CN112932999A - 一种护肤大鲵混合精油及其制备方法 - Google Patents
一种护肤大鲵混合精油及其制备方法 Download PDFInfo
- Publication number
- CN112932999A CN112932999A CN202110171256.9A CN202110171256A CN112932999A CN 112932999 A CN112932999 A CN 112932999A CN 202110171256 A CN202110171256 A CN 202110171256A CN 112932999 A CN112932999 A CN 112932999A
- Authority
- CN
- China
- Prior art keywords
- parts
- essential oil
- oil
- giant salamander
- mixed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000341 volatile oil Substances 0.000 title claims abstract description 168
- 241000157862 Dicamptodontidae Species 0.000 title claims abstract description 98
- 238000002360 preparation method Methods 0.000 title claims abstract description 37
- 239000003921 oil Substances 0.000 claims abstract description 68
- 235000019198 oils Nutrition 0.000 claims abstract description 68
- 239000000284 extract Substances 0.000 claims abstract description 37
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 33
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims abstract description 32
- 239000002994 raw material Substances 0.000 claims abstract description 30
- 102000008186 Collagen Human genes 0.000 claims abstract description 27
- 108010035532 Collagen Proteins 0.000 claims abstract description 27
- 150000008442 polyphenolic compounds Chemical class 0.000 claims abstract description 27
- 235000013824 polyphenols Nutrition 0.000 claims abstract description 27
- 229920001436 collagen Polymers 0.000 claims abstract description 25
- 150000001413 amino acids Chemical class 0.000 claims abstract description 23
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 19
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 claims abstract description 18
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract description 18
- 239000001540 sodium lactate Substances 0.000 claims abstract description 18
- 229940005581 sodium lactate Drugs 0.000 claims abstract description 18
- 235000011088 sodium lactate Nutrition 0.000 claims abstract description 18
- 241000208152 Geranium Species 0.000 claims abstract description 17
- 229920001184 polypeptide Polymers 0.000 claims abstract description 17
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims abstract description 16
- 229960004889 salicylic acid Drugs 0.000 claims abstract description 16
- 244000144725 Amygdalus communis Species 0.000 claims abstract description 15
- 235000011437 Amygdalus communis Nutrition 0.000 claims abstract description 15
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 claims abstract description 15
- 235000007866 Chamaemelum nobile Nutrition 0.000 claims abstract description 15
- 235000005979 Citrus limon Nutrition 0.000 claims abstract description 15
- 244000131522 Citrus pyriformis Species 0.000 claims abstract description 15
- 241000218691 Cupressaceae Species 0.000 claims abstract description 15
- 241000721662 Juniperus Species 0.000 claims abstract description 15
- 244000178870 Lavandula angustifolia Species 0.000 claims abstract description 15
- 235000010663 Lavandula angustifolia Nutrition 0.000 claims abstract description 15
- 244000042664 Matricaria chamomilla Species 0.000 claims abstract description 15
- 235000007232 Matricaria chamomilla Nutrition 0.000 claims abstract description 15
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 claims abstract description 15
- 241000220317 Rosa Species 0.000 claims abstract description 15
- 244000178231 Rosmarinus officinalis Species 0.000 claims abstract description 15
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 15
- 239000008168 almond oil Substances 0.000 claims abstract description 15
- 229940106189 ceramide Drugs 0.000 claims abstract description 15
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 claims abstract description 15
- 239000003240 coconut oil Substances 0.000 claims abstract description 15
- 235000019864 coconut oil Nutrition 0.000 claims abstract description 15
- 229940119170 jojoba wax Drugs 0.000 claims abstract description 15
- 239000001102 lavandula vera Substances 0.000 claims abstract description 15
- 235000018219 lavender Nutrition 0.000 claims abstract description 15
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 claims abstract description 15
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 15
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 15
- 229940045920 sodium pyrrolidone carboxylate Drugs 0.000 claims abstract description 14
- HYRLWUFWDYFEES-UHFFFAOYSA-M sodium;2-oxopyrrolidine-1-carboxylate Chemical compound [Na+].[O-]C(=O)N1CCCC1=O HYRLWUFWDYFEES-UHFFFAOYSA-M 0.000 claims abstract description 14
- 235000004443 Ricinus communis Nutrition 0.000 claims abstract description 12
- 235000015112 vegetable and seed oil Nutrition 0.000 claims abstract description 10
- 229930003231 vitamin Natural products 0.000 claims abstract description 5
- 235000013343 vitamin Nutrition 0.000 claims abstract description 5
- 239000011782 vitamin Substances 0.000 claims abstract description 5
- 229940088594 vitamin Drugs 0.000 claims abstract description 5
- 150000003722 vitamin derivatives Chemical class 0.000 claims abstract description 5
- 244000269722 Thea sinensis Species 0.000 claims abstract 8
- 238000003756 stirring Methods 0.000 claims description 58
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 36
- 239000011259 mixed solution Substances 0.000 claims description 36
- 238000001816 cooling Methods 0.000 claims description 30
- 238000002156 mixing Methods 0.000 claims description 25
- 238000010438 heat treatment Methods 0.000 claims description 23
- 239000007788 liquid Substances 0.000 claims description 21
- 238000001914 filtration Methods 0.000 claims description 18
- 210000001519 tissue Anatomy 0.000 claims description 18
- 239000000243 solution Substances 0.000 claims description 17
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 12
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 claims description 12
- 235000011121 sodium hydroxide Nutrition 0.000 claims description 12
- 239000006228 supernatant Substances 0.000 claims description 12
- 239000010779 crude oil Substances 0.000 claims description 11
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 10
- 239000002253 acid Substances 0.000 claims description 10
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims description 8
- 210000000988 bone and bone Anatomy 0.000 claims description 6
- 238000006243 chemical reaction Methods 0.000 claims description 6
- 230000001877 deodorizing effect Effects 0.000 claims description 6
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 claims description 6
- 238000007670 refining Methods 0.000 claims description 6
- 229910001220 stainless steel Inorganic materials 0.000 claims description 6
- 239000010935 stainless steel Substances 0.000 claims description 6
- 235000019158 vitamin B6 Nutrition 0.000 claims description 6
- 239000011726 vitamin B6 Substances 0.000 claims description 6
- 229940011671 vitamin b6 Drugs 0.000 claims description 6
- 230000008569 process Effects 0.000 claims description 5
- DZNVIZQPWLDQHI-UHFFFAOYSA-N Citronellyl formate Chemical compound O=COCCC(C)CCC=C(C)C DZNVIZQPWLDQHI-UHFFFAOYSA-N 0.000 claims description 4
- GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 claims description 4
- 229930003270 Vitamin B Natural products 0.000 claims description 4
- QMVPMAAFGQKVCJ-UHFFFAOYSA-N citronellol Chemical compound OCCC(C)CCC=C(C)C QMVPMAAFGQKVCJ-UHFFFAOYSA-N 0.000 claims description 4
- 230000007062 hydrolysis Effects 0.000 claims description 4
- 238000006460 hydrolysis reaction Methods 0.000 claims description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 4
- 230000003472 neutralizing effect Effects 0.000 claims description 4
- -1 pinene Chemical compound 0.000 claims description 4
- 235000019156 vitamin B Nutrition 0.000 claims description 4
- 239000011720 vitamin B Substances 0.000 claims description 4
- 102000004190 Enzymes Human genes 0.000 claims description 3
- 108090000790 Enzymes Proteins 0.000 claims description 3
- 241001465754 Metazoa Species 0.000 claims description 3
- NFLGAXVYCFJBMK-RKDXNWHRSA-N (+)-isomenthone Natural products CC(C)[C@H]1CC[C@@H](C)CC1=O NFLGAXVYCFJBMK-RKDXNWHRSA-N 0.000 claims description 2
- QMVPMAAFGQKVCJ-SNVBAGLBSA-N (R)-(+)-citronellol Natural products OCC[C@H](C)CCC=C(C)C QMVPMAAFGQKVCJ-SNVBAGLBSA-N 0.000 claims description 2
- FQCSIUSICFAMDD-UHFFFAOYSA-N 2-oxopyrrolidine-1-carboxylic acid;sodium Chemical compound [Na].OC(=O)N1CCCC1=O FQCSIUSICFAMDD-UHFFFAOYSA-N 0.000 claims description 2
- 241000251468 Actinopterygii Species 0.000 claims description 2
- 241000283690 Bos taurus Species 0.000 claims description 2
- WTEVQBCEXWBHNA-UHFFFAOYSA-N Citral Natural products CC(C)=CCCC(C)=CC=O WTEVQBCEXWBHNA-UHFFFAOYSA-N 0.000 claims description 2
- GLZPCOQZEFWAFX-YFHOEESVSA-N Geraniol Natural products CC(C)=CCC\C(C)=C/CO GLZPCOQZEFWAFX-YFHOEESVSA-N 0.000 claims description 2
- 239000005792 Geraniol Substances 0.000 claims description 2
- NFLGAXVYCFJBMK-UHFFFAOYSA-N Menthone Chemical compound CC(C)C1CCC(C)CC1=O NFLGAXVYCFJBMK-UHFFFAOYSA-N 0.000 claims description 2
- 240000000528 Ricinus communis Species 0.000 claims description 2
- 241000282887 Suidae Species 0.000 claims description 2
- 239000003513 alkali Substances 0.000 claims description 2
- 125000000539 amino acid group Chemical group 0.000 claims description 2
- JGQFVRIQXUFPAH-UHFFFAOYSA-N beta-citronellol Natural products OCCC(C)CCCC(C)=C JGQFVRIQXUFPAH-UHFFFAOYSA-N 0.000 claims description 2
- 229910052799 carbon Inorganic materials 0.000 claims description 2
- 229940043350 citral Drugs 0.000 claims description 2
- 235000000484 citronellol Nutrition 0.000 claims description 2
- 238000007865 diluting Methods 0.000 claims description 2
- 239000012467 final product Substances 0.000 claims description 2
- WTEVQBCEXWBHNA-JXMROGBWSA-N geranial Chemical compound CC(C)=CCC\C(C)=C\C=O WTEVQBCEXWBHNA-JXMROGBWSA-N 0.000 claims description 2
- ZHYZQXUYZJNEHD-VQHVLOKHSA-N geranic acid Chemical compound CC(C)=CCC\C(C)=C\C(O)=O ZHYZQXUYZJNEHD-VQHVLOKHSA-N 0.000 claims description 2
- 229930008392 geranic acid Natural products 0.000 claims description 2
- 229940113087 geraniol Drugs 0.000 claims description 2
- 230000036541 health Effects 0.000 claims description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 2
- 239000004310 lactic acid Substances 0.000 claims description 2
- 235000014655 lactic acid Nutrition 0.000 claims description 2
- 229930007503 menthone Natural products 0.000 claims description 2
- 235000010755 mineral Nutrition 0.000 claims description 2
- 239000011707 mineral Substances 0.000 claims description 2
- 238000001223 reverse osmosis Methods 0.000 claims description 2
- 239000011573 trace mineral Substances 0.000 claims description 2
- 235000013619 trace mineral Nutrition 0.000 claims description 2
- ZHYZQXUYZJNEHD-UHFFFAOYSA-N trans-geranic acid Natural products CC(C)=CCCC(C)=CC(O)=O ZHYZQXUYZJNEHD-UHFFFAOYSA-N 0.000 claims description 2
- WUOACPNHFRMFPN-UHFFFAOYSA-N alpha-terpineol Chemical compound CC1=CCC(C(C)(C)O)CC1 WUOACPNHFRMFPN-UHFFFAOYSA-N 0.000 claims 1
- SQIFACVGCPWBQZ-UHFFFAOYSA-N delta-terpineol Natural products CC(C)(O)C1CCC(=C)CC1 SQIFACVGCPWBQZ-UHFFFAOYSA-N 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 229940116411 terpineol Drugs 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 6
- 230000003712 anti-aging effect Effects 0.000 abstract description 5
- 230000003020 moisturizing effect Effects 0.000 abstract description 3
- 241001122767 Theaceae Species 0.000 description 19
- 235000001014 amino acid Nutrition 0.000 description 16
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
- 206010053615 Thermal burn Diseases 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 230000001954 sterilising effect Effects 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 239000004359 castor oil Substances 0.000 description 3
- 235000019438 castor oil Nutrition 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 230000018044 dehydration Effects 0.000 description 3
- 238000006297 dehydration reaction Methods 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 235000021323 fish oil Nutrition 0.000 description 3
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 3
- 208000002874 Acne Vulgaris Diseases 0.000 description 2
- 208000010445 Chilblains Diseases 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 206010000496 acne Diseases 0.000 description 2
- 125000003277 amino group Chemical group 0.000 description 2
- 239000010775 animal oil Substances 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
- 238000009833 condensation Methods 0.000 description 2
- 230000005494 condensation Effects 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 230000003467 diminishing effect Effects 0.000 description 2
- 239000003797 essential amino acid Substances 0.000 description 2
- 238000005562 fading Methods 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 230000005808 skin problem Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000037303 wrinkles Effects 0.000 description 2
- 125000005274 4-hydroxybenzoic acid group Chemical group 0.000 description 1
- 208000010444 Acidosis Diseases 0.000 description 1
- 206010003210 Arteriosclerosis Diseases 0.000 description 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- 240000001746 Betula lenta Species 0.000 description 1
- 235000010921 Betula lenta Nutrition 0.000 description 1
- 208000005156 Dehydration Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 108010016626 Dipeptides Proteins 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 241000124033 Salix Species 0.000 description 1
- 229960001138 acetylsalicylic acid Drugs 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000007950 acidosis Effects 0.000 description 1
- 208000026545 acidosis disease Diseases 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 150000001371 alpha-amino acids Chemical class 0.000 description 1
- 235000008206 alpha-amino acids Nutrition 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 150000003862 amino acid derivatives Chemical class 0.000 description 1
- 208000011775 arteriosclerosis disease Diseases 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000010411 cooking Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 235000020776 essential amino acid Nutrition 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000012847 fine chemical Substances 0.000 description 1
- 235000011194 food seasoning agent Nutrition 0.000 description 1
- 125000000524 functional group Chemical group 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 150000001261 hydroxy acids Chemical class 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 239000013067 intermediate product Substances 0.000 description 1
- 230000037356 lipid metabolism Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 201000008383 nephritis Diseases 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 230000007065 protein hydrolysis Effects 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000009758 senescence Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 210000003556 vascular endothelial cell Anatomy 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Abstract
本发明公开了一种护肤大鲵混合精油,其原料按重量份比包括:大鲵提取油10‑20份、薰衣草精油5‑7份、洋甘菊精油6‑8份、玫瑰精油3‑5份、柠檬精油3‑5份、迷迭香精油5‑8份、杜松精油6‑10份、丝柏精油4‑6份、天竺葵精油3‑5份、甜杏仁油荷荷巴油5‑7份、蓖麻籽油6‑8份、椰子油10‑12份、维生素B68‑12份、透明质酸钠7‑11份、茶多酚10‑12份、水16‑22份、多肽8‑12份、水杨酸6‑10份、氨基酸8‑10份、吡咯烷酮羧酸钠2‑4份、乳酸钠2‑4份、水解胶原蛋白8‑14份和神经酰胺8‑12份,本发明涉及大鲵精油制备技术领域。该护肤大鲵混合精油及其制备方法,精油不仅具有滋润的功效,同时还可以起到抗老保湿的作用,提高精油的功效性,在制备大鲵提取油的时候,采用较为简单的方式进行提取。
Description
技术领域
本发明涉及大鲵精油制备技术领域,具体为一种护肤大鲵混合精油及其制备方法。
背景技术
大鲵作为中国特有的珍稀两栖动物,具有很好的药食两用价值,虽然已经实现了大鲵的人工养殖,国家批准部分人工养殖子二代大鲵商业开发利用来促进企业和个人更好的保护该物种,但人们对大鲵的认识有限,大鲵俗称“娃娃鱼”,大鲵的皮肤、肌肉、脏器、骨骼、油脂及其分泌物均可入药,大鲵油含有多种不饱和脂肪酸,呈淡黄色,澄清透明,具有较淡的鱼腥味,经过研究发现,大鲵油可通过抑制过氧化脂质的形成,减轻血管内皮细胞的损伤;可以调节肝脏的脂质代谢,对大鼠的高脂血症和动脉硬化的形成和发展具有预防作用。
现有较多的精油会通过从动植物中的提取物进行加工,传动动物油脂的提取方法有蒸煮法、淡碱水解法、压榨法等,这些方法由于在提取过程中会破坏大鲵功能成分,从而影响鱼油的质量,而且可能存在二次污染问题,较多的精油只是起到一个滋润的作用,其抗衰和保湿的作用较差,使得精油的使用感一般。
发明内容
针对现有技术的不足,本发明提供了一种护肤大鲵混合精油及其制备方法,解决了动物油提取方法会影响鱼油质量,精油功效较少的问题。
为实现以上目的,本发明通过以下技术方案予以实现:一种护肤大鲵混合精油,其原料按重量份比包括:大鲵提取油10-20份、薰衣草精油5-7份、洋甘菊精油6-8份、玫瑰精油3-5份、柠檬精油3-5份、迷迭香精油5-8份、杜松精油6-10份、丝柏精油4-6份、天竺葵精油3-5份、甜杏仁油荷荷巴油5-7份、蓖麻籽油6-8份、椰子油10-12份、维生素B68-12份、透明质酸钠7-11份、茶多酚10-12份、水16-22份、多肽8-12份、水杨酸6-10份、氨基酸8-10份、吡咯烷酮羧酸钠2-4份、乳酸钠2-4份、水解胶原蛋白8-14份和神经酰胺8-12份。
肽是α-氨基酸以肽键连接在一起而形成的化合物,是蛋白质水解的中间产物,由两个氨基酸分子脱水缩合而成的化合物叫做二肽,同理类推还有三肽、四肽、五肽等,通常由10-100个氨基酸分子脱水缩合而成的化合物叫多肽。
水杨酸是一种脂溶性的有机酸,化学式为C7H6O3,外观是白色的结晶粉状物,熔点是158~161℃,存在于自然界的柳树皮、白珠树叶及甜桦树中,是重要的精细化工原料,可用于阿司匹林等药物的制备。
氨基酸,是含有碱性氨基和酸性羧基的有机化合物,化学式是RCHNH2COOH,羧酸碳原子上的氢原子被氨基取代后形成的化合物,氨基酸分子中含有氨基和羧基两种官能团,与羟基酸类似,氨基酸可按照氨基连在碳链上的不同位置而分为α-,β-,γ-,w-...氨基酸,但经蛋白质水解后得到的氨基酸都是α-氨基酸,而且仅有二十二种,包括甘氨酸、丙氨酸、缬氨酸、亮氨酸、异亮氨酸、甲硫氨酸(蛋氨酸)、脯氨酸、色氨酸、丝氨酸、酪氨酸、半胱氨酸、苯丙氨酸、天冬酰胺、谷氨酰胺、苏氨酸、天冬氨酸、谷氨酸、赖氨酸、精氨酸、组氨酸、硒半胱氨酸[1-2]和吡咯赖氨酸[3](仅在少数细菌中发现),它们是构成蛋白质的基本单位。
吡咯烷酮羧酸钠(即PCA-Na)是皮肤中天然存在的物质,是氨基酸衍生物,本身溶于水和乙醇,却不溶于油,具有比较强的吸湿性,也可以从空气中吸收水份,在化妆品中的应用当然是作为保湿剂,它的保湿能力比甘油、丙二醇、山梨醇这些传统保湿剂都要强一些。
乳酸钠是一种化学物质,分子式为C3H5O3Na,分子量112.06,无色或几乎无色的透明液体,能与水、乙醇、甘油溶合,应用于食品的保鲜、保湿、增香及制药原料,也可作为医药用于解除因腹泻脱水、糖尿病、肾炎等症所科生的酸中毒,也用作调味品,酪蛋白塑料的增塑剂、防冻剂、保湿剂、甘油的代用品、醇类防冻剂的防蚀剂。
胶原蛋白经过酶水解可成为水解胶原蛋白(Hydrolyzed Collagen,又称胶原蛋白肽),胶原多肽含有19种氨基酸,[1]其中包括7种成人必需氨基酸和2种幼儿必需的半必需氨基酸;而且氨基酸总量高达90%以上。
优选的,其原料包括以下组分:大鲵提取油15份、薰衣草精油6份、洋甘菊精油7份、玫瑰精油4份、柠檬精油4份、迷迭香精油6份、杜松精油8份、丝柏精油5份、天竺葵精油4份、甜杏仁油荷荷巴油6份、蓖麻籽油7份、椰子油11份、维生素B610份、透明质酸钠9份、茶多酚11份、水19份、多肽10份、水杨酸8份、氨基酸9份、吡咯烷酮羧酸钠3份、乳酸钠3份、水解胶原蛋白11份和神经酰胺10份。
优选的,其原料包括以下组分:大鲵提取油10份、薰衣草精油5份、洋甘菊精油6份、玫瑰精油3份、柠檬精油3份、迷迭香精油5份、杜松精油6份、丝柏精油4份、天竺葵精油3份、甜杏仁油荷荷巴油5份、蓖麻籽油6份、椰子油10份、维生素B682份、透明质酸钠7份、茶多酚10份、水16份、多肽8份、水杨酸6份、氨基酸8份、吡咯烷酮羧酸钠2份、乳酸钠2份、水解胶原蛋白8份和神经酰胺8份。
优选的,其原料包括以下组分:大鲵提取油20份、薰衣草精油7份、洋甘菊精油8份、玫瑰精油5份、柠檬精油5份、迷迭香精油8份、杜松精油10份、丝柏精油6份、天竺葵精油5份、甜杏仁油荷荷巴油7份、蓖麻籽油8份、椰子油12份、维生素B612份、透明质酸钠11份、茶多酚12份、水22份、多肽12份、水杨酸10份、氨基酸10份、吡咯烷酮羧酸钠4份、乳酸钠4份、水解胶原蛋白14份和神经酰胺12份。
优选的,所述乳酸钠为无色或微黄色透明糖浆状液体,其制备方法是在冷却状态下在乳酸中加入氢氧化钠进行中和,置低于50℃下真空浓缩以除去水分80%后约放置一星期,再用氢氧化钠中和,然后稀释至一定浓度即得成品,所述天竺葵精油中含有香茅醇、甲酸香茅酯、松烯、牛儿酸、牻牛儿醇、松油醇、柠檬醛、薄荷酮和多种微量矿物元素。
优选的,所述水解胶原蛋白是从经过健康检疫的动物骨骼和皮肤中提取的,用食用级稀酸洗脱骨骼和皮肤中的矿物质,提纯而成的骨或皮肤胶原蛋白:根据不同的皮肤原料(牛、猪或鱼)用碱或酸处理后,采用高纯度的反渗透水,在一定温度下提取出大分子的胶原蛋白质,再通过特殊的酶水解工艺,有效剪切大分子链,最完整地保留有效的氨基酸基团,而成为分子量在2000-5000道尔顿的水解胶原蛋白。
本发明还公开了一种护肤大鲵混合精油的制备方法,具体包括以下步骤:
S1、大鲵提取油的制备:取大鲵体内的脂肪组织,将其放置于不锈钢夹层锅内,然后通入热蒸气,将内部加热至90-100℃,加热1-2小时,再对加热过后的脂肪组织进行挤压,把所得到的油液过滤、离心,得到大鲵粗油,再将大鲵粗油加热到50-70℃,加入磷酸溶液经充分混合后进入酸炼反应罐,停留10-30分钟后,静置备用,然后将所得大鲵油原料加热到50℃-95℃,加入烧碱溶液,混匀,停留10-30分钟后,静置备用,在常温下加入活性炭,搅拌10-60分钟,脱色、除臭,离心、过滤去渣,得到上清油液,将上清油液进行缓慢搅拌,控制冷却速度,冷却至0℃-10℃左右,冷却时间为12-48小时,得到大鲵提取油;
S2、第一混合液的制备:选取适量的薰衣草精油、洋甘菊精油、玫瑰精油、柠檬精油、迷迭香精油、杜松精油、丝柏精油、天竺葵精油、甜杏仁油荷荷巴油、蓖麻籽油和椰子油,将其原料倒入搅拌机中,启动搅拌机进行搅拌,将搅拌机内部的温度设置为30℃-50℃,搅拌时间设置有1-2小时,搅拌的速率控制在120-160转/分钟,使其充分混合均匀之后,得到第一混合液;
S3、第二混合液的制备:选取适量的茶多酚和水,将其混合均匀,使得茶多酚充分溶于水,然后加入适量的乳酸钠、吡咯烷酮羧酸钠、水杨酸和水解胶原蛋白,启动搅拌机进行搅拌,搅拌机运行时的温度控制在10℃-30℃,搅拌时间为20-40分钟,搅拌的速率控制在100-150转/分钟,然后加入适量的维生素B6、透明质酸钠、多肽、氨基酸和神经酰胺,再次启动搅拌机,搅拌机运行时的温度控制在40℃-60℃,搅拌时间为40-60分钟,搅拌的速率控制在150-220转/分钟,然后关闭搅拌机,将其冷却至室温,即可得到第二混合液;
S4、混合精油的制备:将S2中制得的第一混合液和S3中制得的第二混合液放入高速分散机内进行均匀分散,分散30-50分钟后,倒入S1中制得的大鲵提取油,将其进行混合均匀,并将其温度升至40℃-60℃,搅拌1-2小时后,将其倒出进行过滤,冷却之后即可得到混合精油。
优选的,所述步骤S1中,所述磷酸溶液的浓度为60-90%,所述烧碱溶液的浓度为10%-40%。
有益效果
本发明提供了一种护肤大鲵混合精油及其制备方法。与现有技术相比具备以下有益效果:该护肤大鲵混合精油及其制备方法,通过S1、大鲵提取油的制备:取大鲵体内的脂肪组织,将其放置于不锈钢夹层锅内,然后通入热蒸气,再对加热过后的脂肪组织进行挤压,把所得到的油液过滤、离心,得到大鲵粗油,加入磷酸溶液经充分混合后进入酸炼反应罐,加入烧碱溶液,混匀,在常温下加入活性炭,脱色、除臭,离心、过滤去渣,得到上清油液,将上清油液进行缓慢搅拌,控制冷却速度,大鲵提取油;S2、第一混合液的制备:选取适量的薰衣草精油、洋甘菊精油、玫瑰精油、柠檬精油、迷迭香精油、杜松精油、丝柏精油、天竺葵精油、甜杏仁油荷荷巴油、蓖麻籽油和椰子油,将其原料倒入搅拌机中,启动搅拌机进行搅拌,使其充分混合均匀之后,得到第一混合液;S3、第二混合液的制备:选取适量的茶多酚和水,将其混合均匀,使得茶多酚充分溶于水,然后加入适量的乳酸钠、吡咯烷酮羧酸钠、水杨酸和水解胶原蛋白,启动搅拌机进行搅拌,然后加入适量的维生素B6、透明质酸钠、多肽、氨基酸和神经酰胺,再次启动搅拌机,然后关闭搅拌机,将其冷却至室温,即可得到第二混合液;S4、混合精油的制备:将S2中制得的第一混合液和S3中制得的第二混合液放入高速分散机内进行均匀分散,倒入S1中制得的大鲵提取油,将其进行混合均匀,将其倒出进行过滤,冷却之后即可得到混合精油;具有防治干燥、冻疮、润泽肌肤、杀菌消炎、祛痘、防治修复烫烧伤,美容美颜、紧致靓丽肌肤、祛纹淡斑、养气补血、滋阴补阳、缓解阴寒湿冷、妇科问题、延缓衰老、杀菌消毒的功效,还可以治疗烫烧伤和多种皮肤问题,精油不仅具有滋润的功效,同时还可以起到抗老保湿的作用,提高精油的功效性,在制备大鲵提取油的时候,采用较为简单的方式进行提取,不会破坏大鲵的功效性,同时可以提高鱼油的质量,使得整体的功能性大大提高。
具体实施方式
下面将结合本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
本发明提供三种技术方案:一种护肤大鲵混合精油的制备方法,具体包括以下实施例:
实施例1
S1、大鲵提取油的制备:取大鲵体内的脂肪组织,将其放置于不锈钢夹层锅内,然后通入热蒸气,将内部加热至95℃,加热1.5小时,再对加热过后的脂肪组织进行挤压,把所得到的油液过滤、离心,得到大鲵粗油,再将大鲵粗油加热到60℃,加入磷酸溶液经充分混合后进入酸炼反应罐,停留20分钟后,静置备用,然后将所得大鲵油原料加热到75℃,加入烧碱溶液,混匀,停留20分钟后,静置备用,在常温下加入活性炭,搅拌35分钟,脱色、除臭,离心、过滤去渣,得到上清油液,将上清油液进行缓慢搅拌,控制冷却速度,冷却至5℃左右,冷却时间为30小时,得到大鲵提取油;
S2、第一混合液的制备:选取6份薰衣草精油、67份洋甘菊精油、4份玫瑰精油、4份柠檬精油、6份迷迭香精油、8份杜松精油、5份丝柏精油、4份天竺葵精油、6份甜杏仁油荷荷巴油、7份蓖麻籽油和11份椰子油,将其原料倒入搅拌机中,启动搅拌机进行搅拌,将搅拌机内部的温度设置为40℃,搅拌时间设置有1.5小时,搅拌的速率控制在140转/分钟,使其充分混合均匀之后,得到第一混合液;S3、第二混合液的制备:选取11份茶多酚和19份水,将其混合均匀,使得茶多酚充分溶于水,然后加入3份乳酸钠、3份吡咯烷酮羧酸钠、8份水杨酸和11份水解胶原蛋白,启动搅拌机进行搅拌,搅拌机运行时的温度控制在20℃,搅拌时间为30分钟,搅拌的速率控制在125转/分钟,然后加入10份维生素B6、9份透明质酸钠、10份多肽、9份氨基酸和10份神经酰胺,再次启动搅拌机,搅拌机运行时的温度控制在50℃,搅拌时间为50分钟,搅拌的速率控制在185转/分钟,然后关闭搅拌机,将其冷却至室温,即可得到第二混合液;
S4、混合精油的制备:将S2中制得的第一混合液和S3中制得的第二混合液放入高速分散机内进行均匀分散,分散40分钟后,倒入S1中制得的大鲵提取油,将其进行混合均匀,并将其温度升至50℃,搅拌1.5小时后,将其倒出进行过滤,冷却之后即可得到混合精油。
实施例2
S1、大鲵提取油的制备:取大鲵体内的脂肪组织,将其放置于不锈钢夹层锅内,然后通入热蒸气,将内部加热至90℃,加热1小时,再对加热过后的脂肪组织进行挤压,把所得到的油液过滤、离心,得到大鲵粗油,再将大鲵粗油加热到50℃,加入磷酸溶液经充分混合后进入酸炼反应罐,停留10分钟后,静置备用,然后将所得大鲵油原料加热到50℃,加入烧碱溶液,混匀,停留10分钟后,静置备用,在常温下加入活性炭,搅拌10分钟,脱色、除臭,离心、过滤去渣,得到上清油液,将上清油液进行缓慢搅拌,控制冷却速度,冷却至0℃左右,冷却时间为12小时,得到大鲵提取油;
S2、第一混合液的制备:选取5份薰衣草精油、6份洋甘菊精油、3份玫瑰精油、3份柠檬精油、5份迷迭香精油、6份杜松精油、4份丝柏精油、3份天竺葵精油、5份甜杏仁油荷荷巴油、6份蓖麻籽油和10份椰子油,将其原料倒入搅拌机中,启动搅拌机进行搅拌,将搅拌机内部的温度设置为30℃,搅拌时间设置有1小时,搅拌的速率控制在120转/分钟,使其充分混合均匀之后,得到第一混合液;S3、第二混合液的制备:选取10份茶多酚和16份水,将其混合均匀,使得茶多酚充分溶于水,然后加入2份乳酸钠、2份吡咯烷酮羧酸钠、6份水杨酸和8份水解胶原蛋白,启动搅拌机进行搅拌,搅拌机运行时的温度控制在10℃,搅拌时间为20分钟,搅拌的速率控制在100转/分钟,然后加入8份维生素B6、7份透明质酸钠、8份多肽、8份氨基酸和8份神经酰胺,再次启动搅拌机,搅拌机运行时的温度控制在40℃,搅拌时间为40分钟,搅拌的速率控制在150转/分钟,然后关闭搅拌机,将其冷却至室温,即可得到第二混合液;
S4、混合精油的制备:将S2中制得的第一混合液和S3中制得的第二混合液放入高速分散机内进行均匀分散,分散30分钟后,倒入S1中制得的大鲵提取油,将其进行混合均匀,并将其温度升至40℃,搅拌1小时后,将其倒出进行过滤,冷却之后即可得到混合精油。
实施例3
S1、大鲵提取油的制备:取大鲵体内的脂肪组织,将其放置于不锈钢夹层锅内,然后通入热蒸气,将内部加热至100℃,加热2小时,再对加热过后的脂肪组织进行挤压,把所得到的油液过滤、离心,得到大鲵粗油,再将大鲵粗油加热到70℃,加入磷酸溶液经充分混合后进入酸炼反应罐,停留30分钟后,静置备用,然后将所得大鲵油原料加热到95℃,加入烧碱溶液,混匀,停留30分钟后,静置备用,在常温下加入活性炭,搅拌60分钟,脱色、除臭,离心、过滤去渣,得到上清油液,将上清油液进行缓慢搅拌,控制冷却速度,冷却至10℃左右,冷却时间为48小时,得到大鲵提取油;
S2、第一混合液的制备:选取7份薰衣草精油、8份洋甘菊精油、5份玫瑰精油、5份柠檬精油、8份迷迭香精油、10份杜松精油、6份丝柏精油、5份天竺葵精油、7份甜杏仁油荷荷巴油、8份蓖麻籽油和2份椰子油,将其原料倒入搅拌机中,启动搅拌机进行搅拌,将搅拌机内部的温度设置为50℃,搅拌时间设置有2小时,搅拌的速率控制在160转/分钟,使其充分混合均匀之后,得到第一混合液;
S3、第二混合液的制备:选取12份茶多酚和22份水,将其混合均匀,使得茶多酚充分溶于水,然后加入4份乳酸钠、份吡咯烷酮羧酸钠、10份水杨酸和14份水解胶原蛋白,启动搅拌机进行搅拌,搅拌机运行时的温度控制在30℃,搅拌时间为40分钟,搅拌的速率控制在150转/分钟,然后加入12份维生素B6、11份透明质酸钠、12份多肽、10份氨基酸和12份神经酰胺,再次启动搅拌机,搅拌机运行时的温度控制在60℃,搅拌时间为60分钟,搅拌的速率控制在220转/分钟,然后关闭搅拌机,将其冷却至室温,即可得到第二混合液;
S4、混合精油的制备:将S2中制得的第一混合液和S3中制得的第二混合液放入高速分散机内进行均匀分散,分散50分钟后,倒入S1中制得的大鲵提取油,将其进行混合均匀,并将其温度升至60℃,搅拌2小时后,将其倒出进行过滤,冷却之后即可得到混合精油。
对比实验
随机选取市场上的护肤大鲵混合精油作为对照组,然后分别对其保湿性、抗衰性和使用感进行测试,且检测条件和上述一致,然后记录其结果,并在相同的时间以及条件下进行操作,在检测的过程中,同时统计数据并制作统计表,见下表。
由上表可知,本发明制备的护肤大鲵混合精油护肤大鲵混合精油具有防治干燥、冻疮、润泽肌肤、杀菌消炎、祛痘、防治修复烫烧伤,美容美颜、紧致靓丽肌肤、祛纹淡斑、养气补血、滋阴补阳、缓解阴寒湿冷、妇科问题、延缓衰老、杀菌消毒的功效,还可以治疗烫烧伤和多种皮肤问题,精油不仅具有滋润的功效,同时还可以起到抗老保湿的作用,提高精油的功效性,在制备大鲵提取油的时候,采用较为简单的方式进行提取,不会破坏大鲵的功效性,同时可以提高鱼油的质量,使得整体的功能性大大提高。
需要说明的是,在本文中,诸如第一和第二等之类的关系术语仅仅用来将一个实体或者操作与另一个实体或操作区分开来,而不一定要求或者暗示这些实体或操作之间存在任何这种实际的关系或者顺序。而且,术语“包括”、“包含”或者其任何其他变体意在涵盖非排他性的包含,从而使得包括一系列要素的过程、方法、物品或者设备不仅包括那些要素,而且还包括没有明确列出的其他要素,或者是还包括为这种过程、方法、物品或者设备所固有的要素。
尽管已经示出和描述了本发明的实施例,对于本领域的普通技术人员而言,可以理解在不脱离本发明的原理和精神的情况下可以对这些实施例进行多种变化、修改、替换和变型,本发明的范围由所附权利要求及其等同物限定。
Claims (8)
1.一种护肤大鲵混合精油,其特征在于:其原料按重量份比包括:大鲵提取油10-20份、薰衣草精油5-7份、洋甘菊精油6-8份、玫瑰精油3-5份、柠檬精油3-5份、迷迭香精油5-8份、杜松精油6-10份、丝柏精油4-6份、天竺葵精油3-5份、甜杏仁油荷荷巴油5-7份、蓖麻籽油6-8份、椰子油10-12份、维生素B68-12份、透明质酸钠7-11份、茶多酚10-12份、水16-22份、多肽8-12份、水杨酸6-10份、氨基酸8-10份、吡咯烷酮羧酸钠2-4份、乳酸钠2-4份、水解胶原蛋白8-14份和神经酰胺8-12份。
2.根据权利要求1所述的一种护肤大鲵混合精油,其特征在于:其原料包括以下组分:大鲵提取油15份、薰衣草精油6份、洋甘菊精油7份、玫瑰精油4份、柠檬精油4份、迷迭香精油6份、杜松精油8份、丝柏精油5份、天竺葵精油4份、甜杏仁油荷荷巴油6份、蓖麻籽油7份、椰子油11份、维生素B610份、透明质酸钠9份、茶多酚11份、水19份、多肽10份、水杨酸8份、氨基酸9份、吡咯烷酮羧酸钠3份、乳酸钠3份、水解胶原蛋白11份和神经酰胺10份。
3.根据权利要求1所述的一种护肤大鲵混合精油,其特征在于:其原料包括以下组分:大鲵提取油10份、薰衣草精油5份、洋甘菊精油6份、玫瑰精油3份、柠檬精油3份、迷迭香精油5份、杜松精油6份、丝柏精油4份、天竺葵精油3份、甜杏仁油荷荷巴油5份、蓖麻籽油6份、椰子油10份、维生素B682份、透明质酸钠7份、茶多酚10份、水16份、多肽8份、水杨酸6份、氨基酸8份、吡咯烷酮羧酸钠2份、乳酸钠2份、水解胶原蛋白8份和神经酰胺8份。
4.根据权利要求1所述的一种护肤大鲵混合精油,其特征在于:其原料包括以下组分:大鲵提取油20份、薰衣草精油7份、洋甘菊精油8份、玫瑰精油5份、柠檬精油5份、迷迭香精油8份、杜松精油10份、丝柏精油6份、天竺葵精油5份、甜杏仁油荷荷巴油7份、蓖麻籽油8份、椰子油12份、维生素B612份、透明质酸钠11份、茶多酚12份、水22份、多肽12份、水杨酸10份、氨基酸10份、吡咯烷酮羧酸钠4份、乳酸钠4份、水解胶原蛋白14份和神经酰胺12份。
5.根据权利要求1所述的一种护肤大鲵混合精油,其特征在于:所述乳酸钠为无色或微黄色透明糖浆状液体,其制备方法是在冷却状态下在乳酸中加入氢氧化钠进行中和,置低于50℃下真空浓缩以除去水分80%后约放置一星期,再用氢氧化钠中和,然后稀释至一定浓度即得成品,所述天竺葵精油中含有香茅醇、甲酸香茅酯、松烯、牛儿酸、牻牛儿醇、松油醇、柠檬醛、薄荷酮和多种微量矿物元素。
6.根据权利要求1所述的一种护肤大鲵混合精油,其特征在于:所述水解胶原蛋白是从经过健康检疫的动物骨骼和皮肤中提取的,用食用级稀酸洗脱骨骼和皮肤中的矿物质,提纯而成的骨或皮肤胶原蛋白:根据不同的皮肤原料(牛、猪或鱼)用碱或酸处理后,采用高纯度的反渗透水,在一定温度下提取出大分子的胶原蛋白质,再通过特殊的酶水解工艺,有效剪切大分子链,最完整地保留有效的氨基酸基团,而成为分子量在2000-5000道尔顿的水解胶原蛋白。
7.一种护肤大鲵混合精油的制备方法,具体包括以下步骤:
S1、大鲵提取油的制备:取大鲵体内的脂肪组织,将其放置于不锈钢夹层锅内,然后通入热蒸气,将内部加热至90-100℃,加热1-2小时,再对加热过后的脂肪组织进行挤压,把所得到的油液过滤、离心,得到大鲵粗油,再将大鲵粗油加热到50-70℃,加入磷酸溶液经充分混合后进入酸炼反应罐,停留10-30分钟后,静置备用,然后将所得大鲵油原料加热到50℃-95℃,加入烧碱溶液,混匀,停留10-30分钟后,静置备用,在常温下加入活性炭,搅拌10-60分钟,脱色、除臭,离心、过滤去渣,得到上清油液,将上清油液进行缓慢搅拌,控制冷却速度,冷却至0℃-10℃左右,冷却时间为12-48小时,得到大鲵提取油;
S2、第一混合液的制备:选取适量的薰衣草精油、洋甘菊精油、玫瑰精油、柠檬精油、迷迭香精油、杜松精油、丝柏精油、天竺葵精油、甜杏仁油荷荷巴油、蓖麻籽油和椰子油,将其原料倒入搅拌机中,启动搅拌机进行搅拌,将搅拌机内部的温度设置为30℃-50℃,搅拌时间设置有1-2小时,搅拌的速率控制在120-160转/分钟,使其充分混合均匀之后,得到第一混合液;
S3、第二混合液的制备:选取适量的茶多酚和水,将其混合均匀,使得茶多酚充分溶于水,然后加入适量的乳酸钠、吡咯烷酮羧酸钠、水杨酸和水解胶原蛋白,启动搅拌机进行搅拌,搅拌机运行时的温度控制在10℃-30℃,搅拌时间为20-40分钟,搅拌的速率控制在100-150转/分钟,然后加入适量的维生素B6、透明质酸钠、多肽、氨基酸和神经酰胺,再次启动搅拌机,搅拌机运行时的温度控制在40℃-60℃,搅拌时间为40-60分钟,搅拌的速率控制在150-220转/分钟,然后关闭搅拌机,将其冷却至室温,即可得到第二混合液;
S4、混合精油的制备:将S2中制得的第一混合液和S3中制得的第二混合液放入高速分散机内进行均匀分散,分散30-50分钟后,倒入S1中制得的大鲵提取油,将其进行混合均匀,并将其温度升至40℃-60℃,搅拌1-2小时后,将其倒出进行过滤,冷却之后即可得到混合精油。
8.根据权利要求7所述的一种护肤大鲵混合精油的制备方法,其特征在于:所述步骤S1中,所述磷酸溶液的浓度为60-90%,所述烧碱溶液的浓度为10%-40%。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202110171256.9A CN112932999A (zh) | 2021-02-08 | 2021-02-08 | 一种护肤大鲵混合精油及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202110171256.9A CN112932999A (zh) | 2021-02-08 | 2021-02-08 | 一种护肤大鲵混合精油及其制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN112932999A true CN112932999A (zh) | 2021-06-11 |
Family
ID=76244089
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202110171256.9A Pending CN112932999A (zh) | 2021-02-08 | 2021-02-08 | 一种护肤大鲵混合精油及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN112932999A (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113786444A (zh) * | 2021-11-02 | 2021-12-14 | 济南紫金玫瑰股份有限公司 | 一种接骨木制备的按摩油 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101721347A (zh) * | 2009-12-10 | 2010-06-09 | 张家界金鲵生物科技有限公司 | 含人工养殖大鲵组织物或提取液的美容护肤品 |
CN103666742A (zh) * | 2013-11-28 | 2014-03-26 | 张家界金鲵生物工程股份有限公司 | 一种大鲵油的提取方法及其产品 |
CN104688636A (zh) * | 2013-12-04 | 2015-06-10 | 戴铭恒 | 一种大鲵防冻裂化妆品 |
CN106176323A (zh) * | 2016-08-24 | 2016-12-07 | 登封市科技企业孵化服务中心 | 植物精油美白护肤品 |
CN108420767A (zh) * | 2018-05-15 | 2018-08-21 | 上海东晟源日化有限公司 | 一种具有抗皱紧致和美颜保湿功效的护肤品 |
CN109330969A (zh) * | 2018-11-12 | 2019-02-15 | 汉中市汉鲵食品加工有限公司 | 含大鲵油的中药洗发护发剂 |
CN110693809A (zh) * | 2019-11-21 | 2020-01-17 | 旌德县万方日用品有限公司 | 一种护肤保湿美白美容液及其制备方法 |
-
2021
- 2021-02-08 CN CN202110171256.9A patent/CN112932999A/zh active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101721347A (zh) * | 2009-12-10 | 2010-06-09 | 张家界金鲵生物科技有限公司 | 含人工养殖大鲵组织物或提取液的美容护肤品 |
CN103666742A (zh) * | 2013-11-28 | 2014-03-26 | 张家界金鲵生物工程股份有限公司 | 一种大鲵油的提取方法及其产品 |
CN104688636A (zh) * | 2013-12-04 | 2015-06-10 | 戴铭恒 | 一种大鲵防冻裂化妆品 |
CN106176323A (zh) * | 2016-08-24 | 2016-12-07 | 登封市科技企业孵化服务中心 | 植物精油美白护肤品 |
CN108420767A (zh) * | 2018-05-15 | 2018-08-21 | 上海东晟源日化有限公司 | 一种具有抗皱紧致和美颜保湿功效的护肤品 |
CN109330969A (zh) * | 2018-11-12 | 2019-02-15 | 汉中市汉鲵食品加工有限公司 | 含大鲵油的中药洗发护发剂 |
CN110693809A (zh) * | 2019-11-21 | 2020-01-17 | 旌德县万方日用品有限公司 | 一种护肤保湿美白美容液及其制备方法 |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113786444A (zh) * | 2021-11-02 | 2021-12-14 | 济南紫金玫瑰股份有限公司 | 一种接骨木制备的按摩油 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR100862979B1 (ko) | 화장품용 콜라겐 펩타이드 조성물 및 그 제조방법 | |
JP5276813B2 (ja) | エラスチン分解ペプチド並びにエラスチン及びその酵素分解ペプチドの製造方法 | |
CN107095313B (zh) | 一种胶原蛋白口服液 | |
CN110024901A (zh) | 一种胶原蛋白肽及其生产方法和生产装置以及应用 | |
KR20170036397A (ko) | 항산화활성과 항균활성의 기능성 고형샴푸비누 조성물 및 그 비누 제조방법 | |
CN101238904B (zh) | 一种鹰嘴豆豆芽汁茶及制备方法和用途 | |
KR100827389B1 (ko) | 식품용 콜라겐펩타이드 조성물 및 그 제조방법 | |
JP3635081B2 (ja) | 美白剤、抗酸化剤、コラゲナーゼ活性阻害剤、ヒアルロニダーゼ活性阻害剤、老化防止剤、皮膚外用剤、化粧料及び食料品 | |
CN105769725A (zh) | 一种迷迭香保湿水及其制作方法 | |
CN105853260A (zh) | 一种尿布皮炎霜及其制备方法 | |
CN105687081A (zh) | 一种抗衰老保湿凝胶及制备方法 | |
CN113331324A (zh) | 一种不老莓饮品(口服液)配方及制取方法 | |
KR20090087716A (ko) | 고농도 콜라겐 함유 농축형 식초 음료 제조방법 | |
CN112932999A (zh) | 一种护肤大鲵混合精油及其制备方法 | |
KR102358623B1 (ko) | 콜라겐 펩타이드를 포함하는 피부 개선용 식품 조성물 | |
JP2006257067A (ja) | クマザサ属抽出物の製造方法、クマザサ属抽出物及びその用途 | |
JP2006199626A (ja) | 酢酸菌セラミドを含む肌機能改善用組成物 | |
KR20180065188A (ko) | 마린 콜라겐을 함유한 석류음료 및 이의 제조방법 | |
CN114469817B (zh) | 细致毛孔组合物及其制备方法和应用 | |
CN105287332A (zh) | 一种包含花萃多肽的美白保湿组合物、制备方法及应用 | |
CN114041584A (zh) | 一种可以常温储运的鱼皮胶原蛋白肽冻的制作方法 | |
CN106606448A (zh) | 一种抗氧化酵素面膜液 | |
CN107048414A (zh) | 一种富含花生生物活性肽的复合蛋白质粉及其制备方法 | |
Wu SuoLian et al. | Advances in research and application of fish scale collagen. | |
CN111084311A (zh) | 一种含有鳕鱼鳔胶原蛋白肽的饮品及其制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210611 |
|
RJ01 | Rejection of invention patent application after publication |