CN113293088A

CN113293088A - Automatic point vibration machine for centrifugal bottle

Info

Publication number: CN113293088A
Application number: CN202110606632.2A
Authority: CN
Inventors: 周亚楠; 张航; 石小娟; 王倩; 王嘉显
Original assignee: Help Stem Cell Innovations Co ltd
Current assignee: Help Stem Cell Innovations Co ltd
Priority date: 2021-06-01
Filing date: 2021-06-01
Publication date: 2021-08-24

Abstract

The invention belongs to the technical field of biology, and relates to an automatic point vibration machine for a centrifugal bottle, which comprises a point vibration unit, wherein the point vibration unit comprises: a drive mechanism having an output shaft that outputs a rotational torque; the point vibration eccentric disc is arranged at the output end of the output shaft in an eccentric mode and rotates by taking the output shaft as an axis; defining that the eccentric mode is that the axis of the point vibration eccentric disc and the axis of the output shaft are arranged in parallel and have a set distance; a centrifugal bottle clamp which is arranged on the point vibration eccentric disc in a mode of having elastic freedom degree in the axial direction relative to the point vibration eccentric disc; by definition, the axial direction is a direction parallel to the axis of the output shaft. And the technical scheme of this application can realize among the automatic control system a plurality of centrifuge bottles from moving point shake.

Description

Automatic point vibration machine for centrifugal bottle

Technical Field

The invention belongs to the technical field of biology, and relates to an automatic vibration-dropping machine for a centrifugal bottle.

Background

When the adherent cells are cultured, the adherent cells are attached to the surface of a culture dish and can continuously proliferate until the cells are spread on the surface of the whole cell factory, and at the moment, the cells in the cell factory can be digested and collected.

After the cell collection was completed, the cells were centrifuged and the supernatant was removed. Many cells are still in a state of conglomeration or connection, and the cell conglomeration needs to be separated by adopting a shaking mode. Pipette blows and manual turbine oscillator oscillations are now common.

The blowing and shaking processes are manual operation, and the conditions of low efficiency and unstable operation exist. Meanwhile, the problems of high labor intensity and overlong waiting time of other centrifuge bottles exist in the operation of a plurality of centrifuge bottles.

Therefore, it is necessary to design a new device to realize the automatic shaking operation of the centrifuge bottle. The new device does not need manual operation, reduces the pollution risk, improves the efficiency and reduces the cost.

Disclosure of Invention

The invention aims to provide an automatic vibration-igniting machine for a centrifugal bottle, which can realize automatic vibration-igniting of the centrifugal bottle in an automatic control system.

In order to achieve the above purpose, the invention provides the following technical scheme: an automatic vibration-igniting machine for a centrifuge bottle, comprising a vibration-igniting unit, the vibration-igniting unit comprising:

a drive mechanism having an output shaft that outputs a rotational torque;

the point vibration eccentric disc is arranged at the output end of the output shaft in an eccentric mode and rotates by taking the output shaft as an axis; defining that the eccentric mode is that the axis of the point vibration eccentric disc and the axis of the output shaft are arranged in parallel and have a set distance;

a centrifugal bottle clamp which is arranged on the point vibration eccentric disc in a mode of having elastic freedom degree in the axial direction relative to the point vibration eccentric disc; by definition, the axial direction is a direction parallel to the axis of the output shaft.

As the improved technical scheme of the application, the point vibration eccentric disc is arranged at the output end of the output shaft through a crankshaft; the output shaft drives the crankshaft to rotate through a coupler.

As the improved technical scheme of the application, the point vibration eccentric disc is installed on the crankshaft through a bearing, and the point vibration eccentric disc is elastically connected to the inner wall of the shell of the automatic point vibration machine of the centrifugal bottle.

As an improved technical scheme of the application, the number of the point vibration units is multiple, and the point vibration units are uniformly distributed; the point vibration eccentric discs in the point vibration unit are mounted on the crankshaft through bearings, and the adjacent two point vibration eccentric discs are elastically connected.

As an improved technical scheme of the application, the number of the point vibration units is multiple, point vibration eccentric discs in any adjacent two point vibration units in each point vibration unit have different initial rotation angles, and the initial angles of the point vibration eccentric discs in each point vibration unit are designed in a symmetrical mode.

As the improved technical scheme of the application, the centrifugal bottle clamp is provided with a base, a centrifugal bottle supporting seat and an elastic clamping piece; the centrifuge bottle supporting seat is integrated on the base, and the upper surface part of the centrifuge bottle supporting seat is sunken to form a bottom positioning part matched with the bottom of the centrifuge bottle; the elastic clamping piece is provided with a plurality of upright posts and at least one auxiliary ring; one end of each upright column surrounds the centrifuge bottle supporting seat and is fixed on the base to form a centrifuge bottle side surface clamping structure, and the other end of each upright column is bent reversely to form a reinforcing ring; the auxiliary ring surrounds all the upright posts and is connected with the lower parts of all the upright posts.

As an improved technical scheme of the application, the centrifugal bottle clamp further comprises a plurality of guide pins with protruding parts, a plurality of through holes are annularly distributed on the point vibration eccentric disc, one end of each guide pin is fixed at the bottom of the centrifugal bottle clamp, and the other end of each guide pin is limited by the protruding part of the guide pin after penetrating through the through hole; meanwhile, a spring is arranged on the section of the guide pin, which is positioned between the bottom of the centrifugal bottle clamp and the point vibration eccentric disc.

As the improved technical scheme of the application, the driving mechanism is provided with a zero returning device.

As the improved technical scheme of the application, the centrifugal bottle vibration device further comprises an outer protection device, wherein the outer protection device is provided with a centrifugal bottle placing table and a centrifugal bottle vibration point area which are adjacently arranged; the point vibration unit is arranged in the point vibration area of the centrifugal bottle through a point vibration substrate.

As this application modified technical scheme, the centrifugal flask point shakes the district and is in the cover has been laid to the top that the unit was shaken to the centrifugal flask point, set automatic mechanism of uncapping on the cover to at the cover in when the unit was shaken to the centrifugal flask point was gone up, the cover with the centrifugal flask top that the unit bore was shaken to the centrifugal flask point contacts.

Has the advantages that:

according to the technical scheme, the invention provides the automatic point vibration machine for the centrifugal bottle, which realizes vibration through the circular motion of the point vibration eccentric disc driven by the servo motor and the elastic freedom degree in the axial direction. The servo motor is adopted for controlling, so that the matching operation of the mechanical arm and the point vibration unit can be met, and the automatic point vibration operation of the centrifugal bottle can be realized.

This application centrifugal bottle passes through centrifugal bottle anchor clamps location fixed and shakes on the eccentric disc at the point, shakes the vibration that the eccentric disc realized the high frequency through the point and realizes that centrifugal bottle point shakes. The multiple centrifugal oscillation devices can be simultaneously carried out and independently controlled, and the point oscillation efficiency is greatly improved.

The point vibration eccentric disc adopts servo control (servo motor drive) and position control (determining rotation starting position and zero setting), so that the phase position after point vibration is unique, and the repeated positioning precision required by matching with a robot is ensured.

The point vibration intensity of the point vibration unit is controlled by the servo motor in real time, and the real-time adjustment of the point vibration speed can be realized.

The multiple point shakes the unit in this application, and the control is originated angle symmetric design, realizes shaking angle phase difference control, guarantees the dynamic balance of whole vibration, effectively reduces the board vibrations.

This application cover disposes automatic device of uncapping, during the use, uncaps automatically, puts into the centrifugal flask after, automatic lid of closing, shakes the in-process simultaneously and pushes down centrifugal bottle lid in the point, and the gesture of centrifugal flask avoids beating when keeping shaking.

This application adopts the centrifugal flask to place the structure of platform and centrifugal flask point vibration district unification, reduces the equipment vibrations that the centrifugal flask vibrates and brings by a wide margin.

It should be understood that all combinations of the foregoing concepts and additional concepts described in greater detail below can be considered as part of the inventive subject matter of this disclosure unless such concepts are mutually inconsistent.

The foregoing and other aspects, embodiments and features of the present teachings can be more fully understood from the following description taken in conjunction with the accompanying drawings. Additional aspects of the present invention, such as features and/or advantages of exemplary embodiments, will be apparent from the description which follows, or may be learned by practice of specific embodiments in accordance with the teachings of the present invention.

Drawings

The drawings are not intended to be drawn to scale. In the drawings, each identical or nearly identical component that is illustrated in various figures may be represented by a like numeral. For purposes of clarity, not every component may be labeled in every drawing. Embodiments of various aspects of the present invention will now be described, by way of example, with reference to the accompanying drawings, in which:

FIG. 1 is a schematic view of the automatic bottle-dropping machine according to the present application;

FIG. 2 is a schematic diagram of a point vibration unit according to the present application;

FIG. 3 is a schematic structural diagram of a crankshaft of the present application;

FIG. 4 is a schematic diagram illustrating a layout structure of a plurality of seismic units according to the present application;

FIG. 5 is a schematic view of the design of the starting angle of the point-vibration eccentric disc according to the present application;

in the figure: 1. a centrifuge bottle placing rack; 2. a joint; 3. a machine cover; 4. a drive mechanism; 5. point vibration of the eccentric disc; 6. a centrifuge bottle clamp; 61. a base; 62. a centrifugal bottle supporting seat; 63. an elastic clamping member; 64. a reinforcing ring; 65. an auxiliary ring; 7. point vibration of the substrate; 8. a crank; 9. a main shaft.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the drawings of the embodiments of the present invention. It is to be understood that the embodiments described are only a few embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the described embodiments of the invention without any inventive step, are within the scope of protection of the invention. Unless defined otherwise, technical or scientific terms used herein shall have the ordinary meaning as understood by one of ordinary skill in the art to which this invention belongs.

As shown in fig. 1-2, the present application provides an automatic point vibration machine for a centrifuge bottle, which fixes the centrifuge bottle on a point vibration eccentric disc 5 through a centrifuge bottle clamp 6, and the point vibration eccentric disc 5 performs circular motion driven by a driving mechanism 4 and vibration controlled by a servo motor due to elastic freedom of the point vibration eccentric disc 5 in the axial direction during the motion process. It can realize vibrating the phase controllable through selecting for use actuating mechanism 4, and each centrifugal flask independently can realize a plurality of centrifugal flasks and shake by the centre gripping is fixed, in addition, can adopt the robotic arm to carry out automated control point through detection device's design and shake.

In order to better explain the technical solution of the present application, the following detailed description is made with reference to specific examples.

As shown in figure 1, the automatic vibration-igniting machine for the centrifugal bottle is provided with an external protection device in practical application. Different from the prior art, the outer protection device of the application is provided with a centrifugal bottle placing table and a centrifugal bottle vibration point area which are adjacently arranged; the point vibration unit is arranged in the point vibration area of the centrifugal bottle through a point vibration substrate 7. Place the platform through the centrifuge bottle and set up with the unification of centrifuge bottle point vibrations district, realize utilizing the centrifuge bottle weight district that the centrifuge bottle placed platform department to slow down the whole vibrations of the in-process external point vibration machine of shaking of point. Simultaneously, the unification sets up, and the process is shaken to the point in the convenient automation line for the robotic arm can get fast and take the centrifugal flask to carry out the point and shake. And the centrifugal bottle placing table can be set to have a plurality of centrifugal bottle placing sites, each centrifugal bottle placing site is provided with a centrifugal bottle placing rack 1, and the centrifugal bottle placing rack 1 can bear a plurality of centrifugal bottles. The centrifuge bottle placing rack 1 in the embodiment can adopt the centrifuge bottle placing rack 1 in the prior art, the improvement is that a connector 2 for a robot arm to grab is arranged on the side surface of the centrifuge bottle placing rack 1, and the model of the connector 2 is determined according to an operator of the robot arm.

Simultaneously, in some embodiments, in order to avoid some to shake in-process centrifuge bottle by shaking out, also for the convenience realize automated control, centrifuge bottle point shakes the district and is in centrifuge bottle point shakes the top of unit and has laid cover 3, set automatic uncapping mechanism on the cover 3 to cover 3 in when the cover 3 covers on the centrifuge bottle point shakes on the unit, cover 3 with the centrifuge bottle top that the unit bore is shaken to the centrifuge bottle point contacts. The machine cover 3 comprises an outer cover body and an outer cover body driving device; the outer cover body is arranged above the point vibration area of the centrifugal bottle through an outer cover body driving device.

The outer cover driving device comprises a rotating motor, a rotating shaft connected to an output shaft of the rotating motor and a magnetic induction angle sensor used for detecting a rotating angle of the rotating shaft. The opening and closing degree of the full-automatic centrifuge can be obtained by obtaining the magnetic induction angle sensor during specific application. In the full-automatic production line, the outer cover is only in a full-open state and a full-closed state, so that the cover 3 is also provided with an outer cover opening limit switch and an outer cover closing limit switch. The opening limit switch and the closing limit switch of the outer cover body can adopt a direct-acting limit switch, a roller type limit switch or a microswitch type travel limit switch.

The vibration igniting unit of the automatic vibration igniting machine for the centrifuge bottle as shown in fig. 2 comprises: a driving mechanism 4, a point vibration eccentric disc 5 and a centrifugal bottle clamp 6.

The drive mechanism 4 has an output shaft that outputs a rotational torque. In some embodiments, if the driving mechanism is applied to a non-automatic scenario, the driving mechanism 4 may be any motor capable of driving the output shaft to rotate, such as a stepping motor, a single-phase motor, or the like. When the cell vibration detection device is applied to an automatic production line, servo motors are selected for driving according to the cell point vibration characteristics, and each servo motor is provided with a zero position switch so as to facilitate a machine arm to accurately place a centrifugal bottle; meanwhile, the power of the servo motor is selected to be 50w to 1000w, and is preferably 100w in order to adapt to cell production. During specific installation, the driving mechanism 4 can be suspended below the point vibration substrate 7 by adopting a bracket, and the point vibration substrate 7 provides a basic supporting force for the driving mechanism 4.

The point vibration eccentric disc 5 is arranged at the output end of the output shaft in an eccentric mode and rotates by taking the output shaft as an axis; the eccentric mode is defined as that the axis of the point vibration eccentric disc 5 and the axis of the output shaft are arranged in parallel and have a set distance. In some embodiments, in particular applications, the vibration eccentric disc 5 is mounted at the output end of the output shaft through a crankshaft; the output shaft drives the crankshaft to rotate through a coupler. In order to avoid cell damage caused by excessive vibration, the distance between the axis of the main shaft 9 of the crankshaft and the axis of the crank 8 is 0.1mm-10mm as shown in fig. 3. The dimensions are set according to the specific centrifuge bottle size.

Preferably, in order to realize that the eccentric disc 5 eccentrically rotates around the output shaft, the main shaft 9 of the crankshaft is mounted on a vibration base plate 7 (i.e. the vibration base plate 7) through a bearing, and the vibration base plate 7 provides an integral supporting force for the vibration unit. The crank 8 is mounted on the eccentric disc 5 by another bearing. In order to avoid the eccentric disc 5 from rotating relative to the crank 8, the bottom of the eccentric disc 5 can be connected to the inner wall of the shell of the automatic point vibration machine of the centrifugal bottle through an elastic element; or the bottom of the point vibration eccentric disc 5 can be connected to the point vibration base plate 7 through an elastic element; or when a plurality of point vibration units are arranged, the point vibration units are uniformly distributed, and the adjacent two point vibration eccentric discs 5 are elastically connected by a spring. In order to facilitate the elastic connection, the bottom of the point vibration eccentric disc 5 is provided with an elastic element connecting part. The elastic connection mainly realizes that the eccentric disc 5 does not rotate relative to the axis of the eccentric disc in the point vibration process, and only rotates along with the crankshaft in a circle. Meanwhile, the point vibration effect can be enhanced through elastic connection, and particularly when the driving mechanism 4 is started to rotate, the point vibration eccentric disc 5 is driven by the crankshaft and can vibrate for the first time due to elastic resistance of the elastic element.

The centrifugal bottle clamp 6 is arranged on the point vibration eccentric disc 5 in a mode of having elastic freedom degree in the axial direction relative to the point vibration eccentric disc 5; by definition, the axial direction is a direction parallel to the axis of the output shaft.

In some embodiments, a prior art centrifuge bottle holder 6 capable of performing this function may be used. The technical scheme that the centrifuge bottle clamp 6 is provided with a base 61, a centrifuge bottle supporting seat 62 and an elastic clamping piece 63; the centrifuge bottle supporting seat 62 is integrally arranged on the base 61, and the upper surface part of the centrifuge bottle supporting seat is recessed to form a bottom positioning part (generally in an inverted cone structure) matched with the bottom of the centrifuge bottle; the elastic clamping member 63 has a plurality of columns and at least one auxiliary ring 65; one end of each of the plurality of columns surrounds the centrifuge bottle support base 62 and is fixed on the base 61 to form a centrifuge bottle side surface clamping structure (the size of the centrifuge bottle side surface clamping structure is matched with that of the centrifuge bottle), and the other end of each column is reversely bent to form a reinforcing ring 64; the auxiliary ring 65 surrounds all the columns and connects the lower portions of all the columns. During the specific use, the robotic arm inserts the centrifuge bottle into centrifuge bottle side clamping structure, and in the process of the shake, the inward face of the reinforcing ring 64 will produce a clamping force on the bottleneck of the centrifuge bottle. Meanwhile, the annular body is used as the reinforcing ring 64, so that the clamping strength can be effectively ensured, and the centrifugal bottle is prevented from falling off in the point vibration process.

Preferably, in order to reduce the overall weight, the base 61 is formed by a ring-shaped support and a plane surface supported by the ring-shaped support, the plane surface is provided with a projection, the surface part of the projection is sunken relative to the projection to form the bottom positioning part of the bottom of the centrifuge bottle, and the projection and the bottom positioning part of the bottom of the centrifuge bottle together form the centrifuge bottle supporting seat 62. This kind of structure guarantees base 61 with centrifuge bottle supporting seat 62 can integrated into one piece, saves the cost to reduce some shake machine self weight.

In order to realize that the centrifugal clamp has an elastic degree of freedom in the axial direction relative to the point vibration eccentric disc 5, the method is mainly realized by the following steps:

first, the bases 61 of the centrifuge bottle jigs 6 are connected by rubber sheets or disc springs made of rubber.

Secondly, a plurality of through holes can be annularly distributed on the point vibration eccentric disc 5, and guide pins with protruding parts are distributed along the through holes. One end of the guide pin is fixed at the bottom of the centrifugal bottle clamp 6, and the other end of the guide pin penetrates through the through hole and is limited by the protruding part of the guide pin. Meanwhile, a spring is arranged on the guide pin at the section between the bottom of the centrifugal bottle clamp 6 and the point vibration eccentric disc 5.

The two ways described above achieve that the centrifuge bottle holder 6 has one degree of freedom in the axial direction with respect to the shaking eccentric 5.

In some embodiments, to assist the operation of the robotic arm, a detection device is provided on each centrifuge bottle holder 6 to detect whether a centrifuge bottle is carried on the centrifuge bottle holder 6. The detection device adopts a gravity sensor or a photoelectric sensor. When the gravity sensor is adopted, the gravity sensor is arranged at the bottom positioning part at the bottom of the centrifugal bottle. When a photoelectric sensor is adopted, the photoelectric sensor is arranged on the base 61, and the height of the photoelectric sensor ensures that the centrifuge bottle is positioned on a photoelectric detection path of the photoelectric sensor.

Such as the integration of multiple seismic units as shown in fig. 4. In order to realize batch centrifugation, the multi-point vibration unit can be integrated.

In the integration process, because each point shakes the unit and will produce an independent vibrations, can make the automatic point of centrifugal flask shake machine wholly have big amplitude. In order to overcome the technical defects, the method adopts the following two modes during design.

Firstly, the integral design is that the automatic point vibration machine for the centrifugal bottles is provided with an outer protection device (namely an outer shell), and the outer protection device is provided with a centrifugal bottle placing table and a centrifugal bottle point vibration area which are adjacently arranged; the point vibration unit is arranged in the point vibration area of the centrifugal bottle through a point vibration substrate 7. Place the unification structure in platform and centrifugal flask point vibration district through the centrifugal flask, reduce the equipment vibrations that the centrifugal flask vibrates and bring by a wide margin.

Secondly, a plurality of point vibration units are uniformly distributed and supported by a point vibration substrate 7; the point vibration eccentric disc 5 in the point vibration unit is arranged on the crankshaft through a bearing, and the two adjacent point vibration eccentric discs 5 are elastically connected. Meanwhile, when the servo motor is in the zero position, the eccentric disc 5 of any adjacent two point vibration units in each point vibration unit has different initial rotation angles (the rotation angle of the eccentric disc 5 relative to the zero position is the zero position by taking one position of the crank 8) and the initial angles of the eccentric disc 5 of each point vibration unit are designed in a symmetrical mode (as shown in fig. 5). That is, when a plurality of point vibration units are designed side by side, the point vibration eccentric discs 5 of the two point vibration units arranged side by side have symmetrical initial angles, and can always keep the angle symmetry in the using process (if one of the two point vibration eccentric discs 5 arranged side by side rotates 60 degrees forwards relative to the zero position, and the other rotates 60 degrees backwards). The oscillation phase difference change in the oscillation process brought by the deviation of the initial angle is utilized, and finally all oscillation phases can be mutually compensated and offset, so that the whole oscillation is balanced, and the vibration of the automatic vibration machine of the centrifugal bottle is reduced.

Although the present invention has been described with reference to the preferred embodiments, it is not intended to be limited thereto. Those skilled in the art can make various changes and modifications without departing from the spirit and scope of the invention. Therefore, the protection scope of the present invention should be determined by the appended claims.

Claims

1. The utility model provides an automatic point of centrifugal flask shakes machine which characterized in that, includes the point and shakes the unit, the point shakes the unit and includes:

a drive mechanism having an output shaft that outputs a rotational torque;

2. The automatic vibration igniting machine for centrifugal bottle as claimed in claim 1, wherein said eccentric disk is mounted to the output end of said output shaft via a crankshaft; the output shaft drives the crankshaft to rotate through a coupler.

3. An automatic jar lighter according to claim 2, wherein the eccentric disk is mounted on the crankshaft via a bearing, and the eccentric disk is elastically connected to the inner wall of the shell of the automatic jar lighter.

4. The automatic vibration igniting machine for centrifugal bottles of claim 1, wherein the number of vibration igniting units is several, and the several vibration igniting units are uniformly distributed; the point vibration eccentric discs in the point vibration unit are mounted on the crankshaft through bearings, and the adjacent two point vibration eccentric discs are elastically connected.

5. The automatic point vibration machine for centrifugal bottles of claim 1 wherein there are several point vibration units, the point vibration eccentric discs in any adjacent two point vibration units in each point vibration unit have different initial rotation angles, and the initial angles of the point vibration eccentric discs in each point vibration unit are designed symmetrically.

6. The automatic jar lighter according to claim 1, wherein the jar has a base, a jar support base and a resilient clamp; the centrifuge bottle supporting seat is integrated on the base, and the upper surface part of the centrifuge bottle supporting seat is sunken to form a bottom positioning part matched with the bottom of the centrifuge bottle; the elastic clamping piece is provided with a plurality of upright posts and at least one auxiliary ring; one end of each upright column surrounds the centrifuge bottle supporting seat and is fixed on the base to form a centrifuge bottle side surface clamping structure, and the other end of each upright column is bent reversely to form a reinforcing ring; the auxiliary ring surrounds all the upright posts and is connected with the lower parts of all the upright posts.

7. The automatic vibration machine for the centrifugal bottle as claimed in claim 1, further comprising a plurality of guide pins with protrusions, wherein a plurality of through holes are annularly distributed on the eccentric disk for vibration, one end of each guide pin is fixed at the bottom of the clamp for the centrifugal bottle, and the other end of each guide pin is limited by the protrusion of the guide pin after penetrating through the through hole; meanwhile, a spring is arranged on the section of the guide pin, which is positioned between the bottom of the centrifugal bottle clamp and the point vibration eccentric disc.

8. An automatic jar lighter according to claim 1, wherein the drive mechanism is provided with a zero setting device.

9. The automatic centrifugal bottle vibration igniting machine according to claim 1, further comprising an outer protecting device, wherein the outer protecting device is provided with a centrifugal bottle placing table and a centrifugal bottle vibration igniting area which are adjacently arranged; the point vibration unit is arranged in the point vibration area of the centrifugal bottle through a point vibration substrate.

10. The automatic vibration machine for centrifugal bottles of claim 9, wherein a cover is arranged above the centrifugal bottle vibration unit in the centrifugal bottle vibration area, an automatic cover opening mechanism is arranged on the cover, and the cover is in contact with the top of the centrifugal bottle carried by the centrifugal bottle vibration unit when the cover covers the centrifugal bottle vibration unit.