CN107050644A - A kind of sacral nerve stimulation device of frequency of stimulation change - Google Patents
A kind of sacral nerve stimulation device of frequency of stimulation change Download PDFInfo
- Publication number
- CN107050644A CN107050644A CN201710257300.1A CN201710257300A CN107050644A CN 107050644 A CN107050644 A CN 107050644A CN 201710257300 A CN201710257300 A CN 201710257300A CN 107050644 A CN107050644 A CN 107050644A
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- CN
- China
- Prior art keywords
- frequency
- stimulation
- change
- sacral nerve
- period
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0507—Electrodes for the digestive system
- A61N1/0514—Electrodes for the urinary tract
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
Abstract
The invention discloses a kind of sacral nerve stimulation device of frequency of stimulation change, including：Two groups of stimulating electrodes, are respectively arranged in the selected stimulation point in the both sides of sacral nerve；Device is set, and setting stimulates period of change；Impulse generator, pulse is sent by two groups of stimulating electrodes；Control device, impulse generator is controlled to send low-frequency pulse to a nervus lateralis of sacral nerve by first group of stimulating electrode, high-frequency impulse is sent to another nervus lateralis by second group of stimulating electrode, until reaching the stimulation period of change, and in next stimulation period of change, exchange the frequency of stimulation signal of the sacral nerve both sides.The present invention is in the alternately high and low frequency stimulation of 2 stimulation points, it is to avoid the problem of needs multiple stimulation points, reduces the difficulty of operation.
Description
Technical field
The present invention relates to a kind of sacral nerve stimulation device, and in particular to a kind of sacral nerve stimulation dress of frequency of stimulation change
Put.
Background technology
Sacral nerve electrical stimulation device is also known as bladder pacemaker, and Sacral nerve electrical stimulation is treat bladder urination dysfunction one
Plant minimally invasive, reversible novel therapies.Sacral nerve stimulation is also referred to as sacral nerve neuromodulation, is a kind of medical electrical stimulating therapy.In urination
In terms of dysfunction, primary treatment expectant treatment (oral drugs, behaviour therapy) is invalid or can not be resistant to expectant treatment patient's
Frequent micturition, urgent urination, urge incontinence, the symptom of the non-obstructivity retention of urine.Generally it is being subcutaneously implanted programmable stimulator i.e. sacrum
Nerve stimulator, it is connected to sacral nerve by lead and sends short arc electro photoluminescence.
Because in these symptoms, nerve and brain are no longer able to effective communication, this causes the function of intestines/bladder to produce barrier
Hinder.Treatment now is imitated signal often through central nervous system and sent.One main neural route is since brain
Along spinal cord by the back of the body, this is commonly known as sacrum area.This Region control basin bottom, sphincter urethrae, bladder and enteron aisle
Daily life function.By stimulating sacral nerve（Positioned at low back）, stimulator can produce the electric signal that control basin bottom is shunk.Pushed away with the time
Move, these shrink the intensity by organ and muscle is rebuild.This effectively alleviates all symptoms of the dysfunction of urination/just, and
Them can be completely eliminated under many circumstances.
Over the course for the treatment of, the frequency of stimulation of sacral nerve stimulation is to need to change, on the one hand, in treatment different syndromes
When, it is necessary to which different frequency, on the other hand, when treating same illness, single-frequency is stimulated for a long time also easily makes patient
Tolerance is produced, answers conversion frequency to improve the effect for the treatment of.Currently, the frequency for treatment is between tens to 200 hertz.
Current conversion system is difficult to avoid producing sphincter urethrae imbalance contraction and avoid neuromuscular to the tired of stimulation while meeting
The requirement of labor.
The content of the invention
The technical problem to be solved in the present invention is to provide a kind of sacral nerve stimulation device of frequency of stimulation change, it is to avoid produces
The problem of sphincter urethrae imbalance is shunk and neuromuscular is to the fatigue of stimulation.
In order to solve the above-mentioned technical problem, the present invention provides a kind of sacral nerve stimulation device of frequency of stimulation change, including：
Two groups of stimulating electrodes, are respectively arranged in the selected stimulation point in the both sides of sacral nerve；Device is set, and setting stimulates period of change；Arteries and veins
Generator is rushed, pulse is sent by two groups of stimulating electrodes；Control device, control impulse generator passes through first group of stimulating electrode pair
One nervus lateralis of sacral nerve sends low-frequency pulse, and high-frequency impulse is sent to another nervus lateralis by second group of stimulating electrode, until
The stimulation period of change is reached, and in next stimulation period of change, exchanges the frequency of stimulation letter of the sacral nerve both sides
Number, i.e., first group stimulating electrode sends high-frequency impulse to a nervus lateralis of sacral nerve, and second group of stimulating electrode is to another nervus lateralis
Send low-frequency pulse.
Further, the frequency and amplitude of the low-frequency pulse are changes, and the frequency and amplitude of the high-frequency impulse are
Constant.
Specifically, the frequency of the low-frequency pulse is higher, then amplitude is lower；The frequency of the low-frequency pulse is lower, then width
Degree is higher.
Further, the stimulation period of change is fixed value or changing value, the setting range of the stimulation period of change
For 1-120 minutes.
Further, the stimulation period of change changes at random.
Further, the stimulation period of change is daily circulation change, and it has difference in daily different periods
Setting.
Further, the quantity of the stimulating electrode of every side of the sacral nerve is one.
Further, the quantity of the stimulating electrode of every side of the sacral nerve is multiple.
Specifically, the frequency range of the high-frequency impulse is 600Hz-2MHz, and the frequency range of the low-frequency pulse is
2Hz-120Hz。
The present invention has the advantages that：
1. the present invention empties bladder using the combination nerve electric stimulation control bladder contraction of low-and high-frequency, but is that of avoiding generation urine
Road sphincter imbalance is shunk.
2. low frequency part frequency amplitude of the present invention is change, it is to avoid fatigue of the neuromuscular to stimulation.
3. the present invention can only set 2 stimulation points, in the alternately high and low frequency stimulation of 2 stimulation points, it is to avoid need
The problem of multiple stimulation points, reduce the difficulty of operation.
Brief description of the drawings
, below will be to required in embodiment or description of the prior art in order to illustrate more clearly of technical scheme
The accompanying drawing used is briefly described, it should be apparent that, drawings in the following description are only some embodiments of the present invention, right
For those of ordinary skill in the art, on the premise of not paying creative work, it can also be obtained according to these accompanying drawings
Its accompanying drawing.
Fig. 1 is the schematic diagram of the sacral nerve stimulation device of the frequency of stimulation change of the present invention；
Fig. 2 is the schematic flow sheet of the sacral nerve stimulation device of frequency of stimulation change of the present invention.
Embodiment
The technical scheme in inventive embodiments will be clearly and completely described below, it is clear that described embodiment
Only a part of embodiment of the invention, rather than whole embodiments.Based on embodiments of the invention, ordinary skill
The every other embodiment that personnel are obtained on the premise of creative work is not made, belongs to the model that the present invention is protected
Enclose.
In one embodiment of the invention, as shown in Figure 1 and Figure 2, a kind of sacral nerve stimulation dress of frequency of stimulation change
Put, including：Two groups of stimulating electrodes, are respectively arranged in the selected stimulation point in the both sides of sacral nerve；Device is set, and setting stimulates change
Cycle；Impulse generator, pulse is sent by two groups of stimulating electrodes；Control device, control impulse generator passes through first group of thorn
The nervus lateralis for swashing electrode pair sacral nerve sends low-frequency pulse, and high frequency arteries and veins is sent to another nervus lateralis by second group of stimulating electrode
Punching, until reaching the stimulation period of change, and in next stimulation period of change, exchanges the stimulation of the sacral nerve both sides
Group stimulating electrode of frequency signal, i.e., first sends high-frequency impulse to a nervus lateralis of sacral nerve, and second group of stimulating electrode is to another
Nervus lateralis sends low-frequency pulse.
The stimulation period of change is fixed value or changing value, and the setting range of the stimulation period of change is 1-120 points
Clock.Further, the stimulation period of change changes at random.Further, the stimulation period of change is daily circulation
Change, it has different settings in daily different periods.
The low frequency stimulating is used to treat, and the high frequency stimulation produces nerve block, it is to avoid produce sphincter urethrae imbalance
Shrink.Low frequency pulse signal is amplified by amplifying circuit, and the signal of amplification is input to miniature transformer boosting, the secondary wire of transformer
Circle, so that it may the clock for the treatment of is exported, by variable resistor pressure regulation, so that it may export for treating pulse.Pulse has 3 solely
Vertical parameter, i.e. pulse voltage（Or electric current）Amplitude, pulse width and pulse interval, in order to reach preferably treatment and energy-conservation effect
Really, this 3 parameters can be adjusted.
The frequency and amplitude of the low-frequency pulse are changes, and the frequency of the low-frequency pulse is higher, then amplitude is lower；Institute
The frequency for stating low-frequency pulse is lower, then amplitude is higher, reduces discomfort of the human body to change pulse, the side that amplitude is changed over time
Formula can be straight line or curve；The frequency and amplitude of the high-frequency impulse are constant.
Stimulated next in period of change, the frequency of stimulation signal of the exchange sacral nerve both sides, described in the exchange
The low-frequency pulse of one nervus lateralis of sacral nerve is is adjusted to high-frequency impulse by the frequency of stimulation signal of sacral nerve both sides, by opposite side
The high-frequency impulse of nerve is adjusted to low-frequency pulse.
The frequency range of the high-frequency impulse is 600Hz-2MHz, and the frequency produces nerve block effect, it is to avoid produce urine
Road sphincter imbalance is shunk；The frequency range of the low-frequency pulse is 2Hz-120Hz, is the frequency range for producing bladder contraction.
So repeatedly, this stimulation mode only needs two stimulation sites, while therapeutic action is produced, it is suppressed that pair is made
Generation, and the design of pulse considers neural adaptability, improves curative effect.
For the tolerance of further reduction patient, phase, the polarity of the high frequency stimulation are all variable, each high frequencies
Waveform can be identical or different；Phase, the polarity of the low frequency stimulating are all variable, each low frequencies
Waveform can be identical or different.
The present invention has the advantages that：
1. the present invention empties bladder using the combination nerve electric stimulation control bladder contraction of low-and high-frequency, but is that of avoiding generation urine
Road sphincter imbalance is shunk.
2. low frequency part frequency amplitude of the present invention is change, it is to avoid fatigue of the neuromuscular to stimulation.
3. the present invention only sets 2 stimulation points, in the alternately high and low frequency stimulation of 2 stimulation points, it is to avoid need many
The problem of individual stimulation point, reduce the difficulty of operation.
Above disclosed is only several preferred embodiments of the invention, can not limit the power of the present invention with this certainly
Sharp scope, therefore the equivalent variations made according to the claims in the present invention, still belong to the scope that the present invention is covered.
Claims (10)
1. a kind of sacral nerve stimulation device of frequency of stimulation change, including：Two groups of stimulating electrodes, are respectively arranged two in sacral nerve
The selected stimulation point in side；Device is set, and setting stimulates period of change；Impulse generator, pulse is sent by two groups of stimulating electrodes；
Control device, control impulse generator sends low-frequency pulse by first group of stimulating electrode to a nervus lateralis of sacral nerve, passes through
Second group of stimulating electrode sends high-frequency impulse to another nervus lateralis, until the stimulation period of change is reached, and in next thorn
Swash in period of change, exchange the frequency of stimulation signal of the sacral nerve both sides, i.e., side of the first group stimulating electrode to sacral nerve
Nerve sends high-frequency impulse, and second group of stimulating electrode sends low-frequency pulse to another nervus lateralis.
2. sacral nerve stimulation device according to claim 1, it is characterised in that the frequency and amplitude of the low-frequency pulse be
Change, the frequency and amplitude of the high-frequency impulse are constant.
3. sacral nerve stimulation device according to claim 2, it is characterised in that the frequency of the low-frequency pulse is higher, then
Amplitude is lower；The frequency of the low-frequency pulse is lower, then amplitude is higher.
4. sacral nerve stimulation device according to claim 1, it is characterised in that the setting range of the stimulation period of change
For 1-120 minutes.
5. sacral nerve stimulation device according to claim 4, it is characterised in that the stimulation period of change is fixed.
6. sacral nerve stimulation device according to claim 4, it is characterised in that the stimulation period of change is change.
7. sacral nerve stimulation device according to claim 6, it is characterised in that the stimulation period of change is random change
's.
8. sacral nerve stimulation device according to claim 6, it is characterised in that the stimulation period of change is daily circulation
Change, it has different settings in daily different periods.
9. sacral nerve stimulation device according to claim 1, it is characterised in that the quantity of every group of stimulating electrode be one or
It is multiple.
10. sacral nerve stimulation device according to claim 5, it is characterised in that the frequency range of the high-frequency impulse is
600Hz-2MHz, the frequency range of the low-frequency pulse is 2Hz-120Hz.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710025498 | 2017-01-13 | ||
| CN2017100254980 | 2017-01-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107050644A true CN107050644A (en) | 2017-08-18 |
Family
ID=59599987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710257300.1A Withdrawn CN107050644A (en) | 2017-01-13 | 2017-04-19 | A kind of sacral nerve stimulation device of frequency of stimulation change |
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| Country | Link |
|---|---|
| CN (1) | CN107050644A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107789733A (en) * | 2017-11-23 | 2018-03-13 | 清华大学 | Electric pulse stimulation system and control method, the control method of electric pulse stimulation signal |
| WO2020134112A1 (en) * | 2018-12-27 | 2020-07-02 | 清华大学 | Implantable nerve stimulation device having multiple frequency modes |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102441232A (en) * | 2011-09-21 | 2012-05-09 | 北京大学人民医院 | Implanted bladder function repairing system |
| CN104363954A (en) * | 2012-03-29 | 2015-02-18 | M·J·皮特曼 | Method and apparatus for the treatment of spasmodic dysphonia |
| CN105431195A (en) * | 2012-02-21 | 2016-03-23 | 维兰德·K·沙马 | System and method for electrical stimulation of anorectal structures to treat anal dysfunction |
| CN205379548U (en) * | 2016-01-20 | 2016-07-13 | 上海力声特医学科技有限公司 | Sacrum neural stimulator |
| CN105848708A (en) * | 2013-09-03 | 2016-08-10 | 恩多斯蒂姆股份有限公司 | Methods and systems of electrode polarity switching in electrical stimulation therapy |
-
2017
- 2017-04-19 CN CN201710257300.1A patent/CN107050644A/en not_active Withdrawn
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102441232A (en) * | 2011-09-21 | 2012-05-09 | 北京大学人民医院 | Implanted bladder function repairing system |
| CN105431195A (en) * | 2012-02-21 | 2016-03-23 | 维兰德·K·沙马 | System and method for electrical stimulation of anorectal structures to treat anal dysfunction |
| CN104363954A (en) * | 2012-03-29 | 2015-02-18 | M·J·皮特曼 | Method and apparatus for the treatment of spasmodic dysphonia |
| CN105848708A (en) * | 2013-09-03 | 2016-08-10 | 恩多斯蒂姆股份有限公司 | Methods and systems of electrode polarity switching in electrical stimulation therapy |
| CN205379548U (en) * | 2016-01-20 | 2016-07-13 | 上海力声特医学科技有限公司 | Sacrum neural stimulator |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107789733A (en) * | 2017-11-23 | 2018-03-13 | 清华大学 | Electric pulse stimulation system and control method, the control method of electric pulse stimulation signal |
| WO2020134112A1 (en) * | 2018-12-27 | 2020-07-02 | 清华大学 | Implantable nerve stimulation device having multiple frequency modes |
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Application publication date: 20170818 |