CN112957443A - Zhuzhai ancient prescription skin detoxification herbal composition and application thereof - Google Patents

Zhuzhai ancient prescription skin detoxification herbal composition and application thereof Download PDF

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CN112957443A
CN112957443A CN202110150100.2A CN202110150100A CN112957443A CN 112957443 A CN112957443 A CN 112957443A CN 202110150100 A CN202110150100 A CN 202110150100A CN 112957443 A CN112957443 A CN 112957443A
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skin
detoxification
rhizome
herb
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钟东平
唐一心
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Abstract

The invention discloses a Zhuzhai ancient prescription skin detoxification herbal composition and application thereof. The Hmong's skin detoxification herbal composition comprises the following components: bistort rhizome, dahurian patrinia herb, tassel flower, solidago decurrens, fenugreek, Sichuan peppers, ginger, drynaria rhizome, cyrtomium rhizome, suberect spatholobus stem, dandelion, honeysuckle, poria cocos, coptis chinensis, Chinese mahonia, borneol and radix euphorbiae ebracteolatae. The Hmong's skin detoxification herbal composition provided by the invention can treat various intractable skin diseases, such as: various skin severe ulceration, beriberi, skin allergy, congenital roughness of the whole skin, psoriasis, mosquito and insect bites, vaginal itching and the like.

Description

Zhuzhai ancient prescription skin detoxification herbal composition and application thereof
Technical Field
The invention relates to the technical field of Chinese herbal medicine preparations, in particular to a germchit village ancient prescription skin detoxification hundred-herb composition and application thereof.
Background
Skin diseases are one of the common surgical diseases, and patients often suffer great pain due to the fact that effective drug treatment cannot be achieved. For example, stubborn and severe itching skin diseases, severe skin ulceration, dermatophytosis, skin allergy and the like have high morbidity and long course of disease, the pathogenesis relates to a plurality of factors such as genetic immunity, inflammation mediators, nerve mediators, cell proliferation and apoptosis, microcirculation disturbance and the like, the social life of a patient is seriously affected by the stubborn and difficult healing of the disease, the high recurrence rate and the like, great physical and psychological pain is caused, and meanwhile, the disease frequently needs to be treated repeatedly due to repeated attack, and heavy economic burden is also brought to the patient. At present, many treatment medicines, namely traditional Chinese medicines and western medicines, can play a certain role, but cannot be cured radically, are easy to relapse, and have strong drug dependence. There is a need to solve this problem.
Disclosure of Invention
The invention provides a Miao Zi Gu Fang skin detoxification hundred herb composition and application thereof, and the Miao Zi Gu Fang skin detoxification hundred herb composition provided by the invention can treat various stubborn skin diseases, such as: various skin severe ulceration, beriberi, skin allergy, congenital roughness of the whole skin, psoriasis, mosquito and insect bites, vaginal itching and the like.
The invention aims to provide a Pimpom mongolicum regel skin detoxification herbal composition which comprises the following pure Chinese herbal medicines: bistort rhizome, dahurian patrinia herb, tassel flower, solidago decurrens, fenugreek, Sichuan peppers, ginger, drynaria rhizome, cyrtomium rhizome, suberect spatholobus stem, dandelion, honeysuckle, poria cocos, coptis chinensis, Chinese mahonia, borneol and radix euphorbiae ebracteolatae.
Preferably, the Miao nationality ancient prescription skin detoxification herbal composition comprises the following components in parts by mass: 1-5 parts of bistort rhizome, 1-5 parts of dahurian patrinia herb, 0.5-5 parts of common nightshade herb, 1-5 parts of solidago decurrens, 1-5 parts of fenugreek, 1-5 parts of Sichuan peppers, 0.5-3 parts of ginger, 1-5 parts of rhizoma drynariae, 1-5 parts of cyrtomium rhizome, 1-5 parts of suberect spatholobus stem, 1-5 parts of dandelion, 1-5 parts of honeysuckle, 1-3 parts of poria cocos, 1-5 parts of coptis chinensis, 1-5 parts of Chinese mahonia, 0.25-1 part of borneol and 1-5 parts of radix euphorbiae lantu.
Further preferably, the Miao village ancient prescription skin detoxification herbal composition comprises the following components in parts by mass: 2-4 parts of bistort rhizome, 2-4 parts of dahurian patrinia herb, 1-4 parts of common cephalanoplos herb, 2-4 parts of solidago decurrens, 2-4 parts of fenugreek, 2-4 parts of Sichuan peppers, 1-3 parts of ginger, 2-4 parts of rhizoma drynariae, 2-4 parts of cyrtomium rhizome, 2-4 parts of suberect spatholobus stem, 2-4 parts of dandelion, 2-4 parts of honeysuckle, 1-3 parts of poria cocos, 2-4 parts of coptis chinensis, 2-4 parts of Chinese mahonia, 0.5-1 part of borneol and 2-4 parts of radix euphorbiae ebracteolatae.
Further preferably, the Miao village ancient prescription skin detoxification herbal composition comprises the following components in parts by mass: 3 parts of bistort rhizome, 3 parts of dahurian patrinia herb, 2.5 parts of common cephalanoplos herb, 3 parts of solidago decurrens, 3 parts of fenugreek, 3 parts of Sichuan peppers, 2 parts of ginger, 3 parts of rhizoma drynariae, 3 parts of cyrtomium rhizome, 3 parts of suberect spatholobus stem, 3 parts of dandelion, 3 parts of honeysuckle, 2 parts of tuckahoe, 3 parts of coptis chinensis, 3 parts of mahonia fortunei, 0.75 part of borneol and 3 parts of radix euphorbiae ebracteolatae.
The invention also protects the application of the Miaozhaigufang skin detoxification herbal composition in preparing medicines for treating skin diseases. The skin diseases include various stubborn extreme itching skin diseases, severe skin ulceration, dermatophytosis, skin allergy, congenital roughness of the whole body skin, psoriasis, mosquito bites and vaginal extreme itching.
Preferably, the medicament is skin detoxification herbal powder or skin detoxification herbal ointment. Preparing into skin toxin-removing herbal powder or skin toxin-removing herbal paste according to actual needs. The preparation method of the skin detoxification herbal powder comprises the steps of uniformly mixing the components, and decocting for 2-4 hours to obtain the skin detoxification herbal powder. The preparation method of the skin detoxification herbal ointment comprises the steps of mixing bistort rhizome, patrinia herb, emilia sonchifolia, solidago decurrens, fenugreek, Sichuan peppers, ginger, drynaria rhizome, cyrtomium rhizome, suberect spatholobus stem, dandelion, honeysuckle, poria cocos, coptis chinensis and Chinese mahonia, soaking in cold water for 10-30 minutes, taking out, boiling in boiling water for 15-30 minutes, extracting, mixing borneol and radix euphorbiae lantu, and obtaining the skin detoxification herbal ointment. The herbal ointment for skin detoxification can be directly applied to the affected part by using the medicine bag. Or soaking and bathing with skin detoxicating herbal powder for about 30 minutes. Or applying the skin detoxicating herbal paste on the affected part 2-5 times a day.
Preferably, the medicament is a skin external preparation prepared by taking the skin detoxification centella composition as an active component and adding pharmaceutically conventional auxiliary materials or auxiliary components.
Compared with the prior art, the invention has the beneficial effects that: the skin detoxification herbal composition provided by the invention can be used for treating various intractable skin diseases, such as: various skin severe ulceration, beriberi, skin allergy, congenital roughness of the whole skin, psoriasis, mosquito and insect bites, vaginal itching and the like. Can radically cure various skin diseases without relapse.
Detailed Description
The following examples are further illustrative of the present invention and are not intended to be limiting thereof. The equipment and reagents used in the present invention are, unless otherwise specified, conventional commercial products in the art.
Example 1
The Miao nationality ancient prescription skin detoxification herbal composition comprises the following components: 1g of bistort rhizome, 1g of dahurian patrinia herb, 0.5g of tasselflower lysimachia herb, 5g of solidago decurrens, 5g of fenugreek, 5g of Sichuan peppers, 0.5g of ginger, 1g of drynaria rhizome, 1g of cyrtomium fortunei, 1g of suberect spatholobus stem, 1g of dandelion, 1g of honeysuckle, 3 g of tuckahoe, 5g of coptis root, 5g of mahonia fortunei, 0.25 g of borneol and 5g of radix euphorbiae ebracteolatae.
Mixing the above components uniformly, pulverizing, and sieving with 80-100 mesh sieve to obtain detoxicating pulvis Fumi Carbonisatus for skin.
Example 2
The Miao nationality ancient prescription skin detoxification herbal composition comprises the following components: 5g of bistort rhizome, 5g of dahurian patrinia herb, 5g of tasselflower bugleweed herb, 1g of solidago decurrens, 1g of fenugreek, 1g of Sichuan peppers, 3 g of ginger, 5g of drynaria rhizome, 5g of cyrtomium rhizome, 5g of suberect spatholobus stem, 5g of dandelion, 5g of honeysuckle flower, 1g of tuckahoe, 1g of coptis root, 1g of mahonia fortunei, 1g of borneol and 1g of radix euphorbiae ebracteolatae.
Mixing the above components uniformly, pulverizing, and sieving with 80-100 mesh sieve to obtain detoxicating pulvis Fumi Carbonisatus for skin.
Example 3
The Miao nationality ancient prescription skin detoxification herbal composition comprises the following components: 2 g of bistort rhizome, 2 g of dahurian patrinia herb, 1g of tasselflower lysimachia herb, 2 g of solidago decurrens, 4 g of fenugreek, 4 g of Sichuan peppery seed, 3 g of ginger, 4 g of drynaria rhizome, 2 g of cyrtomium rhizome, 2 g of suberect spatholobus stem, 4 g of dandelion, 4 g of honeysuckle flower, 3 g of tuckahoe, 4 g of coptis root, 2 g of mahonia fortunei, 0.5g of borneol and 2 g of radix euphorbiae ebracteolatae.
Mixing bistort rhizome, dahurian patrinia herb, emilia sonchifolia, solidago decurrens, fenugreek, Sichuan peppers, ginger, drynaria rhizome, cyrtomium rhizome, suberect spatholobus stem, dandelion, honeysuckle flower, Indian buead, golden thread and Chinese mahonia, then soaking in cold water for 10 minutes, taking out, boiling in boiling water for 30 minutes, extracting, mixing borneol and radix euphorbiae lantu to obtain the skin detoxification herbal ointment.
Example 4
The Miao nationality ancient prescription skin detoxification herbal composition comprises the following components: 4 g of bistort rhizome, 4 g of dahurian patrinia herb, 4 g of tasselflower lysimachia herb, 4 g of solidago decurrens, 2 g of fenugreek, 2 g of Sichuan peppery seed, 1g of ginger, 2 g of drynaria rhizome, 4 g of cyrtomium rhizome, 4 g of suberect spatholobus stem, 2 g of dandelion, 2 g of honeysuckle, 1g of tuckahoe, 2 g of coptis root, 4 g of mahonia fortunei, 1g of borneol and 4 g of radix euphorbiae ebracteolatae.
Mixing bistort rhizome, dahurian patrinia herb, emilia sonchifolia, solidago decurrens, fenugreek, Sichuan peppers, ginger, drynaria rhizome, cyrtomium rhizome, suberect spatholobus stem, dandelion, honeysuckle flower, Indian buead, golden thread and Chinese mahonia, then soaking in cold water for 30 minutes, taking out, boiling in boiling water for 15 minutes, extracting, then mixing borneol and radix euphorbiae lantu to obtain the skin detoxification herbal ointment.
Example 5
The Miao nationality ancient prescription skin detoxification herbal composition comprises the following components: 3 g of bistort rhizome, 3 g of dahurian patrinia herb, 2.5 g of emilia sonchifolia, 3 g of solidago decurrens, 3 g of fenugreek, 3 g of Sichuan peppers, 2 g of ginger, 3 g of drynaria rhizome, 3 g of cyrtomium rhizome, 3 g of suberect spatholobus stem, 3 g of dandelion, 3 g of honeysuckle, 2 g of tuckahoe, 3 g of coptis root, 3 g of mahonia fortunei, 0.75 g of borneol and 3 g of radix euphorbiae ebracteolatae.
Mixing the above components uniformly, pulverizing, and sieving with 80-100 mesh sieve to obtain detoxicating pulvis Fumi Carbonisatus for skin. Or mixing the above components uniformly, and decocting for 4 hr to obtain the final product.
The skin detoxification herbal ointment prepared in example 5 is subjected to an acute skin irritation test, and the test method and the test result are as follows:
according to section 6.3 of the skin irritation/corrosion test of the second part of the 'cosmetic hygiene Specification' (2002) of Ministry of health, 4 male big-ear white rabbits with the weight of 2-3Kg are directly smeared on the skin of one side of an animal (the other side is used as a control) according to the method of the 'acute transdermal toxicity test', the sealing test is adopted for 4 hours, after the test is finished, the residual test object is washed by warm water, the skin reactions of the test area and the control area of the animal are respectively observed after the test object is removed for 1 hour, 24 hours, 48 hours and 72 hours, the highest integral mean value is '0', and the irritation of the skin detoxification herbal composition provided by the invention to the skin of the animal is judged.
The skin detoxification herbal ointment prepared in example 5 is subjected to an allergy test, and the test method and the test result are as follows:
taking 18 healthy mice, weighing 300g of 250-one mice respectively, using the mice as both male and female mice, removing back hair on two sides before a test, dividing the mice into a test group, a blank control group and a positive control group randomly, wherein the positive control group uses 2, 4-dinitrobenzene, the appropriate amount of 2, 4-dinitrobenzene with the mass fraction of 1 percent for sensitization and the 2, 4-dinitrobenzene with the mass fraction of 0.1 percent for excitation. The skin detoxification herbal ointment in the example 5 is applied to the hair removal area of the back, 0.1g of the skin detoxification herbal ointment is applied each time, once a day and three times, 14 days after the last contact, 0.1g of the ointment in the example 5 is applied to the same area of the back, after 6 hours, the medicine is removed, and then the skin detoxification herbal ointment is observed for anaphylactic reaction or not at 24 hours, 48 hours and 72 hours. The positive control group uses the same method to stimulate smearing and observation. The positive control group animal skin shows localized erythema and slight edema after 1h of sensitization, and the test group animal skin has no reaction. The toxin-removing herbal ointment for skin provided by the invention is judged not to cause anaphylactic reaction to skin.
In order to verify the clinical efficacy, the skin-detoxifying herbal powder prepared in example 5 contains 5g of the skin-detoxifying herbal powder per drug package, and the clinical observation shows that the beriberi treatment is carried out on 112 patients, wherein 66 patients and 46 patients are randomly divided into 70 patients in a treatment group and 42 patients in a control group, the age is 15-70 years, the average age is 41 years, the course of disease is 2-20 months, and the general period is 2-3 months. The use method of the medicine package comprises the following steps: soaking a bag of medicinal bag (5g of skin detoxicating herbal powder) in cold water for 20 min, taking out, decocting with hot water for 20 min, soaking feet for 30 min after the hot water is cooled slightly, 1 time per day, and standing for 15 days. After 15 days of treatment, 60 of 66 cases in the treatment group are cured and account for 90.91 percent, and 10 of 46 cases in the control group are cured and account for 21.79 percent. The herbal powder for skin detoxification prepared in the example 5 has obvious curative effect on beriberi, and the beriberi does not relapse after being reflected by a well-treated patient.
The above is only a preferred embodiment of the present invention, and it should be noted that the above preferred embodiment should not be considered as limiting the present invention, and the protection scope of the present invention should be subject to the scope defined by the claims. It will be apparent to those skilled in the art that various modifications and adaptations can be made without departing from the spirit and scope of the invention, and these modifications and adaptations should be considered within the scope of the invention.

Claims (8)

1. The germchit village ancient prescription skin detoxification herbal composition is characterized by comprising the following components: bistort rhizome, dahurian patrinia herb, tassel flower, solidago decurrens, fenugreek, Sichuan peppers, ginger, drynaria rhizome, cyrtomium rhizome, suberect spatholobus stem, dandelion, honeysuckle, poria cocos, coptis chinensis, Chinese mahonia, borneol and radix euphorbiae ebracteolatae.
2. The Miao nationality ancient prescription skin detoxification herbal composition according to claim 1, which is characterized by comprising the following components in parts by mass: 1-5 parts of bistort rhizome, 1-5 parts of dahurian patrinia herb, 0.5-5 parts of common nightshade herb, 1-5 parts of solidago decurrens, 1-5 parts of fenugreek, 1-5 parts of Sichuan peppers, 0.5-3 parts of ginger, 1-5 parts of rhizoma drynariae, 1-5 parts of cyrtomium rhizome, 1-5 parts of suberect spatholobus stem, 1-5 parts of dandelion, 1-5 parts of honeysuckle, 1-3 parts of poria cocos, 1-5 parts of coptis chinensis, 1-5 parts of Chinese mahonia, 0.25-1 part of borneol and 1-5 parts of radix euphorbiae lantu.
3. The Miao nationality ancient prescription skin detoxification herbal composition according to claim 2, which is characterized by comprising the following components in parts by mass: 2-4 parts of bistort rhizome, 2-4 parts of dahurian patrinia herb, 1-4 parts of common cephalanoplos herb, 2-4 parts of solidago decurrens, 2-4 parts of fenugreek, 2-4 parts of Sichuan peppers, 1-3 parts of ginger, 2-4 parts of rhizoma drynariae, 2-4 parts of cyrtomium rhizome, 2-4 parts of suberect spatholobus stem, 2-4 parts of dandelion, 2-4 parts of honeysuckle, 1-3 parts of poria cocos, 2-4 parts of coptis chinensis, 2-4 parts of Chinese mahonia, 0.5-1 part of borneol and 2-4 parts of radix euphorbiae ebracteolatae.
4. The Miao village ancient prescription skin detoxification hundred grass composition according to claim 2 or 3, which is characterized by comprising the following components in parts by mass: 3 parts of bistort rhizome, 3 parts of dahurian patrinia herb, 2.5 parts of common cephalanoplos herb, 3 parts of solidago decurrens, 3 parts of fenugreek, 3 parts of Sichuan peppers, 2 parts of ginger, 3 parts of rhizoma drynariae, 3 parts of cyrtomium rhizome, 3 parts of suberect spatholobus stem, 3 parts of dandelion, 3 parts of honeysuckle, 2 parts of tuckahoe, 3 parts of coptis chinensis, 3 parts of mahonia fortunei, 0.75 part of borneol and 3 parts of radix euphorbiae ebracteolatae.
5. Use of the mirabilis eupatorium composition of claim 1 for preparing a medicament for treating a skin disease.
6. The use of the Miao nationality's Laurencia repens composition according to claim 5 in the preparation of a medicament for treating skin diseases, wherein the skin diseases include various intractable and pruritic skin diseases, severe skin ulceration, beriberi, skin allergy, general skin congenital roughness, psoriasis, mosquito and insect bites, and vaginal itching.
7. The use of the Miaozhaigufang herbal skin detoxification composition according to claim 5, wherein the medicament is herbal skin detoxification powder or herbal skin detoxification paste for the preparation of a medicament for treating skin diseases.
8. The application of the Miao nationality ancient prescription skin detoxification hundred herb composition in the preparation of the medicine for treating skin diseases according to claim 5, wherein the medicine is a skin external preparation prepared by taking the skin detoxification hundred herb composition as an active component and adding pharmaceutically conventional auxiliary materials or auxiliary components.
CN202110150100.2A 2021-02-03 2021-02-03 Zhuzhai ancient prescription skin detoxification herbal composition and application thereof Pending CN112957443A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1273111A (en) * 2000-03-30 2000-11-15 朱江 Ointment for treating skin tinea
CN101337015A (en) * 2007-07-06 2009-01-07 陆荣政 Traditional Chinese medicine for gynecology and dermatology and preparation method thereof
CN104207408A (en) * 2014-08-27 2014-12-17 茹晖 Health-care massage sole and manufacturing method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1273111A (en) * 2000-03-30 2000-11-15 朱江 Ointment for treating skin tinea
CN101337015A (en) * 2007-07-06 2009-01-07 陆荣政 Traditional Chinese medicine for gynecology and dermatology and preparation method thereof
CN104207408A (en) * 2014-08-27 2014-12-17 茹晖 Health-care massage sole and manufacturing method thereof

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