CN108904669A - A kind of Chinese materia medica preparation for treating hyperlipidemia - Google Patents
A kind of Chinese materia medica preparation for treating hyperlipidemia Download PDFInfo
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- CN108904669A CN108904669A CN201811101096.5A CN201811101096A CN108904669A CN 108904669 A CN108904669 A CN 108904669A CN 201811101096 A CN201811101096 A CN 201811101096A CN 108904669 A CN108904669 A CN 108904669A
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- materia medica
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- 238000002360 preparation method Methods 0.000 title claims abstract description 26
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- Hematology (AREA)
- Obesity (AREA)
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Abstract
The invention discloses a kind of Chinese materia medica preparation for treating hyperlipidemia, being in parts by weight includes following traditional Chinese medicine ingredients：Rhizoma Chuanxiong 11g, leech 16g, Poria cocos 13g, Snakegourd Fruit 16g, tuber of pinellia 13g, rhizoma alismatis 11g, hawthorn 18g, rhizoma cyperi 13g.The preparation and application of the traditional chinese medicine composition of the invention：First by medicinal material with cold water soak 2 hours, the water of immersion is advisable with flooding 3 ~ 5cm of powder, and medicine is placed on fire, (i.e. high fire) is endured out with high heat, it uses mild fire (small fire) after boiling instead and keeps slight boiling condition, decoct 50 minutes for the first time, medical fluid is poured out, second of decoction is added just to flood the hot water of dregs of a decoction 2-3cm, it decocts 30 minutes, medical fluid is poured out, 2 medical fluids are mixed into 1 dose, daily 1 dose, divides 3 times and warmly take.
Description
Technical field
The invention belongs to Chinese medicine compositions, specifically, being to be related to a kind of Chinese materia medica preparation for hyperlipemia therapeutic.
Background technique
Hyperlipidemia（Hyperlipidemia, HLP）With cholesterol and triglyceride levels it is excessively high or with serum it is highly dense
Lipoprotein cholesterol level is too low is characterized for degree, is the significant risk for causing atherosclerosis and ischemic angiocardiopathy and cerebrovascular disease
One of factor.The morbidity of a large amount of clinical and epidemiological study discovery HLP and coronary heart disease, hypertension and cerebral apoplexy has directly
Relationship, therefore develop the project that effective blood lipid-lowering medicine has become global concern.There are many chemically synthesized lipid-lowering medicines, but mesh
All there is knock-on of being discontinued, hepatorenal damage, the side effects such as rhabdomyolysis for preceding majority lipid-loweringing Western medicine, and most synthetic drugs are bases
In the mechanism of action of single target spot, in many-sided lipid-loweringing and in terms of improving symptom, there are biggish limitations.
Hyperlipidemia is commonly encountered diseases of internal department, and disease incidence is higher.Hyperlipidemia category Chinese medicine " the turbid blood stasis of phlegm " scope, this mostly due to
Spleen undermines kidney, and causes kidney qi virtual loss or stagnation of phlegm converting into fire, injures its negative, deficiency of liver-yin and kidney-yin, or because phlegm causes the stasis of blood, and causes phlegm and blood stasis.This
A little pathological changes can be regarded as the dysfunction of the spleen in transport, the differentiation of this interpretation of the cause, onset and process of an illness of phlegm resistance.So spleen is that influence rouge is turbid at change
Key, the dysfunction of the spleen in transportation and transformation of spleen, the turbid cohesion injection blood vessels of phlegm are the key that the hyperlipidemia interpretation of the cause, onset and process of an illness；Spleen deficiency loses fortune, and deficiency of kidney-essence is to lead
Phlegm-blood stasis is caused to be formed, so that form the inherent cause of disease of hyperlipidemia；Addiction delicious food sorghum savoury is that metaplasia phlegm is turbid, facilitates hyperlipidemia
External conditions；Phlegm and blood stasis deposits blood mansion, and it is that hyperlipidemia development necessarily turns for other diseases such as cardiovascular and cerebrovascular that sering, which loses honor,
Return.Chinese traditional treatment should be dropped with strengthening the spleen and replenishing qi, eliminating the phlegm based on turbid, activating microcirculation and removing stasis medicinal.Therefore how to be ground according to traditional Chinese medicine and pharmacy curative mechanism
Producing a kind of Chinese medicine for treating hyperlipidemia is urgent problem.
The present invention is used to treat the Chinese medicine preparation of hyperlipidemia, for the hyperlipidemia cause of disease interpretation of the cause, onset and process of an illness, pay attention to from liver-kidney tonifying,
Fortune spleen resolving sputum, double three aspects of tune of qi and blood discuss and are controlled, and the turbid dissolving stasis of emphasis, lively atmosphere lead to blood.Hyperlipemia pathogenic factor is mostly
Eating and drinking without temperance, few labor is excessive, and overfeeding delicious food savoury leads to visceral dysfunction, causes turbid rouge retention caused by blood vessels.
Summary of the invention
The purpose of the present invention is to provide the Chinese materia medica preparation for the treatment of hyperlipidemia, overcome the deficiencies in the prior art avoids controlling
It treats hyperlipidemia and takes Western medicine side effect caused by patient body, there is significant curative effect, preparation method letter to hyperlipidemia
Just, safe and reliable.
In order to achieve the above-mentioned object of the invention, the raw material composition and its weight proportion of the effective ingredient is made in the present invention
For：Rhizoma Chuanxiong 11g, leech 16g, Poria cocos 13g, Snakegourd Fruit 16g, tuber of pinellia 13g, rhizoma alismatis 11g, hawthorn 18g, rhizoma cyperi 13g.
The preparation and application of the traditional chinese medicine composition of the invention：First by medicinal material with cold water soak 2 hours, the water of immersion with
Flooding 3 ~ 5cm of powder is advisable, and medicine is placed on fire, and (i.e. high fire) is endured out with high heat, uses mild fire (small fire) after boiling instead and keeps micro-
Boiling state decocts 50 minutes for the first time, medical fluid is poured out, and second of decoction is added just to flood the hot water of dregs of a decoction 2-3cm, decocts
30 minutes, medical fluid is poured out, 2 medical fluids are mixed into 1 dose, daily 1 dose, divides 3 times and warmly takes.
Invention selects natural drug, for the hyperlipidemia cause of disease interpretation of the cause, onset and process of an illness, each taste for treating the Chinese materia medica preparation of hyperlipidemia
Medicinal material respectively has its effect, coordinates mutually, reuses leech, Rhizoma Chuanxiong dissipating blood stasis with potent drugs, turbid with the stasis of blood for washing away sering；Snakegourd Fruit, the tuber of pinellia are played altogether to disappear
The function of turbidity phlegm；" phlegm coming from spleen ", therefore with Poria cocos benefit spleen resolving sputum；Rhizoma alismatis, which can seep water to rush down, wet and wet removes phlegm；Rhizoma cyperi is blood
In gas medicine, can pass through vim and vigour, enhance stasis eliminatings resolving sputum power；Hawthorn then has the benefits of scattered stasis, eliminate indigestion and phlegm；All medicines are played altogether
The function of phlegm reduction of blood circulation promoting, function of invigorating circulation and reducing blood fat.
Specific embodiment
Embodiment 1：A kind of Chinese materia medica preparation for treating hyperlipidemia includes following traditional Chinese medicine ingredients in parts by weight：Rhizoma Chuanxiong
11g, leech 16g, Poria cocos 13g, Snakegourd Fruit 16g, tuber of pinellia 13g, rhizoma alismatis 11g, hawthorn 18g, rhizoma cyperi 13g.
Embodiment 2：If patient's insufficiency of both the spleen and the kindey, Morinda officinalis 11g, thizoma curculiginis 13g, Herba Epimedii 11g are added in said components.
Embodiment 3：If patient's deficiency of liver-yin and kidney-yin, Rhizoma Atractylodis Macrocephalae 13g, fructus lycii 13g, rhizoma polygonati 13g are added in said components.
Embodiment 4：It is checked if patient's phlegm is turbid, arisaema cum bile 13g, caulis bambusae in taenian 13g is added in said components.
Embodiment 5：If patient's stagnation of the circulation of vital energy network stasis of blood, Rhizoma Chuanxiong 13g, rhizoma corydalis 11g, Radix Salviae Miltiorrhizae 13g, Radix Notoginseng are added in said components
11g。
Embodiment 6：If patient's hyperactivity of yang due to yin deficiency, Rhizoma Gastrodiae 11g, oyster 16g are added in said components.
First by medicinal material with cold water soak 2 hours, the water of immersion is advisable with flooding 3 ~ 5cm of powder, and medicine is placed on fire, is used
Intense fire (i.e. high fire) is endured out, and is used mild fire (small fire) after boiling instead and is kept slight boiling condition, decocts 50 minutes for the first time, medical fluid is fallen
Out, addition being decocted just to flood the hot water of dregs of a decoction 2-3cm second, decocting 30 minutes, medical fluid is poured out, 2 medical fluids are mixed
It is 1 dose, daily 1 dose, divides 3 times and warmly take.
The clinical treatment effect of the Chinese materia medica preparation of the present invention for hyperlipemia nursing is illustrated below by way of practical example
Fruit.
1, clinical data
Clinical observation hyperlipemia 52, male 29, female 23, the age：38-65 years old, average 51 ± 10, referring to China doctor
Learn angiocardiology branch《2007 Blood Lipid Abnormality in Chinese Adults guideline of prevention and treatment》The diagnostic criteria of formulation and《New Chinese medicine is controlled
Treat the guideline of clinical investigations of hyperlipidemia》" qi deficiency and phlegm stagnation syndrome syndrome of blood stasis " standard is examined in TCM syndrome diagnostic criteria
It is disconnected.
2, criterion of therapeutical effect
It cures：Erythema all subsides, papulopustule is all calmed down, pachydermatosis whole or is substantially eliminated, is no longer recurred；
Effectively：The whole recession of erythema, papule, warts calms down substantially, pachydermatosis is substantially or partially eliminated, occasionally has recurrence；
In vain：Erythema is without subsiding or increasing, and papule useless fellow is without calming down, and pachydermatosis is without elimination.
3, treatment results
Therapeutic effect：In the clinical observation case, the 3-5 course for the treatment of of taking medicine is fully recovered 95, follow-up no relapse, and effective 27, nothing
Effect 9, total effective rate 93.13%, middle adverse drug reaction（ADR）Evaluation, adverse reaction and toxic side effect do not occur.
Typical case：
Sun, female, 67 years old, when hospital admission, main suit：Dizzy recurrent exerbation 4 years, symptoms include：Alliteration is dizzy, and brothers are powerless,
Soreness and weakness of waist and knees, failure of memory, chest distress and palpitation symptoms, lassitude, diet is depressed, constipation, insomnia and dreamful sleep, red tongue body, Bian You
Ecchymosis, greasy and thin fur, wiry and rolling pulse, blood pressure：155/100mmHg, lipid examination：Total cholesterol（TC）7.8mmol/L, triacylglycerol
（TG）8.78mmol/L high-density lipoprotein（HDL-C）0.28mmol/L, low-density lipoprotein（LDL-C）7.71mmol/L distinguishing
Card：The deficiency of liver-yin and kidney-yin, phlegm, which becomes silted up, hinders network, rules for the treatment of liver-kidney tonifying, and stasis eliminatings resolving sputum takes 10 doses of inventive formulation, daily 1 dose, is decocted in water for oral dose,
Order is advised to be adhered to being used on behalf of the tea with after a small amount of lotus leaf, chrysanthemum, honeysuckle decocting daily, and diet is light, appropriate exercise, keeps pleasant
Mood, avoid spirit from being chronically at tense situation, into cross half a year medical treatment, patient symptom disappear, full of vitality, pink tongue,
Tongue fur is thin white, and arteries and veins is thin, and check blood lipid indices belong to normal range (NR).
Claims (7)
1. a kind of Chinese materia medica preparation for treating hyperlipidemia, it is characterised in that：The Chinese materia medica preparation includes following Chinese medicine in parts by weight
Ingredient：Rhizoma Chuanxiong 11g, leech 16g, Poria cocos 13g, Snakegourd Fruit 16g, tuber of pinellia 13g, rhizoma alismatis 11g, hawthorn 18g, rhizoma cyperi 13g.
2. a kind of Chinese materia medica preparation for treating hyperlipidemia as described in claim 1, it is characterised in that：The Chinese materia medica preparation further includes
Morinda officinalis 11g, thizoma curculiginis 13g, Herba Epimedii 11g.
3. a kind of Chinese materia medica preparation for treating hyperlipidemia as described in claim 1, it is characterised in that：The Chinese materia medica preparation further includes
Rhizoma Atractylodis Macrocephalae 13g, fructus lycii 13g, rhizoma polygonati 13g.
4. a kind of Chinese materia medica preparation for treating hyperlipidemia as described in claim 1, it is characterised in that：The Chinese materia medica preparation further includes
Arisaema cum bile 13g, caulis bambusae in taenian 13g.
5. a kind of Chinese materia medica preparation for treating hyperlipidemia as described in claim 1, it is characterised in that：The Chinese materia medica preparation further includes
Rhizoma Chuanxiong 13g, rhizoma corydalis 11g, Radix Salviae Miltiorrhizae 13g, Radix Notoginseng 11g.
6. a kind of Chinese materia medica preparation for treating hyperlipidemia as described in claim 1, it is characterised in that：The Chinese materia medica preparation further includes
Rhizoma Gastrodiae 11g, oyster 16g.
7. a kind of preparation method for the Chinese materia medica preparation for treating hyperlipidemia as described in claim 1, it is characterised in that：First by medicine
Material was with cold water soak 2 hours, and the water of immersion is advisable with flooding 3 ~ 5cm of powder, and medicine is placed on fire, and (i.e. high fire) is endured with high heat
It opens, uses mild fire (small fire) holding slight boiling condition after boiling instead, decoct 50 minutes for the first time, medical fluid is poured out, second of decoction adds
Enter just to flood the hot water of dregs of a decoction 2-3cm, decoct 30 minutes, medical fluid is poured out, 2 medical fluids are mixed into 1 dose, daily 1 dose, are divided
It warmly takes for 3 times.
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