CN113117030A - Traditional Chinese medicine composition for treating pulmonary nodules and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating pulmonary nodules and preparation method thereof Download PDF

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CN113117030A
CN113117030A CN202110532940.5A CN202110532940A CN113117030A CN 113117030 A CN113117030 A CN 113117030A CN 202110532940 A CN202110532940 A CN 202110532940A CN 113117030 A CN113117030 A CN 113117030A
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traditional chinese
chinese medicine
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medicine composition
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冯高华
倪军
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Zhangjiagang Hospital of Traditional Chinese Medicine
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Zhangjiagang Hospital of Traditional Chinese Medicine
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Abstract

The invention discloses a traditional Chinese medicine composition for treating pulmonary nodules and a preparation method thereof. The traditional Chinese medicine composition comprises the following components in parts by weight: 6-12 parts of radix bupleuri, 10-20 parts of codonopsis pilosula, 10-20 parts of astragalus membranaceus, 6-12 parts of pericarpium citri reticulatae, 10-20 parts of poria cocos, 15-30 parts of coix seeds, 15-30 parts of Chinese sage herb, 10-20 parts of thunberg fritillary bulb, 6-12 parts of ligusticum wallichii, 15-30 parts of sculellaria barbata, 3-6 parts of cinnamon and 10-20 parts of bighead atractylodes rhizome. The traditional Chinese medicine composition can condition the viscera functions of patients with early pulmonary nodule formation, and has the function of cutting off the possibility of further development and deterioration of pulmonary nodules; for the patients with follow-up reexamination, the traditional Chinese medicine composition can improve the symptoms of the patients, smoothen the emotion of the patients, reduce the mental burden and improve the life quality.

Description

Traditional Chinese medicine composition for treating pulmonary nodules and preparation method thereof
Technical Field
The invention relates to the field of traditional Chinese medicine formulas, in particular to a traditional Chinese medicine composition for treating pulmonary nodules and a preparation method thereof.
Background
The imaging definition of a lung nodule is a small well-defined lesion (diameter ≦ 30 mm) completely surrounded by lung parenchyma. The form of the nodule is classified as solid or sub-solid; sub-solid nodules are further classified as pure ground glass nodules and partially solid nodules. Pulmonary nodules may be found in cross-sectional imaging examinations performed for unrelated reasons, i.e., sporadic pulmonary nodules. The early stage patient with the pulmonary nodules can be treated by the medicine, and the side effect of western medicine treatment is large, so that the traditional Chinese medicine composition for treating the pulmonary nodules is very necessary.
Disclosure of Invention
The invention aims to solve the technical problems and provides a traditional Chinese medicine composition for treating pulmonary nodules and a preparation method thereof.
The invention is realized by the following technical scheme.
A traditional Chinese medicine composition for treating pulmonary nodules comprises the following components in parts by weight: 6-12 parts of radix bupleuri, 10-20 parts of codonopsis pilosula, 10-20 parts of astragalus membranaceus, 6-12 parts of pericarpium citri reticulatae, 10-20 parts of poria cocos, 15-30 parts of coix seeds, 15-30 parts of Chinese sage herb, 10-20 parts of thunberg fritillary bulb, 6-12 parts of ligusticum wallichii, 15-30 parts of sculellaria barbata, 3-6 parts of cinnamon and 10-20 parts of bighead atractylodes rhizome.
Further, the traditional Chinese medicine composition for treating pulmonary nodules comprises the following components in parts by weight:
10 parts of radix bupleuri, 20 parts of codonopsis pilosula, 20 parts of astragalus membranaceus, 10 parts of pericarpium citri reticulatae, 10 parts of poria cocos, 20 parts of coix seeds, 20 parts of Chinese sage herb, 20 parts of thunberg fritillary bulb, 10 parts of ligusticum wallichii, 15 parts of sculellaria barbata, 5 parts of cinnamon and 10 parts of bighead atractylodes rhizome.
Further, the traditional Chinese medicine composition for treating pulmonary nodules comprises the following components in parts by weight:
10 parts of radix bupleuri, 20 parts of codonopsis pilosula, 20 parts of astragalus membranaceus, 10 parts of pericarpium citri reticulatae, 10 parts of poria cocos, 20 parts of coix seeds, 20 parts of Chinese sage herb, 20 parts of thunberg fritillary bulb, 10 parts of ligusticum wallichii, 15 parts of sculellaria barbata, 5 parts of cinnamon and 10 parts of bighead atractylodes rhizome.
A preparation method of the traditional Chinese medicine composition for treating pulmonary nodules comprises the following steps:
s1, weighing specified amounts of radix bupleuri, codonopsis pilosula, astragalus membranaceus, pericarpium citri reticulatae, poria cocos, coix seeds, Chinese sage herb, thunberg fritillary bulb, ligusticum wallichii, barbed skullcap herb, cinnamon and bighead atractylodes rhizome, soaking in water, adding water to submerge the medicine surface for 2-3cm, and soaking for 20-40 min;
s2, decocting the soaked medicinal materials, boiling for 20-30min, and collecting a first decoction;
s3, adding the same water amount as the first decoction into the traditional Chinese medicine, carrying out second decoction under the same condition as the first decoction, and collecting liquid medicine of the second decoction;
and S4, combining the first decoction and the second decoction to obtain the Chinese herbal medicine.
Further, in step S1, the temperature of the water for soaking the traditional Chinese medicine is 25-50 ℃.
The present application has the following advantageous effects.
The traditional Chinese medicine composition can condition the viscera functions of patients with early pulmonary nodule formation, and has the function of cutting off the possibility of further development and deterioration of pulmonary nodules; for the patients with follow-up reexamination, the traditional Chinese medicine composition can improve the symptoms of the patients, smoothen the emotion of the patients, reduce the mental burden and improve the life quality. The traditional Chinese medicine composition is reasonable and scientific in compatibility, has an excellent treatment effect, and meets the requirements of clinical treatment.
Detailed Description
Example 1
A preparation method of a traditional Chinese medicine composition for treating pulmonary nodules comprises the following steps:
s1, weighing 6g of radix bupleuri, 20g of codonopsis pilosula, 10g of astragalus membranaceus, 12g of dried orange peel, 10g of poria cocos, 30g of coix seeds, 15g of Chinese sage herb, 20g of thunberg fritillary bulb, 6g of ligusticum wallichii, 30g of sculellaria barbata, 3g of cinnamon and 20g of bighead atractylodes rhizome, soaking in water, adding water to submerge the medicine surface for 2cm, and soaking for 20min, wherein the water temperature is 50 ℃;
s2, decocting the soaked medicinal materials, keeping the medicinal materials in a slightly boiling state with strong fire when the medicinal materials are not boiled and with slow fire after the medicinal materials are boiled, boiling for 20min, and collecting first decoction liquid; the best utensil for decocting the medicines is a marmite, a ceramic pot or a stainless steel pot;
s3, adding the same water amount as the first decoction into the traditional Chinese medicine, carrying out second decoction under the same condition as the first decoction, and collecting liquid medicine of the second decoction;
and S4, combining the first decoction and the second decoction to obtain the Chinese herbal medicine.
Example 2
A preparation method of a traditional Chinese medicine composition for treating pulmonary nodules comprises the following steps:
s1, weighing 12g of radix bupleuri, 10g of codonopsis pilosula, 20g of astragalus membranaceus, 6g of dried orange peel, 20g of poria cocos, 15g of coix seeds, 30g of Chinese sage herb, 10g of thunberg fritillary bulb, 12g of ligusticum wallichii, 15g of sculellaria barbata, 6g of cinnamon and 10g of bighead atractylodes rhizome, soaking in water, adding water to submerge the medicine surface for 3cm, and soaking for 40min, wherein the water temperature is 25 ℃;
s2, decocting the soaked medicinal materials, keeping the medicinal materials in a slightly boiling state with strong fire when the medicinal materials are not boiled and with slow fire after the medicinal materials are boiled, boiling for 30min, and collecting first decoction liquid; the best utensil for decocting the medicines is a marmite, a ceramic pot or a stainless steel pot;
s3, adding the same water amount as the first decoction into the traditional Chinese medicine, carrying out second decoction under the same condition as the first decoction, and collecting liquid medicine of the second decoction;
and S4, combining the first decoction and the second decoction to obtain the Chinese herbal medicine.
Example 3
A preparation method of a traditional Chinese medicine composition for treating pulmonary nodules comprises the following steps:
s1, weighing 10g of radix bupleuri, 20g of codonopsis pilosula, 20g of astragalus membranaceus, 10g of dried orange peel, 10g of poria cocos, 20g of coix seeds, 20g of Chinese sage herb, 20g of thunberg fritillary bulb, 10g of ligusticum wallichii, 15g of sculellaria barbata, 5g of cinnamon and 10g of bighead atractylodes rhizome, soaking in water, adding water to submerge the medicine surface for 2cm, and soaking for 30min, wherein the water temperature is 40 ℃;
s2, decocting the soaked medicinal materials, keeping the medicinal materials in a slightly boiling state with strong fire when the medicinal materials are not boiled and with slow fire after the medicinal materials are boiled, boiling for 25min, and collecting first decoction liquid; the best utensil for decocting the medicines is a marmite, a ceramic pot or a stainless steel pot;
s3, adding the same water amount as the first decoction into the traditional Chinese medicine, carrying out second decoction under the same condition as the first decoction, and collecting liquid medicine of the second decoction;
and S4, combining the first decoction and the second decoction to obtain the Chinese herbal medicine.
Example 4
A preparation method of a traditional Chinese medicine composition for treating pulmonary nodules comprises the following steps:
s1, weighing 10g of radix bupleuri, 20g of codonopsis pilosula, 20g of astragalus membranaceus, 10g of dried orange peel, 10g of poria cocos, 20g of coix seeds, 20g of Chinese sage herb, 20g of thunberg fritillary bulb, 10g of ligusticum wallichii, 15g of sculellaria barbata, 5g of cinnamon and 10g of bighead atractylodes rhizome, soaking in water, adding water to submerge the medicine surface for 3cm, and soaking for 30min, wherein the water temperature is 30 ℃;
s2, decocting the soaked medicinal materials, keeping the medicinal materials in a slightly boiling state with strong fire when the medicinal materials are not boiled and with slow fire after the medicinal materials are boiled, boiling for 20min, and collecting first decoction liquid; the best utensil for decocting the medicines is a marmite, a ceramic pot or a stainless steel pot;
s3, adding the same water amount as the first decoction into the traditional Chinese medicine, carrying out second decoction under the same condition as the first decoction, and collecting liquid medicine of the second decoction;
and S4, combining the first decoction and the second decoction to obtain the Chinese herbal medicine.
Clinical cases
Case 1:
suzhou, woman, 69 years old, and diagnosed on day 26 of 09 months and 2019 with "3 weeks of findings on the lower left pulmonary nodules by physical examination". The diagnosis shows that cough, expectoration, little sputum, white sputum, plain and easy sweating and insomnia can occur. There are thyroid nodules and mammary lobular hyperplasia. CT of chest shows: left lower lung nodule, about 7 mm. The four diagnostic methods are combined to differentiate the syndrome of lung-spleen qi deficiency and phlegm-stasis accumulation, so it is indicated for tonifying qi, strengthening spleen, activating blood and resolving stasis.
The method of example 3 is adopted to prepare the traditional Chinese medicine decoction, 1 dose of the traditional Chinese medicine is taken for 2 times, 1 hour before meal, and less oily, spicy and hot food is taken during the period of taking the traditional Chinese medicine.
The doctor makes a return visit 10 months and 10 days in 2019, and the patient has relieved expectoration after complaint of the medicine compared with the former, the effect is not better, and the original prescription is advanced. A high-resolution chest CT review on 12, 4 and 2019 indicated that the lower lobe nodules of the left lung were significantly reduced and dissipated.
Case 2:
some, female, 52 years old, first diagnosis in 2019, 3 months and 8 months after finding pulmonary nodules by physical examination. The patient has short intermittent cough without phlegm and has no acute cough, and the pulmonary nodules are easy to be anxious, have poor sleep and have hypodynamia after physical examination. CT of chest shows: left lung inferior lobe nodule, about 7mm, edge blur. The four diagnostic methods are combined, and the syndrome differentiation is that the lung and spleen are qi deficiency and phlegm stasis is internally accumulated, so that the treatment is suitable for tonifying qi and spleen, and activating blood and dissolving stasis; meanwhile, the mind is smooth.
The method of example 4 is adopted to prepare the traditional Chinese medicine decoction, 1 dose of the traditional Chinese medicine is taken for 2 times, 1 hour before meal, and less oily, spicy and hot food is taken during the period of taking the traditional Chinese medicine.
After the patient takes the medicine for 1 week, the sleep quality is improved, the fatigue is improved, and the anxiety is relieved. The disappearance of left lung inferior lobe nodules is shown by rechecking chest high-resolution CT on 2019, 5 and 11 days after 2 months of administration.
The embodiments of the present invention are preferred embodiments of the present invention, and the scope of the present invention is not limited by these embodiments, so: all equivalent changes made according to the structure, shape and principle of the invention are covered by the protection scope of the invention.

Claims (5)

1. A traditional Chinese medicine composition for treating pulmonary nodules is characterized in that: the paint comprises the following components in parts by weight: 6-12 parts of radix bupleuri, 10-20 parts of codonopsis pilosula, 10-20 parts of astragalus membranaceus, 6-12 parts of pericarpium citri reticulatae, 10-20 parts of poria cocos, 15-30 parts of coix seeds, 15-30 parts of Chinese sage herb, 10-20 parts of thunberg fritillary bulb, 6-12 parts of ligusticum wallichii, 15-30 parts of sculellaria barbata, 3-6 parts of cinnamon and 10-20 parts of bighead atractylodes rhizome.
2. The traditional Chinese medicine composition for treating pulmonary nodules according to claim 1, wherein: the paint comprises the following components in parts by weight:
10 parts of radix bupleuri, 20 parts of codonopsis pilosula, 20 parts of astragalus membranaceus, 10 parts of pericarpium citri reticulatae, 10 parts of poria cocos, 20 parts of coix seeds, 20 parts of Chinese sage herb, 20 parts of thunberg fritillary bulb, 10 parts of ligusticum wallichii, 15 parts of sculellaria barbata, 5 parts of cinnamon and 10 parts of bighead atractylodes rhizome.
3. The traditional Chinese medicine composition for treating pulmonary nodules according to claim 1, wherein: the paint comprises the following components in parts by weight:
10 parts of radix bupleuri, 20 parts of codonopsis pilosula, 20 parts of astragalus membranaceus, 10 parts of pericarpium citri reticulatae, 10 parts of poria cocos, 20 parts of coix seeds, 20 parts of Chinese sage herb, 20 parts of thunberg fritillary bulb, 10 parts of ligusticum wallichii, 15 parts of sculellaria barbata, 5 parts of cinnamon and 10 parts of bighead atractylodes rhizome.
4. A method for preparing a Chinese medicinal composition for treating pulmonary nodules as claimed in any of claims 1-3, wherein the method comprises the steps of: the method comprises the following steps:
s1, weighing specified amounts of radix bupleuri, codonopsis pilosula, astragalus membranaceus, pericarpium citri reticulatae, poria cocos, coix seeds, Chinese sage herb, thunberg fritillary bulb, ligusticum wallichii, barbed skullcap herb, cinnamon and bighead atractylodes rhizome, soaking in water, adding water to submerge the medicine surface for 2-3cm, and soaking for 20-40 min;
s2, decocting the soaked medicinal materials, boiling for 20-30min, and collecting a first decoction;
s3, adding the same water amount as the first decoction into the traditional Chinese medicine, carrying out second decoction under the same condition as the first decoction, and collecting liquid medicine of the second decoction;
and S4, combining the first decoction and the second decoction to obtain the Chinese herbal medicine.
5. The method for preparing a Chinese medicinal composition for treating pulmonary nodules as claimed in claim 4, wherein: in step S1, the temperature of the water for soaking the traditional Chinese medicine is 25-50 ℃.
CN202110532940.5A 2021-05-17 2021-05-17 Traditional Chinese medicine composition for treating pulmonary nodules and preparation method thereof Pending CN113117030A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115814019A (en) * 2022-12-12 2023-03-21 湖南中医药大学 Traditional Chinese medicine composition for treating pulmonary nodules and preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
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CN111053862A (en) * 2018-10-17 2020-04-24 徐定清 Traditional Chinese medicine pill for tonifying qi, invigorating spleen and eliminating stagnation
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