CN107050645A - A kind of adjusting method of the frequency of stimulation of sacral nerve stimulator - Google Patents
A kind of adjusting method of the frequency of stimulation of sacral nerve stimulator Download PDFInfo
- Publication number
- CN107050645A CN107050645A CN201710257807.7A CN201710257807A CN107050645A CN 107050645 A CN107050645 A CN 107050645A CN 201710257807 A CN201710257807 A CN 201710257807A CN 107050645 A CN107050645 A CN 107050645A
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- China
- Prior art keywords
- frequency
- stimulation
- low
- change
- pulse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0507—Electrodes for the digestive system
- A61N1/0514—Electrodes for the urinary tract
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
Abstract
The invention discloses a kind of adjusting method of the frequency of stimulation of sacral nerve stimulator, including:Two groups of stimulating electrodes are set;Setting stimulates period of change, and the stimulation period of change is changing value;Low-frequency pulse is sent to one group of stimulating electrode, high-frequency impulse is sent to another group of stimulating electrode, until reaching the stimulation period of change;In next stimulation period of change, the frequency of stimulation signal of two groups of stimulating electrodes is exchanged.It is of the invention to empty bladder using the combination nerve electric stimulation control bladder contraction of low-and high-frequency, but it is that of avoiding generation sphincter urethrae imbalance contraction;Low frequency part frequency amplitude is change, it is to avoid fatigue of the neuromuscular to stimulation;The present invention can only set 2 stimulation points, in the alternately high and low frequency stimulation of 2 stimulation points, it is to avoid the problem of needs multiple stimulation points, reduce the difficulty of operation.
Description
Technical field
The present invention relates to sacral nerve stimulator field, and in particular to a kind of regulation side of the frequency of stimulation of sacral nerve stimulator
Method.
Background technology
Sacral nerve electrical stimulation device is also known as bladder pacemaker, and Sacral nerve electrical stimulation is the one kind for treating bladder urination dysfunction
Minimally invasive, reversible novel therapies.Sacral nerve stimulation is also referred to as sacral nerve neuromodulation, is a kind of medical electrical stimulating therapy.In urination work(
Can be in terms of obstacle, primary treatment expectant treatment (oral drugs, behaviour therapy) is invalid or urine that can not be resistant to expectant treatment patient
Frequently, urgent urination, urge incontinence, the symptom of the non-obstructivity retention of urine.Generally it is being subcutaneously implanted programmable stimulator i.e. sacrum god
Through stimulator, it is connected to sacral nerve by lead and sends short arc electro photoluminescence.
Because in these symptoms, nerve and brain are no longer able to effective communication, this causes the function of intestines/bladder to produce barrier
Hinder.Treatment now is imitated signal often through central nervous system and sent.One main neural route is since brain
Along spinal cord by the back of the body, this is commonly known as sacrum area.This Region control basin bottom, sphincter urethrae, bladder and enteron aisle
Daily life function.By stimulating sacral nerve(Positioned at low back), stimulator can produce the electric signal that control basin bottom is shunk.Pushed away with the time
Move, these shrink the intensity by organ and muscle is rebuild.This effectively alleviates all symptoms of the dysfunction of urination/just, and
Them can be completely eliminated under many circumstances.
Over the course for the treatment of, the frequency of stimulation of sacral nerve stimulation is to need to change, on the one hand, in treatment different syndromes
When, it is necessary to which different frequency, on the other hand, when treating same illness, single-frequency is stimulated for a long time also easily makes patient
Tolerance is produced, answers conversion frequency to improve the effect for the treatment of.Currently, the frequency for treatment is between tens to 200 hertz.
Current conversion system is difficult to avoid producing sphincter urethrae imbalance contraction and avoid neuromuscular to the tired of stimulation while meeting
The requirement of labor.
The content of the invention
The technical problem to be solved in the present invention is to provide a kind of adjusting method of the frequency of stimulation of sacral nerve stimulator.
In order to solve the above-mentioned technical problem, the present invention provides a kind of adjusting method of the frequency of stimulation of sacral nerve stimulator,
Comprise the following steps:
Two groups of stimulating electrodes are set;
Setting stimulates period of change, and the stimulation period of change is changing value;
Low-frequency pulse is sent to one group of stimulating electrode, high-frequency impulse is sent to another group of stimulating electrode, until reaching the stimulation
Period of change;
In next stimulation period of change, the frequency of stimulation signal of two groups of stimulating electrodes is exchanged.
Further, the frequency and amplitude of the low-frequency pulse are changes, and the frequency and amplitude of the high-frequency impulse are
Constant.
Specifically, the frequency of the low-frequency pulse is higher, then amplitude is lower;The frequency of the low-frequency pulse is lower, then width
Degree is higher.
Further, the stimulation period of change is changing value, and the setting range of the stimulation period of change is 1-120 points
Clock.
Further, the frequency of stimulation signal for exchanging two groups of stimulating electrodes includes:By the low high of one group of stimulating electrode
Frequency pulse regulation is high/low frequency pulse, is low high pulse by the high/low frequency pulse regulation of another group of stimulating electrode.
Further, in use, one of which stimulating electrode is arranged at the side of sacral nerve to sacral nerve stimulator
Stimulation point, another group of stimulating electrode be arranged at the stimulation point of the opposite side of sacral nerve.
Further, the quantity of every group of stimulating electrode is one or more.
Specifically, the frequency range of the high-frequency impulse is 600Hz-2MHz, and the frequency range of the low-frequency pulse is
2Hz-120Hz。
Present invention also offers a kind of sacral nerve stimulator, including impulse generator and stimulating electrode, wherein the pulse
Generator can adjust the frequency of stimulation of the stimulating electrode output according to the method described in one of above technical scheme.
The present invention has the advantages that:
1. the present invention empties bladder using the combination nerve electric stimulation control bladder contraction of low-and high-frequency, it is to avoid generation urethra is included
The problem of about myastasia contraction and neuromuscular are to the fatigue of stimulation.
2. low frequency part frequency amplitude of the present invention is change, it is to avoid fatigue of the neuromuscular to stimulation.
3. the present invention can only set 2 stimulation points, in the alternately high and low frequency stimulation of 2 stimulation points, it is to avoid need
The problem of multiple stimulation points, reduce the difficulty of operation.
Brief description of the drawings
, below will be to required in embodiment or description of the prior art in order to illustrate more clearly of technical scheme
The accompanying drawing used is briefly described, it should be apparent that, drawings in the following description are only some embodiments of the present invention, right
For those of ordinary skill in the art, on the premise of not paying creative work, it can also be obtained according to these accompanying drawings
Its accompanying drawing.
Fig. 1 is the schematic diagram of the flow of the inventive method.
Embodiment
The technical scheme in inventive embodiments will be clearly and completely described below, it is clear that described embodiment
Only a part of embodiment of the invention, rather than whole embodiments.Based on embodiments of the invention, ordinary skill
The every other embodiment that personnel are obtained on the premise of creative work is not made, belongs to the model that the present invention is protected
Enclose.
In one embodiment of the invention, as shown in figure 1, a kind of tune of the frequency of stimulation of sacral nerve stimulator of the invention
Section method, comprises the following steps:
Two groups of stimulating electrodes are set;
Setting stimulates period of change, and the stimulation period of change is changing value;
Low-frequency pulse is sent to one group of stimulating electrode, high-frequency impulse is sent to another group of stimulating electrode, until reaching the stimulation
Period of change;
In next stimulation period of change, the frequency of stimulation signal of two groups of stimulating electrodes is exchanged.
Further, the frequency and amplitude of the low-frequency pulse are changes, and the frequency and amplitude of the high-frequency impulse are
Constant.
Specifically, the frequency of the low-frequency pulse is higher, then amplitude is lower;The frequency of the low-frequency pulse is lower, then width
Degree is higher.
Further, the stimulation period of change is changing value, and the setting range of the stimulation period of change is 1-120 points
Clock.
Further, the frequency of stimulation signal for exchanging two groups of stimulating electrodes includes:By the low high of one group of stimulating electrode
Frequency pulse regulation is high/low frequency pulse, is low high pulse by the high/low frequency pulse regulation of another group of stimulating electrode.
Further, in use, one of which stimulating electrode is arranged at the side of sacral nerve to sacral nerve stimulator
Stimulation point, another group of stimulating electrode be arranged at the stimulation point of the opposite side of sacral nerve.The low frequency stimulating is used to treat, described
High frequency stimulation produces nerve block, it is to avoid produces sphincter urethrae imbalance and shrinks.Low frequency pulse signal is amplified by amplifying circuit, is put
Big signal is input to miniature transformer boosting, the secondary coil of transformer, so that it may the clock for the treatment of is exported, by variable
Resistance pressure regulation, so that it may export for treating pulse.Pulse has 3 independent parameters, i.e. pulse voltage(Or electric current)Amplitude, arteries and veins
Width and pulse interval are rushed, in order to reach preferably treatment and energy-saving effect, this 3 parameters can be adjusted.
The frequency and amplitude of the low-frequency pulse are changes, and the frequency of the low-frequency pulse is higher, then amplitude is lower;Institute
The frequency for stating low-frequency pulse is lower, then amplitude is higher, reduces discomfort of the human body to change pulse, the side that amplitude is changed over time
Formula can be straight line or curve;The frequency and amplitude of the high-frequency impulse are constant.
Further, the quantity of every group of stimulating electrode is one or more.
Specifically, the frequency range of the high-frequency impulse is 600Hz-2MHz, and the frequency produces nerve block effect, it is to avoid
Sphincter urethrae imbalance is produced to shrink;The frequency range of the low-frequency pulse is 2Hz-120Hz, is the frequency for producing bladder contraction
Scope.
Stimulated next in period of change, the frequency of stimulation signal of the exchange sacral nerve both sides, described in the exchange
The low-frequency pulse of one nervus lateralis of sacral nerve is is adjusted to high-frequency impulse by the frequency of stimulation signal of sacral nerve both sides, by opposite side
The high-frequency impulse of nerve is adjusted to low-frequency pulse.
So repeatedly, this stimulation mode only needs two stimulation sites, while therapeutic action is produced, it is suppressed that pair is made
Generation, and the design of pulse considers neural adaptability, improves curative effect.
For the tolerance of further reduction patient, phase, the polarity of the high frequency stimulation are all variable, each high frequencies
Waveform can be identical or different;Phase, the polarity of the low frequency stimulating are all variable, each low frequencies
Waveform can be identical or different.
The present invention has the advantages that:
1. the present invention empties bladder using the combination nerve electric stimulation control bladder contraction of low-and high-frequency, but is that of avoiding generation urine
Road sphincter imbalance is shunk.
2. low frequency part frequency amplitude of the present invention is change, it is to avoid fatigue of the neuromuscular to stimulation.
3. the present invention only sets 2 stimulation points, in the alternately high and low frequency stimulation of 2 stimulation points, it is to avoid need many
The problem of individual stimulation point, reduce the difficulty of operation.
Above disclosed is only several preferred embodiments of the invention, can not limit the power of the present invention with this certainly
Sharp scope, therefore the equivalent variations made according to the claims in the present invention, still belong to the scope that the present invention is covered.
Claims (8)
1. a kind of adjusting method of the frequency of stimulation of sacral nerve stimulator, it is characterised in that including:
Two groups of stimulating electrodes are set;
Setting stimulates period of change, and the stimulation period of change is changing value;
Low-frequency pulse is sent to one group of stimulating electrode, high-frequency impulse is sent to another group of stimulating electrode, until reaching the stimulation
Period of change;
In next stimulation period of change, the frequency of stimulation signal of two groups of stimulating electrodes is exchanged.
2. the adjusting method of the frequency of stimulation of a kind of sacral nerve stimulator according to claim 1, it is characterised in that described
The frequency and amplitude of low-frequency pulse are changes, and the frequency and amplitude of the high-frequency impulse are constant.
3. the adjusting method of the frequency of stimulation of sacral nerve stimulator according to claim 2, it is characterised in that the low frequency
The frequency of pulse is higher, then amplitude is lower;The frequency of the low-frequency pulse is lower, then amplitude is higher.
4. the adjusting method of the frequency of stimulation of sacral nerve stimulator according to claim 1, it is characterised in that the stimulation
The setting range of period of change is 1-120 minutes.
5. the adjusting method of the frequency of stimulation of sacral nerve stimulator according to claim 1, described two groups of stimulation electricity of exchange
The frequency of stimulation signal of pole includes:It is high/low frequency pulse by the low high pulse regulation of one group of stimulating electrode, another group is pierced
The high/low frequency pulse regulation for swashing electrode is low high pulse.
6. the adjusting method of the frequency of stimulation of sacral nerve stimulator according to claim 1, every group of stimulating electrode
Quantity is one or more.
7. the adjusting method of the frequency of stimulation of sacral nerve stimulator according to claim 6, it is characterised in that the high frequency
The frequency range of pulse is 600Hz-2MHz, and the frequency range of the low-frequency pulse is 2Hz-120Hz.
8. a kind of sacral nerve stimulator, including impulse generator and stimulating electrode, it is characterised in that the impulse generator can
The frequency of stimulation of the stimulating electrode output is adjusted according to the method described in one of claim 1-7.
Applications Claiming Priority (2)
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CN2017100282035 | 2017-01-13 | ||
CN201710028203 | 2017-01-13 |
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Publication Number | Publication Date |
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CN107050645A true CN107050645A (en) | 2017-08-18 |
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CN201710257807.7A Withdrawn CN107050645A (en) | 2017-01-13 | 2017-04-19 | A kind of adjusting method of the frequency of stimulation of sacral nerve stimulator |
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018106813A1 (en) * | 2016-12-06 | 2018-06-14 | Medtronic, Inc. | High frequency neurostimulation for pelvic symptom control |
US10315031B2 (en) | 2014-11-19 | 2019-06-11 | Medtronic, Inc. | Electrical stimulation to inhibit bladder and/or bowel contraction |
US10525268B2 (en) | 2016-08-23 | 2020-01-07 | Medtronic, Inc. | Delivery of independent interleaved programs to produce higher-frequency electrical stimulation therapy |
US10987515B2 (en) | 2017-10-10 | 2021-04-27 | Medtronic, Inc. | Management of electrical stimulation therapy |
US11071863B2 (en) | 2016-10-28 | 2021-07-27 | Medtronic, Inc. | Controlling electrical stimulation therapy |
US11083896B2 (en) | 2015-12-18 | 2021-08-10 | Medtronic, Inc. | High duty cycle electrical stimulation therapy |
US11116980B2 (en) | 2017-04-07 | 2021-09-14 | Medtronic, Inc. | Complex variation of electrical stimulation therapy parameters |
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CN102933255A (en) * | 2010-06-15 | 2013-02-13 | 斯凯医疗技术有限公司 | Incontinence treatment |
CN203183521U (en) * | 2013-04-25 | 2013-09-11 | 重庆绿色智能技术研究院 | Bipolar universal electrical nerve stimulator |
CN104363954A (en) * | 2012-03-29 | 2015-02-18 | M·J·皮特曼 | Method and apparatus for the treatment of spasmodic dysphonia |
CN105431195A (en) * | 2012-02-21 | 2016-03-23 | 维兰德·K·沙马 | System and method for electrical stimulation of anorectal structures to treat anal dysfunction |
CN105848708A (en) * | 2013-09-03 | 2016-08-10 | 恩多斯蒂姆股份有限公司 | Methods and systems of electrode polarity switching in electrical stimulation therapy |
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2017
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Patent Citations (5)
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CN102933255A (en) * | 2010-06-15 | 2013-02-13 | 斯凯医疗技术有限公司 | Incontinence treatment |
CN105431195A (en) * | 2012-02-21 | 2016-03-23 | 维兰德·K·沙马 | System and method for electrical stimulation of anorectal structures to treat anal dysfunction |
CN104363954A (en) * | 2012-03-29 | 2015-02-18 | M·J·皮特曼 | Method and apparatus for the treatment of spasmodic dysphonia |
CN203183521U (en) * | 2013-04-25 | 2013-09-11 | 重庆绿色智能技术研究院 | Bipolar universal electrical nerve stimulator |
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Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10315031B2 (en) | 2014-11-19 | 2019-06-11 | Medtronic, Inc. | Electrical stimulation to inhibit bladder and/or bowel contraction |
US11083896B2 (en) | 2015-12-18 | 2021-08-10 | Medtronic, Inc. | High duty cycle electrical stimulation therapy |
US11331489B2 (en) | 2015-12-18 | 2022-05-17 | Medtronic, Inc. | High duty cycle electrical stimulation therapy |
US10525268B2 (en) | 2016-08-23 | 2020-01-07 | Medtronic, Inc. | Delivery of independent interleaved programs to produce higher-frequency electrical stimulation therapy |
US11420066B2 (en) | 2016-08-23 | 2022-08-23 | Medtronic, Inc. | Delivery of independent interleaved programs to produce higher-frequency electrical stimulation therapy |
US11071863B2 (en) | 2016-10-28 | 2021-07-27 | Medtronic, Inc. | Controlling electrical stimulation therapy |
US11219763B2 (en) | 2016-10-28 | 2022-01-11 | Medtronic, Inc. | High frequency stimulation using low frequency titration gauge |
WO2018106813A1 (en) * | 2016-12-06 | 2018-06-14 | Medtronic, Inc. | High frequency neurostimulation for pelvic symptom control |
US11045650B2 (en) | 2016-12-06 | 2021-06-29 | Medtronic, Inc. | High frequency neurostimulation for pelvic symptom control |
US11116980B2 (en) | 2017-04-07 | 2021-09-14 | Medtronic, Inc. | Complex variation of electrical stimulation therapy parameters |
US10987515B2 (en) | 2017-10-10 | 2021-04-27 | Medtronic, Inc. | Management of electrical stimulation therapy |
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Application publication date: 20170818 |