CN113212936B - Cell transportation is shifted and is deposited case with low temperature freezing - Google Patents

Cell transportation is shifted and is deposited case with low temperature freezing Download PDF

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Publication number
CN113212936B
CN113212936B CN202110457591.5A CN202110457591A CN113212936B CN 113212936 B CN113212936 B CN 113212936B CN 202110457591 A CN202110457591 A CN 202110457591A CN 113212936 B CN113212936 B CN 113212936B
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storage
box
refrigeration
outer box
embedded
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CN113212936A (en
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曹高博
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Bokang Bioengineering Shandong Co ltd
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Bokang Bioengineering Shandong Co ltd
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02Internal fittings
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0236Mechanical aspects
    • A01N1/0263Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
    • A01N1/0273Transport containers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D55/00Accessories for container closures not otherwise provided for
    • B65D55/02Locking devices; Means for discouraging or indicating unauthorised opening or removal of closure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/02Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage
    • B65D81/05Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/18Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/24Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/38Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents with thermal insulation
    • B65D81/3813Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents with thermal insulation rigid container being in the form of a box, tray or like container
    • B65D81/3823Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents with thermal insulation rigid container being in the form of a box, tray or like container formed of different materials, e.g. laminated or foam filling between walls
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D85/00Containers, packaging elements or packages, specially adapted for particular articles or materials
    • B65D85/50Containers, packaging elements or packages, specially adapted for particular articles or materials for living organisms, articles or materials sensitive to changes of environment or atmospheric conditions, e.g. land animals, birds, fish, water plants, non-aquatic plants, flower bulbs, cut flowers or foliage

Abstract

The invention discloses a low-temperature freezing storage box for cell transportation and transfer, which belongs to the technical field of cell freezing storage, wherein refrigerating bodies for refrigerating are embedded at the left side and the right side of a storage box, a refrigerant mixture is filled in the refrigerating bodies, and low temperature generated by mixing reaction is transmitted to buffering water bag layers positioned at the front side and the rear side of an outer box, so that the temperature of an aqueous solution in the buffering water bag layers is suddenly reduced, on one hand, the low-temperature area of the outer box is enlarged, and the storage box for storing cells is in a low-temperature freezing storage environment, on the other hand, under the cooperation of a first heat insulation plate and a second heat insulation plate, the buffering and heat insulation effects of the outer box are effectively improved, the outer box is not easy to shake and the cold air in the outer box is not easy to lose, meanwhile, storage bags are arranged at the left side and the right side of the outer box and are communicated with the refrigerating bodies and are used for long distance road, and the timed supply of the refrigerant is realized, and the refrigerating effect is effectively prolonged.

Description

Cell transportation is shifted and is deposited case with low temperature freezing
Technical Field
The invention relates to the technical field of cell refrigeration and freezing, in particular to a low-temperature freezing box for cell transportation and transfer.
Background
The biotechnology means that people can produce a required product or achieve a certain purpose for human beings by taking modern life science as a basis, combining scientific principles of other basic sciences and adopting advanced scientific and technical means to modify organisms or process biological raw materials according to a preset design. Among them, cell biology is one of modern biotechnology.
In clinical cell research and treatment, independent cell preparation units are needed to provide cells, and cell use units are needed to provide cells, so that the cells achieve the optimal activity in both development and clinical application, and a cell storage and transportation process meeting the standard specification is needed.
Based on the industrial particularity of storage and transportation of stem cells, low-temperature refrigeration treatment needs to be carried out on the stem cells, most of the existing stem cell refrigeration transportation boxes are refrigerated through compressors, and the compressors occupy large space and are not easy to carry out low-temperature transportation on small-specification storage boxes; and current stem cell refrigeration transport box is in the transportation, leads to inside culture dish or test tube etc. to break easily when the vehicle rocks.
Therefore, a low-temperature freezing storage box for cell transportation and transfer is provided to effectively solve the problems in the prior art.
Disclosure of Invention
1. Technical problem to be solved
Aiming at the problems in the prior art, the invention aims to provide a low-temperature freezing storage box for cell transportation and transfer, wherein refrigerating bodies for refrigeration are embedded at the left side and the right side of a storage box, a refrigerant mixture is filled in the refrigerating bodies, and low temperature generated by mixing reaction is conducted to buffering water bag layers positioned at the front side and the rear side of an outer box, so that the temperature of an aqueous solution in the buffering water bag layers is suddenly reduced, on one hand, the low-temperature area of the outer box is enlarged, so that the storage box for storing cells is in a low-temperature freezing storage environment, on the other hand, under the cooperation of a first heat insulation plate and a second heat insulation plate, the buffering and heat insulation effects of the outer box are effectively improved, the outer box is not easy to shake and the cold air in the outer box is not easy to lose, meanwhile, storage bags are arranged at the left side and the right side of the outer box and are communicated with the refrigerating body and are used for long distance road, and the timed supply of the refrigerant is realized, so that the refrigeration effect is effectively prolonged.
2. Technical scheme
In order to solve the above problems, the present invention adopts the following technical solutions.
The utility model provides a cell transportation shifts with low temperature cryopreserved case, includes outer box, the cryopreserved chamber has been seted up to the inside of outer box, cryopreserved intracavity portion inlays to establish and installs and stores the box, it is equipped with a plurality of evenly distributed's first storage chamber to store in the box, the top magnetism of outer box is inhaled to be connected with and is detained the sealed apron of locating on storing the box, sealed apron's bottom is equipped with a plurality of sealed bag stopper that correspond with first storage chamber position, it establishes the chamber all to have seted up on the left and right sides wall of outer box to inlay to establish the intracavity portion and all inlay and be equipped with the refrigeration body, a pair of second storage chamber has all been seted up on the left and right sides top both sides of outer box, and is a plurality of the storage bag that the chamber is linked together and sets up is all inlayed to be equipped with and inlays to establish on the wall of the left and right sides of outer box, and all set up on the both ends lateral wall of outer box with a pair of inlaying and establish the chamber and be linked together the biography chamber and lead the chamber and set up, and be a pair of the conduction intracavity portion all inlay and be equipped with bath water heated board, the outer bag layer, the outer end of bag layer is equipped with the bath heated board, the water heated board that washes by water solution of slow bag is filled to the inside of slow bag.
Furthermore, all fixedly connected with attaches magnetism and inlays and establish the piece on the both ends wall about the storage box, it establishes the piece and is equipped with the catching groove to attach magnetism, set up the gomphosis groove that corresponds with attaching magnetism and inlaying and establishing the piece position on the top lateral wall in chamber to freeze, it has magnetic substance to attach magnetism and inlay the inside packing that establishes the piece, gomphosis inslot bottom is equipped with the magnetism and inhales the layer, utilizes magnetism to inhale the setting, changes in that the storage box can stably put in freezing and deposits the intracavity, and also the technical staff of being convenient for gets the storage box and puts.
Further, all the cladding has the flexible heat conduction cellucotton of one deck on the outer end wall of storage box and on the interior end wall of a plurality of first storage chamber, plays the buffer protection effect promptly, easily will be transferred to storage box department by the produced low temperature of refrigerating body again, realizes the low temperature of storage box and freezes to deposit.
Further, the refrigeration body is including inlaying the refrigeration case of establishing the intracavity of locating, the outer end of refrigeration case is connected with the first thermal insulation board that links up with outer external end wall of outer container mutually, the inside of refrigeration case is equipped with the refrigeration chamber, the top both sides of refrigeration case all are connected with the honeycomb duct that corresponds with a pair of storage bag position, and are a pair of the equal slope downwardly extending of honeycomb duct is inside to the refrigeration case.
Furthermore, the interior bottom in second storage chamber is for with storage bag assorted ellipse shape structure, the bottom of storage bag is equipped with and extends to the inlet pipe of inlaying the chamber top of establishing, be equipped with the metering valve in the inlet pipe, it is a pair of the honeycomb duct sets up with a pair of inlet pipe one-to-one respectively.
Further, the symmetry set up in it establishes the refrigerant in a pair of storage bag of piece left and right sides for ammonium chloride and eight water barium hydroxide respectively to attach the magnetism inlay, the interior top cladding of refrigeration case has the activated carbon adsorption layer, under initial condition, the inside packing of refrigeration case has ammonium chloride and eight water barium hydroxide mixtures, both reaction endotherms refrigeration to create low temperature environment, after the refrigerant mixture in the refrigeration case slowly consumes, utilize a pair of storage bag to carry out the timing ration supply of refrigerant to the refrigeration incasement, thereby effectively prolong refrigeration effect, both produced gases of reaction then are adsorbed by the activated carbon adsorption layer simultaneously.
Further, the top of storage bag is equipped with the shutoff piece, the shutoff piece closely buckles with second storage chamber top wall and establishes the link up, set up the feed inlet that is linked together with storage bag on the shutoff piece, and feed inlet department installs the putty stopper, easily places storage bag stability in the second storage intracavity, also easily technical staff carries out the supply of refrigerant in to storage bag.
Further, a plurality of spring stirring rods of the interior top fixedly connected with of refrigeration case, spring stirring rod is including connecting the spring on refrigeration incasement top, the bottom of spring is equipped with the hammer stem, suspends a plurality of spring stirring rods in midair in the inside of refrigeration case, when this freezing case produces in the transportation and rocks, a plurality of spring stirring rods can be because elasticity and vibration from top to bottom to stir the refrigerant of refrigeration incasement from top to bottom repeatedly, be favorable to accelerating reaction rate.
Further, the inner of buffer water bag layer inlays the refrigeration halfpillar that is equipped with a plurality of evenly distributed, refrigeration halfpillar and buffer water bag in situ are linked together, conduction intracavity end wall has seted up a plurality ofly and refrigeration halfpillar assorted in-connection chamber, both ends extend to respectively to inlaying about the in-connection chamber and establish chamber department, in-connection chamber and inlay and establish chamber looks linking department and inlay the heat conduction fiber stick that is equipped with and offsets the setting with the refrigeration halfpillar, will fill the buffer water bag layer that has aqueous solution and inlay and locate behind the conduction intracavity, aqueous solution and have elastic buffer water bag layer and mutually support, play the cushioning effect on the one hand, on the other hand, the low temperature that produces by refrigeration case department passes through heat conduction fiber stick and conducts to buffer water bag layer department, and buffer water bag layer department temperature reduces fast, and enlarges low temperature area to the even freezing area of storage box has effectively been improved.
Further, first thermal insulation board is including connecting in the first outer buffer layer of refrigeration case outer end, the inside packing of first outer buffer layer has the cotton layer of first heat preservation, the second thermal insulation board is including connecting in the outer buffer layer of second of buffer water bag layer outer end, the inside packing of the outer buffer layer of second has the cotton layer of second heat preservation, both plays the heat preservation effect to the outer terminal surface of outer box, and difficult inside low temperature that realizes scatters and disappears, plays good buffering antidetonation effect again to the storage box of inboard.
3. Advantageous effects
Compared with the prior art, the invention has the advantages that:
(1) This scheme is through inlaying the refrigeration body that is used for the refrigerated in the left and right sides of storage box, the internal portion packing of refrigeration has the refrigerant mixture, the low temperature conduction that the mixed reaction produced is to the buffering water pocket layer department that is located outer box front and back both sides, make the inside aqueous solution temperature shock of buffering water pocket layer, enlarge the low temperature area of outer box on the one hand, thereby make the storage box that the storage has the cell be in a low temperature and freeze the environment of depositing, on the other hand, under the cooperation of first heated board and second heated board, the buffering and the heat preservation effect of this outer box have effectively been improved, be difficult for making rocking of outer box and the loss of its inside air conditioning, and simultaneously, the left and right sides at outer box sets up the storage bag, the storage bag sets up with the internal intercommunication of refrigeration, be used for the long distance on the road, realize the timing supply of refrigerant, thereby effectively prolong refrigeration effect.
(2) All fixedly connected with attaches the magnetism and inlays and establish the piece on the wall of both ends about storage box, attaches the magnetism and inlays and establish the piece and be equipped with the catching groove, set up the gomphosis groove that corresponds with attaching the magnetism and inlay the piece position on the top lateral wall in freezing chamber, attach the magnetism and inlay the inside packing that establishes the piece and have magnetic substance, gomphosis inslot bottom is equipped with magnetism and inhales the layer, utilizes magnetism to inhale the setting, changes in that the storage box can stably put in freezing intracavity, and the technical staff of also being convenient for gets to put storage box.
(3) All the cladding has the flexible heat conduction cellucotton of one deck on the outer end wall of storage box and on a plurality of first storage chamber's the interior end wall, plays the buffer protection effect promptly, easily will be transferred to storage box department by the produced low temperature of refrigerating body again, realizes the low temperature cryopreserving of storage box.
(4) The refrigeration body inlays the refrigeration case of establishing the intracavity including inlaying and locating, the outer end of refrigeration case is connected with the first thermal insulation board that links up with outer external end wall of outer container, the inside of refrigeration case is equipped with the refrigeration chamber, the top both sides of refrigeration case all are connected with the honeycomb duct that corresponds with a pair of storage bag position, a pair of honeycomb duct all inclines downwardly extending to the refrigeration incasement portion, the refrigerant that the symmetry set up in a pair of storage bag of attaching the magnetism and inlaying the piece left and right sides is ammonium chloride and eight water barium hydroxide respectively, the interior top cladding of refrigeration case has the activated carbon adsorption layer, under initial condition, the inside packing of refrigeration case has ammonium chloride and eight water barium hydroxide mixture, both react endothermic refrigeration, in order to create low temperature environment, after the refrigerant mixture of refrigeration incasement slowly consumes, utilize a pair of storage bag to carry out the timing quantitative supply of refrigerant to the refrigeration incasement, thereby effectively prolong refrigeration effect, both produced gas then is adsorbed by the activated carbon adsorption layer simultaneously.
(5) The bottom of the second storage cavity is of an oval structure matched with the storage bag, the bottom of the storage bag is provided with a feeding pipe extending to the top end of the embedded cavity, a metering valve is arranged in the feeding pipe, a pair of guide pipes are arranged in one-to-one correspondence with the pair of feeding pipes respectively, the top of the storage bag is provided with a plugging sheet, the plugging sheet is in close buckling connection with the wall of the top end of the second storage cavity, a feeding port communicated with the storage bag is formed in the plugging sheet, a plugging plug is installed at the feeding port, the storage bag is easy to stably place in the second storage cavity, a technician is also easy to supply refrigerant to the storage bag, and after the refrigerant in the refrigeration box is consumed, the metering valve is controlled to be opened for regularly and quantitatively putting the refrigerant into the refrigeration box.
(6) The inside top fixedly connected with of refrigeration case a plurality of spring stirring stick, spring stirring stick is including connecting in the spring on refrigeration incasement top, and the bottom of spring is equipped with the hammer stem, suspends a plurality of spring stirring sticks in midair in the inside of refrigeration case, when this freezing case produces in the transportation and rocks, a plurality of spring stirring stick can be because elasticity and vibration from top to bottom to stir repeatedly about going on the refrigerant to the refrigeration incasement, be favorable to accelerating reaction rate.
(7) The inner of buffering water pocket layer inlays the refrigeration semicolumn that is equipped with a plurality of evenly distributed, refrigeration semicolumn and buffering water pocket in situ are linked together, conduction intracavity end wall has seted up a plurality ofly and the intercommunication chamber of refrigeration semicolumn assorted, both ends extend to respectively about the intercommunication chamber and inlay and establish chamber department, the intercommunication chamber with inlay and establish chamber department of linking mutually and inlay the heat conduction fiber stick that is equipped with and offsets the setting with the refrigeration semicolumn, the buffering water pocket layer that will pack has aqueous solution inlays and locates behind the conduction intracavity, aqueous solution and the elastic buffering water pocket layer of having mutually supported, play the cushioning effect on the one hand, on the other hand, low temperature that produces by refrigeration case department passes through heat conduction fiber stick and conducts to buffering water pocket layer department, buffering water pocket layer department temperature reduces fast, and enlarge the low temperature area, thereby the even freezing area of storage box has effectively been improved.
(8) First insulation board is including connecting in the first outer buffer layer of refrigeration case outer end, and the inside packing of first outer buffer layer has the cotton layer of first heat preservation, and the second insulation board is including connecting in the outer buffer layer of second of buffering water bag layer outer end, and the inside packing of the outer buffer layer of second has the cotton layer of second heat preservation, has both played the heat preservation effect to the outer terminal surface of outer box, and difficult inside low temperature that realizes scatters and disappears, plays good buffering antidetonation effect again to the storage box of inboard.
Drawings
FIG. 1 is a first exploded view of the present invention;
FIG. 2 is a schematic view of the sealing cover plate of the present invention being separated from the outer case;
FIG. 3 is a partial exploded view of the second aspect of the present invention;
FIG. 4 is a partial exploded view of the third aspect of the present invention;
fig. 5 is a sectional view of the inside of the refrigeration case of the present invention;
fig. 6 is a partial sectional view showing a position where the buffering water bag layer of the present invention is separated from the outer case.
The reference numbers in the figures illustrate:
1 outer box, 101 freezes the deposit chamber, 102 inlays establishes the chamber, 103 second storage chamber, 104 conduction chamber, 105 in-connection chamber, 2 storage boxes, 201 first storage chamber, 3 sealed apron, 301 sealed bag stopper, 4 attach the magnetism and inlay and establish the piece, 5 refrigeration casees, 6 first insulation board, 601 first outer buffer layer, 602 first insulation cotton layer, 7 honeycomb ducts, 8 spring stirring stick, 9 storage bag bags, 10 shutoff pieces, 11 second insulation board, 111 second outer buffer layer, 112 second insulation cotton layer, 12 buffer water bag layers, 13 refrigeration semicolumns, 14 heat conduction fiber stick.
Detailed Description
The drawings in the embodiments of the invention will be combined; the technical scheme in the embodiment of the invention is clearly and completely described; obviously; the described embodiments are only some of the embodiments of the invention; rather than all embodiments, are based on the embodiments of the invention; all other embodiments obtained by a person skilled in the art without making any inventive step; all fall within the scope of protection of the present invention.
In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "top/bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted", "provided", "fitted/connected", "connected", and the like, are to be interpreted broadly, such as "connected", which may be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Example 1:
please refer to fig. 1, a low temperature freezing storage box for cell transportation and transfer, including outer box 1, freezing storage chamber 101 has been seted up to the inside of outer box 1, freezing storage chamber 101 is inside to be set up and to be installed storage box 2, be equipped with a plurality of evenly distributed's first storage chamber 201 in the storage box 2, all fixedly connected with attaches magnetism and inlays establishment piece 4 on the both ends wall of the left and right sides of storage box 2, it is equipped with the catching groove on the establishment piece 4 to attach magnetism, set up the gomphosis groove that corresponds with attaching magnetism and inlaying establishment piece 4 position on the top lateral wall of freezing storage chamber 101, it has magnetic substance to attach magnetism and inlay the inside packing of establishment piece 4, gomphosis inslot bottom is equipped with the magnetism suction layer, utilize magnetism to inhale the setting, it can stably put in freezing storage box 101 to change storage box 2 into storage box 2, and also be convenient for technical staff to get and put storage box 2, all the cladding has the one deck flexible heat conduction fiber cotton on a plurality of first storage chamber 201 on the outer end wall of storage box 2, play the buffer protection effect promptly, easily transmit the low temperature that produces by the refrigeration body to storage box 2 again, realize freezing storage box's low temperature.
Please refer to fig. 1-2, the top magnetic attraction connection of the outer box 1 is connected to the sealing cover plate 3 buckled on the storage box 2, the bottom both sides of the sealing cover plate 3 are also provided with the magnetic attraction layer magnetically connected with the magnetic embedding piece 4, so as to realize the upper and lower magnetic attraction connection, and play a good positioning role, the bottom of the sealing cover plate 3 is provided with a plurality of sealing capsule plugs 301 corresponding to the first storage cavity 201, the sealing capsule plugs 301 have elasticity, the first storage cavity 201 is used for placing test tubes, when the storage box 2 is placed in the freezing storage cavity 101, the sealing cover plate 3 is covered, the sealing capsule plugs 301 at the bottom of the sealing cover plate 3 are just embedded at the top of the first storage cavity 201, so as to effectively limit the top of the test tubes, and play a positioning buffering role, the size structures of the first storage cavity 201 and the sealing capsule plugs 301 can be set according to actual needs.
Referring to fig. 3-5, the left and right side walls of the outer box 1 are both provided with embedding cavities 102, a pair of cavities 102 are embedded with a refrigerating body, the refrigerating body includes a refrigerating box 5 embedded in the embedding cavity 102, the outer end of the refrigerating box 5 is connected with a first heat insulation plate 6 connected with the outer end wall of the outer box 1, the inside of the refrigerating box 5 is provided with a refrigerating cavity, both sides of the top end of the refrigerating box 5 are connected with flow guide pipes 7 corresponding to the positions of the storage bag bags 9, and the flow guide pipes 7 are inclined and extend downwards to the inside of the refrigerating box 5.
A pair of second storage chamber 103 has all been seted up to the left and right sides top of outer box 1, all inlay in a plurality of second storage chambers 103 and be equipped with and inlay the storage bag 9 that establishes chamber 102 and be linked together the setting, and the intussuseption of storage bag 9 is filled with the refrigerant, the interior bottom of second storage chamber 103 be with storage bag 9 assorted oval structure, the bottom of storage bag 9 is equipped with and extends to inlay the inlet pipe of establishing chamber 102 top, be equipped with the metering valve in the inlet pipe, a pair of honeycomb duct 7 sets up with a pair of inlet pipe one-to-one respectively, easily pass through honeycomb duct 7 with the refrigerant in the storage bag 9 leading-in to the refrigeration case 5.
The refrigerants symmetrically arranged in the pair of storage bag bags 9 on the left side and the right side of the magnetic embedding sheet 4 are respectively ammonium chloride and barium hydroxide octahydrate, the inner top of the refrigerating box 5 is coated with an activated carbon adsorption layer, in an initial state, the refrigerating box 5 is filled with a mixture of ammonium chloride and barium hydroxide octahydrate, the ammonium chloride and the barium hydroxide octahydrate react to absorb heat for refrigeration, so as to create a low-temperature environment, the low-temperature environment is transferred to the storage box 2, cells in the storage box 2 are in a frozen state, after the refrigerant mixture in the refrigerating box 5 is slowly consumed, the refrigerant is periodically and quantitatively supplied into the refrigerating box 5 by the pair of storage bag bags 9, so that the refrigeration effect is effectively prolonged, the storage amount of the storage bag 9 can be designed according to actual needs, so as to meet the long-distance refrigeration supply needs, meanwhile, gas generated by the reaction of the ammonium chloride and the barium hydroxide octahydrate can be stably stored in the storage bag 9 when the ammonium chloride and the barium hydroxide octahydrate do not contact reaction.
The top of storage bag 9 is equipped with shutoff piece 10, shutoff piece 10 and second storage chamber 103 top wall are closely buckled and are established linking, set up the feed inlet that is linked together with storage bag 9 on shutoff piece 10, and feed inlet department installs the putty stopper, easily place storage bag 9 stably in second storage chamber 103, also easily technical staff carries out the supply of refrigerant to in the storage bag 9, the inside top fixedly connected with a plurality of spring stirring stick 8 of refrigeration case 5, spring stirring stick 8 is including connecting the spring at the top in refrigeration case 5, the bottom of spring is equipped with the hammer beam, suspend a plurality of spring stirring stick 8 in refrigeration case 5's inside, when this freezing case produces rocking in the transportation, a plurality of spring stirring stick 8 can be because elasticity and independently from top to bottom moderate vibration, thereby play upper and lower repeated stirring effect to the refrigerant in refrigeration case 5, be favorable to quickening reaction rate, improve the refrigeration effect, and it explains that the inner of refrigeration case 5 is equipped with the buffer box that sets up the weak heat conductivity that the inner wall of cavity 102 is laminated, a plurality of spring stirring stick 8 can not influence from top to bottom, can not receive the effective material storage box 2 of the high temperature and can not to dismantle the clean storage box 2 relatively to the high temperature storage box 2 when the refrigeration case 2, can not relatively high temperature storage box 2, can be dismantled to the effective storage box 2, can be avoided.
Referring to fig. 3 and 6, the front and rear side walls of the outer box 1 are provided with a pair of conduction cavities 104 communicated with the pair of embedding cavities 102, a buffer water bag layer 12 is embedded in each of the pair of conduction cavities 104, the outer end of the buffer water bag layer 12 is provided with a second heat-insulating plate 11, the inside of the buffer water bag layer 12 is filled with aqueous solution, one side of the top end of the buffer water bag layer 12 is provided with a liquid inlet, the buffer water bag layer is made of plastic material with certain elasticity, and the lengths of the conduction cavities 104 and the second heat-insulating plate 11 can be set according to actual needs to improve excellent refrigeration and heat-insulating performances.
Specifically, the inner of buffering water bag layer 12 inlays and is equipped with a plurality of evenly distributed's refrigeration semicolumns 13, refrigeration semicolumns 13 and the inside of buffering water bag layer 12 are linked together, the inner endwall of conduction chamber 104 is seted up a plurality of and refrigeration semicolumn 13 assorted in-connection chamber 105, both ends extend respectively to inlay about in-connection chamber 105 and establish chamber 102 department, in-connection chamber 105 with inlay and establish chamber 102 department of linking and inlay and be equipped with the heat conduction fiber stick 14 that offsets with refrigeration semicolumn 13 and set up, the buffering water bag layer 12 that will pack and have aqueous solution inlays and locate behind the conduction chamber 104, aqueous solution and the elastic buffering water bag layer 12 of having mutually supported, play the cushioning effect on the one hand, on the other hand by the produced low temperature of refrigeration case 5 department pass through heat conduction fiber stick 14 and conduct to buffering water bag layer 12 department, the aqueous solution temperature in the buffering water bag layer 12 reduces fast, realize that the low temperature of large tracts of area expands and prolong, thereby effectively improved the even frozen area of storage box 2.
What need supplement here is, first insulation board 6 is including connecting in the first outer buffer layer 601 of 5 outer ends in refrigeration case, the inside packing of first outer buffer layer 601 has first heat preservation cotton layer 602, second insulation board 11 is including connecting in the outer buffer layer 111 of second in buffer water bag layer 12 outer end, the inside packing of the outer buffer layer 111 of second has second heat preservation cotton layer 112, both play the heat preservation effect to the outer terminal surface of outer box 1, difficult inside low temperature of realizing scatters and disappears, play good buffering antidetonation again to inboard storage box 2.
According to the invention, the refrigerating bodies for refrigeration are embedded at the left side and the right side of the storage box 2, the refrigerant mixture is filled in the refrigerating bodies, low temperature generated by mixing reaction is conducted to the buffer water bag layers 12 at the front side and the rear side of the outer box 1, so that the temperature of the aqueous solution in the buffer water bag layers 12 is suddenly reduced, on one hand, the low-temperature area of the outer box 1 is enlarged, and the storage box 2 storing cells is in a low-temperature freezing environment, on the other hand, the buffer performance and the heat insulation performance of the outer box 1 are effectively improved under the matching of the first heat insulation plate 6 and the second heat insulation plate 11, the swinging of the storage box 2 and the loss of cold air in the storage box 2 are not easily caused, meanwhile, the storage bag bags 9 are arranged at the left side and the right side of the outer box 1, and the bag 9 is communicated with the refrigerating bodies and is used for realizing the timed supply of the refrigerant on long roads, thereby effectively prolonging the refrigerating effect.
The components used in the present invention are all standard components or components known to those skilled in the art, and the structure and principle thereof can be known to those skilled in the art through technical manuals or through routine experiments.
The above; but are merely preferred embodiments of the invention; the scope of the invention is not limited thereto; any person skilled in the art is within the technical scope of the present disclosure; the technical scheme and the improved concept of the invention are equally replaced or changed; are intended to be covered by the scope of the present invention.

Claims (6)

1. The utility model provides a cell transportation is frozen with low temperature and is deposited case, includes outer box (1), the inside of outer box (1) has been seted up and has been frozen chamber (101), it installs storage box (2) to freeze chamber (101) inside the setting up, be equipped with a plurality of evenly distributed's first storage chamber (201) in storage box (2), sealed apron (3) that the buckle was located on storage box (2) are inhaled to the top magnetism of outer box (1), its characterized in that: the bottom end of the sealing cover plate (3) is provided with a plurality of sealing bag plugs (301) corresponding to the positions of the first storage cavities (201), the left side wall and the right side wall of the outer box body (1) are respectively provided with an embedded cavity (102), a pair of refrigerating bodies are embedded in the embedded cavities (102), a pair of second storage cavities (103) are respectively arranged on the left top end and the right top end of the outer box body (1), a plurality of storage bag bags (9) communicated with the embedded cavities (102) are respectively embedded in the second storage cavities (103), the storage bags (9) are filled with refrigerating agents, the side walls of the front end and the rear end of the outer box body (1) are respectively provided with a conduction cavity (104) communicated with the embedded cavities (102), a buffer water bag layer (12) is embedded in the conduction cavities (104), the outer end of the buffer water bag layer (12) is provided with a second heat insulation plate (11), and the inner part of the buffer water solution of the buffer bag layer (12) is filled with water;
the refrigerator comprises a refrigeration box (5) which is embedded in an embedded cavity (102), the outer end of the refrigeration box (5) is connected with a first heat preservation plate (6) which is connected with the outer end wall of an outer box body (1), the refrigeration cavity is arranged in the refrigeration box (5), both sides of the top end of the refrigeration box (5) are connected with guide pipes (7) which correspond to a pair of storage bag bags (9), and a pair of guide pipes (7) are inclined and extend downwards into the refrigeration box (5);
the utility model discloses a refrigerator, including refrigeration case (5), the bottom of spring is equipped with the hammer stem, the interior top fixedly connected with of refrigeration case (5) a plurality of spring stirring stick (8), spring stirring stick (8) are including connecting in the spring on refrigeration case (5) interior top.
2. The cryopreservation tank for cell transportation and transfer according to claim 1, wherein: the magnetic material storing box is characterized in that the left end wall and the right end wall of the storing box (2) are fixedly connected with magnetic embedding pieces (4), each magnetic embedding piece (4) is provided with a buckling groove, the top side wall of the freezing cavity (101) is provided with an embedded groove corresponding to the magnetic embedding piece (4), the magnetic embedding piece (4) is filled with magnetic materials, and the bottom of the embedded groove is provided with a magnetic absorption layer.
3. The cryopreservation tank for cell transportation and transfer as defined in claim 2, wherein: the outer end wall of the storage box (2) and the inner end walls of the first storage cavities (201) are coated with a layer of flexible heat-conducting cellucotton.
4. The cryopreservation tank for cell transportation and transfer according to claim 1, wherein: the interior bottom of second storage chamber (103) is for with storage bag (9) assorted ellipse shape structure, the bottom of storage bag (9) is equipped with and extends to the inlet pipe of inlaying and establishing chamber (102) top, be equipped with the metering valve in the inlet pipe, it is a pair of honeycomb duct (7) set up with a pair of inlet pipe one-to-one respectively.
5. The cryopreservation tank for cell transportation and transfer according to claim 2, wherein: the refrigerants symmetrically arranged in the pair of storage bag bags (9) on the left side and the right side of the magnetic embedding sheet (4) are respectively ammonium chloride and barium hydroxide octahydrate, and the inner top of the refrigerating box (5) is coated with an activated carbon adsorption layer.
6. The cryopreservation tank for cell transportation and transfer according to claim 5, wherein: the top of storage bag (9) is equipped with shutoff piece (10), shutoff piece (10) are closely detained with second storage chamber (103) top wall and are established the link up, set up the feed inlet that is linked together with storage bag (9) on shutoff piece (10), and feed inlet department installs the putty stopper.
CN202110457591.5A 2021-04-27 2021-04-27 Cell transportation is shifted and is deposited case with low temperature freezing Active CN113212936B (en)

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