CN113195712B - 突变型piggyBac转座酶 - Google Patents

突变型piggyBac转座酶 Download PDF

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Publication number
CN113195712B
CN113195712B CN201980081292.7A CN201980081292A CN113195712B CN 113195712 B CN113195712 B CN 113195712B CN 201980081292 A CN201980081292 A CN 201980081292A CN 113195712 B CN113195712 B CN 113195712B
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seq
nucleic acid
piggybac transposase
cell
piggybac
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CN113195712A (zh
Inventor
N·J·阿拉瓦尔
K·M·达里斯
J·L·斯蒂芬斯
H·T·N·黎
N·B·塔拉文
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Amgen Inc
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Amgen Inc
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    • C12N9/1241—Nucleotidyltransferases (2.7.7)
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    • C12N2800/90—Vectors containing a transposable element

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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CN201980081292.7A 2018-12-10 2019-12-09 突变型piggyBac转座酶 Active CN113195712B (zh)

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US201862777325P 2018-12-10 2018-12-10
US62/777325 2018-12-10
US201962925516P 2019-10-24 2019-10-24
US62/925516 2019-10-24
PCT/US2019/065129 WO2020123327A1 (en) 2018-12-10 2019-12-09 Mutated piggybac transposase

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US20250027052A1 (en) 2023-07-21 2025-01-23 Amgen Inc. Vectors incorporating a combination of promoters driving selectable marker expression
WO2025096649A1 (en) 2023-11-01 2025-05-08 Immatics US, Inc. Membrane-bound il-15, cd8 polypeptides, cells, compositions, and methods of using thereof
CN120737218B (zh) * 2025-08-15 2026-01-06 云南彤宁生物制药技术有限公司 融合蛋白、调控系统及利用该系统构建转基因细胞的方法

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AU2019398101A1 (en) 2021-06-10
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JP2022512332A (ja) 2022-02-03
CL2023003339A1 (es) 2024-06-07
DK3894549T3 (da) 2024-10-14
LT3894549T (lt) 2024-09-25
EP3894549A1 (en) 2021-10-20
MX2021006783A (es) 2021-07-15
BR112021011063A2 (pt) 2021-08-31
PT3894549T (pt) 2024-10-16
US20220064610A1 (en) 2022-03-03
HUE068630T2 (hu) 2025-01-28
CN118995660A (zh) 2024-11-22
IL283314A (en) 2021-07-29
ES2991895T3 (es) 2024-12-05
US12570966B2 (en) 2026-03-10
KR20210101270A (ko) 2021-08-18
AU2026201887A1 (en) 2026-04-02
TW202035687A (zh) 2020-10-01
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