CN103969612A - Multifunctional acquisition module for NMRI system - Google Patents
Multifunctional acquisition module for NMRI system Download PDFInfo
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- CN103969612A CN103969612A CN201310032406.3A CN201310032406A CN103969612A CN 103969612 A CN103969612 A CN 103969612A CN 201310032406 A CN201310032406 A CN 201310032406A CN 103969612 A CN103969612 A CN 103969612A
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Abstract
The invention relates to a multifunctional acquisition module for an NMRI system. The multifunctional acquisition module can improve NMRI quality, monitor magnet temperature in real time and stabilize system working frequency. The multifunctional acquisition module integrates functions, such as respiration/ECG-gating, magnet temperature acquisition and automatic tuning, required by the NMRI system to a micro-processing system composed of an analog micro-controller and a CPLD, is integrated to the interior of a spectrometer of the NMRI system through a backplane bus and is in network communication with a computer through the spectrometer. Compared with an existing discrete device for achieving the functions, the multifunctional acquisition module greatly improves the integration level of the system, so that hardware resources are saved, maintenance and operation are facilitated, software and hardware are convenient to update, and meanwhile the multifunctional acquisition module can be conveniently in communication with the upper computer.
Description
Technical field
The present invention relates to a kind of multi-functional acquisition module for nuclear magnetic resonance imaging system, be particularly related to a kind of central multi-functional acquisition module of nuclear magnetic resonance imaging system spectrometer that is integrated into, this module is mainly by the functions such as needed nuclear magnetic resonance imaging system breathing/ecg-gating, magnet temperature collection and hands-off tuning are integrated into same microprocessing systems, the integrated level that has improved system in improving Magnetic resonance imaging quality, Real-Time Monitoring magnet temperature and systems stabilisation frequency of operation, has facilitated the upgrading of operation, maintenance and software and hardware.
Technical background
The main integrated breathing/ecg-gating of this multi-functional acquisition module for nuclear magnetic resonance imaging system relating to, magnet temperature gathers and automatic tuning circuit three parts, and they are having great significance aspect raising Magnetic resonance imaging quality, stability magnets temperature and system works frequency.
Nuclear magnetic resonance imaging system is mainly made up of magnet, spectrometer and computing machine three parts.Wherein spectrometer is carried out pulse train, controls transmitting and the reception of radiofrequency signal, and acquisition of image data, is the core in nuclear magnetic resonance imaging system.Spectrometer is made up of multiple operational modules, and the invention that will set forth is herein the module that will be integrated into a central function opposite independent of spectrometer.
In nuclear magnetic resonance imaging system, breathing, the heartbeat etc. of human body can make system in the time of imaging, produce motion artifacts at present, so that reduces resolution and the signal to noise ratio (S/N ratio) of image.Therefore for improving nuclear magnetic resonance image quality, need a kind of working time that can control imaging sequence in nuclear magnetic resonance imaging system, make it and the breathing of human body, the identical equipment of eliminating motion artifacts of the rhythm and pace of moving things of heartbeat.Breathing/ecg-gating is exactly so a kind of equipment, and it is inputted the human body respiration signal being obtained by sensor and heart rate signal in single-chip microcomputer and process through amplification, analog to digital conversion afterwards, controls the required gate-control signal of imaging sequence to obtain.It has important realistic meaning in the picture quality that improves Magnetic resonance imaging.
The magnet of nuclear magnetic resonance imaging system can change and change along with magnet temperature, can have influence on immediately main field, and then affect the image quality of nuclear magnetic resonance imaging system.Therefore very important to ensureing image quality to magnet temperature collection and Real-Time Monitoring.
It is flexible that nuclear magnetic resonance imaging system has a kind of receiving coil.Different people is due to build difference, can cause in use coil shape to change, thereby cause coil inductance to change, but being the resonance frequency (being the frequency of operation of nuclear magnetic resonance imaging system) of fixing, receiving coil works, therefore need to regulate the voltage at receiving coil varactor two ends to reach the object that changes coil capacitance, thereby ensure that coil working is in fixing resonance frequency.On the other hand, when receiving coil is operated in resonance frequency, its signal intensity receiving is the strongest, and in the time that skew occurs the frequency of operation to coil, its signal intensity receiving also can reduce.Therefore the function of hands-off tuning equipment is exactly while there is skew, just to produce a scanning voltage that is added in coil varactor two ends when spectrometer detects the frequency of operation of coil, at this time the voltage of varactor can change along with scanning voltage, when the signal intensity receiving when coil reaches maximum again, illustrate that coil got back to its resonance frequency, system is just by this magnitude of voltage locking, allow coil be stabilized in this frequency of operation, thereby reached the object of hands-off tuning.
At present in nuclear magnetic resonance imaging system, breathing/ecg-gating, magnet temperature collection and automatic tuning capabilities are all to adopt discrete equipment to realize, each separate devices is undertaken by serial ports with communicating by letter of computing machine, its maximum disadvantage is exactly: serial ports of computers resource is often not enough, and easily burns out; These discrete equipment use loaded down with trivial details and poor stability, and the upgrading of equipment software and hardware is also cumbersome.
For this situation, the present invention has designed a kind of multi-functional acquisition module for nuclear magnetic resonance imaging system, breathing/ecg-gating, magnet temperature collection and automatic tuning capabilities are integrated into same microprocessing systems by this module, and be integrated into spectrometer inside by core bus, then communicate by spectrometer and computing machine.Because the communication between spectrometer and computing machine only needs a netting twine, therefore this multi-functional acquisition module has improved level of integrated system greatly, has saved hardware resource, also greatly facilitates the upgrading of operation, maintenance and the software and hardware of system equipment simultaneously.
Summary of the invention
The object of the present invention is to provide a kind of multi-functional acquisition module for nuclear magnetic resonance imaging system, in improving Magnetic resonance imaging quality, Real-Time Monitoring magnet temperature and systems stabilisation frequency of operation, improve the integrated level of system, save hardware resource, be convenient to the upgrading of maintenance and operation and software and hardware, also facilitate between host computer and communicate by letter simultaneously.
For achieving the above object, the invention provides a kind of multi-functional acquisition module that breathing/ecg-gating, magnet temperature collection and automatic tuning capabilities is integrated into same microprocessing systems, it mainly comprises: signal conditioning circuit, a simulation microcontroller ADUC845, CPLD and four parts of automatic tuning circuit that model is EPM570F256C.
First, signal conditioning circuit be to the breathing from sensor, electrocardio and temperature signal amplify, the processing such as filtering, it mainly comprises three tunnels.The first via is breath signal modulate circuit, and it is by two-stage amplifying circuit and single-ended transfer difference the electric circuit constitute, and first order amplifying circuit is the gain control stages being made up of AD8221, and input differential signal is exported corresponding gain control signal.Second level amplifying circuit is made up of double operational OP2177, the incoming level of the rear amplifier of corresponding raising as required, the current potential of raising output signal.Being connected to after amplifying circuit is the single-ended transfer difference circuit being made up of AD8476, the differential input signal that it provides described simulation microcontroller to need; The second tunnel is the modulate circuit of electrocardiosignal, and it is by one-level amplifying circuit and single-ended transfer difference the electric circuit constitute, and wherein a lattice amplifier of OP2177 forms one-level amplifying circuit, the single-ended transfer difference circuit that AD8476 forms; Third Road is temperature signal regulation circuit, and its composition is identical with described electrocardiosignal modulate circuit.
Second, simulation microcontroller ADUC845, its analog input end receives and carries out AD conversion and processing from the differential signal of described signal conditioning circuit and to it, information exchange after treatment is crossed to CPLD and core bus is uploaded to spectrometer simultaneously, be uploaded to PC by spectrometer by netting twine again, to realize the mode of operation of man-machine interaction.
The 3rd, the CPLD that model is EPM570F256C, it is connected with automatic tuning circuit, described simulation microcontroller ADUC845 and core bus respectively, and reserves a part of IO mouth.It has the function of three aspects: the first, and it is stored the data from described ADUC845, and when needed data is uploaded to spectrometer and PC by core bus; The second, the digital quantity that produces a circulation linear change by programming is to automatic tuning circuit, and converts this digital quantity to linear corresponding analog voltage by automatic tuning circuit.The 3rd, reserved IO mouth, so that the expansion of other functions.
The 4th, automatic tuning circuit, converts linear corresponding analog voltage in order to the different digital amount that described CPLD is sent.It is mainly by two parts the electric circuit constitute.Part I circuit is the D/A converting circuit being made up of AD5344, and it is directly connected with CPLD, will convert the analog voltage of 0-5V to from the digital quantity of CPLD.Part II is made up of three-stage amplifier, and the first order is the gain control circuit being made up of OPA364, homophase output gain signal.The common emitter amplifying circuit that intergrade is made up of NPN transistor.The emitter follower that the third level is made up of PNP transistor.Through active amplification, automatic tuning circuit is finally exported the radio frequency reading voltage between 0-12V.
From the above mentioned, compared with traditional technology, the present invention has following technical advance:
A) adopt and there is the input of multichannel difference, be built-in with the simulation microcontroller and the CPLD composition microprocessing systems with 256 IO of 24 ADC, realize the functions such as collection, processing and the hands-off tuning of multiple signals, improved the integrated level of equipment, saved hardware resource.
B) multi-functional acquisition module is integrated in the middle of spectrometer by core bus, is convenient to the upgrading of maintenance and operation and software and hardware, also facilitate the communication between host computer simultaneously.
C) adopt AD8476 to realize differential signal input, improved the stability of input signal.
Brief description of the drawings
From referring to accompanying drawing detailed description of the preferred embodiment, by making, the structure and characteristics of multi-functional acquisition module is more clear.
Fig. 1 is the global design scheme block diagram of the multi-functional acquisition module of nuclear magnetic resonance imaging system.Wherein the part in dotted line frame is the logic diagram of circuit of multi-functional acquisition module, and the outer part of dotted line frame is the peripheral electronic device being connected with multi-functional acquisition module.
Fig. 2 is exhale/ecg-gating workflow block diagram.
Fig. 3 is ADUC845 simulation microcontroller internal processes workflow diagram in the time carrying out breathing/ecg-gating function.
Fig. 4 is the breath signal curve map that multi-functional acquisition module obtains.
Fig. 5 is the electrocardiosignal curve map that multi-functional acquisition module obtains.
Embodiment
One, referring to accompanying drawing, the embodiment that realizes breathing/ecg-gating function of the present invention is described.
1. the acquisition and processing of pair breath signal
Baroceptor produces different differential signals and signal is sent into the gain control circuit shown in accompanying drawing 1 according to human body respiration, the differential signal that AD8221 gain control circuit is sent here according to sensor is exported corresponding gain control signal, and the amplifying circuit of sending into rear one-level OP2117 formation carries out signal amplification, after amplifying circuit, signal becomes single-ended format by difference, therefore in order to realize difference input, finally transfer single-ended signal to differential signal by AD8476 again.
After modulate circuit, after breath signal, arrive the simulation microcontroller ADUC845 that is built-in with 24 A/D converters, then ADUC845 is uploaded to spectrometer by signal after treatment through CPLD and core bus, then is uploaded to computing machine as shown in Figure 2 by spectrometer by netting twine.Tester obtains breath signal curve map according to testing software on computers, as shown in Figure 4.Wherein, test has three kinds of curves on outside, and green line is the measured's of acquisition breath signal curve, and red line is threshold value line (can artificially set as required), and yellow line is the gate-control signal of controlling imaging sequence.As tester---when operator sees the not fogging clear of imaging system acquisition or has motion artifacts, threshold value can be rule of thumb manually set, change the position of red line on testing software interface, set suitable threshold value, now, the information of artificially setting threshold value is returned to ADUC845 by computing machine, ADUC845 microprocessing systems is exported corresponding gate-control signal according to the threshold value of setting, be that a series of pulses are given spectrometer to control its imaging sequence working time, thereby obtain image clearly.Wherein the formation of pulse is crossed into as shown in Figure 3, in the time starting to test, system is carried out initial setting by default value, set initial threshold value, and start to gather breath signal, ADUC845 compares gathering breath signal and the threshold value come, if breath signal is higher than threshold value, system output high level, otherwise output low level, now the low and high level of output is to control imaging sequence gate-control signal---the pulse train of working time, pulse train control system imaging sequence working time, if imaging clearly does not have artifact, allow system continue normal work, if imaging is unintelligible or have a motion artifacts, can artificially reset on computers threshold value, produce new gate sequence, until there is not motion artifacts in clear picture.
2. the acquisition and processing of pair electrocardiosignal
When same collection electrocardiosignal, voltage sensitive sensor transfers the jitter of human pulse to electric signal, and sent into the electrocardiosignal amplifying circuit directly being formed by OP2177 shown in accompanying drawing 1, the electrocardiosignal after amplification is the same with breath signal to be transferred to differential signal and is inputted ADUC845 simulation microcontroller and change and process by AD8476.After processing, also pulse train is given to spectrometer and control imaging sequence imaging obtaining electrocardiosignal as shown in Figure 5, being both on computers.In imaging process, the setting process of electrocardiosignal threshold value is identical as shown in Figure 3 with the setting of breath signal thresholding, and tester is by setting threshold value according to the experience of self, until obtain image clearly.
Two, referring to accompanying drawing, the embodiment that realizes temperature acquisition function of the present invention is described.
The gatherer process of temperature is as follows: as shown in Figure 1, signal is from the temperature sensor entering signal modulate circuit of magnet, after OP2177 amplifying circuit, transferred to differential signal input simulation microcontroller ADUC845 by AD8476, send into CPLD through ADUC845 conversion and signal after treatment, in the time that needs read, PC is read away the data in CPLD by the core bus of spectrometer.
Three, referring to accompanying drawing, the embodiment that realizes automatic tuning capabilities is described.
As shown in Figure 1, in the time that spectrometer detects the frequency of operation off-resonance frequency of receiving coil, just send instruction by core bus to the CPLD of multi-functional acquisition module and carry out with the program starting in CPLD.This program sends data to DA converter from 0 to 255 circulation of automatic tuning circuit, the data-switching receiving is become change modeling magnitude of voltage between 0-5V by DA, this analog voltage is raised to 0-12V through three-stage amplifier again and is added to the two ends of receiving coil varactor, and the scanning voltage therefore constantly changing between this 0-12 will constantly change the electric capacity of varactor.Because in the time that receiving coil is operated in resonance frequency, its signal intensity receiving is the strongest, and in the time that skew occurs the frequency of operation to coil, its signal intensity receiving also can reduce.So when the signal intensity receiving when coil reaches maximum again, illustrate that coil got back to its resonance frequency, now spectrometer just sends instruction to the CPLD of multi-functional collection plate and allows CPLD by the magnitude of voltage locking of automatic tuning circuit.Now just reach tuning object.
Can see by above 4 embodiment, realize multiplexed signal sampling, processing and automatic tuning capabilities taking ADUC845 and CPLD as the microprocessing systems of core, improve the integrated level of equipment, save hardware resource.And multi-functional acquisition module is integrated in the middle of spectrometer by core bus, be convenient to the upgrading of maintenance and operation and software and hardware, also facilitate the communication between host computer simultaneously.
Claims (5)
1. for a multi-functional acquisition module for nuclear magnetic resonance imaging system, comprising: signal conditioning circuit, to the signal from sensor amplify, the processing such as filtering; A simulation microcontroller, carries out AD conversion and processing to the signal through described signal conditioning circuit processing, and signal after treatment is delivered to CPLD; A CPLD, is connected with automatic tuning circuit, described simulation microcontroller and core bus respectively, and reserves a part of IO mouth and be convenient to the expansion of other functions; Automatic tuning circuit, the different digital amount that described CPLD is sent converts linear corresponding analog voltage to.
2. signal conditioning circuit according to claim 1, it comprises three tunnels.The first via is breath signal modulate circuit, and it is by two-stage amplifying circuit and single-ended transfer difference the electric circuit constitute, and first order amplifying circuit is the gain control stages being made up of AD8221, and input differential signal is exported corresponding gain control signal.Second level amplifying circuit is made up of double operational OP2177, the incoming level of the rear amplifier of corresponding raising as required, the current potential of raising output signal.Be connected to amplifying circuit liver be the single-ended transfer difference circuit being formed by AD8476, the differential input signal that it provides described simulation microcontroller to need; The second tunnel is the modulate circuit of heart rate signal, and it is by one-level amplifying circuit and single-ended transfer difference the electric circuit constitute, and wherein a lattice amplifier of OP2177 forms one-level amplifying circuit, and AD8476 forms single-ended transfer difference circuit; Third Road is the temperature signal reason circuit that withers, and its composition is identical with described heart rate signal modulate circuit.
3. simulation microcontroller according to claim 1, its model is ADUC845, its analog input end receives and carries out AD conversion and processing from the differential signal of described signal conditioning circuit and to it, information exchange after treatment is crossed to CPLD and core bus is uploaded to spectrometer simultaneously, be uploaded to PC by spectrometer by netting twine again, to realize the mode of operation of man-machine interaction.
4. CPLD according to claim 1, its model is EPM570F256C, it has the function of three aspects: the first, it is stored the data from described ADUC845, and when needed data is uploaded to spectrometer and PC by core bus; The second, the digital quantity that produces a circulation linear change by programming is to automatic tuning circuit, and converts this digital quantity to linear corresponding analog voltage by automatic tuning circuit.The 3rd, reserved IO mouth, so that the expansion of other functions.
5. automatic tuning circuit according to claim 1, it is mainly by two parts the electric circuit constitute.Part I circuit is the D/A converting circuit being made up of AD5344, and it is directly connected with CPLD, will convert the analog voltage of 0-5V to from the digital quantity of CPLD.Part II is made up of three-stage amplifier, and the first order is the gain control circuit being made up of OPA364, homophase output gain signal.The common emitter amplifying circuit that intergrade is made up of NPN transistor.The emitter follower that the third level is made up of PNP transistor.Through active amplification, automatic tuning circuit is finally exported the radio frequency reading voltage between 0-12V.
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| CN105607021A (en) * | 2015-12-22 | 2016-05-25 | 沈阳东软医疗系统有限公司 | Magnetic resonance spectrometer |
| CN105894767A (en) * | 2015-12-16 | 2016-08-24 | 沈阳东软医疗系统有限公司 | Magnetic resonance attachment signal sending method, transmission method, device and system |
| CN106997033A (en) * | 2016-01-22 | 2017-08-01 | 北京大学 | A kind of multi-channel magnetic resonance RF transmission method and device |
| CN107806909A (en) * | 2017-09-13 | 2018-03-16 | 南京农业大学 | A kind of impulse type cereal flow transducer signal acquisition and processing apparatus |
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Application publication date: 20140806 |