CN113080450A - Health food for inhibiting and killing helicobacter pylori and preparation method thereof - Google Patents
Health food for inhibiting and killing helicobacter pylori and preparation method thereof Download PDFInfo
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- CN113080450A CN113080450A CN202110394832.6A CN202110394832A CN113080450A CN 113080450 A CN113080450 A CN 113080450A CN 202110394832 A CN202110394832 A CN 202110394832A CN 113080450 A CN113080450 A CN 113080450A
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- 241000590002 Helicobacter pylori Species 0.000 title claims abstract description 26
- 229940037467 helicobacter pylori Drugs 0.000 title claims abstract description 26
- 235000013402 health food Nutrition 0.000 title claims abstract description 22
- 230000002401 inhibitory effect Effects 0.000 title claims abstract description 20
- 230000002147 killing effect Effects 0.000 title claims abstract description 20
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- 239000002994 raw material Substances 0.000 claims abstract description 14
- 239000003755 preservative agent Substances 0.000 claims abstract description 13
- 230000002335 preservative effect Effects 0.000 claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 13
- 235000007866 Chamaemelum nobile Nutrition 0.000 claims abstract description 11
- 244000042664 Matricaria chamomilla Species 0.000 claims abstract description 11
- 235000007232 Matricaria chamomilla Nutrition 0.000 claims abstract description 11
- 241000220317 Rosa Species 0.000 claims abstract description 11
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 claims abstract description 11
- 239000000945 filler Substances 0.000 claims abstract description 11
- 239000000843 powder Substances 0.000 claims description 18
- 241000628997 Flos Species 0.000 claims description 12
- 239000000284 extract Substances 0.000 claims description 12
- 238000000227 grinding Methods 0.000 claims description 12
- 238000002156 mixing Methods 0.000 claims description 12
- 238000004806 packaging method and process Methods 0.000 claims description 12
- 238000007873 sieving Methods 0.000 claims description 12
- 238000005303 weighing Methods 0.000 claims description 12
- 241000245665 Taraxacum Species 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 9
- 239000004067 bulking agent Substances 0.000 claims description 8
- 244000269722 Thea sinensis Species 0.000 claims description 6
- 238000007605 air drying Methods 0.000 claims description 6
- 230000002421 anti-septic effect Effects 0.000 claims description 6
- 239000004599 antimicrobial Substances 0.000 claims description 6
- 238000004140 cleaning Methods 0.000 claims description 6
- 238000004821 distillation Methods 0.000 claims description 6
- 239000012153 distilled water Substances 0.000 claims description 6
- 238000000605 extraction Methods 0.000 claims description 6
- 238000001914 filtration Methods 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 238000000643 oven drying Methods 0.000 claims description 6
- 238000010298 pulverizing process Methods 0.000 claims description 6
- 229920002774 Maltodextrin Polymers 0.000 claims description 2
- 239000005913 Maltodextrin Substances 0.000 claims description 2
- 239000005452 food preservative Substances 0.000 claims description 2
- 235000019249 food preservative Nutrition 0.000 claims description 2
- 229940035034 maltodextrin Drugs 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 10
- 235000013305 food Nutrition 0.000 abstract description 5
- 239000003814 drug Substances 0.000 abstract description 4
- 231100000331 toxic Toxicity 0.000 abstract description 3
- 230000002588 toxic effect Effects 0.000 abstract description 3
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 208000005718 Stomach Neoplasms Diseases 0.000 description 4
- 239000003242 anti bacterial agent Substances 0.000 description 4
- 229940088710 antibiotic agent Drugs 0.000 description 4
- 208000011580 syndromic disease Diseases 0.000 description 4
- 206010059866 Drug resistance Diseases 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000002829 reductive effect Effects 0.000 description 3
- 239000003674 animal food additive Substances 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- 208000008469 Peptic Ulcer Diseases 0.000 description 1
- 108010046334 Urease Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000001574 biopsy Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 210000004211 gastric acid Anatomy 0.000 description 1
- 206010017758 gastric cancer Diseases 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 238000002575 gastroscopy Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000007490 hematoxylin and eosin (H&E) staining Methods 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 208000011906 peptic ulcer disease Diseases 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 201000011549 stomach cancer Diseases 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/34—Tea substitutes, e.g. matè; Extracts or infusions thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
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- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the technical field of health-care food, and discloses health-care food for inhibiting and killing helicobacter pylori and a preparation method thereof, wherein the health-care food comprises the following raw materials in parts by weight: 40-60 parts of chamomile, 30-50 parts of dandelion, 5-20 parts of rose, 1-5 parts of preservative and 1-20 parts of filler. The health food for inhibiting and killing the helicobacter pylori, which is prepared by the invention, can effectively inhibit and kill the helicobacter pylori, has simple preparation process, low cost and convenient eating, can be drunk after being mixed with water or directly, has no toxic or side effect on the traditional Chinese medicine raw materials, and is suitable for different people to take.
Description
Technical Field
The invention relates to the technical field of health-care food, in particular to health-care food for inhibiting and killing helicobacter pylori and a preparation method thereof.
Background
Helicobacter pylori is classified as one of 12 "superbacteria" in urgent need of novel antibiotics by the world health organization due to its drug resistance. The data show that 100 million new gastric cancers are developed every year in China, 50 new gastric cancers are developed in China, and nearly 20 ten thousand gastric cancers take lives. As one of the 'fierce' causing gastric cancer, more than 50% of people in the world are infected by helicobacter pylori, and the infection rate of Chinese people is up to 60%. The prevalence, severity of the disease, severity of drug resistance of H.pylori infection have become common problems that compromise human health. Helicobacter pylori is very powerful. The human stomach is the only natural host for H.pylori, which cannot be killed by strong gastric acid. The currently more effective treatment is triple or quadruple therapy with two antibiotics. However, long-term use of antibiotics can cause the strains to generate drug resistance, affect the treatment effect, reduce the radical treatment rate, even have side effects of destroying the balance of gastrointestinal flora, disturbing metabolism and immunity and the like, and increase the occurrence risk of other diseases.
Disclosure of Invention
Aiming at the problems in the background, the invention provides the health food for inhibiting and killing the helicobacter pylori and the preparation method thereof, and the health food has simple preparation and good effect.
A health food for inhibiting and killing helicobacter pylori comprises the following raw materials by weight: 40-60 parts of chamomile, 30-50 parts of dandelion, 5-20 parts of rose, 1-5 parts of preservative and 1-20 parts of filler.
Preferably, the feed additive consists of the following raw materials in parts by weight: 45 parts of chamomile, 35 parts of dandelion, 10 parts of rose, 1 part of preservative and 9 parts of filler.
Preferably, the feed additive consists of the following raw materials in parts by weight: 50 parts of chamomile, 40 parts of dandelion, 5 parts of rose, 1 part of preservative and 4 parts of filler.
Preferably, the preservative is a food preservative, and the bulking agent is maltodextrin.
Preferably, the preparation method comprises the following steps:
(1) weighing and crushing: cleaning flos Matricariae Chamomillae, herba Taraxaci and flos Rosae Rugosae, air drying, weighing according to proportion, pulverizing respectively, and mixing thoroughly.
(2) Distillation and extraction: adding distilled water into the above mixture, decocting for 1-3 hr, filtering, removing residue, concentrating the clear liquid, and oven drying to obtain extract.
(3) Grinding and sieving: grinding the above extracts, antiseptic and bulking agent into powder, respectively, mixing, and sieving to obtain powder;
(4) granulating and packaging: granulating the above powders with a granulator, and packaging.
Preferably, the eating method of the health food is tea making or direct eating.
The invention has the beneficial effects that:
the health food for inhibiting and killing the helicobacter pylori, which is prepared by the invention, can effectively inhibit and kill the helicobacter pylori, has simple preparation process, low cost and convenient eating, can be drunk after being mixed with water or directly, has no toxic or side effect on the traditional Chinese medicine raw materials, and is suitable for different people to take.
Detailed Description
Embodiments of the present invention will be described in detail below with reference to examples, but those skilled in the art will understand that the following examples are only for illustrating the present invention and are not to be construed as limiting the scope of the present invention, and that those not specifically noted in the examples are performed according to the techniques or conditions described in the literature in the art or according to the product specification.
The first embodiment is as follows:
a health food for inhibiting and killing helicobacter pylori comprises the following raw materials by weight: 45 parts of chamomile, 35 parts of dandelion, 10 parts of rose, 1 part of preservative and 9 parts of filler.
The preparation method comprises the following steps:
(1) weighing and crushing: cleaning flos Matricariae Chamomillae, herba Taraxaci and flos Rosae Rugosae, air drying, weighing according to proportion, pulverizing respectively, and mixing thoroughly.
(2) Distillation and extraction: adding distilled water into the above mixture, decocting for 2 hr, filtering, removing residue, concentrating the clear liquid, and oven drying to obtain extract.
(3) Grinding and sieving: grinding the above extracts, antiseptic and bulking agent into powder, respectively, mixing, and sieving to obtain powder;
(4) granulating and packaging: granulating the above powders with a granulator, and packaging.
The eating method comprises the following steps: the tea is drunk after being mixed with water or directly eaten twice a day.
Example two:
a health food for inhibiting and killing helicobacter pylori comprises the following raw materials by weight: 50 parts of chamomile, 40 parts of dandelion, 5 parts of rose, 1 part of preservative and 4 parts of filler.
The preparation method comprises the following steps:
(1) weighing and crushing: cleaning flos Matricariae Chamomillae, herba Taraxaci and flos Rosae Rugosae, air drying, weighing according to proportion, pulverizing respectively, and mixing thoroughly.
(2) Distillation and extraction: adding distilled water into the above mixture, decocting for 1.5 hr, filtering, removing residue, concentrating the clear liquid, and oven drying to obtain extract.
(3) Grinding and sieving: grinding the above extracts, antiseptic and bulking agent into powder, respectively, mixing, and sieving to obtain powder;
(4) granulating and packaging: granulating the above powders with a granulator, and packaging.
The eating method comprises the following steps: the tea is drunk after being mixed with water or directly eaten twice a day.
Example three:
a health food for inhibiting and killing helicobacter pylori comprises the following raw materials by weight: 43 parts of chamomile, 37 parts of dandelion, 12 parts of rose, 1 part of preservative and 7 parts of filler.
The preparation method comprises the following steps:
(1) weighing and crushing: cleaning flos Matricariae Chamomillae, herba Taraxaci and flos Rosae Rugosae, air drying, weighing according to proportion, pulverizing respectively, and mixing thoroughly.
(2) Distillation and extraction: adding distilled water into the above mixture, decocting for 1 hr, filtering, removing residue, concentrating the clear liquid, and oven drying to obtain extract.
(3) Grinding and sieving: grinding the above extracts, antiseptic and bulking agent into powder, respectively, mixing, and sieving to obtain powder;
(4) granulating and packaging: granulating the above powders with a granulator, and packaging.
The eating method comprises the following steps: the tea is drunk after being mixed with water or directly eaten twice a day.
Example four:
a health food for inhibiting and killing helicobacter pylori comprises the following raw materials by weight: 50 parts of chamomile, 30 parts of dandelion, 10 parts of rose, 1 part of preservative and 9 parts of filler.
The preparation method comprises the following steps:
(1) weighing and crushing: cleaning flos Matricariae Chamomillae, herba Taraxaci and flos Rosae Rugosae, air drying, weighing according to proportion, pulverizing respectively, and mixing thoroughly.
(2) Distillation and extraction: adding distilled water into the above mixture, decocting for 2 hr, filtering, removing residue, concentrating the clear liquid, and oven drying to obtain extract.
(3) Grinding and sieving: grinding the above extracts, antiseptic and bulking agent into powder, respectively, mixing, and sieving to obtain powder;
(4) granulating and packaging: granulating the above powders with a granulator, and packaging.
The eating method comprises the following steps: the tea is drunk after being mixed with water or directly eaten twice a day.
And (3) counting the curative effect:
110 Hp positive patients are selected as study objects, peptic ulcer is confirmed through gastroscopy, meanwhile, biopsy specimens are taken through an endoscope, HE staining is carried out, and the fast urease test result is diagnosed as Hp positive. All patients were not treated with antibiotics, PPI drugs, 2 weeks before treatment. Wherein, 60 female patients and 50 male patients are selected;
the health food for inhibiting and killing helicobacter pylori is taken twice a day, 14 days is a treatment course, and the taking is two treatment courses.
Judgment of therapeutic effect
And (3) healing: the syndrome integral is reduced by more than or equal to 95 percent, and Hp is basically and completely killed;
the effect is shown: the syndrome integral is reduced by more than or equal to 70 percent, and most of Hp is killed;
the method has the following advantages: the syndrome score is reduced by more than or equal to 30 percent, and a small part of Hp is killed;
and (4) invalidation: the reduction in the syndrome score was < 30% with essentially no effect.
| Cases of disease | Recovery method | Show effect | Is effective | Invalidation | Total effective rate (%) |
| For male | 35 | 7 | 5 | 3 | 94％ |
| Woman | 38 | 11 | 6 | 5 | 91.6％ |
| Total of | 73 | 18 | 11 | 8 | 92.7％ |
In conclusion, the health food for inhibiting and killing the helicobacter pylori, which is prepared by the invention, can effectively inhibit and kill the helicobacter pylori, has simple preparation process, low cost and convenient eating, can be drunk after being mixed with water or directly taken, has no toxic or side effect on the traditional Chinese medicine raw materials, and is suitable for different people to take.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the present invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention should be included in the scope of the present invention.
Claims (6)
1. The health food for inhibiting and killing helicobacter pylori is characterized by comprising the following raw materials in parts by weight: 40-60 parts of chamomile, 30-50 parts of dandelion, 5-20 parts of rose, 1-5 parts of preservative and 1-20 parts of filler.
2. The health food for inhibiting and killing helicobacter pylori according to claim 1, which is prepared from the following raw materials in parts by weight: 45 parts of chamomile, 35 parts of dandelion, 10 parts of rose, 1 part of preservative and 9 parts of filler.
3. The health food for inhibiting and killing helicobacter pylori according to claim 1, which is prepared from the following raw materials in parts by weight: 50 parts of chamomile, 40 parts of dandelion, 5 parts of rose, 1 part of preservative and 4 parts of filler.
4. The health food for inhibiting and killing helicobacter pylori according to any one of claims 1 to 3, wherein the preservative is a food preservative, and the bulking agent is maltodextrin.
5. The health food for inhibiting and killing helicobacter pylori according to claim 4, wherein the preparation method comprises the following steps:
(1) weighing and crushing: cleaning flos Matricariae Chamomillae, herba Taraxaci and flos Rosae Rugosae, air drying, weighing according to proportion, pulverizing respectively, and mixing thoroughly.
(2) Distillation and extraction: adding distilled water into the above mixture, decocting for 1-3 hr, filtering, removing residue, concentrating the clear liquid, and oven drying to obtain extract.
(3) Grinding and sieving: grinding the above extracts, antiseptic and bulking agent into powder, respectively, mixing, and sieving to obtain powder;
(4) granulating and packaging: granulating the above powders with a granulator, and packaging.
6. The health food for inhibiting and killing helicobacter pylori and the preparation method thereof according to claim 5, wherein the health food comprises: the eating method of the health food is tea making or direct eating.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110394832.6A CN113080450A (en) | 2021-04-13 | 2021-04-13 | Health food for inhibiting and killing helicobacter pylori and preparation method thereof |
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| CN202110394832.6A CN113080450A (en) | 2021-04-13 | 2021-04-13 | Health food for inhibiting and killing helicobacter pylori and preparation method thereof |
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| CN113080450A true CN113080450A (en) | 2021-07-09 |
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Cited By (1)
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| CN113679750A (en) * | 2021-08-31 | 2021-11-23 | 花开星辰化妆品(浙江)有限公司 | Application of chamomile hydrolat extract in resisting helicobacter pylori |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113679750A (en) * | 2021-08-31 | 2021-11-23 | 花开星辰化妆品(浙江)有限公司 | Application of chamomile hydrolat extract in resisting helicobacter pylori |
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