CN113453620B - 用于双重检测葡萄糖和乙醇的分析物传感器和感测方法 - Google Patents

用于双重检测葡萄糖和乙醇的分析物传感器和感测方法 Download PDF

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Publication number
CN113453620B
CN113453620B CN202080011184.5A CN202080011184A CN113453620B CN 113453620 B CN113453620 B CN 113453620B CN 202080011184 A CN202080011184 A CN 202080011184A CN 113453620 B CN113453620 B CN 113453620B
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ethanol
glucose
active region
membrane
responsive active
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CN113453620A (zh
Inventor
T·欧阳
B·J·费尔德曼
H·赵
L·N·德兰
S·奥贾
M·K·斯隆恩
A·库玛
N·基阿伊
M·R·洛夫
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Abbott Diabetes Care Inc
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Abbott Diabetes Care Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/16—Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state
    • A61B5/18—Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state for vehicle drivers or machine operators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4845—Toxicology, e.g. by detection of alcohol, drug or toxic products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B60—VEHICLES IN GENERAL
    • B60K—ARRANGEMENT OR MOUNTING OF PROPULSION UNITS OR OF TRANSMISSIONS IN VEHICLES; ARRANGEMENT OR MOUNTING OF PLURAL DIVERSE PRIME-MOVERS IN VEHICLES; AUXILIARY DRIVES FOR VEHICLES; INSTRUMENTATION OR DASHBOARDS FOR VEHICLES; ARRANGEMENTS IN CONNECTION WITH COOLING, AIR INTAKE, GAS EXHAUST OR FUEL SUPPLY OF PROPULSION UNITS IN VEHICLES
    • B60K28/00—Safety devices for propulsion-unit control, specially adapted for, or arranged in, vehicles, e.g. preventing fuel supply or ignition in the event of potentially dangerous conditions
    • B60K28/02—Safety devices for propulsion-unit control, specially adapted for, or arranged in, vehicles, e.g. preventing fuel supply or ignition in the event of potentially dangerous conditions responsive to conditions relating to the driver
    • B60K28/06—Safety devices for propulsion-unit control, specially adapted for, or arranged in, vehicles, e.g. preventing fuel supply or ignition in the event of potentially dangerous conditions responsive to conditions relating to the driver responsive to incapacity of driver
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    • B60K28/00—Safety devices for propulsion-unit control, specially adapted for, or arranged in, vehicles, e.g. preventing fuel supply or ignition in the event of potentially dangerous conditions
    • B60K28/02—Safety devices for propulsion-unit control, specially adapted for, or arranged in, vehicles, e.g. preventing fuel supply or ignition in the event of potentially dangerous conditions responsive to conditions relating to the driver
    • B60K28/06—Safety devices for propulsion-unit control, specially adapted for, or arranged in, vehicles, e.g. preventing fuel supply or ignition in the event of potentially dangerous conditions responsive to conditions relating to the driver responsive to incapacity of driver
    • B60K28/063—Safety devices for propulsion-unit control, specially adapted for, or arranged in, vehicles, e.g. preventing fuel supply or ignition in the event of potentially dangerous conditions responsive to conditions relating to the driver responsive to incapacity of driver preventing starting of vehicles
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B60K28/00—Safety devices for propulsion-unit control, specially adapted for, or arranged in, vehicles, e.g. preventing fuel supply or ignition in the event of potentially dangerous conditions
    • B60K28/02—Safety devices for propulsion-unit control, specially adapted for, or arranged in, vehicles, e.g. preventing fuel supply or ignition in the event of potentially dangerous conditions responsive to conditions relating to the driver
    • B60K28/06—Safety devices for propulsion-unit control, specially adapted for, or arranged in, vehicles, e.g. preventing fuel supply or ignition in the event of potentially dangerous conditions responsive to conditions relating to the driver responsive to incapacity of driver
    • B60K28/066—Safety devices for propulsion-unit control, specially adapted for, or arranged in, vehicles, e.g. preventing fuel supply or ignition in the event of potentially dangerous conditions responsive to conditions relating to the driver responsive to incapacity of driver actuating a signalling device
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/30—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving catalase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/98—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving alcohol, e.g. ethanol in breath
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B60—VEHICLES IN GENERAL
    • B60W—CONJOINT CONTROL OF VEHICLE SUB-UNITS OF DIFFERENT TYPE OR DIFFERENT FUNCTION; CONTROL SYSTEMS SPECIALLY ADAPTED FOR HYBRID VEHICLES; ROAD VEHICLE DRIVE CONTROL SYSTEMS FOR PURPOSES NOT RELATED TO THE CONTROL OF A PARTICULAR SUB-UNIT
    • B60W40/00—Estimation or calculation of non-directly measurable driving parameters for road vehicle drive control systems not related to the control of a particular sub unit, e.g. by using mathematical models
    • B60W40/08—Estimation or calculation of non-directly measurable driving parameters for road vehicle drive control systems not related to the control of a particular sub unit, e.g. by using mathematical models related to drivers or passengers
    • B60W2040/0818—Inactivity or incapacity of driver
    • B60W2040/0836—Inactivity or incapacity of driver due to alcohol
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B60—VEHICLES IN GENERAL
    • B60W—CONJOINT CONTROL OF VEHICLE SUB-UNITS OF DIFFERENT TYPE OR DIFFERENT FUNCTION; CONTROL SYSTEMS SPECIALLY ADAPTED FOR HYBRID VEHICLES; ROAD VEHICLE DRIVE CONTROL SYSTEMS FOR PURPOSES NOT RELATED TO THE CONTROL OF A PARTICULAR SUB-UNIT
    • B60W2540/00—Input parameters relating to occupants
    • B60W2540/24—Drug level, e.g. alcohol

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CN202080011184.5A 2019-01-28 2020-01-28 用于双重检测葡萄糖和乙醇的分析物传感器和感测方法 Active CN113453620B (zh)

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CN202410171780.XA CN118105070A (zh) 2019-01-28 2020-01-28 用于双重检测葡萄糖和乙醇的分析物传感器和感测方法

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US201962797566P 2019-01-28 2019-01-28
US62/797,566 2019-01-28
US201962884841P 2019-08-09 2019-08-09
US62/884,841 2019-08-09
PCT/US2020/015400 WO2020159981A1 (en) 2019-01-28 2020-01-28 Analyte sensors and sensing methods for dual detection of glucose and ethanol

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AU (3) AU2020216330B2 (cg-RX-API-DMAC7.html)
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Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4325222A3 (en) 2016-03-04 2024-05-01 Abbott Diabetes Care Inc. Nad(p)-dependent responsive enzymes, electrodes and sensors, and methods for making and using the same
EP4574038A3 (en) 2019-01-28 2025-08-27 Abbott Diabetes Care, Inc. Analyte sensors and sensing methods featuring dual detection of glucose and ketones
US12220235B2 (en) * 2019-01-28 2025-02-11 Abbott Diabetes Care Inc. Analyte sensors and sensing methods for dual detection of glucose and ethanol
AU2020214230B2 (en) 2019-01-28 2023-03-02 Abbott Diabetes Care Inc. Analyte sensors employing multiple enzymes and methods associated therewith
CN113518584B (zh) 2019-01-28 2024-11-08 美国雅培糖尿病护理公司 检测肌酐的分析物传感器和感测方法
JP7590439B2 (ja) 2020-01-03 2024-11-26 アボット ダイアベティス ケア インコーポレイテッド 複数被検物質を検出するためのセンサアレイシステムおよび方法
WO2021163378A1 (en) * 2020-02-11 2021-08-19 Life Patch International Devices, methods and systems related to wearable patch having blood alcohol content detector
US20230248271A1 (en) * 2020-06-10 2023-08-10 Abbott Diabetes Care Inc. Analyte sensors featuring one or more detection-facilitating enhancements
US12667286B2 (en) 2020-06-16 2026-06-30 Abbott Diabetes Care Inc. Analyte sensors featuring working electrode asperity planing for decreasing interferent signal
CA3182587A1 (en) 2020-07-08 2022-01-13 Stephen OJA Analyte sensors featuring enhancements for decreasing interferent signal
WO2022051889A1 (zh) * 2020-09-08 2022-03-17 三诺生物传感股份有限公司 提高电化学活性的氧化还原酶及含有该氧化还原酶的生物传感器
WO2022109008A1 (en) * 2020-11-18 2022-05-27 Cercacor Laboratories, Inc. Glucose sensors and methods of manufacturing
CN122182027A (zh) * 2020-12-15 2026-06-12 美国雅培糖尿病护理公司 基于nad(p)-依赖酶的传感器的nad(p)储库
CN116634940A (zh) * 2020-12-18 2023-08-22 美国雅培糖尿病护理公司 用于分析物检测的系统和方法
CN116897014A (zh) * 2020-12-23 2023-10-17 美国雅培糖尿病护理公司 连续型钾传感器及其使用方法
CN116897015A (zh) * 2020-12-23 2023-10-17 雅培糖尿病护理公司 具有减少的干扰物信号的分析物传感器和方法
US12097760B2 (en) * 2021-07-28 2024-09-24 Caterpillar Inc. Methods and systems for detecting a machine operator
US12632542B1 (en) * 2022-11-09 2026-05-19 Gen Digital, Inc. Systems and methods for detecting user incapacitated states for securing a mobile device against unintended use
WO2024145693A1 (en) 2022-12-30 2024-07-04 Abbott Diabetes Care Inc. Drug delivery compositions and methods of controlling drug delivery rates of subcutaneous sensors
EP4648680A2 (en) 2023-01-13 2025-11-19 Abbott Diabetes Care Inc. Biosensors with hydrophilic polyurethane membranes
AU2024211188A1 (en) 2023-01-25 2025-07-17 Abbott Diabetes Care Inc. Temperature-insensitive membranes for analyte sensors
JP2026520347A (ja) 2023-05-24 2026-06-23 アボット ダイアベティス ケア インコーポレイテッド 治療剤を分析物センサに取り込む方法
CN116735885B (zh) * 2023-05-25 2025-02-11 深圳硅基传感科技有限公司 多分析物监测传感器
US20250160702A1 (en) * 2023-10-04 2025-05-22 Abbott Diabetes Care Inc. Highly permeable membrane for biosensor
WO2026090426A1 (en) 2024-10-25 2026-04-30 Abbott Diabetes Care Inc. Electrochemical oxygen sensor

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792621A (en) * 1995-06-28 1998-08-11 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Fiber-optic chemiluminescent biosensors for monitoring aqueous alcohols and other water quality parameters
CN102149315A (zh) * 2008-09-11 2011-08-10 霍夫曼-拉罗奇有限公司 用于在活体内条件下测量分析物浓度的电极系统
CN102428364A (zh) * 2009-03-19 2012-04-25 爱德华兹生命科学公司 具有足够缓冲能力的膜系统
CN104487565A (zh) * 2012-05-03 2015-04-01 新加坡国立大学 一种通过非流失共价结合将酶结合于电极的无介体电化学葡萄糖检测过程及其产品
CN104684477A (zh) * 2012-09-28 2015-06-03 德克斯康公司 用于连续传感器的两性离子表面修饰
CN105307567A (zh) * 2013-01-22 2016-02-03 美敦力迷你迈德公司 使用脉冲电流电镀降低葡萄糖传感器氧响应并减少电极边缘生长

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264105A (en) 1989-08-02 1993-11-23 Gregg Brian A Enzyme electrodes
JP2900876B2 (ja) * 1996-03-19 1999-06-02 サンケン電気株式会社 表示装置の電源装置
US5696314A (en) 1996-07-12 1997-12-09 Chiron Diagnostics Corporation Multilayer enzyme electrode membranes and methods of making same
US6127138A (en) * 1997-04-24 2000-10-03 Kyoto Daiichi Kagaku Co., Ltd. Method of enzymatically measuring glycated protein
US6736957B1 (en) 1997-10-16 2004-05-18 Abbott Laboratories Biosensor electrode mediators for regeneration of cofactors and process for using
US6030827A (en) 1998-01-23 2000-02-29 I-Stat Corporation Microfabricated aperture-based sensor
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
US6241863B1 (en) 1998-04-27 2001-06-05 Harold G. Monbouquette Amperometric biosensors based on redox enzymes
US8268143B2 (en) 1999-11-15 2012-09-18 Abbott Diabetes Care Inc. Oxygen-effect free analyte sensor
US6605201B1 (en) 1999-11-15 2003-08-12 Therasense, Inc. Transition metal complexes with bidentate ligand having an imidazole ring and sensor constructed therewith
US8444834B2 (en) * 1999-11-15 2013-05-21 Abbott Diabetes Care Inc. Redox polymers for use in analyte monitoring
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US6875613B2 (en) * 2001-06-12 2005-04-05 Lifescan, Inc. Biological fluid constituent sampling and measurement devices and methods
US7501053B2 (en) 2002-10-23 2009-03-10 Abbott Laboratories Biosensor having improved hematocrit and oxygen biases
DE602004030549D1 (de) * 2003-04-04 2011-01-27 Lumidigm Inc Multispektralbiometriesensor
US7761130B2 (en) 2003-07-25 2010-07-20 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7460898B2 (en) 2003-12-05 2008-12-02 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
EP1685258A4 (en) 2003-10-29 2007-08-29 Agency Science Tech & Res BIOSENSOR
WO2005048834A1 (en) 2003-11-13 2005-06-02 Medtronic Minimed, Inc. Long term analyte sensor array
DE602004029092D1 (de) 2003-12-05 2010-10-21 Dexcom Inc Kalibrationsmethoden für einen kontinuierlich arbeitenden analytsensor
JP4802842B2 (ja) 2006-04-24 2011-10-26 株式会社デンソー 健康管理支援装置及び健康管理システム
US7831287B2 (en) * 2006-10-04 2010-11-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8808515B2 (en) 2007-01-31 2014-08-19 Abbott Diabetes Care Inc. Heterocyclic nitrogen containing polymers coated analyte monitoring device and methods of use
WO2008157820A1 (en) 2007-06-21 2008-12-24 Abbott Diabetes Care, Inc. Health management devices and methods
MX2010003205A (es) 2007-09-24 2010-04-09 Bayer Healthcare Llc Sensores de prueba multi-region y multi-potenciales, metodos y sistemas.
WO2009105337A2 (en) 2008-02-20 2009-08-27 Dexcom, Inc. Continuous medicament sensor system for in vivo use
US8620398B2 (en) 2008-06-02 2013-12-31 Abbott Diabetes Care Inc. Reference electrodes having an extended lifetime for use in long term amperometric sensors
US8608922B2 (en) * 2008-11-07 2013-12-17 The University Of Connecticut Biosensor for continuous monitoring of metabolites and proteins and methods of manufacture thereof
FI3714788T3 (fi) 2009-02-26 2023-04-25 Abbott Diabetes Care Inc Parannettujen analyyttisensorien valmistusmenetelmä
US20100213057A1 (en) 2009-02-26 2010-08-26 Benjamin Feldman Self-Powered Analyte Sensor
JP5795584B2 (ja) 2009-08-31 2015-10-14 アボット ダイアベティス ケア インコーポレイテッドＡｂｂｏｔｔ Ｄｉａｂｅｔｅｓ Ｃａｒｅ Ｉｎｃ． 医療用装置
RU2606769C2 (ru) 2009-09-04 2017-01-10 Лайфскэн Скотлэнд Лимитед Способ и система измерения уровня глюкозы
WO2011037702A1 (en) 2009-09-24 2011-03-31 Fresenius Medical Care Holdings, Inc. Amperometric creatinine biosensor with immobilized enzyme-polymer composition and systems using same, and methods
US8545693B2 (en) 2009-09-29 2013-10-01 Lifescan Scotland Limited Analyte measurment method and system
WO2011053715A2 (en) 2009-10-30 2011-05-05 Edwards Lifesciences Corporation Analyte sensor layers and methods
US9402574B2 (en) 2010-06-25 2016-08-02 The University Of Connecticut Sensors for analyte detection and methods of manufacture thereof
ES2592175T3 (es) 2010-08-24 2016-11-28 Microchips Biotech, Inc. Dispositivo de biodetección implantable y métodos de uso del mismo
US9468402B2 (en) * 2010-12-01 2016-10-18 Pinnacle Technology, Inc. Tissue implantable microbiosensor
CN107961016B (zh) 2010-12-09 2021-06-15 雅培糖尿病护理股份有限公司 具有包括小型感测斑点的感测表面的分析物传感器
US8608921B2 (en) 2011-01-20 2013-12-17 Medtronic Minimed, Inc. Layered enzyme compositions for use with analyte sensors
US20140054171A1 (en) * 2012-02-21 2014-02-27 Abbott Diabetes Care Inc. Analyte Sensor Utilizing Oxygen as Oxidant
US8921061B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
US9344777B2 (en) 2012-12-20 2016-05-17 Abbott Diabetes Care Inc. Wireless communication authentication for medical monitoring device
US9487811B2 (en) 2013-03-15 2016-11-08 Abbott Point Of Care Inc. Biosensor structures for improved point of care testing and methods of manufacture thereof
US9562874B2 (en) 2013-03-15 2017-02-07 Abbott Point Of Care Inc. Biosensor with improved interference characteristics
DE202014011530U1 (de) 2013-12-27 2022-01-27 Abbott Diabetes Care, Inc. Systeme und Vorrichtungen zur Authentifizierung in einer Analytüberwachungsumgebung
WO2016065081A2 (en) * 2014-10-22 2016-04-28 Dexcom, Inc. User interfaces for continuous glucose monitoring
JP6584821B2 (ja) * 2015-04-30 2019-10-02 株式会社東芝 測定用セル、検出装置および分析装置
US10238346B2 (en) * 2015-09-25 2019-03-26 Sanmina Corporation System and method for a biosensor integrated in a vehicle
EP3156789B1 (en) * 2015-10-15 2024-01-03 ARKRAY, Inc. Biosensor
US10324058B2 (en) 2016-04-28 2019-06-18 Medtronic Minimed, Inc. In-situ chemistry stack for continuous glucose sensors
EP3531120A4 (en) 2016-10-24 2020-06-10 PHC Holdings Corporation OXIDATION AGENT FOR ELECTRONIC MEDIATOR
ES3074709T3 (es) 2017-06-30 2026-07-22 Abbott Diabetes Care Inc Procedimiento y aparato para la detección de analito utilizando un biosensor electroquímico
FI3668400T3 (fi) 2017-08-18 2023-08-29 Abbott Diabetes Care Inc Menetelmä analyyttianturien yksilölliseen kalibrointiin
DE102018209611A1 (de) * 2018-06-14 2019-12-19 RUHR-UNIVERSITäT BOCHUM Verfahren zur Entfernung von gelöstem Sauerstoff bei einem elektrochemischen Biosensor, der als Sensorenzym eine Oxidase verwendet
US11744492B2 (en) 2018-08-29 2023-09-05 Medtronic, Inc. Electrochemical sensor including multiple work electrodes and common reference electrode
CN113518584B (zh) 2019-01-28 2024-11-08 美国雅培糖尿病护理公司 检测肌酐的分析物传感器和感测方法
US12220235B2 (en) * 2019-01-28 2025-02-11 Abbott Diabetes Care Inc. Analyte sensors and sensing methods for dual detection of glucose and ethanol
AU2020214230B2 (en) 2019-01-28 2023-03-02 Abbott Diabetes Care Inc. Analyte sensors employing multiple enzymes and methods associated therewith
EP4574038A3 (en) 2019-01-28 2025-08-27 Abbott Diabetes Care, Inc. Analyte sensors and sensing methods featuring dual detection of glucose and ketones
EP3948249A4 (en) 2019-03-24 2023-11-22 Baldwa, Mehul BIOSENSOR FOR DETECTING ANALYTES IN A FLUID

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792621A (en) * 1995-06-28 1998-08-11 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Fiber-optic chemiluminescent biosensors for monitoring aqueous alcohols and other water quality parameters
CN102149315A (zh) * 2008-09-11 2011-08-10 霍夫曼-拉罗奇有限公司 用于在活体内条件下测量分析物浓度的电极系统
CN102428364A (zh) * 2009-03-19 2012-04-25 爱德华兹生命科学公司 具有足够缓冲能力的膜系统
CN104487565A (zh) * 2012-05-03 2015-04-01 新加坡国立大学 一种通过非流失共价结合将酶结合于电极的无介体电化学葡萄糖检测过程及其产品
CN104684477A (zh) * 2012-09-28 2015-06-03 德克斯康公司 用于连续传感器的两性离子表面修饰
CN105307567A (zh) * 2013-01-22 2016-02-03 美敦力迷你迈德公司 使用脉冲电流电镀降低葡萄糖传感器氧响应并减少电极边缘生长

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