CN105607021B - A kind of nuclear magnetic resonance spectrometer - Google Patents
A kind of nuclear magnetic resonance spectrometer Download PDFInfo
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- CN105607021B CN105607021B CN201510973771.3A CN201510973771A CN105607021B CN 105607021 B CN105607021 B CN 105607021B CN 201510973771 A CN201510973771 A CN 201510973771A CN 105607021 B CN105607021 B CN 105607021B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
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Abstract
The application provides a kind of nuclear magnetic resonance spectrometer, comprising: scanning and reconstruction computer control scanning element, comprising: scanning resonance engine, digital actuation engine, scanning sequence control module and digital signal processing module；Scanning resonance engine is connect with scanning with computer is rebuild, for generating scanning sequence control subevent, digital actuation engine subevent and Digital Signal Processing subevent, it is respectively sent to digital actuation engine, digital signal processing module and scanning sequence control module；Digital actuation engine, connect with gradient amplifier and radio frequency amplifier, for generating gradient waveform signal and radio frequency waveform signal；Digital signal processing module is connect with digital RF receiving unit and scanning with computer is rebuild respectively, is used for image reconstruction for receiving magnetic resonance imaging signal and transmitting a signal to scanning and rebuild computer.Nuclear magnetic resonance spectrometer provided by the present application is to improve the picture quality of magnetic resonance.
Description
Technical field
This application involves Medical Devices technology, in particular to a kind of nuclear magnetic resonance spectrometer.
Background technique
Magnetic resonance (magnetic resonance, MR) is the stationary magnetic field generated using the magnet in magnetic resonance system,
By the control to radio frequency system and gradient system, magnetic resonance signal is excited by radio frequency system and is received, and utilize gradient
Magnetic field carries out excitation to sample and selects layer and space encoding, to obtain a kind of tomograph imaging method for having spatial positional information.
Nuclear magnetic resonance spectrometer is a kind of equipment used in MR imaging method, is penetrated for generate that radio frequency system uses
The gradient waveform that frequency waveform, gradient system use, and can receive magnetic resonance signal.In the related technology, spectrometer is usually to put
The centralized device in control room is set, each functional module such as waveform generation module, signal receiving module is usually all concentrated and set
It is placed in same equipment, and is connect spectrometer with components such as radio frequency amplifier, gradient amplifier, radio-frequency coils by cable
Carry out signal transmission.The shortcomings that spectrometer of this structure is that the picture quality of magnetic resonance imaging is bad.
Summary of the invention
In view of this, the application provides a kind of nuclear magnetic resonance spectrometer, to improve the picture quality of magnetic resonance.
Specifically, the application is achieved by the following technical solution:
In a first aspect, providing a kind of nuclear magnetic resonance spectrometer, comprising:
Scanning and reconstruction computer, for generating magnetic resonance imaging information；
Control scanning element, comprising: scanning resonance engine, digital actuation engine, scanning sequence control module and number letter
Number processing module；
The scanning resonance engine is connect, for receiving and parsing the magnetic resonance with the scanning with computer is rebuild
Scanning information obtains scanning sequence control subevent, digital actuation engine subevent and Digital Signal Processing subevent；It will be described
Digital actuation engine subevent is sent to digital actuation engine, and Digital Signal Processing subevent is sent to Digital Signal Processing mould
Scanning sequence control subevent is sent to scanning sequence control module by block；
The digital actuation engine, connect with gradient amplifier and radio frequency amplifier, for being drawn according to the digital actuation
It holds up subevent and generates gradient waveform signal and radio frequency waveform signal, the gradient waveform signal is sent to gradient amplifier, it will
The radio frequency waveform signal is transmitted to radio frequency amplifier；
The digital signal processing module connect with digital RF receiving unit and scanning with computer is rebuild respectively, uses
In: subevent is handled according to the digital signal receives the magnetic resonance imaging signal that the digital RF receiving unit obtains, and
The magnetic resonance imaging signal is transmitted to the scanning and is used for image reconstruction with computer is rebuild；
The scanning sequence control module, connect with digital actuation engine and digital signal processing module respectively, is used for root
Event, which is sent, to digital actuation engine and digital signal processing module respectively according to scanning sequence control subevent triggers clock,
And magnet electronic unit is connected, radio-frequency coil control information, peripheral hardware and gating information are transmitted between the magnet electronic unit.
Nuclear magnetic resonance spectrometer provided by the present application, by using distributed spectrometer structure, so that each function in spectrometer
Component can be arranged apart, by these functional components by link be connected with each other, in this way can by magnetic resonance system not
Same functional component is arranged in different positions, for example digital RF receiving unit can be arranged close to radio-frequency coil, even
Digital RF receiving unit can be arranged in radio-frequency coil, the electrical noise in signal long-distance transmission can be reduced in this way,
It improves signal quality and implements also more flexible to improve the picture quality of magnetic resonance.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of nuclear magnetic resonance spectrometer shown in one exemplary embodiment of the application；
Fig. 2 is the motion flow of the scanning resonance engine shown in one exemplary embodiment of the application；
Fig. 3 is the motion flow of the scanning sequence control module shown in one exemplary embodiment of the application；
Fig. 4 is the motion flow of the digital actuation engine shown in one exemplary embodiment of the application；
Fig. 5 is the motion flow of the multi-modal signal transmitting unit shown in one exemplary embodiment of the application；
Fig. 6 is the motion flow of the magnet electronic unit shown in one exemplary embodiment of the application；
Fig. 7 is the motion flow of the digital RF receiving unit shown in one exemplary embodiment of the application；
Fig. 8 is the structure of the expanding digital rf receiver unit shown in one exemplary embodiment of the application；
Fig. 9 is the motion flow of the digital signal processing module shown in one exemplary embodiment of the application.
Specific embodiment
Example embodiments are described in detail here, and the example is illustrated in the accompanying drawings.Following description is related to
When attached drawing, unless otherwise indicated, the same numbers in different drawings indicate the same or similar elements.Following exemplary embodiment
Described in embodiment do not represent all embodiments consistent with the application.On the contrary, they be only with it is such as appended
The example of the consistent device and method of some aspects be described in detail in claims, the application.
This application provides a kind of nuclear magnetic resonance spectrometer, which designs using distributed structure, may refer to Fig. 1's
Spectrometer structural schematic diagram, comprising: scanning and reconstruction computer 11, (unit is digital scan control to scan control unit 12
Unit, that is, the signal generated are digital signals), (unit is optionally present multi-modal signal transmitting unit 13, subsequent example
Be described in detail), magnet electronic unit 14 and digital rf receiver unit 15.Wherein, scan control unit 12 may include: scanning resonance
Engine 121, digital actuation engine 122, scanning sequence control module 123 and digital signal processing module 124.
Scanning resonance engine 121 is connect with scanning with computer 11 is rebuild, and be can receive scanning and is rebuild computer 11 and sends out
The magnetic resonance imaging information sent, for example, scan event list and sweep parameter etc..Scanning resonance engine 121 can also parse magnetic
Resonance scan information is respectively obtained for controlling at digital actuation engine 122, scanning sequence control module 123 and digital signal
Manage the digital actuation engine subevent, scanning sequence control subevent and Digital Signal Processing of the work of these three modules of module 124
Subevent, and digital actuation engine subevent is sent to digital actuation engine, Digital Signal Processing subevent is sent to
Scanning sequence control subevent is sent to scanning sequence control module by digital signal processing module.And scan resonance engine
121, between digital actuation engine 122, scanning sequence control module 123 and digital signal processing module 124, high speed can be passed through
Differential signal realizes high speed data transfer.
Digital actuation engine 122 can be connect with gradient amplifier 16 and radio frequency amplifier 17, for being resonated according to scanning
The digital actuation engine subevent that engine 121 is sent generates gradient waveform signal and radio frequency waveform signal, by gradient waveform signal
It is sent to gradient amplifier 16, radio frequency waveform signal is transmitted to radio frequency amplifier 17.I.e. digital actuation engine 122 can be responsible for
Gradient and radiofrequency signal are generated, the magnetostatic square deviation of the proton in magnetic resonance imaging body can be made magnetostatic by the two signals
The axial direction of field.After stopping applying radiofrequency signal, proton will be restored to normal spin states, and generate deamplification i.e. magnetic resonance
Imaging signal, which can be received by digital RF receiving unit 15, and be transmitted to digital signal processing module 124.
Digital signal processing module 124 is connect with digital RF receiving unit 15, and is connected scanning and rebuild computer,
Receive digital RF receiving unit 15 magnetic resonance imaging signal after, which can be transmitted to scanning with
It rebuilds computer 11 and is used for image reconstruction.
Scanning sequence control module 123 is connect with digital actuation engine 122 and digital signal processing module 124 respectively, is used
Event touching is sent to digital actuation engine 122 and digital signal processing module 124 respectively in controlling subevent according to scanning sequence
Clock is sent out, the time of radio frequency waveform and gradient waveform is generated for controlling the two modules.Scanning sequence control module 123 also connects
Magnet electronic unit 14 is connect, radio-frequency coil control information and peripheral hardware and gating information are transmitted between magnet electronic unit 14,
For example, can control the reiving/transmitting state of radio-frequency coil, coil temperature, magnet operating status etc. can also be obtained.
Spectrometer exemplified by Fig. 1 in this example is a distributed spectrometer structure, i.e., each function part in spectrometer
Part can be it is separated, for example, multi-modal signal transmitting unit 13, digital RF receiving unit 15, magnet electronic unit 14, with
Scan control unit 12 is three physically separate parts, these functional components are connected with each other by link.This
The benefit of kind of structure is that functional component different in magnetic resonance system can be arranged in different positions, such as can be by number
Word rf receiver unit 15 is arranged close to radio-frequency coil, it might even be possible to which digital RF receiving unit 15 is arranged in radio-frequency coil
In, the electrical noise in signal long-distance transmission can be reduced in this way, improved signal quality, implemented also more flexible.Magnet
Electronic unit 14 can be arranged between magnet, collect the device status information between magnet with nearest distance, and with most in short-term
It is interior to send control information to radio-frequency coil and peripheral hardware and gate.
It in another example, can be by broadband between the distributed each funtion part of spectrometer referring to the example of Fig. 1
Optical fiber link connection, for example, scanning resonance engine 121 is connect by broadband optical fiber link with scanning with computer 11 is rebuild, number
Word incentives engine 122 can be connect, at digital signal with gradient amplifier 16 and radio frequency amplifier 17 by broadband optical fiber link
Module 124 is managed, is connect by broadband optical fiber link with digital RF receiving unit 15, and scanned by broadband optical fiber link connection
With reconstruction computer 11, magnetic resonance imaging signal can be received by digital RF receiving unit 15, and pass through broadband optical fiber link
It is transmitted to digital signal processing module 124, then image is used for computer 11 is rebuild by broadband optical fiber link transmission to scanning
It rebuilds.Scanning sequence control module 123 also passes through broadband optical fiber link connection magnet electronic unit 14.This connection type is high
The anti-interference of signal can be improved in the connection of speed digital formula.For example, digital RF receiving unit 15 is penetrated receiving multichannel
After the magnetic resonance imaging signal that frequency coil 18 generates, which can be transmitted to scan control unit with digital signal form,
Quality after signal transmission can be improved.
In addition, signal transmission quality not only can be improved in the spectrometer structure of this example, the speed of signal processing can also be improved
Degree, referring to the structure that Fig. 1 illustrates, in scan control unit 12, scanning resonance engine 121 and digital signal processing module 124,
It can be respectively by different broadband optical fiber link connection scanning and reconstruction computer 11, for example, scanning resonance engine 121 passes through
The connection of broadband optical fiber link 19 scanning is connected with computer 11, digital signal processing module 124 is rebuild by broadband optical fiber link 20
It connects scanning and rebuilds computer 11, allow for scan control bus in this way and receive data/address bus independence, broadband light can be passed through
Fine link 19 transmits the coherent signal of scan control, and transmits received magnetic resonance imaging signal by broadband optical fiber link 20,
It realizes the parallel processing of two aspects, accelerates conversion speed.Also, this structure is also conducive to realize real time scan, scanning
Control unit can be scanned with real-time reception and rebuild the magnetic resonance information of the transmission of computer 11, and parse the information for magnetic resonance
Signal generate and received control.
The work and realization principle of each functional module of the nuclear magnetic resonance spectrometer are illustrated respectively as follows:
Scanning and reconstruction computer
Exemplary scanning and reconstruction computer 11, can be used to implement creation, editor and the compiling of scanning sequence in Fig. 1,
The example for being scanned sequence obtains personalized scanning sequence, this, which changes, refers to that doctor can be according to current scanned individual
The characteristics of and scanning need, set on the basis of general scanning sequence and some executing magnetic resonance for the scanned individual
Sweep parameter when scanning.Scanning sequence exploitation and scanning sequence example environment can use graphicalization mode, program description side
Formula or text input mode, are scanned the example of sequence, ultimately generate the scanning thing for particular subject scanning application
Part list and sweep parameter, the scan event list and sweep parameter are properly termed as magnetic resonance imaging information.
Scanning can be by scan event list and sweep parameter by reaching under broadband optical fiber link with reconstruction computer 11
The scanning resonance engine 121 of scan control unit 12, the broadband optical fiber link connection are configured at scanning and rebuild in computer 11
The optical fiber link interface of portion's slot.Scanning may also receive from the digital signal of scan control unit 12 with computer 11 is rebuild
The magnetic resonance imaging signal that processing module 124 is sent, and scanning sequence example parameter is combined to carry out image reconstruction.Scanning and reconstruction
The control logic of computer 11 can be not limited to above-mentioned part.
Scanning resonance engine
The execution process of scanning resonance engine 121 may refer to shown in Fig. 2, and scanning resonance engine 121 can pass through broadband
Optical fiber link receives scanning and rebuilds the scan event list and sweep parameter of the transmission of computer 11.Scanning resonance engine 121 can
Parsed to received scan event list and sweep parameter according to scan event label information, scanning is parsed
Timing control subevent, digital actuation engine subevent and Digital Signal Processing subevent.And it can be according to sweep parameter pair
Subevent is defined and constrains, and generates scan event and is cyclically updated parameter, is distributed to scanning sequence control module, digital actuation
Engine modules and digital signal processing module.As shown in Fig. 2, digital actuation engine subevent is sent to digital actuation engine 122,
Scanning sequence control subevent is sent to scanning sequence control module 123, and Digital Signal Processing subevent is sent to digital signal
Processing module 124.
Above-mentioned each subevent that scanning resonance engine 121 parses, such as: digital actuation engine subevent or number
Signal processing subevent may include the action message of timing control information and each operational module, wherein timing control information packet
Containing each subevent initial time and duration is scanned, action message includes modules required movement, such as digital actuation
The required movement of engine 122-radio frequency generates and transmitting, gradient are generated and sent, and specifying for digital signal processing module 124 is dynamic
The acquisition of work-resonance signal and processing.
The sweep parameter that scanning resonance engine 121 parses, may include restricted and definition timing control and each work
The parameter of the movement of module, such as radio-frequency pulse amplitude, frequency and initial phase, radio-frequency pulse shape type and data data point
Number, gradient waveform slope and rise time, signal acquisition points and acquisition interval and signal acquisition time started are at the end of
Between etc..
Scanning sequence control module 123 receives the timing information of entire sequence, and digital actuation engine 122 is received to be produced with waveform
Raw relevant timing information and action message, digital signal processing module 124 receive timing information relevant to data acquisition and
Action message.The processing of these three modules is subsequent to be described in detail respectively.
During the scanning process, scanning resonance engine 121 can scan the update sent with reconstruction computer 11 with real-time reception
Magnetic resonance imaging information, i.e. scan event update and its sweep parameter updates, and real time parsing distributes to scanning sequence and controls mould
In block 123, digital actuation engine 122 and digital signal processing module 124, the setting of corresponding scanning subevent and parameter is changed；
Under conditions of all modules complete current subevent, it is transferred to the response processing of the subevent sequence of update, realizes that scanning is real-time
Property control.
Scanning sequence control module
The motion flow of scanning sequence control module 123 may refer to shown in Fig. 3, can receive and parses scanning resonance and draws
The scanning sequence control subevent for holding up 121 transmissions, obtains the time shaft scanning motion information of scanning sequence, and can receive magnetic
The peripheral hardware collected of body electronic unit 14 and gating information, the peripheral hardware information include the portions such as magnet, gradient coil and radio-frequency coil
The status signal of part, gating information for example may include the physiology gate-control signal such as ecg-gating and respiration gate control.
In conjunction with the information that the peripheral state signal and physiology gate-control signal and parsing scanning sequence control subevent obtain, sweep
Radio-frequency pulse generation axis, slice selective gradient axis, phase code axis and frequency coding axis can be calculated by retouching time-sequence control module 123
The synchronous triggering clock in subevent, i.e., event triggers clock, and is distributed to digital actuation engine 122 and Digital Signal Processing mould in real time
Block 124, as the reference clock source of spectrometer system, for driving the operation of spectrometer each unit module, so that each scanning is sub
Event executes whole scanning according to scheduled scanning sequence.Each scanning motion synchronous triggering signal shown in Fig. 3 (for example,
Radio-frequency pulse generates axis scanning motion synchronous triggering signal) i.e. above-mentioned event triggers clock.
Digital actuation engine
The motion flow of digital actuation engine 122 can as shown in connection with fig. 4, which, which can receive, comes
The digital actuation engine subevent of self-scanning resonance engine 121 and its corresponding sweep parameter, and parse the digital actuation engine
Subevent and sweep parameter, the radio-frequency pulse for obtaining scanning sequence generate axis, slice selective gradient axis, phase code axis and frequency coding
The scanning motion information of axis, the parallel radio-frequency pulse number letter for completing that there is selected bandwidth, centre frequency, amplitude and initial phase
Number generation, have selected gradient time-to-climb, preemphasis time constant, climb altitude and the slice selective gradient axis of duration,
The generation of phase code axis and the digital gradient waveform signal of frequency coding axis direction and each TR (repetition
Time, repetition time) scanning during phase code axis gradient waveform amplitude update numerical value.
After this, digital actuation engine 122 follows the radio-frequency pulse inputted from scanning sequence control module 123 and generates axis
The synchronous touching of scanning motion synchronous triggering signal, slice selective gradient axis scanning motion synchronous triggering signal, phase code axis scanning motion
The timing signaled with frequency coding axis scanning motion synchronous triggering signal, it is parallel defeated according to scanning sequence list of thing sequence
Digital RF pulse signal, digital slice selective gradient pulse signal, digit phase encoding gradient pulse signal and numerical frequency are compiled out
Code gradient pulse signal, during each TR, the scanning sequence control logic provided according to scanning sequence control module 123 is complete
It is encoded at the excitation and generation of electromagnetic induction phenomenon, and to the reading of resonance signal.Digital actuation engine 122 receives gradient simultaneously
Vortex correction result is calculated, and accordingly generates gradient eddy high-order compensation digital signal.
Multi-modal signal transmitting unit
What the multi-modal signal transmitting unit 13 was optionally present in spectrometer, the gradient imported for analog signal is put
Big device and radio frequency amplifier, the output end of the input terminal and multi-modal signal transmitting unit 13 of gradient amplifier and radio frequency amplifier
It is connected, to obtain analog radio-frequency signal and simulation gradient signal, and multi-modal signal transmitting unit 13 passes through broadband optical fiber link
Broadband high-speed data transmission is realized with the digital actuation engine 122 of scan control unit 12, is swashed with transmitting digital gradient and radio frequency
Waveform signal is encouraged, i.e., the gradient waveform signal and radio frequency waveform that digital actuation engine 122 generates are received by broadband optical fiber link
Signal, and gradient amplifier and radio frequency amplification are sent to after the gradient waveform signal and radio frequency waveform signal are carried out digital-to-analogue conversion
Device.The gradient amplifier imported for digital signal and radio frequency amplifier can save multi-modal signal transmitting unit 13, gradient
The input terminal of amplifier and radio frequency amplifier can be directly real with the output end of digital actuation engine 122 by broadband optical fiber link
Existing Broadband high-speed data transmission.
Shown in Figure 5, multi-modal signal transmitting unit 13 can be by Digital Signals module 51, more RF pulse-to-pulse punch dies
Quasi- signal generator module 52, double gradient pulse analog signal generation modules 53 and high-order shimming signal generator module 54 are constituted.It is more
Mode signals transmission unit 13 is received as produced by the digital actuation engine 122 of scan control unit 12 by High-speed Optical Fiber Link
Digital stimulus signal, sort out each road radio-frequency pulse, gradient pulse and shimming gradient using Digital Signals module 51
Waveform signal provides input signal for one or more radio frequency amplifiers and one or more gradient amplifiers.
Every road RF pulse signal stream is input to corresponding high-speed DAC digital analog converter, filters by radio frequency low-noise band logical
RF pulse signal is amplified to 0dBmW amplitude, exported to corresponding radio frequency amplifier by wave amplifying element.Every road is penetrated
Frequency pulse signal may include the radio-frequency pulse output waveform signals in multiple channels of different center frequency, to support multichannel to penetrate
The output of frequency pulse signal.
There is the gradient pulse signal stream of digital preemphasis to be separately input into corresponding high-speed DAC digital analog converter on three tunnels,
Corresponding gradient pulse output signal is produced by respective signal adjustment transform part, output to gradient source, which switches, switchs
Three road gradient pulse signals are transferred to specified gradient through gradient source switching switch and amplified by (i.e. gradient signal source switching switch)
Device.Switch switch by the gradient source, can support the input of more gradient amplifiers.Feelings are configured for single gradient amplifier
Shape, three-dimensional gradient pulse output 1 can be set effectively for gradient source switching switch or three-dimensional gradient pulse exports 2 effectively.
In addition, every road gradient eddy high-order compensation digital signal is input to corresponding high-speed DAC digital analog converter, by letter
Number conditioning link and power drive link export into corresponding gradient eddy high-order compensation coil.
Magnet electronic unit
The motion flow of magnet electronic unit 14 in spectrometer may refer to Fig. 6, which may include:
CAN communication interface module 61, PIN drive module 62, physiology gate interface module 63, peripheral state interface module 64.
CAN communication interface module 61 can be realized and scanning sequence control in scan control unit 12 by High-speed Optical Fiber Link
The CAN bus of molding block 123 communicates, which not only includes radio-frequency coil control information, for example radio-frequency coil receives and dispatches shape
The biography down of state control command and receiving coil passage switching control command, further includes but is not limited to gradient coil, radio-frequency coil, magnetic
The upload of the peripheral states such as body and physiology gate waveform signal.
PIN drive module 62 obtains radio-frequency coil reiving/transmitting state control command from CAN communication interface module 61, drives radio frequency
The switching of the transmission state and detuning state of transmitting coil drives each RF receiving coil realization in RF receiving coil group to connect
The switching of receipts state and detuning state.
Physiology gate interface module 63 complete ecg-gating signal, breath gate-control signal and periphery gate-control signal acquisition with
Processing, and realize the transmitting that physiology gate data are carried out to CAN communication interface module 61.
Peripheral state interface module 64 is used to collect the peripheral states such as gradient coil, radio-frequency coil, magnet, including but unlimited
In the state of temperature of gradient coil, the access state of radio-frequency coil and operating status, the operating status of magnet, and to digital RF
Receiving unit input radio frequency receiving channel gates control command.
Digital RF receiving unit
Shown in Figure 7, digital RF receiving unit 15 in spectrometer can be according to transmitting through magnet electronic unit 14
The timing information of scanning sequence control module 123 is opened and closed radio frequency reception channel, receives and handle magnetic resonance imaging signal.Number
Rf receiver unit 15 may include Clock management module 71, data strobe and interface communication module 72 and at least one multichannel
Receiver Module 73, wherein each multi-channel radio frequency receiving module 73 is connect at least one Multi-channel radio-frequency coil, is used for
Receive the magnetic resonance imaging signal that the Multi-channel radio-frequency coil is sent.
According to clinical scanning needs, multiple digital RF receiving units 15 can be configured, constitute digital RF receiving unit
Group is realized and matches interconnection with multi-channel coil group.The extension of radio frequency reception channel may be implemented in digital RF receiving unit 15,
The quantity of extension in scan control unit 12 digital signal processing module 124 extend quantity can be it is corresponding, with
Guarantee upload of the high-speed broadband with radio frequency reception data.For example, the clinical application for that can support body scan mode, can adopt
It is corresponding with Multi-channel radio-frequency coil group used by body scan mode with the mode of expanding digital rf receiver unit, such as
Fig. 8 example.
Digital RF receiving unit 15 can be placed near Multi-channel radio-frequency coil group, for receiving Multi-channel radio-frequency coil
Group magnetic resonance signal, can also be assemblied in each radio-frequency coil of Multi-channel radio-frequency coil group for each digital RF receiving unit 15
In, realize the reception of digitized magnetic resonance.
Clock management module 71 can will carry out quality from the System Clock Reference signal of scan control unit 12
To change, Clock Managing Unit has the mutually cascade structure of twin-lock, the dither cycle of clock signal is restricted within the scope of 100 femtoseconds,
To improve the signal-to-noise ratio of digital-to-analogue conversion.
The acquisition of these peripheral hardware information of the status signal of the components such as magnet, gradient coil and radio-frequency coil and ecg-gating
With the acquisition of the physiology gate-control signal such as respiration gate control, directly it can realize that data pass by optical fiber link and magnet electronic unit 14
It is defeated, and via the scan control unit 12 of total digitalization, it is uploaded to scanning and rebuilds computer 11.Multi-channel radio-frequency coil group is logical
Radio-frequency cable connection magnet electronic unit 14 is crossed, coil state changeover control signal is obtained.
On the one hand data strobe and interface communication module 72 realize the CAN communication interface module with magnet electronic unit 14
61 data communication is responsible for Multi-channel radio-frequency coil type and abnormal state information passing to magnet electronic unit 14, be received
It is swept in the related multi-channel radio frequency signal condition link of CAN communication interface module 61 from magnet electronic unit 14 based on difference
Retouch the control signal that mode carries out channel gating and signal condition；On the other hand the digital signal with scan control unit 12 is realized
The data communication of processing module 124 is responsible for matching to Multi-channel radio-frequency coil output impedance and frequency tuning control amount, reception number
The digital RF that word Signal Pretreatment is exported receives signal.
Each multi-channel radio frequency receiving module 73 may include penetrating for what is handled the magnetic resonance imaging signal
Frequency signal condition mould group, analog-to-digital conversion mould group and Signal Pretreatment mould group.As shown in fig. 7, in radiofrequency signal conditioning mould group, that is, Fig. 7
Multi-channel radio frequency signal condition, analog-to-digital conversion mould group, that is, A/D analog-to-digital conversion group, Signal Pretreatment mould group, that is, multi-channel digital letter
Number preprocessing part.Wherein, multi-channel radio frequency signal condition mould group is made of multiple radio frequency reception channels, can receive one or
The magnetic resonance signal of multiple radio-frequency coil outputs, controllably increases for completing the magnetic resonance signal low noise of each receiving channel parallel
Benefit adjustment and the radiofrequency signals processing operation such as bandpass filtering treatment and necessary IF Modulation；A/D analog-to-digital conversion group by with penetrate
The A/D analog to digital conversion means of frequency receiving channel number corresponding number is constituted, for complete parallel the direct of multi-channel radio frequency signal or
Intermediate frequency digital-to-analogue conversion operation；Multichannel digital signal pre-processes mould group by the digital signal with radio frequency reception channel number corresponding number
It pre-processes link to constitute, for the preliminary extraction operation of if sampling data after each digital-to-analogue conversion of Parallel Implementation, or directly adopt
The image frequency acquisition of sample and preliminary extraction operation, to reduce the transmission bandwidth of each radio frequency reception channel digital signal.
Digital signal processing module
The motion flow of digital signal processing module 124 in the scan control unit 12 of spectrometer may refer to Fig. 9, the number
Word signal processing module 124 may include: channel data sorting, Digital Signal Processing group, data buffering group and data packaging with
The parts such as data transmission.
Wherein, channel data sorting is responsible for sorting out connecing for each channel from the data that digital RF receiving unit transmits
Data are received, and are distributed in each digital signal processing channel of Digital Signal Processing group.Digital Signal Processing group includes multiple
Digital signal processor for channel, for magnetic resonance signals such as down-converted and the FFT transform of completing each channel data parallel
Digital Signal Processing operation.
Data buffering group includes that the data of quantity identical as the digital signal processor for channel in Digital Signal Processing group are slow
Device is rushed, for completing the data buffer storage of channel digital signal processing parallel, to complete the transmission of the packaging and data of data.
Data packaging is used to complete to from this digital signal processing module and other digital signals with data transmission link
Processing module data packaging and data processing, with realize digital signal processed data to scanning with rebuild computer upload and
Realize the extension of digital signal processing module.
The nuclear magnetic resonance spectrometer of the application, by using distributed spectrometer system, and each function of system as described above
Digital transmission all can be carried out using wideband optical fiber transmission and interconnection between module, improve the anti-interference of transmission signal,
The signal-to-noise ratio of radio frequency reception channel is improved, and then can be improved picture quality；Also, also take some raising scan controls
The measure of real-time, the signaling rate of Lai Tigao scan control, for example, scan control bus and reception data/address bus is only
It is vertical, support real-time sequence scanning, each Receiver Module in digital RF receiving unit carries out independent signal condition
With Digital Signal Processing operation, it can be achieved that the radio frequency reception of bigger bandwidth, improves the reality of gradient waveform and its preemphasis processing
Shi Xing also improves the processing speed of signal；By being amplified using multi-modal signal transmitting unit to gradient amplifier and radio frequency
Device output signal enables the spectrometer to support more radio frequency source transmittings and the output of more gradient sources；In addition, digital RF receiving unit
It can also be extended, support the whole body images scanning mode of more receiving coils while access；This distributed spectrometer structure
Flexible design exploitation is also more adapted to, meets low High-Field whole body clinical scanning demand, the time resolution of scan control can also be improved
Rate improves the purity of frequency spectrum of radio frequency output.By test, using the nuclear magnetic resonance spectrometer of the application, the real-time of scan control and
Picture quality is improved.
The foregoing is merely the preferred embodiments of the application, not to limit the application, all essences in the application
Within mind and principle, any modification, equivalent substitution, improvement and etc. done be should be included within the scope of the application protection.
Claims (9)
1. a kind of nuclear magnetic resonance spectrometer, which is characterized in that the nuclear magnetic resonance spectrometer is distributed spectrometer structure, the spectrometer packet
It includes:
Scanning and reconstruction computer, for generating magnetic resonance imaging information；
Scan control unit, comprising: at scanning resonance engine, digital actuation engine, scanning sequence control module and digital signal
Manage module；
The scanning resonance engine is connect, for receiving and parsing the magnetic resonance imaging with the scanning with computer is rebuild
Information obtains scanning sequence control subevent, digital actuation engine subevent and Digital Signal Processing subevent；By the number
Incentives engine subevent is sent to digital actuation engine, and Digital Signal Processing subevent is sent to digital signal processing module,
Scanning sequence control subevent is sent to scanning sequence control module；
The digital actuation engine, connect with gradient amplifier and radio frequency amplifier, for according to digital actuation engine
Event generates gradient waveform signal and radio frequency waveform signal, and the gradient waveform signal is sent to gradient amplifier, will be described
Radio frequency waveform signal is transmitted to radio frequency amplifier；
The digital signal processing module connect with digital RF receiving unit and scanning with computer is rebuild respectively, is used for: root
The magnetic resonance imaging signal that the digital RF receiving unit obtains is received according to the Digital Signal Processing subevent, and will be described
Magnetic resonance imaging signal is transmitted to the scanning and rebuilds computer for image reconstruction；
The scanning sequence control module, connect with digital actuation engine and digital signal processing module respectively, for according to institute
It states scanning sequence control subevent and sends event triggering clock to digital actuation engine and digital signal processing module respectively, and even
Magnet electronic unit is connect, radio-frequency coil control information, peripheral hardware and gating information are transmitted between the magnet electronic unit；
The digital RF receiving unit, comprising: multiple multi-channel radio frequency receiving modules；
Each multi-channel radio frequency receiving module, connect, for receiving the multi-pass at least one Multi-channel radio-frequency coil
The magnetic resonance imaging signal that road radio-frequency coil is sent；And the multi-channel radio frequency receiving module include for the magnetic resonance at
Radiofrequency signal conditioning mould group, analog-to-digital conversion mould group and the Signal Pretreatment mould group handled as signal；
The digital RF receiving unit, the magnet electronic unit and the physically separate setting of scan control unit.
2. nuclear magnetic resonance spectrometer according to claim 1, which is characterized in that
The scanning resonance engine is connect by wideband link with the scanning with computer is rebuild；The digital actuation engine is logical
Wideband link is crossed to connect with gradient amplifier and radio frequency amplifier；The digital signal processing module passes through wideband link and number
Rf receiver unit connection, and pass through wideband link connection scanning and reconstruction computer；The scanning sequence control module passes through
Wideband link connects magnet electronic unit.
3. nuclear magnetic resonance spectrometer according to claim 2, which is characterized in that
The scanning resonance engine and digital signal processing module are scanned and are rebuild with described by different wideband links respectively
Computer connection.
4. nuclear magnetic resonance spectrometer according to claim 1, which is characterized in that
The scanning resonance engine, is also used to: scanning described in real-time reception is sent more with computer is rebuild during the scanning process
New magnetic resonance imaging information, and be sent to the digital actuation engine after update magnetic resonance imaging information described in real time parsing, sweep
Retouch time-sequence control module and digital signal processing module.
5. nuclear magnetic resonance spectrometer according to claim 1, which is characterized in that the nuclear magnetic resonance spectrometer includes: multiple numbers
Word rf receiver unit.
6. nuclear magnetic resonance spectrometer according to claim 1, which is characterized in that the nuclear magnetic resonance spectrometer includes: multiple number letters
Number processing module.
7. nuclear magnetic resonance spectrometer according to claim 1, which is characterized in that the digital RF receiving unit is assemblied in institute
It states in Multi-channel radio-frequency coil.
8. nuclear magnetic resonance spectrometer according to claim 1, which is characterized in that the gradient amplifier imported for analog signal
And radio frequency amplifier, the nuclear magnetic resonance spectrometer further include: multi-modal signal transmitting unit；The multi-modal signal transmitting unit,
For receiving the gradient waveform signal and radio frequency waveform signal that the digital actuation engine generates by wideband link, and will be described
Gradient waveform signal and radio frequency waveform signal are sent to gradient amplifier and radio frequency amplifier after carrying out digital-to-analogue conversion.
9. nuclear magnetic resonance spectrometer according to claim 1, which is characterized in that scanning resonance engine, digital actuation engine,
Between scanning sequence control module and digital signal processing module, high speed data transfer is realized by high-speed differential signal.
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| CN110192858A (en) * | 2018-02-27 | 2019-09-03 | 鸿海精密工业股份有限公司 | NMR imaging instrument and dementia previewing system |
| CN108414957A (en) * | 2018-03-06 | 2018-08-17 | 莒县人民医院 | A kind of real-time magnetic resonance image-forming data acquisition analysis method and system |
| CN110531291B (en) * | 2019-08-26 | 2021-09-28 | 中国科学院合肥物质科学研究院 | Topological structure of high-intensity magnetic field condensed nuclear magnetic resonance spectrometer system |
| CN113331815A (en) * | 2020-03-02 | 2021-09-03 | 哈尔滨医科大学 | Multi-core radio frequency coil transceiving and ultrasonic array unit synchronous control device and method |
| CN111521963B (en) * | 2020-05-06 | 2021-02-19 | 电子科技大学 | Method for automatically adapting and outputting gradient waveform rate and magnetic resonance system |
| CN112379317B (en) * | 2020-06-15 | 2021-05-18 | 武汉中科牛津波谱技术有限公司 | Nuclear magnetic resonance pulse sequence controller |
| CN113219390A (en) * | 2021-05-21 | 2021-08-06 | 电子科技大学 | Method for dynamically updating scanning parameters through magnetic resonance |
| CN113671433A (en) * | 2021-08-12 | 2021-11-19 | 上海康达卡勒幅医疗科技有限公司 | Magnetic resonance spectrometer with integrated and distributed combined structure |
| CN113655423B (en) * | 2021-08-27 | 2024-05-28 | 康达洲际医疗器械有限公司 | High-instantaneity magnetic resonance spectrometer system and management method |
| CN113671428A (en) * | 2021-08-27 | 2021-11-19 | 康达洲际医疗器械有限公司 | Distributed magnetic resonance spectrometer system and synchronization method |
| CN117331009A (en) * | 2023-12-01 | 2024-01-02 | 中国科学技术大学先进技术研究院 | Spectrometer receiving method and device |
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| KR101234715B1 (en) * | 2011-09-30 | 2013-02-19 | 주식회사 아이솔테크놀로지 | Signal processing device using distributed digital spectrometer |
| CN102551722B (en) * | 2012-01-12 | 2013-09-11 | 辽宁开普医疗系统有限公司 | Full digital spectrometer-based magnetic resonance imaging system |
| KR20130091444A (en) * | 2012-02-08 | 2013-08-19 | 삼성전자주식회사 | Magnetic resonance imaging device |
| CN103105599B (en) * | 2012-05-29 | 2014-12-31 | 辽宁开普医疗系统有限公司 | Magnetic resonance receiving coil with high-speed serial interface |
| CN103969612A (en) * | 2013-01-28 | 2014-08-06 | 北京大学 | Multifunctional acquisition module for NMRI system |
| CN103549955B (en) * | 2013-11-14 | 2016-05-04 | 嘉恒医疗科技有限公司 | A kind of method and system of magnetic resonance imaging multiple signals transmission |
| CN103901375B (en) * | 2014-03-06 | 2016-06-08 | 北京大学 | A kind of magnetic resonance imaging spectrometer based on high speed interconnection serial bus |
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