CN113423404A - 一种黄嘌呤衍生物药物组合物及其制备方法 - Google Patents
一种黄嘌呤衍生物药物组合物及其制备方法 Download PDFInfo
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- CN113423404A CN113423404A CN202080013251.7A CN202080013251A CN113423404A CN 113423404 A CN113423404 A CN 113423404A CN 202080013251 A CN202080013251 A CN 202080013251A CN 113423404 A CN113423404 A CN 113423404A
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- xanthine derivative
- microcrystalline cellulose
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- 238000002360 preparation method Methods 0.000 title claims abstract description 50
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- 101000930822 Giardia intestinalis Dipeptidyl-peptidase 4 Proteins 0.000 claims abstract description 15
- 239000003814 drug Substances 0.000 claims abstract description 15
- 150000001875 compounds Chemical class 0.000 claims description 209
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 116
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims description 91
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Abstract
本发明提供了一种黄嘌呤衍生物药物组合物，具体而言，提供了一种黄嘌呤衍生物的药物组合物及其制备方法及其作为治疗药物，特别是作为治疗二肽基肽酶(DPP‑IV)抑制剂的用途。
Description
PCT国内申请，说明书已公开。
Claims (21)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| CN201911214594 | 2019-12-02 | ||
| CN2019112145945 | 2019-12-02 | ||
| PCT/CN2020/132825 WO2021109970A1 (zh) | 2019-12-02 | 2020-11-30 | 一种黄嘌呤衍生物药物组合物及其制备方法 |
Publications (2)
| Publication Number | Publication Date |
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| CN113423404A true CN113423404A (zh) | 2021-09-21 |
| CN113423404B CN113423404B (zh) | 2023-09-29 |
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| CN202080013251.7A Active CN113423404B (zh) | 2019-12-02 | 2020-11-30 | 一种黄嘌呤衍生物药物组合物及其制备方法 |
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| CN (1) | CN113423404B (zh) |
| WO (1) | WO2021109970A1 (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114401724A (zh) * | 2019-09-27 | 2022-04-26 | 深圳信立泰药业股份有限公司 | 一种降糖药物组合物 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1675212A (zh) * | 2002-08-21 | 2005-09-28 | 贝林格尔英格海姆法玛两合公司 | 8－[3－氨基－哌啶－1－基]－黄嘌呤,其制备方法及作为药物制剂的用途 |
| CN101437493A (zh) * | 2006-05-04 | 2009-05-20 | 贝林格尔.英格海姆国际有限公司 | 二肽基肽酶iv抑制剂制剂 |
| CN103509023A (zh) * | 2012-06-20 | 2014-01-15 | 成都苑东药业有限公司 | 黄嘌呤衍生物 |
| WO2014080384A1 (en) * | 2012-11-26 | 2014-05-30 | Ranbaxy Laboratories Limited | Pharmaceutical composition of linagliptin |
| CN109692164A (zh) * | 2017-10-20 | 2019-04-30 | 深圳信立泰药业股份有限公司 | 化合物a或其盐的药物组合物及其制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103936737B (zh) * | 2013-01-23 | 2016-09-14 | 成都苑东生物制药股份有限公司 | 黄嘌呤衍生物 |
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| CN114401724B (zh) * | 2019-09-27 | 2024-05-24 | 深圳信立泰药业股份有限公司 | 一种降糖药物组合物 |
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| WO2021109970A1 (zh) | 2021-06-10 |
| CN113423404B (zh) | 2023-09-29 |
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