CN105607021A - Magnetic resonance spectrometer - Google Patents
Magnetic resonance spectrometer Download PDFInfo
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- CN105607021A CN105607021A CN201510973771.3A CN201510973771A CN105607021A CN 105607021 A CN105607021 A CN 105607021A CN 201510973771 A CN201510973771 A CN 201510973771A CN 105607021 A CN105607021 A CN 105607021A
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- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
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Abstract
The invention provides a magnetic resonance spectrometer, the spectrometer comprises: a scan and reconstruction computer and a control scanning element, wherein the control scanning element comprises a scan resonance engine, a digital excitation engine, a scan sequential control module and a digital signal processing module; the scan resonance engine is connected with the scan and reconstruction computer to generate a scan sequential control subevent, a digital excitation subevent and a digital signal processing subevent, the subevents are respectively sent to the digital excitation engine, the digital signal processing module and the scan sequential control module; the digital excitation engine is connected with a gradient amplifier and a radio-frequency amplifier to generate a gradient waveform signal and a radio-frequency waveform signal; the digital signal processing module is separately connected with a digital radio-frequency receiving unit and the scan and reconstruction computer to receive a magnetic resonance imaging signal and transmit the signal to the scan and reconstruction computer for image reconstruction. The magnetic resonance spectrometer provided by the invention improves the magnetic resonance image quality.
Description
Technical field
The application relates to Medical Devices technology, particularly a kind of nuclear magnetic resonance spectrometer.
Background technology
Magnetic resonance (magneticresonance, MR) is the perseverance of utilizing the magnet in magnetic resonance system to produceFixed-field, by the control to radio system and gradient system, excites and receives magnetic by radio systemResonance signal, and utilize gradient magnetic to excite choosing layer and space encoding to sample, possess sky to obtainBetween a kind of tomograph imaging method of positional information.
Nuclear magnetic resonance spectrometer is a kind of equipment using in MR imaging method, for generation of radio systemThe radio frequency waveform using, the gradient waveform that gradient system uses, and can receiving magnetic resonance signals. PhaseIn the technology of pass, spectrometer is normally placed on the centralized device in control room, waveform generation module, signalEach functional module such as receiver module conventionally all concentrated setting in same equipment, and incite somebody to action by cableSpectrometer is connected and carries out signal transmission with parts such as radio frequency amplifier, gradient amplifier, radio-frequency coils. ThisThe shortcoming of the spectrometer of structure is that the picture quality of magnetic resonance imaging is not good.
Summary of the invention
In view of this, the application provides a kind of nuclear magnetic resonance spectrometer, to improve the picture quality of magnetic resonance.
Particularly, the application is achieved by the following technical solution:
First aspect, provides a kind of nuclear magnetic resonance spectrometer, comprising:
Scanning and reconstructing computer, for generation of magnetic resonance imaging information;
Gated sweep unit, comprising: scanning resonance engine, digital actuation engine, scanning sequence control mouldPiece and digital signal processing module;
Described scanning resonance engine, is connected with reconstructing computer with described scanning, for receiving and resolve instituteState magnetic resonance imaging information, obtain scanning sequence control subevent, digital actuation engine subevent and numeralSignal is processed subevent; Described digital actuation engine subevent is sent to digital actuation engine, by numeralSignal is processed subevent and is sent to digital signal processing module, and described scanning sequence control subevent is sentTo scanning sequence control module;
Described digital actuation engine, is connected with gradient amplifier and radio frequency amplifier, for according to described numberWord incentives engine subevent generates gradient waveform signal and radio frequency waveform signal, by described gradient waveform signalBe sent to gradient amplifier, described radio frequency waveform signal is transferred to radio frequency amplifier;
Described digital signal processing module, respectively with digital RF receiving element and scanning and reconstructing computerConnect, for: receive described digital RF receiving element according to described Digital Signal Processing subevent and obtainMagnetic resonance imaging signal, and described magnetic resonance imaging signal is transferred to described scanning and reconstructing computerFor image reconstruction;
Described scanning sequence control module, is connected with digital actuation engine and digital signal processing module respectively,Be used for according to described scanning sequence control subevent respectively to digital actuation engine and digital signal processing moduleSend Event triggered clock, and connect magnet electronic unit, and transmit and penetrate between described magnet electronic unitFrequently coil control information, peripheral hardware and gate information.
The nuclear magnetic resonance spectrometer that the application provides, by adopting distributed spectrometer structure, makes in spectrometerEach functional part can be arranged apart, these functional parts interconnected by link, like thisFunctional parts different in magnetic resonance system can be arranged in to different positions, such as numeral being penetratedFrequently receiving element is arranged near radio-frequency coil, even digital RF receiving element can be arranged on to radio frequency lineIn circle, can reduce like this electrical noise in signal long-distance transmission, improve signal quality, thereby improveThe picture quality of magnetic resonance, implements also more flexible.
Brief description of the drawings
Fig. 1 is the structural representation of a kind of nuclear magnetic resonance spectrometer shown in the application's one exemplary embodiment;
Fig. 2 is the motion flow of the scanning resonance engine shown in the application's one exemplary embodiment;
Fig. 3 is the motion flow of the scanning sequence control module shown in the application's one exemplary embodiment;
Fig. 4 is the motion flow of the digital actuation engine shown in the application's one exemplary embodiment;
Fig. 5 is the motion flow of the multi-modal signal transmitting unit shown in the application's one exemplary embodiment;
Fig. 6 is the motion flow of the magnet electronic unit shown in the application's one exemplary embodiment;
Fig. 7 is the motion flow of the digital RF receiving element shown in the application's one exemplary embodiment;
Fig. 8 is the structure of the expanding digital rf receiver unit shown in the application's one exemplary embodiment;
Fig. 9 is the motion flow of the digital signal processing module shown in the application's one exemplary embodiment.
Detailed description of the invention
Here will at length describe exemplary embodiment, its sample table shows in the accompanying drawings. BelowWhen description relates to accompanying drawing, unless separately there is expression, the same numbers in different accompanying drawings represents same or analogousKey element. Embodiment described in following exemplary embodiment does not represent the institute consistent with the applicationThere is embodiment. On the contrary, they be only with as in appended claims, described in detail, the application oneThe example of the consistent apparatus and method in a little aspects.
The application provides a kind of nuclear magnetic resonance spectrometer, and this spectrometer has adopted distributed structural design, canReferring to the spectrometer structural representation of Fig. 1, comprising: scanning and reconstructing computer 11, scan control unit 12(this unit is digital scan control unit, and the signal producing is data signal), multi-modal signalTransmitting element 13 (this unit is optional existence, and follow-up example describes in detail), magnet electronic unit 14 andDigital RF receiving element 15. Wherein, scan control unit 12 can comprise: scanning resonance engine 121,Digital actuation engine 122, scanning sequence control module 123 and digital signal processing module 124.
Scanning resonance engine 121 is connected with reconstructing computer 11 with scanning, can receive scanning and rebuild meterThe magnetic resonance imaging information that calculation machine 11 sends, for example, scan event list and sweep parameter etc. Scanning altogetherThe engine 121 that shakes can also be resolved magnetic resonance imaging information, obtain respectively for control figure incentives engine 122,The digital actuation of scanning sequence control module 123 and digital signal processing module 124 these three module workEngine subevent, scanning sequence control subevent and Digital Signal Processing subevent, and by digital actuationEngine subevent is sent to digital actuation engine, and Digital Signal Processing subevent is sent to data signal placeReason module, is sent to scanning sequence control module by scanning sequence control subevent. And scanning resonance engine121, digital actuation engine 122, scanning sequence control module 123 and digital signal processing module 124 itBetween, can realize high speed data transfer by high-speed differential signal.
Digital actuation engine 122, can be connected with gradient amplifier 16 and radio frequency amplifier 17, forThe digital actuation engine subevent sending according to scanning resonance engine 121, generates gradient waveform signal and penetratesFrequently waveform signal, is sent to gradient amplifier 16 by gradient waveform signal, and radio frequency waveform signal is transferred toRadio frequency amplifier 17. Be that digital actuation engine 122 can be responsible for generating gradient and radiofrequency signal, by thisTwo signals can make the magnetostatic square of the proton in magnetic resonance imaging body depart from the axial of magnetostatic field. When stoppingOnly apply after radiofrequency signal, proton will return to normal spin states, and to produce deamplification be magnetic resonanceImaging signal, this signal can be received by digital RF receiving element 15, and transfers to Digital Signal ProcessingModule 124.
Digital signal processing module 124, is connected with digital RF receiving element 15, and connects scanning with heavyBuild computer, receiving after the magnetic resonance imaging signal of digital RF receiving element 15, can be by this magnetic altogetherThe imaging signal that shakes transfers to and scans with reconstructing computer 11 for image reconstruction.
Scanning sequence control module 123, respectively with digital actuation engine 122 and digital signal processing module124 connect, for believing to digital actuation engine 122 and numeral respectively according to scanning sequence control subeventNumber processing module 124 sends Event triggered clock, produces radio frequency waveforms and ladder for controlling this two modulesThe time of degree waveform. Scanning sequence control module 123 also connects magnet electronic unit 14, with magnet electronicsBetween unit 14, transmit radio-frequency coil control information and peripheral hardware and gate information, for example, can controlThe reiving/transmitting state of radio-frequency coil, can also obtain coil temperature, magnet running status etc.
The exemplified spectrometer of Fig. 1 in this example, be a distributed spectrometer structure, in spectrometerEach functional part can separate, such as, multi-modal signal transmitting unit 13, digital RF receiveUnit 15, magnet electronic unit 14, with scan control unit 12 are three parts of separating physically,These functional parts are interconnected by link. The benefit of this structure is, can be by magnetic resonanceIn system, different functional parts is arranged in different positions, such as can be by digital RF receiving element 15Arrange near radio-frequency coil, even digital RF receiving element 15 can be arranged in radio-frequency coil, thisSample can reduce the electrical noise in signal long-distance transmission, improves signal quality, implements also clevererLive. Magnet electronic unit 14 can be arranged between magnet, collects the equipment between magnet with nearest distanceStatus information, and to send control information to radio-frequency coil and peripheral hardware and gate in the shortest time.
In another example, referring to the example of Fig. 1, can between each funtion part of distributed spectrometerWith by band optical fiber link connection, for example, scan resonance engine 121 by band optical fiber link and sweepRetouch with reconstructing computer 11 and be connected, digital actuation engine 122, can pass through band optical fiber link and gradientAmplifier 16 is connected with radio frequency amplifier 17, and digital signal processing module 124, by band optical fiber chainRoad is connected with digital RF receiving element 15, and scans and reconstructing computer by band optical fiber link connection11, magnetic resonance imaging signal can be received by digital RF receiving element 15, and by band optical fiber linkTransfer to digital signal processing module 124, then calculate by band optical fiber link transmission to scanning and reconstructionMachine 11 is for image reconstruction. Scanning sequence control module 123 is also by band optical fiber link connection magnet electricitySubelement 14. This connected mode is the connection of high-speed figure formula, can improve the anti-interference of signal.The magnetic resonance imaging that is receiving Multi-channel radio-frequency coil 18 and produce such as, digital RF receiving element 15After signal, this signal can be transferred to scan control unit with digital signal form, can improve signalQuality after transmission.
In addition, the spectrometer structure of this example not only can improve signal transmission quality, can also improve signalThe speed of processing, referring to the structure of Fig. 1 signal, in scan control unit 12, scanning resonance engine121 and digital signal processing module 124, can be respectively by different band optical fiber link connection scanning withReconstructing computer 11, such as, scanning resonance engine 121 by band optical fiber link 19 connect scanning withReconstructing computer 11, digital signal processing module 124 connects scanning with heavy by band optical fiber link 20Build computer 11, so just make scan control bus and receive data/address bus independently, can pass through broadbandOptical fiber link 19 transmits the coherent signal of scan control, and receive by 20 transmission of band optical fiber linkMagnetic resonance imaging signal, realizes the parallel processing of two aspects, accelerates conversion speed. And, thisKind structure is also beneficial to and realizes real time scan, and scan control unit can receive scanning and reconstructing computer in real timeThe 11 magnetic resonance information that send, and resolve the control that this information produces and receives for the signal of magnetic resonance.
The work of following each functional module to this nuclear magnetic resonance spectrometer respectively and realize principle and describe:
Scanning and reconstructing computer
The scanning of example and reconstructing computer 11 in Fig. 1, can be for realizing establishment, the volume of scanning sequenceCollect and compiling, the example of carrying out scanning sequence obtains personalized scanning sequence, and this example refers to doctor canWith according to current being scanned individual feature and scanning needs, on the basis of general scanning sequence, establishDetermine some and be scanned individual sweep parameter in the time carrying out magnetic resonance imaging for this. Scanning sequence exploitation andScanning sequence exampleization environment can adopt graphic mode, program description mode or text input mode,Through the example of scanning sequence, final generate for the scan event list of particular subject scanning application andSweep parameter, this scan event list and sweep parameter can be called magnetic resonance imaging information.
Scanning can be passed through band optical fiber chain by scan event list and sweep parameter with reconstructing computer 11The scanning resonance engine 121 that reaches scan control unit 12 under road, this band optical fiber link connection is disposed atThe optical fiber link interface of scanning and reconstructing computer 11 internal slots. Scanning also can with reconstructing computer 11To receive the magnetic resonance imaging signal sending from the digital signal processing module 124 of scan control unit 12,And carry out image reconstruction in conjunction with scanning sequence exampleization parameter. Scanning can with the control logic of reconstructing computer 11To be not limited to above-mentioned part.
Scanning resonance engine
The execution flow process of scanning resonance engine 121 can be shown in Figure 2, and scanning resonance engine 121 canThe scan event list and the scanning that send to receive scanning and reconstructing computer 11 by band optical fiber linkParameter. Scanning resonance engine 121 can be according to scan event label information, to received scanning thingPart list and sweep parameter are resolved, and parse scanning sequence control subevent, digital actuation engineEvent and Digital Signal Processing subevent. And can define peace treaty to subevent according to sweep parameterBundle, produces scan event circulation undated parameter, is distributed to scanning sequence control module, digital actuation engineModule and digital signal processing module. As shown in Figure 2, digital actuation engine subevent is sent to digital sharpEncourage engine 122, scanning sequence control subevent is sent to scanning sequence control module 123, data signal placeReason subevent is sent to digital signal processing module 124.
Above-mentioned each subevent that scanning resonance engine 121 parses, for example: the sub-thing of digital actuation enginePart or Digital Signal Processing subevent, the action that can comprise SECO information and each operational module is believedBreath, wherein, SECO packets of information is containing each subevent initial time and duration of scanning, and action is believedBreath comprises modules required movement, produces and sends out such as the required movement-radio frequency of digital actuation engine 122Penetrate, gradient produce with send, the collection of the required movement-resonance signal of digital signal processing module 124 withProcess.
The sweep parameter that scanning resonance engine 121 parses, can include restriction and definition SECOWith the parameter of the action of each operational module, such as radio-frequency pulse amplitude, frequency and initial phase, RF pulse-to-pulseRush type of waveform and data waveform is counted, gradient waveform slope and rise time, signals collecting is counted and is adoptedCollection interval, and signals collecting time started and end time etc.
Scanning sequence control module 123 receives the timing information of whole sequence, and digital actuation engine 122 connectsReceive timing information and the action message relevant to waveform generation, digital signal processing module 124 receives and numberAccording to gathering relevant timing information and action message. The follow-up detailed description respectively of processing of these three modules.
In scanning process, scanning resonance engine 121 can receive scanning and reconstructing computer 11 in real timeThe renewal magnetic resonance imaging information sending, scan event is upgraded and sweep parameter renewal, and separates in real timeAnalyse and be dispensed to scanning sequence control module 123, digital actuation engine 122 and digital signal processing module 124In, the setting of change corresponding scanning subevent and parameter; Complete the condition of current subevent in all modulesUnder, proceed to the response processing of the subevent sequence of renewal, realize the control of scanning real-time.
Scanning sequence control module
The motion flow of scanning sequence control module 123 can be shown in Figure 3, can receive and resolveThe scanning sequence control subevent that scanning resonance engine 121 sends, the time shaft scanning of obtaining scanning sequenceAction message, and can receive peripheral hardware and the gate information that magnet electronic unit 14 gathers, this peripheral hardwareInformation comprises the status signal of the parts such as magnet, gradient coil and radio-frequency coil, and gate information for example canComprise the physiology such as ecg-gating and respiration gate control gate-control signal.
In conjunction with this peripheral hardware status signal and physiology gate-control signal with resolve that scanning sequence control subevent obtainsInformation, scanning sequence control module 123 can calculate radio-frequency pulse and produce axle, slice selective gradient axle, phaseClock is synchronously triggered in the subevent of position coding axle and frequency coding axle, i.e. Event triggered clock, and divide in real timeIssue digital actuation engine 122 and digital signal processing module 124, as the reference clock of spectrometer systemSource, is used for driving the operation of spectrometer unit module, makes each scanning subevent according to predetermined sweepingRetouch sequential and carry out omnidistance scanning. Each scanning motion synchronous triggering signal shown in Fig. 3 (for example, is penetratedFrequently pulse produces axle scanning motion synchronous triggering signal) be above-mentioned Event triggered clock.
Digital actuation engine
The motion flow of digital actuation engine 122 can be in conjunction with shown in Fig. 4, this digital actuation engine 122Can receive digital actuation engine subevent and the corresponding sweep parameter thereof of self-scanning resonance engine 121,And resolve this digital actuation engine subevent and sweep parameter, obtain scanning sequence radio-frequency pulse produce axle,The scanning motion information of slice selective gradient axle, phase code axle and frequency coding axle, having walked abreast, it is selected to haveThe generation of the radio-frequency pulse data signal of bandwidth, centre frequency, amplitude and initial phase, has selected ladderThe time-to-climb of spending, preemphasis time constant, climb altitude and the slice selective gradient axle of duration, phase place compileThe generation of code axle and the axial digital gradient waveform signal of frequency coding, and each TR (repetitionTime, repetition time) scan period phase code axle gradient waveform amplitude upgrade numerical value.
After this, digital actuation engine 122 is followed the radio frequency of inputting from scanning sequence control module 123Pulse produces axle scanning motion synchronous triggering signal, slice selective gradient axle scanning motion synchronous triggering signal, phaseThe sequential of position coding axle scanning motion synchronous triggering signal and frequency coding axle scanning motion synchronous triggering signal,According to scanning sequence list of thing order, parallel output digital RF pulse signal, digital slice selective gradient arteries and veinsRush signal, digit phase encode gradient pulse signal and numerical frequency encode gradient pulse signal, eachDuring TR, the scanning sequence control logic providing according to scanning sequence control module 123, completes magnetic altogetherThe excitation of the phenomenon of shaking and generation, and the coding of reading to resonance signal. Digital actuation engine 122 simultaneouslyReceive gradient eddy current correction result and calculate, and generate accordingly gradient eddy current high-order compensation data signal.
Multi-modal signal transmitting unit
This multi-modal signal transmitting unit 13 is optional existence in spectrometer, imported for analog signalGradient amplifier and radio frequency amplifier, the input of gradient amplifier and radio frequency amplifier and multi-modal letterThe output of number transmitting element 13 is connected, to obtain analog radio-frequency signal and simulation gradient signal, and multimodeState signal transmitting unit 13 is by the digital actuation engine of band optical fiber link and scan control unit 12122 realize broadband high-speed transfer of data, with transmission of digital gradient and RF excited waveform signal, pass throughBand optical fiber link receives gradient waveform signal and the radio frequency waveform signal that digital actuation engine 122 generates,And this gradient waveform signal and radio frequency waveform signal are carried out being sent to gradient amplifier and penetrating after digital-to-analogue conversionAudio amplifier. For the imported gradient amplifier of data signal and radio frequency amplifier, can save multi-modalSignal transmitting unit 13, the input of gradient amplifier and radio frequency amplifier can pass through band optical fiber linkOutput direct and digital actuation engine 122 is realized broadband high-speed transfer of data.
Shown in Figure 5, multi-modal signal transmitting unit 13 can by Digital Signals module 51,Many radio-frequency pulses analogue signal generating module 52, two gradient pulse analogue signal generating module 53 and high-orderShimming signal generator module 54 forms. Multi-modal signal transmitting unit 13 receives by High-speed Optical Fiber LinkThe digital stimulus signal being produced by the digital actuation engine 122 of scan control unit 12, then pass through numeralSignal controlling module 51 sorts out each road radio-frequency pulse, gradient pulse and shimming gradient waveform signal, is oneIndividual or multiple radio frequency amplifiers and one or more gradient amplifier provide input signal.
Every road RF pulse signal stream inputs to corresponding high-speed DAC digital to analog converter, low through radio frequencyGrass pass filter amplifying element, is amplified to 0dBmW amplitude by RF pulse signal, exports to correspondenceRadio frequency amplifier. Described Mei road RF pulse signal can comprise multiple passages of different center frequencyRadio-frequency pulse output waveform signals, to support the output of multichannel RF pulse signal.
The gradient pulse signal stream that three tunnels have digital preemphasis inputs to respectively corresponding high-speed DAC numberWeighted-voltage D/A converter, adjusts transform part through signal separately and produces corresponding gradient pulse output signal,All export gradient source change-over switch (being gradient signal source change-over switch) to, will through gradient source change-over switchThree road gradient pulse signals are transferred to the gradient amplifier of appointment. By described gradient source change-over switch,Can support the input of many gradient amplifiers. For single gradient amplifier configuration scenario, the switching of gradient source is openedPass can arrange three-dimensional gradient pulse output 1 effectively or three-dimensional gradient pulse is exported 2 effective.
In addition, every road gradient eddy current high-order compensation data signal inputs to corresponding high-speed DAC digital-to-analogue and turnsParallel operation, exports corresponding gradient eddy current high-order compensation line to through signal condition link and power drive linkIn circle.
Magnet electronic unit
The motion flow of the magnet electronic unit 14 in spectrometer can be referring to Fig. 6, and this magnet electronic unit canTo comprise: CAN communication interface modules 61, PIN driver module 62, physiology gate interface module 63,Peripheral hardware state interface module 64.
CAN communication interface modules 61 can by High-speed Optical Fiber Link realize with scan control unit 12 inThe CAN bus communication of scanning sequence control module 123, this bus communication not only comprises radio-frequency coil controlInformation processed, under radio-frequency coil reiving/transmitting state control command and receiving coil passage switching control commandPass, also include but not limited to peripheral hardware state and the physiology gate waveforms such as gradient coil, radio-frequency coil, magnetUploading of signal.
PIN driver module 62 obtains radio-frequency coil reiving/transmitting state control life from CAN communication interface modules 61Order, drives the transmission state of radio-frequency sending coil and the switching of off resonance state, drives RF receiving coil groupIn each RF receiving coil realize the switching of accepting state and off resonance state.
Physiology gate interface module 63 completes ecg-gating signal, breath gate-control signal and periphery gate-control signalObtain and process, and realize carry out the transmission of physiology gate data to CAN communication interface modules 61.
Peripheral hardware state interface module 64 is for collecting the peripheral hardware states such as gradient coil, radio-frequency coil, magnet,Include but not limited to the access state of state of temperature, radio-frequency coil of gradient coil and running status, magnetRunning status, and to digital RF receiving element input radio frequency receive path gating control command.
Digital RF receiving element
Shown in Figure 7, the digital RF receiving element 15 in spectrometer can be according to through magnet electronic unitThe time sequence information of the 14 scanning sequence control modules 123 that transmit, opens and closes radio frequency reception channel, receives and locatesReason magnetic resonance imaging signal. Digital RF receiving element 15 can comprise Clock management module 71, dataGating and interface communication module 72 and at least one multichannel Receiver Module 73, wherein, Mei GeduoPassage Receiver Module 73 is connected with at least one Multi-channel radio-frequency coil, for receiving described multichannelThe magnetic resonance imaging signal that radio-frequency coil sends.
According to clinical scanning needs, can configure multiple digital RF receiving elements 15, form digital RFReceiving element group, realizes and mates interconnected with multi-channel coil group. Digital RF receiving element 15 can be realizedThe expansion of radio frequency reception channel, the Digital Signal Processing mould in the quantity of its expansion and scan control unit 12The quantity that piece 124 is expanded can be corresponding, to ensure uploading of high-speed broadband band radio frequency reception data.For example, for the clinical practice that can support body scan pattern, can adopt expanding digital radio frequency reception listThe mode of unit, the Multi-channel radio-frequency coil group adopting with body scan pattern is corresponding, as Fig. 8 example.
Digital RF receiving element 15 can be placed near Multi-channel radio-frequency coil group, for receiving multichannelRadio frequency coil magnetic resonance signal, also can be assemblied in multichannel by each digital RF receiving element 15 and penetrateFrequently in each radio-frequency coil of coil groups, realize the reception of digitized magnetic resonance.
Clock management module 71 can be entered the system reference clock signal that comes from scan control unit 12Row quality optimization, Clock Managing Unit has the structure of twin-lock phase cascade, by the dither cycle of clock signalBe restricted within the scope of 100 femtoseconds, to improve the signal to noise ratio of digital-to-analogue conversion.
The collection of these peripheral hardware information of status signal of the parts such as magnet, gradient coil and radio-frequency coil andThe collection of the physiology such as ecg-gating and respiration gate control gate-control signal, can be directly by optical fiber link and magnetElectronic unit 14 is realized transfer of data, and via totally digitilized scan control unit 12, is uploaded to and sweepsRetouch and reconstructing computer 11. Multi-channel radio-frequency coil group connects magnet electronic unit 14 by radio-frequency cable,Obtain coil state changeover control signal.
Data strobe and interface communication module 72, realize with the CAN of magnet electronic unit 14 logical on the one handThe data communication of letter interface module 61, is responsible for Multi-channel radio-frequency coil type and abnormal state information transmissionGive magnet electronic unit 14, receive from the CAN communication interface modules 61 of magnet electronic unit 14About carrying out passage gating and signal condition based on different scanning pattern in multichannel radiofrequency signal conditioning linkControl signal; The number of the digital signal processing module 124 of realization and scan control unit 12 on the other handAccording to communication, be responsible for to Multi-channel radio-frequency coil output impedance coupling and frequency tuning controlled quentity controlled variable, receive numeralThe digital RF that Signal Pretreatment is exported receives signal.
Each multichannel Receiver Module 73 can comprise for described magnetic resonance imaging signal is carried outRadiofrequency signal conditioning module, analog-to-digital conversion module and the Signal Pretreatment module processed. As shown in Figure 7,Radiofrequency signal conditioning module is the multichannel radiofrequency signal conditioning in Fig. 7, and analog-to-digital conversion module is A/D mouldNumber conversion group, Signal Pretreatment module is multichannel digital signal preprocessing part. Wherein, multichannel is penetratedFrequently signal condition module is made up of multiple radio frequency reception channel, can receive one or more radio-frequency coils defeatedThe magnetic resonance signal going out, the magnetic resonance signal low noise controllable gain of each receive path that is used for having walked abreastAdjust and bandpass filtering treatment, and the radiofrequency signal such as necessary IF Modulation is processed operation; A/D modulusConversion group is made up of the A/D analog-to-digital conversion parts of counting respective amount with radio frequency reception channel, is used for having walked abreastBecome the direct of multichannel radiofrequency signal or intermediate frequency digital-to-analogue conversion operation; Multichannel digital signal pretreatment moduleFormed by the data signal pretreatment link of counting respective amount with radio frequency reception channel, be used for Parallel Implementation eachThe preliminary extraction operation of if sampling data after individual digital-to-analogue conversion, or the reflection frequency acquisition of Direct Sampling andPreliminary extraction operation, to reduce the transmission bandwidth of each radio frequency reception channel data signal.
Digital signal processing module
The motion flow of the digital signal processing module 124 in the scan control unit 12 of spectrometer can be referring toFig. 9, this digital signal processing module 124 can comprise: channel data sorting, Digital Signal Processing group,The parts such as data buffering group and data packaging and transfer of data.
Wherein, the data that channel data sorting is responsible for transmitting from digital RF receiving element, sort out eachThe reception data of passage, and be distributed in each digital signal processing channel of Digital Signal Processing group. NumberWord signal processed group comprises multiple digital signal processor for channels, under each channel data that is used for having walked abreastThe Digital Signal Processing operation of the magnetic resonance signals such as frequency-conversion processing and FFT conversion.
Data buffering group comprise with Digital Signal Processing group in digital signal processor for channel equal numberData buffer, the data buffer storage of the channel digital signal processing that is used for having walked abreast, to complete the bag of dataThe transmission of dress and data.
Data packaging has been used for to counting from this digital signal processing module and other with transfer of data linkThe data packaging of word signal processing module and data processing, with realize digital signal processed data to scanning withThe expansion of uploading and realize digital signal processing module of reconstructing computer.
The application's nuclear magnetic resonance spectrometer, by employing distributed spectrum instrument system as above, and systemEach functional module between all adopt band optical fibers transmission to carry out digital transmission with interconnected, improvedThe anti-interference of signal transmission, has improved the signal to noise ratio of radio frequency reception channel, and then can improve figure picture elementAmount; And, also take some measures that improve scan control real-time, improve the letter of scan controlNumber transmission speed, such as, by scan control bus with to receive data/address bus independent, support real-time sequenceScanning, each Receiver Module in digital RF receiving element is carried out independently signal condition and numeralSignal processing operations, can realize the radio frequency reception of larger bandwidth, has improved gradient waveform and preemphasis place thereofThe real-time of reason, has also improved the processing speed of signal; By utilizing multi-modal signal transmitting unit to ladderDegree amplifier and radio frequency amplifier output signal, make this spectrometer can support many radio frequency source transmittings and how terracedThe output of degree source; In addition, digital RF receiving element can also be expanded, and supports many receiving coils simultaneouslyThe whole body image scanning mode of access; This distributed spectrometer structure also more adapts to flexible design exploitation,Meet low High-Field whole body clinical scanning demand, can also improve the temporal resolution of scan control, raising is penetratedFrequently the purity of frequency spectrum of output. Through test, use the application's nuclear magnetic resonance spectrometer, scan control in real timeProperty and picture quality are all improved.
The foregoing is only the application's preferred embodiment, not in order to limit the application, all at thisWithin the spirit and principle of application, any amendment of making, be equal to replacement, improvement etc., all should be included inWithin the scope of the application's protection.
Claims (10)
1. a nuclear magnetic resonance spectrometer, is characterized in that, described nuclear magnetic resonance spectrometer comprises:
Scanning and reconstructing computer, for generation of magnetic resonance imaging information;
Gated sweep unit, comprising: scanning resonance engine, digital actuation engine, scanning sequence control mouldPiece and digital signal processing module;
Described scanning resonance engine, is connected with reconstructing computer with described scanning, for receiving and resolve instituteState magnetic resonance imaging information, obtain scanning sequence control subevent, digital actuation engine subevent and numeralSignal is processed subevent; Described digital actuation engine subevent is sent to digital actuation engine, by numeralSignal is processed subevent and is sent to digital signal processing module, and described scanning sequence control subevent is sentTo scanning sequence control module;
Described digital actuation engine, is connected with gradient amplifier and radio frequency amplifier, for according to described numberWord incentives engine subevent generates gradient waveform signal and radio frequency waveform signal, by described gradient waveform signalBe sent to gradient amplifier, described radio frequency waveform signal is transferred to radio frequency amplifier;
Described digital signal processing module, respectively with digital RF receiving element and scanning and reconstructing computerConnect, for: receive described digital RF receiving element according to described Digital Signal Processing subevent and obtainMagnetic resonance imaging signal, and described magnetic resonance imaging signal is transferred to described scanning and reconstructing computerFor image reconstruction;
Described scanning sequence control module, is connected with digital actuation engine and digital signal processing module respectively,Be used for according to described scanning sequence control subevent respectively to digital actuation engine and digital signal processing moduleSend Event triggered clock, and connect magnet electronic unit, and transmit and penetrate between described magnet electronic unitFrequently coil control information, peripheral hardware and gate information.
2. nuclear magnetic resonance spectrometer according to claim 1, is characterized in that,
Described scanning resonance engine is connected with reconstructing computer with described scanning by wideband link; Described numberWord incentives engine is connected with gradient amplifier and radio frequency amplifier by wideband link; Described data signal placeReason module is connected with digital RF receiving element by wideband link, and by wideband link connect scan andReconstructing computer; Described scanning sequence control module connects magnet electronic unit by wideband link.
3. nuclear magnetic resonance spectrometer according to claim 2, is characterized in that,
Described scanning resonance engine and digital signal processing module, respectively by different wideband link and instituteStating scanning is connected with reconstructing computer.
4. nuclear magnetic resonance spectrometer according to claim 1, is characterized in that,
Described scanning resonance engine, also for: receive in real time described scanning and rebuild meter in scanning processThe renewal magnetic resonance imaging information that calculation machine sends, and send out after upgrading magnetic resonance imaging information described in real time parsingDeliver to described digital actuation engine, scanning sequence control module and digital signal processing module.
5. nuclear magnetic resonance spectrometer according to claim 1, is characterized in that, described digital RF connectsReceive unit, comprising: multiple multichannel Receiver Modules;
Each described multichannel Receiver Module, is connected with at least one Multi-channel radio-frequency coil, forReceive the magnetic resonance imaging signal that described Multi-channel radio-frequency coil sends; And described multichannel radio frequency receivingPiece comprises radiofrequency signal conditioning module, the analog-to-digital conversion for described magnetic resonance imaging signal is processedModule and Signal Pretreatment module.
6. nuclear magnetic resonance spectrometer according to claim 5, is characterized in that, described nuclear magnetic resonance spectrometerComprise: multiple described digital RF receiving elements.
7. nuclear magnetic resonance spectrometer according to claim 5, is characterized in that, described nuclear magnetic resonance spectrometerComprise: multiple digital signal processing modules.
8. nuclear magnetic resonance spectrometer according to claim 5, is characterized in that, described digital RF connectsReceive unit, be assemblied in described Multi-channel radio-frequency coil.
9. nuclear magnetic resonance spectrometer according to claim 1, is characterized in that, defeated for analog signalThe gradient amplifier and the radio frequency amplifier that enter type, described nuclear magnetic resonance spectrometer also comprises: multi-modal signal sendsUnit; Described multi-modal signal transmitting unit, for receiving described digital actuation engine by wideband linkThe gradient waveform signal and the radio frequency waveform signal that generate, and by described gradient waveform signal and radio frequency waveform letterNumber carry out being sent to gradient amplifier and radio frequency amplifier after digital-to-analogue conversion.
10. nuclear magnetic resonance spectrometer according to claim 1, is characterized in that, described scanning resonanceBetween engine, digital actuation engine, scanning sequence control module and digital signal processing module, by heightSpeed differential signal is realized high speed data transfer.
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