CN1130873A - 用氮杂螺烷治疗hiv的方法 - Google Patents

用氮杂螺烷治疗hiv的方法 Download PDF

Info

Publication number
CN1130873A
CN1130873A CN94193382A CN94193382A CN1130873A CN 1130873 A CN1130873 A CN 1130873A CN 94193382 A CN94193382 A CN 94193382A CN 94193382 A CN94193382 A CN 94193382A CN 1130873 A CN1130873 A CN 1130873A
Authority
CN
China
Prior art keywords
chemical compound
hiv
formula
solvate
hydrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN94193382A
Other languages
English (en)
Chinese (zh)
Inventor
A·M·贝杰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of CN1130873A publication Critical patent/CN1130873A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN94193382A 1993-07-23 1994-07-22 用氮杂螺烷治疗hiv的方法 Pending CN1130873A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9315351.8 1993-07-23
GB939315351A GB9315351D0 (en) 1993-07-23 1993-07-23 Methods

Publications (1)

Publication Number Publication Date
CN1130873A true CN1130873A (zh) 1996-09-11

Family

ID=10739366

Family Applications (1)

Application Number Title Priority Date Filing Date
CN94193382A Pending CN1130873A (zh) 1993-07-23 1994-07-22 用氮杂螺烷治疗hiv的方法

Country Status (9)

Country Link
EP (1) EP0717622A4 (fr)
JP (1) JPH09500646A (fr)
CN (1) CN1130873A (fr)
AU (1) AU7514094A (fr)
CA (1) CA2167843A1 (fr)
GB (1) GB9315351D0 (fr)
NZ (1) NZ271496A (fr)
WO (1) WO1995003049A1 (fr)
ZA (1) ZA945417B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9315340D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods
GB9315306D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods
BR9601909A (pt) * 1995-07-13 1999-10-13 Smithkline Beecham Corp N,n-dietil-8,8-dipropil-2-azaspiro(4,5)decano-2-propan amina dimaleato
WO1997044030A1 (fr) * 1996-05-17 1997-11-27 Anormed Inc. Utilisation d'azaspirane substitue dans le traitement de l'asthme

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963557A (en) * 1987-09-28 1990-10-16 Smithkline Beecham Corporation Immunomodulatory azaspiranes
ZA921120B (en) * 1991-02-19 1993-01-27 Smithkline Beecham Corp Cytokine inhibitors
GB9201803D0 (en) * 1992-01-28 1992-03-11 Smithkline Beecham Corp Methods
GB9201804D0 (en) * 1992-01-28 1992-03-11 Smithkline Beecham Corp Methods
GB9315340D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods
GB9315306D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods
GB9315341D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods

Also Published As

Publication number Publication date
WO1995003049A1 (fr) 1995-02-02
EP0717622A1 (fr) 1996-06-26
NZ271496A (en) 1999-06-29
ZA945417B (en) 1995-05-10
JPH09500646A (ja) 1997-01-21
AU7514094A (en) 1995-02-20
GB9315351D0 (en) 1993-09-08
EP0717622A4 (fr) 1998-09-09
CA2167843A1 (fr) 1995-02-02

Similar Documents

Publication Publication Date Title
US6051596A (en) Immunosuppressive compositions
JPH05170771A (ja) 成人t−細胞白血病/リンパ腫の治療用医薬組成物
JP2904827B2 (ja) 不安および不安抑うつ障害の処置に有用な医薬組成物の調製へのトリフルオロメチルフェニルテトラヒドロピリジンの使用
JPS63310819A (ja) 抗レトロウイルス活性をもつ糖タンパク処理抑制剤
JPH02243666A (ja) ニューモシスティス・カリニ肺炎などの疾病の治療法および予防法そしてこれらの方法に用いる化合物および処方物
CN1130873A (zh) 用氮杂螺烷治疗hiv的方法
CN1130871A (zh) 用取代的氮杂螺烷抑制人体免疫缺陷病毒的复制的方法
CN1130870A (zh) 用取代的氮杂螺环烃类化合物抑制人免疫缺陷病毒产生的方法
US6670351B1 (en) Method for ameliorating muscle weakness/wasting in a patient infected with human immunodeficiency virus-type 1
US5482959A (en) Method for delaying aids in an HIV infected individual by administration of substituted azaspirane compounds
WO1994005300A1 (fr) Utilisation de la rapamycine dans le traitement du sida
EP0624089A1 (fr) Procedes
JP2007297412A (ja) ヒト・ヘルペスウイルス−8の治療に対するペンシクロビルの使用
CN1175212A (zh) 氨基嘌呤抗病毒剂在治疗和预防潜伏性疱疹病毒感染中的用途
AU684384B2 (en) Method of treating opportunistic infections with azaspiranes
US5786376A (en) Methods of treating opportunistic infections with azaspiranes
WO1993014771A1 (fr) Composes macrocycliques servant au traitement prophylactique du sida
RU2005475C1 (ru) Противовирусное средство
US6090799A (en) Method for ameliorating muscle weakness/wasting in a patient infected with human immunodeficiency virus-type 1
US20070254029A1 (en) Method for ameliorating muscle weakness/wasting in a patient infected with human immunodeficiency virus-type 1
AU710542B2 (en) Use of substituted azaspirane in the treatment of asthma
JPH09500647A (ja) 置換アザスピランによるヒト免疫不全ウイルス産生の阻害法
WO1993008801A1 (fr) Prevention de l'agranulocytose induite par des medicaments avec piegeurs de radicaux libres
JPH08119860A (ja) 脂肪肝の予防または治療剤
UA72468C2 (en) Use of sodium chloride for preventing gastrointestinal side effects upon administration of camptothecin derivatives

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication