CN109011145A - A kind of Multifunctional ear Vagus nerve stimulation instrument - Google Patents

A kind of Multifunctional ear Vagus nerve stimulation instrument Download PDF

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Publication number
CN109011145A
CN109011145A CN201810911083.8A CN201810911083A CN109011145A CN 109011145 A CN109011145 A CN 109011145A CN 201810911083 A CN201810911083 A CN 201810911083A CN 109011145 A CN109011145 A CN 109011145A
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CN
China
Prior art keywords
module
bluetooth
stimulation
impedance
vagus nerve
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810911083.8A
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Chinese (zh)
Inventor
王守岩
张晗
刘伟
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Fudan University
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Fudan University
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Priority to CN201810911083.8A priority Critical patent/CN109011145A/en
Publication of CN109011145A publication Critical patent/CN109011145A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M21/02Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis for inducing sleep or relaxation, e.g. by direct nerve stimulation, hypnosis, analgesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36053Implantable neurostimulators for stimulating central or peripheral nerve system adapted for vagal stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0027Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the hearing sense

Abstract

The invention belongs to the field of medical instrument technology, specially a kind of multi-functional nervus auricularis vagi stimulation instrument.Including power supply, touch controlled key, bluetooth module, control module, impulse waveform modulation module, impedance detection module, stimulating electrode, ECG module, electrocardioelectrode, audio processing modules and audio output module;It controls touch of key-press, control module and bluetooth module and forms human-computer interaction part;Impulse waveform modulation module, impedance detection module, stimulating electrode composition stimulation output par, c;The ECG module and electrocardioelectrode form cardioelectric monitor part, and real-time electrocardiosignal is sent to main control chip;The audio-frequency information that bluetooth uploads is decoded for realizing the function of bluetooth headset and is converted to audio output by audio processing modules, audio output module and bluetooth.A variety of stimulus waveforms that the present invention generates can satisfy different therapeutic schemes;The various states when usage scenario and treatment of user can be sufficiently adapted to, treatment pressure is slowed down, increase the daily practicability of user.

Description

A kind of Multifunctional ear Vagus nerve stimulation instrument
Technical field
The invention belongs to the field of medical instrument technology, and in particular to a kind of multi-functional nervus auricularis vagi stimulation instrument.
Background technique
With the fast development of accurate nervous system detection and electrical signal pattern control technique, electronic prescription (bioelectronic medicines) this new treatment method may be implemented.Especially in peripheral nervous system Regulation will will become progress emphasis.Auricular branch in vagal neck branch therein contains general somatesthesia fiber, hair From superior ganglion, it is distributed in the skin of auricle and external auditory canal outside backward.Noninvasive may be implemented in we here transcutaneous VNS(tVNS).The most organs and heart of vagus innervates respiratory system and digestive system Feeling, movement and the secretion of body of gland, for vagus nerve carry out electro photoluminescence, to epilepsy, diabetes, insomnia, depression etc. With good auxiliary therapeutic action.
The field stimulation that current nervus auricularis vagi stimulation uses is relatively fuzzyyer.So stimulation regulation is very inaccurate, There may be unnecessary problems when output stimulation therapy.If vagus nerve regulation can be such that heart rate reduces, if setting The range set is unreasonable, and patient is possible to the danger for bradycardia occur in the case where arbitrarily changing setting.
Electronic prescription seeks to make specific disease problems accurate treatment and regulation.So being wanted when stimulation The restriction of field stimulation is carried out according to Skin Resistance and for different syndromes, and doctor or patient are made according to this restriction There is certain adjustment space, realizes personalized medicine while being finally reached accurate medical treatment, making tVNS not is being simply to assist Treatment, but according to the special correct therapy of illness.
Stimulator only has simple function more, cannot be dissolved among the routine use environment of user, can give user in this way Using bringing big inconvenience.Single stimulator shape will use family, and middle use brings mental handicape in public places, in this way It can delay treating time.
Summary of the invention
The problem to be solved in the present invention is, for existing instrumental function and apparent defect, to design a kind of multi-functional Nervus auricularis vagi stimulation instrument, it is intended that solution vagal stimulation system function is single, and inconvenient for operation, the practicability is poor, and does not have There is the problem of feedback information;Stimulation and electrode condition detection feedback can be assessed to provide, can be used as the stimulator of bluetooth headset.
Multifunctional ear Vagus nerve stimulation instrument provided by the invention includes power supply, touch controlled key, bluetooth module, control mould Block, audio processing modules, impulse waveform modulation module, impedance detection module, ECG module, electrocardioelectrode, stimulating electrode and sound Frequency output module;Wherein:
The power supply provides electric energy for system, and the voltage needed for it is provided for each chip by pressure stabilizing and voltage transformation chip Value;
The control touch of key-press, control module and bluetooth module form human-computer interaction part, and the function which realizes is: setting is used Family parameter, controls stimulation mode, and control switch system measures heart rate, control system electricity by Bluetooth feedback electrode impedance state Amount obtains current stimulation status information;Control module includes main control chip and flash memory space, and main control chip parses user Control command simultaneously regulates and controls impulse stimulation circuit evolving stimulus waveform, and impedance is believed between main control chip can obtain stimulating electrode before stimulation Breath, and the current electrode impedance state of intelligent distinguishing is if appropriate for implementing to stimulate, by information by Bluetooth feedback to host computer, Flash memory space can store a certain number of status informations, and storage in the case where interrupting is wirelessly connected with reply and needs to send out The data sent send data when waiting connection normal;
The impulse waveform modulation module, impedance detection module, stimulating electrode composition stimulation output par, c;Impedance detection module is used Impedance between detecting electrode, and by information feedback to control module, effect is detecting electrode state if appropriate for the electric thorn of progress Swash, prompts user to adjust electrode if electrode wears exception or need cleaning skin;Impulse waveform modulation module is for obtaining The control command of main control chip is taken to generate stimulus waveform, which has a degree of adaptive ability, is adapted to certain Impedance fluctuations in range simultaneously generate stable pulse waveform signal;Stimulating electrode and skin contact export boost pulse;
The ECG module and electrocardioelectrode form cardioelectric monitor part, and real-time electrocardiosignal is sent to main control chip;The heart Electric module is used to monitor the heart rate of user;Pass through the measurement of EGC parameter, it can be estimated that therapeutic effect enables people to basis These parameters adjust stimulation output in time, reach optimal therapeutic effect;
The audio processing modules, audio output module and bluetooth can upload bluetooth for realizing the function of bluetooth headset Audio-frequency information decode and be converted to audio output.
Multifunctional ear Vagus nerve stimulation instrument of the invention, overall design are the moulding of bluetooth headset, fully take into account use Family experience, will not be because of being that a kind of special therapeutic equipment makes user lower use has obstacle at heart in public.
Multifunctional ear Vagus nerve stimulation instrument of the invention, electrocardioelectrode are located inside bluetooth headset, and user is made directly to wear Electrocardiosignal can be directly measured when wearing, and increase the convenience of test.
Multifunctional ear Vagus nerve stimulation instrument of the invention, stimulating electrode are connected in system by general-purpose interface, Be conducive to the maintenance of system.
Multifunctional ear Vagus nerve stimulation instrument of the invention, user can pass through bluetooth ear when carrying out stimulation therapy Machine sowing is put the music on, and pressure when remissive treatment, mood of releiving promotes therapeutic effect.
The integrated system of Multifunctional ear Vagus nerve stimulation instrument of the invention, bluetooth headset and cardioelectric monitor, function is more Multiplicity, including treatment, assessment and routine use.This mode increases the use value of system, increases the viscosity of user, can Realize that user uses on time, it is ensured that user can complete entire therapeutic process.
Multifunctional ear Vagus nerve stimulation instrument of the invention, can produce the voltage value of different amplitudes, frequency and pulsewidth, can To be directed to different treatment scene and disease.
Compared with other technologies, the invention has the following advantages that
Cardioelectric monitor is increased on the basis of nervus auricularis vagi stimulation, the function of impedance detection and bluetooth headset can basis Impedance parameter feeds back to user's electrode condition, assesses stimulation state by electrocardio, while can also monitor when inirritative Changes in heart rate.The a variety of stimulus waveforms generated can satisfy different therapeutic schemes.Integrated bluetooth headset function, is adequately examined Consider required state when the usage scenario and treatment of user, treatment pressure can be slowed down, increases in user's daily life Practicability.
Detailed description of the invention
Fig. 1 invention's principle block diagram.
Fig. 2 ear stimulation sites schematic diagram.
Fig. 3 structure of the invention component combination diagram.
Specific embodiment
Below in conjunction with the drawings and specific embodiments, the invention will be further described:
A kind of systematic schematic diagram of Multifunctional ear Vagus nerve stimulation instrument, as shown in Figure 1, including power supply, touch controlled key, bluetooth mould Block, control module, audio processing modules, impulse waveform modulation module, impedance monitoring module, ECG module, stimulating electrode and sound Frequency output module.A combination thereof structure is as shown in Figure 3.
Power module uses the rechargeable lithium battery of high-energy density, while meeting the supply of system components electricity, There is smaller volume.Touch controlled key includes that equipment power switch button and nervus auricularis vagi stimulation start and stop control button. Bluetooth module uses multimode bluetooth, can connect multiple equipment, and bluetooth module is separately connected audio processor and control mould Block is audio-frequency information with audio processor Content of communciation, and the content communicated with control module is control information and status information.Control The function of molding block is the waveform for controlling the stimulation output of nervus auricularis vagi stimulator, acquires electrocardiosignal, controls bluetooth connection, It is interacted with user, sends status information, and by status command storage into Flash.Audio processing modules and bluetooth connect It connects, receives audio signal, the audio output portion of rear end will be sent to after Audio Signal Processing.Impulse waveform modulation module and thorn Swash electrode composition stimulation output par, c, the stimulation parameter of control module transmission can be received, treatment institute is generated according to stimulation parameter The voltage needed, pulsewidth and frequency, and have certain adaptive ability for the Skin Resistance of variation, it can become in a constant impedance Changing in range keeps the waveform of output constant.The function that impedance detection module is realized is the impedance between detecting electrode, and be will test The impedance information feedback arrived to control module, control module can according to different impedance values by information by Bluetooth feedback to using Family, respectively electrode delamination, inter-electrode impedance is excessively high to be needed to clear up skin, can carry out these three states of stimulation therapy.Electrocardio Module and electrocardioelectrode form electrocardiogram acquisition part, and effect is to detect the electrocardiosignal of skin surface and be transmitted to electrocardiosignal Main control chip, control chip carry out brief processing and assessment to signal, and by electrocardiosignal get well analysis result be transmitted to it is upper Machine is checked for user.
It can be smart phone with the upper computer equipment of bluetooth connection or other being capable of compatible bluetooth audio and data biography The hardware system of transfer device.Host computer client can include stimulus waveform selection, including stimulation with the information of stimulator interaction Amplitude, pulsewidth and frequency, the feedback information for receiving stimulator includes electrocardiosignal, and electrocardiosignal assessment result and impedance are surveyed Measure result.Host computer client can realize the function that audio plays by bluetooth and the connection of the audio output portion of stimulator.
External structure is designed using Headphone structure, is carried and used convenient for user, and the electrode of stimulator passes through general Interface is connected with Headphone structure, increases the flexibility of stimulation, while can replace.

Claims (5)

1. a kind of Multifunctional ear Vagus nerve stimulation instrument, which is characterized in that include power supply, touch controlled key, bluetooth module, control mould Block, impulse waveform modulation module, impedance detection module, stimulating electrode, ECG module, electrocardioelectrode, audio processing modules and sound Frequency output module;Wherein:
The power supply provides electric energy for system, and the voltage needed for it is provided for each chip by pressure stabilizing and voltage transformation chip Value;
The control touch of key-press, control module and bluetooth module form human-computer interaction part, and the function which realizes is: setting is used Family parameter, controls stimulation mode, and control switch system measures heart rate, control system electricity by Bluetooth feedback electrode impedance state Amount obtains current stimulation status information;Control module includes main control chip and Flash memory space, and main control chip parses user Control command simultaneously regulates and controls impulse stimulation circuit evolving stimulus waveform, and impedance is believed between main control chip obtains stimulating electrode before stimulation Breath, and information is passed through Bluetooth feedback to host computer if appropriate for stimulation is implemented by the current electrode impedance state of intelligent distinguishing; Flash memory space is wirelessly connected storage in the case where interrupting with reply and needs to send out for storing a certain number of status informations The data sent send data when waiting connection normal;
The impulse waveform modulation module, impedance detection module, stimulating electrode composition stimulation output par, c;Impedance detection module is used Impedance between detecting electrode, and by information feedback to control module, effect is that detecting electrode state is electric if appropriate for carrying out Stimulation;Impulse waveform modulation module is used to obtain the control command of main control chip, and generates stimulus waveform, which has certain The adaptive ability of degree is adapted to a certain range of impedance fluctuations and generates stable pulse waveform signal;Stimulation electricity Pole and skin contact export boost pulse;
The ECG module and electrocardioelectrode form cardioelectric monitor part, and real-time electrocardiosignal is sent to main control chip;The heart Electric module is used to monitor the heart rate of user;Therapeutic effect is assessed by the measurement of EGC parameter, is enabled people to according to these Parameter adjusts stimulation output in time, reaches optimal therapeutic effect;
The audio processing modules, audio output module and bluetooth, for realizing the function of bluetooth headset, the sound that bluetooth is uploaded Frequency information decodes and is converted to audio output.
2. Multifunctional ear Vagus nerve stimulation instrument according to claim 1, which is characterized in that overall design is bluetooth headset Moulding.
3. Multifunctional ear Vagus nerve stimulation instrument according to claim 2, which is characterized in that electrocardioelectrode is set to bluetooth Inside earphone, electrocardiosignal can be directly measured when wearing user directly.
4. Multifunctional ear Vagus nerve stimulation instrument according to claim 1, which is characterized in that stimulating electrode is connect by general Mouth is connected in system.
5. Multifunctional ear Vagus nerve stimulation instrument according to claim 1, which is characterized in that user is carrying out stimulation therapy When can play music by bluetooth headset, pressure when remissive treatment, mood of releiving promotes therapeutic effect.
CN201810911083.8A 2018-08-10 2018-08-10 A kind of Multifunctional ear Vagus nerve stimulation instrument Pending CN109011145A (en)

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Application Number Priority Date Filing Date Title
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109656417A (en) * 2019-01-11 2019-04-19 深圳市乔威电源有限公司 A kind of touch control device
CN109731221A (en) * 2019-01-11 2019-05-10 湖北三江航天红峰控制有限公司 A kind of Multifunctional nerve muscular electrostimulation device
CN109925599A (en) * 2019-03-25 2019-06-25 李君� Ear's vagus nerve electrical stimulation device and its electrical stimulation method
CN110215607A (en) * 2019-05-31 2019-09-10 Oppo广东移动通信有限公司 Massage method and device based on electro photoluminescence
CN110507907A (en) * 2019-08-15 2019-11-29 静思(香港)有限公司 Intelligent secondary buck instrument and its working method
CN112315445A (en) * 2020-11-11 2021-02-05 深圳市因特迈科技有限公司 Wearable sweat monitoring device
CN112690800A (en) * 2020-12-03 2021-04-23 未来穿戴技术有限公司 Electrocardiogram measuring method and device, massage equipment and storage medium

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US9415220B1 (en) * 2012-07-31 2016-08-16 Synchromax, Inc. Auricular stimulation for inflammatory parasympathetic diseases
WO2017040741A1 (en) * 2015-09-04 2017-03-09 Scion Neurostim, Llc Systems, devices and methods for galvanic vestibular stimulation having an envelope modulation
CN106581854A (en) * 2016-11-16 2017-04-26 西安交通大学 Transcranial direct current stimulation device and work method thereof
CN107247886A (en) * 2017-07-18 2017-10-13 重庆锦垚生物科技有限公司 A kind of remote rehabilitation system based on internet

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9415220B1 (en) * 2012-07-31 2016-08-16 Synchromax, Inc. Auricular stimulation for inflammatory parasympathetic diseases
WO2017040741A1 (en) * 2015-09-04 2017-03-09 Scion Neurostim, Llc Systems, devices and methods for galvanic vestibular stimulation having an envelope modulation
CN106581854A (en) * 2016-11-16 2017-04-26 西安交通大学 Transcranial direct current stimulation device and work method thereof
CN107247886A (en) * 2017-07-18 2017-10-13 重庆锦垚生物科技有限公司 A kind of remote rehabilitation system based on internet

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109656417A (en) * 2019-01-11 2019-04-19 深圳市乔威电源有限公司 A kind of touch control device
CN109731221A (en) * 2019-01-11 2019-05-10 湖北三江航天红峰控制有限公司 A kind of Multifunctional nerve muscular electrostimulation device
CN109925599A (en) * 2019-03-25 2019-06-25 李君� Ear's vagus nerve electrical stimulation device and its electrical stimulation method
CN110215607A (en) * 2019-05-31 2019-09-10 Oppo广东移动通信有限公司 Massage method and device based on electro photoluminescence
CN110507907A (en) * 2019-08-15 2019-11-29 静思(香港)有限公司 Intelligent secondary buck instrument and its working method
CN112315445A (en) * 2020-11-11 2021-02-05 深圳市因特迈科技有限公司 Wearable sweat monitoring device
CN112690800A (en) * 2020-12-03 2021-04-23 未来穿戴技术有限公司 Electrocardiogram measuring method and device, massage equipment and storage medium

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Application publication date: 20181218