CN114805529A - Culture stem cell growth factor's cryopreserving device - Google Patents
Culture stem cell growth factor's cryopreserving device Download PDFInfo
- Publication number
- CN114805529A CN114805529A CN202111232157.3A CN202111232157A CN114805529A CN 114805529 A CN114805529 A CN 114805529A CN 202111232157 A CN202111232157 A CN 202111232157A CN 114805529 A CN114805529 A CN 114805529A
- Authority
- CN
- China
- Prior art keywords
- test tube
- cryopreservation
- cylinder
- box body
- stem cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102100032528 C-type lectin domain family 11 member A Human genes 0.000 title claims abstract description 14
- 101710167766 C-type lectin domain family 11 member A Proteins 0.000 title claims abstract description 13
- 238000005138 cryopreservation Methods 0.000 claims abstract description 34
- 238000007710 freezing Methods 0.000 claims abstract description 25
- 230000008014 freezing Effects 0.000 claims abstract description 23
- 239000011229 interlayer Substances 0.000 claims abstract description 23
- 230000007246 mechanism Effects 0.000 claims abstract description 17
- 210000000130 stem cell Anatomy 0.000 claims abstract description 12
- 238000003860 storage Methods 0.000 claims abstract description 11
- 238000012258 culturing Methods 0.000 claims abstract description 10
- 239000003102 growth factor Substances 0.000 claims abstract description 10
- 230000010261 cell growth Effects 0.000 claims abstract description 7
- 238000004321 preservation Methods 0.000 claims abstract description 7
- 230000003028 elevating effect Effects 0.000 claims description 9
- 238000000151 deposition Methods 0.000 claims description 5
- 238000007789 sealing Methods 0.000 claims description 3
- 230000001681 protective effect Effects 0.000 claims description 2
- 230000009471 action Effects 0.000 abstract description 3
- 238000000034 method Methods 0.000 description 7
- 101000942297 Homo sapiens C-type lectin domain family 11 member A Proteins 0.000 description 4
- 150000001413 amino acids Chemical class 0.000 description 3
- 210000001185 bone marrow Anatomy 0.000 description 3
- 238000005192 partition Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 108090000342 C-Type Lectins Proteins 0.000 description 2
- 102000003930 C-Type Lectins Human genes 0.000 description 2
- 108091027974 Mature messenger RNA Proteins 0.000 description 2
- 230000000925 erythroid effect Effects 0.000 description 2
- 230000003394 haemopoietic effect Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- -1 Ca2+ Carbohydrate Chemical class 0.000 description 1
- 108700024394 Exon Proteins 0.000 description 1
- 108091092195 Intron Proteins 0.000 description 1
- 108700026244 Open Reading Frames Proteins 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 210000004899 c-terminal region Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 210000002889 endothelial cell Anatomy 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 210000003494 hepatocyte Anatomy 0.000 description 1
- 210000003917 human chromosome Anatomy 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 210000004681 ovum Anatomy 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 210000000557 podocyte Anatomy 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 210000002536 stromal cell Anatomy 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention relates to the technical field of stem cell cryopreservation, in particular to a cryopreservation device for culturing stem cell growth factors, which comprises a cryopreservation box body, wherein an upper interlayer plate and a lower interlayer plate are respectively arranged in a cryopreservation area and a preservation area, a cylinder and a test tube groove are arranged in the upper interlayer plate, an auxiliary positioning mechanism is arranged in the test tube groove, magnetic blocks are symmetrically hinged in the cylinder, and the end surfaces of the two magnetic blocks are attracted in an opposite way. According to the invention, the lifting mechanism is arranged in the freezing storage box body, and the test tube stored in the test tube groove can be ejected out by controlling the starting of the lifting mechanism, so that a user can be prevented from directly taking out the test tube by hands, fingers are frostbitten, and the safety is high; according to the invention, the cylinder is arranged and the two magnetic blocks are hinged in the cylinder, so that under the action of the magnetic force of the two magnetic blocks, a closed space can be formed when the two magnetic blocks are not stressed, and the influence of the contact of air in the test tube groove and the outside on the normal culture of the stem cell growth factor in the test tube groove is avoided.
Description
Technical Field
The invention relates to the technical field of stem cell cryopreservation, in particular to a cryopreservation device for culturing stem cell growth factors.
Background
Human stem cell growth factor (hSCGF, also known as LSLCL) is an early hematopoietic stimulator that functions in the bone marrow hematopoietic microenvironment, has a variety of biological activities, is mainly distributed in the brain, liver, bone marrow, placenta, testis, kidney, etc., and is produced by stromal cells, fibroblasts, endothelial cells, ova, podocytes, and hepatocytes in these tissues (especially bone marrow). The gene is located on human chromosome 19q13.3 and is assembled by 4 exons and 3 introns. It is known that human stem cell growth factor has two forms, full length molecule hSCGF-alpha (mature mRNA complete open reading frame 972bp, encoding 323 amino acids, and the expressed protein size is about 45KDa) and deletion of 78 amino acids (erythropoetin, Epo) in C-terminal conserved Ca2+ Carbohydrate Recognition Domain (CRD), truncated molecule hSCGF-beta (mature mRNA length 738bp, encoding 245 amino acids) which has synergistic effect on erythroid burst promoting activity of erythroid lineage, thus belonging to C-type lectin (C-type lectin) superfamily members.
The stem cell growth factor is required to be frozen by using a freezing device in the storage process so as to be convenient for later-stage use at any time. In actual use of the conventional cell human stem cell growth factor cryopreservation device, due to the fact that the temperature inside the cryopreservation device is low, a test tube cannot be taken out of a test tube groove conveniently, the test tube is extracted from the test tube groove manually by force, fingers are easily frostbitten, and certain potential safety hazards exist; and current test tube is placing behind the test-tube slot, because the top in test-tube slot need be placed constantly or take out the test tube, therefore the top in test-tube slot is the opening setting, and the test-tube slot that the opening set up leads to the inside temperature of test-tube slot to put through with outside temperature mutually easily, influences the inside temperature of test-tube slot, and then influences the freezing condition of test-tube slot inside, has certain limitation.
Disclosure of Invention
The invention mainly aims to provide a cryopreservation device for culturing stem cell growth factors, which aims to solve the problems that when the conventional stem cell growth factor cryopreservation device is used for storing and taking test tubes, the test tubes are not convenient to take out from a test tube groove due to the lower temperature in the cryopreservation device, and the fingers are easily frozen due to the fact that the test tubes are forcibly and manually taken out from the test tube groove; and the top of the test tube groove of the existing stem cell growth factor cryopreservation device is in an opening setting, so that the temperature inside the test tube groove is influenced, and the problem of cryopreservation conditions inside the test tube groove is further influenced.
In order to achieve the above object, the present invention provides the following techniques:
the utility model provides a cultivate device of depositing frozen of stem cell growth factor, includes and freezes the box body, NK freezes the centre of depositing the box body and runs through and install the baffle, the both sides of freezing the box body are equipped with and freeze district and fresh-keeping district, it keeps apart through the baffle with fresh-keeping district to freeze the district:
an upper interlayer plate and a lower interlayer plate are respectively arranged in the freezing area and the fresh-keeping area, a cylinder and a test tube groove are arranged in the upper interlayer plate, an auxiliary positioning mechanism is arranged in the test tube groove, magnetic blocks are symmetrically hinged in the cylinder, and the end surfaces of the two magnetic blocks are opposite and attracted;
elevating system is all installed with the inside in fresh-keeping district in the freezing district, elevating system sets up the below of lower division board, elevating system sets up with the cooperation of test-tube groove.
Further, one side of the top end of the freezing storage box body is hinged with a sealing cover, two observation windows are installed on the side face of the freezing storage box body, and the two observation windows are respectively used for observing the freezing storage area and the fresh-keeping area.
Further, the inner side of the cylinder is hinged with a hinge piece, the magnetic block is installed on the hinge piece, the inner diameter of the cylinder is half of the diameter of the bottom surface of the test tube groove, and the test tube groove is provided with a plurality of cold air inlet holes.
Further, auxiliary positioning mechanism includes reset spring and clip, the reset spring butt at the clip with between the test tube inslot wall, the clip is the arc setting, just the inboard of clip is inlayed and is equipped with the protection and fills up.
Further, freezer and temperature controller are installed respectively to the inside in freezing district and fresh-keeping district, freezer and temperature controller are installed respectively on freezing district and fresh-keeping district's lower interlayer board, freeze and install two control switches on the box body of depositing, two control switches are connected with freezer and temperature controller electricity respectively.
Further, elevating system includes jacking cylinder, polished rod, fagging and jacking piece, the inside bottom of freezing the storage box body is installed to the jacking cylinder, the polished rod is equipped with many, and many polished rods are installed and are being frozen between the inside bottom of storage box body and the lower interlayer board, fagging slidable mounting is on the polished rod, the bottom of fagging with jacking cylinder output meets, the both ends at the fagging are installed to the jacking piece.
Furthermore, a through hole is formed in the bottom end of the inner portion of the test tube groove, the through hole penetrates through the lower interlayer plate, and the jacking block moves in the through hole.
Compared with the prior art, the invention can bring the following technical effects:
1. according to the invention, the lifting mechanism is arranged in the freezing storage box body, and the test tube stored in the test tube groove can be ejected out by controlling the starting of the lifting mechanism, so that a user can be prevented from directly taking out the test tube by hands, fingers are frostbitten, and the safety is high;
2. according to the invention, the cylinder is arranged and the two magnetic blocks are hinged in the cylinder, so that under the action of the magnetic forces of the two magnetic blocks, the two magnetic blocks can be mutually adsorbed when not stressed, and further a closed space can be formed, so that the phenomenon that the air in a test tube groove is contacted with the outside to influence the normal culture of the stem cell growth factor in the test tube groove is avoided; under the condition of stress, the two magnetic blocks can be folded up and down by hinging, so that the test tube can be conveniently stored in the test tube groove;
3. the invention has the advantages of relatively low manufacturing cost, convenient operation of users and high safety.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, are included to provide a further understanding of the invention and to enable other features, objects and advantages of the invention to be more fully apparent. The drawings and their description illustrate the invention by way of example and are not intended to limit the invention. In the drawings:
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is an overall cross-sectional schematic view of the present invention;
FIG. 3 is a schematic sectional view showing the connection of the test tube well according to the present invention.
In the figure: 1-freezing and storing box body, 2-sealing cover, 3-freezing and storing area, 4-fresh-keeping area, 5-cylinder, 6-magnetic block, 7-observation window, 8-lifting mechanism, 801-jacking cylinder, 802-polished rod, 803-supporting plate, 804-jacking block, 9-upper interlayer plate, 10-partition plate, 11-refrigerator, 12-test tube groove, 1201-reset spring, 1202-clamp, 13-temperature controller, 14-hinged piece, 15-control switch and 16-lower interlayer plate.
Detailed Description
In order to make the technical solutions of the present invention better understood, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that the terms "first," "second," and the like in the description and claims of the present invention and in the drawings described above are used for distinguishing between similar elements and not necessarily for describing a particular sequential or chronological order. It is to be understood that the data so used may be interchanged under appropriate circumstances in order to facilitate the description of the embodiments of the invention herein. Furthermore, the terms "comprises," "comprising," and "having," and any variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements expressly listed, but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus.
In the present invention, the terms "upper", "lower", "left", "right", "front", "rear", "top", "bottom", "inner", "outer", "center", "vertical", "horizontal", "lateral", "longitudinal", and the like indicate an orientation or positional relationship based on the orientation or positional relationship shown in the drawings. These terms are used primarily to better describe the invention and its embodiments and are not intended to limit the indicated devices, elements or components to a particular orientation or to be constructed and operated in a particular orientation.
Moreover, some of the above terms may be used to indicate other meanings besides the orientation or positional relationship, for example, the term "on" may also be used to indicate some kind of attachment or connection relationship in some cases. The specific meanings of these terms in the present invention can be understood by those skilled in the art as appropriate.
In addition, the term "plurality" shall mean two as well as more than two.
It should be noted that the embodiments and features of the embodiments of the present invention may be combined with each other without conflict. The present invention will be described in detail below with reference to the embodiments with reference to the attached drawings.
the magnetic blocks 6 are symmetrically hinged in the cylinder 5, the end faces of the two magnetic blocks 6 are opposite in attraction, so that after the test tube is placed into the test tube groove 12 or taken out of the test tube groove 12, the two magnetic blocks 6 are automatically closed under the action of magnetic force, air in the test tube groove 12 can be prevented from contacting with the outside, stem cell growth factors in the test tube are influenced, and the stem cell growth factors are effectively stored;
through setting up elevating system 8, through the start-up of controlling elevating system 8, can be so that place the test tube upward movement in test tube groove 12, and then can make the top of test tube outstanding, the user of being convenient for takes out the test tube through other instruments.
In embodiment 2, a hinge 14 is hinged to the inner side of the cylinder 5, the magnetic block 6 is mounted on the hinge 14, the inner diameter of the cylinder 5 is half of the diameter of the bottom surface of the test tube slot 12, and the test tube slot 12 is provided with a plurality of cold air inlet holes; the auxiliary positioning mechanism comprises a return spring 1201 and a clamp 1202, the return spring 1201 abuts between the clamp 1202 and the inner wall of the test tube slot 12, the clamp 1202 is arranged in an arc shape, and a protective pad is embedded on the inner side of the clamp 1202; a refrigerator 11 and a temperature controller 13 are respectively arranged in the freezing area 3 and the fresh-keeping area 4, the refrigerator 11 and the temperature controller 13 are respectively arranged on a lower interlayer plate 16 in the freezing area 3 and the fresh-keeping area 4, two control switches 15 are arranged on the freezing box body 1, and the two control switches 15 are respectively electrically connected with the refrigerator 11 and the temperature controller 13;
the magnetic block 6 is hinged to the inner side of the cylinder 5 through the hinge 14, so that the magnetic block 6 can be conveniently turned up and down under the condition of stress, a test tube can be conveniently placed in the test tube groove 12, air in the test tube groove 12 and the outside can be isolated through the magnetic block 6, the stem cell growth factor in the test tube is prevented from being corroded, and the safety is high; the clamp 1202 and the return spring 1201 are arranged in the test tube groove 12, so that a test tube stored in the test tube groove 12 can be temporarily positioned, and can be lifted and lowered under the condition of stress, and the test tube can be conveniently stored; through the setting of refrigerator 11 and temperature controller 13, can freezing the control of keeping fresh the inside temperature that carries on of district 3 and fresh-keeping district 4, guarantee stem cell growth factor's save to the at utmost.
In embodiment 3, the lifting mechanism 8 includes a lifting cylinder 801, a polish rod 802, a supporting plate 803 and a lifting block 804, the lifting cylinder 801 is installed at the bottom end inside the freezing storage box body 1, the polish rod 802 is provided with a plurality of polish rods 802, the polish rods 802 are installed between the bottom end inside the freezing storage box body 1 and the lower interlayer plate 16, the supporting plate 803 is installed on the polish rod 802 in a sliding manner, the bottom end of the supporting plate 803 is connected with the output end of the lifting cylinder 801, and the lifting block 804 is installed at two ends of the supporting plate 803; a through hole is formed in the bottom end of the interior of the test tube groove 12, the through hole penetrates through the lower interlayer plate 16, and the jacking block 804 moves in the through hole;
accessible control jacking cylinder 801 for jacking cylinder 801 drives fagging 803 and goes up and down, and then the lift of accessible fagging 803, drives jacking piece 804 and goes up and down, is convenient for drive the test tube in test tube groove 12 and goes up and down, and then can be convenient for get the test tube and deposit, through the setting of many polished rods 802, can make fagging 803 go up and down more stable lift in-process simultaneously.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (7)
1. The utility model provides a culture stem cell growth factor freeze and deposit device, includes and freezes and deposits box body (1), NK freezes the centre of depositing box body (1) and runs through and installs baffle (10), the both sides of freezing and depositing box body (1) are equipped with and freeze and deposit district (3) and fresh-keeping district (4), it keeps apart its characterized in that through baffle (10) to freeze and deposit district (3) and fresh-keeping district (4):
an upper interlayer plate (9) and a lower interlayer plate (16) are arranged in the freezing storage area (3) and the fresh-keeping area (4), a cylinder (5) and a test tube groove (12) are arranged in the upper interlayer plate (9), an auxiliary positioning mechanism is arranged in the test tube groove (12), magnetic blocks (6) are symmetrically hinged in the cylinder (5), and the end surfaces of the two magnetic blocks (6) are attracted in opposite directions;
elevating system (8) are all installed with the inside in fresh-keeping district (4) in freezing district (3), elevating system (8) set up the below of lower division board (16), elevating system (8) set up with test-tube groove (12) cooperation.
2. The cryopreservation device for culturing the stem cell growth factor according to claim 1, wherein a top end side of the cryopreservation box body (1) is hinged with a sealing cover (2), two observation windows (7) are installed on the side surface of the cryopreservation box body (1), and the two observation windows (7) are respectively used for observing the interiors of the cryopreservation area (3) and the preservation area (4).
3. The cryopreservation device for culturing the growth factors of the stem cells according to claim 1, wherein the inner side of the cylinder (5) is hinged with a hinge (14), the magnetic block (6) is installed on the hinge (14), the inner diameter of the cylinder (5) is half of the diameter of the bottom surface of the test tube slot (12), and a plurality of cold air inlet holes are formed on the test tube slot (12).
4. The cryopreservation device for culturing the stem cell growth factors as claimed in claim 1, wherein the auxiliary positioning mechanism comprises a return spring (1201) and a clamp (1202), the return spring (1201) abuts between the clamp (1202) and the inner wall of the test tube slot (12), the clamp (1202) is arranged in an arc shape, and a protective pad is embedded inside the clamp (1202).
5. The cryopreservation device for culturing the growth factor of the stem cells according to claim 1, wherein a refrigerator (11) and a temperature controller (13) are respectively installed inside the cryopreservation area (3) and the preservation area (4), the refrigerator (11) and the temperature controller (13) are respectively installed on a lower division plate (16) in the cryopreservation area (3) and the preservation area (4), two control switches (15) are installed on the cryopreservation box body (1), and the two control switches (15) are respectively electrically connected with the refrigerator (11) and the temperature controller (13).
6. The cryopreservation device for culturing the stem cell growth factor according to claim 1, wherein the lifting mechanism (8) comprises a jacking cylinder (801), a polish rod (802), a supporting plate (803) and a jacking block (804), the jacking cylinder (801) is installed at the inner bottom end of the cryopreservation box body (1), the polish rod (802) is provided with a plurality of polish rods (802), the polish rods (802) are installed between the inner bottom end of the cryopreservation box body (1) and the lower interlayer plate (16), the supporting plate (803) is slidably installed on the polish rod (802), the bottom end of the supporting plate (803) is connected with the output end of the jacking cylinder (801), and the jacking block (804) is installed at two ends of the supporting plate (803).
7. The cryopreservation device for culturing the growth factors of the stem cells according to claim 6, wherein the bottom end of the interior of the test tube tank (12) is provided with a through hole, the through hole penetrates through the lower interlayer plate (16), and the jacking block (804) moves in the through hole.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111232157.3A CN114805529B (en) | 2021-10-22 | 2021-10-22 | Freezing storage device for culturing stem cell growth factors |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111232157.3A CN114805529B (en) | 2021-10-22 | 2021-10-22 | Freezing storage device for culturing stem cell growth factors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114805529A true CN114805529A (en) | 2022-07-29 |
| CN114805529B CN114805529B (en) | 2024-03-12 |
Family
ID=82526874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111232157.3A Active CN114805529B (en) | 2021-10-22 | 2021-10-22 | Freezing storage device for culturing stem cell growth factors |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114805529B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115428787A (en) * | 2022-09-29 | 2022-12-06 | 邵阳学院 | Cryopreservation device for researching cell culture based on molecular biological DNA |
Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN206314485U (en) * | 2016-12-24 | 2017-07-11 | 云南新生命干细胞有限公司 | A kind of stem cell cryopreserving frame |
| CN206871642U (en) * | 2017-03-28 | 2018-01-12 | 北京普利智诚生物技术有限公司 | A kind of novel paper cell cryopreservation box |
| US20190343113A1 (en) * | 2017-02-01 | 2019-11-14 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Servi | Devices for tissue cryopreservation and recovery |
| CN211430784U (en) * | 2019-09-04 | 2020-09-08 | 上海联衡生物科技有限公司 | Stem cell growth factor cryopreservation device |
| CN211672141U (en) * | 2020-01-09 | 2020-10-16 | 上海奕杉生物科技有限公司 | Cell cryopreservation tube |
| CN212381993U (en) * | 2020-05-14 | 2021-01-22 | 天津市津华生物科技有限公司 | Stem cell cryopreservation device for biotechnology |
| CN212606701U (en) * | 2020-06-03 | 2021-02-26 | 南京帝准生物科技有限公司 | Lifting type biological gene detection kit |
| CN213281281U (en) * | 2020-08-07 | 2021-05-28 | 江苏育瑞康生物科技有限公司 | Cell freezing and transporting device |
| CN213736403U (en) * | 2020-12-03 | 2021-07-20 | 南方医科大学南方医院 | Freezing check unit and sample freezing device |
| CN113212936A (en) * | 2021-04-27 | 2021-08-06 | 曹高博 | Cell transportation is shifted and is deposited case with low temperature freezing |
| CN214183227U (en) * | 2020-11-30 | 2021-09-14 | 刘程 | Test-tube rack is used in inspection of medical science blood sample |
-
2021
- 2021-10-22 CN CN202111232157.3A patent/CN114805529B/en active Active
Patent Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN206314485U (en) * | 2016-12-24 | 2017-07-11 | 云南新生命干细胞有限公司 | A kind of stem cell cryopreserving frame |
| US20190343113A1 (en) * | 2017-02-01 | 2019-11-14 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Servi | Devices for tissue cryopreservation and recovery |
| CN206871642U (en) * | 2017-03-28 | 2018-01-12 | 北京普利智诚生物技术有限公司 | A kind of novel paper cell cryopreservation box |
| CN211430784U (en) * | 2019-09-04 | 2020-09-08 | 上海联衡生物科技有限公司 | Stem cell growth factor cryopreservation device |
| CN211672141U (en) * | 2020-01-09 | 2020-10-16 | 上海奕杉生物科技有限公司 | Cell cryopreservation tube |
| CN212381993U (en) * | 2020-05-14 | 2021-01-22 | 天津市津华生物科技有限公司 | Stem cell cryopreservation device for biotechnology |
| CN212606701U (en) * | 2020-06-03 | 2021-02-26 | 南京帝准生物科技有限公司 | Lifting type biological gene detection kit |
| CN213281281U (en) * | 2020-08-07 | 2021-05-28 | 江苏育瑞康生物科技有限公司 | Cell freezing and transporting device |
| CN214183227U (en) * | 2020-11-30 | 2021-09-14 | 刘程 | Test-tube rack is used in inspection of medical science blood sample |
| CN213736403U (en) * | 2020-12-03 | 2021-07-20 | 南方医科大学南方医院 | Freezing check unit and sample freezing device |
| CN113212936A (en) * | 2021-04-27 | 2021-08-06 | 曹高博 | Cell transportation is shifted and is deposited case with low temperature freezing |
Non-Patent Citations (2)
| Title |
|---|
| GAO等: "Development of a Directional Solidification Device for Cell Cryopreservation", CELL RESERVATION TECHNOLOGY, vol. 01, no. 04, pages 231 - 238 * |
| 李树波等: "人结合上皮细胞体外培养与冻存方法的改良", 上海口腔医学, vol. 16, no. 03, pages 263 - 267 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115428787A (en) * | 2022-09-29 | 2022-12-06 | 邵阳学院 | Cryopreservation device for researching cell culture based on molecular biological DNA |
| CN115428787B (en) * | 2022-09-29 | 2023-10-13 | 邵阳学院 | Freezing device for researching cell culture based on molecular biological DNA |
Also Published As
| Publication number | Publication date |
|---|---|
| CN114805529B (en) | 2024-03-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN114805529A (en) | Culture stem cell growth factor's cryopreserving device | |
| CN109094952B (en) | Special vehicle-mounted storage and transportation equipment for stem cells and bioactive preparations | |
| CN205132086U (en) | Constant temperature kit | |
| CN215324005U (en) | Stem cell storage protection extraction element | |
| CN211643075U (en) | Medical treatment is storage device for blood detection | |
| CN216862242U (en) | Paraffin section placing box | |
| CN211458672U (en) | Cryopreserved cell transfer device | |
| CN211612774U (en) | Freeze and deposit frame convenient to adjust | |
| CN212172946U (en) | Blood sample case | |
| CN208699551U (en) | A kind of cell cryopreservation kit | |
| CN208360739U (en) | One kind is separable to freeze frame | |
| CN210470813U (en) | Amnion tissue cryopreservation tank | |
| CN216710028U (en) | Cell storage device for biological sample library | |
| CN220454025U (en) | Ultralow temperature refrigerator for serum | |
| CN218303110U (en) | A quick cryopreserving device of hemopoietic stem cell for skin is restoreed | |
| CN210782699U (en) | A cryopreserved box for stem cell is deposited | |
| CN214903387U (en) | Movable freezing storage box for stem cells | |
| CN216392816U (en) | Pear crossbreeding pollen save set | |
| CN219044509U (en) | Storage box for extracting dental pulp stem cells | |
| CN213695473U (en) | Side-by-side storage type freezing storage pipe | |
| CN216375696U (en) | Biological stem cell storage culture reagent case | |
| CN219990035U (en) | Storage box for placing frozen seminiferous tubules | |
| CN221962695U (en) | Integrated cell cryopreserving device | |
| CN212253220U (en) | Prevent embedding frame of embedding wax piece frost crack | |
| CN218146659U (en) | Intelligence cell mar device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |