CN108671389A - Multi-mode is wearable through cranium electric current stimulating apparatus - Google Patents
Multi-mode is wearable through cranium electric current stimulating apparatus Download PDFInfo
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- CN108671389A CN108671389A CN201810381363.2A CN201810381363A CN108671389A CN 108671389 A CN108671389 A CN 108671389A CN 201810381363 A CN201810381363 A CN 201810381363A CN 108671389 A CN108671389 A CN 108671389A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/08—Arrangements or circuits for monitoring, protecting, controlling or indicating
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36025—External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
Abstract
It is wearable through cranium electric current stimulating apparatus that the invention discloses a kind of multi-modes, including：Hand-held control module, the corresponding stimulation parameter of stimulus modality and stimulus modality based on input and generate control instruction, wherein stimulus modality includes galvanic current stimulation pattern, impulse stimulation pattern, exchange electrical stimulation pattern and noise stimulus modality；Wearable module comprising stimulated current generation module and stimulated current output module, stimulated current generation module are decoded analysis to control instruction, and stimulated current output module is for exporting corresponding stimulated current signal；Bluetooth transceiver module comprising bluetooth sending module and bluetooth receiving module, bluetooth sending module are used to control instruction being sent to wearable module, and bluetooth receiving module is for receiving control instruction；Multiple electrodes；Electrode scalp impedance monitoring module and protection module.The multi-mode of the present invention is wearable can to realize a variety of output modes through cranium electric current stimulating apparatus, portable wearable and safe.
Description
Technical field
The invention belongs to through cranium electric current stimulating technology field, it is wearable through cranium electric current stimulating apparatus to be related to a kind of multi-mode.
Background technology
Electrical transcranial stimulation (transcranial electric current stimulation, tECS) is a kind of utilization
Weak current adjusts the excitatoty non-invasive cerebral nerve stimulating technology of Cortical Neurons, is produced by signal generating circuit
The current signal of the features such as raw Constant Direct Current, pulse, sine or random noise, cerebral nerve system is transmitted to by scalp electrode
System, influences the current potential of neuron and the excited threshold value of nerve fiber.Type electrical transcranial stimulation according to signal used is broadly divided into
Through cranium galvanic current stimulation (transcranial direct current stimulation, tDCS), through cranium electric-impulse stimulation
(transcranial pulse current stimulation, tPCS), through cranium exchange electro photoluminescence (transcranial
Direct current stimulation, tDCS) and through cranium noise stimulation (transcranial random noise
stimulation,tRNS)。
It is currently more common and easy to operation pass through the subthreshold value tune to nervous cell membrane potential through cranium galvanic current stimulation
Section, to the relevant cortical excitability of current direction and neuron activity for changing with flowing through targeted neuronal.It is pierced with through cranium magnetic
Swash and cause the synchronous discharge of a large amount of action potentials different, the threshold value of Neural spike train is stimulated in turn through the change of cranium galvanic current stimulation
Change the possibility that they are provided.And the means of brain are stimulated using non-constant current signal through cranium exchange stimulation etc., then it is logical
The concussion of interference brain is crossed to realize that nerve modulation is intended to.
That there is also structure functions is simple for the current device for electrical transcranial stimulation, stimulus modality is single, stimulation parameter
Adjustable extent is narrow, application flexibility is low, equipment is heavy and it is expensive the defects of, and with multi-functional, multi-mode, wearable, portable
The device through the stimulation of cranium electric current of the advantages that formula is very rare.In addition to this, safety is to need to examine through cranium electric current stimulating apparatus
Depending on major issue.In concrete application environment, such as encountering the electrode being in direct contact with scalp can not be bonded or electrode-head completely
Skin interface state changes electrode caused by (such as salt water sponge electrode loss of moist etc.)-scalp interface impedance variation, and then influences
The transmission and distribution of stimulated current.The increase of electrode-scalp interface impedance but will cause scalp and electrode contact position generate compared with
High contact voltage, to bring potential security risk to human body.
Being disclosed in the information of the background technology part, it is only intended to increase understanding of the overall background of the invention, without answering
It has been the prior art well known to persons skilled in the art when being considered as recognizing or imply that the information is constituted in any form.
Invention content
It is wearable through cranium electric current stimulating apparatus that the purpose of the present invention is to provide a kind of multi-modes, the structure work(to overcome
Energy is simple, stimulus modality is single, equipment is heavy and expensive disadvantage.
To achieve the above object, it is wearable through cranium electric current stimulating apparatus, the multi-mode that the present invention provides a kind of multi-modes
It is wearable to include through cranium electric current stimulating apparatus：Hand-held control module, the hand-held stimulus modality and thorn of the control module based on input
The corresponding stimulation parameter of energizing mode and generate control instruction, wherein stimulus modality includes galvanic current stimulation pattern, impulse stimulation mould
Formula, exchange electrical stimulation pattern and noise stimulus modality；Wearable module comprising stimulated current generation module and stimulated current are defeated
Go out module, stimulated current generation module is decoded analysis to control instruction, and the stimulus modality and stimulation required for user is joined
Number exports corresponding stimulated current signal by stimulated current output module；Bluetooth transceiver module, the bluetooth transceiver module include indigo plant
Tooth sending module and bluetooth receiving module, wherein bluetooth sending module is set in hand-held control module, is used for control instruction
It is sent to wearable module, bluetooth receiving module is set in wearable module, for receiving control instruction；Multiple electrodes, should
Electrode is bonded with scalp, for stimulated current signal to be transferred to skull and internal cerebral cortex；Electrode-scalp impedance monitoring mould
Block, impedance value of the electrode-between scalp impedance monitoring module monitors electrode and scalp, and impedance value is sent to described hold
Control module；And protection module, when impedance value is more than secure threshold, it is wearable through cranium electric current that protection module cuts off multi-mode
The power supply of stimulating apparatus.
In a preferred embodiment, multi-mode is wearable further includes through cranium electric current stimulating apparatus：Electric current stimulus mould
Block, electric current stimulation source module can be extended with multichannel output function；And electro photoluminescence selecting module, electro photoluminescence choosing
Module is selected for selecting in galvanic current stimulation pattern, impulse stimulation pattern, exchange electrical stimulation pattern and noise stimulus modality
One mode.
In a preferred embodiment, galvanic current stimulation pattern includes anode excitation mode, cathode stimulation mode and puppet
Stimulation mode.
In a preferred embodiment, in galvanic current stimulation pattern, output current signal opens latter section in stimulation
Gradually gradual change increases to stable state to output current in time, and gradually gradual change declines output current in stimulation end for the previous period
Zero is reduced to, fade time is adjustable in 1-120s, and adjusting step-length precision is 1s, output amplitude ranging from ± 5000 μ A, amplitude tune
Save 100 μ A of stepping, electric current maximum fluctuation<0.02%.
In a preferred embodiment, in impulse stimulation pattern, complete pulse cycle duration is in 300-
Adjustable in 2000ms, adjusting step-length is 100ms, and pulse period number is adjustable in 1-500, and current signal amplitude is in ± 5000uA
It is adjustable.
In a preferred embodiment, in exchanging electrical stimulation pattern, output current signal is sinusoidal signal, and amplitude exists
Adjustable in 0-5000uA, adjusting step-length is 25uA, and bias current is adjustable in 0- ± 1000uA, and adjusting step-length is 10uA, sinusoidal
Signal frequency is adjustable in 0-5KHz, wherein in 0-500Hz frequency ranges, adjusting step-length is 0.01Hz, in 500-5kHz frequency ranges,
Adjusting step-length is 10Hz, and phase is adjustable in 0-360 °, and phase adjusted step-length is 5 °.
In a preferred embodiment, in noise stimulus modality, noise signal is divided into lowpass noise and high pass noise
Output.
In a preferred embodiment, in noise stimulus modality, signal amplitude is adjustable in 0-1500uA, biased electrical
Adjustable in 0- ± 1000uA, stimulation time 0-60min is flowed, adjusts step-length 5s, the fade in/out time can in 0-120s
It adjusts.
In a preferred embodiment, hand-held control module further includes user interface, and user interface has
Button control section selects the corresponding circuit output pattern of stimulus modality, output current parameter and stimulation time, thorn by button
The sharp time is adjustable in 15s-60min, and adjusting stepping is 15s.
In a preferred embodiment, it through cranium electric current stimulating apparatus further includes power module, power supply that multi-mode is wearable
Module can generate the DC power supply of the amplitudes such as ± 30V and -5V, and DC power supply is capable of providing the output current of maximum 5mA, maximum
Output power is 0.15W, and output current serious forgiveness is less than 1%.
Compared with prior art, multi-mode according to the present invention is wearable has following beneficial effect through cranium electric current stimulating apparatus
Fruit：
(1) while having galvanic current stimulation pattern, impulse stimulation pattern, exchange electrical stimulation pattern and noise stimulus modality more
Kind output mode, the major parameters such as each mode output current amplitude, frequency of stimulation, stimulation time are adjustable in wide range, answer
With flexibility height；(2) demand that existing electrical transcranial stimulation technique generates hardware circuit signal is not only covered, but also is supported real-time
Monitoring returns simultaneously show electrode-scalp impedance, and early warning is carried out simultaneously certainly when impedance is more than secure threshold by setting threshold value of warning
Dynamic power-down procedure, substantially increases the security performance of device；(3) miniaturization of device, portability and wearable are realized；(4)
Multichannel output function can be formed by channel extension, can be applicable to the relevant clinical research of high density electrical transcranial stimulation and examination
In testing.
Description of the drawings
Fig. 1 is the wearable structure diagram schematic diagram through cranium electric current stimulating apparatus of multi-mode according to the present invention.
Fig. 2 is the output current wave schematic diagram under four kinds of stimulated current output modes according to the present invention.
Fig. 3 is power module circuitry principle design drawing according to the present invention.
Fig. 4 is output current according to the present invention and impedance monitoring circuit theory design drawing.
Main appended drawing reference explanation：
1- holds control module, the wearable modules of 2-, 21- stimulated current generation modules, 22- stimulated current output modules,
3- bluetooth transceiver modules, 4- electrodes-scalp impedance monitoring module, 5- protection modules, 6- power modules, 7- electrodes.
Specific implementation mode
Below in conjunction with the accompanying drawings, the specific implementation mode of the present invention is described in detail, it is to be understood that the guarantor of the present invention
Shield range is not restricted by specific implementation.
Unless otherwise explicitly stated, otherwise in entire disclosure and claims, term " comprising " or its change
It changes such as "comprising" or " including " etc. and will be understood to comprise stated element or component, and do not exclude other members
Part or other component parts.
As shown in Figure 1, multi-mode according to the preferred embodiment of the present invention is wearable includes through cranium electric current stimulating apparatus：Hand
Hold control module 1, wearable module 2, bluetooth transceiver module 3, electrode-scalp impedance monitoring module 4,5 power supply mould of protection module
Block 6 and multiple electrodes 7.Wherein, wearable module 2 includes stimulated current generation module 21 and stimulated current output module 22,
Bluetooth transceiver module 3 includes bluetooth sending module 31 and bluetooth receiving module 32.
It holds stimulus modality and stimulus modality corresponding stimulation parameter of the control module 1 based on input and generates control and refer to
It enabling, wherein stimulus modality includes galvanic current stimulation pattern, impulse stimulation pattern, exchanges electrical stimulation pattern and noise stimulus modality,
It is adjustable to realize a variety of stimulus modalities.Stimulated current generation module 21 is decoded analysis to control instruction, and for use
The stimulus modality and stimulation parameter that family requires export corresponding stimulated current signal.Bluetooth sending module 31 is set to hand-held control
In module 1, bluetooth sending module 31 is used to control instruction being sent to wearable module 2, and bluetooth receiving module 32 is set to can
It dresses in module 2, bluetooth receiving module 32 is for receiving control instruction.Multiple electrodes 7 are bonded with scalp, are used for stimulated current
Signal is transferred to skull and internal cerebral cortex.Electrode-scalp impedance monitoring module 4 is used to monitor the resistance between electrode and scalp
Anti- value, and impedance value is sent to hand-held control module 1, when impedance value is more than secure threshold, protection module 5 cuts off multi-mode
The wearable power supply through cranium electric current stimulating apparatus.
Therefore, of the invention to have the function of output current readback through cranium electric current stimulating apparatus, by monitoring injection head in real time
The current amplitude of skin, it is ensured that output current is within the scope of the current strength that human body head can be born.Once output current deviates pre-
Fixed setting triggers early warning circuit and generates pre-warning signal, carries out power down process at once when electric current is more than secure threshold, avoid electricity
The generation for flowing damage, to ensure that the safety of device.
Multiple stimulating electrodes that the present apparatus uses include the large electrode piece of single channel bipolar electrode, such as traditional 5cm*7cm
Electrode can also be small size electrode, such as the cylindrical electrode that radius is 1cm or so.Multi-mode is wearable to be pierced through cranium electric current
Excitation device can also include：Electric current stimulates source module and electro photoluminescence selecting module, wherein it can be single-pass that electric current, which stimulates source module,
Road electric current stimulus, can also be extended with multichannel output function, related in high density electrical transcranial stimulation to apply
Clinical research and experiment in.Electro photoluminescence selecting module is for selecting galvanic current stimulation pattern, impulse stimulation pattern, alternating current thorn
One mode in energizing mode and noise stimulus modality.Galvanic current stimulation pattern includes anode excitation mode, cathode stimulation side
Formula and pseudo- stimulation mode.Anode excitation can usually enhance the excitability of stimulation target nerve member, and cathode stimulation then reduces stimulation target
The excitability of point neuron.Puppet stimulation is used as a kind of control stimulation more, usually the lasting weak current of 15s or so.
In said program, multi-mode it is wearable through cranium electric current stimulating apparatus in galvanic current stimulation pattern, output current letter
Number with being fade-in, gradually go out buffer stage, gradually gradual change increases to stable state to output current in a period of time after stimulation is opened, and
Terminate in for the previous period that gradually gradual change decays to zero to output current in stimulation, can realize triangle be fade-in/gradually to go out constant current defeated
Go out, fade time is adjustable in 1-120s, and adjusting step-length precision is 1s, output amplitude ranging from ± 5000 μ A, amplitude adjusted step
Into 100 μ A, electric current maximum fluctuation<0.02%.
Multi-mode it is wearable through cranium electric current stimulating apparatus in impulse stimulation pattern, complete pulse cycle duration/thorn
Swash between be divided into it is adjustable in 300-2000ms, adjustings step-length be 100ms, pulse period number is adjustable in 1-500, current signal width
Value is adjustable in ± 5000uA, there is automatic compensation charge function, is 0 to ensure to inject charge total value.
Multi-mode it is wearable through cranium electric current stimulating apparatus in exchanging electrical stimulation pattern, output current signal is sinusoidal to believe
Number, in a period of time after stimulation is opened and before closing, sinusoidal signal gradually stablizes by oscillation and decays to zero.Sine letter
Number amplitude is adjustable in 0-5000uA, and adjusting step-length is 25uA, and bias current is adjustable in 0- ± 1000uA, adjusts step-length and is
10uA, sinusoidal signal frequency is adjustable in 0-5KHz, wherein in 0-500Hz frequency ranges, adjusting step-length is 0.01Hz, in 500-
In 5kHz frequency ranges, adjusting step-length is 10Hz, and phase is adjustable in 0-360 °, and phase adjusted step-length is 5 °.
In noise stimulus modality, noise signal is divided into lowpass noise and high pass noise output (broadband random normal point
Cloth, low frequency and high-frequency noise, offset and duration are adjustable).And in noise stimulus modality, signal amplitude is in 0-1500uA
Adjustable, bias current is adjustable in 0- ± 1000uA, stimulation time 0-60min, adjusts step-length 5s, and the fade in/out time exists
It is adjustable in 0-120s.
In a preferred embodiment, hand-held control module further includes user interface, and user interface has
Button control section selects the corresponding circuit output pattern of stimulus modality, output current parameter and stimulation time, thorn by button
The sharp time is adjustable in 15s-60min, and adjusting stepping is 15s.
It is corresponded to through four kinds of output stimulated current patterns that cranium electric current stimulating apparatus is supported as shown in Fig. 2, multi-mode is wearable
Current waveform schematic diagram.Wherein in current polarity, amplitude, duration and it is fade-in/gradually goes out through cranium galvanic current stimulation (tDCS) signal
It is adjustable in the parameters such as step-length, electro photoluminescence (tACS) current signal is exchanged in the amplitude of sinusoidal signal, frequency, phase, biasing through cranium
The Parameter adjustables such as current amplitude.It is worth noting that invention defines AC signal amplitude reach needed for stable state when
Between, which can also be adjusted by hand-held control module 1.
As shown in figure 3, stimulated current generation module 21 is used as kernel control chip, wave using bluetooth microcontroller (CC2541)
Shape, which generates, uses DDS chips (AD9833), and the waveform (sine etc.) that DDS is generated is amplified by AC coupled, passes through AD5444 tune
Section amplitude.Realize that baseline voltage is adjusted by two-way ADC MCP4822 and OPA2188.Waveform and baseline voltage are asked by amplifier
And circuit, it is sent to follow-on Howland current source circuits.By the width for reading the storage of high-precision digital-to-analog conversion chip
Value sequence exports the voltage signal that corresponding stimulus modality requires, then is converted to output stimulation electricity via current/charge-voltage convertor
Stream, to realize that electric current stimulates.
Described device calculates and presents load impedance by real-time sampling load voltage, and sample rate is up to, and realizes to external
The real-time monitoring of impedance.When external impedance is more than 20k Ω, show electrical transcranial stimulation electrode and scalp poor contact, described device
Current output module turn off output circuit immediately and generate pre-warning signal, prompt operating personnel electrode interface is handled,
Reduce load impedance.
The wearable power module 6 through cranium electric current stimulating apparatus of multi-mode of the present invention can generate ± 30V and -5V constant amplitudes
The DC power supply of value, DC power supply are capable of providing the output current of maximum 5mA, peak power output 0.15W, and output current is held
Error rate is less than 1%.As shown in figure 4, the power supply that electric current stimulates source module to generate negative 12V and positive and negative 30V by 12V by DCDC is independent
A plate is done, by P1 on the plant-grid connection of positive and negative 12V and positive and negative 30V to current source circuit plate.L3~L6 and capacitance together,
Simple filter circuit is constituted, to reduce the noise of power supply.U2 is LDO, from 12V to positive 5V.
Hand-held control module 1 further includes user interface, and user interface has button control section, passes through button
The corresponding circuit output pattern of stimulus modality, output current parameter and stimulation time are selected, the stimulation time is in 15s-60min
Adjustable, adjusting stepping is 15s.
In practical application scene, such as to patient into during cranium galvanic current stimulation of passing through, 2 quilt of stimulated current generation module
It is placed between subject hindbrain and neck, after electrode 7 is arranged into designated position, you can by hand-held control module 1 to stimulation electricity
It flows generation module 2 and sends control instruction, realization is stimulated through cranium.It should be pointed out that stimulated current generation module is by 12V lithium batteries
It directly powers, (DC mode 5mA) battery durable ability reaches 6 hours under stimulus modality at full capacity.Stimulated current generation module
Overall dimensions can be 5cm*5cm*1.5cm, weight 0.5kg, be truly realized portable, light and handy, wearable.
In conclusion the present invention's can realize that multi-mode exports through cranium electric current stimulating apparatus, each mode output current width
The major parameters such as value, frequency of stimulation, stimulation time are adjustable in wide range, and application flexibility is high.The device also has real-time
The function of electrode-scalp impedance is monitored, and can in real time be shown data back to hand-held control module.In concrete application ring
In border, such as encounter electrode can not be bonded completely with scalp or electrode-variation of scalp interface state (such as lose by salt water sponge electrode moisture
Lose etc.) electrode-scalp interface impedance is caused to become larger, output current will be directly affected, or increase scalp and produced with electrode contact position
Raw contact voltage.For the potential security risk for avoiding the generation of excessive voltage from bringing human body, the device support monitoring in real time,
Return and show electrode-scalp impedance, can by setting threshold value of warning and secure threshold, when impedance value is more than secure threshold into
Row early warning simultaneously carries out power down process, high safety and reliability.
The description of the aforementioned specific exemplary embodiment to the present invention is in order to illustrate and illustration purpose.These descriptions
It is not wishing to limit the invention to disclosed precise forms, and it will be apparent that according to the above instruction, can much be changed
And variation.The purpose of selecting and describing the exemplary embodiment is that explaining the specific principle of the present invention and its actually answering
With so that those skilled in the art can realize and utilize the present invention a variety of different exemplary implementation schemes and
Various chooses and changes.The scope of the present invention is intended to be limited by claims and its equivalents.
Claims (10)
1. a kind of multi-mode is wearable through cranium electric current stimulating apparatus, which is characterized in that the multi-mode is wearable to stimulate through cranium electric current
Device includes：
Hand-held control module, this holds the corresponding stimulation parameter of stimulus modality and stimulus modality of control module based on input and gives birth to
At control instruction, wherein the stimulus modality include galvanic current stimulation pattern, impulse stimulation pattern, exchange electrical stimulation pattern and
Noise stimulus modality；
Wearable module comprising stimulated current generation module and stimulated current output module, the stimulated current generation module
Analysis is decoded to the control instruction, the stimulus modality and stimulation parameter required for user is exported by the stimulated current
Module exports corresponding stimulated current signal；
Bluetooth transceiver module, the bluetooth transceiver module include bluetooth sending module and bluetooth receiving module, wherein the bluetooth hair
Module is sent to be set in the hand-held control module, for the control instruction to be sent to the wearable module, the indigo plant
Tooth receiving module is set in the wearable module, for receiving the control instruction；
Multiple electrodes, the electrode are bonded with scalp, for the stimulated current signal to be transferred to skull and internal cerebral cortex,
Electrode-scalp impedance monitoring module, the impedance described in the electrode-scalp impedance monitoring module monitors between electrode and scalp
Value, and the impedance value is sent to the hand-held control module；And
Protection module, when the impedance value is more than secure threshold, it is wearable through cranium that the protection module cuts off the multi-mode
The power supply of electric current stimulating apparatus.
2. multi-mode according to claim 1 is wearable through cranium electric current stimulating apparatus, which is characterized in that the multi-mode can
It dresses through cranium electric current stimulating apparatus and further includes：
Electric current stimulates source module, electric current stimulation source module that can be extended with multichannel output function；And
Electro photoluminescence selecting module, the electro photoluminescence selecting module is for selecting galvanic current stimulation pattern, impulse stimulation pattern, exchange
One mode in electrical stimulation pattern and noise stimulus modality.
3. multi-mode according to claim 1 is wearable through cranium electric current stimulating apparatus, which is characterized in that the direct current thorn
Energizing mode includes anode excitation mode, cathode stimulation mode and pseudo- stimulation mode.
4. multi-mode according to claim 3 is wearable through cranium electric current stimulating apparatus, which is characterized in that in the direct current
In stimulus modality, gradually gradual change increases to stable state to output current to output current signal in a period of time after stimulation is opened, and
Terminating interior output current for the previous period in stimulation, gradually gradual change decays to zero, and fade time is adjustable in 1-120s, adjusts step
Long precision is 1s, output amplitude ranging from ± 5000 μ A, 100 μ A of amplitude adjusted stepping, electric current maximum fluctuation<0.02%.
5. multi-mode according to claim 1 is wearable through cranium electric current stimulating apparatus, which is characterized in that pierced in the pulse
In energizing mode, complete pulse cycle duration is adjustable in 300-2000ms, and adjusting step-length is 100ms, and pulse period number exists
Adjustable in 1-500, current signal amplitude is adjustable in ± 5000uA.
6. multi-mode according to claim 1 is wearable through cranium electric current stimulating apparatus, which is characterized in that in the alternating current
In stimulus modality, output current signal is sinusoidal signal, and amplitude is adjustable in 0-5000uA, and adjusting step-length is 25uA, biased electrical
Stream is adjustable in 0- ± 1000uA, and adjusting step-length is 10uA, and sinusoidal signal frequency is adjustable in 0-5KHz, wherein in 0-500Hz
In frequency range, adjusting step-length is 0.01Hz, and in 500-5kHz frequency ranges, adjusting step-length is 10Hz, and phase is adjustable in 0-360 °, phase
It is 5 ° that position, which adjusts step-length,.
7. multi-mode according to claim 1 is wearable through cranium electric current stimulating apparatus, which is characterized in that pierced in the noise
In energizing mode, noise signal is divided into lowpass noise and high pass noise output.
8. multi-mode according to claim 7 is wearable through cranium electric current stimulating apparatus, which is characterized in that pierced in the noise
In energizing mode, output current signal amplitude is adjustable in 0-1500uA, and bias current is adjustable in 0- ± 1000uA, stimulation time
For 0-60min, step-length 5s is adjusted, the fade in/out time is adjustable in 0-120s.
9. multi-mode according to claim 1 is wearable through cranium electric current stimulating apparatus, which is characterized in that the hand-held control
Module further includes user interface, and the user interface has button control section, and stimulus modality is selected by button
Corresponding circuit output pattern, output current parameter and stimulation time, the stimulation time is adjustable in 15s-60min, adjusts step
Into for 15s.
10. multi-mode according to claim 1 is wearable through cranium electric current stimulating apparatus, which is characterized in that the multi-mode
Wearable through cranium electric current stimulating apparatus further includes power module, and the power module can generate the straight of the amplitudes such as ± 30V and -5V
Galvanic electricity source, the DC power supply are capable of providing the output current of maximum 5mA, peak power output 0.15W, the output current
Serious forgiveness is less than 1%.
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109200461A (en) * | 2018-10-29 | 2019-01-15 | 上海体育学院 | It is a kind of for enhance locomitivity through cranium galvanic current stimulation tights |
| CN109908476A (en) * | 2019-03-20 | 2019-06-21 | 华南理工大学 | A kind of wearable multi-mode radio neural stimulation system |
| CN110354385A (en) * | 2019-07-18 | 2019-10-22 | 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) | Through the multi-modal electric stimulation therapeutic apparatus of cranium and its application method |
| WO2021114778A1 (en) * | 2019-12-11 | 2021-06-17 | 北京理工大学 | Differential frequency electrical interference device, system, and method |
| CN112999512A (en) * | 2021-03-01 | 2021-06-22 | 安徽效隆科技有限公司 | Transcranial direct current stimulation device |
| CN113827861A (en) * | 2021-09-28 | 2021-12-24 | 上海电机学院 | Intelligent multi-channel transcranial direct current stimulation method |
| GB2608006A (en) * | 2020-08-20 | 2022-12-21 | Actegy Ltd | Apparatus for detecting electrical conductivity |
| CN115762303A (en) * | 2022-11-07 | 2023-03-07 | 深圳职业技术学院 | System construction method of transcranial magnetic stimulation coil electromagnetic field simulation system |
| CN109200461B (en) * | 2018-10-29 | 2024-04-19 | 上海体育学院 | Transcranial direct current stimulation tights for enhancing exercise capacity |
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