CN113018211A - Composition for hair nourishing and protecting and application thereof - Google Patents
Composition for hair nourishing and protecting and application thereof Download PDFInfo
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- CN113018211A CN113018211A CN202110280293.3A CN202110280293A CN113018211A CN 113018211 A CN113018211 A CN 113018211A CN 202110280293 A CN202110280293 A CN 202110280293A CN 113018211 A CN113018211 A CN 113018211A
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- 210000004209 hair Anatomy 0.000 title claims abstract description 64
- 239000000203 mixture Substances 0.000 title claims abstract description 30
- 230000002633 protecting effect Effects 0.000 title claims abstract description 13
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims abstract description 28
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 28
- 229930182494 ginsenoside Natural products 0.000 claims abstract description 22
- 229940089161 ginsenoside Drugs 0.000 claims abstract description 21
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 claims abstract description 15
- RRJOMESUBQAYOA-BZSNNMDCSA-N (2S)-2-[[(2S)-2-[[2-[[(2S)-2-acetamido-6-aminohexanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-6-aminohexanamide Chemical compound NCCCC[C@H](NC(=O)C)C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(N)=O)CC1=CN=CN1 RRJOMESUBQAYOA-BZSNNMDCSA-N 0.000 claims abstract description 14
- MVORZMQFXBLMHM-QWRGUYRKSA-N Gly-His-Lys Chemical compound NCCCC[C@@H](C(O)=O)NC(=O)[C@@H](NC(=O)CN)CC1=CN=CN1 MVORZMQFXBLMHM-QWRGUYRKSA-N 0.000 claims abstract description 14
- 229960002685 biotin Drugs 0.000 claims abstract description 14
- 235000020958 biotin Nutrition 0.000 claims abstract description 14
- 239000011616 biotin Substances 0.000 claims abstract description 14
- 238000000034 method Methods 0.000 claims abstract description 14
- 239000004480 active ingredient Substances 0.000 claims abstract description 8
- 239000012752 auxiliary agent Substances 0.000 claims abstract description 6
- 239000000463 material Substances 0.000 claims abstract description 4
- 230000008569 process Effects 0.000 claims abstract description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 39
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 38
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Natural products CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 11
- 238000001914 filtration Methods 0.000 claims description 10
- 238000010438 heat treatment Methods 0.000 claims description 7
- 230000001737 promoting effect Effects 0.000 claims description 7
- 238000003756 stirring Methods 0.000 claims description 7
- 238000004806 packaging method and process Methods 0.000 claims description 6
- 230000003779 hair growth Effects 0.000 claims description 5
- 239000003755 preservative agent Substances 0.000 claims description 4
- 230000002335 preservative effect Effects 0.000 claims description 3
- DNIAPMSPPWPWGF-VKHMYHEASA-N (+)-propylene glycol Chemical compound C[C@H](O)CO DNIAPMSPPWPWGF-VKHMYHEASA-N 0.000 claims description 2
- 229940015975 1,2-hexanediol Drugs 0.000 claims description 2
- YPFDHNVEDLHUCE-UHFFFAOYSA-N 1,3-propanediol Substances OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 claims description 2
- 229940035437 1,3-propanediol Drugs 0.000 claims description 2
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 2
- 229920000166 polytrimethylene carbonate Polymers 0.000 claims description 2
- 230000003750 conditioning effect Effects 0.000 claims 11
- 235000011187 glycerol Nutrition 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 239000002671 adjuvant Substances 0.000 claims 1
- RGUVUPQQFXCJFC-UHFFFAOYSA-N n-hydroxyoctanamide Chemical compound CCCCCCCC(=O)NO RGUVUPQQFXCJFC-UHFFFAOYSA-N 0.000 claims 1
- 239000003002 pH adjusting agent Substances 0.000 claims 1
- 230000008859 change Effects 0.000 abstract description 5
- 239000002537 cosmetic Substances 0.000 abstract description 2
- 230000003450 growing effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 8
- 201000004384 Alopecia Diseases 0.000 description 7
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 6
- 239000002253 acid Substances 0.000 description 6
- 210000003780 hair follicle Anatomy 0.000 description 6
- 239000012528 membrane Substances 0.000 description 6
- 210000004761 scalp Anatomy 0.000 description 6
- 239000003513 alkali Substances 0.000 description 5
- 238000001816 cooling Methods 0.000 description 5
- 230000006872 improvement Effects 0.000 description 5
- 239000008213 purified water Substances 0.000 description 4
- 210000003491 skin Anatomy 0.000 description 4
- 231100000360 alopecia Toxicity 0.000 description 3
- 230000003698 anagen phase Effects 0.000 description 3
- 208000024963 hair loss Diseases 0.000 description 3
- 230000003676 hair loss Effects 0.000 description 3
- 102100034216 Melanocyte-stimulating hormone receptor Human genes 0.000 description 2
- 101710161100 Melanocyte-stimulating hormone receptor Proteins 0.000 description 2
- 230000032683 aging Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 210000000442 hair follicle cell Anatomy 0.000 description 2
- 210000003128 head Anatomy 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 230000001575 pathological effect Effects 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 230000003797 telogen phase Effects 0.000 description 2
- 206010015150 Erythema Diseases 0.000 description 1
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 1
- 208000015710 Iron-Deficiency Anemia Diseases 0.000 description 1
- 102400000740 Melanocyte-stimulating hormone alpha Human genes 0.000 description 1
- 101710200814 Melanotropin alpha Proteins 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 201000002996 androgenic alopecia Diseases 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 235000004251 balanced diet Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003592 biomimetic effect Effects 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000005238 degreasing Methods 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 231100000321 erythema Toxicity 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 230000037308 hair color Effects 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 210000002510 keratinocyte Anatomy 0.000 description 1
- 210000002752 melanocyte Anatomy 0.000 description 1
- 230000003061 melanogenesis Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 125000002801 octanoyl group Chemical group C(CCCCCCC)(=O)* 0.000 description 1
- 230000003711 photoprotective effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000003223 protective agent Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 229940095673 shampoo product Drugs 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 210000001685 thyroid gland Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- WHNFPRLDDSXQCL-UAZQEYIDSA-N α-msh Chemical compound C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(N)=O)NC(=O)[C@H](CO)NC(C)=O)C1=CC=C(O)C=C1 WHNFPRLDDSXQCL-UAZQEYIDSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention relates to a composition for hair nourishing and protecting and application thereof, belonging to the field of cosmetics, and being characterized by comprising the following active ingredients in percentage by mass: hair nourishing and caring peptide 0.1-2.0%, and ginsenoside 0.1-2.0%; and corresponding auxiliary materials and auxiliary agents; the invention uses four active ingredients of biotin tripeptide-1, acetyl tetrapeptide-3, acetyl hexapeptide-1 and ginsenoside for synergy, unexpectedly improves the hair growing and protecting effect to the hair improving rate of 85.8% from quantitative to qualitative change, only contains four active ingredients, and has simple component process.
Description
Technical Field
The invention relates to the field of cosmetics, in particular to a hair nourishing and protecting composition and application thereof.
Background
Hair and scalp, which are parts of the human body, are the same as skin, and are subject to aging phenomena with age. As the scalp ages, the hair is easily broken and the elasticity is reduced due to the reduction of the elasticity caused by the shortage of oil and water in the hair, or the cuticle is lifted due to the shortage of oil and water in the hair, so that static electricity occurs, the hair tip is branched and the hair becomes dry, or the cuticle outside the hair is damaged and the inner cortex is broken, so that the glossiness of the whole hair is reduced due to the serious diffuse reflection caused by light, or erythema of the scalp occurs, and the hair is separated from the hair follicle of the scalp and does not grow any more. In addition, as the scalp ages, the amount of melanin in the hair decreases or a white hair phenomenon occurs in which melanin is not present.
The causes of alopecia can be divided into two types, one is physiological, which means normal hair loss, and the other is pathological, which means excessive hair loss and abnormal hair. With the increasing social pressure, the pace of life is accelerated, the environment is polluted, the habit of life is bad, and the diet is unbalanced, so that more and more alopecia patients are generated. In general, it is desired to rapidly grow the epilated hair, and it is also possible to promote the growth by physically massaging the scalp and to not use a shampoo product having a strong degreasing power, in addition to maintaining a good living habit, a balanced diet. Another approach is to use hair growth promoting products with strong hair growth promoting and hair growth promoting ability.
At present, in the market, products aiming at hair nourishing and protecting have various functions and effects, most of the products have slow effect, and the safety and sequelae are difficult to predict. If the hair conditioner is improperly used, head skin is easily damaged, and the hair nourishing and protecting effects are unstable.
Disclosure of Invention
The invention aims to solve the technical problem of providing a hair-nourishing and hair-protecting composition with simple components and good effect and application thereof aiming at the defects of the prior art.
The technical scheme for solving the technical problems is as follows: the composition for hair nourishing and protecting is characterized by comprising the following active ingredients in percentage by mass: hair nourishing and caring peptide 0.1-2.0%, and ginsenoside 0.1-2.0%; and corresponding auxiliary materials and auxiliary agents.
Furthermore, the hair nourishing and caring peptide adopts a mixture of biotin tripeptide-1, acetyl tetrapeptide-3 and acetyl hexapeptide-1.
The biotin tripeptide-1 promotes the anti-aging of hair follicle cells by stimulating the metabolism of the hair follicle cells, thereby slowing down the alopecia speed; the hair follicle protective agent has the functions of protecting and repairing the structural components of the hair follicle; promoting the expression of the gene related to the tissue repair mechanism.
The acetyl tetrapeptide-3 can stimulate the natural growth of hair and reduce hair loss; repairing connective tissues of epidermis and dermis, and promoting stability of hair in hair follicle; accelerating the synthesis of extracellular matrix proteins by fibroblasts; directly acts on the tissues around the hair follicle to increase the volume and the length of the hair follicle.
Acetyl hexapeptide-1 has affinity for MC1-R, is a biomimetic peptide mimicking alpha-MSH, and can promote melanogenesis by binding to MC1-R, and thus can be used as a natural photoprotective factor and inflammatory regulator. At the same time, transfer of melanin from melanocytes to keratinocytes can be promoted, and thus coloring of skin or hair can be promoted.
Ginsenoside can make skin smooth, soft and elastic, and delay aging.
Furthermore, the auxiliary materials comprise 1.0-10% of glycerol and 1.0-10% of propylene glycol.
Further, the auxiliary agent comprises a preservative and a pH regulator.
Furthermore, the preservative is PHL which is a mixture of 1, 2-hexanediol, caprylyl hydroximic acid and 1, 3-propanediol.
Further, acetic acid and/or triethanolamine is used as the pH regulator.
Further, the active ingredients consist of the hair nourishing and caring peptide and ginsenoside.
The preparation method of the hair-nourishing and hair-protecting composition comprises the following steps:
adding hair nourishing and caring peptide, ginsenoside, glycerol, propylene glycol, and water into a container, heating to 85 deg.C, and stirring to dissolve;
after the system is cooled to room temperature, adding an auxiliary agent, and adjusting the pH value to be 4.5-6.0;
filtering and subpackaging, wherein the filtering process adopts a 0.22 mu m filter membrane for filtering.
The application of the composition for hair nourishing and protecting is characterized in that the ginsenoside and the hair nourishing and protecting peptide are compounded for increasing the effect of the hair nourishing and protecting peptide on promoting the hair growth.
The invention has the beneficial effects that: the invention only uses four active ingredients of biotin tripeptide-1, acetyl tetrapeptide-3, acetyl hexapeptide-1 and ginsenoside for synergy, unexpectedly improves the effect from quantitative change to qualitative change through different action mechanisms until the hair improvement rate reaches 85.8 percent, and has simple component process.
Drawings
Fig. 1 is a graph of hair improvement data.
Detailed Description
Example 1
Case one Synthesis of 1kg essence
| Component name | Percentage of content |
| Hair-growing and hair-protecting peptide | 0.1％ |
| Ginsenoside | 2.0％ |
| Glycerol | 1.0％ |
| Propylene glycol | 10.0％ |
| PHL | 0.5％ |
| Acetic acid | 1.0％ |
| |
0％ |
| Purified water | Balance of |
The hair-growing and hair-protecting peptide is a mixture of biotin tripeptide-1, acetyl tetrapeptide-3 and acetyl hexapeptide-1, and the mass ratio of the biotin tripeptide-1, the acetyl tetrapeptide-3 and the acetyl hexapeptide-1 is 3:10: 10.
The method comprises the following operation steps:
the method comprises the following steps: adding hair nourishing and caring peptide, ginsenoside, glycerol, propylene glycol, and water into a container, heating to 85 deg.C, and stirring to dissolve;
step two: cooling the system to room temperature, adding PHL, and adjusting pH to 4.5 with acid and alkali (acetic acid and triethanolamine);
step three: filtering (0.22 μm filter membrane) in GMP workshop or superclean bench, and packaging.
Example 2
Case two synthesizes 1kg essence
| Component name | Percentage of content |
| Hair-growing and hair-protecting peptide | 2.0％ |
| Ginsenoside | 0.1％ |
| Glycerol | 10.0％ |
| Propylene glycol | 1.0％ |
| PHL | 1.0％ |
| |
0％ |
| Triethanolamine | 1.0％ |
| Purified water | Balance of |
The hair-growing and hair-protecting peptide is a mixture of biotin tripeptide-1, acetyl tetrapeptide-3 and acetyl hexapeptide-1, and the mass ratio of the biotin tripeptide-1, the acetyl tetrapeptide-3 and the acetyl hexapeptide-1 is 3:10: 10.
The method comprises the following operation steps:
the method comprises the following steps: adding hair nourishing and caring peptide, ginsenoside, glycerol, propylene glycol, and water into a container, heating to 85 deg.C, and stirring to dissolve;
step two: cooling the system to room temperature, adding PHL, and adjusting pH to 6.0 with acid and alkali (acetic acid and triethanolamine);
step three: filtering (0.22 μm filter membrane) in GMP workshop or superclean bench, and packaging.
Example 3
Case three synthesized 1kg essence
| Component name | Percentage of content |
| Hair-growing and hair-protecting peptide | 1.0％ |
| Ginsenoside | 1.0％ |
| Glycerol | 5.0％ |
| Propylene glycol | 5.0％ |
| PHL | 0.75％ |
| Acetic acid | 0.5％ |
| Triethanolamine | 0.5％ |
| Purified water | Balance of |
The hair-growing and hair-protecting peptide is a mixture of biotin tripeptide-1, acetyl tetrapeptide-3 and acetyl hexapeptide-1, and the mass ratio of the biotin tripeptide-1, the acetyl tetrapeptide-3 and the acetyl hexapeptide-1 is 3:10: 10.
The method comprises the following operation steps:
the method comprises the following steps: adding hair nourishing and caring peptide, ginsenoside, glycerol, propylene glycol, and water into a container, heating to 85 deg.C, and stirring to dissolve;
step two: cooling the system to room temperature, adding PHL, and adjusting pH value to 5.0 with acid and alkali (acetic acid and triethanolamine);
step three: filtering (0.22 μm filter membrane) in GMP workshop or superclean bench, and packaging.
Comparative example 1
Case four synthesized 1kg essence
| Component name | Percentage of content |
| Hair-growing and hair-protecting peptide | 2.0％ |
| Glycerol | 5.0％ |
| Propylene glycol | 5.0％ |
| PHL | 0.75％ |
| Acetic acid | 0.5％ |
| Triethanolamine | 0.5％ |
| Purified water | Balance of |
The hair-growing and hair-protecting peptide is a mixture of biotin tripeptide-1, acetyl tetrapeptide-3 and acetyl hexapeptide-1, and the mass ratio of the biotin tripeptide-1, the acetyl tetrapeptide-3 and the acetyl hexapeptide-1 is 3:10: 10.
The method comprises the following operation steps:
the method comprises the following steps: adding hair-growing and hair-protecting peptide, glycerol, propylene glycol and water into a container, heating to 85 ℃, and stirring until the mixture is dissolved;
step two: cooling the system to room temperature, adding PHL, and adjusting pH value to 5.0 with acid and alkali (acetic acid and triethanolamine);
step three: filtering (0.22 μm filter membrane) in GMP workshop or superclean bench, and packaging.
Comparative example 2
Case five synthesized 1kg essence
The method comprises the following operation steps:
the method comprises the following steps: adding ginsenoside, glycerol, propylene glycol and water into a container, heating to 85 deg.C, and stirring to dissolve;
step two: cooling the system to room temperature, adding PHL, and adjusting pH value to 5.0 with acid and alkali (acetic acid and triethanolamine);
step three: filtering (0.22 μm filter membrane) in GMP workshop or superclean bench, and packaging.
Efficacy data:
1. test population
140 volunteers with androgenic alopecia were selected, the average age was 42 years, all volunteers had no iron deficiency anemia, thyroid gland and associated pathological features, and their head hair had not received any treatment. In this experimental area, there were at least 200 hairs, 70% of which were in anagen phase.
2. Sample condition
The essence of the embodiment examples 1-6, the essence of the blank control group and a hair-nourishing and hair-care essence of a certain brand known on the market are respectively tried out from each test group, the tested product is used once after the hair is cleaned in the morning and evening every day, and the test period is 56 days, and the use amount is 5ml each time. Comparing the average density of each group of hair at anagen phase with the average density of each group of hair at telogen phase, the average density of anagen phase and telogen phase, and the hair color ratio on the 0 th day and the 56 th day, the improvement rate is recorded comprehensively as follows:
from the analysis of the data of the chart, the hair improvement rate of the hair nourishing and caring peptide consisting of the mixture of the biotin tripeptide-1, the acetyl tetrapeptide-3 and the acetyl hexapeptide-1 reaches 30.3 percent by singly using the ginsenoside, and the hair improvement rate of the composition compounded by the hair nourishing and caring peptide and the ginsenoside can reach 83.9 to 85.8 percent by singly using the ginsenoside, the effect of the composition is far more than the sum of the single component effects of two elements, the synergistic effect from quantitative change to qualitative change is generated, and the unexpected technical effect is obtained.
Claims (10)
1. The composition for hair nourishing and protecting is characterized by comprising the following active ingredients in percentage by mass: hair nourishing and caring peptide 0.1-2.0%, and ginsenoside 0.1-2.0%; and corresponding auxiliary materials and auxiliary agents.
2. A hair nourishing and caring composition according to claim 1, wherein the hair nourishing and caring peptide is mixture of biotin tripeptide-1, acetyl tetrapeptide-3, and acetyl hexapeptide-1.
3. A hair nourishing and conditioning composition as claimed in claim 1 wherein said adjuvants are glycerin 1.0-10%, propylene glycol 1.0-10%.
4. A hair nourishing and conditioning composition according to claim 1 wherein the adjuncts comprise preservatives, pH adjusters.
5. A hair nourishing and conditioning composition as claimed in claim 4 wherein said preservative is PHL which is a mixture of 1, 2-hexanediol, caprylhydroxamic acid and 1, 3-propanediol.
6. A hair nourishing and conditioning composition according to claim 4, wherein said pH adjusting agent is acetic acid and/or triethanolamine.
7. A hair nourishing and conditioning composition according to claim 1 wherein said active ingredients consist of said hair nourishing and conditioning peptide and ginsenoside.
8. A hair nourishing and conditioning composition according to any of claims 1 to 7, prepared by a process comprising:
adding hair nourishing and caring peptide, ginsenoside, glycerol, propylene glycol, and water into a container, heating to 85 deg.C, and stirring to dissolve;
after the system is cooled to room temperature, adding an auxiliary agent, and adjusting the pH value to be 4.5-6.0;
filtering and packaging.
9. A hair nourishing and conditioning composition according to claim 8, wherein the filtration is performed using a 0.22 μm filter.
10. Use of a hair nourishing and conditioning composition according to any of claims 1 to 7, wherein ginsenosides are used in combination with the hair nourishing and conditioning peptides for increasing the hair growth promoting effect of the hair nourishing and conditioning peptides.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110280293.3A CN113018211A (en) | 2021-03-16 | 2021-03-16 | Composition for hair nourishing and protecting and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110280293.3A CN113018211A (en) | 2021-03-16 | 2021-03-16 | Composition for hair nourishing and protecting and application thereof |
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| Publication Number | Publication Date |
|---|---|
| CN113018211A true CN113018211A (en) | 2021-06-25 |
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|---|---|---|---|
| CN202110280293.3A Pending CN113018211A (en) | 2021-03-16 | 2021-03-16 | Composition for hair nourishing and protecting and application thereof |
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| CN110151592A (en) * | 2019-05-09 | 2019-08-23 | 杭州科腾生物制品有限公司 | A kind of composition and its preparation method and application |
| CN110200838A (en) * | 2019-06-21 | 2019-09-06 | 武汉百思凯瑞生物科技有限公司 | A kind of complex polypeptide nano vesicle and its preparation method and application |
| TW202031244A (en) * | 2019-02-20 | 2020-09-01 | 日商萊依柏有限公司 | Hair Treatment Composition |
| CN112245571A (en) * | 2020-09-16 | 2021-01-22 | 陕西中鸿科瑞再生医学研究院有限公司 | Liposome preparation for blackening hair and preparation method thereof |
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2021
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Application publication date: 20210625 |