CN113476741A - Transcranial direct current stimulation device and working method - Google Patents
Transcranial direct current stimulation device and working method Download PDFInfo
- Publication number
- CN113476741A CN113476741A CN202110675185.6A CN202110675185A CN113476741A CN 113476741 A CN113476741 A CN 113476741A CN 202110675185 A CN202110675185 A CN 202110675185A CN 113476741 A CN113476741 A CN 113476741A
- Authority
- CN
- China
- Prior art keywords
- stimulation
- module
- current
- detection module
- electrode
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
- A61B5/0531—Measuring skin impedance
Abstract
The invention discloses a transcranial direct current stimulation device and a working method thereof, and the device comprises a processing unit arranged in a shell, wherein a stimulation electrode jack, a system display screen, a system power key, a current adjusting knob and a control key are arranged on the shell, the stimulation electrode jack, the system display screen, the system power key, the current adjusting knob and the control key are all connected with the processing unit, the stimulation electrode jack is provided with an anode and a cathode, the current and time are controlled by the processing unit arranged in the shell, a patient is treated by the electrode inserted into the stimulation electrode jack, an impedance detection module is used for monitoring whether the stimulation electrode is contacted with the scalp, and a current detection module is used for detecting whether the current is overlarge.
Description
Technical Field
The invention belongs to the field of medical instruments, and particularly relates to a transcranial direct current stimulation device and a working method thereof.
Background
The application is a divisional application with application number 201611024708.6 and the name of the invention is a transcranial direct current stimulation device and a working method, and the disclosure of the mother case is fully introduced.
With the development of society and the accelerated aging process of population, the incidence of some nervous system diseases such as alzheimer disease (senile dementia) and the like is increasing. According to statistics, at present, the number of Alzheimer's disease patients in China is up to 500 thousands, 30 thousands of new cases are found in each year on average, and more than 1000 thousands of Alzheimer's disease patients in China are expected to exist by 2030. Alzheimer's disease patients have clinical manifestations of memory impairment, executive dysfunction, appetite, etc., thus seriously affecting the normal lives of the patients.
Transcranial direct current stimulation (tDCS) is a non-invasive, low-cost, and easy-to-use technique. Two electrodes (usually a cathode and an anode) are attached to different areas of a skull, and constant and low-intensity (1-2 mA) direct current is transmitted to a specific area in the cranium, so that the excitability of cerebral cortical neurons is improved or reduced, and further the brain functionality is changed, and the electrode can be used for clinical treatment research of diseases such as Alzheimer's disease, Parkinson's disease, cognitive disorder and the like.
The transcranial direct current stimulation device provided by the existing patent has many defects, for example, the transcranial direct current stimulation device introduced in patent document 201410597221.1 cannot detect load impedance, and the safety of the stimulation device is not high; the transcranial direct current stimulation device described in patent No. 201210042918.3, while capable of measuring load impedance, allows the load impedance to fall short of clinical requirements. In addition, these transcranial direct current stimulation devices cannot store information such as current intensity, electrode polarity, and the region of the stimulated brain, and it is difficult to provide effective reference for clinical analysis or further treatment. When one-time transcranial direct current stimulation lasts longer, stimulation needs to be stopped, and a battery needs to be replaced, so that the effect of transcranial direct current stimulation is affected.
Disclosure of Invention
The invention aims to overcome the defects and provides a transcranial direct current stimulation device and a working method thereof, which can measure the impedance of a stimulated brain region in real time in the electrical stimulation process, record and store information such as current intensity, electrode polarity, the stimulated brain region part, the impedance of the stimulated brain region and the like, and prolong the service time of a battery of the electrical stimulation device.
In order to achieve the above object, a transcranial direct current stimulation device comprises,
the transcranial direct current stimulation device is used for delivering constant and low-intensity direct current of 1-2 mA to specific intracranial regions by attaching two stimulation electrodes to different regions of the skull, so that the excitability of cerebral cortical neurons is improved or reduced, and the brain functionality is further changed, and the transcranial direct current stimulation device is used for clinical treatment research of diseases such as Alzheimer's disease, Parkinson's disease, cognitive disorder and the like; the device comprises a processing unit arranged in a shell (1), wherein a stimulation electrode jack (2), a system display screen (3), a system power key (4), a current adjusting knob (5) and a control key are arranged on the shell (1), the stimulation electrode jack (2), the system display screen (3), the system power key (4), the current adjusting knob (5) and the control key are all connected with the processing unit, and the stimulation electrode jack (2) is provided with a positive electrode and a negative electrode;
the processing unit comprises a microprocessor MCU with an A/D conversion module, the microprocessor MCU is connected with an operation module and a liquid crystal display module, the microprocessor MCU is connected with a battery electric quantity detection module, an impedance detection module and a current detection module through the A/D conversion module, the battery electric quantity detection module is connected with a power supply module, the power supply module is connected with a boosting module, the boosting module is connected with a constant current source module, the constant current source module is connected with the current detection module and a stimulation module, and the stimulation module is connected with the impedance detection module;
the constant current source module is connected with the negative electrode of the stimulating electrode jack (2), the boosting module is connected with the positive electrode of the stimulating electrode jack (2), the operation module is connected with the control key and the current adjusting knob (5), and the liquid crystal display module is connected with the system display screen (3);
the constant current source module consists of a controllable precise voltage-stabilizing source and an MOSFET (metal-oxide-semiconductor field effect transistor), is used for outputting direct current stimulation with constant intensity, and has continuously adjustable stimulation current intensity within an allowable range;
the impedance detection module is used for measuring the impedance for stimulating the brain region;
the current detection module is used for guiding the setting of the intensity of the stimulation current before stimulation and monitoring the magnitude of the stimulation current in the stimulation process; the current intensity flowing through the stimulating electrodes and the impedance between the stimulating electrodes are converted into corresponding analog voltage signals through a current detection module and an impedance detection module, the analog voltage signals are converted into digital signals through an A/D module in a microprocessor MCU, and corresponding current values and impedance values are calculated; when the stimulation current exceeds the allowed maximum value, on one hand, the analog voltage converted by the current detection module is compared with the preset voltage by the comparator, the power supply is quickly cut off, and meanwhile, the I/O port of the microprocessor MCU sends a signal to cut off the connection between the constant current source and the stimulation electrode, so that double protection is achieved, and sound and light alarm is carried out; if the calculated impedance value is far larger than the normal value, the stimulation electrode is determined not to be tightly contacted with the scalp, and the liquid crystal display screen can prompt; the calculated current value and the calculated impedance value are displayed on a system display screen in real time on one hand, and are transmitted to an upper computer through a Bluetooth module to be stored on the other hand;
the upper computer is based on software for monitoring transcranial direct current stimulation and can display the recorded stimulation current intensity and the stimulation brain area impedance curve in real time; the stimulation information of any previous time point can be inquired as well as the current intensity sent by the Bluetooth module, the polarity of the electrode, the brain stimulation part and the impedance information of the brain stimulation area during each stimulation;
in addition, the overcurrent protection and alarm module, the liquid crystal display module and the operation module are directly connected with an I/O port of the microprocessor MCU;
the current detection module is connected with the current detection module through the comparator on one hand, and is connected with an I/O port of the microprocessor MCU on the other hand, when the stimulation current exceeds the allowed maximum current, the connection of a power supply and a constant current source with a stimulation electrode can be quickly cut off, double protection is provided, and sound and light alarm is performed;
the boosting module boosts the voltage output by the power supply module to a required size by using a DC-DC conversion chip, and provides support for stimulation of current output by the constant current source module; the conversion efficiency is effectively improved, the power consumption is reduced, the working time of the battery is prolonged, and the transcranial direct current stimulation for a longer time can be met; the boosting module comprises a DC-DC conversion chip, wherein a pin 1 of the DC-DC conversion chip is connected with the anode of a high-speed switch diode D and one end of an inductor L, a pin 2 is grounded, a pin 3 is grounded through a first capacitor CT, a pin 4 is grounded, a pin 5 is connected with one ends of a first resistor R1 and a second resistor R2, a pin 6 is connected with one end of a third resistor RSC, the anode of a third capacitor C1 and the anode Vin of a battery, a pin 7 is connected with the other end of the third resistor RSC, the other end of the inductor L and the first end of a fourth resistor R, a pin 8 is connected with the other end of the fourth resistor R, the cathode of the high-speed switch diode D is connected with the other end of the second resistor R2, the anode of a second capacitor C0 and a boosted output voltage Vout, the other end of the second resistor R1 is connected with the cathode of the second capacitor C0 and the cathode of the third capacitor C1 and grounded, the conversion efficiency is increased by changing the sizes of the resistor RSC, the inductor L and the first capacitor CT.
In the transcranial direct current stimulation device, the control keys comprise a determination key (6), an upper selection key (7) and a lower selection key (8).
A working method of a transcranial direct current stimulation device comprises the following steps:
step one, pressing a power key, initializing a microprocessor MCU after a system is started, and initializing a peripheral chip;
inserting a lead connected with a stimulation electrode into an electrode jack of the device, and selecting a stimulation part;
step three, attaching the stimulation electrode to a stimulation part selected by the scalp, detecting whether the stimulation electrode is tightly contacted with the scalp by the impedance detection module, if so, carrying out the next step, otherwise, prompting on a system display screen, and carrying out peripheral chip initialization again;
step four, setting the stimulation current intensity, setting the stimulation time and starting a confirming key;
fifthly, the system starts to stimulate, and data acquisition is carried out through an impedance detection module and a current detection module and displayed on a system display screen;
step six, the current detection module judges whether the current exceeds the maximum value, if not, stimulation is continued, if yes, an alarm is given, and stimulation is stopped;
and step seven, judging whether the stimulation time is finished or not by the microprocessor MCU, if not, continuing the stimulation, and if so, stopping the stimulation.
And the data in the fifth step are transmitted to the upper computer through Bluetooth. Compared with the prior art, the device disclosed by the invention has the advantages that the current and time are controlled by the processing unit arranged in the shell, the electrode inserted into the stimulating electrode jack is used for treating a patient, whether the stimulating electrode is contacted with the scalp or not is monitored by the impedance detection module, and whether the current is overlarge or not is detected by the current detection module.
Furthermore, the invention redesigns the boosting module, ensures that the device meets the requirement, reduces the power consumption, enables the battery to meet the transcranial direct current stimulation for a longer time, and avoids the stimulation effect from being influenced by the interruption of stimulation due to the replacement of the battery.
Furthermore, the invention is connected with the upper computer through the Bluetooth module, so that the stimulation data can be stored in the mobile phone, and the stimulation data information at any time point can be inquired. In the method, under the support of the battery and the booster circuit, the constant current source can provide constant direct current stimulation for the load between the stimulation electrodes; the current intensity flowing through the stimulating electrodes and the impedance between the stimulating electrodes are converted into corresponding analog voltage signals through a current detection circuit and an impedance detection circuit, the analog voltage signals are converted into digital signals through an A/D module in a microprocessor MCU (microprogrammed control Unit), and corresponding current values and impedance values are calculated; when the stimulation current exceeds the allowed maximum value, on one hand, the analog voltage converted by the current detection circuit is compared with the preset voltage by the comparator, the power supply can be quickly cut off, and meanwhile, the I/O port of the microprocessor sends a signal to cut off the connection between the constant current source and the stimulation electrode, so that double protection is achieved, and sound and light alarm is performed; if the calculated impedance value is far larger than the normal value, the stimulation electrode is determined not to be tightly contacted with the scalp, and the liquid crystal display screen can prompt; the calculated current value and the calculated impedance value are displayed on a liquid crystal display screen in real time on one hand, and are transmitted to an upper computer for storage through Bluetooth on the other hand.
Drawings
FIG. 1 is a schematic diagram of the circuit structure of the present invention;
FIG. 2 is a schematic external view of a product according to the present invention;
FIG. 3 is a circuit diagram of a boost module of the present invention;
FIG. 4 is a software flow diagram of the present invention;
FIG. 5 is a flow chart of the operation of the present invention;
wherein, 1, a shell; 2. a stimulation electrode jack; 3. a system display screen; 4. a system power key; 5. a current adjusting knob; 6. determining a key; 7. an upper selection key; 8. the selection key is pressed.
Detailed Description
The present invention will be further described with reference to fig. 1 to 5.
Referring to fig. 1 and 2, a transcranial direct current stimulation device comprises a processing unit arranged in a shell 1, wherein a stimulation electrode jack 2, a system display screen 3, a system power key 4, a current adjusting knob 5 and a control key are arranged on the shell 1, the stimulation electrode jack 2, the system display screen 3, the system power key 4, the current adjusting knob 5 and the control key are all connected with the processing unit, and the stimulation electrode jack 2 is provided with a positive electrode and a negative electrode;
the processing unit comprises a microprocessor MCU with an A/D conversion module, the microprocessor MCU is connected with an operation module and a liquid crystal display module, the microprocessor MCU is connected with a battery capacity detection module, an impedance detection module and a current detection module through the A/D conversion module, the battery capacity detection module is connected with a power supply module, the power supply module is connected with a boosting module, the boosting module is connected with a constant current source module, the constant current source module is connected with the current detection module and a stimulation module, the stimulation module is connected with the impedance detection module, the current detection module is connected with the microprocessor MCU through an overcurrent protection and alarm module, the overcurrent protection and alarm module is used for cutting off the connection between a power supply and the constant current source and a stimulation electrode when the stimulation current exceeds the allowed maximum current, and alarming of sound and light is carried out, and the microprocessor MCU is connected with an upper computer through a Bluetooth module;
the constant current source module is connected with the negative electrode of the stimulating electrode jack 2, the boosting module is connected with the positive electrode of the stimulating electrode jack 2, the operation module is connected with the control key and the current adjusting knob 5, and the liquid crystal display module is connected with the system display screen 3;
the constant current source module consists of a controllable precise voltage-stabilizing source and an MOSFET (metal-oxide-semiconductor field effect transistor), is used for outputting direct current stimulation with constant intensity, and the stimulation current intensity is continuously adjustable within an allowable range;
the impedance detection module is used for measuring the impedance of the stimulated brain area;
the current detection module is connected with the overcurrent protection and alarm module through the comparator on one hand, and is connected with an A/D module in the MCU on the other hand, so that the setting of the stimulation current intensity before stimulation can be guided, and the stimulation current in the stimulation process can be monitored.
The overcurrent protection and alarm module is connected with the current detection module through the comparator on one hand, and is connected with an I/O port of the microprocessor MCU on the other hand, when the stimulation current exceeds the allowed maximum current, the connection of a power supply, a constant current source and a stimulation electrode can be quickly cut off, double protection is provided, and sound and light alarm is carried out.
Referring to fig. 3, the boost module includes a DC-DC conversion chip, pin 1 of the DC-DC conversion chip is connected to the positive electrode of the high-speed switching diode D and one end of the inductor L, pin 2 is grounded, pin 3 is grounded through the first capacitor CT, pin 4 is grounded, pin 5 is connected to one end of the first resistor R1 and one end of the second resistor R2, pin 6 is connected to one end of the third resistor RSC, the positive electrode of the third capacitor C1 and the positive electrode Vin of the battery, pin 7 is connected to the other end of the third resistor RSC, the other end of the inductor L and the first end of the fourth resistor R, pin 8 is connected to the other end of the fourth resistor R, the negative electrode of the high-speed switching diode D is connected to the other end of the second resistor R2, the positive electrode of the second capacitor C0 and the boosted output voltage Vout, and the other end of the second resistor R1 is connected to the negative electrode of the second capacitor C0 and the negative electrode of the third capacitor C1 and grounded.
The boosting module boosts the voltage output by the power supply module to a required size by using a DC-DC conversion chip to provide support for stimulation of current output by the constant current source module; the boost chip adopts a common DC-DC conversion chip, and in view of low conversion efficiency and large power consumption of a common boost circuit, the parameters of the boost circuit are optimized, and the conversion efficiency is effectively improved, the power consumption is reduced, the working time of a battery is prolonged, and the requirement of longer transcranial direct current stimulation can be met by changing the sizes of the resistor RSC, the inductor L and the capacitor CT
Preferably, the power supply module adopts a square 9V nickel-hydrogen rechargeable battery to supply power for other modules, the microprocessor MCU adopts an MSP430 series single chip microcomputer, an internal A/D module is directly connected with the current detection module, the impedance detection module and the battery power detection module, in addition, the overcurrent protection and alarm module, the liquid crystal display module and the operation module are directly connected with an I/O port of the microprocessor MCU, and the control key comprises a determination key 6, an upper selection key 7 and a lower selection key 8.
The liquid crystal display module can prompt whether the stimulation electrode is tightly contacted with the scalp or not, and can display the intensity of stimulation current, the impedance of the stimulation brain area, the stimulation time and the residual battery capacity.
The upper computer is based on software for monitoring transcranial direct current stimulation and can display the recorded stimulation current intensity and the stimulation brain area impedance curve in real time; the stimulation information of any previous time point can be inquired, and the stimulation information can be stored.
Referring to fig. 4 and 5, a method of operating a transcranial direct current stimulation device includes the steps of:
step one, pressing a power key, starting a system, initializing a microprocessor MCU, and initializing a peripheral chip;
inserting a lead connected with a stimulation electrode into an electrode jack of the device, and selecting a stimulation part;
step three, attaching the stimulation electrode to a stimulation part selected by the scalp, detecting whether the stimulation electrode is tightly contacted with the scalp by the impedance detection module, if so, carrying out the next step, otherwise, prompting on a system display screen 3, and carrying out peripheral chip initialization again;
step four, setting the stimulation current intensity, setting the stimulation time and starting a confirming key;
fifthly, the system starts to stimulate, data are acquired through the impedance detection module and the current detection module and displayed on a system display screen 3, and the data are transmitted to an upper computer through Bluetooth;
step six, the current detection module judges whether the current exceeds the maximum value, if not, stimulation is continued, if yes, an alarm is given, and stimulation is stopped;
and step seven, judging whether the stimulation time is finished or not by the microprocessor MCU, if not, continuing the stimulation, and if so, stopping the stimulation.
Claims (4)
1. A transcranial direct current stimulation device is characterized in that two stimulation electrodes are attached to different areas of a skull, and constant and low-intensity direct current of 1-2 mA is transmitted to specific areas of the skull, so that the excitability of cerebral cortical neurons is improved or reduced, and further the brain functionality is changed, and the transcranial direct current stimulation device is used for clinical treatment research of diseases such as Alzheimer's disease, Parkinson's disease and cognitive disorder; the device comprises a processing unit arranged in a shell (1), wherein a stimulation electrode jack (2), a system display screen (3), a system power key (4), a current adjusting knob (5) and a control key are arranged on the shell (1), the stimulation electrode jack (2), the system display screen (3), the system power key (4), the current adjusting knob (5) and the control key are all connected with the processing unit, and the stimulation electrode jack (2) is provided with a positive electrode and a negative electrode;
the method is characterized in that:
the processing unit comprises a microprocessor MCU with an A/D conversion module, the microprocessor MCU is connected with an operation module and a liquid crystal display module, the microprocessor MCU is connected with a battery electric quantity detection module, an impedance detection module and a current detection module through the A/D conversion module, the battery electric quantity detection module is connected with a power supply module, the power supply module is connected with a boosting module, the boosting module is connected with a constant current source module, the constant current source module is connected with the current detection module and a stimulation module, and the stimulation module is connected with the impedance detection module;
the constant current source module is connected with the negative electrode of the stimulating electrode jack (2), the boosting module is connected with the positive electrode of the stimulating electrode jack (2), the operation module is connected with the control key and the current adjusting knob (5), and the liquid crystal display module is connected with the system display screen (3);
the constant current source module consists of a controllable precise voltage-stabilizing source and an MOSFET (metal-oxide-semiconductor field effect transistor), is used for outputting direct current stimulation with constant intensity, and has continuously adjustable stimulation current intensity within an allowable range;
the impedance detection module is used for measuring the impedance for stimulating the brain region;
the current detection module is used for guiding the setting of the intensity of the stimulation current before stimulation and monitoring the magnitude of the stimulation current in the stimulation process; the current intensity flowing through the stimulating electrodes and the impedance between the stimulating electrodes are converted into corresponding analog voltage signals through a current detection module and an impedance detection module, the analog voltage signals are converted into digital signals through an A/D module in a microprocessor MCU, and corresponding current values and impedance values are calculated; when the stimulation current exceeds the allowed maximum value, on one hand, the analog voltage converted by the current detection module is compared with the preset voltage by the comparator, the power supply is quickly cut off, and meanwhile, the I/O port of the microprocessor MCU sends a signal to cut off the connection between the constant current source and the stimulation electrode, so that double protection is achieved, and sound and light alarm is carried out; if the calculated impedance value is far larger than the normal value, the stimulation electrode is determined not to be tightly contacted with the scalp, and the liquid crystal display screen can prompt; the calculated current value and the calculated impedance value are displayed on a system display screen in real time on one hand, and are transmitted to an upper computer through a Bluetooth module to be stored on the other hand;
the upper computer is based on software for monitoring transcranial direct current stimulation and can display the recorded stimulation current intensity and the stimulation brain area impedance curve in real time; the stimulation information of any previous time point can be inquired as well as the current intensity sent by the Bluetooth module, the polarity of the electrode, the brain stimulation part and the impedance information of the brain stimulation area during each stimulation;
in addition, the overcurrent protection and alarm module, the liquid crystal display module and the operation module are directly connected with an I/O port of the microprocessor MCU;
the current detection module is connected with the current detection module through the comparator on one hand, and is connected with an I/O port of the microprocessor MCU on the other hand, when the stimulation current exceeds the allowed maximum current, the connection of a power supply and a constant current source with a stimulation electrode can be quickly cut off, double protection is provided, and sound and light alarm is performed;
the boosting module boosts the voltage output by the power supply module to a required size by using a DC-DC conversion chip, and provides support for stimulation of current output by the constant current source module; the conversion efficiency is effectively improved, the power consumption is reduced, the working time of the battery is prolonged, and the transcranial direct current stimulation for a longer time can be met; the boosting module comprises a DC-DC conversion chip, wherein a pin 1 of the DC-DC conversion chip is connected with the anode of a high-speed switch diode D and one end of an inductor L, a pin 2 is grounded, a pin 3 is grounded through a first capacitor CT, a pin 4 is grounded, a pin 5 is connected with one ends of a first resistor R1 and a second resistor R2, a pin 6 is connected with one end of a third resistor RSC, the anode of a third capacitor C1 and the anode Vin of a battery, a pin 7 is connected with the other end of the third resistor RSC, the other end of the inductor L and the first end of a fourth resistor R, a pin 8 is connected with the other end of the fourth resistor R, the cathode of the high-speed switch diode D is connected with the other end of the second resistor R2, the anode of a second capacitor C0 and a boosted output voltage Vout, the other end of the second resistor R1 is connected with the cathode of the second capacitor C0 and the cathode of the third capacitor C1 and grounded, the conversion efficiency is increased by changing the sizes of the resistor RSC, the inductor L and the first capacitor CT.
2. The transcranial direct current stimulation device according to claim 1, characterized in that the control keys preferably comprise a determination key (6), an upper selection key (7) and a lower selection key (8).
3. A method of operating a transcranial direct current stimulation device according to claim 1 or claim 2, comprising the steps of:
step one, pressing a power key (4), starting a system, initializing a microprocessor MCU, and initializing a peripheral chip;
inserting a lead connected with a stimulation electrode into an electrode jack of the device, and selecting a stimulation part;
step three, attaching the stimulation electrode to the selected scalp stimulation part, detecting whether the stimulation electrode is tightly contacted with the scalp by the impedance detection module, if so, carrying out the next step, otherwise, prompting on a system display screen (3), and carrying out peripheral chip initialization again;
step four, setting the stimulation current intensity, setting the stimulation time and starting a confirming key (6);
fifthly, the system starts to stimulate, and data acquisition is carried out through an impedance detection module and a current detection module and is displayed on a system display screen (3);
step six, the current detection module judges whether the current exceeds the maximum value, if not, stimulation is continued, if yes, an alarm is given, and stimulation is stopped;
and step seven, judging whether the stimulation time is finished or not by the microprocessor MCU, if not, continuing the stimulation, and if so, stopping the stimulation.
4. The working method of claim 3, wherein the data in the fifth step is transmitted to an upper computer through Bluetooth.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110675185.6A CN113476741A (en) | 2016-11-16 | 2016-11-16 | Transcranial direct current stimulation device and working method |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611024708.6A CN106581854A (en) | 2016-11-16 | 2016-11-16 | Transcranial direct current stimulation device and work method thereof |
| CN202110675185.6A CN113476741A (en) | 2016-11-16 | 2016-11-16 | Transcranial direct current stimulation device and working method |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611024708.6A Division CN106581854A (en) | 2016-11-16 | 2016-11-16 | Transcranial direct current stimulation device and work method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113476741A true CN113476741A (en) | 2021-10-08 |
Family
ID=58591455
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110675185.6A Pending CN113476741A (en) | 2016-11-16 | 2016-11-16 | Transcranial direct current stimulation device and working method |
| CN201611024708.6A Pending CN106581854A (en) | 2016-11-16 | 2016-11-16 | Transcranial direct current stimulation device and work method thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611024708.6A Pending CN106581854A (en) | 2016-11-16 | 2016-11-16 | Transcranial direct current stimulation device and work method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (2) | CN113476741A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116617577A (en) * | 2023-06-05 | 2023-08-22 | 浙江大学 | Tumor electric field treatment method and system capable of achieving closed-loop regulation and control |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106861040A (en) * | 2017-02-16 | 2017-06-20 | 中国人民解放军第四军医大学 | A kind of brain damage reparation and the method and apparatus of reconstruction |
| CN108310639A (en) * | 2018-03-07 | 2018-07-24 | 北京大智商医疗器械有限公司 | Difference frequency electrical stimulation apparatus, system and method |
| CN108525124A (en) * | 2018-04-13 | 2018-09-14 | 隆林玲 | Through cranium galvanic current stimulation equipment |
| CN108671389A (en) * | 2018-04-25 | 2018-10-19 | 中国人民解放军军事科学院军事医学研究院 | Multi-mode is wearable through cranium electric current stimulating apparatus |
| CN108744273B (en) * | 2018-05-29 | 2020-04-28 | 西安交通大学 | Transcranial noninvasive deep brain bifocal stimulation system and method for neural circuit |
| CN108904975A (en) * | 2018-06-04 | 2018-11-30 | 江西京新医疗科技有限公司 | A kind of electrical transcranial stimulation middle impedance detection system |
| CN109011145A (en) * | 2018-08-10 | 2018-12-18 | 复旦大学 | A kind of Multifunctional ear Vagus nerve stimulation instrument |
| CN109045435A (en) * | 2018-09-03 | 2018-12-21 | 亮眼科技股份有限公司 | Visual training ancillary equipment |
| CN109200461B (en) * | 2018-10-29 | 2024-04-19 | 上海体育学院 | Transcranial direct current stimulation tights for enhancing exercise capacity |
| CN109621156A (en) * | 2019-01-04 | 2019-04-16 | 广东工业大学 | A kind of brain electricity reaction type microcurrent stimulating sleep assistance instrument and application method |
| CN109745617A (en) * | 2019-03-06 | 2019-05-14 | 浙江大学 | It is a kind of with reference electrode through cranium direct current stimulator and application method |
| CN110354382B (en) * | 2019-07-30 | 2023-11-14 | 军事科学院系统工程研究院军需工程技术研究所 | Helmet integrated transcranial electric stimulation device |
| CN111184308A (en) * | 2020-03-06 | 2020-05-22 | 沈富琴 | Cap with health care function |
| CN112891734B (en) * | 2021-01-26 | 2024-03-15 | 南京沃高医疗科技有限公司 | High-precision transcranial electric stimulation device |
| CN115068823B (en) * | 2022-08-19 | 2022-11-15 | 江西华恒京兴医疗科技有限公司 | Individualized transcranial direct current stimulation current intensity threshold detection system |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201282418Y (en) * | 2008-10-31 | 2009-07-29 | 上海大亚信息产业有限公司 | DC transfer switch power supply circuit structure for set-top box |
| CN102580235A (en) * | 2012-02-24 | 2012-07-18 | 江苏苏云医疗器材有限公司 | Transcranial direct current stimulation instrument |
| EP2978488B1 (en) * | 2013-03-29 | 2021-04-14 | GSK Consumer Healthcare S.A. | Detecting cutaneous electrode peeling using electrode-skin impedance |
| CN105983178B (en) * | 2015-02-02 | 2019-03-08 | 深圳市科曼医疗设备有限公司 | Pacemaking generation device |
| CN105664357A (en) * | 2016-01-04 | 2016-06-15 | 天津大学 | Multi-parameter adjustable transcranial current stimulation system |
-
2016
- 2016-11-16 CN CN202110675185.6A patent/CN113476741A/en active Pending
- 2016-11-16 CN CN201611024708.6A patent/CN106581854A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116617577A (en) * | 2023-06-05 | 2023-08-22 | 浙江大学 | Tumor electric field treatment method and system capable of achieving closed-loop regulation and control |
| CN116617577B (en) * | 2023-06-05 | 2024-03-26 | 浙江大学 | Tumor electric field treatment system capable of closed-loop regulation and control |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106581854A (en) | 2017-04-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN113476741A (en) | Transcranial direct current stimulation device and working method | |
| US20120109251A1 (en) | Transcranial electrostimulation device | |
| CN102613971B (en) | Electroencephalograph (EEG)-based epilepsy detection and intervention device | |
| US20070032827A1 (en) | Method and apparatus for producing therapeutic and diagnostic stimulation | |
| CN108525124A (en) | Through cranium galvanic current stimulation equipment | |
| KR102594062B1 (en) | Device for the transcutaneous electrical stimulation of the trigeminal nerve | |
| WO2007108718A1 (en) | Transcranial electrostimulation device | |
| CN107684664A (en) | A kind of Intelligent Composite waveform electrical transcranial stimulation system | |
| WO2011097210A1 (en) | Electrical brain stimulation in the gamma band | |
| CN2891967Y (en) | Driver's fatigue driving monitoring and feedback stimulating instrument | |
| WO2002022203A1 (en) | Electrical stimulation of tissue for therapeutic and diagnostic purposes | |
| CN109173042B (en) | Vagus nerve stimulation device for weight reduction | |
| CN104874102A (en) | Multi-channel wireless closed loop deep brain neural sensing and control system | |
| CN105664357A (en) | Multi-parameter adjustable transcranial current stimulation system | |
| CN109621156A (en) | A kind of brain electricity reaction type microcurrent stimulating sleep assistance instrument and application method | |
| CN112827066A (en) | Multifunctional transcranial stimulation magnetic therapy device | |
| CN108578891A (en) | A kind of hardware circuit of pain electric pulse therapeutic equipment | |
| CN103816613A (en) | Portable electrical stimulator for tibialis anterior muscle | |
| CN218589019U (en) | Electroencephalogram acquisition and transcranial electrical stimulation integrated nerve regulation and control equipment | |
| CN111013015A (en) | Self-feedback physiotherapy instrument | |
| CN208641548U (en) | Biofeedback type headache therapeutic equipment | |
| CN107007933B (en) | Pace-making generating device | |
| CN112023262A (en) | Bipolar pulse human brain epilepsy threshold stimulator based on STM32 single chip microcomputer | |
| CN210096687U (en) | Transcranial direct current stimulator with reference electrode | |
| CN219614735U (en) | B-type transcranial direct current stimulator |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |