CN113671428A - Distributed magnetic resonance spectrometer system and synchronization method - Google Patents
Distributed magnetic resonance spectrometer system and synchronization method Download PDFInfo
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- CN113671428A CN113671428A CN202110996997.0A CN202110996997A CN113671428A CN 113671428 A CN113671428 A CN 113671428A CN 202110996997 A CN202110996997 A CN 202110996997A CN 113671428 A CN113671428 A CN 113671428A
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- G—PHYSICS
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- G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
- G01R33/36—Electrical details, e.g. matching or coupling of the coil to the receiver
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- G—PHYSICS
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- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
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Abstract
The invention provides a distributed magnetic resonance spectrometer system and a synchronization method, which relate to the technical field of magnetic resonance, wherein the system comprises synchronous exchange equipment, execution equipment and data generation equipment; the data generation equipment is connected with the synchronous switching equipment and sends the generated data to the synchronous switching equipment; the synchronous switching equipment is used for sending a reference signal to the execution equipment through the first reference clock module; the execution device includes: the system comprises a radio frequency transmitting module, a radio frequency receiving module and a gradient waveform generating module; the synchronous exchange equipment is also used for realizing time sequence synchronization and data exchange among the radio frequency transmitting module, the radio frequency receiving module and the gradient waveform generating module based on the reference signal. The system solves the technical problems of large phase deviation and low image quality caused by the layout of the existing equipment, and achieves the technical effect of improving the stability of phase synchronization.
Description
Technical Field
The invention relates to the technical field of magnetic resonance, in particular to a distributed magnetic resonance spectrometer system and a synchronization method.
Background
The magnetic resonance signal is a weak voltage signal, so the transmission loss of the magnetic resonance signal, especially the magnetic resonance signal with high field, on the coaxial cable is large. And the transmission of the magnetic resonance signal on the coaxial cable can introduce extra noise, so that the requirement that the receiving equipment of the spectrometer is placed between the magnets exists, the magnetic resonance signal is converted into a digital signal between the magnets, and the problem of the transmission of the magnetic resonance signal is solved. The existing spectrometer can realize the layout of radio frequency receiving equipment between magnets through an optical fiber interface, but the working mode of the existing spectrometer still runs under the trigger of synchronous sequence pulses, specifically, a sequence host sends sequence data to memories of a gradient waveform generation module and a radio frequency emission module through a spectrometer network, and then converts the sequence data into a sequence waveform and outputs the waveform under the trigger of the sequence pulses.
The radio frequency receiving and the radio frequency transmitting of the spectrometer are phase coherent, when the composition units of the spectrometer are intensively arranged between devices, the phase coherence cannot be influenced due to short wiring, but if the radio frequency receiving of the spectrometer is arranged between magnets, the receiving phase and the transmitting phase of the spectrometer are greatly different. The existing spectrometer only simply arranges the radio frequency transceiver among magnets, and does not solve the phase problem caused by the enlarged path. With the development of the magnetic resonance technology, the number of receiving channels is increased, the number of receivers is increased, the phase is used as important information for imaging of the magnetic resonance system, and the deviation of the phase can bring about image artifacts, which seriously affects the quality of the image.
Disclosure of Invention
The invention aims to provide a distributed magnetic resonance spectrometer system and a synchronization method, so as to solve the technical problems of large phase deviation and low image quality caused by the layout of the magnetic resonance spectrometer system in the prior art.
In order to achieve the above purpose, the embodiment of the present invention adopts the following technical solutions:
in a first aspect, an embodiment of the present invention provides a distributed magnetic resonance spectrometer system, where the system includes: synchronous exchange equipment, execution equipment and data generation equipment; the data generating equipment is connected with the synchronous switching equipment and sends the generated data to the synchronous switching equipment; the synchronous switching equipment comprises a first reference clock module; the synchronous exchange equipment is connected with the execution equipment; the synchronous switching equipment is used for sending a reference signal to the execution equipment through the first reference clock module; the above-mentioned execution apparatus includes: the system comprises a radio frequency transmitting module, a radio frequency receiving module and a gradient waveform generating module; the synchronous exchange equipment is also used for realizing time sequence synchronization and data exchange among the radio frequency transmitting module, the radio frequency receiving module and the gradient waveform generating module based on the reference signal.
In some possible embodiments, the spectrometer system further comprises: an image reconstruction module; the data generation device includes: a scanning module and a sequence module; the scanning module is respectively connected with the sequence module and the image reconstruction module; the scanning module is used for generating a scanning sequence based on input data and sending the scanning sequence to the sequence module; the sequence module and the image reconstruction module are respectively connected with the synchronous exchange equipment through a communication card unit; the sequence module is used for compiling the scanning sequence into a hardware parameter sequence and sending the hardware parameter sequence to the synchronous exchange equipment; the synchronous exchange equipment is used for sending the hardware parameter sequence to the execution equipment through a high-speed data interface based on the data type of the hardware parameter sequence; the execution equipment is used for generating corresponding waveforms based on the hardware parameter sequence, converting the waveforms into digital magnetic resonance data and sending the digital magnetic resonance data to the synchronous exchange equipment; the synchronous exchange equipment is also used for sending the digital magnetic resonance data to the image reconstruction module; the image reconstruction module is used for reconstructing an image based on the digital magnetic resonance data sent by the synchronous exchange equipment and sending the reconstructed image to the scanning module for presentation.
In some possible embodiments, the system further includes: the gate control module is connected with the synchronous switching equipment through a low-speed data interface; the gate control module is used for generating gate control data and sending the gate control data to the sequence module through the synchronous exchange equipment, so that the sequence module sends the hardware parameter sequence based on the gate control data.
In some possible embodiments, the synchronous switching device further includes: the system comprises a synchronous switching FPGA module, a first low-speed interface and a plurality of first high-speed interfaces; the synchronous switching FPGA module is respectively connected with the first low-speed interface, the plurality of first high-speed interfaces and the first reference clock module; the synchronous switching FPGA module comprises: the system comprises a first time sequence synchronization unit, a data exchange unit, a second low-speed interface, a plurality of second high-speed interfaces and a plurality of synchronous exchange data multiplexing units connected with the plurality of second high-speed interfaces; the first low-speed interface is connected with the second low-speed interface, and the plurality of first high-speed interfaces are respectively connected with the plurality of second high-speed interfaces.
In some possible embodiments, the execution device includes a second timing synchronization unit, and the second timing synchronization unit and the first timing synchronization unit jointly generate a reference signal.
In some possible embodiments, the first timing synchronization unit includes: an initial state, a link calibration state, a running state, and an error state; when the magnetic resonance spectrometer system is powered on, the first time sequence synchronization unit is in an initial state; when the magnetic resonance spectrometer system passes hardware inspection and sends inspection information to the first time sequence synchronization unit, the first time sequence synchronization unit is in a link calibration state; the first timing synchronization unit performs a delay test on the high-speed interface in the link calibration state, and if the result of the delay test is failure, the first timing synchronization unit enters the error state; if the result of the delay test is successful, the first time sequence synchronization unit enters a running state after the link delay value is transferred.
In a second aspect, an embodiment of the present invention provides a synchronization method for a distributed magnetic resonance spectrometer system, where the method includes: a first time sequence synchronization unit of the synchronous switching equipment generates a reference signal and sends the reference signal to the execution equipment through a first reference clock module; the above-mentioned execution apparatus includes: the system comprises a radio frequency transmitting module, a radio frequency receiving module and a gradient waveform generating module; and realizing time sequence synchronization and data exchange among the radio frequency transmitting module, the radio frequency receiving module and the gradient waveform generating module based on the reference signal.
In some possible embodiments, the method further comprises: the scanning module generates a scanning sequence based on input data and sends the scanning sequence to the sequence module; the sequence module compiles the scanning sequence into a hardware parameter sequence and sends the hardware parameter sequence to the synchronous exchange equipment; the synchronous exchange equipment sends the hardware parameter sequence to execution equipment through a high-speed data interface based on the data type of the hardware parameter sequence; the synchronous exchange equipment sends the digital magnetic resonance data to an image reconstruction module; the image reconstruction module reconstructs an image based on the digital magnetic resonance data sent by the synchronous exchange equipment, and sends the reconstructed image to the scanning module for presentation.
In a third aspect, an embodiment of the present invention provides an electronic device, including a memory and a processor, where the memory stores a computer program operable on the processor, and the processor implements the steps of the method according to any one of the first aspect when executing the computer program.
In a fourth aspect, embodiments of the present invention provide a computer-readable storage medium storing machine executable instructions that, when invoked and executed by a processor, cause the processor to perform the method of any of the first aspects.
The invention provides a distributed magnetic resonance spectrometer system and a synchronization method, wherein the system comprises synchronous exchange equipment, execution equipment and data generation equipment; the data generation equipment is connected with the synchronous switching equipment and sends the generated data to the synchronous switching equipment; the synchronous switching equipment is used for sending a reference signal to the execution equipment through the first reference clock module; the execution device includes: the system comprises a radio frequency transmitting module, a radio frequency receiving module and a gradient waveform generating module; the synchronous exchange equipment is also used for realizing time sequence synchronization and data exchange among the radio frequency transmitting module, the radio frequency receiving module and the gradient waveform generating module based on the reference signal. The system solves the technical problems of large phase deviation and low image quality caused by the layout of the conventional magnetic resonance spectrometer system, and achieves the technical effect of improving the phase synchronization stability.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.
FIG. 1 is a schematic diagram of a conventional magnetic resonance spectrometer system according to an embodiment of the present invention;
FIG. 2 is a schematic structural diagram of a distributed magnetic resonance spectrometer system according to an embodiment of the present invention;
FIG. 3 is a schematic diagram of an alternative distributed magnetic resonance spectrometer system according to an embodiment of the present invention;
fig. 4 is a schematic structural diagram of a synchronous switching device according to an embodiment of the present invention;
fig. 5 is a schematic structural diagram of a synchronous switching FPGA module according to an embodiment of the present invention;
fig. 6 is a schematic structural diagram of another synchronous switching device according to an embodiment of the present invention;
fig. 7 is a schematic structural diagram of an execution device according to an embodiment of the present invention;
FIG. 8 is a schematic diagram illustrating a state transition of a timing synchronization unit according to an embodiment of the present invention;
FIG. 9 is a schematic diagram illustrating a process of generating a reference point signal according to an embodiment of the present invention;
fig. 10 is a schematic structural diagram of an electronic device according to an embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention. Some embodiments of the invention are described in detail below with reference to the accompanying drawings. The embodiments described below and the features of the embodiments can be combined with each other without conflict.
It should be noted that: like reference numbers and letters refer to like items in the figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.
The magnetic resonance imaging system is composed of a number of sub-components, including in particular: magnetic resonance spectrometer, magnet, bed body, gradient power amplifier, radio frequency power amplifier, water cooling, receiving coil and scanning operation platform, etc. The spectrometer is a core component of a magnetic resonance imaging system, and a typical spectrometer system generally comprises the following structure shown in fig. 1: the system comprises a scanning computer, a sequence computer, an image reconstruction computer, a control computer, a sequence pulse generator, a radio frequency transmitting module, a radio frequency receiving module, a gradient waveform generating module and the like.
The magnetic resonance signal is a weak voltage signal, so the transmission loss of the magnetic resonance signal, especially the magnetic resonance signal with high field, on the coaxial cable is large. And the transmission of the magnetic resonance signal on the coaxial cable can introduce extra noise, so that the requirement that the receiving equipment of the spectrometer is placed between the magnets exists, the magnetic resonance signal is converted into a digital signal between the magnets, and the problem of the transmission of the magnetic resonance signal is solved. The existing spectrometer can realize the layout of the radio frequency receiving equipment between magnets through an optical fiber interface, such as: a communication card is designed based on the structure of the industrial personal computer, and the communication card is communicated with a host through a slot and communicated with receiving equipment through an optical fiber interface; for another example, a single board structure is adopted, and one or more optical interfaces are implemented on the board, through which the receiving board is arranged between the magnets.
However, the existing spectrometer still operates under the trigger of the synchronous sequence pulse, specifically, the sequence host issues the sequence data to the memories of the gradient waveform generation module and the radio frequency transmission module through the spectrometer network, and then converts the sequence data into a sequence waveform and outputs the waveform under the trigger of the sequence pulse.
The radio frequency receiving and the radio frequency transmitting of the spectrometer are phase coherent, and when the composition units of the spectrometer are intensively arranged among equipment, the phase coherence cannot be influenced because the wiring is short and the delay of the wiring is not large. However, if the radio frequency receiver of the spectrometer is placed between the magnets, the receiver and transmitter phases of the spectrometer will be very different. The existing spectrometer only simply arranges the radio frequency transceiver among magnets, and does not solve the phase problem caused by the enlarged path. With the development of the magnetic resonance technology, the number of receiving channels is increased, the number of receivers is increased, the phase is used as important information for imaging of the magnetic resonance system, and the deviation of the phase can bring about image artifacts, which seriously affects the quality of the image.
Based on this, the embodiment of the invention provides a distributed magnetic resonance spectrometer system and a synchronization method, so as to alleviate the technical problems of large phase deviation and low image quality caused by the layout of the magnetic resonance spectrometer system in the prior art.
To facilitate understanding of the present embodiment, first, a detailed description is given to a distributed magnetic resonance spectrometer system disclosed in the present embodiment, referring to a schematic structural diagram of a distributed magnetic resonance spectrometer system shown in fig. 2, where the system mainly includes: a synchronous switching device 200, an execution device 300, and a data generation device 100. The data generating device 100 is connected to the synchronous switching device 200, and transmits the generated data to the synchronous switching device 200;
the synchronous switching device 200 includes a first reference clock module 210; the synchronous switching device 200 is connected to the execution device 300; the synchronous switching device 200 is configured to send a reference signal to the execution device 300 through the first reference clock module.
The execution apparatus 300 includes: a radio frequency transmitting module 301, a radio frequency receiving module 302 and a gradient waveform generating module 303; the synchronous switching device 200 is further configured to implement timing synchronization and data switching among the rf transmitting module, the rf receiving module, and the gradient waveform generating module based on the reference signal.
Furthermore, in an embodiment, referring to fig. 3, the distributed magnetic resonance spectrometer system further comprises an image reconstruction module 130, and the data generation apparatus 100 comprises: a scan module 110 and a sequence module 120; the scan module 110 is connected to the sequence module 120 and the image reconstruction module 130, respectively.
The scan module 110 is configured to generate a scan sequence based on input data, and send the scan sequence to the sequence module 120; the sequence module 120 and the image reconstruction module 130 are respectively connected to the synchronous switching device 200 through communication card units; the sequence module 120 is configured to compile the scan sequence into a hardware parameter sequence and send the hardware parameter sequence to the synchronous switching device 200; the synchronous switching device 200 is configured to send the hardware parameter sequence to the execution device 300 through a high-speed data interface based on the data type of the hardware parameter sequence; the execution device 300 is configured to generate a corresponding waveform based on the hardware parameter sequence, convert the waveform into digital magnetic resonance data, and send the digital magnetic resonance data to the synchronous exchange device 200; the synchronous switching device 200 is further configured to send the digital magnetic resonance data to the image reconstruction module 130; the image reconstruction module 130 is configured to perform image reconstruction based on the digital magnetic resonance data sent by the synchronous switching device 200, and send a reconstructed image to the scanning module 110 for presentation.
As a specific example, the scanning module, the sequence module, and the image reconstruction module may each be separate computers, namely: a scanning computer, a sequence computer and an image reconstruction computer.
In addition, in the embodiment shown in fig. 3, the system further includes a gating module 140, where the gating module 140 is connected to the synchronous switch device 200 through a low-speed data interface; the gating module 140 is configured to generate gating data and send the gating data to the sequence module 120 through the synchronous switch device 200, so that the sequence module 120 sends the hardware parameter sequence based on the gating data.
As a specific example, the synchronous switching device may consist of the following structure shown in fig. 4: a first reference clock module 210, a synchronous switching FPGA module 220, a first low-speed interface 230, and a plurality of first high-speed interfaces 240; the synchronous switching FPGA module 220 is respectively connected to the first low-speed interface 230, the plurality of first high-speed interfaces 240, and the first reference clock module 210.
Further, the structure of the synchronous switching FPGA module 220 is shown in fig. 5: a first timing synchronization unit 221, a data exchange unit 222, a second low-speed interface 223, a plurality of second high-speed interfaces 224, and a plurality of synchronous exchange data multiplexing units 225 connected to the plurality of second high-speed interfaces 224; the first low-speed interface 230 is connected to the second low-speed interface 223, and the plurality of first high-speed interfaces 240 are connected to the plurality of second high-speed interfaces 224, respectively.
In addition, the first reference clock module may specifically include: a clock generator 211, an oven controlled crystal oscillator 212, a clock distributor 213 and a number of SMA interfaces 214; one end of the clock generator 211 is connected to the synchronous switching FPGA module 220; the other end of the clock generator 211 is connected to the output of the oven controlled crystal oscillator 212; the output of the oven controlled crystal oscillator 212 is connected to the clock distributor 213; the output of the clock distributor 213 is connected to several SMA interfaces 214 (see fig. 6).
Referring to the structural block diagram of a synchronous switching device shown in fig. 4, the synchronous switching device may further include a power supply network 250, a level conversion module 260 connected to the synchronous switching FPGA module, and a debugging serial port 261 connected to the level conversion module.
Furthermore, there is also a structure of the timing synchronization unit in the above-mentioned handshake FPGA module in the execution device, i.e. in one embodiment, the execution device may comprise a second timing synchronization unit that generates the reference signal in common with the first timing synchronization unit in the handshake device.
As a specific example, the structure of the execution apparatus is shown in fig. 7. A specific structure of the execution apparatus 300 includes: a third high-speed interface 310, an execution FPGA module 320, an analog circuit 330, a clock generation circuit 340 and an SMA interface connected with the clock generation circuit 340. The execution FPGA module 320 is connected to the third high-speed interface 310, the analog circuit 330, and the clock generation circuit 340, respectively.
Wherein, executing the FPGA module 320 includes: a fourth high speed interface 321, an execution data multiplexing unit 322, a FIFO memory 323, a second timing synchronization unit 324, and an execution logic unit 325. Both ends of the fourth high-speed interface 321 are connected to the third high-speed interface 310 and the execution data multiplexing unit 322, respectively; the execution data multiplexing unit 322 is connected to the FIFO memory 323 and the second timing synchronization unit 324, respectively; the second timing synchronization unit 324 is connected to the execution logic unit 325; the execution logic 325 is also coupled to the FIFO memory 323.
Generally, the timing synchronization unit is implemented by using a state machine, and the state machine can be further adjusted and optimized according to the specific implementation requirements.
In one embodiment, the first timing synchronization unit includes: an initial state, a link calibration state, a run state, and an error state. When the magnetic resonance spectrometer system is powered on, the first time sequence synchronization unit is in an initial state; when the magnetic resonance spectrometer system passes hardware inspection and sends inspection information to the first time sequence synchronization unit, the first time sequence synchronization unit is in a link calibration state; the first timing synchronization unit performs a delay test on the high-speed interface in the link calibration state, and if the result of the delay test is failure, the first timing synchronization unit enters the error state; if the result of the delay test is successful, the first time sequence synchronization unit enters a running state after the link delay value is transferred.
The invention provides a distributed magnetic resonance spectrometer system, which comprises synchronous exchange equipment, execution equipment and data generation equipment, wherein the synchronous exchange equipment is used for carrying out synchronous exchange on data; the data generation equipment is connected with the synchronous switching equipment and sends the generated data to the synchronous switching equipment; the synchronous switching equipment is used for sending a reference signal to the execution equipment through the first reference clock module; the execution device includes: the system comprises a radio frequency transmitting module, a radio frequency receiving module and a gradient waveform generating module; the synchronous exchange equipment is also used for realizing time sequence synchronization and data exchange among the radio frequency transmitting module, the radio frequency receiving module and the gradient waveform generating module based on the reference signal. The system solves the technical problems of large phase deviation and low image quality caused by the layout of the conventional magnetic resonance spectrometer system, and achieves the technical effect of improving the phase synchronization stability.
The embodiment of the application also provides a synchronization method of the distributed magnetic resonance spectrometer system, which comprises the following steps:
s10: a first time sequence synchronization unit of the synchronous switching equipment generates a reference signal and sends the reference signal to the execution equipment through a first reference clock module; the above-mentioned execution apparatus includes: the system comprises a radio frequency transmitting module, a radio frequency receiving module and a gradient waveform generating module;
s20: and realizing time sequence synchronization and data exchange among the radio frequency transmitting module, the radio frequency receiving module and the gradient waveform generating module based on the reference signal.
In one embodiment, the method further comprises: the scanning module generates a scanning sequence based on input data and sends the scanning sequence to the sequence module; the sequence module compiles the scanning sequence into a hardware parameter sequence and sends the hardware parameter sequence to the synchronous exchange equipment; the synchronous exchange equipment sends the hardware parameter sequence to execution equipment through a high-speed data interface based on the data type of the hardware parameter sequence; the synchronous exchange equipment sends the digital magnetic resonance data to an image reconstruction module; the image reconstruction module reconstructs an image based on the digital magnetic resonance data sent by the synchronous exchange equipment, and sends the reconstructed image to the scanning module for presentation.
As a specific example, the present application provides a distributed magnetic resonance spectrometer system, including: the system comprises a scanning computer, a sequence computer, a reconstruction computer, synchronous switching equipment, a radio frequency transmitting module, a gradient waveform generating module, a radio frequency receiving module and a gate control unit.
The synchronous exchange equipment is respectively connected with the sequence computer, the image reconstruction computer, the radio frequency transmitting module, the gradient waveform generating module and the radio frequency receiving module through high-speed interfaces and is connected with the gate control unit through a low-speed interface. In addition, the synchronous switching equipment provides a high-precision low-jitter reference clock for the radio frequency transmitting module, the radio frequency receiving module and the gradient waveform generating module, and the clock takes a coaxial cable as a connecting line.
The scanning computer may be connected to the sequence computer, the image reconstruction computer, via a network or other high speed interface. The image reconstruction computer may share the same computer as the scanning computer. One or more of the radio frequency transmit module, the gradient waveform generation module, the radio frequency receive module, and the gating unit may be integrated into a synchronous switching device.
The interface of the synchronous switching equipment mainly comprises a high-speed data interface, a low-speed data interface and a clock interface. The synchronous switching equipment sends reference signals to each component equipment or module in the system, and realizes data exchange among the component equipment or modules.
The FPGA firmware module of the synchronous switching equipment mainly comprises a data switching unit, a first time sequence synchronization unit, a synchronous switching data multiplexing unit and the like. The data exchange unit is used for exchanging the service data from different ports to the designated port according to different classes of the service data; the first timing synchronization unit is used for cooperating with a synchronization timing unit of other components (such as a second timing synchronization unit of an execution device) to jointly generate a timing reference signal; the synchronous exchange data multiplexing unit multiplexes the data from the time sequence synchronization unit and the data exchange unit to a channel, and the data given to the time sequence synchronization unit has the highest priority, so that the synchronous data is prevented from being influenced by the service data.
Furthermore, the synchronization method of the distributed magnetic resonance spectrometer system is mainly realized by a timing synchronization unit in each device forming the spectrometer system, namely, a first timing synchronization unit in the synchronous switching device and a second timing synchronization unit in each execution device, and the like. Specifically, the timing synchronization unit is implemented by using a state machine, and includes an initial state, a link calibration state, an operating state, and an error state, where the implementation of the four states and the switching process between the states are as follows:
after the distributed magnetic resonance spectrometer system is powered on, the state machine is in an initial state.
After hardware inspection is completed by hardware monitoring software running on a sequence host or an image reconstruction host, a complete message of spectrometer system equipment is sent to the synchronous switching equipment, and a timing synchronization unit enters a link calibration state after obtaining the message.
In the link calibration state, the timing synchronization unit will test the delay of the high-speed port connection, that is: the time sequence synchronization unit sends a data packet for a link delay test to the port and starts counting at the same time, the device at the opposite end may be a radio frequency transmitting module, a radio frequency receiving module or a gradient waveform generating module, the data packet is fed back immediately after the data is received, the synchronous switching device stops counting after receiving the feedback, and the number is divided by 2, so that the path delay of the link is obtained.
After the test is finished, if the test fails (such as overtime, too large or too small of a measured value), the timing synchronization unit enters an error state; if the test is successful, the hardware monitoring software reads the count value and writes the count value into a corresponding register of the opposite terminal equipment, and after the link delay value is transferred, the hardware monitoring software sends a message allowing operation to enable the time sequence synchronization unit to enter an operation state.
The spectrometer can scan in a running state, the sequence host can divide each scanning into a plurality of sequence segments, each sequence segment corresponds to a reference point, or the reference point can be sent once in one scanning, and the reference point can be called as a starting point of the scanning. The sequence host firstly sets a reference point and then sends the sequence segment, so that the executive equipment (the radio frequency receiving module, the radio frequency sending unit and the gradient waveform generating module) can generate a waveform and receive magnetic resonance data according to the reference point. In the run state, the monitoring software may notify the synchronization unit to retest if the link delay value is deemed incorrect. Fig. 8 shows a state transition diagram of the timing synchronization unit, and table 1 shows a state transition condition table of the timing synchronization unit.
TABLE 1 State transition Condition Table for timing synchronization Unit
And the synchronous switching equipment simultaneously sends a datum point generation message to the ports connected with the radio frequency transmitting module, the radio frequency receiving module and the gradient waveform generating module in the running state. After receiving the message, the corresponding device returns the feedback of receiving the message, and carries out different delays according to the length of the link.
The different delay is the total delay minus the path length, the total delay is an empirical value, and a value greater than the longest path can be selected to obtain the reference point signal of the device. The reference point signals of different devices are independent of the path length, and the deviation between the reference points of each device is at most the accuracy of one system clock. For example, assuming that the total delay time is 30 clock units, the cable length of the rf receiving module is 20 clock units, and the cable length of the rf transmitting module is 10 clock units, after different delay times, the rf receiving module and the rf transmitting module can generate a reference point signal with small deviation, and fig. 9 shows a generation process of the reference point signal. Meanwhile, a reference pulse is generated after a time delay.
The embodiment of the application provides a distributed magnetic resonance spectrometer system, and the distributed spectrometer architecture provided by the system solves the problem of phase coherence of a radio frequency transmitting module and a radio frequency receiving module, reduces the phase information deviation of a magnetic resonance signal, and improves the quality of an image. The embodiment of the application also provides a method for synchronizing the time sequence among the components of the spectrometer system, which is beneficial to realizing more reliable phase synchronization of the radio frequency link.
As shown in fig. 10, an electronic device 400 provided in an embodiment of the present application includes: a processor 40, a memory 41, a bus 42 and a communication interface 43, wherein the memory 41 stores machine-readable instructions executable by the processor 40, when an electronic device is operated, the processor 40 and the memory 41 perform device-to-device communication through the bus, and the processor 40 executes the machine-readable instructions to perform the steps of the method.
Specifically, the memory 41 and the processor 40 can be general-purpose memory and processor, which are not limited in particular, and the method can be performed when the processor 40 runs a computer program stored in the memory 41.
Corresponding to the method, the embodiment of the application also provides a computer readable storage medium, wherein the computer readable storage medium stores machine executable instructions, and when the computer executable instructions are called and executed by a processor, the computer executable instructions cause the processor to execute the steps of the method.
In the embodiments provided in the present application, it should be understood that the disclosed apparatus and method may be implemented in other ways. The above-described embodiments of the apparatus are merely illustrative, and for example, the division of the units is only one logical division, and there may be other divisions when actually implemented, and for example, a plurality of units or components may be combined or integrated into another system, or some features may be omitted, or not executed. In addition, the shown or discussed mutual coupling or direct coupling or communication connection may be an indirect coupling or communication connection of devices or units through some communication interfaces, and may be in an electrical, mechanical or other form.
The units described as separate parts may or may not be physically separate, and parts displayed as units may or may not be physical units, may be located in one place, or may be distributed on a plurality of network units. Some or all of the units can be selected according to actual needs to achieve the purpose of the solution of the embodiment.
In addition, functional units in the embodiments provided in the present application may be integrated into one processing unit, or each unit may exist alone physically, or two or more units are integrated into one unit.
The functions, if implemented in the form of software functional units and sold or used as a stand-alone product, may be stored in a computer readable storage medium. Based on such understanding, the technical solution of the present invention may be embodied in the form of a software product, which is stored in a storage medium and includes instructions for causing a computer device (which may be a personal computer, an electronic device, or a network device) to perform all or part of the steps of the method according to the embodiments of the present invention. And the aforementioned storage medium includes: a U-disk, a removable hard disk, a Read-Only Memory (ROM), a Random Access Memory (RAM), a magnetic disk or an optical disk, and other various media capable of storing program codes.
It should be noted that: like reference numbers and letters indicate like items in the figures, and thus once an item is defined in a figure, it need not be further defined or explained in subsequent figures, and moreover, the terms "first," "second," "third," etc. are used merely to distinguish one description from another and are not to be construed as indicating or implying relative importance.
Finally, it should be noted that: the above-mentioned embodiments are only specific embodiments of the present invention, which are used for illustrating the technical solutions of the present invention and not for limiting the same, and the protection scope of the present invention is not limited thereto, although the present invention is described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: any person skilled in the art can modify or easily conceive the technical solutions described in the foregoing embodiments or equivalent substitutes for some technical features within the technical scope of the present disclosure; such modifications, changes or substitutions do not depart from the spirit and scope of the embodiments of the present invention, and they should be construed as being included therein.
Claims (10)
1. A distributed magnetic resonance spectrometer system, comprising: synchronous exchange equipment, execution equipment and data generation equipment;
the data generation equipment is connected with the synchronous switching equipment and sends the generated data to the synchronous switching equipment;
the synchronous switching device comprises a first reference clock module; the synchronous switching equipment is connected with the execution equipment; the synchronous switching equipment is used for sending a reference signal to the execution equipment through the first reference clock module;
the execution device includes: the system comprises a radio frequency transmitting module, a radio frequency receiving module and a gradient waveform generating module; the synchronous exchange equipment is also used for realizing the time sequence synchronization and the data exchange among the radio frequency transmitting module, the radio frequency receiving module and the gradient waveform generating module based on the reference signal.
2. The distributed magnetic resonance spectrometer system according to claim 1, wherein the spectrometer system further comprises: an image reconstruction module; the data generation device includes: a scanning module and a sequence module;
the scanning module is respectively connected with the sequence module and the image reconstruction module; the scanning module is used for generating a scanning sequence based on input data and sending the scanning sequence to the sequence module;
the sequence module and the image reconstruction module are respectively connected with the synchronous switching equipment through a communication card unit; the sequence module is used for compiling the scanning sequence into a hardware parameter sequence and sending the hardware parameter sequence to the synchronous exchange equipment;
the synchronous exchange equipment is used for sending the hardware parameter sequence to the execution equipment through a high-speed data interface based on the data type of the hardware parameter sequence;
the execution equipment is used for generating corresponding waveforms based on the hardware parameter sequence, converting the waveforms into digital magnetic resonance data and sending the digital magnetic resonance data to the synchronous exchange equipment;
the synchronous exchange equipment is also used for sending the digital magnetic resonance data to the image reconstruction module;
the image reconstruction module is used for reconstructing an image based on the digital magnetic resonance data sent by the synchronous exchange equipment and sending the reconstructed image to the scanning module for presentation.
3. The distributed magnetic resonance spectrometer system according to claim 2, further comprising: the gate control module is connected with the synchronous switching equipment through a low-speed data interface;
the gating module is used for generating gating data and sending the gating data to the sequence module through the synchronous switching equipment, so that the sequence module sends the hardware parameter sequence based on the gating data.
4. The distributed magnetic resonance spectrometer system of claim 1, wherein the synchronous switching device further comprises: the system comprises a synchronous switching FPGA module, a first low-speed interface and a plurality of first high-speed interfaces;
the synchronous switching FPGA module is respectively connected with the first low-speed interface, the plurality of first high-speed interfaces and the first reference clock module;
the synchronous switching FPGA module comprises: the system comprises a first time sequence synchronization unit, a data exchange unit, a second low-speed interface, a plurality of second high-speed interfaces and a plurality of synchronous exchange data multiplexing units connected with the plurality of second high-speed interfaces;
the first low-speed interface is connected with the second low-speed interface, and the plurality of first high-speed interfaces are respectively connected with the plurality of second high-speed interfaces.
5. The distributed magnetic resonance spectrometer system according to claim 4, characterized in that the execution device comprises a second timing synchronization unit which generates a reference signal in combination with the first timing synchronization unit.
6. The distributed magnetic resonance spectrometer system according to claim 4, wherein the first timing synchronization unit comprises: an initial state, a link calibration state, a running state, and an error state;
when the magnetic resonance spectrometer system is powered on, the first time sequence synchronization unit is in an initial state;
when the magnetic resonance spectrometer system passes hardware inspection and sends inspection information to the first timing synchronization unit, the first timing synchronization unit is in a link calibration state;
the first time sequence synchronization unit carries out delay test on a high-speed interface in the link calibration state, and if the result of the delay test is failure, the first time sequence synchronization unit enters the error state;
and if the result of the delay test is successful, the first time sequence synchronization unit enters an operating state after the link delay value is transferred.
7. A method of synchronizing a distributed magnetic resonance spectrometer system, comprising:
a first time sequence synchronization unit of the synchronous switching equipment generates a reference signal and sends the reference signal to the execution equipment through a first reference clock module; the execution device includes: the system comprises a radio frequency transmitting module, a radio frequency receiving module and a gradient waveform generating module;
and realizing the time sequence synchronization and the data exchange among the radio frequency transmitting module, the radio frequency receiving module and the gradient waveform generating module based on the reference signal.
8. The method of synchronizing a distributed magnetic resonance spectrometer system according to claim 7, further comprising:
the scanning module generates a scanning sequence based on input data and sends the scanning sequence to the sequence module;
the sequence module compiles the scanning sequence into a hardware parameter sequence and sends the hardware parameter sequence to the synchronous exchange equipment;
the synchronous exchange equipment sends the hardware parameter sequence to execution equipment through a high-speed data interface based on the data type of the hardware parameter sequence;
the synchronous exchange equipment sends the digital magnetic resonance data to an image reconstruction module;
the image reconstruction module carries out image reconstruction based on the digital magnetic resonance data sent by the synchronous exchange equipment and sends the reconstructed image to the scanning module for presentation.
9. An electronic device comprising a memory and a processor, wherein the memory stores a computer program operable on the processor, and wherein the processor implements the steps of the method of any of claims 7 to 8 when executing the computer program.
10. A computer readable storage medium having stored thereon machine executable instructions which, when invoked and executed by a processor, cause the processor to execute the method of any of claims 7 to 8.
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566877B1 (en) * | 2000-12-26 | 2003-05-20 | Koninklijke Philips Electronics, N.V. | Band-limited gradient waveforms |
| CN203138687U (en) * | 2013-03-05 | 2013-08-21 | 上海联影医疗科技有限公司 | Distributed type medical treatment control system and magnetic resonance imaging equipment |
| US20150051479A1 (en) * | 2012-04-11 | 2015-02-19 | Dignity Health | System and Method for Magnetic Resonance Imaging Using Three-Dimensional, Distributed, Non-Cartesian Sampling Trajectories |
| CN105607021A (en) * | 2015-12-22 | 2016-05-25 | 沈阳东软医疗系统有限公司 | Magnetic resonance spectrometer |
| CN106950521A (en) * | 2017-03-01 | 2017-07-14 | 上海东软医疗科技有限公司 | Nuclear magnetic resonance spectrometer and its scan method, radio-frequency transmissions and method of reseptance |
| CN113281689A (en) * | 2021-05-21 | 2021-08-20 | 电子科技大学 | Magnetic resonance distributed spectrometer |
-
2021
- 2021-08-27 CN CN202110996997.0A patent/CN113671428A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566877B1 (en) * | 2000-12-26 | 2003-05-20 | Koninklijke Philips Electronics, N.V. | Band-limited gradient waveforms |
| US20150051479A1 (en) * | 2012-04-11 | 2015-02-19 | Dignity Health | System and Method for Magnetic Resonance Imaging Using Three-Dimensional, Distributed, Non-Cartesian Sampling Trajectories |
| CN203138687U (en) * | 2013-03-05 | 2013-08-21 | 上海联影医疗科技有限公司 | Distributed type medical treatment control system and magnetic resonance imaging equipment |
| CN105607021A (en) * | 2015-12-22 | 2016-05-25 | 沈阳东软医疗系统有限公司 | Magnetic resonance spectrometer |
| CN106950521A (en) * | 2017-03-01 | 2017-07-14 | 上海东软医疗科技有限公司 | Nuclear magnetic resonance spectrometer and its scan method, radio-frequency transmissions and method of reseptance |
| CN113281689A (en) * | 2021-05-21 | 2021-08-20 | 电子科技大学 | Magnetic resonance distributed spectrometer |
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