient can naturally defecate once a day without laxatives; the treatment is continued for 6 months, the disease is cured, and no relapse is seen after multiple follow-up visits.

Case 3: wangzhi, male, 48 years old, official, Luoyang. The life is irregular, and the patient suffers from abdominal pain, abdominal distension and abnormal defecation for 17 years. Patients are administered in a mixed way for a long time, diarrhea is treated 2-3 times per day by taking medicines such as norfloxacin capsules, cefradine capsules, montmorillonite powder and the like; sometimes, the patient does not defecate for 3 to 5 days, and has abdominal distension, abdominal pain and abdominal discomfort, and the patient uses cold and cool cathartics, often dizziness, tiredness, weakness, depression and the like, seriously influences life and work, and often asks for medical help. No obvious abnormality is found in gastroscopy, colonoscope, abdominal and pelvic ultrasonic wave, etc. The physical examination has no obvious positive sign, and the diagnosis is as follows: irritable bowel syndrome. The long-term treatment is carried out in a certain Luoyang hospital, and the defecation condition is good and bad. By introducing to patients, the traditional Chinese medicine composition powder is naturally and smoothly defecated for 1 time after being applied to the hospital for 18 hours, and after being continuously nursed and treated for 6 months, the abdominal symptoms are obviously relieved, the defecating is basically normal, and the life quality is greatly improved. Then, according to the illness state of the patient, a multi-dimensional comprehensive treatment method is adopted, the patient is ordered to keep living and living regularity for a long time and form good dietary habits, and the abuse of cathartics and antidiarrheal medicines is avoided, so that the curative effect is strengthened. After 4 years of follow-up, IBS occasionally occurs, and the method is used for short-term nursing, so that the life and the work are normal for many years.

In conclusion, IBS is the most common intestinal dysfunction disease in clinic, the pathogenesis is complex, and no effective treatment medicine exists at present. The traditional Chinese medicine composition has good treatment effect, but attention is paid to health management, psychological dispersion and emphasis on improving bad life, dietary habits and the like of patients in the treatment process. Adopts a comprehensive method of multiple dimensions, does not abuse cathartics and antidiarrheal drugs to cause bowel dysfunction, and improves the special efficacy of the traditional Chinese medicine composition in preventing and treating IBS.

The traditional Chinese medicine composition and the preparation process method thereof are simple, convenient to take, safe and effective, and are particularly suitable for treating irritable bowel syndrome.

While several embodiments of the present invention have been presented herein, it will be appreciated by those skilled in the art that changes may be made to the embodiments herein without departing from the spirit of the invention. The above examples are merely illustrative and should not be taken as limiting the scope of the invention.

Claims

1. The traditional Chinese medicine composition for treating irritable bowel syndrome is characterized by comprising the following components in parts by weight: 10-40 parts of sesame seed meal, 10-20 parts of Chinese yam, 10-20 parts of malt, 10-20 parts of poria cocos, 10-20 parts of lotus rhizome node, 10-20 parts of hericium erinaceus, 6-10 parts of lalang grass rhizome, 6-10 parts of lily, 6-10 parts of tremella, 3-6 parts of American ginseng, 3-6 parts of typha and 3-6 parts of liquorice;

the sesame seed meal is obtained by frying sesame seeds and then squeezing out oil with the oil yield of 25% -35%.

2. The traditional Chinese medicine composition for treating irritable bowel syndrome according to claim 1, wherein the traditional Chinese medicine composition comprises the following components in parts by weight: 15-30 parts of sesame seed meal, 10-15 parts of Chinese yam, 15-20 parts of malt, 15-20 parts of poria cocos, 10-20 parts of lotus rhizome node, 10-15 parts of hericium erinaceus, 6-8 parts of lalang grass rhizome, 6-10 parts of lily, 6-10 parts of tremella, 3-6 parts of American ginseng, 3-6 parts of typha and 3-6 parts of liquorice.