CN105983178B - Pacemaking generation device - Google Patents
Pacemaking generation device Download PDFInfo
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- CN105983178B CN105983178B CN201510054434.4A CN201510054434A CN105983178B CN 105983178 B CN105983178 B CN 105983178B CN 201510054434 A CN201510054434 A CN 201510054434A CN 105983178 B CN105983178 B CN 105983178B
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Abstract
The present invention relates to a kind of pacemaking generation devices, comprising: impedance detection unit, for detecting impedance value and the output of patient；Constant-current source, for being connect with patient and exporting pacemaker current to patient；Microprocessor is used to export analog voltage to constant-current source according to target pacemaker current signal, to control constant-current source output pacemaker current；Microprocessor is also used to receive impedance value, and determines output regulation signal after target voltage values according to impedance value and target pacemaker current signal；And boosting unit, for receiving adjustment signal and adjusting pace-making vector according to adjustment signal；Boosting unit, which is also used to connect with patient to patient, exports pace-making vector.Above-mentioned pacemaking generation device can effectively ensure that the electric current being loaded into patient and voltage security, to ensure that the safety of patient.
Description
Technical field
The present invention relates to the field of medical instrument technology, more particularly to pacemaking generation device.
Background technique
Need to carry out patient external noninvasive pace-making in clinical emergency aid and treatment occasion to obtain timely rescued effect.It removes
The patient monitor that quivers has noninvasive pacing function, can generate the electric pulse of some strength and width, and be released to heart by electrode,
Stimulation cardiac muscle, so as to be treated to the bradycardia after defibrillation.The external human body chest resistance more internal impedance of range is wide, and one
As variation range from 20 ohm~200 ohm.In view of the difference of various human bodies and the contact impedance of skin, defibrillation monitor
The impedance ranges that pace of setting are generally 20 ohm~750 ohm, and clinical effective stimulus pulse current variation range 5mA~
200mA.Therefore the voltage range for acting on human body is 0.1V~150V.Since electric pulse directly acts on human body cardiac stimulus,
Excessively high voltage and excessive electric current will damage patient, therefore need to be during pace-making to the pace-making for acting on human body
Voltage and current is monitored in real time, is stopped pace-making output when overtension or excessive electric current occurs, is protected patient.
To the voltage protection of pacing circuitry by the way of hardware protection, protection point basic settings is traditional pacing system
The maximum operating voltage of beating device.And when the impedance of patient is lower, since pace-making protects point voltage setting excessively high, it is loaded into people
After body, patient can still be damaged.The current control of traditional pacing system is to be carried out by sampling resistor to pacemaker current
It samples, is sent into microprocessor carries out judging whether electric current is normal after ADC digital, if current anomaly, cut off pace-making circuit；
This method uses software realization.And (1) software sampling is had the disadvantage that current control using software mode, there is certain prolong
Shi Xing；(2) when software sampling malfunctions, excessively high pacemaker current can be caused harm to the human body.
Summary of the invention
Based on this, it is necessary in view of the above-mentioned problems, the pace-making for providing a kind of safety that can effectively ensure that patient fills
It sets.
A kind of pacemaking generation device, comprising: impedance detection unit, for detecting impedance value and the output of patient；Constant-current source,
For being connect with patient and exporting pacemaker current to the patient；Microprocessor, respectively with the impedance detection unit, the perseverance
The connection of stream source；The microprocessor is used to export analog voltage according to target pacemaker current signal to the constant-current source, to control
Make the constant-current source output pacemaker current；The microprocessor is also used to receive the impedance value, and according to the impedance value and
The target pacemaker current signal determines output regulation signal after target voltage values；And boosting unit, with the microprocessor
Connection, for receiving the adjustment signal and adjusting pace-making vector according to the adjustment signal；The boosting unit be also used to
Patient connects to the patient and exports pace-making vector.
It in one of the embodiments, further include Overvoltage protecting unit；The Overvoltage protecting unit is connected to the boosting
Between unit and the microprocessor；The pace-making vector that the Overvoltage protecting unit is used to export the boosting unit is adopted
Sample and sampled voltage there are output overvoltage signal when over-voltage give the boosting unit and the microprocessor；The overvoltage protection
Unit includes first order overvoltage crowbar and second level overvoltage crowbar；The first order overvoltage crowbar is used for institute
It states compared with sampled voltage protects voltage signal with the first order and is greater than the first order in the sampled voltage and protect voltage signal
When output overvoltage signal；The second level overvoltage crowbar is used to the sampled voltage and the second level protecting voltage signal ratio
Output overvoltage signal when being greater than second level protection voltage signal compared with and the sampled voltage；The first order protects voltage
Signal is less than the second level and protects voltage signal.
The first order protection voltage signal is adjustable voltage signal in one of the embodiments, by the micro process
Device is set according to the target voltage values；The second level protection voltage signal is fixed voltage signal, according to described
Fight generating device maximum operating voltage determine.
The first order overvoltage crowbar includes first comparator, first resistor and in one of the embodiments,
One diode；The input terminal of the first comparator is respectively sampling voltage input and first order protection voltage signal input
End；The output end of the first comparator is connect with the first resistor, the first diode respectively；The first resistor is also
It is connect with power input；The cathode of the first diode is also connect with the microprocessor, the boosting unit；Described
Second level overvoltage crowbar includes the second comparator, second resistance, 3rd resistor, the 4th resistance and the second diode；It is described
The input terminal of second comparator is respectively sampling voltage input and second level protection voltage signal inputs；The second level is protected
Shield voltage signal is divided and is formed by the second resistance and the 3rd resistor；The output end of second comparator respectively with institute
State the 4th resistance, the connection of the second diode；4th resistance is also connect with the power input；Second diode
Cathode is also connect with the cathode of the first diode.
It in one of the embodiments, further include over-current protecting unit and current sampling unit；The current sampling unit
It is connect with the constant-current source, the pacemaker current for exporting to the constant-current source is sampled and exports sample rate current；The mistake
Stream protection location is connect with the current sampling unit, the constant-current source and the microprocessor respectively；The overcurrent protection
Unit includes first order current foldback circuit and second level current foldback circuit；The first order current foldback circuit is used for institute
Sample rate current is stated compared with first order protective current signal and is greater than the first order protective current signal in the sample rate current
When output overcurrent signal；The second level current foldback circuit is used for the sample rate current and second level protective current signal ratio
Output overcurrent signal when being greater than the second level protective current signal compared with and the sample rate current；The first order protective current
Signal is less than the second level protective current signal.
The first order protective current signal is adjustable current signal in one of the embodiments, by the micro process
Device is set according to the target pacemaker current signal；The second level protective current signal is fixed current signal, according to
The maximum operating currenbt of the pacemaking generation device determines.
The first order current foldback circuit includes third comparator, the 5th resistance, third in one of the embodiments,
Diode；The input terminal of the third comparator is respectively sample rate current input terminal and first order protective current signal input part；
The output end of the third comparator is connect with the 5th resistance, the third diode respectively；5th resistance also with
Power input connection；The cathode of the third diode is also connect with microprocessor, the constant-current source；The second level overcurrent
Protecting circuit includes the 4th comparator, the 6th resistance, the 7th resistance, the 8th resistance and the 4th diode；Described 4th compares
The input terminal of device is respectively sample rate current input terminal and second level protective current signal input part；Second level protective current signal is defeated
Enter end to be connected between the 6th resistance and the 7th resistance；6th resistance is also connect with power input, described
The other end of 7th resistance is grounded；The output end of 4th comparator also respectively with the 8th resistance, the four or two pole
Pipe connection；8th resistance is also connect with the power input；The cathode of 4th diode is also with the described 3rd 2
The cathode of pole pipe connects.
The first order current foldback circuit further includes the first latching circuit in one of the embodiments,；Described first
Latching circuit is connected to the output end and sample rate current input terminal of the third comparator；The second level current foldback circuit is also
Including the second latching circuit；Second latching circuit is connected to output end and the sample rate current input of the 4th comparator
End.
The over-current protecting unit further includes overcurrent reset circuit in one of the embodiments,；The overcurrent resets electricity
Road includes the first triode and the 9th resistance；The base stage of first triode is connect with the microprocessor, for receiving
State the overcurrent reset signal of microprocessor output；The sampling with the third comparator respectively of the collector of first triode
The sample rate current input terminal connection of current input terminal, the 4th comparator；The emitter series connection the described 9th of first triode
It is grounded after resistance.
The current sampling unit includes that operational amplifier, the first sampled point and second are adopted in one of the embodiments,
Sampling point；First sampled point and second sampled point are located at the different location of the constant-current source；First sampling
Point, second sampled point are connect with the first input end of the operational amplifier, the second input terminal respectively；Second sampling
Point is also connect with the sample rate current input terminal of the third comparator；The output end of the operational amplifier is compared with the described 4th
The sample rate current input terminal of device connects.
Above-mentioned pacemaking generation device, electricity can be paced according to target by microprocessor by being applied to the pacemaker current with patient
Stream signal exports corresponding analog voltage to control constant-current source output target pacemaker current；Pace-making vector then can be by micro process
Device calculates the pace-making vector of suitable patient according to the impedance value and target pacemaker current signal of patient, so that output is corresponding
Adjustment signal is adjusted the pace-making vector being applied to patient, can effectively ensure that the electric current being loaded into patient with
And voltage security, to ensure that the safety of patient.
Detailed description of the invention
Fig. 1 is the structural block diagram of the pacemaking generation device in an embodiment；
Fig. 2 is the structural block diagram of the pacemaking generation device in another embodiment；
Fig. 3 is the circuit diagram of the constant-current source and current sampling unit in pacemaking generation device shown in Fig. 2；
Fig. 4 is the circuit diagram of the over-current protecting unit in pacemaking generation device shown in Fig. 2；
Fig. 5 is the circuit diagram of the Overvoltage protecting unit in pacemaking generation device shown in Fig. 2.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to the accompanying drawings and embodiments, right
The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and
It is not used in the restriction present invention.
Fig. 1 is the structural block diagram of the pacemaking generation device in an embodiment.A kind of pacemaking generation device, including impedance detection
Unit 110, constant-current source 120, microprocessor 130 and boosting unit 140.Wherein, impedance detection unit 110 and microprocessor
130 connections, microprocessor 130 are also connect with boosting unit 140 and constant-current source 120 respectively.
Impedance detection unit 110 is connect by electrode with patient, thus the impedance value of patient is detected and export to
Microprocessor 130.Constant-current source 120 is also connect by electrode with patient, for exporting pacemaker current to patient.Microprocessor 130
Answer simulation voltage to constant-current source for receiving target pacemaker current signal, and according to the target pacemaker current signal output phase
120, so that controlling constant-current source 120 exports corresponding pacemaker current, it is ensured that the electric current safety being loaded on patient body.Micro process
Device 130 is also used to receive the impedance value of the output of impedance detection unit 110, and according to the impedance value and target pacemaker current signal
Output regulation signal is to boosting unit 140 after determining target voltage values.Boosting unit 140 according to the adjustment signal received to rise
Voltage of fighting is adjusted, to export target pace-making vector to patient by electrode, it is ensured that the voltage being loaded on patient body
Safety.
Above-mentioned pacemaking generation device, be applied to pacemaker current with patient can by microprocessor 130 according to target
Current signal of fighting exports corresponding analog voltage and exports target pacemaker current to control constant-current source 120；Pace-making vector then can be with
The pace-making vector for calculating suitable patient according to the impedance value and target pacemaker current signal of patient by microprocessor 130, from
And export corresponding adjustment signal and the pace-making vector being applied to patient is adjusted, it can effectively ensure that and be loaded into patient
Electric current and voltage security with it, to ensure that the safety of patient.
Fig. 2 is the structural block diagram of the pacemaking generation device in another embodiment.A kind of pacemaking generation device includes impedance inspection
Survey unit 210, constant-current source 220, current sampling unit 230, microprocessor 240, over-current protecting unit 250, boosting unit 260 with
And Overvoltage protecting unit 270.
Impedance detection unit 210 is connect by electrode with patient, and is detected to the impedance value of patient.Specifically, it hinders
The current value and voltage value that anti-detection unit 210 can detect the voltage and current for flowing through patient and be obtained according to detection
The impedance value of patient is calculated.
Constant-current source 220 is connect with microprocessor 240, current sampling unit 230 and over-current protecting unit 250 respectively.It is micro-
For receiving target pacemaker current signal, target pacemaker current signal can carry out processor 240 according to the concrete condition of patient
Setting.Needed for microprocessor 240 calculates the generation target pacemaker current of constant-current source 220 according to the target pacemaker current signal received
The voltage value wanted.Microprocessor 240 is according to voltage value control DAC (digital analog converter) the output analog voltage being calculated
DAC_CURRENT is to constant-current source 220.Constant-current source 220 is under the control of analog voltage DAC_CURRENT to the pacemaker current of output
It is adjusted, to achieve the purpose that adjust body current.Current sampling unit 230 respectively with constant-current source 220, microprocessor
240 and over-current protecting unit 250 connect.Current sampling unit 230 is used to carry out the pacemaker current in 220 circuit of constant-current source
Sampling, and sample rate current is exported to over-current protecting unit 250.In the present embodiment, current sampling unit 230 can also pass through mould
Output is to microprocessor 240 after sample rate current is converted to digital current signal by number converter.
Fig. 3 is the circuit diagram of constant-current source 220 and current sampling unit 230.Constant-current source 220 includes operational amplifier
U5, diode Q2, metal-oxide-semiconductor Q3 and resistance R10~R13.Wherein, the first input end series resistance R10 of operational amplifier U5
It is connect afterwards with microprocessor 240, for receiving the analog voltage DAC_CURRENT of the output of microprocessor 240.Operational amplifier U5
Output end series resistance R13 after be connected to the grid of metal-oxide-semiconductor Q3.The grid of metal-oxide-semiconductor Q3 is also attached to the current collection of triode Q2
Pole.The base stage of triode Q2 is connect with over-current protecting unit 270, for receiving the over-current signal of its output.The hair of triode Q2
Emitter grounding.It is grounded after the drain series resistance R11 and resistance R12 of metal-oxide-semiconductor Q3.The source electrode of metal-oxide-semiconductor Q3 passes through electrode and patient
Connection.Current sampling unit 230 includes operational amplifier U6, the first sampled point P1 and the second sampled point P2.First sampled point P1
The different location in constant-current source 220, shadow when so as to avoid circuit from single failure occur are located at the second sampled point P2
Ring the normal work of current sample.Specifically, the second sampled point P2 is set to the drain electrode of metal-oxide-semiconductor Q2, and the first sampled point P1 is then set
It is placed between resistance R11 and resistance R12.First sampled point P1 and the second sampled point P2 are defeated with the first of operational amplifier U6 respectively
Enter end to connect with the second input terminal.First sampled point P1 is also used as the first current sampling signal output end and over-current protecting unit
Sample rate current input terminal connection in first order current foldback circuit in 250.The output end of operational amplifier U6 then with overcurrent
Sample rate current input terminal connection in second level current foldback circuit in protection location 250.
Whether over-current protecting unit 250 is for depositing pacemaker current according to the sample rate current that current sampling unit 230 exports
Real-time monitoring is carried out in overcurrent condition, output overcurrent signal controls constant-current source to constant-current source 220 if detecting overcurrent condition
Triode Q2 conducting in 220 quickly and effectively turns off the output of pacemaker current so that metal-oxide-semiconductor Q3 ends, it is ensured that applies
Electric current safety on a patient body.Meanwhile over-current protecting unit 250 can also export over-current signal to microprocessor 240.It is micro-
After processor 240 receives over-current signal, control DAC stopping exports analog voltage to constant-current source 220, so that constant-current source 220 stops
It only works, is further ensured that electric current safety.
In the present embodiment, over-current protecting unit 250 includes first order current foldback circuit, second level current foldback circuit
And overcurrent reset circuit, as shown in Figure 4.Wherein, first order current foldback circuit includes third comparator U3, third diode
D3, the 5th resistance R5 and the first latching circuit.The input terminal of third comparator U3 is respectively that first order protective current signal is defeated
Enter end and sample rate current input terminal.Wherein, first order protective current signal input part is connect with microprocessor 240, for receiving
The first order protective current signal DA_SAMPLE that microprocessor 240 exports.Sample rate current input terminal then with current sampling unit
The first sampled point P1 connection in 230, for receiving the first current sampling signal.In the present embodiment, first order protective current
Signal DA_SAMPLE is to be set by microprocessor 240 according to target pacemaker current signal, is adjustable current signal.
Since different patients can set different target pacemaker current signals, the setting of first order protective current signal can be with
It is adapted with the concrete condition of patient, so that it is guaranteed that applying electric current safety on a patient body.In the present embodiment, the first order
Protective current signal DA_SAMPLE is set as 1.1 times of target pacemaker current signal.The output end series connection the of third comparator U3
It is connect respectively with microprocessor 240 and constant-current source 220 after three diode D3.Third comparator U3 is greater than the first order in sample rate current
When protective current signal, meeting output overcurrent signal is to microprocessor 240 and constant-current source 220.In the present embodiment, over-current signal is
High level signal.First latching circuit includes diode D5.The anode of diode D5 is connected to the input terminal of third comparator U3,
Cathode is then connected to the sample rate current input terminal of third comparator U3.First latching circuit can be realized self-locking function, that is, serve as
Outflow is current, and latching circuit can feed back the output signal of third comparator U3 to input terminal, so that input terminal obtains
Constant input signal, to maintain the output of third comparator U3.And without the comparator of self-locking function, since sample rate current subtracts
When the small output switching for leading to third comparator U3, microprocessor break down and do not stop DAC output pacemaker current, pace-making electricity
Stream will continue on human body, damage to patient.
Second level current foldback circuit include the 4th comparator U4, the 6th resistance R6, the 7th resistance R7, the 8th resistance R8 with
And the 4th diode D4, it further include second from lock unit.The input terminal of 4th comparator U4 is respectively second level protective current letter
Number input terminal and sample rate current input terminal.Wherein, protective current signal in the second level is greater than first order protective current signal.The second level
Protective current signal is fixed current signal, is set according to the maximum operating currenbt of pacemaking generation device.In this implementation
In example, 1.2 times of the maximum operating currenbt of pacemaking generation device are arranged in second level protective current signal.Second level protective current letter
Number input terminal is connected between the 6th resistance R6 and the 7th resistance R7.6th resistance R6 is also connect with power input VCC, and the 7th
The other end of resistance R7 is grounded.The sample rate current input terminal then output end with the operational amplifier U6 in current sampling unit 230
Connection, for receiving the second current sampling signal of its output.The output end of 4th comparator U4 is connected after the 4th diode D4
It is connect with microprocessor 240 and constant-current source 220.After the 8th resistance R8 of also series connection of the output end of 4th comparator U4 with power supply
Input terminal VCC connection.4th comparator U4 output overcurrent signal when sample rate current is greater than second level protective current signal.Second
Latching circuit includes diode D6.The anode of diode D6 is connected to the output end of the 4th comparator U4, and cathode is connected to the 4th
The sample rate current input terminal of comparator, for stablizing the output of the 4th comparator.
In the present embodiment, current sampling unit 230 is also connect with microprocessor 240, for by sample rate current export to
Microprocessor 240.Overcurrent protection threshold value is set in microprocessor 240, the overcurrent protection threshold value and second level protective current are believed
It is number identical.Microprocessor 240 can be by internal timer timing receipt sample rate current, when the sample rate current detected is greater than
When overcurrent protection threshold value, control DAC stops output analog voltage, so that constant-current source 220 stops working.
Overcurrent reset circuit includes the first triode Q1, the 9th resistance R9 and diode D7, D8.Wherein, the one or three pole
The base stage of pipe Q1 is connect with microprocessor 240, for receiving the overcurrent reset signal of the output of microprocessor 240.First triode
The collector of Q1 is connect with the cathode of diode D7, diode D8 respectively.The anode of diode D7 is connected to third comparator U3
Sample rate current input terminal, the anode of diode D8 is then connected to the sample rate current input terminal of the 4th comparator U4.One or three pole
It is grounded after the 9th resistance R9 of emitter series connection of pipe Q1.In the present embodiment, self-locking due to being provided in current foldback circuit
Circuit, therefore the comparator stable output overcurrent signal always after overcurrent generation.After overcurrent releases, microprocessor 240
It can be to overcurrent reset circuit output overcurrent reset signal.Overcurrent reset signal is high level signal, so that the first triode Q3
Conducting, the level of the sample rate current input terminal of third comparator U3 and the 4th comparator U4 is dragged down, third comparator U3 and the
Four comparator U4 stop output overcurrent signal, realize the reset to comparator.
By the way that two-stage current protecting circuit is arranged, second level over-current protection point is higher than first order over-current protection point.Therefore exist
When overcurrent occurs, first order protection can be triggered first, if first order shielding failure, can also trigger second level overcurrent protection,
So as to which the electric current safety of load on a patient body is effectively ensured.Current protecting circuit can be realized self-locking function, once
Overcurrent occurs, by locking over-current signal output, turns off the output of pacemaker current.Also, microprocessor 240 can also be according to sampling
Electric current is monitored pacemaker current.Therefore, when over-current protecting unit 250 fails, additionally it is possible to be carried out by microprocessor 240
Overcurrent protection, to realize the three-level protective to overcurrent, it is ensured that be loaded into the electric current safety of human body.Due to microprocessor 240
Overcurrent protection has time delay, therefore its overcurrent protection is necessarily delayed in second level current foldback circuit.
Microprocessor 240 is also used to receive the impedance value of the output of impedance detection unit 210, and is risen according to impedance value and target
Current signal of fighting calculates the target voltage values for being suitable for patient.Microprocessor 240 is answered according to the target voltage values output phase of calculating
Adjustment signal to boosting unit 260.Boosting unit 260 is adjusted pace-making vector according to the adjustment signal, to reach
Change the purpose of the pace-making vector of output.Boosting unit 260 includes booster converter and digital regulation resistance.Digital regulation resistance connects
It is connected between the feedback end of booster converter and ground terminal.Connection of the digital regulation resistance also with microprocessor 240, for according to tune
Signal is saved to adjust resistance value, to realize the adjustment to pace-making vector.
Overvoltage protecting unit 270 is connected between boosting unit 260 and microprocessor 240.Overvoltage protecting unit 270 is used for
The pace-making vector exported to boosting unit 260 samples, and in sampled voltage, there are output overvoltage signals when over-voltage to give boosting list
Member 260, directly drags down the enable signal of booster converter, forbids booster converter enabled, quickly and effectively shutdown pace-making electricity
The output of pressure.Overvoltage protecting unit 270 can also export over-voltage signal to microprocessor 240.Microprocessor 240 was receiving
After pressing signal, exports and forbid enable signal to boosting unit, turn off the output of pace-making vector.
Overvoltage protecting unit 270 includes first order overvoltage crowbar and second level overvoltage crowbar, as shown in Figure 5.
First order overvoltage crowbar includes first comparator U1, first resistor R1 and first diode D1.Wherein, first comparator U1
Input terminal be that sampling voltage input and the first order protect voltage signal inputs.The first order protect voltage signal inputs with
Microprocessor 240 connects, and the first order for receiving the output of microprocessor 240 protects voltage signal DA.In the present embodiment,
First class of protection voltage signal DA is adjustable voltage signal, is determined by microprocessor 240 according to target pace-making vector value, thus
So that first order protection voltage signal DA matches with patient.In the present embodiment, first order protection voltage signal DA is set as
1.1 times of target pace-making vector.First comparator U1 output end series connection first diode D1 after respectively with microprocessor 240 with
And boosting unit 260 connects.The output end of first comparator U1 is also connected and is connect after first resistor R1 with power input VCC.
When sampled voltage is greater than first order protection voltage signal DA, first comparator U1 output overvoltage signal.
Second level overvoltage crowbar include the second comparator U2, second resistance R2,3rd resistor R3, the 4th resistance R4 and
Second diode D2.Wherein, the input terminal of the second comparator U2 is that sampling voltage input and the second level protect voltage signal defeated
Enter end.Second level protection voltage signal inputs are connected between second resistance R2 and 3rd resistor R3.Second resistance R2 also with
Power input connection, the other end ground connection of 3rd resistor R3.In the present embodiment, protection voltage signal in the second level is greater than first
Grade protection voltage signal DA.It is fixed voltage signal that voltage signal is protected in the second level, can be according to pacemaking generation device most
High working voltage is set.In the present embodiment, protection voltage signal in the second level is set as the most senior engineer of pacemaking generation device
1.15 times for making voltage.The output end of second comparator U2 connect after the second diode D2 respectively with microprocessor 240 and rise
Unit 260 is pressed to connect.The output end of second comparator U2 is also connected and is connect after the 4th resistance R4 with power input VCC.When adopting
When sample voltage is greater than second level protection voltage signal, the second comparator U2 output overvoltage signal.
Overvoltage protecting unit 270 has fully considered single failure situation by the way of twin-stage protection, so that in single event
Barrier situation remains to the output for effectively closing pace-making vector, improves the safety and reliability of system, can guarantee to be applied to trouble
Voltage security with person.And the first order protects voltage signal can be according to target voltage values (i.e. target pacemaker current signal
And patent impedance) carry out over-voltage protection point adjustment so that overvoltage protection can adapt to different patients.
Above-mentioned pacemaking generation device, apply pacemaker current on a patient body and pace-making vector can according to patient from
The impedance value of body is set, to avoid pace-making vector is excessively high, pacemaker current is excessive from damaging to patient.Also, it is above-mentioned
Pacemaking generation device is additionally provided with the over-current protecting unit 250 of twin-stage protection and the Overvoltage protecting unit 270 of twin-stage protection, can
Guarantee to apply voltage on a patient body and electric current safety.
Above-mentioned pacemaking generation device further includes DC-DC isolated location, for completing pace-making vector output loop and input source
Between isolation, play the purpose be isolated with network source of pace-making output loop.Boosting unit 260 is DC-DC boosting unit.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, all should be considered as described in this specification.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention
Range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.
Claims (9)
1. a kind of pacemaking generation device characterized by comprising
Impedance detection unit, for detecting impedance value and the output of patient；
Constant-current source, for being connect with patient and exporting pacemaker current to the patient；
Microprocessor is connect with the impedance detection unit, the constant-current source respectively；The microprocessor is used for according to being received
Target pacemaker current signal export analog voltage to the constant-current source, to control the constant-current source output pacemaker current；Institute
It states microprocessor and is also used to receive the impedance value, and target is determined according to the impedance value and the target pacemaker current signal
Output regulation signal after voltage value；And
Boosting unit is connect with the microprocessor, for receiving the adjustment signal and being adjusted according to the adjustment signal
It fights voltage；The boosting unit, which is also used to connect with patient to the patient, exports pace-making vector；
The pacemaking generation device further includes over-current protecting unit and current sampling unit；The current sampling unit and the perseverance
The connection of stream source, the pacemaker current for exporting to the constant-current source are sampled and export sample rate current；The overcurrent protection list
Member is connect with the current sampling unit, the constant-current source and the microprocessor respectively；The over-current protecting unit includes
First order current foldback circuit and second level current foldback circuit；
The first order current foldback circuit is used for the sample rate current compared with first order protective current signal and described
Output overcurrent signal when sample rate current is greater than the first order protective current signal；
The second level current foldback circuit is used for the sample rate current compared with the protective current signal of the second level and described
Output overcurrent signal when sample rate current is greater than the second level protective current signal；The first order protective current signal is less than institute
State second level protective current signal.
2. pacemaking generation device according to claim 1, which is characterized in that further include Overvoltage protecting unit；The over-voltage
Protection location is connected between the boosting unit and the microprocessor；The Overvoltage protecting unit is used for single to the boosting
The pace-making vector that member exports carries out sampling and there are output overvoltage signals when over-voltage to the boosting unit and institute in sampled voltage
State microprocessor；The Overvoltage protecting unit includes first order overvoltage crowbar and second level overvoltage crowbar；
Compared with the first order overvoltage crowbar is used to the sampled voltage protecting voltage signal with the first order and described
Output overvoltage signal when sampled voltage is greater than first order protection voltage signal；
Compared with the second level overvoltage crowbar is used to the sampled voltage protecting voltage signal with the second level and described
Output overvoltage signal when sampled voltage is greater than second level protection voltage signal；The first order protection voltage signal is less than institute
State second level protection voltage signal.
3. pacemaking generation device according to claim 2, which is characterized in that the first order protection voltage signal is adjustable
Voltage signal is set by the microprocessor according to the target voltage values；The second level protection voltage signal is solid
Determining voltage signal is determined according to the maximum operating voltage of the pacemaking generation device.
4. pacemaking generation device according to claim 2, which is characterized in that the first order overvoltage crowbar includes the
One comparator, first resistor and first diode；The input terminal of the first comparator is respectively sampling voltage input and
First class of protection voltage signal inputs；The output end of the first comparator respectively with the first resistor, the one or two pole
Pipe connection；The first resistor is also connect with power input；The cathode of the first diode also with the microprocessor, institute
State boosting unit connection；
The second level overvoltage crowbar includes the second comparator, second resistance, 3rd resistor, the 4th resistance and the two or two
Pole pipe；The input terminal of second comparator is respectively sampling voltage input and second level protection voltage signal inputs；Institute
Second level protection voltage signal is stated to be divided and formed by the second resistance and the 3rd resistor；The output of second comparator
End is connect with the 4th resistance, the second diode respectively；4th resistance is also connect with the power input；Described
The cathode of two diodes is also connect with the cathode of the first diode.
5. pacemaking generation device according to claim 1, which is characterized in that the first order protective current signal is adjustable
Current signal is set by the microprocessor according to the target pacemaker current signal；The second level protective current letter
Number be fixed current signal, according to the maximum operating currenbt of the pacemaking generation device determine.
6. pacemaking generation device according to claim 1, which is characterized in that the first order current foldback circuit includes the
Three comparators, the 5th resistance, third diode；The input terminal of the third comparator is respectively sample rate current input terminal and first
Grade protective current signal input part；The output end of the third comparator respectively with the 5th resistance, the third diode
Connection；5th resistance is also connect with power input；The cathode of the third diode also with microprocessor, the constant current
Source connection；
The second level current foldback circuit includes the 4th comparator, the 6th resistance, the 7th resistance, the 8th resistance and the four or two
Pole pipe；The input terminal of 4th comparator is respectively sample rate current input terminal and second level protective current signal input part；The
Second class protection current signal input is connected between the 6th resistance and the 7th resistance；6th resistance also with electricity
The connection of source input terminal, the other end ground connection of the 7th resistance；The output end of 4th comparator is also respectively with the described 8th
Resistance, the 4th diode connection；8th resistance is also connect with the power input；The yin of 4th diode
Pole is also connect with the cathode of the third diode.
7. pacemaking generation device according to claim 6, which is characterized in that the first order current foldback circuit further includes
First latching circuit；First latching circuit is connected to the output end and sample rate current input terminal of the third comparator；Institute
Stating second level current foldback circuit further includes the second latching circuit；Second latching circuit is connected to the 4th comparator
Output end and sample rate current input terminal.
8. pacemaking generation device according to claim 6, which is characterized in that the over-current protecting unit further includes that overcurrent is multiple
Position circuit；The overcurrent reset circuit includes the first triode and the 9th resistance；The base stage of first triode with it is described micro-
Processor connection, for receiving the overcurrent reset signal of the microprocessor output；The collector of first triode is distinguished
It is connect with the sample rate current input terminal of the sample rate current input terminal of the third comparator, the 4th comparator；One or three pole
It is grounded after emitter series connection the 9th resistance of pipe.
9. pacemaking generation device according to claim 6, which is characterized in that the current sampling unit includes operation amplifier
Device, the first sampled point and the second sampled point；First sampled point and second sampled point are located at the constant-current source
Different location；First sampled point, second sampled point respectively with the first input end of the operational amplifier, second defeated
Enter end connection；Second sampled point is also connect with the sample rate current input terminal of the third comparator；The operational amplifier
Output end connect with the sample rate current input terminal of the 4th comparator.
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| CN201510054434.4A CN105983178B (en) | 2015-02-02 | 2015-02-02 | Pacemaking generation device |
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| CN201510054434.4A CN105983178B (en) | 2015-02-02 | 2015-02-02 | Pacemaking generation device |
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| CN106581854A (en) * | 2016-11-16 | 2017-04-26 | 西安交通大学 | Transcranial direct current stimulation device and work method thereof |
| CN107007933B (en) * | 2017-03-06 | 2021-04-20 | 深圳市科曼医疗设备有限公司 | Pace-making generating device |
| CN106993369A (en) * | 2017-05-24 | 2017-07-28 | 南京工业大学 | Portable low-temp plasma producing apparatus with protecting human body function |
| CN109966644B (en) * | 2019-03-21 | 2023-05-12 | 百纳川医疗科技(苏州)有限公司 | Discharge protection circuit for defibrillator, defibrillator discharge system and defibrillator |
| CN110474622B (en) * | 2019-08-22 | 2023-08-15 | 海信空调有限公司 | Self-locking protection circuit and air conditioner |
| CN112054483B (en) * | 2020-08-04 | 2022-09-27 | 上海空间电源研究所 | Simple high-reliability overvoltage protection circuit |
| CN113791281B (en) * | 2021-08-24 | 2023-11-24 | 西安航天动力试验技术研究所 | Multichannel electric detonator control loop total resistance detection system |
| CN116488109A (en) * | 2022-01-17 | 2023-07-25 | 深圳市瑞沃德生命科技有限公司 | Protection circuit, biological sample preparation device and control method of protection circuit |
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| CN2756256Y (en) * | 2004-08-09 | 2006-02-08 | 陈钢 | Implanted type diaphragm pace-maker |
| CN101732795A (en) * | 2008-11-21 | 2010-06-16 | 深圳迈瑞生物医疗电子股份有限公司 | Pacemaking generation device and control method thereof |
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| CN103381284B (en) * | 2005-10-14 | 2017-03-01 | 内诺斯蒂姆股份有限公司 | Leadless cardiac pacemaker and system |
| CN201846067U (en) * | 2010-11-08 | 2011-05-25 | 四川九洲电器集团有限责任公司 | Circuit for real time monitoring and carefully protecting power supply |
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| CN2756256Y (en) * | 2004-08-09 | 2006-02-08 | 陈钢 | Implanted type diaphragm pace-maker |
| CN101732795A (en) * | 2008-11-21 | 2010-06-16 | 深圳迈瑞生物医疗电子股份有限公司 | Pacemaking generation device and control method thereof |
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