CN113388454B - Fishbone meal zymolyte antibacterial cleaning effervescent tablet and preparation method thereof - Google Patents
Fishbone meal zymolyte antibacterial cleaning effervescent tablet and preparation method thereof Download PDFInfo
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- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/02—Anionic compounds
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- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/02—Inorganic compounds ; Elemental compounds
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- C11D3/124—Silicon containing, e.g. silica, silex, quartz or glass beads
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- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2075—Carboxylic acids-salts thereof
- C11D3/2079—Monocarboxylic acids-salts thereof
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- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
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- C11D3/2086—Hydroxy carboxylic acids-salts thereof
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- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/37—Polymers
- C11D3/3703—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- C11D3/3707—Polyethers, e.g. polyalkyleneoxides
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- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
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- C11D3/3945—Organic per-compounds
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- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
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Abstract
The invention discloses an antibacterial cleaning effervescent tablet containing fishbone powder zymolyte, and belongs to the technical field of antibacterial cleaning. The fishbone meal zymolyte clean antibacterial effervescent tablet comprises the following raw materials in parts by weight: 8-15 parts of fishbone powder zymolyte, 10-50 parts of effervescent agent, 10-15 parts of surfactant, 3238 parts of adhesive and 3262 parts of lubricant; the fishbone powder zymolyte is obtained by carrying out enzymolysis on fishbone powder. The fishbone powder enzymolysis product obtained by enzymolysis of fishbone powder is used as an antibacterial agent, and the prepared cleaning effervescent tablet has the characteristics of high decontamination efficiency, continuous antibiosis, safety, environmental protection and no stimulation. The fishbone meal zymolyte contains rich natural antibacterial peptide, and when the fishbone meal zymolyte is applied to an antibacterial cleaning product, the types of antibacterial cleaning agents are enriched, convenience is brought to daily life of people, reference is provided for deep processing and application of fish product processing byproducts, and waste of resources is reduced.
Description
Technical Field
The invention belongs to the technical field of antibacterial cleaning, and relates to a cleaning and antibacterial fishbone meal zymolyte antibacterial cleaning effervescent tablet for kitchenware.
Background
The liquid detergent is used as the most common kitchen cleaning article used in the family life of people, has the functions of efficiently removing oil stains and bacteria, and can realize effective cleaning and antibiosis on kitchen utensils. In recent years, with the improvement of the cleaning requirements of people, some novel cleaning agents are produced, and the cleaning effervescent tablet serving as a novel cleaning agent is convenient to store and transport compared with the traditional detergent, can be quickly disintegrated in a short time to form abundant foam, and greatly improves the product performance of the cleaning agent.
At present, chemical preservatives are bacteriostatic and bactericidal components of conventional detergents on the market, but the bacteriostatic agents have the defects of poor heat resistance, certain irritation to skin, easiness in decomposition to generate harmful substances, poor safety and the like, and can cause environmental pollution along with the discharge of sewage. Therefore, an environmentally friendly detergent with high cleaning and antibacterial effects, low irritation, and no residue is yet to be developed.
Chinese patent CN110885716A discloses an antibacterial detergent, which is prepared by adding nano-silver as an antibacterial agent and using a hemp leaf extract as an auxiliary material to stabilize the silver antibacterial agent, so that the antibacterial effect of the detergent is achieved. The addition of the hemp leaf extract makes up the defects of unstable property and easy agglomeration and discoloration of the silver antibacterial agent, but the extraction process is complex to operate, increases the process cost and the production requirement, and still has the problem that the traditional liquid detergent is inconvenient to transport and store.
Chinese patent CN107384619B discloses a cleaning effervescent tablet with pesticide residue removal and bacterium removal effects and a preparation method thereof, the cleaning effervescent tablet adopts a special wet granulation process, sodium percarbonate is preferably added as a bacterium removal agent, and bacteria are oxidized and removed by active oxygen generated in the dissolving process of the sodium percarbonate. The sodium percarbonate has the defects of relatively high dissolution speed in water and high oxygen release speed in the dissolution process, so that the cleaning effervescent tablet has the defects of poor degerming effect, short action time and incapability of continuously inhibiting bacteria.
Chinese patent CN108851091A discloses an antibacterial peptide protein effervescent tablet and a preparation method thereof, and particularly relates to a novel black soldier fly antibacterial peptide protein effervescent tablet. However, the antibacterial peptide selected from the raw materials of the patent is the hermetia illucens protein peptide, so that the yield is low, the cost is high, and the large-scale production is not suitable.
In the current fish processing industry, most of the by-products generated by the fish in the processing process are not utilized, which causes serious waste of resources. 5363 it is found in the research of Wu Linze that the tilapia leftovers can be enzymolyzed to obtain high-activity antibacterial peptide, which provides reference for the deep processing and utilization of fish by-products. In addition, liu Ming and the like adopt a hydrothermal reaction and an ion exchange method to prepare the cuttlefish bone-doped transformed hydroxyapatite by using cuttlefish bones as raw materials, and the results show that Zn-CBHA, ti-CBHA and TiZn-CBHA have good antibacterial performance on escherichia coli and staphylococcus aureus.
Disclosure of Invention
The invention aims to provide a fishbone powder zymolyte antibacterial cleaning effervescent tablet and a preparation method thereof. The antibacterial cleaning effervescent tablet adopts fishbone powder zymolyte as an antibacterial agent, has the characteristics of good antibacterial performance, high safety and long antibacterial duration, has wide raw material sources, simple production process, quick and efficient decontamination, safety, no stimulation, no residue and no pollution, is a novel environment-friendly antibacterial cleaning agent, and is suitable for large-scale production.
In order to achieve the purpose, the invention adopts the following technical scheme:
an antibacterial cleaning effervescent tablet of fishbone powder zymolyte comprises the following components in parts by weight: 20-50 parts of fishbone powder zymolyte, 10-50 parts of effervescent agent, 1-15 parts of surfactant, 1-15 parts of binder and 8978 parts of lubricant 1~5.
The effervescent agent comprises an acid source and an alkali source, wherein the alkali source comprises one of sodium carbonate and sodium percarbonate, and the acid source comprises one of citric acid and tartaric acid.
The surfactant is fatty alcohol-polyoxyethylene ether sodium sulfate.
The adhesive is at least one of polyethylene glycol 6000 (number average molecular weight) and polyethylene glycol 8000 (number average molecular weight).
The lubricant is one or more of superfine silica gel powder, microcrystalline cellulose and magnesium stearate.
A preparation method of an effervescent tablet for antibacterial cleaning of fishbone powder zymolyte comprises the following steps:
1) Grinding fishbone powder zymolyte into uniform powder, sieving with a 60-mesh sieve, and placing in a dry environment for later use;
2) Taking effervescent raw materials, respectively sieving with 80 mesh sieve, and placing in a dry environment for use;
3) Respectively sieving the lubricant and the surfactant with a 60-mesh sieve, and placing the sieved substances in a dry environment for later use;
4) Putting the materials in the step 1) -3) into a stirrer and uniformly mixing;
5) Putting the adhesive into the stirrer in the step 4), fully stirring for 15 minutes at the rotating speed of 120r/min, and standing for later use;
6) And (3) putting the material obtained in the step 5) into a high-pressure forming tablet machine, and pressing into tablets with different specifications to obtain the fishbone powder zymolyte antibacterial cleaning effervescent tablet.
The fishbone powder zymolyte in the step 1) is prepared by the following method:
1) Firstly, preparing a buffer solution with the pH value of 3.0, and subpackaging the buffer solution into 250 mL conical bottles;
2) Sequentially weighing fishbone powder and pepsin 0.5mL (3200U/mg) and adding into the buffer solution, placing in a constant temperature oscillator at 140 r/min and 37 ℃, and carrying out enzymolysis at 4 h;
3) After the enzymolysis is finished, putting the enzymolysis liquid into a water bath kettle at 100 ℃ for water bath for 5 min to inactivate the enzyme;
4) And after cooling, centrifuging the enzymolysis liquid, taking supernatant, and freeze-drying to obtain the fishbone powder zymolyte.
The invention has the beneficial effects that:
1. the fishbone powder zymolyte obtained by enzymolysis of fishbone powder has good inhibitory action on escherichia coli, bacillus subtilis and micrococcus luteus, has good heat resistance, storage resistance and ultraviolet irradiation resistance, and is a natural antibacterial agent capable of efficiently inhibiting bacteria. The fishbone meal antibacterial cleaning effervescent tablet is prepared by taking fishbone meal zymolyte as a main material of an antibacterial bactericide and matching with an effervescent agent, a lubricant, a surfactant and an adhesive, and the preparation method thereof greatly improves the antibacterial and bactericidal efficiency of the cleaning effervescent tablet.
2. The fish bone meal zymolyte antibacterial cleaning effervescent tablet provided by the invention has the characteristics of good antibacterial performance, high safety and long antibacterial duration, is simple in production process, convenient to use, low in cost, safe, non-irritant, free of residue and pollution, and is a novel environment-friendly antibacterial cleaning agent.
3. The invention applies the antibacterial property of the fish product processing by-product to the production application of the antibacterial cleaning agent, thereby not only improving the safety of the antibacterial cleaning agent and providing convenience for the daily life of people, but also avoiding the waste of resources.
Detailed Description
In order to fully understand the technical contents of the present invention, the technical solutions of the present invention will be further described and illustrated with reference to the following specific embodiments. The examples are given solely for the purpose of illustration and are not intended to limit the scope of the invention.
Example 1
An antibacterial cleaning effervescent tablet of fishbone powder zymolyte comprises the following components in percentage by weight: 30 parts of fishbone powder zymolyte, 15 parts of sodium carbonate and citric acid (the mass ratio is 1:1), 10 parts of fatty alcohol-polyoxyethylene ether sodium sulfate, 10 parts of polyethylene glycol and 3 parts of micro silica gel.
1) Firstly, preparing a buffer solution with the pH value of 3.0, and subpackaging the buffer solution into 250 mL conical flasks; sequentially weighing the fishbone powder and pepsin, adding the fishbone powder and the pepsin into the buffer solution, placing the mixture in a constant-temperature oscillator, and carrying out enzymolysis on 6 h at 37 ℃ at 140 r/min; after the enzymolysis is finished, putting the enzymolysis liquid into a water bath kettle at 100 ℃ for water bath for 5 min to inactivate the enzyme; and after cooling, centrifuging the enzymolysis liquid, taking supernatant, and freeze-drying to obtain the fishbone powder zymolyte.
2) Grinding 300g of fishbone powder zymolyte into uniform powder, sieving with a 60-mesh sieve, and placing in a dry environment for later use;
3) Taking 150g of sodium carbonate and 150g of citric acid, respectively sieving with a 80-mesh sieve, and placing in a dry environment for later use;
4) Taking 30g of micro silica gel powder and 100g of fatty alcohol-polyoxyethylene ether sodium sulfate, respectively sieving with a 60-mesh sieve, and placing in a dry environment for later use;
5) Putting the materials in the step 2) to the step 4) into a stirrer and uniformly mixing;
6) Putting 100g of polyethylene glycol into the stirrer in the step 5), fully stirring for 15 minutes at the rotating speed of 120r/min, and standing for later use;
7) And (3) putting the material obtained in the step 6) into a high-pressure forming tablet machine, and pressing into tablets with different specifications to obtain the fishbone powder zymolyte antibacterial cleaning effervescent tablet.
Example 2
An antibacterial cleaning effervescent tablet of fishbone powder zymolyte comprises the following components in percentage by weight: 50 parts of fishbone powder zymolyte, 15 parts of sodium percarbonate and tartaric acid (in a mass ratio of 1:1), 9 parts of fatty alcohol-polyoxyethylene ether sodium sulfate, 10 parts of polyethylene glycol and 5 parts of magnesium stearate.
1) Firstly, preparing a buffer solution with the pH value of 3.0, and subpackaging the buffer solution into 250 mL conical flasks; sequentially weighing the fishbone powder and pepsin, adding the fishbone powder and the pepsin into the buffer solution, placing the mixture in a constant-temperature oscillator, and carrying out enzymolysis on 6 h at 37 ℃ at 140 r/min; after the enzymolysis is finished, putting the enzymolysis liquid into a water bath kettle at 100 ℃ for water bath for 5 min to inactivate the enzyme; and after cooling, centrifuging the enzymolysis liquid, taking supernatant, and freeze-drying to obtain the fishbone powder zymolyte.
2) Grinding 400g of fishbone powder zymolyte into uniform powder, sieving with a 60-mesh sieve, and placing in a dry environment for later use;
3) Taking 150g of sodium percarbonate and 150g of tartaric acid, respectively sieving the sodium percarbonate and the tartaric acid by a sieve of 80 meshes, and placing the sodium percarbonate and the tartaric acid in a dry environment for later use;
4) Taking 50g of magnesium stearate and 90g of fatty alcohol-polyoxyethylene ether sodium sulfate, respectively sieving with a 60-mesh sieve, and placing in a dry environment for later use;
5) Putting the materials in the step 2) to the step 4) into a stirrer and uniformly mixing;
6) 100g of polyethylene glycol is put into the stirrer in the step 5), fully stirred for 15 minutes at the rotating speed of 120r/min, and placed for standby;
7) And (3) putting the material obtained in the step 6) into a high-pressure forming tablet machine, and pressing into tablets with different specifications to obtain the fishbone powder zymolyte antibacterial cleaning effervescent tablet.
Example 3
An antibacterial cleaning effervescent tablet of fishbone powder zymolyte comprises the following components in percentage by weight: 40 parts of fishbone powder zymolyte, 15 parts of sodium carbonate and citric acid (the mass ratio is 1:1), 10 parts of fatty alcohol-polyoxyethylene ether sodium sulfate, 5 parts of polyethylene glycol and 2 parts of micro-powder silica gel.
1) Firstly, preparing a buffer solution with the pH value of 3.0, and subpackaging the buffer solution into 250 mL conical flasks; then sequentially weighing fishbone powder and pepsin, adding the fishbone powder and the pepsin into the buffer solution, placing the mixture into a constant-temperature oscillator, and carrying out enzymolysis on the mixture at 37 ℃ for 6 h at 140 r/min; after the enzymolysis is finished, putting the enzymolysis liquid into a water bath kettle at 100 ℃ for water bath for 5 min to inactivate the enzyme; and after cooling, centrifuging the enzymolysis liquid, taking supernatant, and freeze-drying to obtain the fishbone powder zymolyte.
2) Grinding 500g of fishbone powder zymolyte into uniform powder, sieving with a 60-mesh sieve, and placing in a dry environment for later use;
3) Taking 150g of sodium carbonate and 150g of citric acid, respectively sieving with a 80-mesh sieve, and placing in a dry environment for later use;
4) Taking 20g of micro silica gel powder and 100g of fatty alcohol-polyoxyethylene ether sodium sulfate, respectively sieving with a 60-mesh sieve, and placing in a dry environment for later use;
5) Putting the materials in the step 2) -4) into a stirrer to be uniformly mixed;
6) Putting 50g of polyethylene glycol into the stirrer in the step 5), fully stirring for 15 minutes at the rotating speed of 120r/min, and standing for later use;
7) And (3) putting the material obtained in the step 6) into a high-pressure forming tablet machine, and pressing into tablets with different specifications to obtain the fishbone powder zymolyte antibacterial cleaning effervescent tablet.
Comparative example 1
An antibacterial cleaning effervescent tablet comprises the following components in parts by weight: 15 parts of sodium carbonate and citric acid (mass ratio of 1:1), 10 parts of fatty alcohol-polyoxyethylene ether sodium sulfate, 10 parts of polyethylene glycol and 3 parts of micro-powder silica gel.
1) Taking 150g of sodium carbonate and 150g of citric acid, respectively sieving with a 80-mesh sieve, and placing in a dry environment for later use;
2) Taking 30g of micro silica gel powder and 100g of fatty alcohol-polyoxyethylene ether sodium sulfate, respectively sieving with a 60-mesh sieve, and placing in a dry environment for later use;
3) Putting the materials in the step 1) -2) into a stirrer and uniformly mixing;
4) Putting 100g of polyethylene glycol into the stirrer in the step 3), fully stirring for 15 minutes at the rotating speed of 120r/min, and standing for later use;
5) And (3) putting the materials in the step 4) into a high-pressure forming tablet machine, and pressing into tablets with different specifications to obtain the antibacterial cleaning effervescent tablet.
Comparative example 2
An antibacterial cleaning effervescent tablet comprises the following components in parts by weight: 15 parts of sodium carbonate and tartaric acid (mass ratio 1:1), 9 parts of fatty alcohol-polyoxyethylene ether sodium sulfate, 10 parts of polyethylene glycol and 5 parts of magnesium stearate.
1) Taking 150g of sodium percarbonate and 150g of tartaric acid, respectively sieving the sodium percarbonate and the tartaric acid by a sieve of 80 meshes, and placing the sodium percarbonate and the tartaric acid in a dry environment for later use;
2) Taking 50g of magnesium stearate and 90g of fatty alcohol-polyoxyethylene ether sodium sulfate, respectively sieving with a 60-mesh sieve, and placing in a dry environment for later use;
3) Putting the materials in the step 1) -2) into a stirrer and uniformly mixing;
4) Putting 100g of polyethylene glycol into the stirrer in the step 3), fully stirring for 15 minutes at the rotating speed of 120r/min, and standing for later use;
5) And (3) putting the material obtained in the step 4) into a high-pressure forming tablet machine, and pressing into tablets with different specifications, namely the antibacterial cleaning effervescent tablet.
Comparative example 3
An antibacterial cleaning effervescent tablet comprises the following components in parts by weight: 15 parts of sodium carbonate and citric acid (mass ratio 1:1), 10 parts of fatty alcohol-polyoxyethylene ether sodium sulfate, 5 parts of polyethylene glycol and 2 parts of micro silica gel.
1) Taking 150g of sodium carbonate and 150g of citric acid, respectively sieving with a 80-mesh sieve, and placing in a dry environment for later use;
2) Taking 20g of micro silica gel powder and 100g of fatty alcohol-polyoxyethylene ether sodium sulfate, respectively sieving with a 60-mesh sieve, and placing in a dry environment for later use;
3) Putting the materials in the step 1) -2) into a stirrer and uniformly mixing;
4) Putting 50g of polyethylene glycol into the stirrer in the step 3), fully stirring for 15 minutes at the rotating speed of 120r/min, and standing for later use;
5) And (5) putting the materials in the step 4) into a high-pressure forming tablet press, and pressing into tablets with different specifications to obtain the antibacterial cleaning effervescent tablet.
Detection method
1. Determination of disintegration time
The effervescent tablet is prepared by taking 1 effervescent tablet prepared in example 1, putting the effervescent tablet into a 500ml beaker (containing 200ml of water with the temperature of 25 ℃), starting timing when bubbles are generated, and stopping timing when gas around the tablet or the fragments stops escaping, namely the disintegration time of the effervescent tablet. The tablets should be dissolved or dispersed in water without agglomerated particles remaining.
TABLE 1 fishbone powder anti-bacterial cleaning effervescent tablet disintegration time
2. Evaluation of detergency
The cleaning effervescent tablets prepared in example 1~3 and comparative examples 1 to 3 were tested for detergency according to "method 1, oil removal rate method" in appendix B of the national standard GB/T9985-2000 "hand dishwashing detergent", and the test results are shown in Table 2 below.
Table 2 detergency test results (%)
Note: standard dishwashing detergents are formulated as described in appendix B1.4.3 of GB/9985-2000 "hand dishwashing detergents".
As can be seen from the above table, the detergency of the bacteriostatic cleaning effervescent tablets prepared in the example 1~3 and the comparative example of the invention is obviously higher than that of the national standard dish washing detergent.
3. Evaluation of bacteriostatic Effect
1. Experimental methods
The suspension quantitative sterilization test is adopted, and the test bacteria are staphylococcus aureus (ATCC 6538), escherichia coli (8099) and candida albicans (ATCC 10231). The three strains are respectively prepared into experimental bacterial suspensions according to the disinfection technical specification, and the concentration is 106 cfu/ml-108 cfu/ml.
(1) Respectively preparing the fishbone powder antibacterial cleaning effervescent tablets of the embodiments 1, 2 and 3 into 25mg/ml effervescent tablet water solution; the fish bone meal enzymatic hydrolysate of example 1~3 was removed to prepare a clean effervescent tablet, which was dissolved in water to prepare a 25mg/ml aqueous solution as a comparative example.
(2) Taking a sterilized test tube, taking 4.0ml of the fishbone powder antibacterial cleaning effervescent tablet solution obtained in each example into the test tube, respectively adding 0.1ml of test bacterial suspension, uniformly mixing, placing in a water bath at 20 ℃ for constant temperature, and acting for a specified time. 0.5ml of the sample solution is taken out and added into a 4.5ml neutralizing agent test tube, and the mixture is uniformly mixed. Neutralizing for 10min, taking bacterial liquid in each test tube, counting viable bacteria, and calculating killing logarithm value according to the following formula:
log Kill (KL) = log of mean viable bacteria concentration of control group (No) -log of viable bacteria concentration of test group (Nx)
2. Results of the experiment
The test results are shown in table 3. The test was repeated at least 3 times.
TABLE 3 quantitative bactericidal test results of fishbone powder antibacterial cleaning effervescent tablet suspension
As can be seen from the data in Table 3, the sterilizing effect of the fish bone powder antibacterial cleaning effervescent tablet in the embodiment of the invention is greatly improved compared with that of the cleaning effervescent tablet without adding the fish bone powder zymolyte in the comparative example, and the sterilizing rate of Escherichia coli in the embodiment 3 of the invention reaches 99.38%, which shows that the adding of the fish bone powder zymolyte can effectively improve the antibacterial performance of the cleaning effervescent tablet, has high-efficiency inhibition on Escherichia coli, and can be used for cleaning kitchen utensils.
The above description is only a preferred embodiment of the present invention, and all equivalent changes and modifications made in accordance with the claims of the present invention should be covered by the present invention.
Claims (3)
1. An antibacterial cleaning effervescent tablet of fishbone powder zymolyte is characterized in that: the raw materials comprise the following components in parts by weight: 20-50 parts of fishbone powder zymolyte, 10-50 parts of effervescent agent, 1-15 parts of surfactant, 1-15 parts of adhesive and 8978 parts of lubricant zxft 8978;
the effervescent agent comprises an acid source and an alkali source, wherein the alkali source comprises one of sodium carbonate and sodium percarbonate, and the acid source comprises one of citric acid and tartaric acid;
the surfactant is fatty alcohol-polyoxyethylene ether sodium sulfate;
the adhesive is polyethylene glycol;
the lubricant is one or more of superfine silica gel powder, microcrystalline cellulose and magnesium stearate;
the fishbone powder zymolyte is prepared by the following method:
1) Firstly, preparing a buffer solution with the pH value of 3.0, and subpackaging the buffer solution into 250 mL conical flasks;
2) Sequentially weighing fishbone powder and pepsin with the enzyme specific activity of 3200U/mg and 0.5mL, adding the weighed materials into a buffer solution, and placing the buffer solution in a constant-temperature oscillator for enzymolysis;
3) After enzymolysis is finished, carrying out water bath on the enzymolysis liquid to inactivate the enzyme;
4) Centrifuging the enzymolysis liquid after cooling, and freeze-drying the supernatant to obtain fishbone powder zymolyte;
the enzymolysis conditions in the step 2) are as follows: 140 r/min,37 ℃, and performing enzymolysis on 6 h;
and 3) carrying out water bath for 5 min in a water bath kettle at the temperature of 100 ℃.
2. The preparation method of the fish bone meal zymolyte antibacterial cleaning effervescent tablet as claimed in claim 1, which is characterized in that: the method comprises the following steps:
1) Grinding fishbone powder zymolyte into uniform powder, sieving with a 60-mesh sieve, and placing in a dry environment for later use;
2) Taking effervescent raw materials, respectively sieving with 80 mesh sieve, and placing in a dry environment for use;
3) Respectively sieving the lubricant and the surfactant with a 60-mesh sieve, and placing the sieved substances in a dry environment for later use;
4) Putting the materials in the step 1) -3) into a stirrer and uniformly mixing;
5) Putting the adhesive into the stirrer in the step 4), stirring and standing for later use;
6) And (3) putting the material obtained in the step 5) into a high-pressure forming tablet machine, and pressing into tablets with different specifications to obtain the fishbone powder zymolyte antibacterial cleaning effervescent tablet.
3. The method of claim 2, wherein: and 5) fully stirring for 15 minutes at the rotating speed of 120 r/min.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202110639737.8A CN113388454B (en) | 2021-06-09 | 2021-06-09 | Fishbone meal zymolyte antibacterial cleaning effervescent tablet and preparation method thereof |
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| CN202110639737.8A CN113388454B (en) | 2021-06-09 | 2021-06-09 | Fishbone meal zymolyte antibacterial cleaning effervescent tablet and preparation method thereof |
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| Publication Number | Publication Date |
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| CN113388454A CN113388454A (en) | 2021-09-14 |
| CN113388454B true CN113388454B (en) | 2022-12-13 |
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| US3769224A (en) * | 1968-05-31 | 1973-10-30 | Colgate Palmolive Co | Effervescent granules |
| US5480575A (en) * | 1992-12-03 | 1996-01-02 | Lever Brothers, Division Of Conopco, Inc. | Adjuncts dissolved in molecular solid solutions |
| EP1009793A1 (en) * | 1997-08-14 | 2000-06-21 | The Procter & Gamble Company | Enzymatic cleaning compositions |
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