CN106109731A - A kind of Chinese medicine composition treating chronic hepatopathy and preparation method thereof - Google Patents

A kind of Chinese medicine composition treating chronic hepatopathy and preparation method thereof Download PDF

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CN106109731A
CN106109731A CN201610583859.9A CN201610583859A CN106109731A CN 106109731 A CN106109731 A CN 106109731A CN 201610583859 A CN201610583859 A CN 201610583859A CN 106109731 A CN106109731 A CN 106109731A
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chinese medicine
medicine composition
raw material
treating chronic
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赵玮
付慧玲
刘海霞
张海容
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/51—Gentianaceae (Gentian family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
    • A61K36/195—Strobilanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315—Isatis, e.g. Dyer's woad
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/85—Verbenaceae (Verbena family)
    • A—HUMAN NECESSITIES
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/855—Clerodendrum, e.g. glorybower
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    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The present invention provides a kind of Chinese medicine composition treating chronic hepatopathy, is made up of the raw material of following parts by weight: Herba Swertiae Mileensis 1 weight portion；Herba Artemisiae Scopariae 0.4 0.7 weight portion；The Radix Astragali 0.4 0.7 weight portion；Herba Verbenae 0.3 0.6 weight portion；Folium Isatidis 0.2 0.5 weight portion；Radix Bupleuri 0.1 0.2 weight portion；The Rhizoma Atractylodis Macrocephalae 28 weight portion；Radix Ginseng Rubra 10 15 weight portion；Rhizoma Corydalis 10 13 weight portion；Radix Stephaniae Tetrandrae 15 25 weight portion；The present invention also provides for the preparation method of a kind of Chinese medicine composition treating chronic hepatopathy, and compared with prior art, the present invention has a following beneficial effect: can strengthening vital QI to eliminate pathogenic factors, clearing away heat-damp and promoting diuresis, clear dampness-heat in the liver and gallbladder, the wet fire of eliminating pathogen in the liver gallbladder.For treating acute icterohepatitis, chronic icterohepatitis, chronic persistent hepatitis, liver cirrhosis, hepatic ascites, alcoholic hepatitis, fatty liver, hepatitis B, transaminase rise high disease, it may also be used for prevent and treat hepatocarcinoma etc..

Description

A kind of Chinese medicine composition treating chronic hepatopathy and preparation method thereof
Technical field
The present invention is a kind of Chinese medicine composition treating chronic hepatopathy and preparation method thereof, is specifically related to one and treats chronic Chinese medicine composition of hepatitis, chronic hepatitis gravis and subacute severe hepatitis and preparation method thereof.
Background technology
Chronic hepatitis, chronic hepatitis gravis and subacute severe hepatitis are owing to hepatitis virus invades after human body, not by Body is removed in time, causes chronic lesion and the severe infringement of liver.Disease sees pale complexion or binocular, complexion xanthochromia, and asthenia is weary Power, feeling of oppression and fullness in the chest and epigastrium, anorexia, splenomegaly, spider angioma, liver palm, liver function is gently abnormal to severe.Severely impact human body to be good for Health, the most then cause the death of people.To social production, learn, live, family brings injury greatly.Particularly B-type hepatitis development The probability becoming chronic hepatitis and subacute severe hepatitis is bigger.In China's population, the people suffering from hepatitis B is a lot of, the most especially Effective Drug therapy.As long as the pathological changes of chronic hepatitis, slow weight liver and subacute heavy liver is effectively treated and is controlled by we System, protects patient's body, it will be greatly potentiated and enhanced the physical constitution of China's population.
Though motherland's medical science is without chronic hepatitis, weigh liver, the title of subacute heavy liver slowly, but its clinical symptoms is equivalent to " yellow Subcutaneous ulcer ", " acute jaundice ", " side of body pain ", the disease scope such as " asthenia ".It is due to retention of damp-heat in the interior, strongly fragrant the most puzzled, injure caused by vitality of human body.
Summary of the invention
For prior art exist deficiency, it is an object of the present invention to provide a kind of Chinese medicine composition treating chronic hepatopathy and Its preparation method, with the problem solving to propose in above-mentioned background technology.
To achieve these goals, the present invention is to realize by the following technical solutions: a kind of treat chronic hepatopathy Chinese medicine composition, is made up of the raw material of following parts by weight:
Further, raw material also includes Ramulus Cinnamomi, Fructus Jujubae and Radix Glycyrrhizae.
Further, containing Ramulus Cinnamomi 25-30 part in the raw material of every 100 weight portions, containing big in the raw material of every 100 weight portions Fructus Jujubae 5-10 part, containing Radix Glycyrrhizae 10-15 part in the raw material of every 100 weight portions.
Further, it is made up of the raw material of following parts by weight:
The preparation method of a kind of Chinese medicine composition treating chronic hepatopathy, takes the medical material of above-mentioned weight portion, adds medical material gross weight The water of 3-5 times of amount, soaks 80-120 minute, at a temperature of ambient temperature is 60-80 °, decocts 5-7 time, and each 1-3 is little Time, filtering, merging filtrate, the extractum of filtrate reduced in volume to relative density 1.25-1.35, this relative density is to take the photograph at 55-58 Testing result under family name's degree, adding ethanol to alcohol content is 58-87%v/v, stands 24-32 hour, takes supernatant, reclaims ethanol To concentrating, obtain pharmaceutical preparation.
Further, described pharmaceutical preparation includes tablet, capsule, pill, powder, granule, syrup, oral liquid.
Beneficial effects of the present invention: a kind of Chinese medicine composition treating chronic hepatopathy of the present invention and preparation method thereof, red Join sweet flat strongly invigorating primordial QI, promote hepatic cell growth, make the hepatic tissue of necrosis be repaired；It is aided with the temperature invigorating the spleen and benefiting QI of the Rhizoma Atractylodis Macrocephalae, promotees Enter the reply of gastrointestinal function；The hardship of the assistant Rhizoma Atractylodis Macrocephalae, the property of the high benefit of Radix Ginseng Rubra processed, two medicines share, and play strongly invigorating primordial QI altogether, hepatoprotective, Recover the effect of liver function.Be applicable to chronic hepatitis, weigh liver slowly, subacute heavy liver causes vitality of human body deficiency syndrome, disease sees pale complexion Or sallow, body, mesh, complexion xanthochromia, fatigue and weakness, anorexia, feeling of oppression and fullness in the chest and epigastrium, rib side of body dull pain, splenomegaly, liver function is gently to severe Abnormal etc., can strengthening vital QI to eliminate pathogenic factors, clearing away heat-damp and promoting diuresis, clear dampness-heat in the liver and gallbladder, the wet fire of eliminating pathogen in the liver gallbladder.For treating acute icterohepatitis, chronic Huang Subcutaneous ulcer hepatitis, chronic persistent hepatitis, liver cirrhosis, hepatic ascites, alcoholic hepatitis, fatty liver, hepatitis B, transaminase rise high disease, also Can be used for preventing and treating hepatocarcinoma etc..
Detailed description of the invention
For the technological means making the present invention realize, creation characteristic, reach purpose and be easy to understand with effect, below in conjunction with Detailed description of the invention, is expanded on further the present invention.
The present invention provides a kind of technical scheme: a kind of Chinese medicine composition treating chronic hepatopathy, by following parts by weight Raw material is made:
Raw material also includes Ramulus Cinnamomi, Fructus Jujubae and Radix Glycyrrhizae.
Containing Ramulus Cinnamomi 25-30 part in the raw material of every 100 weight portions, containing Fructus Jujubae 5-10 part in the raw material of every 100 weight portions, Containing Radix Glycyrrhizae 10-15 part in the raw material of every 100 weight portions.
The preparation method of a kind of Chinese medicine composition treating chronic hepatopathy, takes the medical material of above-mentioned weight portion, adds medical material gross weight The water of 3-5 times of amount, soaks 80-120 minute, at a temperature of ambient temperature is 60-80 °, decocts 5-7 time, and each 1-3 is little Time, filtering, merging filtrate, the extractum of filtrate reduced in volume to relative density 1.25-1.35, this relative density is to take the photograph at 55-58 Testing result under family name's degree, adding ethanol to alcohol content is 58-87%v/v, stands 24-32 hour, takes supernatant, reclaims ethanol To concentrating, obtain pharmaceutical preparation.
Pharmaceutical preparation includes tablet, capsule, pill, powder, granule, syrup, oral liquid.
As one embodiment of the present of invention: be made up of the raw material of following parts by weight:
In the feed, the sweet flat strongly invigorating primordial QI of Radix Ginseng Rubra, promote hepatic cell growth, make the hepatic tissue of necrosis be repaired；It is aided with The temperature invigorating the spleen and benefiting QI of the Rhizoma Atractylodis Macrocephalae, promotes the reply of gastrointestinal function；The hardship of the assistant Rhizoma Atractylodis Macrocephalae, the property of the high benefit of Radix Ginseng Rubra processed, two medicines share, and play altogether Strongly invigorating primordial QI, hepatoprotective, recovers the effect of liver function.Be applicable to chronic hepatitis, weigh liver slowly, subacute heavy liver causes vitality of human body Deficiency syndrome, disease sees pale or sallow complexion, body, mesh, complexion xanthochromia, fatigue and weakness, anorexia, feeling of oppression and fullness in the chest and epigastrium, rib side of body dull pain, spleen Greatly, liver function is gently abnormal etc. to severe, can strengthening vital QI to eliminate pathogenic factors, clearing away heat-damp and promoting diuresis, clear dampness-heat in the liver and gallbladder, the wet fire of eliminating pathogen in the liver gallbladder.For treating urgency Property icterohepatitis, chronic icterohepatitis, chronic persistent hepatitis, liver cirrhosis, hepatic ascites, alcoholic hepatitis, fatty liver, hepatitis B, Transaminase rises high disease, it may also be used for prevent and treat hepatocarcinoma etc..
As an alternative embodiment of the invention: Herba Swertiae Mileensis 1 weight portion；Herba Artemisiae Scopariae 0.4 weight portion；The Radix Astragali 0.7 weight portion；Horse Whip grass 0.6 weight portion；Folium Isatidis 0.5 weight portion；Radix Bupleuri 0.2 weight portion；The Rhizoma Atractylodis Macrocephalae 8 weight portion；Radix Ginseng Rubra 13 weight portion；Rhizoma Corydalis 10 Weight portion；Radix Stephaniae Tetrandrae 15 weight portion；Ramulus Cinnamomi 25 weight portion；Fructus Jujubae 10 weight portion；Radix Glycyrrhizae 10 weight portion, takes the medicine of above-mentioned weight portion Material, adds the water of 3 times of medical material gross weight, soaks 120 minutes, be at a temperature of 70 ° in ambient temperature, decoct 7 times, each 2 little Time, filtering, merging filtrate, the extractum of filtrate reduced in volume to relative density 1.25-1.35, this relative density is at 55 degrees Celsius Under testing result, adding ethanol to alcohol content is 58-87%v/v, stands 32 hours, takes supernatant, reclaims ethanol to concentration, Obtain pharmaceutical preparation.
As an alternative embodiment of the invention: provide a clinical case:
Hefei ,Anhui Dong patient so-and-so, man, 53 years old.Occur in March, 2014 heating, general malaise, weak, loss of appetite, The symptoms such as nausea and vomiting, right epigastric discomfort, jaundice.In April, 2015 comes subregion hospital admission, is diagnosed as liver cirrhosis.Hepatitis B five Item HBsAg (ten), HBeAb (ten), HBcAb (ten), DNA detection result is positive；Liver function glutamate pyruvate transaminase (ALT) 130U/T (normal 0-40), glutamic oxaloacetic transaminase, GOT (AST) 120U/L (normal value 0-40), total bilirubin (TBIL) 32.4umol/L, albumin (ALB)33g/L；B ultrasonic shows liver cirrhosis, splenomegaly, a large amount of ascites.Diagnosis: viral hepatitis (B-mode) liver cirrhosis (losing compensatory) ascites. Allowing it take pharmaceutical preparation of the present invention, one day 30～50g, for tea-drinking use, boiling water soaks 5～10 minutes, or boils 5-10 minute. After taking 3 months, spirit takes a turn for the better, appetite increases, remission.After going home to continue to allow it take pharmaceutical preparation of the present invention 4 months, Patient's abdominal distention disappears, and the mental status is clearly better, quality deliquescing, and ascites disappears, and liver function recovery is normal, and vital sign is steady.
The ultimate principle of the present invention and principal character and advantages of the present invention are more than shown and described, for this area skill For art personnel, it is clear that the invention is not restricted to the details of above-mentioned one exemplary embodiment, and without departing substantially from the present invention spirit or In the case of basic feature, it is possible to realize the present invention in other specific forms.Therefore, no matter from the point of view of which point, all should be by Embodiment regards exemplary as, and is nonrestrictive, the scope of the present invention by claims rather than on state Bright restriction, it is intended that include all changes fallen in the implication of equivalency and scope of claim in the present invention In.
Although moreover, it will be appreciated that this specification is been described by according to embodiment, but the most each embodiment only wraps Containing an independent technical scheme, this narrating mode of description is only that for clarity sake those skilled in the art should Description can also be formed those skilled in the art through appropriately combined as an entirety, the technical scheme in each embodiment May be appreciated other embodiments.

Claims (6)

1. the Chinese medicine composition treating chronic hepatopathy, it is characterised in that: it is made up of the raw material of following parts by weight:
A kind of Chinese medicine composition treating chronic hepatopathy the most according to claim 1, it is characterised in that: raw material also includes osmanthus Branch, Fructus Jujubae and Radix Glycyrrhizae.
A kind of Chinese medicine composition treating chronic hepatopathy the most according to claim 1 and 2, it is characterised in that: every 100 weight Containing Ramulus Cinnamomi 25-30 part in the raw material of part, containing Fructus Jujubae 5-10 part in the raw material of every 100 weight portions, the raw material of every 100 weight portions In containing Radix Glycyrrhizae 10-15 part.
A kind of Chinese medicine composition treating chronic hepatopathy the most according to claim 1 and 2, it is characterised in that: by following heavy The raw material of amount number is made:
5. a preparation method for the Chinese medicine composition for the treatment of chronic hepatopathy according to claim 1 and 2, its feature exists In: take the medical material of above-mentioned weight portion, add the water of 3-5 times of medical material gross weight, soak 80-120 minute, be 60-in ambient temperature At a temperature of 80 °, decocting 5-7 time, each 1-3 hour, filter, merging filtrate, filtrate reduced in volume is to relative density 1.25- The extractum of 1.35, this relative density is the testing result under 55-58 degree Celsius, and adding ethanol to alcohol content is 58-87%v/ V, stands 24-32 hour, takes supernatant, reclaims ethanol and extremely concentrates, obtains pharmaceutical preparation.
A kind of Chinese medicine composition volume preparation method treating chronic hepatopathy the most according to claim 5, it is characterised in that: institute State pharmaceutical preparation and include tablet, capsule, pill, powder, granule, syrup, oral liquid.
CN201610583859.9A 2016-07-15 2016-07-15 A kind of Chinese medicine composition treating chronic hepatopathy and preparation method thereof Pending CN106109731A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108310164A (en) * 2018-05-16 2018-07-24 刘朝顺 It is a kind of treat and prevent acute and chronic hepatitis Chinese medicine composition and application

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104127826A (en) * 2014-08-12 2014-11-05 崔银方 Traditional Chinese medicine composition for treating chronic alcoholic liver disease
CN104523798A (en) * 2014-12-02 2015-04-22 陈永华 Traditional Chinese medicine composition for treating chronic liver disease and preparation method thereof
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Application publication date: 20161116