CN114805529B - Freezing storage device for culturing stem cell growth factors - Google Patents
Freezing storage device for culturing stem cell growth factors Download PDFInfo
- Publication number
- CN114805529B CN114805529B CN202111232157.3A CN202111232157A CN114805529B CN 114805529 B CN114805529 B CN 114805529B CN 202111232157 A CN202111232157 A CN 202111232157A CN 114805529 B CN114805529 B CN 114805529B
- Authority
- CN
- China
- Prior art keywords
- test tube
- cryopreservation
- cylinder
- box body
- stem cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000007710 freezing Methods 0.000 title claims abstract description 28
- 230000008014 freezing Effects 0.000 title claims abstract description 28
- 210000000130 stem cell Anatomy 0.000 title claims abstract description 17
- 230000010261 cell growth Effects 0.000 title claims abstract description 15
- 239000003102 growth factor Substances 0.000 title claims abstract description 15
- 238000012258 culturing Methods 0.000 title claims abstract description 9
- 238000003860 storage Methods 0.000 title claims description 7
- 238000005138 cryopreservation Methods 0.000 claims abstract description 31
- 230000007246 mechanism Effects 0.000 claims abstract description 21
- 239000011229 interlayer Substances 0.000 claims abstract description 13
- 238000005192 partition Methods 0.000 claims description 14
- 102100032528 C-type lectin domain family 11 member A Human genes 0.000 claims description 8
- 101710167766 C-type lectin domain family 11 member A Proteins 0.000 claims description 7
- 230000003028 elevating effect Effects 0.000 claims description 4
- 238000004321 preservation Methods 0.000 abstract description 6
- 230000009471 action Effects 0.000 abstract description 3
- 238000000034 method Methods 0.000 description 7
- 101000942297 Homo sapiens C-type lectin domain family 11 member A Proteins 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 150000001413 amino acids Chemical class 0.000 description 3
- 210000001185 bone marrow Anatomy 0.000 description 3
- 108090000342 C-Type Lectins Proteins 0.000 description 2
- 102000003930 C-Type Lectins Human genes 0.000 description 2
- 108091027974 Mature messenger RNA Proteins 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 210000003743 erythrocyte Anatomy 0.000 description 2
- 230000003394 haemopoietic effect Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 108700024394 Exon Proteins 0.000 description 1
- 108091092195 Intron Proteins 0.000 description 1
- 108700026244 Open Reading Frames Proteins 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 210000004899 c-terminal region Anatomy 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000002889 endothelial cell Anatomy 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 210000003494 hepatocyte Anatomy 0.000 description 1
- 210000003917 human chromosome Anatomy 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 210000000557 podocyte Anatomy 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 210000002536 stromal cell Anatomy 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
Abstract
The invention relates to the technical field of stem cell cryopreservation, in particular to a cryopreservation device for culturing stem cell growth factors, which comprises a cryopreservation box body, wherein an upper interlayer plate and a lower interlayer plate are arranged in a cryopreservation area and a preservation area, a cylinder and a test tube groove are arranged in the upper interlayer plate, an auxiliary positioning mechanism is arranged in the test tube groove, magnetic blocks are symmetrically hinged in the cylinder, and the end faces of the two magnetic blocks are opposite to each other. According to the invention, the lifting mechanism is arranged in the freezing box body, and the test tube stored in the test tube groove can be ejected by controlling the starting of the lifting mechanism, so that a user can be prevented from taking out the test tube by hand directly, and the fingers are frostbitten, so that the safety is high; the invention has the advantages that the cylinder is arranged, the two magnetic blocks are hinged in the cylinder, and under the action of the magnetic force of the two magnetic blocks, a closed space can be formed when the two magnetic blocks are not stressed, so that the air in the test tube groove is prevented from contacting with the outside, and the normal culture of stem cell growth factors in the test tube groove is prevented from being influenced.
Description
Technical Field
The invention relates to the technical field of stem cell cryopreservation, in particular to a cryopreservation device for culturing stem cell growth factors.
Background
Human stem cell growth factor (human stem cell growth factor, hsgf, also known as LSLCL) is an early hematopoietic stimulator that plays a role in the hematopoietic microenvironment of bone marrow, and has a variety of biological activities, mainly distributed in the brain, liver, bone marrow, placenta, testis, kidney, etc., produced by stromal cells, fibroblasts, endothelial cells, egg cells, podocytes, hepatocytes, etc., in these tissues (especially bone marrow). Its gene is localized to human chromosome 19q13.3, assembled from 4 exons and 3 introns. Human stem cell growth factor is known to have two forms, full length molecular hSCGF- α (mature mRNA full open reading frame 972bp, coding 323 amino acids, expressed protein size of about 45 KDa) and deletion of 78 amino acids (Epo) within the C-terminal conserved ca2+ -dependent sugar recognition domain (calcium dependent carbohydrate recognition domain, CRD), truncated molecular hSCGF- β (mature mRNA 738bp long, coding 245 amino acids) that synergistically has erythrocyte burst promoting activity on erythrocyte lines, and thus belongs to a C-type lectin (C-type lectin) superfamily member.
The stem cell growth factor needs to be frozen by a freezing device in the preservation process, so that the stem cell growth factor can be taken out at any time in the later period. In actual use, the conventional frozen storage device for the cell human stem cell growth factors is inconvenient to take out test tubes from the test tube grooves due to low temperature in the frozen storage device, the test tubes are forcibly manually extracted from the test tube grooves, fingers are easily frosted, and certain potential safety hazards exist; and current test tube is placing after the test tube groove, because the top of test tube groove needs place constantly or take out the test tube, consequently the top of test tube groove is the opening setting, and the test tube groove that the opening set up, leads to the inside temperature of test tube groove to switch on with outside temperature easily, influences the inside temperature of test tube groove, and then influences the inside freezing condition of test tube groove, has certain limitation.
Disclosure of Invention
The invention mainly aims to provide a cryopreservation device for culturing stem cell growth factors, which aims to solve the problems that when the existing stem cell growth factor cryopreservation device is used for storing and taking test tubes, the temperature in the cryopreservation device is low, so that the test tubes are inconvenient to take out from test tube grooves, the test tubes are forcibly manually extracted from the test tube grooves, and fingers are easy to be frostbitten; and the top of the test tube groove of the existing stem cell growth factor cryopreserving device is provided with an opening, so that the temperature inside the test tube groove is influenced, and the cryopreserving condition inside the test tube groove is further influenced.
In order to achieve the above object, the present invention provides the following techniques:
the utility model provides a cultivate stem cell growth factor's cryopreservation device, includes the cryopreservation box body, the centre of cryopreservation box body is run through and is installed the baffle, the both sides of cryopreservation box body are equipped with cryopreservation area and fresh-keeping district, the cryopreservation area is kept apart through the baffle with the fresh-keeping district:
an upper interlayer plate and a lower interlayer plate are arranged in the freezing area and the fresh-keeping area, a cylinder and a test tube groove are arranged in the upper interlayer plate, an auxiliary positioning mechanism is arranged in the test tube groove, magnetic blocks are symmetrically hinged in the cylinder, and the end surfaces of the two magnetic blocks are opposite to each other;
lifting mechanisms are arranged in the freezing area and the fresh-keeping area, the lifting mechanisms are arranged below the lower partition plate, and the lifting mechanisms are matched with the test tube grooves.
Further, a sealing cover is hinged to one side of the top end of the freezing box body, two observation windows are arranged on the side face of the freezing box body, and the two observation windows are used for observing the inside of the freezing area and the inside of the fresh-keeping area respectively.
Further, the inside of the cylinder is hinged with a hinge part, the magnetic block is arranged on the hinge part, the inner diameter of the cylinder is half of the diameter of the bottom surface of the test tube groove, and the test tube groove is provided with a plurality of cold air inlets.
Further, the auxiliary positioning mechanism comprises a reset spring and a clamp, wherein the reset spring is abutted between the clamp and the inner wall of the test tube groove, the clamp is in an arc-shaped arrangement, and a protection pad is embedded in the inner side of the clamp.
Further, the refrigerator and the temperature controller are respectively arranged in the freezing area and the fresh-keeping area, the refrigerator and the temperature controller are respectively arranged on the lower partition plate in the freezing area and the fresh-keeping area, and the freezing box body is provided with two control switches which are respectively electrically connected with the refrigerator and the temperature controller.
Further, elevating system includes jacking cylinder, polished rod, fagging and jacking piece, the inside bottom at the cryopreserved box body is installed to the jacking cylinder, the polished rod is equipped with many, and many polished rods are installed between the inside bottom and the lower division board of cryopreserved box body, fagging slidable mounting is on the polished rod, the bottom of fagging with the jacking cylinder output meets, the both ends at the fagging are installed to the jacking piece.
Further, a through hole is formed in the bottom end of the inside of the test tube groove, the through hole penetrates through the lower partition plate, and the jacking block moves in the through hole.
Compared with the prior art, the invention can bring the following technical effects:
1. according to the invention, the lifting mechanism is arranged in the freezing box body, and the test tube stored in the test tube groove can be ejected by controlling the starting of the lifting mechanism, so that a user can be prevented from taking out the test tube by hand directly, and the fingers are frostbitten, so that the safety is high;
2. according to the invention, the cylinder is arranged, and the two magnetic blocks are hinged in the cylinder, so that the two magnetic blocks can be mutually adsorbed under the action of magnetic force of the two magnetic blocks, and a closed space can be formed, so that the air in the test tube groove is prevented from contacting with the outside, and the normal culture of stem cell growth factors in the test tube groove is prevented from being influenced; under the condition of stress, the two magnetic blocks can be hinged to be folded up and down, so that the test tube can be conveniently stored in the test tube groove;
3. the invention has relatively low manufacturing cost, is convenient for the operation of users and has high safety.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention, are incorporated in and constitute a part of this specification. The drawings and their description are illustrative of the invention and are not to be construed as unduly limiting the invention. In the drawings:
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a schematic overall cross-sectional view of the present invention;
FIG. 3 is a schematic cross-sectional connection of a test tube well in accordance with the present invention.
In the figure: 1-cryopreservation box body, 2-sealing cover, 3-cryopreservation area, 4-fresh-keeping area, 5-cylinder, 6-magnetic block, 7-observation window, 8-elevating system, 801-jacking cylinder, 802-polished rod, 803-supporting plate, 804-jacking block, 9-upper partition plate, 10-partition plate, 11-refrigerator, 12-test tube slot, 1201-reset spring, 1202-clip, 13-temperature controller, 14-hinge, 15-control switch, 16-lower partition plate.
Detailed Description
In order that those skilled in the art will better understand the present invention, a technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in which it is apparent that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the present invention without making any inventive effort, shall fall within the scope of the present invention.
It should be noted that the terms "first," "second," and the like in the description and the claims of the present invention and the above figures are used for distinguishing between similar objects and not necessarily for describing a particular sequential or chronological order. It is to be understood that the data so used may be interchanged where appropriate in order to describe the embodiments of the invention herein. Furthermore, the terms "comprises," "comprising," and "having," and any variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements expressly listed but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus.
In the present invention, the terms "upper", "lower", "left", "right", "front", "rear", "top", "bottom", "inner", "outer", "middle", "vertical", "horizontal", "lateral", "longitudinal" and the like indicate an azimuth or a positional relationship based on that shown in the drawings. These terms are only used to better describe the present invention and its embodiments and are not intended to limit the scope of the indicated devices, elements or components to the particular orientations or to configure and operate in the particular orientations.
Also, some of the terms described above may be used to indicate other meanings in addition to orientation or positional relationships, for example, the term "upper" may also be used to indicate some sort of attachment or connection in some cases. The specific meaning of these terms in the present invention will be understood by those of ordinary skill in the art according to the specific circumstances.
In addition, the term "plurality" shall mean two as well as more than two.
It should be noted that, without conflict, the embodiments of the present invention and features of the embodiments may be combined with each other. The invention will be described in detail below with reference to the drawings in connection with embodiments.
The embodiment 1, a cryopreservation device for culturing stem cell growth factors, comprises a cryopreservation box body 1, wherein a partition board 10 is arranged in the middle of the cryopreservation box body 1 in a penetrating manner, a cryopreservation area 3 and a preservation area 4 are arranged at two sides of the cryopreservation box body 1, the cryopreservation area 3 and the preservation area 4 are isolated by the partition board 10, an upper interlayer plate 9 and a lower interlayer plate 16 are arranged in each of the cryopreservation area 3 and the preservation area 4, a cylinder 5 and a test tube groove 12 are arranged in each of the upper interlayer plates 9, an auxiliary positioning mechanism is arranged in each test tube groove 12, magnetic blocks 6 are symmetrically hinged in the cylinder 5, and the end faces of the two magnetic blocks 6 are opposite; lifting mechanisms 8 are arranged in the freezing storage area 3 and the fresh-keeping area 4, the lifting mechanisms 8 are arranged below the lower partition plate 16, and the lifting mechanisms 8 are matched with the test tube grooves 12;
the magnetic blocks 6 are symmetrically hinged in the cylinder 5, and the end surfaces of the two magnetic blocks 6 are opposite to each other, so that after a test tube is put into the test tube groove 12 or taken out from the test tube groove 12, the two magnetic blocks 6 can be automatically closed under the action of magnetic force, and further, the air in the test tube groove 12 can be prevented from contacting with the outside, the stem cell growth factors in the test tube are influenced, and the stem cell growth factors are effectively stored;
through setting up elevating system 8, through the start-up of control elevating system 8, can make the test tube that places in test tube groove 12 upward movement, and then can make the top of test tube outstanding, the user of being convenient for takes out the test tube through other instruments.
In the embodiment 2, the inner side of the cylinder 5 is hinged with a hinge piece 14, the magnetic block 6 is arranged on the hinge piece 14, the inner diameter of the cylinder 5 is half of the diameter of the bottom surface of the test tube groove 12, and a plurality of cold air inlets are formed in the test tube groove 12; the auxiliary positioning mechanism comprises a return spring 1201 and a clamp 1202, wherein the return spring 1201 is abutted between the clamp 1202 and the inner wall of the test tube groove 12, the clamp 1202 is arranged in an arc shape, and a protection pad is embedded in the inner side of the clamp 1202; the refrigerator 11 and the temperature controller 13 are respectively arranged in the freezing region 3 and the fresh-keeping region 4, the refrigerator 11 and the temperature controller 13 are respectively arranged on a lower partition plate 16 in the freezing region 3 and the fresh-keeping region 4, two control switches 15 are arranged on the freezing box body 1, and the two control switches 15 are respectively electrically connected with the refrigerator 11 and the temperature controller 13;
the inside of the cylinder 5 is hinged with the magnetic block 6 through the hinge piece 14, so that the magnetic block 6 can be folded up and down under the condition of being stressed, a test tube can be conveniently placed in the test tube groove 12, the inside of the test tube groove 12 can be isolated from the outside air through the magnetic block 6, the stem cell growth factors in the test tube are prevented from being corroded, and the safety is high; the clamp 1202 and the reset spring 1201 are arranged in the test tube groove 12, so that the test tube stored in the test tube groove 12 can be temporarily positioned, and can be lifted under the condition of stress, so that the test tube can be stored conveniently; through the setting of refrigerator 11 and temperature controller 13, can carry out the control of temperature to freezing storage district 3 and fresh-keeping district 4 inside, guarantee stem cell growth factor's the preservation to the maximum extent.
In embodiment 3, the lifting mechanism 8 includes a lifting cylinder 801, a polished rod 802, a supporting plate 803 and a lifting block 804, wherein the lifting cylinder 801 is installed at the inner bottom end of the freezing box 1, the polished rod 802 is provided with a plurality of polished rods 802, the polished rods 802 are installed between the inner bottom end of the freezing box 1 and the lower interlayer plate 16, the supporting plate 803 is slidably installed on the polished rod 802, the bottom end of the supporting plate 803 is connected with the output end of the lifting cylinder 801, and the lifting block 804 is installed at two ends of the supporting plate 803; a through hole is formed in the bottom end of the test tube tank 12, the through hole penetrates through the lower partition plate 16, and the jacking block 804 moves in the through hole;
the lifting cylinder 801 can be controlled, so that the lifting cylinder 801 drives the supporting plate 803 to lift, then the lifting of the supporting plate 803 can be achieved, the lifting block 804 is driven to lift, the test tube in the test tube groove 12 is conveniently driven to lift, the test tube can be conveniently taken and stored, and meanwhile, the supporting plate 803 can be stably lifted in the lifting process through the arrangement of the polish rods 802.
The above description is only of the preferred embodiments of the present invention and is not intended to limit the present invention, but various modifications and variations can be made to the present invention by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (4)
1. The utility model provides a cultivate cryopreservation device of stem cell growth factor, includes freezes and deposits box body (1), install baffle (10) in the centre of freezes and deposits box body (1), the both sides of freezes and deposits box body (1) are equipped with freezes and deposit district (3) and fresh-keeping district (4), freezes to deposit district (3) and keep fresh district (4) and keep apart its characterized in that through baffle (10):
an upper interlayer plate (9) and a lower interlayer plate (16) are arranged in the freezing and preserving area (3) and the preserving area (4), a cylinder (5) and a test tube groove (12) are arranged in the upper interlayer plate (9), an auxiliary positioning mechanism is arranged in the test tube groove (12), magnetic blocks (6) are symmetrically hinged in the cylinder (5), and the end faces of the two magnetic blocks (6) are opposite to each other;
lifting mechanisms (8) are arranged in the freezing storage area (3) and the fresh-keeping area (4), the lifting mechanisms (8) are arranged below the lower partition plate (16), and the lifting mechanisms (8) are matched with the test tube grooves (12);
the inner side of the cylinder (5) is hinged with a hinge piece (14), the magnetic block (6) is arranged on the hinge piece (14), the inner diameter of the cylinder (5) is half of the diameter of the bottom surface of the test tube groove (12), and a plurality of cold air inlets are formed in the test tube groove (12);
the refrigerator is characterized in that a refrigerator (11) and a temperature controller (13) are respectively arranged in the freezing region (3) and the fresh-keeping region (4), the refrigerator (11) and the temperature controller (13) are respectively arranged on a lower partition plate (16) in the freezing region (3) and the fresh-keeping region (4), two control switches (15) are arranged on the freezing box body (1), and the two control switches (15) are respectively electrically connected with the refrigerator (11) and the temperature controller (13);
elevating system (8) are including jacking cylinder (801), polished rod (802), fagging (803) and jacking piece (804), inside bottom at freezing box body (1) is installed to jacking cylinder (801), polished rod (802) are equipped with many, and many polished rods (802) are installed between the inside bottom of freezing box body (1) and lower division board (16), fagging (803) slidable mounting is on polished rod (802), the bottom of fagging (803) with jacking cylinder (801) output meets, both ends at fagging (803) are installed to jacking piece (804).
2. The cryopreservation device for culturing stem cell growth factors according to claim 1, wherein a cover (2) is hinged to one side of the top end of the cryopreservation box body (1), two observation windows (7) are installed on the side surface of the cryopreservation box body (1), and the two observation windows (7) are respectively used for observing the insides of the cryopreservation area (3) and the fresh-keeping area (4).
3. The cryopreservation apparatus for culturing stem cell growth factors according to claim 1, wherein the auxiliary positioning mechanism comprises a return spring (1201) and a clamp (1202), the return spring (1201) is abutted between the clamp (1202) and the inner wall of the test tube groove (12), the clamp (1202) is arc-shaped, and a protection pad is embedded in the inner side of the clamp (1202).
4. The cryopreservation apparatus for culturing stem cell growth factors according to claim 1, wherein a through hole is formed at the inner bottom end of the test tube well (12), the through hole penetrates through the lower partition plate (16), and the jacking block (804) moves in the through hole.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111232157.3A CN114805529B (en) | 2021-10-22 | 2021-10-22 | Freezing storage device for culturing stem cell growth factors |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111232157.3A CN114805529B (en) | 2021-10-22 | 2021-10-22 | Freezing storage device for culturing stem cell growth factors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114805529A CN114805529A (en) | 2022-07-29 |
| CN114805529B true CN114805529B (en) | 2024-03-12 |
Family
ID=82526874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111232157.3A Active CN114805529B (en) | 2021-10-22 | 2021-10-22 | Freezing storage device for culturing stem cell growth factors |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114805529B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115428787B (en) * | 2022-09-29 | 2023-10-13 | 邵阳学院 | Freezing device for researching cell culture based on molecular biological DNA |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN206314485U (en) * | 2016-12-24 | 2017-07-11 | 云南新生命干细胞有限公司 | A kind of stem cell cryopreserving frame |
| CN206871642U (en) * | 2017-03-28 | 2018-01-12 | 北京普利智诚生物技术有限公司 | A kind of novel paper cell cryopreservation box |
| CN211430784U (en) * | 2019-09-04 | 2020-09-08 | 上海联衡生物科技有限公司 | Stem cell growth factor cryopreservation device |
| CN211672141U (en) * | 2020-01-09 | 2020-10-16 | 上海奕杉生物科技有限公司 | Cell cryopreservation tube |
| CN212381993U (en) * | 2020-05-14 | 2021-01-22 | 天津市津华生物科技有限公司 | Stem cell cryopreservation device for biotechnology |
| CN212606701U (en) * | 2020-06-03 | 2021-02-26 | 南京帝准生物科技有限公司 | Lifting type biological gene detection kit |
| CN213281281U (en) * | 2020-08-07 | 2021-05-28 | 江苏育瑞康生物科技有限公司 | Cell freezing and transporting device |
| CN213736403U (en) * | 2020-12-03 | 2021-07-20 | 南方医科大学南方医院 | Freezing check unit and sample freezing device |
| CN113212936A (en) * | 2021-04-27 | 2021-08-06 | 曹高博 | Cell transportation is shifted and is deposited case with low temperature freezing |
| CN214183227U (en) * | 2020-11-30 | 2021-09-14 | 刘程 | Test-tube rack is used in inspection of medical science blood sample |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2018214954B2 (en) * | 2017-02-01 | 2023-07-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Devices for tissue cryopreservation and recovery |
-
2021
- 2021-10-22 CN CN202111232157.3A patent/CN114805529B/en active Active
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN206314485U (en) * | 2016-12-24 | 2017-07-11 | 云南新生命干细胞有限公司 | A kind of stem cell cryopreserving frame |
| CN206871642U (en) * | 2017-03-28 | 2018-01-12 | 北京普利智诚生物技术有限公司 | A kind of novel paper cell cryopreservation box |
| CN211430784U (en) * | 2019-09-04 | 2020-09-08 | 上海联衡生物科技有限公司 | Stem cell growth factor cryopreservation device |
| CN211672141U (en) * | 2020-01-09 | 2020-10-16 | 上海奕杉生物科技有限公司 | Cell cryopreservation tube |
| CN212381993U (en) * | 2020-05-14 | 2021-01-22 | 天津市津华生物科技有限公司 | Stem cell cryopreservation device for biotechnology |
| CN212606701U (en) * | 2020-06-03 | 2021-02-26 | 南京帝准生物科技有限公司 | Lifting type biological gene detection kit |
| CN213281281U (en) * | 2020-08-07 | 2021-05-28 | 江苏育瑞康生物科技有限公司 | Cell freezing and transporting device |
| CN214183227U (en) * | 2020-11-30 | 2021-09-14 | 刘程 | Test-tube rack is used in inspection of medical science blood sample |
| CN213736403U (en) * | 2020-12-03 | 2021-07-20 | 南方医科大学南方医院 | Freezing check unit and sample freezing device |
| CN113212936A (en) * | 2021-04-27 | 2021-08-06 | 曹高博 | Cell transportation is shifted and is deposited case with low temperature freezing |
Non-Patent Citations (2)
| Title |
|---|
| Development of a Directional Solidification Device for Cell Cryopreservation;Gao等;Cell Reservation Technology;第01卷(第04期);231-238 * |
| 人结合上皮细胞体外培养与冻存方法的改良;李树波等;上海口腔医学;第16卷(第03期);263-267 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN114805529A (en) | 2022-07-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN114805529B (en) | Freezing storage device for culturing stem cell growth factors | |
| CN109497040B (en) | Human oocyte and embryo vitrification freezing and thawing device and application method thereof | |
| CN213523623U (en) | Cell strain cryopreservation device | |
| CN205132086U (en) | Constant temperature kit | |
| CN211643075U (en) | Medical treatment is storage device for blood detection | |
| CN215422473U (en) | Liquid nitrogen quick freezing device for frozen section tissue | |
| CN211861627U (en) | Biological tissue sample freezing container | |
| CN211458672U (en) | Cryopreserved cell transfer device | |
| CN213355510U (en) | Animal blood storage device with temperature control function | |
| CN209555392U (en) | Constant temperature electrophoresis control device | |
| CN208360739U (en) | One kind is separable to freeze frame | |
| CN210470813U (en) | Amnion tissue cryopreservation tank | |
| CN216392816U (en) | Pear crossbreeding pollen save set | |
| CN216710028U (en) | Cell storage device for biological sample library | |
| CN212172946U (en) | Blood sample case | |
| CN215224294U (en) | Program cooling box for biological sample | |
| CN219044509U (en) | Storage box for extracting dental pulp stem cells | |
| CN218303110U (en) | A quick cryopreserving device of hemopoietic stem cell for skin is restoreed | |
| CN220454025U (en) | Ultralow temperature refrigerator for serum | |
| CN217937030U (en) | Novel embryo vitrification freezing operation device | |
| CN219125210U (en) | Program cooling box suitable for animal tissue sample | |
| CN214903387U (en) | Movable freezing storage box for stem cells | |
| CN212253220U (en) | Prevent embedding frame of embedding wax piece frost crack | |
| CN219990035U (en) | Storage box for placing frozen seminiferous tubules | |
| CN215246412U (en) | Protective device for serum-free rapid cell cold storage liquid |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |