CN113149885A - Ebna1抑制剂和使用其的方法 - Google Patents

Ebna1抑制剂和使用其的方法 Download PDF

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Publication number
CN113149885A
CN113149885A CN202110223995.8A CN202110223995A CN113149885A CN 113149885 A CN113149885 A CN 113149885A CN 202110223995 A CN202110223995 A CN 202110223995A CN 113149885 A CN113149885 A CN 113149885A
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Prior art keywords
indol
benzoic acid
phenylethynyl
ethynyl
phenyl
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CN202110223995.8A
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Chinese (zh)
Inventor
T·E·麦塞科
G·R·史密斯
A·B·瑞兹
P·M·利伯曼
M·E·麦克唐纳
Y·张
M·卡森
S·陈
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Wistar Institute of Anatomy and Biology
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Wistar Institute of Anatomy and Biology
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Publication of CN113149885A publication Critical patent/CN113149885A/zh
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    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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CN114008049B (zh) 2019-06-21 2024-07-05 豪夫迈·罗氏有限公司 用于癌症治疗的egfr抑制剂
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