CN113425807A - Ganoderma lucidum spore composite powder and preparation method and application thereof - Google Patents
Ganoderma lucidum spore composite powder and preparation method and application thereof Download PDFInfo
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- CN113425807A CN113425807A CN202110794368.XA CN202110794368A CN113425807A CN 113425807 A CN113425807 A CN 113425807A CN 202110794368 A CN202110794368 A CN 202110794368A CN 113425807 A CN113425807 A CN 113425807A
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- ganoderma lucidum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8984—Dendrobium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/148—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with compounds of unknown constitution, e.g. material from plants or animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention relates to the technical field of ganoderma lucidum spore powder, in particular to ganoderma lucidum spore composite powder and a preparation method and application thereof, and the preparation method comprises the following steps: (1) pulverizing and sieving Dendrobium officinale to obtain Dendrobium officinale powder; (2) adding the dendrobium officinale powder into an ethanol water solution for hot reflux extraction to obtain dendrobium officinale extract 0; (3) adding Ganoderma spore powder into herba Dendrobii extractive solution, and performing ultrasonic wall breaking to obtain wall-broken treatment solution; (4) drying the wall-broken treatment liquid. The invention combines dendrobium officinale and ganoderma lucidum spore powder, not only can enrich the effect, but also can play a role in protecting the easily oxidized components of the ganoderma lucidum spore powder. In addition, the invention also combines the two extraction methods, and can effectively control the cost.
Description
Technical Field
The invention relates to the technical field of ganoderma lucidum spore powder, and particularly relates to ganoderma lucidum spore composite powder and a preparation method and application thereof.
Background
The Ganoderma spore powder is tiny egg-shaped germ cells ejected from Ganoderma in Ganoderma Pleurotus in growth and maturation stage, is rich in nutrient components such as glycopeptide, sterol, triterpene and alkaloids, and has effects of regulating immunity and delaying aging. Each Ganoderma spore is only 4-6 μm, is living organism, has double wall structure, and is surrounded by hard chitin cellulose. The spore wall structure is very stable, the absorption rate of direct taking is only 10%, and the nutrient content is not fully utilized.
At present, the research on the wall breaking technology of ganoderma lucidum spore powder is more at home and abroad, and the summary mainly comprises: biological enzymolysis method, physical method, chemical method, and mechanical method. The biological enzymolysis method has complex treatment procedures, easily polluted products, large equipment investment and higher cost; the chemical wall-breaking method has low wall-breaking rate, the effective components of the pollen are damaged in the wall-breaking process, and the harmful residues in the product are high and difficult to remove. The wall breaking is carried out by a mechanical method, and the diameter of the ganoderma lucidum spore is very small and is only 5-7 μm. For ordinary crushing machines, such particle size is the minimum limit size of crushing, and thus the wall breaking effect is not ideal. The ganoderma lucidum spore powder is rich in unsaturated fatty acid and other components which are easy to oxidize, so that the ganoderma lucidum spore powder is slightly improper to store after the traditional method is adopted for breaking the walls, the effective components can be oxidized and mildewed to generate odor, and the peroxide value and the acid value seriously exceed the standard.
Disclosure of Invention
In order to overcome the defects in the prior art, the invention aims to provide the ganoderma lucidum spore composite powder, and the preparation method and the application thereof, and the ganoderma lucidum spore composite powder has the advantages of high wall breaking efficiency, low cost and stable quality.
The purpose of the invention is realized by the following technical scheme:
a preparation method of ganoderma lucidum spore composite powder comprises the following steps:
(1) pulverizing and sieving Dendrobium officinale to obtain Dendrobium officinale powder;
(2) adding dendrobium officinale powder into an ethanol water solution for hot reflux extraction to obtain a dendrobium officinale extracting solution, wherein the mass ratio of the dendrobium officinale powder to the ethanol water solution is 1: 10-20 parts of;
(3) adding ganoderma lucidum spore powder into the dendrobium officinale extracting solution, and performing ultrasonic wall breaking to obtain a wall breaking treatment solution, wherein the mass ratio of the ganoderma lucidum spore powder to the dendrobium officinale extracting solution is 1: 10-15;
(4) drying the wall-broken treatment liquid to obtain the ganoderma lucidum spore composite powder.
Dendrobium officinale is sweet in nature and flavor, slightly cold, entering stomach and kidney meridians. The classic "Daojiao" listed Dendrobium officinale as the first of Jiuda Xiancao in Daojia classic, and famous physicians Huatuo, Zhang Zhongjing, Sun Simiao and Li Shizheng in the past were regarded as "herb of the celestial being in medicine". There are many records about the anti-aging effects of dendrobe in ancient medical book of losing weight, prolonging life, reinforcing deficiency and strengthening tendons and bones. Modern pharmacological research shows that the dendrobium officinale has the effects of resisting aging, resisting oxidation and tumors, reducing blood sugar, regulating body immunity and the like, and is widely applied to the aspects of hypoimmunity caused by chronic gastritis, diabetes, weak body after long-term illness, eye health care, auxiliary treatment of malignant tumors and the like.
The dendrobium officinale and the ganoderma lucidum spore powder are combined, so that the effect can be enriched, and the effect of protecting easily-oxidized components of the ganoderma lucidum spore powder can be achieved. In addition, the invention also combines the two extraction methods, and can effectively control the cost. The dendrobium officinale powder adopts a hot reflux extraction mode, and the ganoderma lucidum spore powder adopts an ultrasonic wall breaking mode, and the two modes have the common characteristic that the material-liquid ratio is higher, so that the energy consumption required by drying is higher. According to the invention, the dendrobium officinale extract is used as a solvent for ultrasonic wall breaking of the ganoderma lucidum spore powder, and compared with the single extraction, the dosage of the solvent can be reduced, so that the cost is effectively controlled, and the antioxidant ingredients in the dendrobium officinale extract can also effectively protect the ganoderma lucidum spore powder from being oxidized, so that the stability of the ganoderma lucidum spore composite powder is improved, and the product can be directly encapsulated or pressed into tablets, and can be stored for a long time under the condition of no pollution.
Wherein, in the step (1), the sieve is a sieve with 50 meshes.
Wherein, in the step (2), the ethanol volume fraction of the ethanol aqueous solution is 80-100%.
Wherein, in the step (2), the time of hot reflux extraction is 1-2 h.
Wherein in the step (3), the frequency of ultrasonic wall breaking is 30-40kHz, and the ultrasonic intensity is 2-10W/cm2。
Wherein, in the step (4), the drying method is spray drying, vacuum freeze drying or heating concentration drying. Preferably, the drying method is vacuum freeze drying, so that the medicinal components can be better protected.
A Ganoderma spore composite powder is prepared by the above method.
The application of the ganoderma lucidum spore composite powder comprises the following steps: the ganoderma lucidum spore composite powder is prepared into one of pills, powder, granules, tablets and capsules.
The invention has the beneficial effects that: the invention combines dendrobium officinale and ganoderma lucidum spore powder, not only can enrich the effect, but also can play a role in protecting the easily oxidized components of the ganoderma lucidum spore powder. In addition, the invention also combines the two extraction methods, and can effectively control the cost. The dendrobium officinale powder adopts a hot reflux extraction mode, and the ganoderma lucidum spore powder adopts an ultrasonic wall breaking mode, and the two modes have the common characteristic that the material-liquid ratio is higher, so that the energy consumption required by drying is higher. According to the invention, the dendrobium officinale extracting solution is used as a solvent for ultrasonic wall breaking of the ganoderma lucidum spore powder, and compared with the single extraction, the dosage of the solvent can be reduced, so that the cost is effectively controlled, and the antioxidant ingredients in the dendrobium officinale extracting solution can also effectively protect the ganoderma lucidum spore powder from being oxidized, so that the stability of the ganoderma lucidum spore composite powder is improved.
Detailed Description
The present invention will be further described with reference to the following examples for facilitating understanding of those skilled in the art, and the description of the embodiments is not intended to limit the present invention.
Example 1
A preparation method of ganoderma lucidum spore composite powder comprises the following steps:
(1) pulverizing and sieving Dendrobium officinale to obtain Dendrobium officinale powder;
(2) adding dendrobium officinale powder into an ethanol water solution for hot reflux extraction to obtain a dendrobium officinale extracting solution, wherein the mass ratio of the dendrobium officinale powder to the ethanol water solution is 1: 15;
(3) adding ganoderma lucidum spore powder into the dendrobium officinale extracting solution, and performing ultrasonic wall breaking to obtain a wall breaking treatment solution, wherein the mass ratio of the ganoderma lucidum spore powder to the dendrobium officinale extracting solution is 1: 12.5;
(4) drying the wall-broken treatment liquid to obtain the ganoderma lucidum spore composite powder.
Wherein, in the step (1), the sieve is a sieve with 50 meshes.
Wherein, in the step (2), the ethanol volume fraction of the ethanol aqueous solution is 90%.
Wherein, in the step (2), the time of hot reflux extraction is 1.5 h.
Wherein in the step (3), the frequency of ultrasonic wall breaking is 35kHz, and the ultrasonic intensity is 6W/cm2。
Wherein, in the step (4), the drying method is vacuum freeze drying.
Example 2
A preparation method of ganoderma lucidum spore composite powder comprises the following steps:
(1) pulverizing and sieving Dendrobium officinale to obtain Dendrobium officinale powder;
(2) adding dendrobium officinale powder into an ethanol water solution for hot reflux extraction to obtain a dendrobium officinale extracting solution, wherein the mass ratio of the dendrobium officinale powder to the ethanol water solution is 1: 10;
(3) adding ganoderma lucidum spore powder into the dendrobium officinale extracting solution, and performing ultrasonic wall breaking to obtain a wall breaking treatment solution, wherein the mass ratio of the ganoderma lucidum spore powder to the dendrobium officinale extracting solution is 1: 10;
(4) drying the wall-broken treatment liquid to obtain the ganoderma lucidum spore composite powder.
Wherein, in the step (1), the sieve is a sieve with 50 meshes.
Wherein, in the step (2), the ethanol volume fraction of the ethanol aqueous solution is 80%.
Wherein, in the step (2), the time of hot reflux extraction is 1 h.
Wherein in the step (3), the frequency of ultrasonic wall breaking is 30kHz, and the ultrasonic intensity is 2W/cm2。
Wherein, in the step (4), the drying method is spray drying.
Example 3
A preparation method of ganoderma lucidum spore composite powder comprises the following steps:
(1) pulverizing and sieving Dendrobium officinale to obtain Dendrobium officinale powder;
(2) adding dendrobium officinale powder into an ethanol water solution for hot reflux extraction to obtain a dendrobium officinale extracting solution, wherein the mass ratio of the dendrobium officinale powder to the ethanol water solution is 1: 20;
(3) adding ganoderma lucidum spore powder into the dendrobium officinale extracting solution, and performing ultrasonic wall breaking to obtain a wall breaking treatment solution, wherein the mass ratio of the ganoderma lucidum spore powder to the dendrobium officinale extracting solution is 1: 15;
(4) drying the wall-broken treatment liquid to obtain the ganoderma lucidum spore composite powder.
Wherein, in the step (1), the sieve is a sieve with 50 meshes.
Wherein, in the step (2), the ethanol volume fraction of the ethanol aqueous solution is 98%.
Wherein, in the step (2), the time of hot reflux extraction is 2 h.
Wherein in the step (3), the frequency of ultrasonic wall breaking is 40kHz, and the ultrasonic intensity is 10W/cm2。
Wherein, in the step (4), the drying method is spray drying, vacuum freeze drying or heating concentration drying.
Example 4
A preparation method of ganoderma lucidum spore composite powder comprises the following steps:
(1) pulverizing and sieving Dendrobium officinale to obtain Dendrobium officinale powder;
(2) adding dendrobium officinale powder into an ethanol water solution for hot reflux extraction to obtain a dendrobium officinale extracting solution, wherein the mass ratio of the dendrobium officinale powder to the ethanol water solution is 1: 12.5;
(3) adding ganoderma lucidum spore powder into the dendrobium officinale extracting solution, and performing ultrasonic wall breaking to obtain a wall breaking treatment solution, wherein the mass ratio of the ganoderma lucidum spore powder to the dendrobium officinale extracting solution is 1: 11.5;
(4) drying the wall-broken treatment liquid to obtain the ganoderma lucidum spore composite powder.
Wherein, in the step (1), the sieve is a sieve with 50 meshes.
Wherein, in the step (2), the ethanol volume fraction of the ethanol aqueous solution is 85%.
Wherein, in the step (2), the time of hot reflux extraction is 1.25 h.
Wherein in the step (3), the frequency of ultrasonic wall breaking is 33kHz, and the ultrasonic intensity is 4W/cm2。
In the step (4), the drying method is heating, concentrating and drying.
Example 5
A preparation method of ganoderma lucidum spore composite powder comprises the following steps:
(1) pulverizing and sieving Dendrobium officinale to obtain Dendrobium officinale powder;
(2) adding dendrobium officinale powder into an ethanol water solution for hot reflux extraction to obtain a dendrobium officinale extracting solution, wherein the mass ratio of the dendrobium officinale powder to the ethanol water solution is 1: 18;
(3) adding ganoderma lucidum spore powder into the dendrobium officinale extracting solution, and performing ultrasonic wall breaking to obtain a wall breaking treatment solution, wherein the mass ratio of the ganoderma lucidum spore powder to the dendrobium officinale extracting solution is 1: 14;
(4) drying the wall-broken treatment liquid to obtain the ganoderma lucidum spore composite powder.
Wherein, in the step (1), the sieve is a sieve with 50 meshes.
Wherein, in the step (2), the ethanol volume fraction of the ethanol aqueous solution is 95%.
Wherein, in the step (2), the time of hot reflux extraction is 1.75 h.
Wherein in the step (3), the frequency of ultrasonic wall breaking is 38kHz, and the ultrasonic intensity is 8W/cm2。
Wherein, in the step (4), the drying method is vacuum freeze drying.
The above-described embodiments are preferred implementations of the present invention, and the present invention may be implemented in other ways without departing from the spirit of the present invention.
Claims (8)
1. A preparation method of ganoderma lucidum spore composite powder is characterized by comprising the following steps: the method comprises the following steps:
(1) pulverizing and sieving Dendrobium officinale to obtain Dendrobium officinale powder;
(2) adding dendrobium officinale powder into an ethanol water solution for hot reflux extraction to obtain a dendrobium officinale extracting solution, wherein the mass ratio of the dendrobium officinale powder to the ethanol water solution is 1: 10-20 parts of;
(3) adding ganoderma lucidum spore powder into the dendrobium officinale extracting solution, and performing ultrasonic wall breaking to obtain a wall breaking treatment solution, wherein the mass ratio of the ganoderma lucidum spore powder to the dendrobium officinale extracting solution is 1: 10-15;
(4) drying the wall-broken treatment liquid to obtain the ganoderma lucidum spore composite powder.
2. The method for preparing ganoderma lucidum spore composite powder according to claim 1, wherein the method comprises the following steps: in the step (1), the sieve is a sieve with 50 meshes.
3. The method for preparing ganoderma lucidum spore composite powder according to claim 1, wherein the method comprises the following steps: in the step (2), the ethanol volume fraction of the ethanol aqueous solution is 80-100%.
4. The method for preparing ganoderma lucidum spore composite powder according to claim 1, wherein the method comprises the following steps: and (2) performing hot reflux extraction for 1-2 h.
5. The method for preparing the ganoderma lucidum spore composite powder according to claim 4, wherein the method comprises the following steps: in the step (3), the frequency of ultrasonic wall breaking is 30-40kHz, and the ultrasonic intensity is 2-10W/cm2。
6. The method for preparing the ganoderma lucidum spore composite powder according to claim 4, wherein the method comprises the following steps: in the step (4), the drying method is spray drying, vacuum freeze drying or heating concentration drying.
7. A ganoderma lucidum spore composite powder is characterized in that: the method for preparing the ganoderma lucidum spore composite powder of any one of claims 1 to 6.
8. The application of the ganoderma lucidum spore composite powder is characterized in that: the ganoderma lucidum spore composite powder of claim 7 is prepared into one of pills, powder, granules, tablets and capsules.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115350245A (en) * | 2022-09-23 | 2022-11-18 | 晨日药业(辽宁)有限责任公司 | Composition with function of delaying senescence and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102600213A (en) * | 2012-04-01 | 2012-07-25 | 重庆邮电大学 | Effective antioxidation method for ganoderma lucidum spore powder |
| CN112057560A (en) * | 2020-10-15 | 2020-12-11 | 广东粤微食用菌技术有限公司 | Ganoderma lucidum spore dendrobium nobile composition capable of enhancing immunity and preparation method and application thereof |
| CN112138031A (en) * | 2020-09-08 | 2020-12-29 | 广东都市菜族农业科技有限公司 | Preparation method and application of ganoderma lucidum spore powder extract containing ganoderma lucidum triterpene and ganoderma lucidum polysaccharide |
-
2021
- 2021-07-14 CN CN202110794368.XA patent/CN113425807A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102600213A (en) * | 2012-04-01 | 2012-07-25 | 重庆邮电大学 | Effective antioxidation method for ganoderma lucidum spore powder |
| CN112138031A (en) * | 2020-09-08 | 2020-12-29 | 广东都市菜族农业科技有限公司 | Preparation method and application of ganoderma lucidum spore powder extract containing ganoderma lucidum triterpene and ganoderma lucidum polysaccharide |
| CN112057560A (en) * | 2020-10-15 | 2020-12-11 | 广东粤微食用菌技术有限公司 | Ganoderma lucidum spore dendrobium nobile composition capable of enhancing immunity and preparation method and application thereof |
Non-Patent Citations (2)
| Title |
|---|
| 王珂珂等: ""铁皮石斛提取物的抗氧化活性研究"", 《绿色科技》 * |
| 黄琴等: ""铁皮石斛多酚和黄酮含量及与抗氧化活性的相关性"", 《应用与环境生物学报》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115350245A (en) * | 2022-09-23 | 2022-11-18 | 晨日药业(辽宁)有限责任公司 | Composition with function of delaying senescence and preparation method thereof |
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Application publication date: 20210924 |