CN112945957A - High-precision microscopic scanning platform capable of automatically loading slide - Google Patents

High-precision microscopic scanning platform capable of automatically loading slide Download PDF

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Publication number
CN112945957A
CN112945957A CN202110171475.7A CN202110171475A CN112945957A CN 112945957 A CN112945957 A CN 112945957A CN 202110171475 A CN202110171475 A CN 202110171475A CN 112945957 A CN112945957 A CN 112945957A
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CN
China
Prior art keywords
slide
axis
plate
movable plate
positioning groove
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110171475.7A
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Chinese (zh)
Inventor
詹晓春
詹斯喻
付凤霞
王静
张海燕
岳文成
孙定勇
孙国清
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhengzhou Zhongpu Medical Equipment Co ltd
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Zhengzhou Zhongpu Medical Equipment Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Zhengzhou Zhongpu Medical Equipment Co ltd filed Critical Zhengzhou Zhongpu Medical Equipment Co ltd
Priority to CN202110171475.7A priority Critical patent/CN112945957A/en
Publication of CN112945957A publication Critical patent/CN112945957A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/24Base structure
    • G02B21/26Stages; Adjusting means therefor
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/34Microscope slides, e.g. mounting specimens on microscope slides

Abstract

The invention relates to a high-precision microscopic scanning platform for automatically loading a slide, which comprises a Z-axis mechanism, an X-axis mechanism and a Y-axis mechanism; the Z-axis mechanism comprises a Z-axis fixing plate and a Z-axis lead screw nut mechanism; the X-axis mechanism comprises an X-axis movable plate and an X-axis screw nut mechanism, and the X-axis movable plate is assembled on the Z-axis screw nut mechanism in a sliding manner; the Y-axis mechanism comprises a glass carrying table, a Y-axis movable plate and a Y-axis lead screw nut mechanism, and the Y-axis movable plate is assembled in the X-axis lead screw nut mechanism in a sliding manner; the glass carrying table is assembled in the Y-axis screw nut mechanism in a sliding manner; the glass carrying table is provided with a slide positioning groove for inserting a slide, and the bottom of the slide positioning groove is provided with an avoiding groove which is arranged in a run-through manner in the slide inserting direction. The invention can automatically load the slide rapidly, the three-axis mechanism can accurately and rapidly convey the slide to the scanning position, the objective lens can be rapidly switched at any time according to the type of the slide, the automation degree is high, the positioning is accurate, the speed is high, and the requirement of large-scale continuous scanning can be met.

Description

High-precision microscopic scanning platform capable of automatically loading slide
Technical Field
The invention relates to the technical field of slide scanning detection, in particular to a high-precision microscopic scanning platform capable of automatically loading slides.
Background
The automation degree of slide sample scanning is higher and higher, automatic equipment is arranged in slide sample production, dyeing and scanning links, slide scanning efficiency is improved, and personnel infection risks are reduced, but problems exist in the slide scanning link, for example, the full-automatic slide production, dyeing and scanning system disclosed by the invention patent of the publication number CN111551756A (the same applicant as the present application) can realize the automation of slide production, dyeing and scanning, a mechanical arm is adopted in the slide scanning link to grab a slide from a slide box for scanning, and a slide glass table can be moved up and down and left and right to adjust the slide position. However, the position of the sample on the slide is deviated, and a part of slide sample after the position of the glass carrying table is adjusted still cannot be scanned comprehensively, so that a certain scanning blind area exists. Different types of slide samples need to be scanned by using different types of scanning objective lenses, some scanning devices capable of adjusting the objective lenses are also available in the market, for example, a full-automatic microscope scanning system without a stage disclosed in the invention patent of publication No. CN107479178A, synchronous belts are adopted to switch the objective lenses to scan different types of slide samples, the rotation precision cannot be guaranteed, the synchronous belts need to be driven by an additional driving mechanism, a plurality of components are added, and the volume of the scanning device is increased. For example, the invention patent of publication number CN110587585A discloses a manipulator device capable of freely grabbing a slide, which adopts multiple sets of screw and nut mechanisms and electric jaws to grab and transfer the slide, and has a complex structure and low slide transfer efficiency, wherein the multiple sets of screw and nut mechanisms occupy the space of the device, and generate more vibration during the operation process, thereby affecting the detection result of the slide.
Disclosure of Invention
The invention aims to provide a high-precision microscopic scanning platform for automatically loading slides, which solves the problems that the conventional slide scanning link cannot adapt to different types of slide scanning and the scanning efficiency is low.
In order to achieve the purpose, the invention adopts the following technical scheme:
a high-precision microscopic scanning platform for automatically loading slides comprises a Z-axis mechanism, an X-axis mechanism and a Y-axis mechanism; the Z-axis mechanism comprises a Z-axis fixing plate and a Z-axis screw nut mechanism arranged on the Z-axis fixing plate; the X-axis mechanism comprises an X-axis movable plate and an X-axis screw and nut mechanism arranged on the X-axis movable plate, and the X-axis movable plate is assembled on the Z-axis screw and nut mechanism in a sliding manner; the Y-axis mechanism comprises a glass carrying table, a Y-axis movable plate and a Y-axis screw nut mechanism arranged on the Y-axis movable plate, and the Y-axis movable plate is assembled in the X-axis screw nut mechanism in a sliding manner; the glass carrying table is assembled in the Y-axis screw nut mechanism in a sliding manner; the glass carrying table is provided with a slide positioning groove for inserting a slide, and an avoiding groove is arranged at the bottom of the slide positioning groove and is communicated in the slide inserting direction.
Further preferably, a slide position sensor is provided in the slide positioning groove.
Preferably, a pushing mechanism is arranged on one side of the slide positioning groove for inserting the slide, the pushing mechanism comprises a slide pushing plate for pushing the slide into the slide positioning groove from the slide box, a slide resetting push plate for pushing the slide back into the slide box from the slide positioning groove, and a pushing mechanism supporting plate, and the slide pushing plate and the slide resetting push plate are respectively arranged at two ends of the pushing mechanism supporting plate.
Further preferably, the slide pushing plate and the slide resetting pushing plate are horizontally arranged at the same height.
Preferably, the avoiding groove comprises a first avoiding groove for the slide pushing plate to enter and exit and a second avoiding groove for the slide resetting push plate to enter and exit.
Further preferably, the widths of the first avoiding groove and the second avoiding groove are smaller than the width of the slide positioning groove.
Further preferably, the depth of the first avoiding groove and the second avoiding groove is greater than the depth of the slide positioning groove.
Further preferably, the Z-axis fixed plate is provided with Z-axis position sensors respectively in the extreme movement direction of the X-axis movable plate; x-axis position sensors are respectively arranged on the X-axis movable plate in the extreme movement direction of the Y-axis movable plate; and Y-axis position sensors are respectively arranged on the Y-axis movable plate in the limit movement direction of the glass carrying table.
Further preferably, a light transmission hole is arranged in the slide positioning groove.
Preferably, a pressing plate is arranged at the position, where the slide is inserted into the slide positioning groove, of the slide positioning groove, a downward bulge is arranged at one end of the pressing plate to press the slide, and the end part of the other end of the pressing plate is tilted upwards to form a guide plate for inserting the slide.
The invention has the beneficial effects that:
the invention relates to a high-precision microscopic scanning platform for automatically loading a slide, which comprises a Z-axis mechanism, an X-axis mechanism and a Y-axis mechanism; the Z-axis mechanism comprises a Z-axis fixing plate and a Z-axis screw nut mechanism arranged on the Z-axis fixing plate; the X-axis mechanism comprises an X-axis movable plate and an X-axis screw and nut mechanism arranged on the X-axis movable plate, and the X-axis movable plate is assembled on the Z-axis screw and nut mechanism in a sliding manner; the Y-axis mechanism comprises a glass carrying table, a Y-axis movable plate and a Y-axis screw nut mechanism arranged on the Y-axis movable plate, and the Y-axis movable plate is assembled in the X-axis screw nut mechanism in a sliding manner; the glass carrying table is assembled in the Y-axis screw nut mechanism in a sliding manner; the glass carrying table is provided with a slide positioning groove for inserting a slide, and the bottom of the slide positioning groove is provided with an avoiding groove which is arranged in a run-through manner in the slide inserting direction.
The high-precision microscopic scanning platform capable of automatically loading the slide can quickly and automatically load the slide, the slide is quickly and accurately conveyed to a scanning position by the three-axis mechanism, the objective lens can be quickly switched at any time according to the type of the slide, the automation degree is high, the positioning is accurate, the speed is high, and the requirement of large-scale continuous scanning can be met.
Drawings
FIG. 1 is a schematic diagram of the structure of a high precision micro-scanning platform for automatically loading slides according to the present invention;
FIG. 2 is a schematic view of the structure of FIG. 1 from another perspective;
FIG. 3 is a schematic diagram of the structure of the high precision micro-scanning platform for automatically loading slides according to the present invention;
FIG. 4 is a schematic view of the structure of the slide table of FIGS. 1-3;
FIG. 5 is a schematic view of the slide push plate in cooperation with the glass slide mount;
FIG. 6 is a schematic view of a slide pusher plate of the high precision micro scanning platform for automatically loading slides according to the present invention;
FIG. 7 is a schematic view of a portion of the structure of a high precision micro scanning platform microscope with an automatically loaded slide according to the present invention.
Names corresponding to the marks in the figure:
1. a Z-axis mechanism, 11, a Z-axis screw and nut mechanism, 12, a Z-axis fixing plate, 111, a first screw, 112, a first servo motor, 13, a base, 121, a Z-axis slide rail, 14, a Z-axis position sensor, 15, a Z-axis sensor induction plate, 16, a Z-axis nut,
2. an X-axis mechanism 21, an X-axis lead screw nut mechanism 22, an X-axis movable plate 23, an X-axis movable plate bracket 211, a second lead screw 212, a second servo motor 221, an X-axis slide rail 24, an X-axis position sensor 25, an X-axis sensor induction plate 26 and an X-axis nut,
3. y-axis mechanism, 31, Y-axis screw-nut mechanism, 32, Y-axis movable plate, 311, third screw, 312, third servo motor, 321, Y-axis slide rail, 33, Y-axis position sensor, 34, Y-axis sensor induction plate, 35, glass carrying table, 351, slide positioning groove, 352, positioning step surface, 353, pressing plate, 354, light hole, 355, back plate, 356, first avoiding groove, 357, slide position sensor, 358, second avoiding groove, 36, Y-axis nut,
4. a slide pushing mechanism 41, a slide pushing plate 42, a slide resetting push plate 43, a push plate screw rod nut mechanism 431, a fourth screw rod 432 and a fourth servo motor,
5. a micro-scanning mirror 51, a switchable objective lens 511, an objective lens gear ring 52, an objective lens conversion device 521, an objective lens conversion motor 522, a motor fixing frame 523 and a motor gear,
6. a visual sensor is arranged on the base plate,
7. a vertical frame, 71 and a clamping groove,
8. and a dripping pipe for immersion lens oil.
Detailed Description
The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention.
Example 1 of the invention:
as shown in fig. 1-6, the high precision micro scanning platform for automatically loading slides comprises an X-axis mechanism 2, a Y-axis mechanism 3, a Z-axis mechanism 1, a micro scanning mirror 5 and a slide pushing mechanism 4.
As shown in fig. 1-3, the Z-axis mechanism 1 includes a Z-axis screw nut mechanism 11 and a Z-axis fixing plate 12, the Z-axis screw nut mechanism 11 is disposed on the Z-axis fixing plate 12, the Z-axis screw nut mechanism 11 includes a lead screw, which is denoted as a first lead screw 111, and drives the lead screw by a first servo motor 112, the Z-axis fixing plate 12 is vertically mounted on the base 13, a Z-axis slide rail 121 is disposed on the Z-axis fixing plate 12, and the Z-axis slide rail 121 is vertically disposed.
Two Z-axis position sensors 14 are arranged on the side surface of the Z-axis fixing plate 12, the Z-axis position sensors 14 are respectively arranged at the limit positions of the X-axis movable plate 22 moving up and down along the Z axis, and a Z-axis sensor induction plate 15 matched with the Z-axis position sensors 14 is arranged on the side surface of the X-axis movable plate 22.
The X-axis mechanism 2 includes an X-axis screw nut mechanism 21 and an X-axis movable plate 22.
The X-axis movable plate 22 is horizontally arranged, an X-axis movable plate bracket 23 is arranged on the lower side of the X-axis movable plate 22, the X-axis movable plate 22 is installed on the X-axis movable plate bracket 23, and the side surface of the X-axis movable plate bracket 23 is fixedly connected with the Z-axis nut 16 in the Z-axis screw nut mechanism 21.
The X-axis movable plate bracket 23 is further provided with a slider matched and slidably connected with the Z-axis slide rail 16, and the X-axis movable plate 22 is slidably assembled on the Z-axis fixed plate 12 along the Z-axis.
The X-axis screw and nut mechanism 21 is fixed on the side of the X-axis movable plate 22, the X-axis screw and nut mechanism 21 includes a lead screw, which is denoted as a second lead screw 211, and a second servo motor 212 drives the lead screw.
The X-axis movable plate 22 is provided with an X-axis slide rail 221, and the X-axis slide rail 221 is horizontally arranged.
As shown in fig. 2, two X-axis position sensors 24 are disposed on the bottom surface of the X-axis movable plate 22, the X-axis position sensors 24 are respectively disposed at the extreme positions of the Y-axis movable plate 32 moving left and right along the X-axis, and an X-axis sensor sensing plate 25 cooperating with the X-axis position sensors 24 is disposed on the X-axis nut 26.
The Y-axis mechanism 3 includes a Y-axis movable plate 32 and a Y-axis screw-nut mechanism 31 mounted on the Y-axis movable plate.
The Y-axis movable plate 32 is provided with a slide block matched with the X-axis slide rail 221, the Y-axis movable plate 32 is slidably assembled on the X-axis movable plate 22, and the Y-axis movable plate 32 horizontally moves along the X-axis slide rail 221.
The Y-axis screw nut mechanism 31 is fixed to the upper side surface of the Y-axis movable plate 32, and includes a lead screw, denoted as a third lead screw 311, and a third servo motor 312 that drives the lead screw.
The Y-axis movable plate 32 is provided with a Y-axis slide rail 321, and the Y-axis slide rail 321 is horizontally arranged.
A screw fixing seat extends from the side of the Y-axis movable plate 32, and the screw fixing seat is also the X-axis nut 26 in the X-axis screw nut mechanism 21. The Y-axis movable plate 32 is slid on the X-axis movable plate 22 by the X-axis screw nut mechanism 21.
The glass carrier 35 is arranged on the Y-axis movable plate 32, a slider engaged with the Y-axis slide rail 321 is arranged on the glass carrier 35, the glass carrier 35 is slidably mounted on the Y-axis movable plate 32, and the glass carrier 35 horizontally moves along the Y-axis slide rail 321.
The glass stage 35 is fixed to a Y-axis nut 36 in the Y-axis screw nut mechanism 31, and the Y-axis screw nut mechanism 31 drives the glass stage 35 to horizontally move in the front-rear direction along the Y-axis slide rail 321.
Two Y-axis position sensors 33 are arranged on the upper side surface of the Y-axis movable plate 32, the Y-axis position sensors 33 are respectively arranged at the limit positions of the glass carrying table 35 moving back and forth along the Y axis, and a Y-axis sensor induction plate 34 matched with the Y-axis position sensors 33 is arranged on the Y-axis nut 36.
As shown in fig. 3, the slide table 35 is provided with a slide positioning groove 351, the slide positioning groove 351 is provided with a positioning step surface 352, and the positioning step surface 352 is used for positioning a slide.
Fig. 4 shows, slide constant head tank four corners is provided with clamp plate 353, and clamp plate 353 one end is provided with decurrent arch for pressing and setting up slide and make the more stable placing of slide in slide constant head tank 35, the other end is close to slide male position, and the perk that makes progress of clamp plate 353 tip forms and supplies slide male deflector, prevents that small error from leading to the slide can't be by the propelling movement to the slide constant head tank in, avoids damaging the slide.
As shown in fig. 4, the bottom of the slide positioning groove 35 is provided with a light hole 354 corresponding to the sample position of the slide for easy scanning by the microscope.
In order to ensure that the slide pushing plate 41 and the slide resetting push plate 42 can smoothly enter and exit the slide positioning groove 35, the following design is made, a first avoiding groove 356 and a second avoiding groove 358 are formed in the bottom of the slide positioning groove 35, the first avoiding groove 356 and the second avoiding groove 358 are arranged in the slide positioning groove 35 in a penetrating manner along the slide entering and exiting direction, the first avoiding groove 356 is used for enabling the slide pushing plate 41 to enter and exit the slide positioning groove 35, the second avoiding groove 358 is used for enabling the slide resetting push plate 42 to enter and exit the slide positioning groove 35, the first avoiding groove 356 and the second avoiding groove 358 are the same in width and are smaller than the width of the slide positioning groove 35. The depth of the first avoiding groove 356 is equal to the thickness of the slide pushing plate 41, and the depth of the second avoiding groove 358 is equal to the thickness of the slide resetting pushing plate 42, so that the slide pushing plate 41 and the slide resetting pushing plate 42 can conveniently enter and exit the slide positioning groove 35. The slide pushing plate 41 rapidly pushes the slide into the slide positioning groove 35, and the slide resetting pushing plate 42 rapidly pushes the slide out of the slide positioning groove 35 after the scanning is finished.
The slide enters the slide positioning slot 35 and the recovery after the scan is completed is accomplished by the slide pusher mechanism 4.
As shown in fig. 5-6, the slide pushing mechanism 4 is a T-shaped plate structure, the slide pushing mechanism 4 includes a slide pushing plate 41 and a slide resetting pushing plate 42, the slide pushing plate 41 is disposed at one end of the T-shaped plate, the slide resetting pushing plate 42 is disposed at the other end of the T-shaped plate, the slide pushing plate 41 is a long plate for pushing a slide in the slide cassette into the slide positioning slot 35, the slide resetting pushing plate 42 is for pushing the slide from the slide positioning slot 35 back into the slide cassette, the slide pushing plate and the slide resetting pushing plate have the same width and are horizontally disposed at the same height, and the slide pushing mechanism 4 is driven by a screw-nut mechanism.
As shown in fig. 3, the vision sensor 6 is arranged above the slide positioning groove 35, the vision sensor 6 is mounted on the stand 7, the clamping groove 71 is arranged on the stand 7, the vision sensor is arranged in the clamping groove 71, the vision sensor can move for a certain distance in the clamping groove 71, the position of the vision sensor 6 can be adjusted according to different slide samples, and the vision recognition of the vision sensor 6 is more accurate. The vision sensor 6 takes a picture of the slide in the slide positioning groove 35, identifies the position of the sample on the slide, and feeds the position back to the control system, and the control system controls the X-axis mechanism 2, the Y-axis mechanism 3 and the Z-axis mechanism 1 to adjust the position of the slide, so that the sample is in a proper scanning range, and the accuracy of the scanning result is improved.
The left side of vision sensor 6 is provided with immersion lens oil dropwise add pipe 8, and immersion lens oil dropwise add pipe 8 sets up on the grudging post, and immersion lens oil dropwise add pipe 8 is arranged in dripping the immersion lens oil on the slide in slide constant head tank 35.
A back plate 355 is arranged below the slide positioning slot 35, and as shown in the figure, the back plate 355 is used for providing an image acquisition background for the vision sensor 6, so that the image is clearer, and meanwhile, the sample and the immersion oil flowing out of the slide can be received, and the cleanness of the interior of the micro scanner is ensured.
As shown in fig. 7, the micro-scanning mirror 5 is disposed above the stage 35, and the micro-scanning mirror 5 includes a switchable objective lens 51 and an objective lens switching device 52.
The objective lens frame is circumferentially provided with an objective lens gear ring 511, the objective lens frame can rotate to be used for switching different objective lenses, the objective lens conversion device 52 is arranged on the microscope support, the objective lens conversion device 52 comprises an objective lens conversion motor 521 and a motor fixing frame 522, the motor fixing frame 522 is arranged on the microscope support, the objective lens conversion motor 521 is arranged in the motor fixing frame 522, a motor gear 523 is arranged on a rotating shaft of the objective lens conversion motor 521, the motor gear 523 is in meshed rotation connection with the objective lens gear ring 511, the objective lens conversion motor 521 rotates to drive the objective lens to rotate to replace the objective lens, different types of slide samples can be scanned, the motor gear 523 is in matched transmission with the objective lens gear ring 511, the efficiency is high, the position adjustment is accurate, and.
The working principle of the high-precision microscopic scanning platform for automatically loading the slide is as follows:
the slide is pushed by a slide pushing plate 41 in a slide pushing mechanism 4 and enters a slide positioning groove 35, after a slide position sensor 357 judges that the slide enters the slide positioning groove 35, a vision sensor 6 shoots the slide, the position of a sample on the slide is judged, slide position information is fed back to a scanning platform, an X-axis mechanism 2, a Y-axis mechanism 3 and a Z-axis mechanism 1 start to work, wherein the Z-axis mechanism 1 moves downwards for a certain distance to avoid the interference of the slide pushing plate 41 on a glass carrying table 35, then the X-axis mechanism 2 and the Y-axis mechanism 3 act to accurately send the slide to the lower part of an objective lens of a microscope, if different objective lenses need to be switched, an objective lens switching motor 521 acts to drive an objective lens frame to rotate to adjust the different objective lenses. After the scanning is finished, the X-axis mechanism 2, the Y-axis mechanism 3 and the Z-axis mechanism 1 reset, the slide positioning groove 35 returns to the initial position, at the moment, the slide resetting push plate 42 in the slide pushing mechanism 4 pushes the slide in the slide positioning groove 35 to return to the slide box, and the automatic scanning of the slide is finished.
The high-precision microscopic scanning platform for automatically loading the slide has the characteristics of compact structure, high transmission efficiency and low fault rate, and compared with the existing mechanical arm structure, the slide pushing mechanism is adopted, so that two processes of conveying the slide to the slide carrying table and returning the slide to the slide box can be completed only by reciprocating motion in one direction of the horizontal plane, the efficiency is greatly improved, the three-axis platform of the slide carrying table has more degrees of freedom, the high-precision microscopic scanning platform is suitable for various slide scanning requirements, the objective lens can be quickly switched, and the slide scanning efficiency is improved.

Claims (10)

1. The utility model provides an automatic high accuracy micro-scanning platform of loading slide which characterized in that: comprises a Z-axis mechanism, an X-axis mechanism and a Y-axis mechanism; the Z-axis mechanism comprises a Z-axis fixing plate and a Z-axis screw nut mechanism arranged on the Z-axis fixing plate; the X-axis mechanism comprises an X-axis movable plate and an X-axis screw and nut mechanism arranged on the X-axis movable plate, and the X-axis movable plate is assembled on the Z-axis screw and nut mechanism in a sliding manner; the Y-axis mechanism comprises a glass carrying table, a Y-axis movable plate and a Y-axis screw nut mechanism arranged on the Y-axis movable plate, and the Y-axis movable plate is assembled in the X-axis screw nut mechanism in a sliding manner; the glass carrying table is assembled in the Y-axis screw nut mechanism in a sliding manner; the glass carrying table is provided with a slide positioning groove for inserting a slide, and an avoiding groove is arranged at the bottom of the slide positioning groove and is communicated in the slide inserting direction.
2. The high precision micro-scanning platform for automatically loading slides as claimed in claim 1, wherein: and a slide position sensor is arranged in the slide positioning groove.
3. The high precision micro-scanning platform for automatically loading slides as claimed in claim 1, wherein: the slide positioning groove is provided with a pushing mechanism at one side for inserting the slide, the pushing mechanism comprises a slide pushing plate for pushing the slide into the slide positioning groove from the slide box, a slide resetting push plate for pushing the slide back into the slide box from the slide positioning groove, and a pushing mechanism supporting plate, and the slide pushing plate and the slide resetting push plate are respectively arranged at two ends of the pushing mechanism supporting plate.
4. The high precision micro-scanning platform for automatically loading slides as claimed in claim 3, wherein: the slide pushing plate and the slide resetting push plate are horizontally arranged at the same height.
5. The high precision micro-scanning platform for automatically loading slides as claimed in claim 3, wherein: the avoiding groove comprises a first avoiding groove for the slide pushing plate to pass in and out and a second avoiding groove for the slide resetting push plate to pass in and out.
6. The high precision micro-scanning platform for automatically loading slides as claimed in claim 5, wherein: the width of the first avoiding groove and the width of the second avoiding groove are both smaller than the width of the slide positioning groove.
7. The high precision micro-scanning platform for automatically loading slides as claimed in claim 5, wherein: the depth of the first avoiding groove and the second avoiding groove is larger than that of the slide positioning groove.
8. The high precision micro-scanning platform for automatically loading slides as claimed in claim 1, wherein: z-axis position sensors are respectively arranged on the Z-axis fixed plate in the extreme motion direction of the X-axis movable plate; x-axis position sensors are respectively arranged on the X-axis movable plate in the extreme movement direction of the Y-axis movable plate; and Y-axis position sensors are respectively arranged on the Y-axis movable plate in the limit movement direction of the glass carrying table.
9. The high precision micro-scanning platform for automatically loading slides as claimed in claim 1, wherein: and a light transmission hole is formed in the slide positioning groove.
10. The high precision micro-scanning platform for automatically loading slides as claimed in claim 1, wherein: the slide positioning groove is provided with a pressing plate at the position where the slide is inserted, one end of the pressing plate is provided with a downward bulge to form pressing on the slide, and the end part of the other end of the pressing plate is upwarped to form a guide plate for inserting the slide.
CN202110171475.7A 2021-02-08 2021-02-08 High-precision microscopic scanning platform capable of automatically loading slide Pending CN112945957A (en)

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CN114324167A (en) * 2021-12-31 2022-04-12 杭州千麦医学检验所有限公司 Chromosome karyotype AI analysis and detection appearance
CN114324167B (en) * 2021-12-31 2024-04-09 杭州千麦医学检验实验室有限公司 Chromosome karyotype AI analysis detector

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