CN113331815A - Multi-core radio frequency coil transceiving and ultrasonic array unit synchronous control device and method - Google Patents
Multi-core radio frequency coil transceiving and ultrasonic array unit synchronous control device and method Download PDFInfo
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- CN113331815A CN113331815A CN202010137706.8A CN202010137706A CN113331815A CN 113331815 A CN113331815 A CN 113331815A CN 202010137706 A CN202010137706 A CN 202010137706A CN 113331815 A CN113331815 A CN 113331815A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
Abstract
The invention discloses a multi-core radio frequency coil transceiving and ultrasonic array unit synchronous control device, which comprises a signal conditioning control module, a radio frequency coil transceiving switching module, a radio frequency output control module, an ultrasonic array output control module and an ultrasonic probe matching module. The device can realize the synchronous control of the receiving and sending of the multi-core coil and the real-time synchronous control of the ultrasonic dosage and the MRI imaging system, can provide more abundant and comprehensive judgment information, and simultaneously realizes the real-time and accurate control of the ultrasonic dosage.
Description
Technical Field
The invention relates to the medical field of magnetic resonance and ultrasonic technology, in particular to a device and a method for synchronously controlling the transceiving of a multi-core radio frequency coil and an ultrasonic array unit.
Background
Malignant tumor is a serious disease seriously harming human health, has complex and various types, and is one of the key scientific problems to be overcome urgently in the medical field. The ultrasonic ablation technology can effectively ablate a tumor focus area through high temperature generated by focused ultrasound, thereby realizing non-invasive treatment. However, the size of the focal region of the ultrasonic focus, the irradiation time, the temperature, and the like are too long, which may cause coagulation necrosis of the target region and may also cause irreversible damage to normal tissues, and thus, high control accuracy is required for both the ultrasonic dose and the therapeutic system control. The MRI technology can provide real-time visual monitoring information for monitoring the ultrasonic ablation treatment and system control by the characteristics of nondestructive detection, multi-parameter, temperature sensitivity, obvious soft tissue comparison and the like, and a feasible scheme is provided for solving the problems of the ultrasonic treatment dosage and system control.
Multiple needle pairs in practical conventional MRI and ultrasonic therapy system1H, the imaging and the subsequent analysis are carried out, the information provided by the H is limited, and the problems of tissue damage and the like caused by over-high ultrasonic dose can be caused. The multi-nuclear MRI imaging mode provides a new research method for solving the problems and simultaneously acquiring1H and other nuclear species, e.g.23Na、31P or19MRI images or spectra of F can provide more abundant information, and can be combined1The change condition of the tissue structure provided by the H image and the information such as metabolism, ion exchange and the like provided by other nuclides can provide more accurate measurement basis for judging the lesion area. In addition, considering the time-space synchronization of the acquired information, the MRI image acquisition of different nuclides needs to be performed synchronously and parallelly to ensure the accurate registration of the acquired information of different nuclides, and accordingly, the multi-core MRI radio frequency coil in the magnetic resonance system is required to have a parallel and synchronous control function. In addition, the dose control of ultrasound also needs to be controlled synchronously with the multi-core system to ensure real-time and accurate dose control, especially for the use of ultrasound arraysThe array treatment system further needs to control the operation modes of the different array units in real time so as to control the dose and the treatment area in real time. Accordingly, it is important to control the MRI system synchronously. However, conventional MRI and ultrasound therapy systems are two relatively independent systems and do not support synchronous control between MRI radio frequency coils and between ultrasound systems. In order to solve the problems in the MRI and ultrasonic medical system, the invention provides a device and a method for synchronously controlling the transceiving of a multi-core coil and an ultrasonic array unit.
Disclosure of Invention
The present invention provides a device and a method for synchronously controlling multi-core radio frequency transceiver and ultrasonic array unit, so as to solve the problems in the background art.
In order to achieve the purpose, the invention provides the following technical scheme:
a multi-core radio frequency coil transceiving and ultrasonic array unit synchronous control device comprises a signal conditioning control module, a radio frequency coil transceiving switching module, a radio frequency output control module, an ultrasonic array output control module and an ultrasonic probe matching module, wherein the signal conditioning control module converts a control signal from an MRI (magnetic resonance imaging) and ultrasonic therapy system into a voltage signal which can be identified by the radio frequency coil transceiving switching module and the ultrasonic array output control module and controls the state switching of the radio frequency coil transceiving switching module and the ultrasonic array output control module, the radio frequency coil transceiving switching module is used for converting the voltage control signal switched by the radio frequency transceiving into a current signal and driving the change of the switching of the radio frequency transceiving and the resonance state of a radio frequency coil, the radio frequency control output module is connected with the radio frequency transceiving switching module and the radio frequency transceiving coil and transmits the output current of the radio frequency transceiving switching module to the radio frequency transceiving coil, the ultrasonic array output control module is used for converting an ultrasonic output voltage control signal into a current control signal and controlling the on-off of ultrasonic output according to an input control signal, and the ultrasonic probe matching module is used for connecting the ultrasonic signal output by the ultrasonic array output control module and an ultrasonic probe and adjusting the load matching of the ultrasonic probe.
As a further technical scheme of the invention: the radio frequency coil receiving and transmitting switching module comprises a voltage-current amplifying circuit and a biasing circuit, the voltage-current amplifying circuit is used for converting a voltage signal from the signal conditioning and controlling unit into a current signal, the biasing circuit is used for outputting a control signal converted by the voltage-current amplifying circuit, controlling the resonance state of the radio frequency coil and the receiving and transmitting switching of the radio frequency signal, and simultaneously, controlling the radio frequency signal to be introduced into the voltage-current amplifying circuit.
As a further technical scheme of the invention: the ultrasonic array output control module comprises a voltage-current amplifying circuit, a bias circuit and an ultrasonic switch, wherein the voltage-current amplifying circuit is used for converting a voltage signal from the signal conditioning and control unit into a current signal, the bias circuit is used for outputting a control signal converted by the voltage-current amplifying circuit and controlling the closing state of the ultrasonic switch in the ultrasonic output channel, and the ultrasonic switch is used for controlling the output of the ultrasonic output channel.
As a further technical scheme of the invention: further comprising: and the radio frequency coil receiving-transmitting switching and radio frequency control output module corresponds to the multipath parallel different nuclides.
As a further technical scheme of the invention: further comprising: and the ultrasonic array unit output control and array unit matching module corresponds to the multi-path ultrasonic array.
A multi-core radio frequency coil transceiving and ultrasonic array unit synchronous control method comprises the following steps:
A. MRI imaging experiments;
B. ultrasonic focusing, namely positioning an ultrasonic focus area and position according to an MRI imaging experiment;
C. ultrasonic ablation, starting an ultrasonic array probe, enabling an ultrasonic output link to output an ultrasonic signal by an ultrasonic array unit output control module, and treating a focus area;
D. MRI real-time monitoring and evaluation;
E. real-time treatment control;
F. and judging the treatment of the target area.
As a further technical scheme of the invention: the step A is specifically as follows: the imaging nuclide and the imaging sequence are selected, the multi-core coil parallel transceiving module switches the output state in real time according to the time sequence and the control level, the transceiving of radio frequency signals is realized, the acquisition of the MRI image of the required nuclide is ensured, and the focus area is determined.
As a further technical scheme of the invention: the step D is specifically as follows: and carrying out multi-nuclide MRI imaging on the lesion region according to the set imaging sequence, and evaluating the treatment condition of the current region.
As a further technical scheme of the invention: the step E is specifically as follows: if the treatment of the current area is finished, the ultrasonic treatment is suspended, the output of the ultrasonic array is stopped, correspondingly, the ultrasonic array unit output control module prohibits the ultrasonic link from outputting ultrasonic signals according to the control signals output by the signal conditioning and control unit, and if the treatment of the current area is not finished, the ultrasonic dosage is continuously applied.
As a further technical scheme of the invention: the step F is specifically as follows: and B, judging whether a residual ablation region exists according to the MRI image, if an non-ablation region still exists, repeating the steps A to E, otherwise, stopping the ultrasonic ablation treatment, and controlling the output of the ultrasonic array unit to prohibit the ultrasonic link from outputting an ultrasonic signal.
Compared with the prior art, the invention has the beneficial effects that:
1) the multi-nuclide MRI imaging coils are synchronously controlled in parallel, MRI signals of different nuclides are simultaneously and parallelly acquired, synchronous registration of a target region can be achieved, and more comprehensive evaluation information is provided.
2) The multi-nuclide MRI imaging coil and the ultrasonic array are synchronously controlled, the ultrasonic thermotherapy can realize the synchronous monitoring of the diagnosis and treatment state, the enabling and the disabling of the ultrasonic array can be synchronously controlled, and the timeliness is high.
3) The ultrasonic array units are controlled in parallel, each subsequent array unit is reserved for parallel real-time control, the control precision is high, and the subsequent function expansion is facilitated.
Drawings
FIG. 1 is a schematic diagram of an MRI RF coil transceiving and ultrasonic synchronous parallel control device;
FIG. 2 is a schematic diagram of a multi-core parallel transceiving and ultrasonic array unit synchronous control device;
FIG. 3 is a diagram of a multi-core parallel transceiver module;
FIG. 4 is a schematic diagram of an ultrasonic array parallel output control module;
fig. 5 is a flowchart of a method for synchronously controlling the parallel transceiving and ultrasonic array units of the multi-core coil.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
referring to fig. 1, a synchronous control device for a multi-core rf coil transceiver and ultrasonic array unit includes a signal conditioning and control module, an rf coil transceiver switching module, an rf output control module, an ultrasonic array output control module, and an ultrasonic probe matching module.
And the signal conditioning and controlling module is used for converting the control signals from the MRI and ultrasonic therapy system into voltage signals compatible with the radio frequency coil transceiving switching module and the ultrasonic output controlling module.
And the radio frequency coil receiving and transmitting switching module is used for converting the received radio frequency signal receiving and transmitting and the radio frequency coil resonance state voltage control signal into a current signal and driving and changing the switching of the radio frequency receiving and transmitting switch and the resonance state of the radio frequency coil.
And the radio frequency control output module is used for inputting the control signals of the receiving and transmitting switching and the coil resonance state into the radio frequency coil.
And the ultrasonic output control module converts the received ultrasonic output state voltage control signal into a current control signal and is used for driving a radio frequency switch on the ultrasonic output channel to control the output state of the ultrasonic signal.
The ultrasonic probe matching module is used for adjusting the resonance matching of the ultrasonic probe and ensuring the maximum power efficient transmission of ultrasonic signals, and the ultrasonic probe matching function is formed by passive devices such as resistors, capacitors, inductors and other separating elements.
Example 2:
the difference from embodiment 1 is that, as shown in fig. 2, a multi-core radio frequency coil transceiving and ultrasound array unit synchronization control apparatus specifically includes:
and the signal conditioning and controlling module is used for converting control signals from the MRI and ultrasonic therapy system into voltage signals compatible with the multi-core parallel radio frequency coil transceiving switching module and the ultrasonic array output controlling module.
And the multi-nuclide parallel receiving and transmitting switching module converts the control voltage of the multi-nuclide parallel coil according to the MRI sequence time sequence and drives the switching of the resonance state of the multi-nuclide parallel coil or the switching of the receiving and transmitting of the radio frequency signal.
And outputting the parallel radio frequency control of the multi-core element, and transmitting the control signal of the parallel multi-core element transceiving coil to the multi-nuclide parallel synchronous transceiving coil.
The multi-path ultrasonic array unit controls output in parallel, converts voltage signals controlled by the output of the ultrasonic signals into current signals, drives a radio frequency switch on a multi-path parallel ultrasonic output channel, and controls the output of the ultrasonic signals.
And the multi-path parallel ultrasonic probe matching module is used for adjusting the load matching of the multi-path array ultrasonic probe and ensuring the maximum transmission of the parallel ultrasonic power of each path.
Example 3:
on the basis of embodiment 2, a schematic structural diagram of the multi-core parallel radio frequency control output module is shown in fig. 3, and includes:
the multi-path parallel V-I conversion circuit is used for realizing the current amplification of a control signal of the multi-core receiving and transmitting coil, wherein the V-I conversion circuit 1 corresponds to a nuclide 1, the V-I conversion circuit 2 corresponds to a nuclide 2, the V-I conversion circuit n corresponds to a nuclide n, and the conversion time sequence of each path is determined by a selected MRI pulse sequence.
The multi-path parallel bias circuit drives the multi-core radio frequency coil to switch the receiving and transmitting state or the resonance state, and controls the radio frequency signal to flow back to the V-I circuit, wherein the bias circuit 1 corresponds to the nuclide 1, the bias circuit 2 corresponds to the nuclide 2, and the bias circuit n corresponds to the nuclide n.
The bias circuit generally includes discrete components such as a choke inductor connected in series between the bias circuit and the rf coil, and a bypass capacitor connected in parallel between the choke inductor and the system ground.
Example 4:
on the basis of embodiment 3, a schematic structural diagram of a parallel control output module of a multi-path ultrasonic array unit is shown in fig. 4, and includes:
the multi-path parallel V-I conversion circuit is used for converting voltage signals controlled by ultrasonic output and generating current signals for driving the radio frequency switches of the corresponding ultrasonic output channels, wherein the V-I conversion circuit 1 corresponds to the ultrasonic array unit 1, the V-I conversion circuit 2 corresponds to the ultrasonic array unit 2, and the V-I conversion circuit n corresponds to the ultrasonic array unit n.
The multi-path parallel bias circuit drives a radio frequency switch in an output link in the multi-path ultrasonic array unit, controls the output of the multi-path parallel ultrasonic channels, and restrains the ultrasonic signals of the ultrasonic channels from flowing back to the V-I circuit, wherein the bias circuit 1 corresponds to the ultrasonic array unit 1, the bias circuit 2 corresponds to the ultrasonic array unit 2, and the bias circuit n corresponds to the ultrasonic array n.
And the multi-channel parallel radio frequency switch is used for changing the output of the ultrasonic signals of the multi-channel parallel ultrasonic channels, and the state of each channel is controlled by a corresponding bias circuit.
The control time sequence of the multi-path ultrasonic array unit is determined by the real-time MRI monitoring result, if the ultrasonic ablation is monitored to be completed, the multi-path parallel radio frequency switch is controlled to be switched off, otherwise, the switch is maintained to be in a closed state.
The invention also discloses a method for the parallel transceiving of the multi-core coil and the synchronous control of the ultrasonic array units, which comprises the following steps of:
A. the MRI experiment locates the focus, acquires the MRI image of multi-nuclide, determines the position of the focus, the multi-nuclide parallel transmit-receive switching module controls the transmit-receive state or resonance state switching of each nuclide transmit-receive coil during image acquisition, and the multi-channel parallel ultrasonic output control module prohibits the output of each channel.
B. And (4) ultrasonic focusing, namely adjusting the position of the ultrasonic probe according to the focal length of the ultrasonic array probe to ensure that the focal point of the ultrasonic array coincides with a focus area.
C. And ultrasonic ablation, wherein the output module is controlled by the multi-path ultrasonic array unit in parallel to enable the output of each ultrasonic channel to start ultrasonic treatment.
D. MRI real-time monitoring, collecting multi-nuclide parallel MRI images, a multi-nuclide parallel transmit-receive switching module controlling the transmit-receive state or resonance state switching of each nuclide transmit-receive coil, and a multi-channel parallel ultrasonic output control module enabling the output of each channel.
E. And (3) real-time treatment control, namely judging whether the treatment of the current local area is finished according to the MRI image, if so, stopping the treatment of the current area, and forbidding the output of each ultrasonic channel by the multi-channel ultrasonic array unit parallel control output module. Otherwise, the treatment of the current region is continued.
F. And C, diagnosis and treatment judgment, namely judging whether a residual region in the target region is not ablated according to the multi-nuclide MRI image, if so, repeating the steps A to E, otherwise, stopping the ultrasonic treatment, and correspondingly, controlling the output module to forbid the output of each ultrasonic channel by the multi-channel ultrasonic array unit in parallel.
Particularly, the receiving and transmitting control time sequence of the multiple paths of different nuclides is determined by the pulse sequence of the MRI control system, the output time and the control time sequence of the ultrasonic array unit are determined by the parallel MRI test results of the different nuclides, if the MRI test results judge ablation, the ultrasonic array output is stopped, and otherwise, the ultrasonic array output is kept.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (10)
1. The utility model provides a multinuclear radio frequency coil receiving and dispatching and supersound array unit synchro control device, includes signal conditioning control module, radio frequency coil receiving and dispatching switching module, radio frequency output control module, supersound array output control module and ultrasonic probe matching module, its characterized in that: the signal conditioning control module converts a control signal from an MRI and ultrasonic treatment system into a voltage signal which can be identified by the radio frequency coil transceiving switching module and the ultrasonic array output control module and controls the state switching of the radio frequency coil transceiving switching module and the ultrasonic array output control module, the radio frequency coil transceiving switching module is used for converting the voltage control signal switched by the radio frequency transceiving into a current signal and driving to change the switching of the radio frequency transceiving and the resonance state of the radio frequency coil, the radio frequency control output module is connected with the radio frequency transceiving switching module and the radio frequency transceiving coil and transmits the output current of the radio frequency transceiving switching module to the radio frequency transceiving coil, the ultrasonic array output control module is used for converting an ultrasonic output voltage control signal into a current control signal and simultaneously controlling the on-off of ultrasonic output according to the input control signal, and the ultrasonic probe matching module is used for connecting the ultrasonic signal output by the ultrasonic array and controlling the output of the ultrasonic probe, and is used to adjust the load matching of the ultrasound probe.
2. The device for synchronously controlling the transceiving of the multi-core radio frequency coil and the ultrasonic array unit according to claim 1, wherein the radio frequency coil transceiving switching module comprises a voltage-current amplifying circuit and a biasing circuit, the voltage-current amplifying circuit is used for converting a voltage signal from the signal conditioning and controlling unit into a current signal, the biasing circuit is used for outputting a control signal converted by the voltage-current amplifying circuit, controlling the resonant state of the radio frequency coil and the transceiving switching of the radio frequency signal, and simultaneously, throttling the radio frequency signal to be introduced into the voltage-current amplifying circuit.
3. The device of claim 1, wherein the ultrasound array output control module comprises a voltage-current amplifier circuit, a bias circuit and an ultrasound switch, the voltage-current amplifier circuit is configured to convert a voltage signal from the signal conditioning and control unit into a current signal, the bias circuit is configured to output a control signal converted by the voltage-current amplifier circuit and control a close state of the ultrasound switch in the ultrasound output channel, and the ultrasound switch is configured to control an output of the ultrasound output channel.
4. The device for synchronously controlling the transceiving of the multi-core radio frequency coil and the ultrasonic array unit according to claim 1, further comprising: and the radio frequency coil receiving-transmitting switching and radio frequency control output module corresponds to the multipath parallel different nuclides.
5. The device for synchronously controlling the transceiving of the multi-core radio frequency coil and the ultrasonic array unit according to claim 1, further comprising: and the ultrasonic array unit output control and array unit matching module corresponds to the multi-path ultrasonic array.
6. A multi-core radio frequency coil transceiving and ultrasonic array unit synchronous control method is characterized by comprising the following steps:
A. MRI imaging experiments;
B. ultrasonic focusing, namely positioning an ultrasonic focus area and position according to an MRI imaging experiment;
C. ultrasonic ablation, starting an ultrasonic array probe, enabling an ultrasonic output link to output an ultrasonic signal by an ultrasonic array unit output control module, and treating a focus area;
D. MRI real-time monitoring and evaluation;
E. real-time treatment control;
F. and judging the treatment of the target area.
7. The method for synchronously controlling the transceiving of the multi-core radio frequency coil and the ultrasonic array unit according to claim 6, wherein the step A specifically comprises: the imaging nuclide and the imaging sequence are selected, the multi-core coil parallel transceiving module switches the output state in real time according to the time sequence and the control level, the transceiving of radio frequency signals is realized, the acquisition of the MRI image of the required nuclide is ensured, and the focus area is determined.
8. The multi-core radio frequency coil transceiving and ultrasound array unit synchronization control method according to claim 6, wherein the step D specifically is: and carrying out multi-nuclide MRI imaging on the lesion region according to the set imaging sequence, and evaluating the treatment condition of the current region.
9. The method for synchronously controlling the transceiving of the multi-core radio frequency coil and the ultrasonic array unit according to claim 6, wherein the step E specifically comprises: if the treatment of the current area is finished, the ultrasonic treatment is suspended, the output of the ultrasonic array is stopped, correspondingly, the ultrasonic array unit output control module prohibits the ultrasonic link from outputting ultrasonic signals according to the control signals output by the signal conditioning and control unit, and if the treatment of the current area is not finished, the ultrasonic dosage is continuously applied.
10. The method for synchronously controlling the transceiving of the multi-core radio frequency coil and the ultrasonic array unit according to claim 6, wherein the step F specifically comprises: and B, judging whether a residual ablation region exists according to the MRI image, if an non-ablation region still exists, repeating the steps A to E, otherwise, stopping the ultrasonic ablation treatment, and controlling the output of the ultrasonic array unit to prohibit the ultrasonic link from outputting an ultrasonic signal.
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