CN109908476B - Wearable multi-mode wireless nerve stimulation system - Google Patents
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- CN109908476B CN109908476B CN201910211807.2A CN201910211807A CN109908476B CN 109908476 B CN109908476 B CN 109908476B CN 201910211807 A CN201910211807 A CN 201910211807A CN 109908476 B CN109908476 B CN 109908476B
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- 230000007383 nerve stimulation Effects 0.000 title abstract description 6
- 230000000638 stimulation Effects 0.000 claims abstract description 25
- 210000005036 nerve Anatomy 0.000 claims abstract description 11
- 230000009471 action Effects 0.000 claims description 4
- 230000003068 static effect Effects 0.000 claims description 4
- 230000003247 decreasing effect Effects 0.000 claims description 2
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 claims description 2
- 230000004936 stimulating effect Effects 0.000 abstract description 3
- 230000008859 change Effects 0.000 abstract description 2
- 238000010586 diagram Methods 0.000 description 7
- 230000009977 dual effect Effects 0.000 description 4
- 230000001537 neural effect Effects 0.000 description 3
- 230000004044 response Effects 0.000 description 3
- 230000001276 controlling effect Effects 0.000 description 2
- 210000002569 neuron Anatomy 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000005424 photoluminescence Methods 0.000 description 1
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- 238000007920 subcutaneous administration Methods 0.000 description 1
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Abstract
The invention discloses a wearable multi-mode wireless nerve stimulation system, which applies current to a human body and stimulates deep nerves of the human body in a wearable mode. The system consists of a wireless gateway and a plurality of wearable electric stimulator nodes, wherein each electric stimulator node and a skin electrode are integrally designed, and each node is configured and controlled through the wireless gateway. The electric stimulator node has two working modes of a single node and a double node, the single node in the working mode outputs pre-modulated intermediate frequency electric pulses from the single node, and the double node in the working mode outputs continuous intermediate frequency electric pulses with certain frequency difference from the two nodes. The double-node working mode comprises a fixed working mode and a scanning working mode, and the position and the change condition of the target stimulation area can be adjusted at will. The system can achieve the purpose of stimulating the deep nerves of the human body by utilizing the portable wearable equipment.
Description
Technical Field
The invention relates to wearable equipment for stimulating deep nerves of a human body, in particular to a wearable multi-mode wireless nerve stimulation system.
Background
Traditional electro photoluminescence device mode is simple, can only provide low frequency current or direct current, and human tissue is great to low frequency current's impedance, and low frequency current's penetrability is relatively poor, can't go deep into human tissue. Along with the increase of the carrier frequency of the stimulation current, the impedance of the human body is reduced, and the penetrability of the medium-frequency current to the human tissue is far greater than that of the low-frequency current. The premodulation intermediate frequency current and the beat intermediate frequency current can simultaneously give consideration to the penetrability of the intermediate frequency current to human tissues and the low-frequency response characteristic of neurons, and can be applied to stimulating nerves at deeper subcutaneous positions of a human body. Furthermore, the electrical stimulation device is a large-scale device and includes a complicated electrode connecting wire, which has a great disadvantage in portability,
disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a wearable multi-mode wireless neural stimulation system which is controlled by a wireless gateway, the wireless gateway controls a plurality of electric stimulator nodes, and the electric stimulator nodes stimulate deep nerves of a human body in a wearable device mode. The electrical stimulator node adopts intermediate frequency current with better penetrability to human body, and effectively transmits the stimulation current to deep nerves of human body. The output current parameter of each electric stimulator node all can be adjusted wantonly through wireless gateway, can work at fixed and scanning mode, satisfies diversified demand to reach the purpose with the nervous in human deep of portable wearing equipment stimulation.
In order to achieve the purpose, the technical scheme provided by the invention is as follows: a wearable multi-mode wireless neural stimulation system is composed of a wireless gateway and a plurality of wearable electric stimulator nodes, wherein each node is configured and controlled through the wireless gateway; the output current waveform, amplitude, action time and working mode parameters of each electric stimulator node are controlled by wireless communication signals, and the output current waveform of each electric stimulator node acts on a human body through a skin electrode; the skin electrode comprises an output electrode and a grounding electrode which are mutually isolated patches, and the whole node is adsorbed on the surface of a human body by virtue of the patches; the two grounding electrodes are connected with the output electrode through a lead wire, and the other grounding electrode is integrated with the output electrode, wherein the selection of the two grounding electrodes is controlled by an independent switch.
Furthermore, the electric stimulator node outputs a medium-frequency electric pulse signal with adjustable power to a human body through the skin electrode, can stimulate nerves deep inside the human body, and has the frequency range of 1-100 kHz.
Furthermore, the electric stimulator node has two working modes of a single node and a double node: the single node working mode is that the single node independently outputs pre-modulated intermediate frequency electric pulses, and the modulation frequency range is 1-200 Hz; the working mode of the double nodes is that the two nodes cooperate with each other, each node outputs an intermediate frequency electric pulse without modulation, and the frequency difference value of the electric pulses output by the two nodes is 1-200 Hz.
Further, the dual-node operating mode is divided into two operating modes of fixing and scanning according to the mode of outputting power by the intermediate frequency electric pulse: the fixed working mode is that the power output by the two nodes is fixed, and the target stimulation area is static and unchangeable; the scanning working mode is that the power output by the two nodes is adjusted towards opposite directions, namely the output power of one node is increased while the output power of the other node is decreased, and the target stimulation area continuously moves along the cross section of the human body parallel to the skin surface where the two nodes are located.
Furthermore, the electric stimulator node consists of a CPU, a wireless transceiver, an electric pulse generator, a battery and a skin electrode, wherein the CPU is used for controlling the wireless transceiver and the electric pulse generator to work, the wireless transceiver is used for receiving a wireless control signal sent by a wireless gateway, the battery provides electric energy for the whole electric stimulator node, the electric pulse generator outputs a waveform signal with specific parameters, and the output end of the electric pulse generator is connected with the skin electrode and used for applying current to a human body.
Compared with the prior art, the invention has the following advantages and beneficial effects:
1. a plurality of wireless stimulator nodes are controlled through a wireless gateway, and the integrated design of stimulators and electrodes is adopted, so that the nerve loop and functions of a human body can be regulated and controlled in a portable and simple wearing manner.
2. The medium-frequency current with better penetrability to human body is adopted to effectively transmit the current on the body surface to the deep nerve and cause effective stimulation response, thus overcoming the great attenuation of the traditional low-frequency current and direct current in the body.
3. The multi-node medium-frequency current is adopted to stimulate the human body, a fixed working mode and a scanning working mode are provided, flexibility and adjustability are achieved, and diversified requirements are met.
Drawings
Fig. 1 is a schematic diagram of a wireless gateway controlling multiple electrical stimulator nodes.
FIG. 2 is a schematic of the output and ground electrodes of the skin electrode
Fig. 3 is a waveform diagram of the current output from the single node operating mode.
Fig. 4 is a waveform diagram of the current output by the dual node operating mode and the superimposed current.
Fig. 5 is a schematic diagram of the electrode crossover distribution for the dual node mode of operation.
FIG. 6 is a schematic diagram of the parallel distribution of electrodes and the fixed operation mode in the dual node operation mode.
FIG. 7 is a schematic diagram of the parallel electrode distribution and scanning operation mode in the dual node operation mode.
Fig. 8 is a schematic diagram of a boost amplifier circuit for an electrical stimulator node.
Detailed Description
The present invention will be further described with reference to the following specific examples.
The wearable multi-mode wireless neural stimulation system provided by the embodiment specifically comprises a plurality of electric stimulator nodes controlled by a wireless gateway, each electric stimulator node can be configured and controlled in a wireless communication mode, and output current parameters of the electric stimulator nodes, including waveform, amplitude, opening, closing, action time and the like of current, can be adjusted at will.
The electric stimulator node consists of a CPU, a wireless transceiver, an electric pulse generator, a battery and a skin electrode, the whole electric stimulator node device is adsorbed on the surface of a human body through a skin electrode patch, and no additional control circuit or control lead between the electrodes is provided. The wireless nerve stimulation system applies medium-frequency current with better penetrability to a human body in vitro to reach deep nerves of the human body. The multi-mode wireless nerve stimulation system comprises two stimulator nodes, namely a single-node working mode and a double-node working mode; the single-node working mode independently outputs pre-modulated intermediate frequency electric pulses, the double-node working mode is that two nodes cooperate with each other, each node outputs intermediate frequency electric pulses which are not modulated and have certain frequency difference, and the intermediate frequency electric pulses are mutually superposed in vivo to form low-frequency modulated intermediate frequency modulation envelope.
The double-node working mode is divided into a fixed working mode and a scanning working mode, the fixed working mode is that the power output by the two nodes is fixed, and the target stimulation area is static and unchangeable; the scanning operation mode is that the respective output powers of the two nodes are not equal, but the total amount of the two nodes is equal. The output power of the two nodes is respectively adjusted, and the target stimulation area continuously moves along the cross section of the human body parallel to the skin surface where the two nodes are located.
The two electrode arrangement modes of the double-node working mode are two, the first arrangement mode is parallel arrangement, and the second arrangement mode is cross arrangement.
The multi-mode wireless neurostimulation system according to the embodiment is explained by using fig. 1-8.
As shown in fig. 1, a wearable multi-mode wireless neurostimulation system consists of a wireless gateway 101 and a plurality of electrical stimulator nodes 102, 103, 104, 105. The wireless gateway 101 transmits wireless signals to control the plurality of electrical stimulator nodes 102, 103, 104, 105. The electrical stimulator nodes 102, 103 are in a single node mode of operation, in which the output electrode 106 and the ground electrode 107 are of an integral design. The electrostimulator nodes 104, 105 are in a dual-node mode of operation, in which the output electrode 108 and the ground electrode 109 are connected by a connecting wire. Parameters of the current output by the node can be controlled through the wireless gateway, and the controlled stimulator parameters comprise waveform, power, action time, switch and the like of the output current. The electric stimulator node consists of a CPU, a wireless transceiver, an electric pulse generator, a battery and a skin electrode, wherein the CPU controls the wireless transceiver and the electric pulse generator to work, the wireless transceiver is used for receiving wireless control signals sent by the wireless gateway, the battery provides electric energy for the whole electric stimulator node, the electric pulse generator outputs waveform signals of specific parameters, and the output end of the electric pulse generator is connected with the skin electrode and used for applying current to a human body.
As shown in fig. 2, the skin electrode comprises an output electrode 201 and two ground electrodes 202, 203. The selection of the two ground electrodes is controlled by switches 204, 205. When the switch 204 is switched on, the output electrode 201 and the grounding electrode 202 form a skin electrode, and the grounding electrode 203 is suspended and does not play a role in a human body; when the switch 205 is turned on, the output electrode 201 and the grounding electrode 203 form a skin electrode, and the grounding electrode 202 is suspended and does not act on the human body.
The electric stimulator node comprises two working modes, namely a single-node working mode and a double-node working mode. The single-node working mode outputs pre-modulated intermediate frequency electric pulses, the double-node working mode is that two nodes cooperate with each other, and each node outputs non-modulated continuous intermediate frequency electric pulses respectively.
As shown in fig. 3, the current waveform outputted by the single node operating mode has a carrier frequency of an intermediate frequency 301, a value range of 1-100kHz, a modulation frequency of a low frequency 302, and a value range of 1-200 Hz. The medium frequency is used as the carrier frequency, so that the penetrability of current to human tissues is improved, the modulation frequency is the low frequency, and the low frequency response characteristic of nerve cells is met. The target stimulation area is a region of human tissue in the vicinity of the output electrode and the selected ground electrode.
As shown in fig. 4, the current waveform output by the dual-node operating mode includes two electrical stimulator nodes. The output current waveforms 401 and 402 of the two electric stimulator nodes are continuous medium-frequency sinusoidal currents, the carrier frequency difference value of the two currents 401 and 402 is low frequency, and the low frequency range is 1-200 Hz. The two sinusoidal currents are superimposed in the target stimulation area in the body to form a low frequency modulated mid frequency current 403.
The dual-node working mode can be divided into a fixed working mode and a scanning working mode according to the mode of outputting power by intermediate-frequency electric pulses: the fixed working mode is that the power output by the two nodes is fixed, and the target stimulation area is static and unchangeable; the scanning operation mode is that the power output by the two nodes is adjusted towards opposite directions, and the output power of the two nodes is unequal but the sum of the two nodes is equal. The output power of the two nodes is respectively adjusted, the position of the target stimulation area can be adjusted, and the position of the target stimulation area continuously moves along the human body cross section parallel to the skin surface where the two nodes are located.
As shown in fig. 5, in the fixed operation mode of the dual-node operation mode, the electrodes of the two electrical stimulator nodes 501 and 502 are arranged in a crossing manner, and the respective output powers are fixed. The geometric center 503 formed by the two stimulator nodes is the target stimulation area.
As shown in fig. 6, in the fixed operation mode of the dual-node operation mode, the electrodes of the two electrical stimulator nodes 601 and 602 are arranged in parallel, and the output powers of the two electrical stimulator nodes are fixed. The geometric center 603 formed by the two stimulator nodes is the target stimulation area.
As shown in fig. 7, in the scanning operation mode of the dual-node operation mode, the electrodes of the two nodes 701 and 702 of the electrical stimulator are arranged in a crossed manner, the output power of each node gradually changes, and the output power of the two nodes is adjusted in opposite directions (for example, the output power of one node increases and the output power of the other node decreases). The output power of the electric stimulator nodes 701 and 702 is adjusted, and the target stimulation area can be adjusted randomly to change according to a certain rule. The rule follows the following rules: when the output power of the electrical stimulator node 701 is greater than the output power of the electrical stimulator node 702, the target stimulation area 703 is the side close to the smaller output power; when the output power of electrostimulator node 701 is less than the output power of electrostimulator node 702, the target stimulation zone 704 is the side near the lesser output power.
As shown in fig. 8, the boost amplifying circuit of the electrical stimulator node adopts a triode push-pull amplifying circuit, and consists of four complementary triodes SMBTA92 and SMBTA93, the low-amplitude analog signal output by the single chip microcomputer is amplified and output, and the amplified output current can reach +/-20V.
The above-mentioned embodiments are merely preferred embodiments of the present invention, and the scope of the present invention is not limited thereto, so that the changes in the shape and principle of the present invention should be covered within the protection scope of the present invention.
Claims (3)
1. A wearable multi-mode wireless neurostimulation system, characterized by: the system consists of a wireless gateway and a plurality of wearable electric stimulator nodes, wherein each node is configured and controlled through the wireless gateway; the output current waveform, amplitude, action time and working mode parameters of each electric stimulator node are controlled by wireless communication signals, and the output current waveform of each electric stimulator node acts on a human body through a skin electrode; the skin electrode comprises an output electrode and a grounding electrode which are mutually isolated patches, and the whole node is adsorbed on the surface of a human body by virtue of the patches; the two grounding electrodes are connected with the output electrode through a lead wire, and the other grounding electrode is integrated with the output electrode, wherein the selection of the two grounding electrodes is controlled by an independent switch;
the electric stimulator node has two working modes of a single node and a double node: the single node working mode is that the single node independently outputs pre-modulated intermediate frequency electric pulses, and the modulation frequency range is 1-200 Hz; the working mode of the double nodes is that the two nodes cooperate with each other, each node outputs a medium-frequency electric pulse without modulation, and the frequency difference value of the electric pulses output by the two nodes ranges from 1 Hz to 200 Hz;
the double-node working mode is divided into two working modes of fixing and scanning according to the mode of outputting power by intermediate-frequency electric pulses: the fixed working mode is that the power output by the two nodes is fixed, and the target stimulation area is static and unchangeable; the scanning working mode is that the power output by the two nodes is adjusted towards opposite directions, namely the output power of one node is increased while the output power of the other node is decreased, and the target stimulation area continuously moves along the cross section of the human body parallel to the skin surface where the two nodes are located.
2. A wearable multi-mode wireless neurostimulation system according to claim 1, characterized in that: the electric stimulator node outputs a medium-frequency electric pulse signal with adjustable power to a human body through a skin electrode, can stimulate nerves deep inside the human body, and has the frequency range of 1k-100 kHz.
3. A wearable multi-mode wireless neurostimulation system according to claim 1, characterized in that: the electric stimulator node comprises a CPU, a wireless transceiver, an electric pulse generator, a battery and a skin electrode, wherein the CPU is used for controlling the wireless transceiver and the electric pulse generator to work, the wireless transceiver is used for receiving a wireless control signal sent by a wireless gateway, the battery provides electric energy for the whole electric stimulator node, the electric pulse generator outputs a waveform signal with specific parameters, and the output end of the electric pulse generator is connected with the skin electrode and used for applying current to a human body.
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