CN109173042B - Vagus nerve stimulation device for weight reduction - Google Patents

Vagus nerve stimulation device for weight reduction Download PDF

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Publication number
CN109173042B
CN109173042B CN201811161573.7A CN201811161573A CN109173042B CN 109173042 B CN109173042 B CN 109173042B CN 201811161573 A CN201811161573 A CN 201811161573A CN 109173042 B CN109173042 B CN 109173042B
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electrode
positive electrode
stimulation
controller
fixing device
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CN109173042A (en
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秦伟
任晓林
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Shenzhen Boweidong Intelligent Health Technology Co Ltd
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Shenzhen Boweidong Intelligent Health Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0484Garment electrodes worn by the patient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36036Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the outer, middle or inner ear

Abstract

The invention discloses a vagus nerve stimulation device for weight loss, comprising: the electrode fixing device comprises a controller, a stimulation signal generator and two electrode fixing devices, wherein each electrode fixing device is provided with a positive electrode and a negative electrode, and each electrode fixing device is connected with the stimulation signal generator; the electrode fixing device is provided with an earplug and a hook, the earplug is correspondingly contacted with a concha cavity of a person, the hook is correspondingly contacted with a concha boat of the person, and the positive electrode and the negative electrode are distributed on the earplug and the hook. The vagus nerve stimulation device for losing weight can treat diseases such as obesity and the like through vagus nerve ear branches, does not need a patient to take medicines, does not need to carry out an implantation operation, does not need to carry out transcranial stimulation, has low cost, and does not bring adverse reactions and side effects to the patient.

Description

Vagus nerve stimulation device for weight reduction
Technical Field
The invention belongs to the field of medical health-care devices, and particularly relates to a vagus nerve stimulation device for losing weight.
Background
The vagus nerve is the 10 th cranial nerve, the longest and most widely distributed pair of cranial nerves, and contains four fibrous components, somatosensory fibers, visceral sensory fibers, somatotrophic fibers and visceral motor fibers, which govern most organs of the respiratory and digestive systems as well as the sensation, movement and secretion of the glands of the heart. It is found that obesity symptoms are closely related to vagus nerve, and the traditional treatment method is drug treatment aiming at the symptoms, but the drug taking for a long time brings inevitable side effect influence. Auricles have abundant innervation, and the auricular branches of the vagus nerve are the only peripheral pathways that can reach the cerebral cortex and are also closely related to visceral functions. The existing electric stimulation scheme aiming at obesity needs to place the stimulator on the intestines and the stomach or the spinal cord through a minimally invasive operation, the operation risk is high, the device is damaged and is not easy to replace, the price is high, the drug therapy takes effect slowly, side effects are caused, the adverse reaction is more due to transcranial direct current stimulation and repeated transcranial magnetic stimulation, and the stimulation is not easy to be accepted by patients.
Disclosure of Invention
In view of the above, the present invention is directed to a vagus nerve stimulation device for weight loss, which can treat obesity symptoms through vagus nerve ear branches without taking drugs, performing an implantation operation, performing transcranial stimulation, and causing no adverse reaction or side effect to patients.
The invention provides a vagus nerve stimulation device for weight loss, comprising: the electrode fixing device comprises a controller, a stimulation signal generator and two electrode fixing devices, wherein each electrode fixing device is provided with a positive electrode and a negative electrode, and each electrode fixing device is connected with the stimulation signal generator; the electrode fixing device is provided with earplugs and hooks, the earplugs are correspondingly contacted with a concha cavity of a person, the hooks are correspondingly contacted with a concha boat of the person, and the positive electrodes and the negative electrodes are distributed on the earplugs and the hooks.
According to the vagus nerve stimulation device for weight loss, the controller controls the stimulation signal transmitter to generate a voltage stimulation signal and transmits the voltage stimulation signal to the positive electrode and the negative electrode in the electrode fixing device through the leads, the positive electrode and the negative electrode are respectively arranged on the earplugs and the hooks on the electrode fixing device, or conversely are respectively arranged on the hooks and the earplugs on the electrode fixing device, the electrodes on the earplugs are correspondingly contacted with the cavum concha of a person, and the electrodes on the hooks are correspondingly contacted with the cymba concha of the person, so that vagus nerve ear branches can be stimulated, the appetite control center of the brain can be regulated, and further, the appetite is reduced, and the fat and the weight are reduced. The stimulator does not need to be placed in the body, can achieve the same effect of the same treatment mode, is safe and reliable, does not need transcranial stimulation, does not cause adverse reaction of patients, and is easy to be accepted by the patients.
The vagal nerve stimulation device for weight loss of the present invention also has the following optional features.
Optionally, the mobile phone further comprises a bluetooth module, and the bluetooth module can be in signal connection with a wireless terminal such as a mobile phone.
According to the vagus nerve stimulation device for losing weight, the Bluetooth module comprises a CC541 Bluetooth chip and a bypass circuit thereof, the CC2540 is a single-mode BLE chip and is a combination of Bluetooth RF and 8051, and the device is provided with FLASH and an 8kB RAM and is suitable for communication with less data and low frequency.
Optionally, the stimulation signal generator comprises a boost circuit module and an ADC converter connected between the boost circuit module and the signal output of the controller.
According to the vagus nerve stimulation device for weight loss, the ADC converter converts the digital signal output by the controller into a modulus signal of a waveform, and the modulus signal is amplified by the booster circuit module to form a voltage stimulation signal.
Optionally, the boost module includes a voltage source, an inductor is connected to the positive pole of the voltage source, a triode is connected between the inductor and the negative pole of the voltage source, a capacitor is further connected in parallel between the inductor and the negative pole of the voltage source, a diode is arranged between the capacitor and the inductor, the allowable current direction of the diode points to the capacitor, the positive pole of the capacitor is directly or indirectly connected with the positive pole, and the ADC converter is connected with the signal input end of the triode.
According to the vagus nerve stimulation device for weight loss, when the signal receiving end of the triode receives a signal sent by the controller, the other two ends of the triode are conducted and are equivalent to a lead, at the moment, the voltage input by the voltage source flows through the inductor, the diode is placed in the capacitor to discharge to the ground, the current on the inductor linearly increases at a certain ratio due to the fact that the input direct current is direct current, and energy is stored in the inductor along with the increase of the current of the inductor. When the triode is cut off, the original circuit is disconnected, the inductor discharges through the new circuit, namely, the inductor starts to charge the capacitor, the voltage at two ends of the capacitor rises, and the boosting is finished.
Optionally, a plurality of gain amplifiers are connected between the positive electrode of the capacitor and the positive electrode.
According to the vagus nerve stimulation device for weight loss of the present invention, the voltage signal of the capacitor can be amplified to a predetermined intensity by the gain amplifier PGA to stimulate the vagus nerve of the ear branch of the human.
Optionally, the output voltage of the positive electrode is in the range of 9-30V.
According to the vagus nerve stimulation device for losing weight, the stimulation circuit is constant current, the size of a stimulation gear is marked by different voltages, a 5V power supply uses an adjustable resistor for voltage division to adjust the output voltage of a voltage source, the voltage is boosted to 9V through a booster circuit and then boosted to the maximum voltage of 30V through a transformer, and in order to ensure that the final output current of a current control circuit is constant, a constant current source circuit is formed by two operational amplifiers.
Optionally, the method further comprises: the stimulation device comprises a shell, wherein the shell is internally provided with a controller, a stimulation signal generator and a display screen, the shell is also provided with a key, the key is connected with a signal input end of the controller, and the display screen is connected with a signal output end of the controller.
According to the vagus nerve stimulation device for the ear, parameters such as the intensity, frequency, waveform, mode, time and the like of the stimulation signal can be selected and adjusted through keys, and the display screen can display various treatment information and device information through a software interface, such as options of the stimulation signal and corresponding parameters. And the whole equipment is small in size and convenient to carry, so that the patient can carry and use the equipment at any time easily, and the daily requirements of the patient are met.
Optionally, the electrode fixing device further comprises an electrode socket, and the electrode fixing device is connected with the electrode socket through a lead and a plug.
According to the vagus nerve stimulation device for ears, the number of the electrode sockets is two, each pair of the electrode sockets is respectively and correspondingly connected with a positive electrode plug and a negative electrode plug, the positive electrode plug is connected with a positive electrode on the electrode fixing device through a lead, and the negative electrode plug is connected with a negative electrode on the electrode fixing device through a lead.
Optionally, the display device further comprises a power supply, and the power supply supplies power to the controller and the display screen.
According to the vagus nerve stimulation device of the ear, the power supply mainly supplies power to the controller and the display screen, so that the controller and the display screen can operate.
Optionally, a charging socket is further disposed on the housing, and the charging socket is connected to the power supply.
According to the vagus nerve stimulation device of the ear, the power supply can be charged through the charging jack.
Drawings
Some specific embodiments of the invention will be described in detail hereinafter, by way of illustration and not limitation, with reference to the accompanying drawings. The same reference numbers in the drawings identify the same or similar elements or components. Those skilled in the art will appreciate that the drawings are not necessarily drawn to scale. In the drawings:
FIG. 1 is a schematic block diagram of the system architecture of one embodiment of the vagal nerve stimulation device for weight loss of the present invention;
fig. 2 is a schematic structural diagram of an electrode fixing device in the vagus nerve stimulation apparatus for weight loss according to the present invention;
FIG. 3 is a schematic block diagram of one embodiment of a boost circuit module in the vagal nerve stimulation device for weight loss in accordance with the present invention;
fig. 4 is a schematic structural diagram of an embodiment of the vagal nerve stimulation device for weight loss of the present invention.
In the above figures: 1, a controller; 2 a stimulation signal generator; 3 an electrode fixing device; 301 positive electrode; 302 a negative electrode; 303 an earplug; 304, hooking; 4, pressing a key; 5 a booster circuit module; 6ADC converter; 7, a shell; 701 electrode socket; 702 a charging socket; and 8, displaying a screen.
Detailed Description
Referring to fig. 1 and 2, an embodiment of the present invention provides a vagal nerve stimulation device for weight loss, including: the electrode fixing device comprises a controller 1, a stimulation signal generator 2 and two electrode fixing devices 3, wherein each electrode fixing device 3 is provided with a positive electrode 301 and a negative electrode 302, and each electrode fixing device 3 is connected with the stimulation signal generator 2; wherein, an earplug 303 and a hook 304 are arranged on the electrode fixing device 3, the earplug 303 corresponds to a contact concha cavity of a person, the hook 304 corresponds to a contact concha boat, and the positive electrode 301 and the negative electrode 302 are distributed on the earplug 303 and the hook 304.
In the above embodiment, the controller 1 controls the stimulation signal transmitter to generate the voltage stimulation signal, and transmits the voltage stimulation signal to the positive electrode 301 and the negative electrode 302 in the electrode fixing device 3 through the lead, the positive electrode 301 and the negative electrode 302 are respectively arranged on the ear plug 303 and the hook 304 on the electrode fixing device 3, or conversely, the positive electrode 301 and the negative electrode 302 are respectively arranged on the hook 304 and the ear plug 303 on the electrode fixing device 3, the electrode on the ear plug 303 correspondingly contacts the cavum concha of a person, and the electrode on the hook 304 correspondingly contacts the cymba concha of the person, so that the vagus nerve ear can be stimulated, the brain appetite control center can be regulated, and the appetite can be further reduced, and the fat and weight can be reduced. The stimulator does not need to be placed in the body, can achieve the same effect of the same treatment mode, is safe and reliable, does not need transcranial stimulation, does not cause adverse reaction of patients, and is easy to be accepted by the patients.
According to an embodiment of the invention, the mobile phone further comprises a Bluetooth module, and the Bluetooth module can be in signal connection with a wireless terminal such as a mobile phone.
In the above embodiment, the bluetooth module is composed of a CC541 bluetooth chip and its bypass circuit, the CC2540 is a single-mode BLE chip, which is a combination of bluetooth RF and 8051, and its own FLASH and 8kB RAM are suitable for communication with less data and low frequency.
Referring to fig. 1, according to an embodiment of the present invention, the stimulation signal generator 2 includes a boost circuit module 5 and an ADC converter 6, and the ADC converter 6 is connected between the boost circuit module 5 and a signal output terminal of the controller 1.
In the above embodiment, the ADC converter 6 converts the digital signal output by the controller 1 into a modulus signal of a waveform, and the modulus signal is amplified by the boost circuit module 5 to form a voltage stimulation signal.
Referring to fig. 3, according to an embodiment of the present invention, the boost module includes a voltage source, an inductor is connected to an anode of the voltage source, a transistor is connected between the inductor and a cathode of the voltage source, a capacitor is further connected in parallel between the inductor and the cathode of the voltage source, a diode is disposed between the capacitor and the inductor, a direction of an allowed current of the diode points to the capacitor, an anode of the capacitor is directly or indirectly connected to the anode 301, and the ADC converter 6 is connected to a signal input terminal of the transistor.
In the above embodiment, when the signal receiving terminal of the transistor receives the signal sent by the controller 1, the other two terminals of the transistor are connected, which is equivalent to a conducting wire, at this time, the voltage input by the voltage source flows through the inductor, the diode places the capacitor to discharge to ground, and since the input is direct current, the current on the inductor linearly increases at a certain rate, and as the current of the inductor increases, the energy is stored in the inductor. When the triode is cut off, the original circuit is disconnected, the inductor discharges through the new circuit, namely the inductor starts to charge the capacitor, the voltage at the two ends of the capacitor rises, and the voltage boosting is finished.
According to an embodiment of the present invention, a plurality of gain amplifiers are connected between the positive electrode of the capacitor and the positive electrode 301.
In the above embodiment, the voltage signal of the capacitor may be amplified to a predetermined intensity by the gain amplifier PGA, so as to stimulate the vagus nerve of the ear branch of the human.
According to an embodiment of the present invention, the output voltage of the positive electrode 301 ranges from 9 to 30V.
In the above embodiment, the stimulation circuit is a constant current, the size of the stimulation gear is indicated by different voltages, the 5V power supply uses an adjustable resistor to divide the voltage to adjust the output voltage of the voltage source, the voltage is increased to 9V through the voltage boosting circuit, and then the voltage is increased to 30V at most through the transformer, so as to ensure that the final output current of the current control circuit is constant, and two operational amplifiers form a constant current source circuit.
Referring to fig. 4, according to an embodiment of the present invention, further comprising: the stimulation device comprises a shell 7, wherein the controller 1, the stimulation signal generator 2 and a display screen 8 are arranged in the shell 7, a key 4 is further arranged on the shell 7, the key 4 is connected with a signal input end of the controller 1, and the display screen 8 is connected with a signal output end of the controller 1.
In the above embodiment, the selection and adjustment of parameters such as the intensity, frequency, waveform, mode and time of the stimulation signal can be selected through the keys 4, and the display screen 8 can display various treatment information and device information through a software interface, such as the options of the stimulation signal and corresponding parameters. And the whole equipment is small in size and convenient to carry, so that the patient can carry and use the equipment at any time easily, and the daily requirements of the patient are met.
According to an embodiment of the present invention, the electrode fixing device further comprises an electrode socket 701, and the electrode fixing device 3 is connected with the electrode socket 701 through a lead and a plug.
In the above embodiment, the electrode sockets 701 have two pairs, each pair is correspondingly connected with a positive plug and a negative plug, the positive plug is connected with the positive electrode 301 on the electrode fixing device 3 through a lead, and the negative plug is connected with the negative electrode 302 on the electrode fixing device 3 through a lead.
According to an embodiment of the present invention, a power supply is further included, which supplies power to the controller 1 and the display screen 8.
In the above embodiment, the power supply mainly supplies power to the controller 1 itself and the display screen 8, so that the controller 1 and the display screen 8 can operate.
According to an embodiment of the present invention, a charging socket 702 is further disposed on the housing 7, and the charging socket 702 is connected to the power supply.
In the above embodiment, the power supply may be charged through the charging inlet 702.
The above description is only for the preferred embodiment of the present application, but the scope of the present application is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present application should be covered within the scope of the present application. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.

Claims (6)

1. A vagal nerve stimulation device for weight loss, comprising: the electrode fixing device comprises a controller (1), a stimulation signal generator (2) and two electrode fixing devices (3), wherein each electrode fixing device (3) is provided with a positive electrode (301) and a negative electrode (302), the controller (1) is electrically connected with a signal receiving end of the stimulation signal generator (2), and each electrode fixing device (3) is connected with the stimulation signal generator (2);
wherein, an earplug (303) and a hook (304) are arranged on the electrode fixing device (3), the earplug (303) is correspondingly contacted with a concha cavity of a person, the hook (304) is correspondingly contacted with a concha boat of the person, the positive electrode (301) and the negative electrode (302) are distributed on the earplug (303) and the hook (304), the positive electrode (301) on the earplug (303) is correspondingly contacted with the concha cavity of the person, and the negative electrode (302) on the hook (304) is correspondingly contacted with the concha boat of the person, so as to stimulate vagus nerve ear branches;
the stimulation signal generator (2) comprises a booster circuit module (5) and an ADC converter (6), the ADC converter (6) is connected between the booster circuit module (5) and a signal output end of the controller (1), the booster circuit module (5) comprises a voltage source, an inductor is connected to the positive electrode of the voltage source, a triode is connected between the inductor and the negative electrode of the voltage source, a capacitor is connected between the inductor and the negative electrode of the voltage source in parallel, a diode is arranged between the capacitor and the inductor, the allowed current direction of the diode points to the capacitor, the positive electrode of the capacitor is directly or indirectly connected with the positive electrode, the ADC converter (6) is connected with the signal input end of the triode, and a plurality of gain amplifiers are connected between the positive electrode of the capacitor and the positive electrode (301), the output voltage range of the positive electrode (301) is 9-30V, and the current output end of the diode is connected with two operational amplifiers to form a constant current source circuit.
2. The vagus nerve stimulation device for weight loss according to claim 1, further comprising a bluetooth module, wherein the bluetooth module is connected to a wireless terminal such as a mobile phone.
3. The vagal stimulation device for weight loss according to claim 1, further comprising: the stimulation device comprises a shell (7), wherein the shell (7) is internally provided with the controller (1), the stimulation signal generator (2) and a display screen (8), the shell (7) is further provided with a key (4), the key (4) is connected with a signal input end of the controller (1), and the display screen (8) is connected with a signal output end of the controller (1).
4. The vagus nerve stimulation device for weight loss according to claim 3, further comprising an electrode socket (701), wherein the electrode fixation device (3) is connected to the electrode socket (701) by a lead and a plug.
5. The vagal stimulation device for weight loss according to claim 4, further comprising a power source that powers the controller (1) and the display screen (8).
6. The vagal nerve stimulation device for weight loss according to claim 5, wherein a charging jack (702) is further provided on the housing (7), the charging jack (702) being connected with the power source.
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CN110339450A (en) * 2019-07-17 2019-10-18 南昌大学第一附属医院 It is a kind of to promote therapeutic equipment of waking up through nervus auricularis vagi electro photoluminescence stupor
CN110559554A (en) * 2019-08-22 2019-12-13 西安八水健康科技有限公司 Electrical stimulation device fusing transcranial electrical stimulation and vagus nerve stimulation
CN110585593A (en) * 2019-08-22 2019-12-20 西安八水健康科技有限公司 Multi-mode memory consolidation stimulation equipment based on electroencephalogram signal feedback
CN110496309A (en) * 2019-08-22 2019-11-26 西安八水健康科技有限公司 A kind of respiration gate control vagal stimulation system and device
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