CN113499302A - Antibacterial and anti-inflammatory facial cleanser and preparation method thereof - Google Patents
Antibacterial and anti-inflammatory facial cleanser and preparation method thereof Download PDFInfo
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- CN113499302A CN113499302A CN202110676280.8A CN202110676280A CN113499302A CN 113499302 A CN113499302 A CN 113499302A CN 202110676280 A CN202110676280 A CN 202110676280A CN 113499302 A CN113499302 A CN 113499302A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
Abstract
The invention relates to the technical field of cosmetics, and particularly relates to an antibacterial and anti-inflammatory facial cleanser and a preparation method thereof. The raw materials comprise the following components in percentage by weight: phase A: 10-40% of natural plant components, 1-20% of foaming agent, 0.1-5% of stearate, 1-5% of fatty chain amino acid derivative and 0.1-2% of film-forming agent; phase B: 0.01 to 6 percent of sodium salt; and C phase: 4-17% of polyhydric alcohol and derivatives thereof, 0.1-1% of preservative, 0.1-1% of organic acid and the balance of water. The antibacterial and anti-inflammatory facial cleanser provided by the invention has the following advantages: (1) the skin cleaning cream is rich in natural plant components, is mild and non-irritant to skin, can efficiently clean the skin, effectively removes dirt on the surface of the skin, and has strong antibacterial and anti-inflammatory capabilities; (2) the sense experience is good, the skin is moist and elastic and not tight after use, and the skin-friendly performance is strong; (3) the high-temperature-resistant and high-stability high-temperature-resistant paint has the advantages of wide temperature resistance, strong storage stability, capability of being stored for a long time at the temperature of-4-50 ℃, difficulty in color change and layering (4), easiness in obtaining raw materials, simplicity and convenience in process, capability of meeting related industrial requirements of products and wide application prospect.
Description
Technical Field
The invention relates to the technical field of cosmetics, and particularly relates to an antibacterial and anti-inflammatory facial cleanser and a preparation method thereof.
Background
The facial cleanser is a facial cleaning cosmetic, has the main function of removing dirt on the surface layer of facial skin and keeping the skin in a clean and comfortable state, and is the first step of a facial care step. During the use process, the main objects of the facial cleanser are impurities generated by skin, such as sweat, sebum and skin peeling cell fragments secreted by the facial skin of a human body, and dirt outside the skin, such as dust, microorganisms and cosmetic residues adhered to the surface of the skin. The types of the existing facial cleanser mainly comprise solid, cream, liquid, particle, foam and the like, the facial cleanser needs to be mild and non-irritant to the skin while keeping the cleaning effect, and the traditional facial cleanser easily causes the problems of tight and dry skin and excessive cleaning such as skin lipid film damage to sensitive skin.
Chinese patent CN201510316179.6 discloses a facial cleanser containing plant saponin, which adopts ethanol solution to carry out ultrasonic extraction on wild tea oil, camellia seeds, achyranthes aspera, yam, chamomile, glycyrrhiza glabra, radix asparagi, 1-3 parts of safflower, balsam pear, green tea and watermelon seeds, and combines the extracted materials with beeswax, sodium lactate and sodium chloride to obtain the effects of cleaning face and protecting skin. Based on the above, the problem to be solved in the field is to prepare the facial cleanser which is efficient in cleaning face, safe, mild, free of stimulation, antibacterial and anti-inflammatory.
Disclosure of Invention
The invention provides the antibacterial and anti-inflammatory facial cleanser, solves the problems that the facial cleanser in the prior art is poor in cleaning effect and skin is easy to dry, astringent and tight after use, and realizes the efficient facial cleanser which is safe, mild, non-irritant, antibacterial and anti-inflammatory.
The invention provides an antibacterial and anti-inflammatory facial cleanser, which comprises the following raw materials in percentage by weight:
phase A: 10-40% of natural plant components, 1-20% of foaming agent, 0.1-5% of stearate, 1-5% of fatty chain amino acid derivative and 0.1-2% of film-forming agent;
phase B: 0.01 to 6 percent of sodium salt;
and C phase: 4-17% of polyhydric alcohol and derivatives thereof, 0.1-1% of preservative, 0.1-1% of organic acid and the balance of water.
Wherein the raw material weight sum of the phase A, the phase B and the phase C is 100 percent.
In a preferred embodiment, the natural plant component has a glycoside content of > 10% by mass.
In a preferred embodiment, the natural plant components include at least one of soapberry peel extract, sasanqua fruit extract, Chinese honeylocust fruit extract, ginseng extract, licorice extract, bupleurum extract, platycodon root extract, alisma orientale extract, ganoderma lucidum extract, tea extract, and sea cucumber extract.
In a preferred embodiment, the foaming agent comprises at least one of sulfonate compounds, fatty alcohol-polyoxyethylene ether, alkyl glycoside and amino acid derivatives.
In a preferred embodiment, the stearate comprises at least one of polyglyceryl-diisostearate, sorbitan tristearate, glyceryl stearate, polyethylene glycol distearate, PEG-100 stearate, polyoxyethylene stearate, isopropyl stearate, pentaerythritol tetraisostearate, polyoxyethylene sorbitol stearate, cetearyl stearate.
In a preferred embodiment, the fatty chain amino acid derivative comprises at least one of lauroyl glutamate, cocoyl glycinate, cocoyl alanate, stearoyl glutamate, palmitoyl glutamate, cocoyl arginine ester, cocoyl potassium glycinate, lauroyl sarcosinate, cocoyl arginine salt, palmitoyl sarcosinate.
In a preferred embodiment, the sodium salt has a solubility in water of 10 to 40g/100ml and a test temperature of 22 ℃.
In a preferred embodiment, the polyol and derivatives thereof have the structureWherein R is hydrogen or a saturated branched alkyl group.
In a preferred embodiment, the organic acid comprises at least one of phosphoric acid, citric acid, tartaric acid, maleic acid, malic acid.
The invention provides a preparation method of an antibacterial and anti-inflammatory facial cleanser, which comprises the following steps:
s1, weighing phase A raw materials according to the formula amount, uniformly mixing, heating to 70-85 ℃, and uniformly stirring at constant temperature to obtain a mixture I;
s2, weighing the phase B raw materials according to the formula amount, and uniformly mixing to obtain a mixture II;
s3, weighing the C-phase raw materials according to the formula amount, and uniformly mixing to obtain a mixture III;
s4, cooling the first mixture to 35-48 ℃, adding the second mixture and the third mixture into the first mixture, uniformly stirring, and cooling to obtain a finished product.
Has the advantages that:
the antibacterial and anti-inflammatory facial cleanser provided by the invention has the following advantages:
(1) the skin cleaning cream is rich in natural plant components, is mild and non-irritant to skin, can efficiently clean the skin, effectively removes dirt on the surface of the skin, and has strong antibacterial and anti-inflammatory capabilities;
(2) the sense experience is good, the skin is moist and elastic and not tight after use, and the skin-friendly performance is strong;
(3) the temperature resistance is wide, the storage stability is strong, the long-term storage can be realized under the condition of-4 to 50 ℃, and the color change and layering are not easy to occur;
(4) the invention has the advantages of easily obtained raw materials and simple and convenient process, and the product meets the requirements of related industries and has wide application prospect.
Detailed Description
The disclosure may be understood more readily by reference to the following detailed description of preferred embodiments of the invention and the examples included therein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In case of conflict, the present specification, including definitions, will control.
The term "prepared from …" as used herein is synonymous with "comprising". The terms "comprises," "comprising," "includes," "including," "has," "having," "contains," "containing," or any other variation thereof, as used herein, are intended to cover a non-exclusive inclusion. For example, a composition, process, method, article, or apparatus that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, process, method, article, or apparatus.
The conjunction "consisting of …" excludes any unspecified elements, steps or components. If used in a claim, the phrase is intended to claim as closed, meaning that it does not contain materials other than those described, except for the conventional impurities associated therewith. When the phrase "consisting of …" appears in a clause of the subject matter of the claims rather than immediately after the subject matter, it defines only the elements described in the clause; other elements are not excluded from the claims as a whole.
When an amount, concentration, or other value or parameter is expressed as a range, preferred range, or as a range of upper preferable values and lower preferable values, this is to be understood as specifically disclosing all ranges formed from any pair of any upper range limit or preferred value and any lower range limit or preferred value, regardless of whether ranges are separately disclosed. For example, when a range of "1 to 5" is disclosed, the described range should be interpreted to include the ranges "1 to 4", "1 to 3", "1 to 2 and 4 to 5", "1 to 3 and 5", and the like. When a range of values is described herein, unless otherwise stated, the range is intended to include the endpoints thereof and all integers and fractions within the range.
The singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. "optional" or "any" means that the subsequently described event or events may or may not occur, and that the description includes instances where the event occurs and instances where it does not.
Approximating language, as used herein throughout the specification and claims, is intended to modify a quantity, such that the invention is not limited to the specific quantity, but includes portions that are literally received for modification without substantial change in the basic function to which the invention is related. Accordingly, the use of "about" to modify a numerical value means that the invention is not limited to the precise value. In some instances, the approximating language may correspond to the precision of an instrument for measuring the value. In the present description and claims, range limitations may be combined and/or interchanged, including all sub-ranges contained therein if not otherwise stated.
In addition, the indefinite articles "a" and "an" preceding an element or component of the invention are not intended to limit the number requirement (i.e., the number of occurrences) of the element or component. Thus, "a" or "an" should be read to include one or at least one, and the singular form of an element or component also includes the plural unless the stated number clearly indicates that the singular form is intended.
"Polymer" means a polymeric compound prepared by polymerizing monomers of the same or different types. The generic term "polymer" embraces the terms "homopolymer", "copolymer", "terpolymer" and "interpolymer". "interpolymer" means a polymer prepared by polymerizing at least two different monomers. The generic term "interpolymer" includes the term "copolymer" (which is generally used to refer to polymers prepared from two different monomers) and the term "terpolymer" (which is generally used to refer to polymers prepared from three different monomers). It also includes polymers made by polymerizing more monomers. "blend" means a polymer formed by two or more polymers being mixed together by physical or chemical means.
In order to solve the above problems, the invention provides an antibacterial and anti-inflammatory facial cleanser in a first aspect, which comprises the following raw materials in percentage by weight:
phase A: 10-40% of natural plant components, 1-20% of foaming agent, 0.1-5% of stearate, 1-5% of fatty chain amino acid derivative and 0.1-2% of film-forming agent;
phase B: 0.01 to 6 percent of sodium salt;
and C phase: 4-17% of polyhydric alcohol and derivatives thereof, 0.1-1% of preservative, 0.1-1% of organic acid and the balance of water.
Wherein the raw material weight sum of the phase A, the phase B and the phase C is 100 percent.
In some preferred embodiments, the natural plant component has a glycoside content > 10% by mass.
Further preferably, the glycoside is saponin.
The natural plant components with the saponin content of more than 10 percent by mass can be commercially available, such as Guangdong cyanine extract Biotech limited.
In some preferred embodiments, the natural plant components include at least one of soapberry peel extract, sasanqua cake extract, Chinese honeylocust fruit extract, ginseng extract, licorice extract, bupleurum extract, platycodon root extract, alisma orientale extract, ganoderma lucidum extract, tea extract, and sea cucumber extract.
In some preferred embodiments, the natural plant components include at least one of soapberry peel extract, sasanqua cake extract, and saponin extract.
Further preferably, the natural plant component is a soapberry pericarp extract.
In some preferred embodiments, the foaming agent comprises at least one of sulfonate compounds, fatty alcohol-polyoxyethylene ethers, alkyl glycosides, and amino acid derivatives.
Further preferably, the foaming agent is a sulfonate compound.
In some preferred embodiments, the sulfonate-based compounds include disodium lauryl sulfosuccinate and sodium cocoyl methyl taurate.
Further preferably, the weight ratio of the disodium lauryl sulfosuccinate to the sodium cocoyl methyl taurate is (1-3): 1.
in some preferred embodiments, the stearate comprises at least one of polyglyceryl-diisostearate, sorbitan tristearate, glyceryl stearate, polyethylene glycol distearate, PEG-100 stearate, polyoxyethylene stearate, isopropyl stearate, pentaerythritol tetraisostearate, polyoxyethylene sorbitol stearate, cetearyl stearate.
In some preferred embodiments, the stearate includes glyceryl stearate and PEG-100 stearate.
More preferably, the weight ratio of the glycerol stearate to the PEG-100 stearate is (0.5-2): 1.
in some preferred embodiments, the fatty chain amino acid derivative comprises at least one of lauroyl glutamate, cocoyl glycinate, cocoyl alanate, stearoyl glutamate, palmitoyl glutamate, cocoyl arginine ester, cocoyl potassium glycinate, lauroyl sarcosinate, cocoyl arginine salt, palmitoyl sarcosinate.
In some preferred embodiments, the fatty chain amino acid derivative is potassium cocoyl glycinate.
In some preferred embodiments, the sodium salt has a solubility in water of 10 to 40g/100ml and a test temperature of 22 ℃.
In some preferred embodiments, the sodium salt is an organic sodium salt and/or an inorganic sodium salt.
Further preferably, the sodium salt is an organic sodium salt or an inorganic sodium salt.
Still more preferably, the organic sodium salt is EDTA-2Na, the solubility of EDTA-2Na in water is 11g/100ml, and the testing temperature is 22 ℃; the inorganic sodium salt is NaCl, the solubility of NaCl in water is 36g/100ml, and the test temperature is 22 ℃.
In some preferred embodiments, the polyol and derivatives thereof have the structureWherein R is hydrogen or a saturated branched alkyl group.
In some preferred embodiments, the saturated branched alkyl group is ethylhexyl.
In some preferred embodiments, the organic acid comprises at least one of phosphoric acid, citric acid, tartaric acid, maleic acid, malic acid.
According to the invention, the natural plant extract is added into the facial cleanser, and the facial cleanser and the foaming agent, stearate and other substances act together, so that the effect of effectively cleaning the facial skin is achieved. Further, the facial cleanser can effectively remove facial oil stains when the mass content of glycoside in the natural plant extract is more than 10%, and has obvious antibacterial and anti-inflammatory effects. The cleansing cream disclosed by the invention is prepared by compounding glyceryl stearate and PEG-100 stearate, and is adhered to the surface layer of the skin together with substances such as a film-forming agent to form a water-locking protective layer, and water-replenishing substances in the components of the cleansing cream rapidly permeate to the surface layer of the skin under the protective layer, so that the skin absorbs water and small-molecule active substances after being cleaned, and the skin is maintained. The addition of the plant extracts and other substances easily causes the increase of the chaos degree of a composite system and easy layering and color changing, the polyhydric alcohol and the derivatives thereof are added into the formula of the facial cleanser, the compatibility of a water phase and an oil phase in the facial cleanser is effectively improved, the prepared facial cleanser does not have the phenomenon of layering and color changing after being placed at high temperature and low temperature for a long time, the skin is smooth and moist while the skin is efficiently cleaned, and the facial cleanser has excellent storage stability.
The invention provides a preparation method of an antibacterial and anti-inflammatory facial cleanser, which comprises the following specific preparation steps:
s1, weighing phase A raw materials according to the formula amount, uniformly mixing, heating to 70-85 ℃, and uniformly stirring at constant temperature to obtain a mixture I;
s2, weighing the phase B raw materials according to the formula amount, and uniformly mixing to obtain a mixture II;
s3, weighing the C-phase raw materials according to the formula amount, and uniformly mixing to obtain a mixture III;
s4, cooling the first mixture to 35-48 ℃, adding the second mixture and the third mixture into the first mixture, uniformly stirring, and cooling to obtain a finished product.
Examples
In order to better understand the above technical solutions, the following detailed descriptions will be provided with reference to specific embodiments. It should be noted that the following examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention, and that the insubstantial modifications and adaptations of the present invention by those skilled in the art based on the above disclosure are still within the scope of the present invention. In addition, the raw materials are commercially available and the extraction methods of the extract are all conventional extraction methods, if not otherwise specified.
Example 1.
The embodiment provides an antibacterial and anti-inflammatory facial cleanser, which comprises the following raw materials in percentage by weight:
phase A: 25% of natural plant components, 10% of foaming agent, 3% of stearate, 3% of fatty chain amino acid derivative and 0.5% of film forming agent;
phase B: 2.5 percent of sodium salt;
and C phase: 10% of polyhydric alcohol and derivatives thereof, 0.5% of preservative, 0.5% of organic acid and the balance of water.
Wherein the raw material weight sum of the phase A, the phase B and the phase C is 100 percent.
The natural plant components are soapberry peel extracts, the saponin content of the soapberry peel extracts is 15% by mass, and the soapberry peel extracts are purchased from Guangdong cyanine extraction Biotech limited company.
The foaming agent is a sulfonate compound, and the sulfonate compound is disodium lauryl sulfosuccinate and sodium cocoyl methyl taurate. The CAS number of the disodium lauryl sulfosuccinate is 19040-44-9, and the CAS number of the sodium cocoyl methyl taurate is 12765-39-8.
The weight ratio of the disodium lauryl sulfosuccinate to the sodium cocoyl methyl taurate is 2: 1.
the stearate is glyceryl stearate and PEG-100 stearate.
The weight ratio of the glycerol stearate to the PEG-100 stearate is 1: 1. glycerol stearate has CAS number 85666-92-8, PEG-100 stearate has CAS number 9004-99-3.
The fatty chain amino acid derivative is potassium cocoyl glycinate, and the CAS number is 301341-58-2.
The film-forming agent is acrylic acid (ester) copolymer, and is purchased from Wuhan Huazhike scientific biotechnology, Inc.
The sodium salt is organic sodium salt and inorganic sodium salt; the weight ratio of the organic sodium salt to the inorganic sodium salt is 1: 24.
the organic sodium salt is EDTA-2Na, the solubility of the EDTA-2Na in water is 11g/100ml, and the testing temperature is 22 ℃; the inorganic sodium salt is NaCl, the solubility of NaCl in water is 36g/100ml, and the test temperature is 22 ℃.
The polyhydric alcohol and the derivatives thereof are glycerol and ethylhexyl glycerol, and the weight ratio of the glycerol to the ethylhexyl glycerol is 98: 2.
the preservative is phenoxyethanol, and the CAS number is 122-99-6.
The organic acid is citric acid, and the CAS number is 77-92-9.
The second aspect of the embodiment provides a preparation method of an antibacterial and anti-inflammatory facial cleanser, which comprises the following specific preparation steps:
s1, weighing phase A raw materials according to the formula amount, uniformly mixing, heating to 80 ℃, and uniformly stirring at constant temperature to obtain a mixture I;
s2, weighing the phase B raw materials according to the formula amount, and uniformly mixing to obtain a mixture II;
s3, weighing the C-phase raw materials according to the formula amount, and uniformly mixing to obtain a mixture III;
and S4, cooling the mixture I to 45 ℃, adding the mixture II and the mixture III into the mixture I, uniformly stirring, and cooling to obtain a finished product.
Example 2.
The embodiment provides an antibacterial and anti-inflammatory facial cleanser, which comprises the following raw materials in percentage by weight:
phase A: 35% of natural plant components, 15% of foaming agents, 4% of stearate, 5% of fatty chain amino acid derivatives and 1% of film forming agents;
phase B: 4% of sodium salt;
and C phase: 13% of polyhydric alcohol and derivatives thereof, 0.5% of preservative, 1% of organic acid and the balance of water.
Wherein the raw material weight sum of the phase A, the phase B and the phase C is 100 percent.
The natural plant components are soapberry peel extracts, the saponin content of the soapberry peel extracts is 15% by mass, and the soapberry peel extracts are purchased from Guangdong cyanine extraction Biotech limited company.
The foaming agent is a sulfonate compound, and the sulfonate compound is disodium lauryl sulfosuccinate and sodium cocoyl methyl taurate. The CAS number of the disodium lauryl sulfosuccinate is 19040-44-9, and the CAS number of the sodium cocoyl methyl taurate is 12765-39-8.
The weight ratio of the disodium lauryl sulfosuccinate to the sodium cocoyl methyl taurate is 2: 1.
the stearate is glyceryl stearate and PEG-100 stearate.
The weight ratio of the glycerol stearate to the PEG-100 stearate is 1: 1. glycerol stearate has CAS number 85666-92-8, PEG-100 stearate has CAS number 9004-99-3.
The fatty chain amino acid derivative is potassium cocoyl glycinate, and the CAS number is 301341-58-2.
The film-forming agent is acrylic acid (ester) copolymer, and is purchased from Wuhan Huazhike scientific biotechnology, Inc.
The sodium salt is organic sodium salt and inorganic sodium salt; the weight ratio of the organic sodium salt to the inorganic sodium salt is 1: 39.
the organic sodium salt is EDTA-2Na, the solubility of the EDTA-2Na in water is 11g/100ml, and the testing temperature is 22 ℃; the inorganic sodium salt is NaCl, the solubility of NaCl in water is 36g/100ml, and the test temperature is 22 ℃.
The polyhydric alcohol and the derivatives thereof are glycerol and ethylhexyl glycerol, and the weight ratio of the glycerol to the ethylhexyl glycerol is 128: 2.
the preservative is phenoxyethanol, and the CAS number is 122-99-6.
The organic acid is citric acid, and the CAS number is 77-92-9.
The second aspect of the embodiment provides a preparation method of an antibacterial and anti-inflammatory facial cleanser, which comprises the following specific preparation steps:
s1, weighing phase A raw materials according to the formula amount, uniformly mixing, heating to 80 ℃, and uniformly stirring at constant temperature to obtain a mixture I;
s2, weighing the phase B raw materials according to the formula amount, and uniformly mixing to obtain a mixture II;
s3, weighing the C-phase raw materials according to the formula amount, and uniformly mixing to obtain a mixture III;
and S4, cooling the mixture I to 45 ℃, adding the mixture II and the mixture III into the mixture I, uniformly stirring, and cooling to obtain a finished product.
Example 3.
The embodiment provides an antibacterial and anti-inflammatory facial cleanser, which comprises the following raw materials in percentage by weight:
phase A: 10% of natural plant components, 10% of foaming agent, 1% of stearate, 1% of fatty chain amino acid derivative and 0.2% of film forming agent;
phase B: 1% of sodium salt;
and C phase: 6% of polyhydric alcohol and derivatives thereof, 0.3% of preservative, 0.2% of organic acid and the balance of water.
Wherein the raw material weight sum of the phase A, the phase B and the phase C is 100 percent.
The natural plant components are soapberry peel extracts, the saponin content of the soapberry peel extracts is 15% by mass, and the soapberry peel extracts are purchased from Guangdong cyanine extraction Biotech limited company.
The foaming agent is a sulfonate compound, and the sulfonate compound is disodium lauryl sulfosuccinate and sodium cocoyl methyl taurate. The CAS number of the disodium lauryl sulfosuccinate is 19040-44-9, and the CAS number of the sodium cocoyl methyl taurate is 12765-39-8.
The weight ratio of the disodium lauryl sulfosuccinate to the sodium cocoyl methyl taurate is 2: 1.
the stearate is glyceryl stearate and PEG-100 stearate.
The weight ratio of the glycerol stearate to the PEG-100 stearate is 1: 1. glycerol stearate has CAS number 85666-92-8, PEG-100 stearate has CAS number 9004-99-3.
The fatty chain amino acid derivative is potassium cocoyl glycinate, and the CAS number is 301341-58-2.
The film-forming agent is acrylic acid (ester) copolymer, and is purchased from Wuhan Huazhike scientific biotechnology, Inc.
The sodium salt is organic sodium salt and inorganic sodium salt; the weight ratio of the organic sodium salt to the inorganic sodium salt is 1: 9.
the organic sodium salt is EDTA-2Na, the solubility of the EDTA-2Na in water is 11g/100ml, and the testing temperature is 22 ℃; the inorganic sodium salt is NaCl, the solubility of NaCl in water is 36g/100ml, and the test temperature is 22 ℃.
The polyhydric alcohol and the derivatives thereof are glycerol and ethylhexyl glycerol, and the weight ratio of the glycerol to the ethylhexyl glycerol is 58: 2.
the preservative is phenoxyethanol, and the CAS number is 122-99-6.
The organic acid is citric acid, and the CAS number is 77-92-9.
The second aspect of the embodiment provides a preparation method of an antibacterial and anti-inflammatory facial cleanser, which comprises the following specific preparation steps:
s1, weighing phase A raw materials according to the formula amount, uniformly mixing, heating to 80 ℃, and uniformly stirring at constant temperature to obtain a mixture I;
s2, weighing the phase B raw materials according to the formula amount, and uniformly mixing to obtain a mixture II;
s3, weighing the C-phase raw materials according to the formula amount, and uniformly mixing to obtain a mixture III;
and S4, cooling the mixture I to 45 ℃, adding the mixture II and the mixture III into the mixture I, uniformly stirring, and cooling to obtain a finished product.
Example 4 [ Sapindus mukurossi extract added in small amount ]
The embodiment provides an antibacterial and anti-inflammatory facial cleanser, which comprises the following raw materials in percentage by weight:
phase A: 5% of natural plant components, 10% of foaming agents, 3% of stearate, 3% of fatty chain amino acid derivatives and 0.5% of film forming agents;
phase B: 2.5 percent of sodium salt;
and C phase: 10% of polyhydric alcohol and derivatives thereof, 0.5% of preservative, 0.5% of organic acid and the balance of water.
Wherein the raw material weight sum of the phase A, the phase B and the phase C is 100 percent.
The natural plant components are soapberry peel extracts, the saponin content of the soapberry peel extracts is 15% by mass, and the soapberry peel extracts are purchased from Guangdong cyanine extraction Biotech limited company.
The foaming agent is a sulfonate compound, and the sulfonate compound is disodium lauryl sulfosuccinate and sodium cocoyl methyl taurate. The CAS number of the disodium lauryl sulfosuccinate is 19040-44-9, and the CAS number of the sodium cocoyl methyl taurate is 12765-39-8.
The weight ratio of the disodium lauryl sulfosuccinate to the sodium cocoyl methyl taurate is 2: 1.
the stearate is glyceryl stearate and PEG-100 stearate.
The weight ratio of the glycerol stearate to the PEG-100 stearate is 1: 1. glycerol stearate has CAS number 85666-92-8, PEG-100 stearate has CAS number 9004-99-3.
The fatty chain amino acid derivative is potassium cocoyl glycinate, and the CAS number is 301341-58-2.
The film-forming agent is acrylic acid (ester) copolymer, and is purchased from Wuhan Huazhike scientific biotechnology, Inc.
The sodium salt is organic sodium salt and inorganic sodium salt; the weight ratio of the organic sodium salt to the inorganic sodium salt is 1: 24.
the organic sodium salt is EDTA-2Na, the solubility of the EDTA-2Na in water is 11g/100ml, and the testing temperature is 22 ℃; the inorganic sodium salt is NaCl, the solubility of NaCl in water is 36g/100ml, and the test temperature is 22 ℃.
The polyhydric alcohol and the derivatives thereof are glycerol and ethylhexyl glycerol, and the weight ratio of the glycerol to the ethylhexyl glycerol is 98: 2.
the preservative is phenoxyethanol, and the CAS number is 122-99-6.
The organic acid is citric acid, and the CAS number is 77-92-9.
The second aspect of the embodiment provides a preparation method of an antibacterial and anti-inflammatory facial cleanser, which comprises the following specific preparation steps:
s1, weighing phase A raw materials according to the formula amount, uniformly mixing, heating to 80 ℃, and uniformly stirring at constant temperature to obtain a mixture I;
s2, weighing the phase B raw materials according to the formula amount, and uniformly mixing to obtain a mixture II;
s3, weighing the C-phase raw materials according to the formula amount, and uniformly mixing to obtain a mixture III;
and S4, cooling the mixture I to 45 ℃, adding the mixture II and the mixture III into the mixture I, uniformly stirring, and cooling to obtain a finished product.
Example 5 [ plant ingredients with Low saponin content ]
The embodiment provides an antibacterial and anti-inflammatory facial cleanser, which comprises the following raw materials in percentage by weight:
phase A: 45% of natural plant component, 10% of foaming agent, 3% of stearate, 3% of fatty chain amino acid derivative and 0.5% of film forming agent;
phase B: 2.5 percent of sodium salt;
and C phase: 10% of polyhydric alcohol and derivatives thereof, 0.5% of preservative, 0.5% of organic acid and the balance of water.
Wherein the raw material weight sum of the phase A, the phase B and the phase C is 100 percent.
The natural plant component is a yam rhizome extract, and the mass content of saponin in the yam rhizome extract is 0.3%.
The rhizoma Dioscoreae Septemlobae extract is purchased from Fufeng Sonote Biotech, Inc.
The foaming agent is a sulfonate compound, and the sulfonate compound is disodium lauryl sulfosuccinate and sodium cocoyl methyl taurate. The CAS number of the disodium lauryl sulfosuccinate is 19040-44-9, and the CAS number of the sodium cocoyl methyl taurate is 12765-39-8.
The weight ratio of the disodium lauryl sulfosuccinate to the sodium cocoyl methyl taurate is 2: 1.
the stearate is glyceryl stearate and PEG-100 stearate.
The weight ratio of the glycerol stearate to the PEG-100 stearate is 1: 1. glycerol stearate has CAS number 85666-92-8, PEG-100 stearate has CAS number 9004-99-3.
The fatty chain amino acid derivative is potassium cocoyl glycinate, and the CAS number is 301341-58-2.
The film-forming agent is acrylic acid (ester) copolymer, and is purchased from Wuhan Huazhike scientific biotechnology, Inc.
The sodium salt is organic sodium salt and inorganic sodium salt; the weight ratio of the organic sodium salt to the inorganic sodium salt is 1: 24.
the organic sodium salt is EDTA-2Na, the solubility of the EDTA-2Na in water is 11g/100ml, and the testing temperature is 22 ℃; the inorganic sodium salt is NaCl, the solubility of NaCl in water is 36g/100ml, and the test temperature is 22 ℃.
The polyhydric alcohol and the derivatives thereof are glycerol and ethylhexyl glycerol, and the weight ratio of the glycerol to the ethylhexyl glycerol is 98: 2.
the preservative is phenoxyethanol, and the CAS number is 122-99-6.
The organic acid is citric acid, and the CAS number is 77-92-9.
The second aspect of the embodiment provides a preparation method of an antibacterial and anti-inflammatory facial cleanser, which comprises the following specific preparation steps:
s1, weighing phase A raw materials according to the formula amount, uniformly mixing, heating to 80 ℃, and uniformly stirring at constant temperature to obtain a mixture I;
s2, weighing the phase B raw materials according to the formula amount, and uniformly mixing to obtain a mixture II;
s3, weighing the C-phase raw materials according to the formula amount, and uniformly mixing to obtain a mixture III;
and S4, cooling the mixture I to 45 ℃, adding the mixture II and the mixture III into the mixture I, uniformly stirring, and cooling to obtain a finished product.
Example 6 [ without addition of fatty chain amino acid derivatives ]
The embodiment provides an antibacterial and anti-inflammatory facial cleanser, which comprises the following raw materials in percentage by weight:
phase A: 25% of natural plant components, 10% of foaming agent, 3% of stearate and 0.5% of film forming agent;
phase B: 2.5 percent of sodium salt;
and C phase: 10% of polyhydric alcohol and derivatives thereof, 0.5% of preservative, 0.5% of organic acid and the balance of water.
Wherein the raw material weight sum of the phase A, the phase B and the phase C is 100 percent.
The natural plant components are soapberry peel extracts, the saponin content of the soapberry peel extracts is 15% by mass, and the soapberry peel extracts are purchased from Guangdong cyanine extraction Biotech limited company.
The foaming agent is a sulfonate compound, and the sulfonate compound is disodium lauryl sulfosuccinate and sodium cocoyl methyl taurate. The CAS number of the disodium lauryl sulfosuccinate is 19040-44-9, and the CAS number of the sodium cocoyl methyl taurate is 12765-39-8.
The weight ratio of the disodium lauryl sulfosuccinate to the sodium cocoyl methyl taurate is 2: 1.
the stearate is glyceryl stearate and PEG-100 stearate.
The weight ratio of the glycerol stearate to the PEG-100 stearate is 1: 1. glycerol stearate has CAS number 85666-92-8, PEG-100 stearate has CAS number 9004-99-3.
The film-forming agent is acrylic acid (ester) copolymer, and is purchased from Wuhan Huazhike scientific biotechnology, Inc.
The sodium salt is organic sodium salt and inorganic sodium salt; the weight ratio of the organic sodium salt to the inorganic sodium salt is 1: 24.
the organic sodium salt is EDTA-2Na, the solubility of the EDTA-2Na in water is 11g/100ml, and the testing temperature is 22 ℃; the inorganic sodium salt is NaCl, the solubility of NaCl in water is 36g/100ml, and the test temperature is 22 ℃.
The polyhydric alcohol and the derivatives thereof are glycerol and ethylhexyl glycerol, and the weight ratio of the glycerol to the ethylhexyl glycerol is 98: 2.
the preservative is phenoxyethanol, and the CAS number is 122-99-6.
The organic acid is citric acid, and the CAS number is 77-92-9.
The second aspect of the embodiment provides a preparation method of an antibacterial and anti-inflammatory facial cleanser, which comprises the following specific preparation steps:
s1, weighing phase A raw materials according to the formula amount, uniformly mixing, heating to 80 ℃, and uniformly stirring at constant temperature to obtain a mixture I;
s2, weighing the phase B raw materials according to the formula amount, and uniformly mixing to obtain a mixture II;
s3, weighing the C-phase raw materials according to the formula amount, and uniformly mixing to obtain a mixture III;
and S4, cooling the mixture I to 45 ℃, adding the mixture II and the mixture III into the mixture I, uniformly stirring, and cooling to obtain a finished product.
Example 7 [ replacement of sodium cocoyl methyl taurate with octadecyl diester Quaternary ammonium salt ]
The embodiment provides an antibacterial and anti-inflammatory facial cleanser, which comprises the following raw materials in percentage by weight:
phase A: 25% of natural plant components, 10% of foaming agent, 3% of stearate, 3% of fatty chain amino acid derivative and 0.5% of film forming agent;
phase B: 2.5 percent of sodium salt;
and C phase: 10% of polyhydric alcohol and derivatives thereof, 0.5% of preservative, 0.5% of organic acid and the balance of water.
Wherein the raw material weight sum of the phase A, the phase B and the phase C is 100 percent.
The natural plant components are soapberry peel extracts, the saponin content of the soapberry peel extracts is 15% by mass, and the soapberry peel extracts are purchased from Guangdong cyanine extraction Biotech limited company.
The foaming agent is disodium lauryl sulfosuccinate and octadecyl diester quaternary ammonium salt. The CAS number of the disodium lauryl sulfosuccinate is 19040-44-9, and the octadecyl diester quaternary ammonium salt is purchased from purification technology of Henan province.
The weight ratio of the disodium lauryl sulfosuccinate to the sodium cocoyl methyl taurate is 2: 1.
the stearate is glyceryl stearate and PEG-100 stearate.
The weight ratio of the glycerol stearate to the PEG-100 stearate is 1: 1. glycerol stearate has CAS number 85666-92-8, PEG-100 stearate has CAS number 9004-99-3.
The fatty chain amino acid derivative is potassium cocoyl glycinate, and the CAS number is 301341-58-2.
The film-forming agent is acrylic acid (ester) copolymer, and is purchased from Wuhan Huazhike scientific biotechnology, Inc.
The sodium salt is organic sodium salt and inorganic sodium salt; the weight ratio of the organic sodium salt to the inorganic sodium salt is 1: 24.
the organic sodium salt is EDTA-2Na, the solubility of the EDTA-2Na in water is 11g/100ml, and the testing temperature is 22 ℃; the inorganic sodium salt is NaCl, the solubility of NaCl in water is 36g/100ml, and the test temperature is 22 ℃.
The polyhydric alcohol and the derivatives thereof are glycerol and ethylhexyl glycerol, and the weight ratio of the glycerol to the ethylhexyl glycerol is 98: 2.
the preservative is phenoxyethanol, and the CAS number is 122-99-6.
The organic acid is citric acid, and the CAS number is 77-92-9.
The second aspect of the embodiment provides a preparation method of an antibacterial and anti-inflammatory facial cleanser, which comprises the following specific preparation steps:
s1, weighing phase A raw materials according to the formula amount, uniformly mixing, heating to 80 ℃, and uniformly stirring at constant temperature to obtain a mixture I;
s2, weighing the phase B raw materials according to the formula amount, and uniformly mixing to obtain a mixture II;
s3, weighing the C-phase raw materials according to the formula amount, and uniformly mixing to obtain a mixture III;
and S4, cooling the mixture I to 45 ℃, adding the mixture II and the mixture III into the mixture I, uniformly stirring, and cooling to obtain a finished product.
Example 8 [ replacement of Glycerol by 1, 4-butanediol ]
The embodiment provides an antibacterial and anti-inflammatory facial cleanser, which comprises the following raw materials in percentage by weight:
phase A: 25% of natural plant components, 10% of foaming agent, 3% of stearate, 3% of fatty chain amino acid derivative and 0.5% of film forming agent;
phase B: 2.5 percent of sodium salt;
and C phase: 10% of polyhydric alcohol and derivatives thereof, 0.5% of preservative, 0.5% of organic acid and the balance of water.
Wherein the raw material weight sum of the phase A, the phase B and the phase C is 100 percent.
The natural plant components are soapberry peel extracts, the saponin content of the soapberry peel extracts is 15% by mass, and the soapberry peel extracts are purchased from Guangdong cyanine extraction Biotech limited company.
The foaming agent is a sulfonate compound, and the sulfonate compound is disodium lauryl sulfosuccinate and sodium cocoyl methyl taurate. The CAS number of the disodium lauryl sulfosuccinate is 19040-44-9, and the CAS number of the sodium cocoyl methyl taurate is 12765-39-8.
The weight ratio of the disodium lauryl sulfosuccinate to the sodium cocoyl methyl taurate is 2: 1.
the stearate is glyceryl stearate and PEG-100 stearate.
The weight ratio of the glycerol stearate to the PEG-100 stearate is 1: 1. glycerol stearate has CAS number 85666-92-8, PEG-100 stearate has CAS number 9004-99-3.
The fatty chain amino acid derivative is potassium cocoyl glycinate, and the CAS number is 301341-58-2.
The film-forming agent is acrylic acid (ester) copolymer, and is purchased from Wuhan Huazhike scientific biotechnology, Inc.
The sodium salt is organic sodium salt and inorganic sodium salt; the weight ratio of the organic sodium salt to the inorganic sodium salt is 1: 24.
the organic sodium salt is EDTA-2Na, the solubility of the EDTA-2Na in water is 11g/100ml, and the testing temperature is 22 ℃; the inorganic sodium salt is NaCl, the solubility of NaCl in water is 36g/100ml, and the test temperature is 22 ℃.
The polyhydric alcohol and the derivatives thereof are 1, 4-butanediol and ethylhexylglycerin, and the weight ratio of the 1, 4-butanediol to the ethylhexylglycerin is 98: 2.
the preservative is phenoxyethanol, and the CAS number is 122-99-6.
The organic acid is citric acid, and the CAS number is 77-92-9.
The second aspect of the embodiment provides a preparation method of an antibacterial and anti-inflammatory facial cleanser, which comprises the following specific preparation steps:
s1, weighing phase A raw materials according to the formula amount, uniformly mixing, heating to 80 ℃, and uniformly stirring at constant temperature to obtain a mixture I;
s2, weighing the phase B raw materials according to the formula amount, and uniformly mixing to obtain a mixture II;
s3, weighing the C-phase raw materials according to the formula amount, and uniformly mixing to obtain a mixture III;
and S4, cooling the mixture I to 45 ℃, adding the mixture II and the mixture III into the mixture I, uniformly stirring, and cooling to obtain a finished product.
Performance test method
And (3) stability testing:
the face creams prepared in the embodiments 1-8 are placed at the conditions of (1)50 ℃, (2)40 ℃, (3)26 ℃, (4) -4 ℃ for one week in sequence, whether the face creams are layered or discolored or not is observed, 10 parallel samples of the face creams in each embodiment are taken for detection, the number X of the samples with the layered or discolored phenomena after the test is recorded, and the defined effective rate is (10-X)/10X 100%.
Cleaning ability:
dissolving 1g of the facial cleanser prepared in the examples 1 to 8 in 20mL of water, uniformly stirring, dripping the mixed solution on the surface of coated paper, dripping oil stains (simulating facial stains) on the surface of the coated paper, standing for 15s, slightly looping by finger abdomen, observing the removal effect of the oil stains, defining the cleaning capacity as 1-3 grade, and specifically:
level 1: the oil stain removal area is more than 95 percent;
and 2, stage: the oil stain removal area is 90-95%;
and 3, level: the oil stain removing area is less than 90%.
Water replenishing capacity:
100 healthy facial volunteers were selected and divided into 10 groups, and facial cleansing was performed using the facial cleansers prepared in examples 1 to 8 of the present invention, and the skin moisture content before and after facial cleansing was measured using an intelligent skin moisture meter of quanzhou yashi trade limited company, and the moisturizing intensity was calculated as (skin moisture content after facial cleansing-skin moisture content before facial cleansing)/skin moisture content before facial cleansing × 100%. The water replenishing strength is defined as excellent when being more than 50 percent, good when being 20-50 percent and poor when being less than 20 percent.
Antibacterial ability:
the antibacterial ability of the face cleansers prepared in examples 1 to 3 was tested with reference to technical standards for safety of cosmetics (2015 edition), and the hygienic indexes of the face cleansers of examples 1 to 3 were all in accordance with the regulations of technical standards for safety of cosmetics.
Performance test data
TABLE 1 Performance test results
Effective rate% | Cleaning power/grade | Water replenishing ability | |
Example 1 | 100% | 1 | Superior food |
Example 2 | 100% | 1 | Superior food |
Example 3 | 100% | 1 | Superior food |
Example 4 | 80% | 2 | Good wine |
Example 5 | 70% | 3 | Difference (D) |
Example 6 | 90% | 1 | Good wine |
Example 7 | 80% | 1 | Good wine |
Example 8 | 80% | 2 | Difference (D) |
Finally, it is pointed out that the foregoing examples are illustrative only, serving to explain some of the characteristics of the process according to the invention. The appended claims are intended to claim as broad a scope as is contemplated, and the examples presented herein are merely illustrative of selected implementations in accordance with all possible combinations of examples. Accordingly, it is applicants' intention that the appended claims are not to be limited by the choice of examples illustrating features of the invention. Also, where numerical ranges are used in the claims, subranges therein are included, and variations in these ranges are also to be construed as possible being covered by the appended claims.
Claims (10)
1. The antibacterial and anti-inflammatory facial cleanser is characterized by comprising the following raw materials in percentage by weight:
phase A: 10-40% of natural plant components, 1-20% of foaming agent, 0.1-5% of stearate, 1-5% of fatty chain amino acid derivative and 0.1-2% of film-forming agent;
phase B: 0.01 to 6 percent of sodium salt;
and C phase: 4-17% of polyhydric alcohol and derivatives thereof, 0.1-1% of preservative, 0.1-1% of organic acid and the balance of water.
Wherein the sum of the weight percentages of the phase A, the phase B and the phase C is 100 percent.
2. The facial cleanser with antibacterial and anti-inflammatory effects as claimed in claim 1, wherein the mass content of glycosides in the natural plant components is greater than 10%.
3. The antibacterial and anti-inflammatory facial cleanser according to claim 1, wherein the natural plant components comprise at least one of soapberry peel extract, sasanqua cake extract, Chinese honeylocust fruit extract, ginseng extract, licorice extract, bupleurum extract, platycodon grandiflorum extract, alisma orientale extract, ganoderma lucidum extract, tea extract and sea cucumber extract.
4. The facial cleanser with antibacterial and anti-inflammatory effects as claimed in claim 1, wherein the foaming agent comprises at least one of sulfonate compounds, fatty alcohol-polyoxyethylene ether, alkyl glycoside and amino acid derivatives.
5. An antibacterial and anti-inflammatory facial cleanser according to claim 1, wherein said stearate comprises at least one of polyglyceryl-diisostearate, sorbitan tristearate, glyceryl stearate, polyethylene glycol distearate, PEG-100 stearate, polyoxyethylene stearate, isopropyl stearate, pentaerythritol tetraisostearate, polyoxyethylene sorbitol stearate, and cetearyl stearate.
6. An antibacterial and anti-inflammatory facial cleanser according to claim 1, wherein said fatty chain amino acid derivative comprises at least one of lauroyl glutamate, cocoyl glycinate, cocoyl alanate, stearoyl glutamate, palmitoyl glutamate, cocoyl arginine ester, cocoyl potassium glycinate, lauroyl sarcosinate, cocoyl arginine salt, palmitoyl sarcosinate.
7. The facial cleanser with antibacterial and anti-inflammatory effects as claimed in claim 1, wherein the solubility of the sodium salt in water is 10-40g/100ml, and the testing temperature is 22 ℃.
9. The facial cleanser with antibacterial and anti-inflammatory effects as claimed in claim 1, wherein said organic acid comprises at least one of phosphoric acid, citric acid, tartaric acid, maleic acid and malic acid.
10. A method for preparing the antibacterial and anti-inflammatory facial cleanser according to any one of claims 1 to 9, wherein the preparation method comprises the following steps:
s1, weighing phase A raw materials according to the formula amount, uniformly mixing, heating to 70-85 ℃, and uniformly stirring at constant temperature to obtain a mixture I;
s2, weighing the phase B raw materials according to the formula amount, and uniformly mixing to obtain a mixture II;
s3, weighing the C-phase raw materials according to the formula amount, and uniformly mixing to obtain a mixture III;
s4, cooling the first mixture to 35-48 ℃, adding the second mixture and the third mixture into the first mixture, uniformly stirring, and cooling to obtain a finished product.
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Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050220742A1 (en) * | 2004-03-31 | 2005-10-06 | Breen Ed V | Compositions and methods for maintaining eyelid hygiene |
CN111374918A (en) * | 2020-03-19 | 2020-07-07 | 广州恒芳生物科技有限公司 | Cannabidiol cleaning product and preparation method thereof |
CN111388370A (en) * | 2020-04-02 | 2020-07-10 | 广州市逸轩精细化工有限公司 | Hair and bath two-in-one washing and protecting lotion for children and preparation method thereof |
CN112370395A (en) * | 2020-12-14 | 2021-02-19 | 广州艾蓓生物科技有限公司 | Amino acid facial cleanser and preparation method thereof |
CN112807249A (en) * | 2021-01-13 | 2021-05-18 | 上海易亨化工有限公司 | Application of water-soluble almond oil in facial cleanser |
-
2021
- 2021-06-17 CN CN202110676280.8A patent/CN113499302A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050220742A1 (en) * | 2004-03-31 | 2005-10-06 | Breen Ed V | Compositions and methods for maintaining eyelid hygiene |
CN111374918A (en) * | 2020-03-19 | 2020-07-07 | 广州恒芳生物科技有限公司 | Cannabidiol cleaning product and preparation method thereof |
CN111388370A (en) * | 2020-04-02 | 2020-07-10 | 广州市逸轩精细化工有限公司 | Hair and bath two-in-one washing and protecting lotion for children and preparation method thereof |
CN112370395A (en) * | 2020-12-14 | 2021-02-19 | 广州艾蓓生物科技有限公司 | Amino acid facial cleanser and preparation method thereof |
CN112807249A (en) * | 2021-01-13 | 2021-05-18 | 上海易亨化工有限公司 | Application of water-soluble almond oil in facial cleanser |
Non-Patent Citations (1)
Title |
---|
龙德权: "无患子洗面奶的制备", 《广东化工》 * |
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