CN215852944U

CN215852944U - Portable stem cell cold-stored transfer device

Info

Publication number: CN215852944U
Application number: CN202122258755.XU
Authority: CN
Inventors: 侯道荣; 鲍丹; 付鹤玲; 朱信强; 戴有金
Original assignee: Nanjing Medical University
Current assignee: Nanjing Medical University
Priority date: 2021-09-17
Filing date: 2021-09-17
Publication date: 2022-02-18
Anticipated expiration: 2031-09-17

Abstract

The utility model discloses a portable stem cell refrigerating and transferring device, and particularly relates to the technical field of refrigerating and transferring devices. According to the utility model, the refrigerating mechanism is arranged, the culture bottle filled with the culture solution and the stem cells is placed in the box body for storage, then the ice blocks are placed between the heat conducting plate and the fixing net in the box body through the box door, so that the heat in the box body is absorbed, the temperature in the box body is reduced, and the refrigerating purpose is achieved.

Description

Portable stem cell cold-stored transfer device

Technical Field

The utility model relates to the technical field of refrigeration transfer devices, in particular to a portable stem cell refrigeration transfer device.

Background

The stem cells are cells with unlimited or immortal self-renewal capacity, are primitive cells, can form various organs and tissues of human beings, can become various organs of human body, such as hearts, have problems due to the characteristics of the stem cells, and can be used for culturing a new heart in vitro.

The stem cells exist in various stages of life, play a very important role in growth, renewal and damage repair of the body, and also become the core of regenerative medicine, thereby providing theoretical basis and realistic hope for the complete cure of difficult and complicated diseases in the current medicine.

With the continuous progress of medical technology, stem cells have been applied to the treatment of some corresponding diseases, after being extracted from a human body, the stem cells need to be placed in a culture solution for refrigeration and preservation, ice cubes are generally used for cooling the stem cells in the process of transporting the stem cells, so that the purpose of refrigeration is achieved, however, the ice cubes are easy to melt in the process of cooling, and the culture solution in a culture bottle is easy to shake or even splash due to jolt in the transportation process, so that inconvenience is brought to transportation.

SUMMERY OF THE UTILITY MODEL

In order to overcome the above-mentioned drawbacks of the prior art, embodiments of the present invention provide a portable stem cell cryopreservation transfer device to solve the above-mentioned problems in the background art.

In order to achieve the purpose, the utility model provides the following technical scheme: a portable stem cell refrigerating and transferring device comprises a box body, wherein a refrigerating mechanism is arranged inside the box body;

refrigeration mechanism includes the baffle, the baffle is established inside the box, baffle outer end and box inner wall fixed connection, inlay on the baffle top has the semiconductor refrigeration piece, the fixed heat-conducting plate that is equipped with in baffle top, heat-conducting plate outer end and box inner wall fixed connection, semiconductor refrigeration piece top contacts with the heat-conducting plate.

Further, the inside bottom end of box is fixed and is equipped with two batteries, battery and semiconductor refrigeration piece electric connection, the radiator-grid has been inlayed to the baffle bottom, the radiator-grid top contacts with semiconductor refrigeration piece bottom, the fixed heat dissipation fan that is equipped with of box rear side, the heat dissipation fan is established in the baffle bottom, and the heat dissipation fan plays the additional action to the heat dissipation of semiconductor refrigeration piece.

Further, the inside fixed net that is equipped with of box, fixed net outer end and box inner wall fixed connection, the fixed net is established at the heat-conducting plate top, the box rear side is equipped with the chamber door and passes through hinge swing joint with the chamber door, the chamber door is established between heat-conducting plate and fixed net, and the ice-cube is put into the box through the chamber door.

Further, a plurality of sleeves are fixedly arranged at the top end of the fixing net, rubber pads are fixedly arranged on the inner walls of the sleeves, culture bottles are arranged inside the sleeves, the outer ends of the culture bottles are in contact with the inner sides of the rubber pads, the top ends of the culture bottles extend to the tops of the sleeves, sealing covers are sleeved at the top ends of the culture bottles and are in threaded connection with the sealing covers, sealing blocks are arranged inside the culture bottles, air bags are fixedly arranged at the outer ends of the sealing blocks, the outer ends of the air bags are in contact with the inner walls of the culture bottles, air guide pipes are fixedly arranged at the top ends of the sealing blocks, one ends of the air guide pipes extend to the tops of the sealing covers and are in threaded connection with the sealing covers, valves are fixedly arranged on the air guide pipes, the other ends of the air guide pipes extend to the bottom ends of the sealing blocks, two branch pipes are fixedly arranged inside the sealing blocks, and one ends of the branch pipes extend to the outer ends of the sealing blocks, the airway tube is in communication with the balloon via a branch tube, whereby gas enters the balloon and inflates it.

Further, the top end of the box body is provided with a top cover and connected with the top cover through a hasp, a control panel is fixedly arranged on the front side of the box body and electrically connected with the semiconductor refrigerating sheet, and therefore the semiconductor refrigerating sheet is adjusted and controlled.

Further, the top cap top is equipped with the connecting rod, the connecting rod top end is fixed and is equipped with the connector, the connector top end is equipped with the handle and passes through universal pivot swing joint with the handle, the fixed connecting band that all is equipped with in connecting rod both sides, two connecting band one end respectively with box both sides fixed connection to this mentions the box.

The utility model has the technical effects and advantages that:

1. according to the utility model, the refrigerating mechanism is arranged, the culture bottle filled with the culture solution and the stem cells is placed in the box body for storage, then the ice blocks are placed between the heat conducting plate and the fixing net in the box body through the box door, so that the heat in the box body is absorbed, the temperature in the box body is reduced, and the refrigerating purpose is achieved.

2. The culture solution and the stem cells are sealed at the bottom of the sealing block by the air bag, even if jolting occurs in the transportation process, the culture solution does not have too large shaking space due to the sealing block and the air bag, and the problem of splashing of the culture solution due to the fact that the culture solution is splashed is further avoided.

Drawings

Fig. 1 is a perspective view of the present invention.

Fig. 2 is a perspective view of the present invention.

FIG. 3 is a perspective semi-sectional view of the housing of the present invention.

FIG. 4 is a perspective half-sectional view of the culture flask of the present invention.

Fig. 5 is a perspective half-sectional view of the closure block of the present invention.

The reference signs are: 1. a box body; 2. a control panel; 3. a top cover; 4. a handle; 5. a connector; 6. a connecting rod; 7. a connecting belt; 8. a box door; 9. a heat dissipation fan; 10. a battery; 11. a partition plate; 12. a heat conducting plate; 13. fixing the net; 14. a sleeve; 15. a culture bottle; 16. a sealing cover; 17. a semiconductor refrigeration sheet; 18. a heat-dissipating web; 19. a rubber pad; 20. a sealing block; 21. an air bag; 22. an air duct; 23. and (4) branch pipes.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

With reference to the attached drawings 1-5 in the specification, the portable stem cell refrigerating and transferring device of the embodiment comprises a box body 1, wherein a refrigerating mechanism is arranged inside the box body 1;

the refrigeration mechanism comprises a partition plate 11, the partition plate 11 is arranged inside the box body 1, the outer end of the partition plate 11 is fixedly connected with the inner wall of the box body 1, a semiconductor refrigeration sheet 17 is inlaid at the top end of the partition plate 11, by utilizing the Peltier effect of semiconductor materials, when direct current passes through a galvanic couple formed by serially connecting two different semiconductor materials, heat can be absorbed and released at two ends of the galvanic couple respectively, the refrigeration purpose can be realized, so that the heat of ice blocks is absorbed through the semiconductor refrigeration sheet 17 to avoid melting of the ice blocks, a heat conduction plate 12 is fixedly arranged at the top end of the partition plate 11, the outer end of the heat conduction plate 12 is fixedly connected with the inner wall of the box body 1, the top end of the semiconductor refrigeration sheet 17 is contacted with the heat conduction plate 12, the heat conduction plate 12 can conduct heat, two batteries 10 are fixedly arranged at the bottom end inside the box body 1, the batteries 10 are electrically connected with the semiconductor refrigeration sheet 17, so as to supply electricity for the

semiconductor refrigeration sheet

17, 11 bottoms of baffle are inlayed and are had radiator-

grid

18, 18 tops of radiator-grid contact with 17 bottoms of semiconductor refrigeration piece, and the heat that produces in the 17 course of work of semiconductor refrigeration gives off with this, the fixed heat dissipation fan 9 that is equipped with of 1 rear side of box, heat dissipation fan 9 is established in 11 bottoms of baffle, and heat dissipation fan 9 plays the additional contribution to the heat dissipation of

semiconductor refrigeration piece

17, 1 inside solid fixed network 13 that is equipped with of box, solid fixed network 13 outer end and 1 inner wall fixed connection of box, solid fixed network 13 is established at 12 tops of heat-conducting plate, and the top at solid fixed network 13 is placed to

blake bottle

15, 1 rear side of box is equipped with chamber door 8 and passes through hinge swing joint with chamber door 8, chamber door 8 is established between heat-conducting plate 12 and solid fixed network 13, and the ice-cube is put into through chamber door 8 in the box 1.

The implementation scenario is specifically as follows: when in use, firstly, the box door 8 at the rear side of the box body 1 is opened, ice blocks are placed inside the box body 1 through the box door 8, therefore, the ice blocks are positioned between the heat conducting plate 12 and the fixing net 13 inside the box body 1, then, a culture bottle 15 filled with culture solution and stem cells is placed at the top end of the fixing net 13 and is fixed through the sleeve 14, then, the top cover 3 is covered, the inside of the box body 1 is sealed, the temperature in the box body 1 is reduced by the ice blocks, so as to achieve the purpose of refrigeration, in the process, the semiconductor refrigerating sheet 17 embedded at the top end of the partition plate 11 is electrified, the refrigerating end of the semiconductor refrigerating sheet 17 is contacted with the heat conducting plate 12, so as to absorb the heat of the ice blocks, avoid the ice blocks from melting in the transportation process, further maintain the refrigerating temperature inside the box body 1, and simultaneously, the hot end of the semiconductor refrigerating sheet 17 is contacted with the heat radiating net 18 downwards, so as to radiate the absorbed heat through the radiating net 18, still can be through the heat dissipation fan 9 of opening box 1 rear side, improve radiating efficiency, through setting up refrigeration mechanism, the blake bottle 15 that will be equipped with culture solution and stem cell is placed at box 1 inside and is stored, place the ice-cube between the inside heat-conducting plate 12 of box 1 and fixed network 13 through chamber door 8 afterwards, absorb the heat in box 1 with this, reduce the inside temperature of box 1, reach cold-stored purpose, it leads to the electricity to inlay the semiconductor refrigeration piece 17 on baffle 11 top simultaneously, utilize the heat of semiconductor refrigeration piece 17 absorption ice-cube, can avoid the ice-cube to melt and bring inconvenience for the transportation, also the cold-stored effect in the maintenance box 1 for a long time.

Referring to the attached drawings 1-5 in the specification, in the portable stem cell cold storage transfer device of this embodiment, a plurality of sleeves 14 are fixedly arranged at the top end of the fixing net 13, rubber pads 19 are fixedly arranged on the inner walls of the sleeves 14, culture bottles 15 are arranged inside the sleeves 14, the outer ends of the culture bottles 15 are in contact with the inner sides of the rubber pads 19, the rubber pads 19 have elasticity, so that the culture bottles 15 can be clamped and fixed in the sleeves 14, the top ends of the culture bottles 15 extend to the tops of the sleeves 14, seal covers 16 are sleeved at the top ends of the culture bottles 15 and are in threaded connection with the seal covers 16, seal blocks 20 are arranged inside the culture bottles 15, air bags 21 are fixedly arranged at the outer ends of the seal blocks 20, the outer ends of the air bags 21 are in contact with the inner walls of the culture bottles 15, so that culture solution is sealed at the bottoms of the seal blocks 20 by the air bags 21 and the seal blocks 20, air guide tubes 22 are fixedly arranged at the top ends of the seal blocks 20, one end of the air duct 22 extends to the top of the sealing cover 16 and is in threaded connection with the sealing cover 16, a valve is fixedly arranged on the air duct 22, so that the distance between the sealing block 20 and the liquid level is adjusted by rotating the air duct 22, the other end of the air duct 22 extends to the bottom end of the sealing block 20, two branch pipes 23 are fixedly arranged at the outer end of the air duct 22, the branch pipes 23 are fixedly arranged inside the sealing block 20, one end of each branch pipe 23 extends to the outer end of the sealing block 20, the air duct 22 is communicated with the air bag 21 through the branch pipes 23, gas enters the air bag 21 and expands the air bag, a top cover 3 is arranged at the top end of the box body 1 and is connected with the top cover 3 through a buckle, so that the box body 1 is sealed, a control panel 2 is fixedly arranged at the front side of the box body 1, and the control panel 2 is electrically connected with the semiconductor refrigeration sheet 17, so that the semiconductor refrigeration sheet 17 is adjusted and controlled, the top of the top cover 3 is provided with a connecting rod 6, the top of the connecting rod 6 is fixedly provided with a connector 5, the top of the connector 5 is provided with a handle 4 and is movably connected with the handle 4 through a universal rotating shaft, so that after the box body 1 is lifted, the box body 1 is always in a vertical state under the action of self gravity through the universal rotating shaft, the inclination cannot occur, the connecting rods 6 are fixedly provided with connecting bands 7 and two at two sides, one ends of the connecting bands 7 are respectively fixedly connected with two sides of the box body 1, and the box body 1 is lifted through the connecting bands.

The implementation scenario is specifically as follows: in the process of adding culture solution and stem cells into the culture bottle 15, firstly opening the sealing cover 16, placing the culture solution and stem cells into the culture bottle 15, then covering the sealing cover 16 on the top end of the culture bottle 15, at this time, the sealing block 20 is connected on the sealing cover 16 through the air duct 22 and is positioned above the liquid level inside the culture bottle 15, then rotating the air duct 22, as the air duct 22 is connected with the sealing cover 16 through screw threads, after the air duct 22 rotates, pushing the sealing block 20 to approach the liquid level, when the sealing block 20 is close to the liquid level to a certain degree, inflating the air duct 22, the air flows into the air bag 21 through the air duct 22 and the branch pipe 23, the air bag 21 is expanded and contacts with the inner wall of the culture bottle 15, when the air bag 21 is expanded to a certain degree, closing the valve on the air duct 22, so that the air bag 21 maintains the expanded state, thereby utilizing the air bag 21 to seal the culture solution and stem cells at the bottom of the sealing block 20, even if the culture solution jolts during transportation, the culture solution does not have too large shaking space due to the sealing block 20 and the air bag 21, and the problem that the culture solution is splashed due to the culture solution is avoided.

The points to be finally explained are: first, in the description of the present application, it should be noted that, unless otherwise specified and limited, the terms "mounted," "connected," and "connected" should be understood broadly, and may be a mechanical connection or an electrical connection, or a communication between two elements, and may be a direct connection, and "upper," "lower," "left," and "right" are only used to indicate a relative positional relationship, and when the absolute position of the object to be described is changed, the relative positional relationship may be changed;

secondly, the method comprises the following steps: in the drawings of the disclosed embodiments of the utility model, only the structures related to the disclosed embodiments are referred to, other structures can refer to common designs, and the same embodiment and different embodiments of the utility model can be combined with each other without conflict;

and finally: the above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the utility model, and any modifications, equivalents, improvements and the like that are within the spirit and principle of the present invention are intended to be included in the scope of the present invention.

Claims

1. The utility model provides a cold-stored transfer device of portable stem cell, includes box (1), its characterized in that: a refrigerating mechanism is arranged inside the box body (1);

refrigeration mechanism includes baffle (11), establish inside box (1) baffle (11), baffle (11) outer end and box (1) inner wall fixed connection, baffle (11) top is inlayed and is had semiconductor refrigeration piece (17), baffle (11) top is fixed and is equipped with heat-conducting plate (12), heat-conducting plate (12) outer end and box (1) inner wall fixed connection, semiconductor refrigeration piece (17) top contacts with heat-conducting plate (12).

2. The portable stem cell cryopreservation transfer device of claim 1, wherein: the inside bottom mounting of box (1) is equipped with two batteries (10), battery (10) and semiconductor refrigeration piece (17) electric connection, inlay in baffle (11) bottom has radiator-grid (18), radiator-grid (18) top contacts with semiconductor refrigeration piece (17) bottom, box (1) rear side is fixed to be equipped with heat dissipation fan (9), heat dissipation fan (9) are established in baffle (11) bottom.

3. The portable stem cell cryopreservation transfer device of claim 1, wherein: the improved refrigerator is characterized in that a fixing net (13) is arranged inside the refrigerator body (1), the outer end of the fixing net (13) is fixedly connected with the inner wall of the refrigerator body (1), the fixing net (13) is arranged at the top of the heat-conducting plate (12), the rear side of the refrigerator body (1) is provided with a refrigerator door (8) and movably connected with the refrigerator door (8) through a hinge, and the refrigerator door (8) is arranged between the heat-conducting plate (12) and the fixing net (13).

4. The portable stem cell cryopreservation transfer device of claim 3, wherein: the utility model discloses a culture flask, including fixed net (13), fixed net, rubber pad (14), sleeve (14), culture flask (15), sealed piece (20), gasbag (21) are fixed to be equipped with in the sealed top of flask (15), sealed lid (16) and pass through threaded connection with sealed lid (16) to fixed net (13) top is fixed to be equipped with a plurality of sleeves (14) on the sleeve (14) inner wall, the inside blake flask (15) outer end contacts with rubber pad (19) inboard, blake flask (15) top cover, sealed piece (15) inside is equipped with sealed piece (20), gasbag (21) outer end contacts with blake flask (15) inner wall, sealed piece (20) top is fixed to be equipped with air duct (22), air duct (22) one end extends to sealed lid (16) top and passes through threaded connection with sealed lid (16), the fixed valve that is equipped with on air duct (22), air duct (22) other end extends to sealed piece (20) bottom, air duct (22) outer end is fixed and is equipped with two branch pipes (23), branch pipe (23) are fixed to be established inside sealed piece (20), branch pipe (23) one end extends to sealed piece (20) outer end, air duct (22) are linked together through branch pipe (23) with gasbag (21).

5. The portable stem cell cryopreservation transfer device of claim 1, wherein: the refrigerator is characterized in that a top cover (3) is arranged at the top end of the refrigerator body (1) and connected with the top cover (3) through a hasp, a control panel (2) is fixedly arranged on the front side of the refrigerator body (1), and the control panel (2) is electrically connected with the semiconductor refrigerating sheet (17).

6. The portable stem cell cryopreservation transfer device of claim 5, wherein: top cap (3) top is equipped with connecting rod (6), connecting rod (6) top is fixed and is equipped with connector (5), connector (5) top be equipped with handle (4) and with handle (4) through universal pivot swing joint, connecting rod (6) both sides are fixed all to be equipped with connecting band (7), two connecting band (7) one end respectively with box (1) both sides fixed connection.