CN113274439A

CN113274439A - Traditional Chinese medicine composition for treating liver diseases and application thereof

Info

Publication number: CN113274439A
Application number: CN202110557155.5A
Authority: CN
Inventors: 李宝鸿; 李佳潞
Original assignee: Mengzi Hongcheng Hospital
Current assignee: Mengzi Hongcheng Hospital
Priority date: 2014-07-01
Filing date: 2014-07-01
Publication date: 2021-08-20
Also published as: CN105287927A

Abstract

The invention relates to a traditional Chinese medicine composition for treating liver diseases and application thereof, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 1 part of swertia mileensis, 0.4-0.7 part of oriental wormwood, 0.4-0.7 part of astragalus root, 0.3-0.6 part of verbena, 0.2-0.5 part of dyers woad leaf, 0.1-0.2 part of bupleurum root, 0.1-0.2 part of ganoderma lucidum, 0.02-0.08 part of scutellaria root and 0.01-0.04 part of gentian. The invention has the effects of strengthening body resistance and eliminating evil, clearing heat and promoting diuresis, clearing liver and gallbladder damp-heat and purging liver and gallbladder damp-heat, and can treat liver diseases by reducing the content of one or more of glutamic-pyruvic transaminase, glutamic-oxalacetic transaminase and direct bilirubin. The preparation formulation of the invention comprises a tea preparation, a capsule and a tablet, the tea preparation is drunk after being soaked in boiling water, the soup color is brown and yellow, the taste is slightly sweet, and the taste is mild. General hepatic injury can be recovered after drinking the tea for 3-5 days; patients with glutamate pyruvate transaminase up to 1000 or more return to normal values one month.

Description

Traditional Chinese medicine composition for treating liver diseases and application thereof

The application is a divisional application with application date of 2014 07, 01, application number of 201410326602.6 and invention name of 'a Chinese medicinal composition for treating liver diseases'.

Technical Field

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating liver diseases and application thereof. The trade names are liver-benefiting powder, liver-clearing toxin-expelling soup and the like.

Background

The basic understanding of the traditional Chinese medicine on the occurrence of liver diseases is as follows: the medicine can be used for treating acute icterohepatitis, chronic persistent hepatitis, liver cirrhosis, hepatic ascites, alcoholic hepatitis, fatty liver, hepatitis B, transaminase increase, etc., or diseases caused by affection of exogenous wind-heat, fatigue, weakness, virus invasion to liver and defense, damp-heat imbalance, menstrual blood obstruction, and impaired liver function; or the liver and spleen can be affected by damp-heat and toxic pathogen due to frequent excessive drinking and pungent irritation.

The traditional Chinese medicine is mainly used for treating liver diseases by eliminating causes, relieving symptoms and promoting the regression of focus, and the traditional Chinese medicine generally adopts the methods of strengthening body resistance and eliminating evil, clearing heat and promoting diuresis, clearing liver and gallbladder damp-heat, purging liver and gallbladder damp-heat, promoting blood circulation and dredging channels, diminishing inflammation and detoxifying, inducing diuresis and relieving swelling, and treating the liver and spleen by promoting blood circulation, clearing liver and gallbladder damp-heat and soothing liver and strengthening spleen.

The above traditional Chinese medicine theory points out the general pathogenesis and treatment principle, but cannot replace the specific traditional Chinese medicine formula. The existing liver disease medicines in the market are various in names and may have various characteristics, but no medicine with extremely strong effect appears all the time, so that further exploration is needed, and new preparations are continuously provided to meet the changing requirements of liver disease treatment.

Disclosure of Invention

The invention aims to provide a novel traditional Chinese medicine composition for treating liver diseases, which is characterized by strengthening body resistance and eliminating evil, clearing heat and promoting diuresis, clearing damp-heat in liver and gallbladder and purging damp-heat in liver and gallbladder, is used for treating diseases such as acute icterohepatitis, chronic persistent hepatitis, cirrhosis, hepatic ascites, alcoholic hepatitis, fatty liver, hepatitis B, transaminase increase and the like, has quick response, good curative effect and high cure rate, and can be used for preventing and treating liver cancer and other diseases.

The invention provides a traditional Chinese medicine composition for treating liver diseases, which is a powdery composition prepared by mixing the following medicinal herbs in parts by weight:

1 part of swertia mileensis, 0.4-0.7 part of oriental wormwood, 0.4-0.7 part of astragalus root, 0.3-0.6 part of verbena, 0.2-0.5 part of dyers woad leaf, 0.1-0.2 part of bupleurum root, 0.1-0.2 part of ganoderma lucidum, 0.02-0.08 part of scutellaria root and 0.01-0.04 part of gentian.

The more suitable proportioning relation is as follows:

1 part of swertia mileensis, 0.53 part of oriental wormwood, 0.53 part of astragalus root, 0.5 part of verbena, 0.37 part of dyers woad leaf, 0.17 part of bupleurum root, 0.13 part of ganoderma lucidum, 0.067 part of scutellaria baicalensis and 0.033 part of gentian.

The fineness of the composition is more than 60 meshes.

The composition is packaged into small bag of 10 g/bag with tea bag paper, and can be used as medicinal tea for drinking after being infused with boiling water. The content of the tea bag is yellow-brown bag powder, and the taste is slightly sweet.

The composition can also be made into capsule or tablet.

0.1-0.2 part of pseudo-ginseng can also be added into the formula so as to aim at severe patients with liver ascites.

Even 0.1-0.2 part of ophiorrhiza pumila can be added, and the addition of the medicine has obvious curative effect on treating serious liver injury.

The medicinal materials are all calculated according to dry weight.

The application and dosage of the tea preparation are as follows: can be used as tea. The medicine bag is soaked in boiling water for 5-10 min, or boiled for 5 min. Adult 30g (three small bags) per day. The children are halved.

The dosage for use as capsules or tablets is as follows:

each granule or tablet contains 0.4g of medicinal powder, and is taken with boiled water, and 4-6 granules (tablets) are taken by adults three times per day. The child takes the appropriate or follow the medical advice.

The tablet is prepared by adding proper starch and pressing according to the common process. The capsule shell has certain side effects, and the composition of the invention is slightly bitter and can be accepted by most patients, so that the use of tablets is hard to try.

The preparation formulation of the invention takes the tea as the main component and takes the capsules and tablets as the auxiliary components. The patients take the tea just like drinking tea at ordinary times, the small bag of the medicine bag is put into a cup, and the tea is soaked in boiled water for drinking, so that the tea is very convenient, the soaked soup is brownish yellow, the taste is slightly sweet, and the taste is generally accepted easily.

The invention strengthens the body resistance to eliminate pathogenic factors, clears heat and promotes diuresis, clears liver and gallbladder damp-heat and purges liver and gallbladder damp-fire. Can be used for treating acute icterohepatitis, chronic persistent hepatitis, liver cirrhosis, hepatic ascites, alcoholic hepatitis, fatty liver, hepatitis B, and transaminase increase, and can also be used for preventing and treating hepatocarcinoma. The specific clinical use effect is as follows:

general hepatic injury can be recovered after drinking the tea for 3-5 days; the tea is especially effective for patients with elevated glutamic-pyruvic transaminase, and can recover to normal value after drinking for one month for patients with index above 1000; fatty liver patients can be cured after drinking for 3 months, and symptoms completely disappear; acute liver injury is cured for one week.

It is especially effective for fulminant hepatitis such as acute icterohepatitis, and can be cured in 7-15 days. For the places such as army and school where the crowd is concentrated, the diseases can be quickly controlled and cured when the diseases occur. Has important significance for maintaining and recovering the battle effectiveness of the troops. The raw materials of the composition of the invention are available in situ when the wartime own prescription is restricted or blocked. The method is very beneficial to breaking blockade and controlling enemy wins, thereby relating to the great national defense benefit of the country.

Detailed Description

The positive effects of the present invention are further illustrated in the following clinical cases using the tea and tablet formulations of the present invention in a military division hospital. The medicine for each case is called liver benefiting powder for short, and is a tea preparation, and the medicine components, the packaging specification and the preparation method are as follows:

the preparation method comprises the following steps: pulverizing the raw materials, mixing, sieving with 60 mesh sieve, and packaging into tea bags.

The tea preparation is a first tea preparation.

500g of pseudo-ginseng and 500g of ophiorrhiza pumila are added on the basis of the formula I. The preparation method and packaging specification are unchanged, and the formula is No. two tea.

The capsule and the tablet are marked as a first capsule (or tablet) and a second capsule (or tablet) according to the proportion relation.

Clinical cases:

1. zhongnan Jianshui county patient in Zhonghua, a woman, 63 years old. Patients had poor spirit, emaciation, enlarged abdomen, swollen lower limbs and scanty and yellow urine for 3 years. The patients come to the regional hospital to see the doctor in 9 months in 1995, and the tongue of the patient is red, the tongue coating is yellow and greasy, and the pulse is wiry and rapid. Physical examination: dark and gloomy complexion, slight yellow staining of sclera, no abnormalities of heart and lung, abdominal distension, varicose veins of abdominal wall, edema of both lower limbs. Five hepatitis B HBsAg (ten), HBeAb (ten) and HBcAb (ten), and the DNA detection result is positive; liver function glutamic-pyruvic transaminase (ALT)179U/T (normal 0-40), glutamic-oxalacetic transaminase (AST)115U/L (normal 0-40), Total Bilirubin (TBIL)34.8 μmol/L, Albumin (ALB)32 g/L; type B ultrasonography shows liver cirrhosis, splenomegaly and massive ascites. And (3) diagnosis: viral hepatitis (type b) cirrhosis (decompensated) ascites. The liver-benefiting powder second tea is taken 30-50 g (1 small bag 10g) per day and is drunk as tea, and the effect is better when the tea is soaked in boiling water for 5-10 minutes or boiled for 5 minutes. After taking the medicine for 3 courses of treatment (1 month is 1 course of treatment), the symptoms of improved spirit, increased appetite, hypodynamia, abdominal distension, edema of both lower limbs and the like are relieved. After the liver benefiting powder is continuously taken home for 4 treatment courses, the albumin is improved, the ascites is subsided, the liver function is obviously improved, the alanine transaminase (ALT) is 65U/T, the aspartate Aminotransferase (AST) is 52U/L, the Total Bilirubin (TBIL) is 22.8 mu mol/L, and the Albumin (ALB) is 41 g/L.

In the following cases, patients with liver cirrhosis and liver ascites all take the liver-benefiting powder A-II tea, and the rest is the liver-benefiting powder A-II tea.

2. Yunnan Pink patient, woman, 59 years old. In 1995, symptoms such as fever, malaise, asthenia, anorexia, nausea, emesis, right upper abdomen discomfort, and jaundice appear in 3 months. The patients are diagnosed in a regional hospital 12 months in 1995, and the body is found to be yellow in skin and sclera, yellow in urine, high in direct bilirubin concentration, positive in bilirubin and urobilinogen, 2cm below the hepatic rib, soft in quality, tender in touch and percussion pain, swollen in liver and spleen, and diagnosed as acute icteric hepatitis. The liver-benefiting powder is administered after returning home, and the dosage is the same as that in example 1. After 10 days, jaundice and other symptoms gradually subside, the spirit and appetite are obviously improved, the liver and spleen gradually retract, the tenderness and the percussion pain are obviously relieved, and the liver function is recovered to be normal.

3. Shipingxian county of Yunnan province, a certain history, women, 51 years old. The patients were examined at the young age and were carriers of hepatitis B virus. In 1996, in 1 month, pain in the liver region, abdominal distention, chest distress, edema, abdominal pain, lower limbs urine, short breath, and asthenia were observed. In 1996, 6 months, the patients came to a regional hospital and were diagnosed with cirrhosis. The liver-benefiting powder is administered with the same dosage as in example 1. After taking for 3 months, the subjective symptoms gradually improve, and the physical condition is good. Blood test shows that glutamic-pyruvic transaminase (ALT) and Direct Bilirubin (DBIL) are obviously reduced; after taking the liver tonifying powder for 4 months, the mental state is obviously improved, the pain of the liver area disappears, the edema is subsided, the liver function is recovered to be normal, and the vital signs are stable.

4. The patient in Jianshui county of Yunnan province is male, 49 years old. Chronic icteric hepatitis with symptoms of inappetence, nausea, vomiting, aversion to oil, liver pain, asthenia, fever, jaundice, etc. In 1996, 12 months, the physician visits the regional hospital to take the liver-benefiting powder, and the dosage and administration are the same as example 1. After 1 month of administration, the subjective symptoms gradually improved, and the physical condition was good. Blood tests show that glutamic-pyruvic transaminase (ALT) and direct bilirubin (TBIL) are reduced obviously. After 2 courses of administration of the liver benefiting powder, the glutamic-pyruvic transaminase is reduced from 425U/L (ALT) to 115U/L (ALT) before the liver benefiting powder is taken, and the direct bilirubin is reduced from 77 mu mol/L (TBIL) to 36 mu mol/L (TBIL). After the liver benefiting powder is taken for 75 days, the mental state is obviously improved, the pain of the liver area disappears, the liver function is recovered to be normal, and the vital signs are stable.

5. Yunan Wenshan patient Kangchi, male, 41 years old. Since drinking a large amount of alcohol for a long time, hepatitis B is suffered more than ten years ago, and the treatment in a plurality of hospitals is ineffective. In 1997 for 2 months, the ascites due to cirrhosis is obviously aggravated, and in three months after lying in bed, the patient suffers from nausea, fatigue, hypodynamia, edema of lower limbs, diarrhea, abdominal pain, abdominal distension and other symptoms, and the mental status is very bad. After the local symptomatic treatment is carried out for more than 1 month, the symptoms can not be controlled all the time, the patient can arrive at a regional hospital for treatment immediately, the hospital carries out comprehensive examination on the symptoms, the B ultrasonic shows hepatosplenomegaly, the liver function tests show positive HBsAg, the alanine transaminase (ALT) is 825U/L, a large number of liquid dark areas in the abdominal cavity and ascites compression symptoms are obvious, and the liver cirrhosis caused by viral hepatitis is diagnosed. Ascites is eliminated by ascites concentration and reinfusion, so that ascites pressure is relieved. The liver-benefiting powder is administered with the same dosage as in example 1. After taking the medicine for 3 months, abdominal distension and abdominal pain are relieved, edema of lower limbs is relieved, B-ultrasonic shows that the liver is large, echo is uneven, a small amount of liquid dark areas are formed in the abdominal cavity, and the condition of the patient is improved when the patient comes soon. After the patient is discharged from hospital, the patient continues to take the liver tonifying powder, and after 5 months of taking the liver tonifying powder, the hospital rechecks, the abdominal distension of the patient disappears, the mental state is obviously improved, the texture becomes soft, the ascites disappears, the liver function is recovered to be normal, and the vital signs are stable.

6. A patient in Yunnan Kunming city is Tan somebody, male, 56 years old. The patients were found to have three positive signs of hepatitis B on physical examination in month 1 of 1995. The patients have not been well treated by taking a lot of liver-protecting medicines, and obvious symptoms such as liver pain, nausea, vomiting and the like appear. In 1997 for 5 months, the symptoms of dark face, edema of lower limbs, poor spirit, abdominal distension, diarrhea, unstable walking and the like appear. Then the patient goes to the regional hospital for treatment. Then, the liver function was examined: glutamic-pyruvic transaminase (ALT)139U/L, glutamic-oxalacetic transaminase (AST)78U/L, Total Bilirubin (TBIL)40 μmol/L, Direct Bilirubin (DBIL)30 μmol/L; b, hepatitis B virus DNA detection: 1.2X 10⁶(ii) a B, ultrasonic wave: the liver has normal size and shape, uneven surface, rough internal echo, enlarged spleen volume, thickness of about 52mm and uniform internal echo. And (3) diagnosis: ascites due to cirrhosis of the three major positive of hepatitis B.

After one week of treatment with the liver-tonifying powder in hospitals, the liver-tonifying powder with 6 months old is taken home, and the usage and dosage are the same as in example 1. After being taken for 6 treatment courses, the ascites symptoms are obviously improved, the hepatitis B virus number is obviously reduced and is less than 1.2 multiplied by 10³Normal liver function and stable disease condition.

7. A patient in Yuxi city of Yunnan province tries to get a certain time, and the male is 50 years old. Patients are drunk, like eating greasy food, and have fat body. Epigastric discomfort, poor appetite, weakness and aggravated postprandial nausea after 2 months in 1997. In 1997, the doctor visits the regional hospital 10 months, and no abnormality occurs in the heart and lung; laboratory examination: blood, urine and stool are normal; liver function examination: glutamic-pyruvic transaminase (ALT)69U/L, glutamic-oxalacetic transaminase (AST)43.6U/L, Total Bilirubin (TBIL)51.5 μmol/L, Direct Bilirubin (DBIL)18 μmol/L, hepatitis B two-to-half negative test, and the rest normal test. The transaminase is diagnosed to be increased (chronic alcoholic liver injury), and the liver-benefiting powder is taken with the same dosage as in example 1. After 1 month, the indexes tend to be normal, the glutamic-pyruvic transaminase (ALT) is 36U/L, the glutamic-oxaloacetic transaminase (AST) is 34.1U/L, the Total Bilirubin (TBIL) is 39.5 mu mol/L, the Direct Bilirubin (DBIL) is 11.9 mu mol/L, the symptoms disappear, and the appetite is enhanced.

8. The old city of Yunnan province is a certain patient, women, 62 years old. Can be used for treating liver cirrhosis. In 1997, abdominal pain appeared in 7 months, and the part under xiphoid process showed persistent distending pain discomfort, accompanied by abdominal distension discomfort, vomiting, fever, black stool, edema of lower limbs and other symptoms. In 1997 8 months, visit to regional hospitals, B-mode ultrasound suggested: cirrhosis, splenomegaly, ascites. Upper abdomen CT prompt: liver cirrhosis, splenomegaly, ascites, and focus of the left side of the liver. Three pairs of hepatitis B examinations suggest: HBsAg +, HBcAb +. The liver-benefiting powder is administered with the same dosage as in example 1. After taking the medicine for 4 months, the subjective symptoms gradually improve and the physical condition is improved. After taking the medicine for 4 months again, the mental state is obviously improved, the pain of the liver area basically disappears, the edema is subsided, the liver function is recovered to be normal, and the vital signs are stable.

9. Yuan of a certain patient in Yun nan Hekou county, male, 55 years old. Drinking 0.5-1 kg of white spirit every day for more than 30 years, causing hypodynamia, cold sweat and hand tremor in 12 months in 1996, and eating only a small amount of porridge and soup food every day. Poor sleep and aggravated hand tremor when no alcohol is drunk, and the symptoms are relieved after alcohol drinking, and the symptoms are slightly improved after the treatment in local hospitals. And then, the alcoholism is continued, and the symptoms are repeated. In 1997, symptoms such as systemic hypodynamia, hand tremor and the like are aggravated in 4 months, the appetite is poor, the food consumption of three meals is obviously reduced, and the vomit is mostly yellow water-like substances accompanied by oil aversion, nausea and vomiting. The diagnosis is carried out in a regional hospital in 8 months in 1997, and the liver function is examined to prompt 107U/L of glutamic-pyruvic transaminase (ALT), 96U/L of glutamic-oxalacetic transaminase (AST) and 1082U/L of glutamyl transpeptidase (GGT) to diagnose the chronic alcoholic hepatitis. The liver-benefiting powder is administered with the same dosage as in example 1. After taking the medicine for 3 months, the disease condition is relieved. After continuously taking the medicine for 4 months, the biochemical indexes of blood are normal, the glutamic-pyruvic transaminase (ALT) is 37U/L, the glutamic-oxaloacetic transaminase (AST) is 36U/L, and the condition is stable.

10. Yunan province, Mengyuan, Shang, male, 41 years old. The patient often has a small amount of bleeding of gum, and the big three positive of hepatitis B are detected during the later physical examination. In 1997 for 8 months, patients have no inducement to abdominal pain and distending pain, and have gradually worsened abdominal distension and edema of both lower limbs, increased stool frequency, and cirrhosis and ascites as the result of local hospital diagnosis. Then go to a regional hospital for treatment. Five items of hepatitis B were examined: HBsAg (+) HBeAg (+) HBcAb (+). Liver function: alanine Aminotransferase (ALT) is 160U/L, aspartate Aminotransferase (AST) is 178U/L. Color Doppler ultrasound: portal vein 1.3 cm; spleen thickness 5.3 cm; splenic vein 1.3 cm; the liquid in the abdominal cavity is 11.3 cm. The liver-benefiting powder is administered with the same dosage as in example 1. After taking the medicine for 3 months, the subjective symptoms are improved. After taking the liver-benefiting powder for 3 months, the patient can return to normal liver function, the ascites disappears, and all indexes of the patient return to normal with good spiritual outlook.

11. The male is 66 years old, whichever one of patients in Jianshui county in Yunnan province. Usually, people like drinking wine and are fat. Patients in 3 months in 1997 have obvious discomfort symptoms, such as loss of appetite, fatigue, oil intolerance, abdominal distension and sometimes dull pain in the liver region. The result is fatty liver, which is seen in the regional hospital in 9 months 1997, with mild abnormal liver function, 91.6U/L glutamate pyruvate transaminase (ALT) and 33.8. mu. mol/L Total Bilirubin (TBIL), which is alcoholic fatty liver. The liver-benefiting powder is administered with the same dosage as in example 1. After 1 month of administration, the disease condition was relieved. After the medicine is continuously taken for 1 month, the biochemical indexes of the blood are normal, the alanine Aminotransferase (ALT)38U/L and the Total Bilirubin (TBIL)18.8 mu mol/L, and the color Doppler ultrasound indicates that the parenchyma echo of the liver is uniform, the imaging of the fatty liver disappears and no relapse occurs.

12. Yunan old city patient, male, is aged 55 years. In 1998, symptoms such as fever, malaise, hypodynamia, anorexia, nausea, vomiting, right upper abdomen discomfort, jaundice and the like appear in 2 months. The patient is diagnosed in a subarea hospital 9 months in 1998, and the patient is found to have yellow skin and sclera, yellow urine, directly increased bilirubin concentration, positive bilirubin and urobilinogen, soft 2cm below the hepatic rib, tenderness and percussion pain, hepatosplenomegaly and acute icteric hepatitis. The liver-benefiting powder is administered after returning home, and the dosage is the same as that in example 1. After 10 days of taking, jaundice and other symptoms are gradually eliminated, the spirit and appetite are obviously improved, the liver and the spleen are gradually retracted, the tenderness and the percussion pain are obviously relieved, and the liver function is recovered to be normal.

13. Some patients, male, 45 years old, in Yunnan Tonghai. Since drinking a large amount of alcohol for a long time, hepatitis B is suffered more than ten years ago, and the treatment in a plurality of hospitals is ineffective. In 1998, the ascites due to cirrhosis became worse in 4 months, and the patients were bedridden for two months, with symptoms of nausea, fatigue, asthenia, edema of lower limbs, diarrhea, abdominal pain, abdominal distension, etc., and the mental condition was very bad. After the local symptomatic treatment is carried out for more than 1 month, the symptoms can not be controlled all the time, the local symptomatic treatment is carried out in a regional hospital for treatment, the body B ultrasonic examination shows that the liver and spleen are enlarged, the liver function is positive to the hepatitis B surface antigen, the alanine Aminotransferase (ALT) is 765U/L, a large amount of liquid dark areas in the abdominal cavity and ascites compression symptoms are obvious, and finally the cirrhosis caused by the viral hepatitis is diagnosed. Ascites is eliminated by ascites concentration and reinfusion, so that ascites pressure is relieved. The liver-benefiting powder is taken simultaneously, and the usage and the dosage are the same as in example 1. After taking the medicine for 3 months, abdominal distension and abdominal pain are relieved, edema of lower limbs is relieved, B-ultrasonic shows that the liver is large, echo is uneven, a small amount of liquid dark areas are formed in the abdominal cavity, and the condition of the patient is improved when the patient comes soon. After the patient is discharged from hospital, the liver-benefiting powder is continuously taken, and the patient is rechecked after taking for 5 months, so that the abdominal distension disappears, the mental state is obviously improved, the texture becomes soft, the ascites disappears, the liver function is recovered to be normal, and the vital signs are stable.

14. The old city of Yunnan patients, named as Gobi, are 69 years old. Drinking 0.5-1 kg of white spirit every day for more than 40 years, causing hypodynamia, cold sweat and hand tremor in 10 months in 1997, and eating a small amount of porridge and soup food every day. Poor sleep and aggravated hand tremor when no alcohol is drunk, and the symptoms are relieved after alcohol drinking, and the symptoms are slightly improved after the treatment in local hospitals. And then, the alcoholism is continued, and the symptoms are repeated. Symptoms such as systemic debilitation, hand tremor, etc. aggravate in 1998 for 6 months, poor appetite, and significantly reduced food consumption for three meals, accompanied by oil aversion, nausea and vomiting, and most vomit is yellow water sample. After 8 months in 1998, the patients are treated in a regional hospital, and the liver functions are checked to show that glutamic-pyruvic transaminase (ALT)97U/L, glutamic-oxalacetic transaminase (AST)92U/L and glutamyl transpeptidase (GGT)1062U/L, so that the patients are diagnosed as chronic alcoholic hepatitis, and the liver-benefiting powder is taken, and the using amount is the same as that in example 1. After taking for 1 month, the disease condition is relieved. After continuously taking for 3 months, the indexes of blood biochemistry are normal, glutamic-pyruvic transaminase (ALT)40U/L and glutamic-oxaloacetic transaminase (AST)34U/L, and the disease condition is stable.

15. The patient in the city of Yunnan province, child and woman, 29 years old. Chronic icteric hepatitis with symptoms of inappetence, nausea, vomiting, aversion to oil, liver pain, asthenia, fever, jaundice, etc. In 1998, in 12 months, the physician visits the regional hospital and takes the liver-tonifying powder with the same usage and dosage as example 1. After taking the medicine for 2 months, the subjective symptoms are improved. Blood test shows that glutamic-pyruvic transaminase (ALT) and direct bilirubin (TBIL) are reduced significantly, the intake of glutamic-pyruvic transaminase (ALT) is 725U/L and the intake of direct bilirubin (TBIL) is 127 μmol/L; after the liver-benefiting powder is taken for 3 months, the alanine Aminotransferase (ALT) is 39U/L, and the direct bilirubin (TBIL) is 17 mu mol/L. After the liver benefiting powder is taken for 4 months, the liver function is basically recovered to be normal, the pain of the liver area disappears, and the vital signs are stable.

16. Yunan Wenshan patient Wang, male, age 44. Excessive drinking for more than 20 years, no obvious reasons for oil-deprivation and hypodynamia appear in 1 month in 1999, and no diagnosis and treatment are taken. Vomiting coffee-like gastric contents after drinking in 5 months in 1999, accompanied by dizziness, palpitation, pale complexion, profuse sweat and blurred vision. The Chinese medicinal composition is sent to a regional hospital for treatment by family members, alanine Aminotransferase (ALT)81U/L and aspartate Aminotransferase (AST)57U/L are searched for acute symptoms, alcoholic liver diseases are diagnosed, and the Chinese medicinal composition is taken with the liver-tonifying powder in the same usage and dosage as in example 1. After 1 month of administration, the disease condition was relieved. After the medicine is continuously taken for 2 months, alanine Aminotransferase (ALT) is reduced to 42U/L, aspartate Aminotransferase (AST) is reduced to 41U/L, the disease condition is stable, and the physical condition is good.

17. Yunan Yuanjiang patient is a male with a certain age of 70 years. The patients are subjected to physical examination in the young period, and are hepatitis B virus carriers, no obvious inducement exists in 3 months in 1999, the patients begin to have the conditions of hypodynamia, poor appetite, paroxysmal vague pain in the middle abdomen, slight alleviation of pressing and the like. In 1999, 8 months, visit regional hospitals. Checking alanine Aminotransferase (ALT)180U/L, glutamic-oxaloacetic transaminase (AST)140U/L, Total Bilirubin (TBIL)29.57U/L, Direct Bilirubin (DBIL) 9.64U/L; the B ultrasonic wave indicates the degree III of fatty liver. Non-alcoholic steatohepatitis was diagnosed. The liver-benefiting powder is administered with the same dosage as in example 1. After the medicine is taken for 2 months, the state of illness is relieved, and after the medicine is taken for 3 months, various biochemical indexes are normal and the physical condition is good.

18. A certain Shao in Maitreya county, Yunnan province, female, 57 years old. Hepatitis B is detected at a young age, the treatment effect is poor, hematemesis appears after fatigue of 8 months in 1999, and then a diagnosis is made in a regional hospital. When the liver function is abnormal, the appetite is poor, nausea and vomiting, liver pain and liver function damage are serious, and the liver cirrhosis caused by chronic viral hepatitis B is diagnosed. The liver-benefiting powder is administered with the same dosage as in example 1. After taking the medicine for 3 months, the body condition is improved, and then the liver benefiting powder is taken for 3 months for a return diagnosis, and B ultrasonic examination shows that a plurality of new liver tissues exist in the liver, the liver function is normal, the liver cirrhosis is repaired, and the spirit appetite is obviously improved.

19. The patient in Jianshui county of Yunnan province is aged 62 years old, male. Usually, people like drinking wine and are fat. The patient has obvious discomfort symptoms in 10 months in 1999, such as inappetence, fatigue, oil aversion, abdominal distension and sometimes dull pain in the liver region. The results were fatty liver, which was seen in the regional hospital in 1 month of 2000, with mild abnormality of liver function, glutamic-pyruvic transaminase (ALT)71.6U/L and Total Bilirubin (TBIL) 35.8. mu. mol/L, which was alcoholic fatty liver. The liver-benefiting powder is administered with the same dosage as in example 1. After 1 month of administration, the disease condition was relieved. After the medicine is continuously taken for 2 months, the biochemical indexes are normal, the alanine Aminotransferase (ALT) is 35U/L, the Total Bilirubin (TBIL) is 17 mu mol/L, and the color Doppler ultrasound indicates that the liver parenchyma echo is uniform, the fatty liver imaging disappears, the disease condition is stable, and no relapse occurs.

20. Jia Yi of Yunnan wenshan patient, male, 51 years old. Since long-term heavy drinking, the patient with hepatitis B is detected in the precursor test for over ten years, and the treatment in a plurality of hospitals is ineffective. In 2000, in 4 months, ascites due to cirrhosis becomes worse obviously, and in two months of bed rest, nausea, tiredness, hypodynamia, edema of lower limbs, diarrhea, abdominal pain, abdominal distension and other symptoms are caused, so the mental condition is very poor. After 1 more months of local treatment, symptoms were not controlled. Then the patient comes to a regional hospital for treatment, and is comprehensively checked, the B ultrasonic shows hepatosplenomegaly, the liver function body is positive to hepatitis B surface antigen, the alanine Aminotransferase (ALT) is 965U/L, a large number of liquid dark areas in the abdominal cavity and ascites compression symptoms are obvious, and finally, the liver cirrhosis caused by viral hepatitis is diagnosed. The liver-benefiting powder is administered with the same dosage as in example 1. After taking the medicine for 1 month, abdominal distension and abdominal pain are relieved, edema of lower limbs is relieved, B-ultrasonic shows that the liver is large, echo is uneven, a small amount of liquid dark areas are formed in the abdominal cavity, and the condition of the patient is improved when the patient comes soon. After the patient is discharged from hospital, the liver-benefiting powder is continuously taken, and the patient is rechecked after taking for 5 months, so that the abdominal distension disappears, the mental state is obviously improved, the liver function is recovered to be normal, the texture is soft, the ascites disappears, and the vital signs are stable.

21. Patients in Kunming city county of Yunnan Song Dynasty, women, age 46. The patient was found to have three positive signs of hepatitis B on a 3-month physical examination in 1999. The patients have not been well treated by taking a lot of liver-protecting medicines, and obvious symptoms such as liver pain, nausea, vomiting and the like appear. In 5 months of 2000, the symptoms of dark face, edema of lower limbs, poor spirit, abdominal distension, diarrhea, unstable walking and the like appear. Then the patient comes to a regional hospital for a doctor and the liver function is checked: glutamic-pyruvic transaminase (ALT)169U/L, glutamic-oxalacetic transaminase (AST)98U/L, Total Bilirubin (TBIL)41 μmol/L, Direct Bilirubin (DBIL)33 μmol/L; b, hepatitis B virus DNA detection: 1.2X 10⁸(ii) a B, ultrasonic wave: the liver has normal size and shape, uneven surface, rough internal echo, enlarged spleen volume, thickness of about 52mm and uniform internal echo. And (3) diagnosis: ascites due to cirrhosis of the three major positive of hepatitis B. After one week of treatment, the powder for tonifying liver is taken home with 6 months old, and the usage and dosage are the same as example 1. After 3 months of administration, ascites symptoms are obviously improved, the hepatitis B virus number is obviously reduced to less than 10³The disease condition is basically stable.

22. Some woman in Jianshui county of Yunnan province aged 67 years. Hepatitis B is detected at a young age, the effect is not good all the time after treatment, hematemesis appears after fatigue in 8 months in 2000, and then a diagnosis is made in a regional hospital. When the liver function is abnormal, the appetite is poor, nausea and vomiting, liver pain and liver function damage are serious, and the liver cirrhosis caused by chronic viral hepatitis B is diagnosed. The liver-benefiting powder is administered with the same dosage as in example 1. After the medicine is taken for 1 month, the body condition is improved, and after the medicine is taken for 3 months, the patient can be diagnosed again, and the B-ultrasonic examination shows that a plurality of new liver tissues exist in the liver, the liver function is normal, the liver cirrhosis is repaired, and the spirit and the appetite are obviously improved.

23. Yunnan Qujing City patient hole someone, male, 32 years old. Abdominal distension, diarrhea, yellow water sample excretion for 7-8 times per day, anorexia, yellow body and eyes, edema of lower limbs, no abdominal pain, and fever appear in 8 months in 2000. The doctor visits the hospital in 10 months in 2000 in a subarea, and examines 89U/L glutamic-pyruvic transaminase (ALT), 45U/L glutamic-oxaloacetic transaminase (AST), 23.1g/L Albumin (ALB), 58 mu mol/L Total Bilirubin (TBIL) and 41.1 mu mol/L Direct Bilirubin (DBIL); the upper abdomen CT shows middle-equivalent ascites, and the diagnosis is alcoholic hepatitis. The liver-benefiting powder is administered with the same dosage as in example 1. After taking the medicine for half a month, abdominal distension is relieved, stomach accommodation is improved, and yellow body and eyes, diarrhea and edema of lower limbs are relieved. After the medicine is continuously taken for 1 month, the blood level shows that all indexes are normal and the disease condition is stable.

24. The patient in Yunnan Luchun county is old a certain time, male and 66 years old. Usually, people like drinking wine and are fat. The patient has obvious discomfort symptom in 4 months in 2000, and has no appetite, general debilitation, aversion to oil, abdominal distension and sometimes dull pain in liver region. The patients are seen in the hospital in different areas within 10 months of 2000, the liver function is slightly abnormal, the glutamic-pyruvic transaminase (ALT) is 130.6U/L, the Total Bilirubin (TBIL) is 35.8 mu mol/L, and the liver is alcoholic fatty liver. The liver-benefiting powder is administered with the same dosage as in example 1. After 1 month of administration, the disease condition was relieved. After the medicine is continuously taken for 2 months, the blood biochemical level shows that all indexes are normal, the alanine Aminotransferase (ALT) is 38U/L, the Total Bilirubin (TBIL) is 16.8 mu mol/L, and the color Doppler ultrasound indicates that the liver parenchyma echo is uniform, the fatty liver image disappears, the disease condition is stable, and no relapse occurs.

25. Yunan university patient is higher than a certain one, male, 30 years old. Patients have alcohol addiction, are fond of eating greasy and fat foods at ordinary times, and have fat bodies. In 2 months of 2001, the patients suffered from fatigue, weakness, abdominal distention, pain in liver region, pale tongue, wiry and smooth pulse, pale complexion, swollen liver, abdominal distention, etc. After one month, the symptoms worsen. Introduced by friends, the patients come to a regional hospital for treatment and examination: triglyceride (TG)3.9 mmol/L; 71U/L of liver function glutamic-pyruvic transaminase (ALT) and 42 mu mol/L of Total Bilirubin (TBIL); b ultrasonic prompting: the liver is enlarged. And (3) diagnosis: alcoholic fatty liver. The liver-benefiting powder with 1 treatment course is taken home, and the usage and the dosage are the same as in example 1. After 1 month, the pain of the liver area disappears, no abdominal pain exists, the discomfort symptom is obviously relieved, the liver function is recovered to be normal after the reexamination, and the triglyceride is reduced to be normal and is completely cured.

26. Yunan Shipingxian county patient yellow certain, male, 42 years old. In 11 months in 2000, symptoms such as yellow body, pain in right hypochondrium, discomfort in gastric cavity, bitter taste in mouth, yellow urine, asthenia, poor spirit, and poor sleep can be seen. Visit to a regional hospital in month 2 2001, and physical examination: the skin mucosa of the whole body is slightly yellow-stained, ecchymosis, petechia and skin rash are not seen, superficial lymph nodes of the whole body are not touched and swollen, sclera is yellow-stained, the liver and spleen are not touched under the rib, the liver area has percussion pain, the double kidney areas have no percussion pain, the moving voiced sound and the liquid wave tremor are negative, and the auscultation bowel sound is normal. Glutamic-pyruvic transaminase (ALT) was 697U/L and direct bilirubin (TBIL) was 37.4. mu. mol/L. Acute icterohepatitis is diagnosed. The liver-benefiting powder is administered with the same dosage as in example 1. After 7 days of administration, subjective symptoms gradually improved. After the medicine is continuously taken for 20 days, jaundice and other symptoms are removed, spirit, appetite and sleep are obviously improved, pain in the right hypochondrium is obviously relieved, and liver function is normal.

27. Yunan Shi Tu patient aged 68 years old, Yun nan Shi Tu. The patient was found to have three positive signs of hepatitis B on a physical examination at 1 month in 1999. The patients have not been well treated by taking a lot of liver-protecting medicines, and obvious symptoms such as liver pain, nausea, vomiting and the like appear. In 7 months in 2001, the symptoms of dark face, edema of lower limbs, poor spirit, abdominal distension, diarrhea, unstable walking and the like appear. Then the patient comes to a regional hospital for treatment, and the liver function is as follows: glutamic-pyruvic transaminase (ALT)179U/L, glutamic-oxalacetic transaminase (AST)88U/L, Total Bilirubin (TBIL)38 μmol/L, Direct Bilirubin (DBIL)23 μmol/L; b, hepatitis B virus DNA detection: 1.2X 10⁶B, ultrasonic wave: the liver has normal size and shape, uneven surface, rough internal echo, enlarged spleen volume, thickness of about 52mm and uniform internal echo. And (3) diagnosis: ascites due to cirrhosis of the three major positive of hepatitis B. The disease condition is relieved after one week of treatment by using the liver-tonifying powder, and the liver-tonifying powder with 1 month is taken home, and the usage and the dosage are the same as in example 1. After 1 month, ascites symptoms are obviously improved, the hepatitis B virus number is obviously reduced to less than 10³Liver function is essentially normal.

28. The Yunan Jinping patient is a certain woman in 43 years old. Chronic icterohepatitis, anorexia, aversion to oil, debilitation, epigastric discomfort, liver vague pain, nausea, emesis, aversion to cold, fever, and then dark urine color, and jaundice appears on sclera and skin. In 2001, 7 months, the patient goes to the clinic of the regional hospital and is allowed to take the liver-tonifying powder with the same usage and dosage as in example 1. After 1 month of administration, the subjective symptoms improved and the physical condition was good. After the medicine is taken for 2 months, jaundice and other symptoms are resolved, the spirit and appetite are obviously improved, the liver and spleen retract, and various indexes of the liver function are normal.

29. Yunan province Hekou county king certain woman, 51 years old. The patient often has a small amount of bleeding of gum, and the big three positive of hepatitis B are detected during the later physical examination. In 2001, in 8 months, patients feel hypodynamia, especially after fatigue, and only in 1 month, the patients have no incentive to have abdominal distension and pain, later feel abdominal distension is gradually aggravated, edema of both lower limbs occurs, the times of defecating are increased, and the local hospital has diagnosis results of cirrhosis and ascites. Then go to a regional hospital for treatment. The body is very bad at the time of arrival, five items of hepatitis B are examined: HBsAg (+) HBeAg (+) HBcAb (+). Liver function: alanine Aminotransferase (ALT) is 160U/L, aspartate Aminotransferase (AST) is 188U/L. Color Doppler ultrasound: portal vein 1.3 cm; spleen thickness 6.3cm spleen vein 1.3 cm; the liquid in the abdominal cavity is 13.3 cm. The liver-benefiting powder is administered with the same dosage as in example 1. After 1 month of administration, the subjective symptoms are improved and the physical condition is good. After taking the medicine for 3 months, the patient can be retested, the liver function is recovered, the ascites disappears, and all indexes of the patient are recovered, so that the mental appearance is good.

30. The patient in Zhaotong city of Yunnan province is a female in 42 years old. Abdominal distension, diarrhea, yellow water sample excretion for 7-8 times per day, anorexia, yellow body and eyes, edema of lower limbs, no abdominal pain and fever appear in 7 months in 2001. The doctor visits the hospital in the subarea 9 months in 2001, and examines 79U/L glutamic-pyruvic transaminase (ALT), 48U/L glutamic-oxaloacetic transaminase (AST), 25.1g/L Albumin (ALB), 61 mu mol/L Total Bilirubin (TBIL) and 39.1 mu mol/L Direct Bilirubin (DBIL); the upper abdomen CT shows middle-equivalent ascites, and the diagnosis is alcoholic hepatitis. The liver-benefiting powder is administered with the same dosage as in example 1. After 1 month of administration, abdominal distention is relieved, stomach is improved, and symptoms such as yellow body and eyes, diarrhea and edema of lower limbs are relieved. After the medicine is continuously taken for 1 month, the blood biochemical indicator shows that all indexes are normal and the disease condition is stable.

31. Wana, wang, a pure, 59 year old, Yunnan province. The patients have symptoms of acid regurgitation, belching, hiccup, vague pain of upper abdomen and distention of upper abdomen at the beginning of 1998 month 2, and the treatment of gastropathy takes tens of thousands of yuan after years because the real cause can not be found, but the treatment effect is not always seen. In the end of 2001, examinations were carried out in Kunming's hospital, and early-stage cirrhosis caused liver ascites. The liver disease can be treated by hearing the liver benefiting powder in the subarea hospital immediately, and then the subarea hospital is in a visit. The liver-benefiting powder is administered with the same dosage as in example 1. After taking the medicine for half a month, the subjective symptoms are changed. After another 1 month, the re-diagnosis can be made, the ascites is reduced, and the liver function indexes are recovered to normal.

32. One patient in the city of Yunnan province, male, 60 years old. Can be used for treating liver cirrhosis. In 2001, abdominal pain appears in 7 months, and the part under xiphoid process shows persistent distending pain discomfort, abdominal distension discomfort, vomiting, fever, black stool, edema of lower limbs and other symptoms. In 2001, 8 months, visit the clinic of the regional hospital, prompt the abdomen B-ultrasonic: cirrhosis, splenomegaly, ascites. Upper abdomen CT prompt: liver cirrhosis, splenomegaly, ascites, and focus of the left side of the liver. Three pairs of hepatitis B examinations suggest: HBsAg +, HBcAb +. The liver-benefiting powder is administered with the same dosage as in example 1. After taking the medicine for half a month, the subjective symptoms gradually improve and the physical condition is improved. After the medicine is taken for 2 months again, the mental state is obviously improved, the liver function is recovered to be normal, the pain of the liver area disappears, the edema is relieved, and the vital signs are stable.

33. The patient in Yunnan Maitreya is a female in a certain age of 44 years. Chronic icterohepatitis, anorexia, aversion to oil, debilitation, epigastric discomfort, liver vague pain, nausea, emesis, aversion to cold, fever, and then dark urine color, and jaundice appears on sclera and skin. In 2002, in 3 months, the patients go to a regional hospital to see a doctor and take the liver-tonifying powder, and the usage and the dosage are the same as in example 1. After taking the medicine for half a month, the subjective symptoms are changed to a good degree, and the physical condition is good. After the medicine is taken for 3 months, jaundice and other symptoms are resolved, the spirit and appetite are obviously improved, the liver and spleen are gradually retracted, and all indexes of the liver function are normal.

34. The patient in Yunnan Kaiyuan city is a certain one, male, 57 years old. The patients are detected to be hepatitis B virus carriers in young physical examination, no obvious inducement appears in 3 months in 2002, and the symptoms of weakness, anorexia, paroxysmal vague pain in the middle abdomen, slight reduction of pressing and the like appear. In 2002, 8 months, the doctor visits the outpatient service of a regional hospital. The blood-searching biochemical glutamic-pyruvic transaminase (ALT) is 170U/L, the glutamic-oxalacetic transaminase (AST) is 130U/L, the Total Bilirubin (TBIL) is 26.57U/L, and the Direct Bilirubin (DBIL) is 7.64U/L; the B ultrasonic wave indicates the degree III of fatty liver. Non-alcoholic steatohepatitis was diagnosed. The liver-benefiting powder is administered with the same dosage as in example 1. After taking the medicine for 20 days, the state of illness is relieved, and discomfort symptoms are relieved. After the medicine is continuously taken for 2 months, the blood biochemical indicator shows that all indexes are normal and the physical condition is good.

35. Shannan province, qujing city, wang chi, mai, 57 years old. The patients begin to have symptoms of acid regurgitation, belching, hiccup, vague pain of upper abdomen and distention of upper abdomen at 3 months in 1999, and the treatment cost is tens of thousands of yuan but the treatment effect is not always seen in the coming years because the real causes can not be found. In the end of 2002, examination was performed in Kunming's hospital, and early-stage cirrhosis caused liver ascites. The liver disease can be treated by hearing the liver benefiting powder in the subarea hospital immediately, and then the subarea hospital is in a visit. The liver-benefiting powder is administered with the same dosage as in example 1. After 1 month of administration, the subjective symptoms changed. After taking the medicine for 3 months, the re-diagnosis is carried out, the ascites is reduced, various indexes of the liver function are recovered to be normal, and the physical condition is improved.

36. Some of Yunnan Kunming City patients Guo, male, 48 years old. After drinking in a certain day of 2002 and 8 months, people feel oppression in the chest, discomfort in the liver area, diarrhea, yellow watery stool, dizziness, hypodynamia, cold sweat and limb dampness and cold after drinking. Visit to a regional hospital in 2 months in 2003, and examine liver function: alanine Aminotransferase (ALT) and aspartate Aminotransferase (AST) were elevated at 190U/L and 81U/L, respectively, and the diagnosis of alcoholic fatty liver was made by other examinations. The liver-benefiting powder is administered with the same dosage as in example 1. After 1 month of administration, the discomfort symptoms are alleviated, and the state of the disease is relieved. After the medicine is continuously taken for 2 months, the glutamic-pyruvic transaminase and the glutamic-oxalacetic transaminase are respectively 33U/L and 42U/L, and the disease condition is obviously improved.

There are more than 1000 cases similar to the above cases, which are limited to space relationships and are not described one by one. Through more than 200 cases of clinical practical application, the proportion of the medicines in the range has the same or similar curative effect.

The following are cases with tablets:

37. the screen side county in Yunnan province is a certain woman, and the age is 31 years. In 2003, chronic persistent hepatitis is diagnosed in a certain hospital in Kunming city in Yunnan province, the cost of the medicine is tens of thousands yuan, and the disease course is not cured more than half a year. The introduction of colleagues later shows that the liver-benefiting powder in the subarea hospital can treat the disease. Therefore, the clinic symptoms are general fatigue, weakness, bitter taste, dry throat, liver pain, poor appetite, abdominal distension and the like, the liver is slightly swollen by physical examination, and glutamic-pyruvic transaminase (ALT) is repeatedly or continuously increased by laboratory examination. The liver-benefiting powder tablet I is taken by the following dosage: the preparation is administered in 6 tablets each time, three times a day, and with boiled water. After taking the medicine for 3 months, the subjective symptoms are changed to a good degree, and the physical condition is good. After 3 months of re-taking, the liver gradually retracts, the pain symptom of the liver area is relieved, the spirit and the appetite are obviously improved, and all indexes of the liver function are normal.

38. The patient in Yunan old city is somehow cudged, male, and 36 years old. The patients were found to have three positive signs of hepatitis B in 2 months of physical examination in 2001, and the liver function index were tested to be normal. In 12 months in 2003, the patients feel inappetence, fatigue, aversion to greasy food and nausea. When the patient goes to a regional hospital for diagnosis, the blood is examined to show 505U/L glutamic-pyruvic transaminase (ALT), 167U/L glutamic-oxaloacetic transaminase (AST) and other liver function indexes are normal, and the patient is diagnosed as transaminase increase. The dosage of Yigansan I tablet for oral administration is the same as that in example 37. After taking the medicine for half a month, the blood circulation shows that all indexes of liver function are normal, glutamic-pyruvic transaminase and glutamic-oxalacetic transaminase reach normal values, hepatitis B virus can be effectively inhibited, and the state of an illness is stable.

39. The patient in Yunnan Luchun county is a certain plum, male and 42 years old. Symptoms such as yellow body, pain in right hypochondrium, discomfort in gastric cavity, bitter taste in mouth, yellow urine, weakness of whole body, poor spirit, poor sleep and the like appear in 9 months in 2003. Visit to regional hospital in 2004 within 1 month, examine: the skin mucosa of the whole body is slightly yellow-stained, ecchymosis, petechia and skin rash are not seen, superficial lymph nodes of the whole body are not touched and swollen, sclera is yellow-stained, the liver and spleen are not touched under the rib, the liver area has percussion pain, the double kidney areas have no percussion pain, the moving voiced sound and the liquid wave tremor are negative, and the auscultation bowel sound is normal. Glutamate pyruvate transaminase (ALT) was 267U/L, direct bilirubin (TBIL) 25.4. mu. mol/L. Acute icterohepatitis (viral hepatitis) is diagnosed. The dosage of Yigansan I tablet for oral administration is the same as that in example 37. After 7 days of administration, subjective symptoms gradually improved. After the medicine is continuously taken for half a month, jaundice and other symptoms are removed, spirit, appetite and sleep are obviously improved, pain in the right hypochondrium disappears, liver function is normal, and physical conditions are good.

40. A yunnan jig-saw patient is somebody, a woman, and 37 years old. The patients with hepatitis B virus are subjected to physical examination 10 years ago. After 9 months in 2003, patients often have symptoms of inappetence, nausea, oil aversion, easy fatigue, persistent distending pain in the right upper abdomen, and the like. The early stage of hepatitis B is diagnosed from 1 month to the regional hospital in 2004. The dosage of Yigansan I tablet for oral administration is the same as that in example 37. After 1 month of administration, the disease condition is obviously relieved, and the discomfort symptom is relieved. After the medicine is continuously taken for 2 months, the state of the disease is obviously improved and the mental state is good.

41. The Yunan Jinping county patient is Gong Heng, male, 39 years old. Chronic icteric hepatitis with symptoms of inappetence, nausea, vomiting, aversion to oil, liver pain, asthenia, fever, jaundice, etc. In 2004, 7 months, the physician visits the regional hospital to take the liver-tonifying powder, and the dosage is the same as example 1. After taking the medicine for 2 months, the subjective symptoms are gradually improved, and the physical condition is good. Blood tests show that glutamic-pyruvic transaminase (ALT) and direct bilirubin (TBIL) are reduced obviously. Before taking the liver benefiting powder, the glutamic-pyruvic transaminase (ALT) is 385U/L, and the direct bilirubin (TBIL) is 67 mu mol/L; after taking the liver-benefiting powder for half a month, the glutamic-pyruvic transaminase (ALT) is 95U/L, and the direct bilirubin (TBIL) is 26 mu mol/L. After the liver benefiting powder is taken for 1 month, the liver function is recovered to be normal, the pain of the liver area disappears, and the vital signs are stable.

42. One of plum, Mongolian, Yunnan province, male, 41 years old. The patients can check the hepatitis B at a young age, the hepatitis B develops into cirrhosis in 2004 and gradually worsens, and then the patients are introduced by friends to know that the liver-tonifying powder in the regional hospitals can treat the hepatitis B. Then the doctor visits the doctor before. At that time, the patients have poor health, large amount of ascites, poor nutrition status of the whole body, and the hepatitis B virus amount is checked to be 10⁸Above, liver function is seriously impaired. The dosage of the liver-benefiting powder tablet II is the same as that in example 37. After 1 month of administration, the subjective symptoms improved. After being taken for 2 months, the ascites disappears, the hepatitis B virus quantity is obviously reduced to less than 10³The liver function is normal, and the spirit and appetite are obviously improved.

43. Some tiger of Yunnan Luxi county patients, male, 39 years old. The patients are detected as hepatitis B virus carriers in physical examination at young age, and the patients are stable in illness state and do not need treatment because all the bodies are good at that time. Due to the working requirement, the patient often drinks too much, overtime is tired, and much nursing is not paid attention. After 11 months in 2004, the symptoms of hypodynamia, insomnia, discomfort and pain in the liver area, inappetence and the like always appear. Listen to friend and say that the regional hospital has good treatment for hepatitis B, and visit the doctor 6 months ago in 2005. Five items of hepatitis B were examined: HBsAg positive, HBeAg positive, anti-HBc positive; liver function: glutamic-pyruvic transaminase (ALT)102U/L, Total Bilirubin (TBIL)39 μmmol/L; hepatitis B virus DNA positive; and B ultrasonic liver echo enhancement. Diagnosing chronic hepatitis B active stage. The dosage of Yigansan I tablet for oral administration is the same as that in example 37. After taking for 1 month, the disease condition is obviously relieved, and the discomfort symptom is relieved. After taking the medicine for 2 months, the liver function is recovered to normal, the blood level shows that all indexes are normal, and the body is recovered well.

44. One patient, woman, in Mongyi City of Yunnan province, aged 55 years. The patients were examined at the young age and were carriers of hepatitis B virus. Nausea and hematemesis appear after eating in 12 months in 2003, dark red blood clots and stomach contents exist, the cypress oil is discharged, and the patients have dark stool and are accompanied with palpitation, hypodynamia, dizziness, headache, abdominal pain, dyspnea and short breath. The clinic visit of the regional hospital in 2 months in 2004 shows that the blood and the body are showing that calcium (Ca) is reduced, Total Bilirubin (TBIL), Direct Bilirubin (DBIL), glutamic-pyruvic transaminase (ALT) and glutamic-oxaloacetic transaminase (AST) are increased, and the liver cirrhosis is diagnosed. The dosage of the liver-benefiting powder tablet II is the same as that in example 37. After the medicine is taken for 1 month, the subjective symptoms are changed. After the liver-benefiting powder is continuously taken for 2 months, the diagnosis is repeated, the liver function is recovered to be normal, the blood biochemical indicator shows that all indexes are normal, and the physical condition is good.

45. The patient who wenwei in Yunnan province, longyi, is 39 years old. Symptoms such as fever, malaise, hypodynamia, anorexia, nausea, emesis, right upper abdomen discomfort, jaundice and the like appear in 6 months in 2005. The patients are diagnosed in a hospital in different areas in 11 months in 2005, and the body is found to be yellow in skin and sclera, yellow in urine, high in direct bilirubin concentration, positive in bilirubin and urobilinogen, soft in texture, tender in touch pain and percussion pain, swollen in liver and spleen, and diagnosed as acute icteric hepatitis. The liver-benefiting powder I tablet is taken by the hospital after going home, and the dosage is the same as that in example 37. After half a month, jaundice and other symptoms subside, appetite is improved obviously, liver and spleen retract, liver function returns to normal, and physical condition is good.

46. Yunnan Puer ear patients, Sunzhi, Man, 53 years old. Patients had poor spirit, emaciation, enlarged abdomen, swollen lower limbs and scanty urine for 2 years. The patient comes to a regional hospital for a diagnosis in 10 months in 2005, and the tongue of the patient is red, the tongue coating is yellow and greasy, and the pulse is wiry and rapid. Physical examination: dark and gloomy complexion, slight yellow staining of sclera, no abnormalities of heart and lung, abdominal distension, varicose veins of abdominal wall, edema of both lower limbs. Five hepatitis B HBsAg (ten), HBeAb (ten) and HBcAb (ten), and the DNA detection result is positive; liver function glutamic-pyruvic transaminase (ALT)199U/T, glutamic-oxalacetic transaminase (AST)125U/L, Total Bilirubin (TBIL)37.8 μmol/L, Albumin (ALB)42 g/L; type B ultrasonography shows liver cirrhosis, splenomegaly and massive ascites. And (3) diagnosis: viral hepatitis (type b) cirrhosis (decompensated) ascites. The dosage of the liver-benefiting powder tablet II is the same as that in example 37. After 1 month of administration, the symptoms such as improved spirit, increased appetite, debilitation, abdominal distention, edema of both lower limbs, etc. are relieved. After the medicine is taken home for 3 months, the examination is repeated, the albumin is improved, the ascites is resolved, the liver function is obviously improved, the alanine Aminotransferase (ALT)51U/T, the aspartate Aminotransferase (AST)49U/L, the Total Bilirubin (TBIL)21.8 mu mol/L and the Albumin (ALB)44 g/L.

47. Yunan Hekou county patient model, woman, 64 years old. The patient self-states the history of acute hepatitis, the main clinical symptoms are general fatigue, weakness, bitter taste, dry throat, pain in two ribs, abdominal distension, insomnia, dreaminess, poor appetite and the like, the liver is slightly swollen by physical examination, the liver area has tenderness and percussion pain, and the symptoms are aggravated in 12 months in 2003. The patient is diagnosed in a regional hospital within 7 months in 2004, the main clinical symptoms are debilitation, liver pain, inappetence and other symptoms which continuously exist, and the physical signs of emaciation, sallow complexion, hepatosplenomegaly, hard texture and the like appear in the body examination. Glutamate pyruvate transaminase (ALT) was 598U/L, direct bilirubin (TBIL) was 24.4. mu. mol/L. Diagnosing chronic persistent hepatitis. The dosage of Yigan san (liver benefiting powder for first) is the same as that in example 37. After taking for 1 month, subjective symptoms gradually improve, symptoms such as bitter taste in mouth, dry throat, abdominal distension and the like gradually disappear, spirit, appetite and sleep are obviously improved, and pain in liver area is obviously relieved. After the medicine is continuously taken for 3 months, the liver function is normal, the liver and the spleen are reduced compared with the former, the texture is soft, and the physical condition is good.

48. Yunan Lijiang patient and somebody, male, 46 years old. Patients have alcohol addiction, are fond of eating greasy and fat foods at ordinary times, and have fat bodies. In 2007 in 5 months, there appeared fatigue, weakness, abdominal distention, pain in liver area, pale tongue, wiry and smooth pulse, pale yellow complexion, swollen liver, abdominal distention, etc. After one month, the symptoms worsen. Introduced by friends, the patients come to a regional hospital for treatment and examination: triglyceride (TG)3.7 mmol/L; 101U/L of liver function glutamic-pyruvic transaminase (ALT) and 52 mu mol/L of Total Bilirubin (TBIL); b ultrasonic prompting: the liver is enlarged. And (3) diagnosis: alcoholic fatty liver. The Yigansan I tablet with the dosage of 1 month is taken home, the usage amount is the same as that in the case 37, the pain of the liver area disappears after one month, no abdominal pain exists, the discomfort symptom is obviously relieved, the liver function is found to be normal after the patient continues to take the tablet for 1 month, the triglyceride is obviously reduced, and the patient is completely cured.

49. Wu and Nu of Yunan old City patients aged 21 years. No obvious induction of abdominal pain occurs in 3 months of 2007, and the pain is paroxysmal vague pain in the middle and upper abdomen, accompanied by abdominal distension, dizziness, vomiting and limb weakness. When the doctor visits the hospital in different areas in 2007, the physician finds that the liver is large, the transverse finger can touch 4 below the rib, accompanied by the splenomegaly, and the transverse finger can touch 2 below the rib. Fatty liver was diagnosed. The dosage of Yigansan I tablet for oral administration is the same as that in example 37. After 1 month of administration, the disease condition is relieved and the discomfort symptom is relieved. After the patient continues to take the medicine for 1 month, the liver function is restored to normal and the mental state is good.

50. Yunan university patients are somebody white, male, and 54 years old. The history of alcoholism is more than 30 years, and 3 months in 2007, no obvious inducement exists, oil-dropping and hypodynamia appear, and no attention is paid, and diagnosis and treatment are not carried out. Vomiting coffee-like gastric contents after drinking in 2007 in 9 months, accompanied by dizziness, palpitation, pale complexion, profuse sweat and blurred vision. Through the introduction of relatives, the family members are sent to a regional hospital for treatment, the Hospital looks up 156U/L glutamic-pyruvic transaminase (ALT) and 97U/L glutamic-oxalacetic transaminase (AST) are diagnosed as alcoholic liver diseases, and the patient is allowed to take Yigansan No. I tablets, the dosage of which is the same as that in example 37. After 1 month of administration, the disease condition was relieved. After the medicine is continuously taken for 1 month, the alanine Aminotransferase (ALT) is reduced to 37U/L, the aspartate Aminotransferase (AST) is reduced to 41U/L, the disease condition is stable, and the physical condition is good.

51. Sunzhi, male, 41 years old, is a patient in the Yunnan Pink county, lan. Due to the work requirement, the smoking and drinking are often excessively performed, and the fatigue is excessive. After 5 months in 2007, symptoms such as hypodynamia, weakness, fatigue, lassitude, insomnia, dreaminess, epigastric discomfort, abdominal distension and the like always appear. Visit to the outpatient clinic of a regional hospital in 11 months of 2007. Diagnosing acute hepatitis B. The liver-benefiting powder tablet I is taken with the dosage of the same method as that of the 37 and the tea preparation I is taken at the same time. After 1 month of administration, the disease condition is obviously relieved, and the discomfort symptom is relieved. After the medicine is continuously taken for 2 months, the hepatitis B virus turns negative and the physical condition is good.

52. Yunan Shipingzhen patient, Longzhi, male, is 50 years old. The patient was found to have hepatitis B with four positive signs at 1 month of physical examination in 2000. The patients have not good condition after taking a lot of liver-protecting medicines, and obvious symptoms such as liver pain, nausea, vomiting, liver palms, spider nevus and the like appear. In 7 months in 2001, the symptoms of dark face, edema of lower limbs, poor spirit, abdominal distension, diarrhea, unstable walking and the like appear. Then the patient comes to a regional hospital for treatment, and the liver function is as follows: glutamic-pyruvic transaminase (ALT)479U/L, glutamic-oxalacetic transaminase (AST)288U/L, Total Bilirubin (TBIL)38 μmol/L, Direct Bilirubin (DBIL)23 μmol/L; b, hepatitis B virus DNA detection: 1.2X 10⁶(ii) a B, ultrasonic wave: the liver is abnormal in size and shape, uneven in surface, fibrosis, rough in internal echo, enlarged in spleen volume, about 52mm in thickness and uneven in internal echo. And (3) diagnosis: liver cirrhosis due to the four major positive of hepatitis B. The liver-benefiting powder tablet II and the tea preparation I are taken simultaneously. The usage amounts are the same as in example 37 and example 1, respectively. The disease condition is relieved after one month, and the continuous medication is rechecked after half a year, so that the four positive of the hepatitis B is changed into negative, and the liver function is normal.

Claims

1. The traditional Chinese medicine composition for treating the liver diseases is characterized by comprising the following raw materials in parts by weight: 1 part of swertia mileensis, 0.4-0.7 part of oriental wormwood, 0.4-0.7 part of astragalus root, 0.3-0.6 part of verbena, 0.2-0.5 part of dyers woad leaf, 0.1-0.2 part of bupleurum root, 0.1-0.2 part of ganoderma lucidum, 0.02-0.08 part of scutellaria root and 0.01-0.04 part of gentian.

2. The traditional Chinese medicine composition according to claim 1, wherein the traditional Chinese medicine composition comprises the following raw material components in parts by weight: 1 part of swertia mileensis, 0.53 part of oriental wormwood, 0.53 part of astragalus root, 0.5 part of verbena, 0.37 part of dyers woad leaf, 0.17 part of bupleurum root, 0.13 part of ganoderma lucidum, 0.067 part of scutellaria baicalensis and 0.033 part of gentian.

3. The traditional Chinese medicine composition for treating the liver diseases is characterized by comprising the following raw materials in parts by weight: 1 part of swertia mileensis, 0.4-0.7 part of oriental wormwood, 0.4-0.7 part of astragalus root, 0.3-0.6 part of verbena, 0.2-0.5 part of dyers woad leaf, 0.1-0.2 part of radix bupleuri, 0.1-0.2 part of lucid ganoderma, 0.02-0.08 part of scutellaria baicalensis, 0.01-0.04 part of felwort, 0.1-0.2 part of pseudo-ginseng and 0.1-0.2 part of oldenlandia diffusa;

or the following steps: 1 part of swertia mileensis, 0.4-0.7 part of oriental wormwood, 0.4-0.7 part of astragalus root, 0.3-0.6 part of verbena, 0.2-0.5 part of dyers woad leaf, 0.1-0.2 part of bupleurum root, 0.1-0.2 part of lucid ganoderma, 0.02-0.08 part of scutellaria root, 0.01-0.04 part of gentian and 0.1-0.2 part of pseudo-ginseng;

or the following steps: 1 part of swertia mileensis, 0.4-0.7 part of oriental wormwood, 0.4-0.7 part of astragalus root, 0.3-0.6 part of verbena, 0.2-0.5 part of dyers woad leaf, 0.1-0.2 part of radix bupleuri, 0.1-0.2 part of lucid ganoderma, 0.02-0.08 part of scutellaria baicalensis, 0.01-0.04 part of felwort and 0.1-0.2 part of oldenlandia diffusa.

4. The traditional Chinese medicine composition according to any one of claims 1 to 3, wherein the fineness of the composition is greater than 60 mesh.

5. The composition of any one of claims 1-3, wherein the composition is in the form of a tea, capsule or tablet.

6. Use of a Chinese medicinal composition according to any one of claims 1 to 5 for the preparation of a preparation for the treatment of liver diseases.

7. The use of claim 6, wherein the liver disease comprises one or more of acute icterohepatitis, chronic persistent hepatitis, cirrhosis, hepatic ascites, alcoholic hepatitis, fatty liver, and hepatitis B.

8. The use according to claim 7, wherein the Chinese medicinal composition is a Chinese medicinal composition comprising 0.1-0.2 parts of notoginseng radix when the liver disease is severe liver disease accompanied with liver ascites; when the liver disease is serious liver injury, the traditional Chinese medicine composition contains 0.1-0.2 part of oldenlandia diffusa.

9. Use of a Chinese medicinal composition according to any one of claims 1 to 5 in the manufacture of a formulation for reducing the level of one or more of glutamic-pyruvic transaminase, glutamic-oxalacetic transaminase, and direct bilirubin.

10. Use according to any one of claims 6 to 9, wherein the formulation comprises a medicament, tea, capsule or tablet.